Abstract: The invention provides composite materials that form a biocompatible and bioresorbable settable ceramic-forming composition, and that possesses high strength when set and other desirable mechanical properties. The composite materials may include additive materials that provide beneficial advantages in the handling and physical properties of the material. When a hydrated precursor, the composite material is capable of being injected through cannulas for placement in treatment sites. The composite material provided desirable handling properties and sets in a clinically relevant time period.

Abstract: Bioactive, ceramic medical cements and methods for its use in treatment of bones and teeth in mammals are disclosed. This cement is non-exothermic and non-toxic, based upon setting of hydraulic ceramic compounds containing calcia, alumina, and silica phases. The self-hardening cement sets in vivo and in high humidity environments, and can be used in vivo without being easily washed out of the site. It also has dimensional stability, is resistant to acids present in an infection site or supragingivally, and has biocompatibility advantages of low inflammation and the formation of calcification layers in direct apposition to body tissue. Options include the addition of various radiopaque materials, and a variety of delivery systems including powder and liquid, capsule or pouch delivery, multiple pastes, or a unitary paste.

Abstract: Provided are reactive silicon group-containing polymers and a curable composition containing said polymers. The curable composition provides a cured product having a low modulus, flexibility, excellent tensile strength, tensile elongation, and tear strength. The curable composition can also exhibit excellent rapid curing properties even when a low-activity catalyst has been added. In the reactive silicon group-containing polymer, a reactive silicon group, indicated by general formula (1): (—Si(R1)3-a(X)a), is bonded to the molecular chain of the polymer and an atom adjacent to the reactive silicon group has an unsaturated bond. In general formula (1), each R1 can independently indicate a C1-20 hydrocarbon group, and the R1 hydrocarbon groups can be substituted and a hetero-containing group can be used. X can be a hydroxyl group or a hydrolyzable group, and a is 1, 2, or 3.

Abstract: Provided herein are settable and non-settable compositions for use in surgical procedures comprising a variety of disclosed particles and optionally including previously unclotted, lyophilized, optionally crosslinked mammalian blood plasma. Also provided are related compositions, including surgical kits and packages, as well as methods of making and using the compositions.

Abstract: A dental gypsum slurry includes water and a dental gypsum powder containing hemihydrate gypsum and a polycarboxylic acid salt-based water-reducing agent, wherein a powder-water ratio of the water to the dental gypsum powder is 0.24 to 0.50, and when the water and the dental gypsum powder being mixed are poured up to a height of 50 mm in a cylindrical mold having an inner diameter of 35 mm, which is vertically placed on a flat surface, and then, the cylindrical mold is pulled upward at 10 mm/s at 30 seconds after start of mixing so that a mixture spreads planarly, the diameter of the mixture is 141.4 mm or more.

Abstract: A radiation curable composition including at least one radiation hardenable component, a photo-initiator, and a filler material having a population of particulates in an amount greater than or equal to 50% by weight of the printable composition. The population of particulates exhibits a median diameter (D50) of greater than or equal to 0.3 micrometer on a volume-average basis as determined using the Particle Size Test Method, and the radiation curable composition exhibits a viscosity of less than or equal to 150 Pa s when measured using the Viscosity Test Method. A method, apparatus, and systems for producing composite articles by selectively exposing a portion of the radiation curable composition to a source of actinic radiation to at least partially cure the exposed portion of the radiation curable composition, thereby forming a hardened layer, preferably by an additive manufacturing process such as stereophotolithography, are also described. The composite articles may include composite dental restorations.

Abstract: Provided is a polymerizable liquid (or “resin”) for producing three-dimensional objects by additive manufacturing, which may include one or more of: (a) a polyvinyl siloxane; (b) a polythiol crosslinker; (c) a photoinitiator (e.g., a free radical photoinitiator); (d) optionally, a urethane (meth)acrylate oligomer; (e) optionally, a reactive diluent; (f) optionally, but in some embodiments preferably, a pigment or dye; (g) optionally, but in some embodiments preferably, a reactive or non-reactive filler; and (h) optionally, an odor scavenger.

Abstract: A dental glass ionomer cement composition that exhibits high mechanical properties. In particular, the dental glass ionomer cement composition of the present disclosure comprising (a) non-crosslinked polyalkenoic acid, (b) water, (c) crosslinked polyalkenoic acid: 0.01 to 10 wt. %, and (d) acid-reactive glass powder, exhibits extremely high compressive strength by including the crosslinked polyalkenoic acid in the specified content range.

Abstract: A dental curable composition which comprises a radically polymerizable monomer component (A), a polymerizing catalyst (B) and an inorganic granular material (C), characterized in that: the radically polymerizable monomer component (A) contains a bifunctional monomer (A-1) represented by the following formula (?), RP—SP1—RP??(?) where, RP is a radically polymerizable group represented by CH2?C(R)—COO— or CH2?C(R)—CONH—, wherein R is a hydrogen atom or a hydrocarbon group having 1 to 3 carbon atoms, and SP1 is a hydrocarbon group having 5 to 15 carbon atoms, and the content of the bifunctional monomer (A-1) in the radically polymerizable monomer component (A) is 5 to 40% by mass under a condition that the content of a diluting monomer (A-2) represented by the following formula (?), RP—SP2—RP??(?) where, RP is as defined in the above formula (?), and SP2 is an aliphatic hydrocarbon group different from SP1, an oxygen-containing aliphatic hydrocarbon group having not less than 2 oxygen atoms, or an ox

Abstract: A dental polymerizable composition includes a first component containing a (meth)acrylate free of an acid group, a (meth)acrylate having a carboxyl group, a basic filler, and an organic peroxide; and a second component containing a (meth)acrylate free of an acid group, a vanadium compound, and a thiourea derivative.

Abstract: Provided are monomers useful for dental materials that include a compound in which a core and a specific terminal group are bonded to each other directly or via a linking group, wherein the core is a C1-200 polyvalent organic group having a valence of not less than 3 containing an oxygen atom or a nitrogen atom in which an atom bonded to the terminal group or the linking group is the oxygen atom or the nitrogen atom; the terminal group is a specific (meth)acryloyl group-containing group, a (meth)acryloyl group, a C1-20 hydrocarbon group or a hydrogen atom, and the terminal group needs to meet specific requirements; and the linking group is a specific divalent group, and when the compound contains a plurality of linking groups, the linking groups may be the same as or different from each other. Compositions, dental materials and kits are also provided.

Abstract: Provided are methods and compositions relating to a dental composition more specifically to prepare the damaged dentin of the tooth for animals and pets such as canine, feline and members of the taxonomic family Equidae prior to repair. The dental compositions include a bioactive glass and a non-aqueous solvent comprising an alcohol, anti-inflammatory and anti-pain reliever.

Abstract: To provide a resin cured body for dental cutting processing used for cutting and machining using a dental CAD/CAM system, wherein the resin cured body consists of the cured body of a composition comprising: (a) an inorganic filler containing 55 wt. % or more of an element belonging to group II and/or group XIII of the periodic table in terms of an oxide, (b) a polymerizable monomer, and (c) a polymerization initiator.

Abstract: Provided are methods and compositions relating to a dental composition more specifically to prepare the damaged dentin of the tooth prior to repair. The dental compositions include a bioactive glass and a non-aqueous solvent comprising an alcohol, anti-inflammatory and anti-pain reliever.

Abstract: A dental self-adhesive resin cement is provided comprising a two-component system. A first catalyst component includes one or more acidic monomers. A second base component includes one or more basic fillers. The mixture of the first and second components is polymerizable and has an initial pH that is acidic immediately after mixing and a pH of at least about pH 8 after polymerization.

Abstract: The present invention provides methods and compositions for promoting dental tissue repair and/or regeneration, methods for promoting differentiation of dental pulp stem cells, methods for treating periodontal diseases, and methods for treating infection of a dental pulp in a subject in need thereof by contacting the tissue with a composition comprising a triacrylate capable of promoting dental pulp stem cells adhesion and/or proliferation.

Abstract: Disclosed herein are curable glass ionomer compositions that include a first paste and a second paste, and methods for using the disclosed compositions. The first paste includes water, a polyacid, and a non acid-reactive filler. The second paste includes water and an acid-reactive filler. At least one of the first paste and the second paste further includes substantially crystalline inorganic fibers. In some embodiments, the water content of the first paste and the second paste of the paste/paste GI composition disclosed herein is less than 20% by weight, based on the total weight of the composition.

Abstract: A direct filling composite resin restorative featuring a CTE that is similar to dentin and an antimicrobial is disclosed. The exemplary anti-microbial compound is zinc oxide. The CTE of the direct filling composite resin restorative is in the range of 12-15 ppm/° C. The low CTE is achieved by high filler loading of a trimodal distribution of low CTE filler. By maintaining a CTE substantially similar to that of dentin, the “Marginal Percolation” phenomenon is minimized, which decreases the incidence of secondary caries.

Abstract: The present invention relates to an aqueous dental composition having a pH of at most 7. Furthermore, the present invention relates to the use of a specific composition for the preparation of an aqueous dental composition.

Abstract: To provides a polymerizable composition having high storage stability and high color stability. To provide a two-paste type dental polymerizable composition of the present invention is a two-paste type dental polymerizable composition comprising a first paste containing (A) at least one kind of polemerizable monomer, an (B) organic peroxide as a chemical polymerization initiator, and a (C) basic filler, and a second paste containing (A) at least one kind of polemerizable monomer, a (C) basic filler and an (D) aromatic amine compound as a chemical polymerization accelerator, wherein the second paste contains 30 to 80 parts by weight of the (C) basic filler based on 100 parts by weight of the total amount of the second paste.

Abstract: To provide an organic-inorganic composite filler containing; a polymerizable monomer (a) having at least one functional group selected from the group consisting of —OH group, —NH— group, and —NH2 group, a polymerizable monomer (b) having no functional group selected from the group consisting of —OH group, —NH— group, and —NH2 group, a polymerization initiator (c), an inorganic filler (d), and a silane compound (e) which generates —OH group by hydrolysis.

Abstract: The invention relates to hardenable ceramic bone substitute compositions having improved setting, powders for such compositions and methods for their manufacture and use in medical treatment. More specifically the invention relates to hardenable bone substitute powder and hardenable bone substitute paste with improved setting properties, comprising calcium sulfate and heat-treated hydroxyapatite (passivated HA), which bone substitute is suitable for treatment of disorders of supportive tissue such as bone loss, bone fracture, bone trauma and osteomyelitis.

Abstract: To provide a glass ionomer cement having excellent removality of the excess cement after setting because of having shape retaining property where a kneaded material does not drip and flow by their own weights, few risk of water sensitivity and excellent operability at the bonding such that excess cement can be removed easily after an application in an oral cavity in an early timing in spite of exhibiting a thin film thickness at the bonding. A dental glass ionomer cement composition for luting comprises at least; a component (a) acid reactive glass powder having an average particle diameter within a range of 4.5 to 7.0 ?m, a component (b) polymer of an acid group-containing polymerizable monomer having a weight average molecular weight within a range of 30000 to 100000, a component (c) chelating agent and a component (d) water, wherein a plastic flow distance of a kneaded material before setting is 2 mm or less, and a removal possible time of an excess cement is 2 minutes or less.

Abstract: Disclosed is a resin modified dental luting cement composition having a polymerizable resin component, a polyacidic polymer component, a filler component, a redox initiator system, and water.

Abstract: The present invention provides a bone cement composition kit. The bone cement composition kit includes a bone matrix component and a hydrogel component, respectively stored in separate containers, wherein the bone matrix component includes a bone matrix, the hydrogel component includes an acrylic polymer and an acrylic monomer. A ratio of the bone matrix component to the hydrogel component is in a range from about 1:2 (mL/mL) to about 1:50 (mL/mL).

Abstract: Described herein are directed to dental filler particles and methods of making the same. The dental filler particles include a polymer coating with a plurality of ethylenically unsaturated groups on the surface of the coating. Also described herein are dental restorative materials comprising the particles.

Abstract: The present invention relates to a polymerizable polyacidic polymer and to a process for preparing the polymerizable polyacidic polymer. Furthermore, the present invention relates to an aqueous dental composition comprising the polymerizable polyacidic polymer, to a use of the polymerizable polyacidic polymer for the preparation of a dental composition and to an acrylic acid derivative copolymer.

Abstract: A novel photocurable resin composition including: a polymer with a weight average molecular weight of 1,000 to 50,000, the polymer having a structural unit of formula (1), and having a structure of formula (2) at an end: wherein X is a C1-6 alkyl group, vinyl group, allyl group, or glycidyl group; m and n are each independently 0 or 1; Q is a divalent hydrocarbon group having a carbon atom number of 1 to 16; Z is a divalent linking group having a carbon atom number of 1 to 4, wherein the divalent linking group is attached to the —O— group in formula (1); and R1 is a hydrogen atom or methyl group; a radical photopolymerization initiator; and a solvent.

Abstract: A novel photosensitive adhesive composition including the following components (A), (B), (C), and (D): Component (A): a polymer having a structural unit of the following formula (1) and a structure of the following formula (2) at a terminal, Component (B): a polymer having the structural unit of formula (1), and a carboxy group or hydroxy group at a terminal, Component (C): a radical photopolymerization initiator, and Component (D): a solvent, wherein the content by mass of the component (B) is larger than that of the component (A), (wherein X is a C1-6 alkyl group, a vinyl group, an allyl group, or a glycidyl group, m and n are each independently 0 or 1, Q is a divalent C1-16 hydrocarbon group, Z is a divalent C1-4 linking group, the divalent linking group being bonded to an —O— group in formula (1), and R1 is a hydrogen atom or a methyl group.

Abstract: Provided herein are photopolymerizable monomers, optionally for use as reactive diluents in a high temperature lithography-based photopolymerization process, a method of producing polymers using said photopolymerizable monomers, the polymers thus produced, and orthodontic appliances comprising the polymers.

Abstract: The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.

Abstract: The invention relates to a process for free radical-induced cationic frontal polymerization of cationically polymerizable monomers using a combination of at least one cationic polymerization initiator and at least one activator for said at least one initiator, characterized in that benzopinacol is used as said activator.

Abstract: An intentionally activated frangible bonding system comprises a frangible adhesive, adhesive primer, composite material matrix, and/or the like, having a polydispersion of at least one additive spread throughout the frangible bonding material. The additive degrades a bond provided by the frangible bonding material, upon application of a specific energy to the frangible bonding material. An energy emitter is configured to selectively direct the specific energy toward a structure or assembly comprising components bonded by the frangible bonding material to degrade the frangible bonding material bonding the components for disassembly.

Abstract: A polymethylmethacrylate bone cement is produced by a method. The method comprises the steps of a) providing a cement powder comprising: at least one particulate polymethylmethacrylate or polymethylmethacrylate-copolymer wherein the at least one particulate polymethylmethacrylate or polymethylmethacrylate-copolymer have a particle size of less than 100 ?m; an initiator; and at least one particulate or fibrous additive that is insoluble in methylmethacrylate, wherein the additive has an absorption capacity at room temperature of more than or equal to 0.6 g methylmethacrylate per gram of additive; b) providing a monomer solution comprising: at least one methylmethacrylate; and at least one activator; and c) mixing the cement powder and the monomer solution, characterised in that the mixing takes place without the application of shearing forces.

Abstract: Conventional dental cements lack certain properties such as the facilitation of optimal re-mineralization. The novel bioactive glass-ionomer dental and bone cement formulations disclosed herein induces mineralization at the in vivo interface and exhibits superior handling properties (shorter setting time) and mechanical properties (improved bond strength to dentin and flexural strength). The present invention presents the first bioactive glass-ionomer dental cement with mineralization power, exhibiting improved bond strength to tooth structure, sharp setting time and superior mechanical strength. Materials of this invention can be used as bone cement, as a dental filling (restorative material), as a liner for deep cavity preparations (to avoid root canal therapies and tooth sensitivity), or as a luting cement to cement dental crowns. Moreover, it can be utilized in a flowable resin for use as a coating to prevent dental caries in their initial steps (white spots).

Abstract: A device for mixing a bone material with a liquid is provided. The device comprises a chamber having a proximal end and a distal end, and the bone material disposed within the chamber, the bone material comprising a coherent mass of milled and lyophilized demineralized bone fibers; and a plunger having at least a portion slidably disposed within the proximal end of the chamber and configured to dispense the bone material mixed with liquid from the distal end of the chamber, when the plunger is in an extended position.

Abstract: The present invention relates to an aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble, polymerizable polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the polymerizable polymer has a polymer backbone and hydrolysis-stable pendant groups having one or more polymerizable carbon-carbon double bonds, wherein the polymerizable polymer is obtainable by a process comprising a) a step of copolymerizing a mixture comprising (i) a first copolymerizable monomer comprising at least one optionally protected carboxylic acid group and a first polymerizable organic moiety, and (ii) a second copolymerizable monomer comprising one or more optionally protected primary and/or secondary amino groups and a second polymerizable organic moiety, for obtaining an amino group containing copolymer; b) a step of coupling to the amino group containing copolymer a compound having a polymerizable moiety and a functional

Abstract: A kit for providing a polymerizable resin system is disclosed, which kit comprises a first Part A and a second Part B, which Part A and Part B upon mixing provides a working period of intermediate stage polymerization in which the mixture obtains a desired cohesiveness for a predetermined period of time. The first Part A comprises an acid and the second Part B comprises an organic compound that is water soluble or partially water soluble and that, in the presence of the acid, initiates curing of polymerizable monomer and/or resin that is present in Part A, Part B, or both. Also disclosed is a method of using the mixed composition as an adhesive, cement, glue, sealant, a base liner, a capping agent, a material for surface or structural repair and/or filling, an encasing material, a bodily implant, a dental material, and/or as a polymeric object having a living polymer surface property.

Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.

Abstract: Methods according to the present invention decolorize a polymer by mixing a solution of the polymer with a photocatalyst and exposing the mixture to ultraviolet light; by way of non-limiting example, the polymer may be a star polymer and the photocatalyst may be titanium dioxide. Methods according to the present invention also utilize a metal scavenger, in some embodiments a solid-phase metal scavenger, to remove a metal catalyst from a polymer solution; by way of non-limiting example, the metal catalyst may be a tin catalyst. The decolorization methods and the catalyst removal methods of the present invention may be practiced separately, sequentially in any order, or simultaneously.

Abstract: An aspect of the present invention relates to a dental cement that includes a first agent including an organic peroxide and a (meth)acrylate; and a second agent including a thiourea derivative, an ascorbate, a vanadium compound, and a (meth)acrylate, where the first agent and the second agent each have a water content that is less than or equal to 1 mass %.

Abstract: Enteric elastomers and related methods are generally provided. In some embodiments, the enteric elastomer is a polymer composite. Certain embodiments comprise a polymer composite in which hydrogen bonds within two carboxyl group-containing polymers cross-link the polymer networks into an elastic and pH-responsive polymer composite. Advantageously, this polymer composite has the capacity of being stable and elastic in an acidic environment such as that of the stomach but can be dissolved in a neutral pH environment such as that of the small and large intestines. In some embodiments, the polymer composites described herein comprise a mixture of two or more polymers with carboxyl functionality such that the two or more polymers form hydrogen bonds. In certain embodiments, the polymer composite has both enteric and elastic properties.

Abstract: Dental cement compositions (including two-part compositions), kits, and related methods are used for bonding a dental prosthetic appliance to a tooth. A first part includes an amine activator component and a zinc oxide reactive filler, while a second part includes a polymerization initiator (e.g., benzoyl peroxide) and a polymerizable component having a structure including at least one acrylate or methacrylate group at one end and a carboxylic acid group at another end. A temporary cement composition advantageously exhibits reduced compressive and/or bonding strength relative to permanent cement compositions, which provides sufficient strength to facilitate normal use of the teeth while the provisional appliance is in use, while also facilitating easy removal of the provisional appliance for replacement with a permanent appliance at a later time.

Abstract: The present disclosure provides a composite material, a method of making and using the composite material and dental products made by hardening the composite material. The composite material includes a polymerizable component, ceramic fibers and nanoclusters. Each of the ceramic fibers of the composite material has a length and where the length of fifty percent of the ceramic fibers, based on a total number of the ceramic fibers, is at least 50 micrometers and the length of ninety percent of the ceramic fibers, based on the total number of the ceramic fibers, is no greater than 500 micrometers. The composite material can also include discrete non-fumed metal oxide nanoparticles. The composite material can be hardened to become any one of a dental restorative, a dental adhesive, a dental mill blank, a dental cement, a dental prostheses, an orthodontic device, an orthodontic adhesive, a dental casting material or a dental coating.

Abstract: The present invention relates to a polymerization catalyst having storage stability under an oral cavity environment. Furthermore, the present invention relates to a dental material cured by use of the present polymerization catalyst. The polymerization catalyst for use in the dental material is achieved with including 1-cyclohexyl-5-propylbarbituric acid and trioctylmethylammonium chloride.

Abstract: To provide a two-paste type sealer composition for root canal filling consisting of a first paste containing a polymer (a) of an acid group-containing polymerizable monomer in which a portion or the entirety of the acidic group in a molecule forms a salt with an alkaline metal, a non-acid reactive powder (b) and water (c), wherein the pH of the first paste is in the range from 3.5 to 5.5, and a second paste containing an acid reactive inorganic powder (d), water (c) and a thickener (e), wherein, a cured product of a kneaded material of the first paste and the second paste comprises 3 to 20 part by weight of the polymer (a), 15 to 60 part by weight of the water (c), and 30 to 70 part by weight of the acid reactive inorganic powder (d).

Abstract: An aqueous dental glass ionomer composition comprising (A) a reactive particulate glass, (B) a water-soluble polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, (C) a water-soluble, hydrolysis-stable monomer having a single polymerizable double bond and optionally a carboxylic acid group or hydroxyl group; (D) a water-soluble, hydrolysis-stable polymerizable crosslinker having at least two polymerizable carbon-carbon double bonds; and (E) a polymerization initiator system.

Abstract: A cohesive bone composition is made from a moldable bone composition intermixed with a bone gel composition. The cohesive bone composition is made from human cadaver bone. A fluid can be added, the fluid may also be laden with cells.

Abstract: Disclosed are biomimetic mineral based endodontic cement compositions. An endodontic cement comprises a paste A and a paste B. The paste A comprises a pozzolanic cementitious mineral paste and the paste B is a mixture comprising polyanionic polymers, phosphates, cement setting modulators, host-inclusion particles, bioactive glasses, and radiopacity agents suspended in a liquid carrier.

Abstract: A temporary root canal sealer dispersion having a pH of at least 9 and comprising: (i) an aqueous dispersion medium comprising an oligomer and/or polymer having Lewis basic groups, and optionally a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal, and (ii) a dispersed phase comprising a radio-opaque filler, wherein the weight ratio of oligomer and/or polymer having Lewis basic groups to hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is at least 0.5 when said aqueous dispersion medium comprises a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal.