Abstract: The invention relates to a curable composition comprising addition curable silicone component (A) having a linear siloxane backbone at least one unsaturated, non-activated side group pendant from the Si atom or atoms in the backbone, component (A) having an equivalent weight in the range of about 68 to about 1000, crosslinker component (B) comprising at least 2SiH groups, catalyst component (C) being able to catalyse the reaction between component (A) and component (B), filler component (D), wherein the equivalent weight is defined as (molecular weight of the molecule)/(number of unsaturations in the molecule).
Abstract: Compositions of cross-linked polyvinylpyrrolidone (PVP) are disclosed that are generally in the form of an elastic, hydrophilic, water-insoluble viscous cohesive mass of material that has many important medical uses including uses as a filler for implants. The present invention also involves a process for producing such compositions.
Type:
Application
Filed:
August 23, 2010
Publication date:
December 16, 2010
Inventors:
Arthur A. Beisang, Robert A. Ersek, Arthur A. Beisang, III, Daniel J. Beisang
Abstract: Improved compositions comprising a mixture of gutta-percha and a hydraulic material containing calcium silicate, calcium aluminate, calcium phosphate, and calcium sulfate compounds are provided. Preferably, the composition includes hydroxylapatite mineral. The composition is particularly suitable for obturating and sealing dental root canals. The composition should provide a stable barrier to bacterial and fluid leakage in the root canal system of a tooth. In addition, the composition should help promote the growth of new bone and tissue surrounding the root tip area.
Abstract: Methods for modulating and enhancing thermal and mechanical properties and biocompatibilities of coatings on implantable devices are disclosed. Implantable devices containing the enhanced thermal and mechanical properties and biocompatibilities are also described. The implantable devices can be used to treat a medical condition such as vulnerable plaque or restenosis.
Type:
Grant
Filed:
April 30, 2004
Date of Patent:
October 26, 2010
Assignee:
Advanced Cardiovascular Systems, Inc.
Inventors:
Syed Faiyaz Ahmed Hossainy, Yiwen Tang, Harshad Borgaonkor, Jessica Reneé DesNoyer, Stephen D. Pacetti
Abstract: Implantable medical devices having galvanic particulates are disclosed. The particulates may be coated onto at least part of a surface of the medical device. In addition, the galvanic particulates may be contained in the material used to manufacture the antimicrobial medical devices, or may be embedded into the surface of the medical devices. The present invention also provides novel coating methods and processing methods. The devices may have advantageous characteristics and effects including anti-microbial, anti-inflammatory, and tissue regeneration promoting.
Type:
Application
Filed:
April 16, 2010
Publication date:
October 21, 2010
Inventors:
Chunlin Yang, Ying Sun, Frank R. Cichocki, JR., Saumen N. Bar, James E. Hauschild, Uri Herzberg, Yufu Li, Xintian Ming, Wei Kong, Jeannette Chantalat, Michael Southall
Abstract: Poly(propylene fumarate) is copolymerized with poly(caprolactone) diol to produce a block copolymer of poly(propylene fumarate) and poly(caprolactone). The biocompatible and bioresorbable block copolymer of poly(propylene fumarate) and poly(caprolactone) is useful in the fabrication of injectable and in-situ hardening scaffolds for tissue and/or skeletal reconstruction. The block copolymer can be crosslinked by redox or photo-initiation, with or without an additional crosslinker. Thus, the copolymer is both self-crosslinkable (without the use of any crosslinkers) and photocrosslinkable (in the presence of photons such as UV light).
Type:
Grant
Filed:
November 18, 2005
Date of Patent:
October 19, 2010
Inventors:
Shanfeng Wang, Michael J. Yaszemski, Lichun Lu, Bradford L. Currier
Abstract: The invention relates to a curable composition comprising addition curable silicone component (A) having a linear siloxane backbone at least one unsaturated, non-activated side group pendant from the Si atom or atoms in the backbone, component (A) having an equivalent weight in the range of about 68 to about 1000, crosslinker component (B) comprising at least 2 SiH groups, catalyst component (C) being able to catalyse the reaction between component (A) and component (B), filler component (D), wherein the equivalent weight is defined as (molecular weight of the molecule)/(number of unsaturations in the molecule).
Abstract: Implantable medical devices having galvanic particulates are disclosed. The particulates may be coated onto at least part of a surface of the medical device. In addition, the galvanic particulates may be contained in the material used to manufacture the antimicrobial medical devices, or may be embedded into the surface of the medical devices. The present invention also provides novel coating methods and processing methods. The devices may have advantageous characteristics and effects including anti-microbial, anti-inflammatory, and tissue regeneration promoting.
Type:
Application
Filed:
March 25, 2010
Publication date:
September 30, 2010
Inventors:
Chunlin Yang, Ying Sun, Frank R. Cichocki, JR., Saumen N. Bar, James E. Hauschild, Uri Herzberg, Yufu Li, Xintian Ming, Wei Kong
Abstract: The present invention provides a polymer membrane enhanced with cured epoxy resin for use as the outer membrane of biosensors. The membrane includes approximately 30-80% epoxy resin adhesives, 10-60% polymer such as poly(vinyl chloride), polycarbonate and polyurethane and 0-30% plasticizers and 5-15% surface modifier reagent such as polyethylene oxide-containing block copolymers. Utilizing the polymer membrane of the present invention, a three-layered sensing element has been developed. This sensing element will be particularly useful for miniaturized biosensors used for in vitro blood measurements or for continuous in vivo monitoring such as implantable biosensors. This element includes an enzyme layer, an interference-eliminating layer and the novel polymer member of the present invention as the outer polymer layer. This novel sensing element shows excellent response characteristics in solutions and has an extremely long lifetime.
Abstract: The present invention relates to a fibrous scaffold for use as a substrate in soft tissue applications, in particular for preparing annulus fibrosus (AF) tissue. In aspects, the present invention also relates to an engineered biological material comprising AF tissue; constructs comprising one or more engineered biological materials; methods for producing the biological materials and constructs; and methods of using the biological materials and constructs.
Abstract: The purpose of the present invention is to demonstrate that semiconducting and non-biodegradable implants made with polypyrrole and polyethylenglycol copolymers and iodine-doped and plasma-synthesised pyrrole polymers, have a neuroprotector effect and induce the reconnection of the spinal cord after an injury; this effect was proved in a model involving a complete section of the spinal cord in rats; the results o the functional evaluation demonstrated 5 times greater recovery in animals implanted with the polypyrrole-polyethylenglycol copolymer compared with the control group which only underwent a complete section of the spinal cord; in addition, the functional recovery of the group with iodine-doped polypyrrole was ten times greater compared to the control group; in the histological study various inflammatory and immune cells were identified at the injury site in the three experimental groups with and without implants and the integration of the polymers in the nervous tissue of the spinal cord was also obse
Type:
Application
Filed:
June 1, 2007
Publication date:
September 16, 2010
Inventors:
Roberto Olayo Gonzalez, Juan Morales Corona, Rodrigo Lozano Mondragon, Ana Laura Alvarez Mejia, Juan Carlos Axayacatl Morales Guadarrama, Luis Camilo Rios Castañeda, María de los Angeles Araceli Diaz Ruiz, Guillermo Jesús Cruz Cruz, María Guadalupe Olayo González, Hermelinda Salgado Ceballos
Abstract: A variety of phase-separated biocompatible polymer compositions are described. In preferred embodiments the polymers are bioresorbable and/or biodegradable, and have desirable mechanical properties, such as fracture and/or fatigue toughness, that have previously not been a primary design criteria for such polymers. The polymer compositions are useful in a variety of medical applications, such as in the fabrication of medical devices.
Type:
Application
Filed:
October 11, 2009
Publication date:
September 9, 2010
Applicant:
Rutgers, the State University
Inventors:
Don K. BRANDOM, Durgadas Bolikal, Lioubov Kabalnova, James E. McGrath, Joachim Kohn
Abstract: A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Type:
Application
Filed:
March 3, 2009
Publication date:
September 9, 2010
Inventors:
Florian N. Ludwig, John Stankus, Mikael Trollsas
Abstract: A hydrogel is obtained by combining acrylamide and methylene bis-acrylamide, radical initiation and washing with pyrogen-free water or saline solution to give less than 3.5% by weight polyacrylamide, based on the total weight of the hydrogel. The hydrogel may be used as a soft tissue filler endoprosthesis. Also disclosed is a method of filling a soft tissue in a mammal using the endoprosthesis, and a prosthetic device comprising the polyacrylamide hydrogel.
Abstract: The present invention refers to medical devices comprising a modified Co-Polymer and the modified Co-Polymer itself having high flexibility and high stress resistance, especially tensile strength or tear resistance, in addition to the good physical characteristics of the known Block-Co-Polymers of a polyamide and a polyether, either polyether diol or polyether diamine.
Abstract: The invention provides creep resistant, lubricious and tough PV A-PAAm-hydrogels, creep resistant, lubricious, tough PVA-PAAm-hydrogel-containing compositions, and methods of making the same. The invention also provides methods of implanting or administering the creep resistant, lubricious and tough PV A-PAAm-hydrogels, or the PVAPAAm-hydrogel-containing compositions to treat a subject in need. Methods of cross-linking pre-solidified or pre-gelled hydrogel particles and making cross-linked PVA-PAAm-hydrogels, and cross-linked PVA-PAAm-hydrogel-containing compositions also are disclosed herein.
Type:
Application
Filed:
April 23, 2008
Publication date:
August 19, 2010
Applicant:
The General Hospital Corporation
Inventors:
Orhun K. Muratoglu, Hatice Bodugoz-Senturk
Abstract: The present invention provides a coating comprising a reservoir layer comprising a terpolymer comprising caprolactone and glycolide and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
Type:
Application
Filed:
May 14, 2009
Publication date:
August 19, 2010
Applicant:
Abbott Cardiovascular Systems Inc.
Inventors:
Florencia Lim, Michael Ngo, Syed Faiyaz Ahmed Hossainy, Mikael Trollsas
Abstract: Hardenable and hardened dental compositions, and articles including such hardenable and hardened compositions, are provided. In some embodiments, the hardenable dental compositions include an acid-generating component and an acid-reactive component including one or more acid-reactive groups. Upon irradiating, and optionally heating, the hardened compositions are useful, for example, for reducing the bond strength of orthodontic appliances adhered to tooth structures with the hardened compositions.
Type:
Grant
Filed:
December 20, 2005
Date of Patent:
August 17, 2010
Assignee:
3M Innovative Properties Company
Inventors:
Rajdeep S. Kalgutkar, Joan V. Brennan, Babu N. Gaddam
Abstract: The present invention provides novel antimicrobial polyurethane compositions having excellent mechanical and biocompatibility properties, and methods to prepare them. The antimicrobial polyurethane compositions include a homogenous distribution of silver ions by incorporating this antimicrobial agent into the composition prior to the complete polymerization of the polyurethane. In preferred embodiments, the silver ion is associated with a carrier, such as zirconium phosphate or soluble glass powder. The present invention also includes components made from the antimicrobial polyurethane compositions, such as medical devices.
Type:
Grant
Filed:
June 8, 2007
Date of Patent:
August 10, 2010
Assignee:
Advansource Biomaterials Corporation
Inventors:
Harold Elbridge Garey, Jr., Andrew Martin Reed
Abstract: A bone substitute composition includes glass flake and a hardenable material. The glass flake is a particle with an aspect ratio of, at least, 20:1. The preferred thickness of the glass flake is in the range from 200 to 1,000 nm and the average particle size is, preferably, from 20 to 60 ?m.
Abstract: A coating with antimicrobial agents for use with medical devices. In one approach, a related method involves coating high temperature vulcanized silicone material with a room temperature vulcanized dispersion.
Abstract: A method of injection molding produces a microcellular material. In this method, a polymer is melted and blended with a supercritical fluid to produce a single-phase polymer-gas solution. This solution is injected through a nozzle and into a mold. When injected through the nozzle, gas in the solution (from the supercritical fluid) emerges from the polymer, which then solidifies. In emerging from the solution, the gas causes the nucleation of cells that result in a microcellular structure. A foam material comprises a polymer having a microcellular structure formed by the nucleation of micro-cells. The micro-cells are formed by the dispersing of a supercritical fluid in a liquid solution of the polymer when the polymer is subjected to a pressure drop. A feminine hygiene device is fabricated from a foamed polymer.
Type:
Application
Filed:
February 5, 2009
Publication date:
August 5, 2010
Applicant:
PLAYTEX PRODUCTS, INC.
Inventors:
Eugene P. Dougherty, JR., Keith Edgett, Lih-Sheng (Tom) Turng, Adam J. Kramschuster, Jungjoo Lee, Chris Lacey, Patrick Gorton
Abstract: An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release implant formulation. Increased gains are particularly improved when zeranol is administered in an immediate-release and controlled-release formulation which allows for a one-time dosage injection.
Type:
Grant
Filed:
November 1, 1999
Date of Patent:
August 3, 2010
Assignee:
Schering-Plough Animal Health Corp.
Inventors:
Shih Chung, Thomas J. Kennedy, Peter James Knight, Daniel S. Robins, Zezhi Jesse Shao
Abstract: A one-component self-etching self-priming dental adhesive composition is disclosed. The composition comprises glycerol phosphate di(meth)acrylate monomer, at least one mono-functional polymerizable monomer having just one ethylenically unsaturated group, at least one multi-functional polymerizable monomer having at least two ethylenically unsaturated groups, at least one aprotic solvent, at least one protic solvent, and at least one polymerization initiator.
Abstract: Intraocular lenses comprised of an acrylic-silicone hybrid polymer are disclosed. The intraocular lenses described herein are suitable for insertion through incisions of 2 mm or less.
Abstract: Lactam polymers has been modified with sodium borohydride (NaBH4) to yield lactam polymers bearing hydroxyl functional groups. These functional groups are useful for the covalent attachment of reactive groups, fluorescent probes, antimicrobial agents, bioactive factors, and drugs. The resulting as components for medical devices, specifically ophthalmic devices and more specifically contact lenses. Hydrogels based on these polymers are also useful for biomedical applications in the areas of drug delivery, tissue engineering, and implantable devices.
Abstract: Brush copolymers containing (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units are disclosed.
Type:
Application
Filed:
December 18, 2009
Publication date:
July 1, 2010
Inventors:
David Paul Vanderbilt, Paul L. Valint, JR.
Abstract: The invention relates to biocompatible polycarbonate/polyamide polymer compositions for use in medical and surgical devices. Additional additives, crosslinking agents, phosphites, and optionally a radiopaque filler or fillers can be used to produce the high performance compositions desired. The polymer compositions have improved melt processability along with balanced or enhanced physical and mechanical properties, especially when combined or over-extruded onto or covering other polymer layers, such as soft and/or flexible layers commonly used in medical device applications and catheter tips, for example.
Type:
Application
Filed:
December 31, 2008
Publication date:
July 1, 2010
Inventors:
Xiaoping Guo, David P. Johnson, Richard E. Stehr
Abstract: Brush copolymers containing (a) monomeric units derived from an ethylenically unsaturated monomer containing one or more boronic acid moieties and; and (b) monomeric units derived from an ethylenically unsaturated-containing hydrophilic macromonomer are disclosed.
Type:
Application
Filed:
December 18, 2009
Publication date:
July 1, 2010
Inventors:
David Paul Vanderbilt, Paul L. Valint, JR.
Abstract: Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/?-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2<L(LA)<[LA%/(LA%+GA%+CL%)]×X×0.058??(1) 1<L(GA)<[GA%/(LA%+GA%+CL%)]×X×0.58??(2) 1<L(CL)<[CL%/(LA%+GA%+CL%)]×X×0.
Abstract: The invention provides a multi-polymer hydrogel article having a first polymeric, water-swellable material and a second polymeric material, organized such that a first region substantially comprises the first polymeric, water-swellable material, a second region adjacent the first region comprises a mixture of the first polymeric, water-swellable material and the second polymeric material, and a third region adjacent the second region substantially comprises the second polymeric material. The article exhibits an increasing concentration gradient of the second polymeric material moving from the first region, through the second region, to the third region.
Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.
Abstract: Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.
Type:
Application
Filed:
December 31, 2009
Publication date:
June 3, 2010
Inventors:
David C. Gale, Klaus Kleine, Anthony J. Abbate, Svava Maria Atladottir, Stephen D. Pacetti
Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.
Type:
Grant
Filed:
January 23, 2009
Date of Patent:
May 11, 2010
Assignee:
Alcon, Inc.
Inventors:
Diana M. Cordova, Mutlu Karakelle, Chance Lehman, Douglas C. Schlueter, Joseph I. Weinschenk, III
Abstract: Absorbable radiation or radiochemically sterilized medical devices, including sutures, whose breaking strength and absorption profile can be modulated by controlling the total dose received during sterilization are disclosed.
Abstract: Cell-occlusive membrane, obtainable by reaction of at least two precursors in the presence of water. The first precursor A comprises a core and n chains each having a conjugated unsaturated group or a conjugated unsaturated bond, and the second precursor B comprises a core and m chains each having a thiol group, wherein m is greater than or equal to 2, n is greater than or equal to 2, and m+n is greater than or equal to 5. The reaction forms a three dimensional network with crosslinking-points. The adjacent crosslinking-points are connected by a chain having less than 600 atoms.
Abstract: A degradable composite comprising a degradable matrix, a first fibre type and a second fibre type, wherein the first fibre type has a different rate of degradation to that of the second fibre type.
Type:
Application
Filed:
September 21, 2007
Publication date:
April 29, 2010
Applicant:
NOTTINGHAM, UNIVERSITY OF
Inventors:
Christopher Douglas Rudd, Andrew James Parsons, Gavin Stuart Walker
Abstract: A stable, phase-pure magnesium-substituted crystalline hydroxyapatite containing from about 2.0 to about 29 wt % magnesium, wherein at least 75 wt % of the magnesium content is substituted for calcium ions in the hydroxyapatite lattice structure.
Type:
Grant
Filed:
March 25, 2005
Date of Patent:
April 27, 2010
Inventors:
Richard E Riman, Wojciech Suchanek, Pavel Shuk, Kevor S. TenHuisen, Chun-Wei Chen
Abstract: Novel osteogenic compositions and methods are provided. In a broad aspect, the composition comprises either a first amino acid sequence which is capable of being phosphorylated by CAMK2; or a nucleic acid sequence encoding the first amino acid sequence; or a combination thereof. Optionally, the first amino acid sequence may further comprise a second amino acid sequence which is capable of binding the Smurf1 protein. Further, the composition may comprise a BMP protein and/or an agent capable of decreasing an amount or an activity of CAMK2. The compositions of the instant invention may be incorporated into an implant or delivered via a catheter.
Abstract: A coating with antimicrobial agents for use with medical devices. In one approach, a related method involves coating high temperature vulcanized silicone material with a room temperature vulcanized dispersion.
Abstract: An assembly comprises first and second parts which bear against one another, wherein said first part comprises a polyetherketone and said second part comprises a polyetherketone. The parts bear against one another such that one or both of the parts may have a tendency to wear and/or produce wear debris by virtue of contact between the parts. The materials used, however, minimise wear and the production of such wear debris.
Abstract: Implantable nerve regeneration conduits and methods of making the same are disclosed. The implantable nerve regeneration conduits mainly comprise a biodegradable polymer and a metal. Moreover, the conduits may also comprise one or more nerve regeneration enhancing elements, which comprise bioactive molecules or cells. The inner surface of the conduits may be micropatterned photolithographic processes to form microgrooves for facilitating cell alignment.
Abstract: To provide a dental restorative material composition using an organic-inorganic composite filler having excellent surface smoothness like a natural tooth, low polymerization shrinkage, excellent X-ray contrast imaging property, similar transparency to that of a natural tooth, and no variation of transparency before and after the composition is hardened, the dental restorative material composition includes (a) a (meth)acrylate monomer, (b) an organic-inorganic composite filler having an average particle diameter of 5 to 50 ?m which is made by mixing a (meth)acrylate monomer and a fine particle filler having an average primary particle diameter of 0.005 to 0.3 ?m and having X-ray impermeability, (c) a fine particle filler having an average primary particle diameter of 0.005 to 0.04 ?m, and (d) a photopolymerization initiator.
Abstract: A composition comprising polymer particles and a carrier, wherein the polymer particles are a mixture of at least a first polymer and a second polymer, wherein the first polymer is at least partially soluble or dispersible in the carrier, and wherein the polymer particles are arranged such that they can join together to form a scaffold of polymer particles, and wherein the composition is administrable to a human or non-human animal.
Type:
Application
Filed:
February 1, 2008
Publication date:
March 11, 2010
Applicant:
REGENTEC LIMITED
Inventors:
Patrick Ginty, Robin Andrew Quirk, Kevin Morris Shakesheff
Abstract: In preferred embodiments, the present invention provides methods of controllably making a vinyl polymer hydrogel having desired physical properties without chemical cross links or radiation. The gelation process is modulated by controlling, for example, the temperature of a resultant vinyl polymer mixture having a gellant or using active ingredients provided in an inactive gellant complex.
Abstract: A self-sealing shell useful as a component of a soft fluid-filled prosthetic implant is provided. The shell is at least partly constructed of a wall made of a colloid of an elastomeric polymer matrix and particles of a water-soluble material distributed therein.
Abstract: A composition of matter and method for preparation of a tissue augmentation material. A polysaccharide gel composition is prepared with rheological properties selected for a particular selected application. The method includes preparing a polymeric polysaccharide in a buffer to create a polymer solution or gel suspending properties in the gel and selecting a rheology profile for the desired tissue region.
Abstract: Dental materials which contain a radically polymerizable organic binder, at least one radical polymerization initiator and at least one radical polymerization accelerator, both the initiator and the accelerator each having at least one radically polymerizable group.
Type:
Grant
Filed:
December 17, 2004
Date of Patent:
February 9, 2010
Assignee:
Ivoclar Vivadent AG
Inventors:
Norbert Moszner, Urs Karl Fischer, Peter Burtscher, Jörg Angermann, Volker M. Rheinberger
Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.
Type:
Application
Filed:
June 26, 2009
Publication date:
January 28, 2010
Applicant:
Cardiac Pacemakers, Inc.
Inventors:
Shrojalkumar Desai, Marlene C. Schwarz, Mark Boden, Mohan Krishnan, Michael C. Smith, Frederick H. Strickler, Daniel J. Cooke