From Carbohydrate Or Derivative As A Reactant Patents (Class 527/300)
  • Patent number: 10308772
    Abstract: The present invention provides a method for producing an aqueous dispersion of pseudopolyrotaxane that enables the production, by an industrially advantageous method for an aqueous dispersion of pseudopolyrotaxane in which the inclusion amount of a cyclodextrin does not increase with time and which can provide a crosslinked polyrotaxane having sufficient stretchability and breaking strength. The present invention relates to a method for producing an aqueous dispersion of pseudopolyrotaxane containing pseudopolyrotaxane particles in which a polyethylene glycol is included in a cavity of a cyclodextrin molecule in a skewered manner, the method including: an inclusion step of mixing a polyethylene glycol and a cyclodextrin in an aqueous medium to include the polyethylene glycol in a cavity of a cyclodextrin molecule, wherein in the inclusion step, a basic compound is added.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: June 4, 2019
    Assignees: Sumitomo Seika Chemicals Co., Ltd., Advanced Softmaterials Inc.
    Inventors: Naohisa Hayamizu, Hiroki Okazaki, Akira Kimura, Shinya Okazaki
  • Patent number: 9783996
    Abstract: Building panels with a homogenous decorative surface having a wear layer comprising fibers, binders and wear resistant particles.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: October 10, 2017
    Assignee: VALINGE INNOVATION AB
    Inventors: Darko Pervan, Kent Lindgren, Jan Jacobsson, Niclas Håkansson, Eddy Boucké, Göran Ziegler
  • Patent number: 9505896
    Abstract: A method for making foamed thermoplastic materials includes processing a composition that contains (a) at least one thermoplastic material selected from one or more polyhydroxyalkanoates (PHAs), poly(lactic acid) (PLA), or combinations thereof; and (b) at least one organic peroxide under conditions effective to permit the composition to foam. The foamed thermoplastic materials provide a low density and lightness in weight, can be used in a variety of useful articles spanning many industries, and can have, depending on the choice of thermoplastic materials, excellent biodegradability compared to foamed polymers derived from non-renewable resources.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: November 29, 2016
    Assignee: Arkema Inc.
    Inventor: Zuzanna Donnelly
  • Patent number: 9475908
    Abstract: The present invention aims to provide an industrially advantageous method for producing an aqueous dispersion of pseudopolyrotaxane enabling to produce an aqueous dispersion of pseudopolyrotaxane having good fluidity and excellent dispersion stability of the pseudopolyrotaxane particles therein. The present invention relates to a method for producing an aqueous dispersion of pseudopolyrotaxane. The method includes: a mixing step of a dissolving polyethylene glycol and a cyclodextrin in an aqueous medium to prepare a mixed solution; and a cooling step of continuously or intermittently cooling the mixed solution in a state of flux to precipitate pseudopolyrotaxane particles. The pseudopolyrotaxane particles contain the polyethylene glycol which is included in the cavities of the cyclodextrin molecules in a skewered manner.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: October 25, 2016
    Assignees: Sumitomo Seika Chemicals Co., Ltd., Advanced Softmaterials Inc.
    Inventors: Tomoaki Yamasaki, Shinya Okazaki, Hiroki Okazaki, Shigeki Hamamoto, Changming Zhao
  • Patent number: 9339549
    Abstract: A cationic graft-copolymer for a drug delivery system comprising a unit derived from a having a hydroxyl groups, namely, a cationic polysaccharide of the following formula (1) (C6H7O2(OH)3-a (OX)a)xH2O (1) and a unit derived from a polymerizable olefin compound of the following formula (2) (a, x, X, R4, R5, R6, and R7 are defined in claim 1-8); a process for preparing the same and a transfection reagent made therefrom.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: May 17, 2016
    Inventor: Yasuhiko Onishi
  • Patent number: 9150788
    Abstract: The present invention relates to a non-amphiphile-based water-in-water emulsion composition. The non-amphiphile-based water-in-water emulsion composition includes a water-soluble polymer, a non-amphiphilic lyotropic mesogen encapsulated by the water-soluble polymer; and water. In one embodiment, the non-amphiphilic lyotropic mesogen includes, without limitation, a lyotropic chromonic liquid crystal, and more specifically disodium cromoglycate (DSCG). In another embodiment, the water-soluble polymer can include, without limitation, a polyacrylamide, a polyol, a polyvinylpyrrolidone, a polysaccharide, or a water-soluble fluoride-bearing polymer. The present invention also relates to a porous hydrogel made with the use of the non-amphiphile-based water-in-water emulsion. The present invention further relates to using the emulsion and hydrogel for various applications.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: October 6, 2015
    Assignee: Syracuse University
    Inventors: Yan-Yeung Luk, Karen A. Simon, Dacheng Ren
  • Patent number: 9120901
    Abstract: The present invention aims to provide an industrially advantageous method of producing a pseudopolyrotaxane with a high inclusion ratio. The present invention relates to a method for producing a pseudopolyrotaxane, including: an inclusion step of mixing a polyethylene glycol and a cyclodextrin in an aqueous medium to form an aqueous dispersion of pseudopolyrotaxane that contains pseudopolyrotaxane particles in which the polyethylene glycol is included in the cavities of the cyclodextrin molecules in a skewered manner; and a drying step of drying the aqueous dispersion of pseudopolyrotaxane produced in the inclusion step to obtain the pseudopolyrotaxane. In the drying step, the aqueous dispersion of pseudopolyrotaxane is dried in a thin film state.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: September 1, 2015
    Assignees: Sumitomo Seika Chemicals Co., Ltd., Advanced Softmaterials Inc.
    Inventors: Tomoaki Yamasaki, Shinya Okazaki, Hiroki Okazaki, Shigeki Hamamoto, Changming Zhao
  • Patent number: 9051406
    Abstract: Graft dendrite copolymers derived from at least one ethylenically unsaturated first monomer, at least one second ethylenically unsaturated second monomer and a natural hydroxyl containing component as an end group. The at least one first and second ethylenically unsaturated monomers are on separate side chains of the natural hydroxyl containing component. Methods of preparing a graft dendrite copolymer are also included.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: June 9, 2015
    Assignee: AKZO NOBEL CHEMICALS INTERNATIONAL B.V.
    Inventor: Klin Aloysius Rodrigues
  • Patent number: 9012415
    Abstract: This invention refers to photo-crosslinked hydrogel materials based in gellan gum suitable for tissue engineering and regenerative medicine applications or as drug delivery systems. Formulations of gellan gum with different degrees of acylation serve as precursor material for insertion of a polymerizable moiety. The materials are capable of free radical polymerization with a photo-initiator at mild temperatures and exposure to ultraviolet light, enabling control of reticulation and withstanding the encapsulation of human and animal cells and/or drugs, and any combination thereof. The physicochemical and biological properties can be adjusted by combining different formulations of gellan gum and reaction conditions.
    Type: Grant
    Filed: March 26, 2011
    Date of Patent: April 21, 2015
    Assignee: Stemmatters, Biotecnologia e Medicina Regenerativa S.A.
    Inventors: Joana Catarina Da Silva Correia, Joaquim Miguel Antunes De Oliveira, João Manuel Teixeira De Oliveira, Rui Pedro Amandi Romero De Sousa, Rui Luis Gonçalves Dos Reis
  • Patent number: 8951341
    Abstract: A sizing composition for insulating products based on mineral wool, in particular on glass or on rock, includes at least one monosaccharide and/or at lest one polysaccharide, and at least one organic polycarboxylic acid having a molar mass of less than or equal to 1000. Another subject-matter of the present invention is the insulating products based on mineral fibres thus obtained and the process for the manufacture thereof.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: February 10, 2015
    Assignee: Saint-Gobain Isover
    Inventors: Boris Jaffrennou, Dominique Serughetti, Jérôme Douce
  • Patent number: 8945706
    Abstract: A polymer composition suitable for wood treatment or binding comprises a reaction product of at least a polyol and at least a crosslinking agent. The crosslinking agent has at least 2 carboxylic acid groups per molecule. A wood product comprising a wood substrate and a polymer composition as well as a wood treatment process are also disclosed.
    Type: Grant
    Filed: June 29, 2008
    Date of Patent: February 3, 2015
    Inventor: Yin Wang
  • Patent number: 8906394
    Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: December 9, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed Faiyaz Ahmed Hossainy, Eugene Michal, Thierry Glauser, Connie Kwok, Stephen Dirk Pacetti
  • Patent number: 8859706
    Abstract: The invention relates to a bioactive hydrogel as a hybrid material of heparin and star-branched polyethylene glycol with functionalized end groups, wherein the heparin is bound directly by reaction of the carboxyl groups activated with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimides/N-hydroxysulfosuccinimide (EDC/s-NHS) with the terminal amino groups of the polyethylene glycol covalently by amide bonds.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: October 14, 2014
    Assignee: Zetascience GmbH
    Inventors: Carsten Werner, Uwe Freudenberg, Dorit Meinhold, Marie-Francoise Gouzy, Petra Welzel
  • Publication number: 20140231352
    Abstract: Provided is a silica particle coated with ?-cyclodextrin, wherein said cyclodextrin is attached to said silica particle via at least one crosslinking agent and/or at least one copolymer. Also provided are methods of removing contaminants from a flowing or stationary liquid phase comprising the step of contacting said liquid phase with the silica particle coated with ?-cyclodextrin.
    Type: Application
    Filed: October 17, 2012
    Publication date: August 21, 2014
    Applicant: TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Rominder P. S. Suri, Bikash Bhattarai
  • Patent number: 8771310
    Abstract: The present invention relates to compositions and methods for improving outcomes in vascular interventional procedures. In particular, the present invention relates to compositions and methods for improving outcomes in vascular interventional procedures using an anti-no-reflow guide wire that attenuates the “no-reflow” phenomenon that is associated with negative outcomes.
    Type: Grant
    Filed: May 28, 2008
    Date of Patent: July 8, 2014
    Assignee: Adenopaint, LLC
    Inventors: Mervyn B. Forman, Edwin K. Jackson, Jianying Zhang, Zaichuan Mi
  • Patent number: 8734817
    Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: May 27, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed Faiyaz Ahmed Hossainy, Eugene Michal, Thierry Glauser, Connie Kwok, Stephen Dirk Pacetti
  • Patent number: 8613834
    Abstract: A paper coating or binding formulation comprises an aqueous polymer dispersion comprising a copolymer obtained by polymerization of an unsaturated monomer and a carbohydrate derived compound and a tetrasulfonate-based fluorescent whitening agent. The carbohydrate derived compound can be selected from the group consisting of dextrins, maltodextrins, and mixtures thereof. Methods of preparing a paper coating or binding formulation and improving the whitening properties of paper are also provided. Furthermore, paper including a copolymer obtained by polymerization of an unsaturated monomer and a carbohydrate derived compound and a tetrasulfonate-based fluorescent whitening agent is also disclosed.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: December 24, 2013
    Assignee: BASF SE
    Inventors: Peter C. Hayes, Ralph Lewis De Jong
  • Patent number: 8609081
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: December 17, 2013
    Assignee: Cerulean Pharma Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Publication number: 20130331536
    Abstract: A method of producing a material comprising nanocellulose and a polymer, comprising carrying out in-situ, ring opening of polymerisation of dry nanocellulose dispersed in a monomer to produce said material. The material can be used as a reinforcing additive for plastics, for example in the form of a plastics masterbatch.
    Type: Application
    Filed: January 5, 2012
    Publication date: December 12, 2013
    Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTT
    Inventors: Pauliina Mikkonen, Ulla Laulumaa, Pia Mikkonen
  • Patent number: 8603454
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: December 10, 2013
    Assignee: Cerulean Pharma Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Patent number: 8597551
    Abstract: Provided is an optical film using a cellulose derivative, which is used in image display devices such as liquid-crystal display devices. A liquid-crystal display device with a polarizing plate using the optical film has an excellent viewing angle property. More particularly, the present invention relates to an optical film made of a cellulose ester resin, a portion of hydrogen atoms of hydroxyl groups of which is substituted with two or more substituent groups.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: December 3, 2013
    Assignee: SK Innovation Co., Ltd.
    Inventors: Kiyup Kim, Yonggyun Cho, Sangyeup Lee, Wonyeob Kim, Wonseok Jang, Myounglae Kim
  • Patent number: 8580242
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: November 12, 2013
    Assignee: Cerulean Pharma Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kat T. Khin
  • Patent number: 8580244
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: November 12, 2013
    Assignee: Cerulean Pharma Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Patent number: 8580906
    Abstract: Provided are a polyrotaxane capable of using an aqueous solvent in a fabricating process although it has hydrophobicity, an aqueous composition having the polyrotaxane, a crosslinked body comprising the polyrotaxane, etc. The polyrotaxane comprises blocking groups located at both ends of a pseudo-polyrotaxane having cyclic molecules and a linear molecule which pierces the cavities of the cyclic molecules in a skewered manner to form a clathrate therewith so as not to detach the cyclic molecules, wherein the cyclic molecules have a group represented by Formula I, a group represented by Formula II and a group represented by Formula III. Incidentally, M represents, for example, a group derived from ring-opening polymerization of ?-caprolactone or the like, A represents a hydroxy group or the like, B represents a —COOH group or the like, and C represents A and/or B: -M-A??Formula I; -M-B??Formula II; and —C??Formula III.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: November 12, 2013
    Assignee: Advanced Softmaterials Inc.
    Inventors: Yuki Hayashi, Mariko Shibuya, Masabumi Kudoh, Masahiko Yamanaka
  • Patent number: 8580243
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: November 12, 2013
    Assignee: Cerulean Pharma Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Patent number: 8507629
    Abstract: A production method of the present invention is a production method of an organic polymer containing two or more organic ring structures and a chain structure threading through the organic ring structures. This method includes a polymerization step of forming the organic polymer, in which the organic ring structures, which are restricted from moving, are disposed at each of a particular constitutional unit, by polymerizing at least one type of monomers each of which has no ionic functional group that releases a metal ion. The above at least one type of monomers include a monomer (M) containing the organic ring structure and a chain component threading through the organic ring structure.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: August 13, 2013
    Assignee: Panasonic Corporation
    Inventors: Takayuki Takeuchi, Norihisa Mino, Nobuaki Kambe, Jun Terao
  • Patent number: 8445588
    Abstract: A water soluble copolymer includes first and second hydrophilic block segments or graft chains. The first hydrophilic block segment or graft chain contains cyclodextrin groups in at least a majority of its repeating units, and the second hydrophilic block segment or graft chain contains repeating units other than cyclodextrin groups. The first and second block segments or graft chains are covalently linked.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: May 21, 2013
    Assignee: The Regents of The University of Michigan
    Inventors: Peter X. Ma, Jianxiang Zhang
  • Patent number: 8425542
    Abstract: An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a biocompatible metallic frame member. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the biocompatible metallic frame member. The biometallic frame member may include one or more components constructed from a NiTi alloy.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: April 23, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Roham Moftakhar, Kristyn S. Masters, Wendy C. Crone, Fangmin Xu
  • Patent number: 8426528
    Abstract: Processes for preparing crosslinked polymers using biomass derived materials, such as aldaric acids and derivatives, are provided. The polymers can be used as hydrogels.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: April 23, 2013
    Assignee: E I du Pont de Nemours and Company
    Inventors: Mark Allen Andrews, Garret D. Figuly, Henry Keith Chenault
  • Patent number: 8425541
    Abstract: An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a liquid embolic agent. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the liquid embolic agent. Upon activation inside of the polymeric shell within the aneurysm, the liquid embolic agent solidifies enabling biological isolation of the aneurysm and improved patient outcomes.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: April 23, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Kristyn S. Masters, Wendy C. Crone, Roham Moftakhar, Fangmin Xu, Beverly Aagaard Kienitz
  • Patent number: 8404662
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: March 26, 2013
    Assignees: Cerulean Pharma Inc., Insert Therapeutics, Inc., Calando Pharmaceuticals, Inc.
    Inventors: Jianjun Cheng, Mark Davis, Kay T. Khin
  • Patent number: 8399431
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: March 19, 2013
    Assignees: Cerulean Pharma Inc., Insert Therapeutics, Inc., Calando Pharmaceuticals, Inc.
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Patent number: 8399590
    Abstract: A superhydrophilic amphiphilic copolymer and process for making the superhydrophilic amphiphilic copolymer includes a low molecular weight polysaccharide modified with a hydrophobic reagent, such as substituted succinic anhydride. The superhydrophilic amphiphilic copolymer system generates stable foam for use in applications, such as healthcare formulations, with low irritation of the eyes and skin.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: March 19, 2013
    Assignee: Akzo Nobel Chemicals International B.V.
    Inventors: Joseph B. Gardner, Michael J. Fevola, Frank C. Sun, Russel M. Walters
  • Patent number: 8372193
    Abstract: Disclosed herein is a thermoplastic cellulosic composition for preparing a cellulose-based masterbatch and/or a fiber with an improved breaking elongation. In one example, the thermoplastic cellulosic composition includes an esterified cellulose present in a range of about 77 wt % to about 95 wt %, polyethylene glycol present in a range of about 4.5 wt % to about 15 wt %, a bifunctional reactant present in a range of about 0.01 wt % to about 3 wt %, an initiator present in a range of about 0.01 wt % to about 0.15 wt %, and a dispersing agent present in a range of about 0.01 wt % to about 5 wt %.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: February 12, 2013
    Assignee: Taiwan Textile Research Institute
    Inventors: Su-Chen Chen, Sheng-Jen Lin, Nai-Yun Liang, Wei-Peng Lin
  • Patent number: 8349789
    Abstract: Laundry treatment composition comprising a substituted cellulose having a degree of substitution, DS, of from 0.01 to 0.99 and a specific degree of blockiness, DB, such that either DS+DB is of at least 1 or DB+2DS?DS2 is of at least 1.20, and a laundry adjunct ingredient.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: January 8, 2013
    Assignee: The Procter & Gamble Company
    Inventor: Neil Joseph Lant
  • Patent number: 8278406
    Abstract: A bioactive and biocompatible polyurethane-butanediol-glycosaminoglycan copolymer for use in medical implant devices. The biocompatible urethane component being the reaction product of 4,4?-methylene-di-(p-phenyl isocyanate) and poly(tetramethylene oxide)n and further reacted with 1,4-butanediol, wherein n=10 to 40. The bioactive glycosaminoglycan being a salt of hyaluronic acid, such as a cetylpyridinium salt acid having 5 to 10,000 repeating units or a salt of heparin, such as a dimethyldioctadecylammonium salt of heparin has 5 to 65 repeating units or a suitable salt of dermatan sulfate. The weight content of the bioactive glycosaminoglycan is an amount sufficient to render the copolymer bioactive. The copolymers described herein have excellent hemocompatibility and biocompatibility.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: October 2, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Kristyn S. Masters, Wendy C. Crone, Fangmin Xu
  • Patent number: 8268953
    Abstract: A process for the preparation of a polycarbonate containing a plant-derived component excellent in hue by using a plant-derived anhydrosugar alcohol represented by the following formula (1) or a composition thereof as a raw material: wherein R1 to R4 each independently represent a group selected from a hydrogen atom, an alkyl group, a cycloalkyl group and an aryl group.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: September 18, 2012
    Assignee: Teijin Limited
    Inventors: Akimichi Oda, Eiichi Kitazono, Ryuji Nonokawa, Takanori Miyoshi
  • Patent number: 8258250
    Abstract: Provided are compositions comprising a superhydrophilic amphiphilic copolymer and a carrier and composition comprising a superhydrophilic amphiphilic copolymer, a micellar thickener and a carrier.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: September 4, 2012
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Michael J. Fevola, Frank C. Sun, Joseph J. LiBrizzi, Joseph B. Gardner, Russel M. Walters
  • Publication number: 20120190812
    Abstract: Provided is an environmentally friendly novel plant-based polycarbonate resin. Specifically, disclosed are: a plant-based polycarbonate resin which is a polymer derived from a plant-based material having a plurality of hydroxyl groups, in which molecules of the plant-based material are linked to each other through carbonate groups to form the polymer; and a production method of the polycarbonate resin.
    Type: Application
    Filed: January 26, 2012
    Publication date: July 26, 2012
    Inventors: Yoshiaki OKABE, Hiroyuki KAGAWA, Fusao HOJO
  • Patent number: 8192712
    Abstract: A method for producing carbon using less thermal energy is disclosed. Crystalline cellulose and acidic electrolyzed water are introduced into a reaction vessel. The mixture is heated until it reaches a predetermined temperature (230° C. to 250° C.) while being stirred. When the mixture reached the predetermined temperature, this temperature is maintained, and the mixture is kept heated while being stirred for a predetermined period of time (30 minutes). Thereby, carbon is produced in the reaction vessel.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: June 5, 2012
    Assignee: Honda Motor Co., Ltd.
    Inventor: Kohichi Miyashita
  • Patent number: 8193291
    Abstract: In a solution of metal-polymer (chelate(s) and applications thereof, a metal-polymer chelate is prepared by mixing water and R—COOH soluble carbohydride molecules and/or hydroxyl or hydroxyl amino and/or carboxyl and/or carbohydrate polymers, metal salts and/or ammonia or amines. The solution of metal-polymer chelate(s) is used extensively in different technical areas including oxidation, condensation, degradation, oxidizing condensation, gas detection, artificial imitated chitosan solution, artificial imitated glucosamine, disinfectant, biochemical reaction for fermentation, biological protein and its metabolite purification, metal enzyme biocatalyst, dry activation of protein enzyme, bacteria preservation systems, oil product, plant, semiconductor, nano filtration, nano material production, nano inorganic matter, nano ceramic, nano plastic, nano textile, battery, liquid crystal, and biochip. These reactions give effects for chemical engineering, gas removal, and waste solvent treatment.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: June 5, 2012
    Inventor: Caiteng Zhang
  • Publication number: 20120046435
    Abstract: The present invention relates to novel carbohydrate polyether compositions that are soluble in aqueous media and particularly to carbohydrate polyether compositions exhibiting reverse thermogelation properties in aqueous media. Also, since the carbohydrate polyethers of the present invention can be conveniently controlled with respect to functionality, molecular weight, polydispersity index, microstructure and tertiary structure, they can be customized for use in a variety of applications.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 23, 2012
    Inventor: Alexander A. GORKOVENKO
  • Publication number: 20110294962
    Abstract: The present disclosure relates to a method of forming fibers. First and second precursors, each possessing a core and at least one functional group known to have click reactivity, are mixed in a hopper. The mixed precursors are then extruded through an extrusion die to crosslink and produce a filament. Polymerization of the first and second precursors is catalyzed by transition metal ions.
    Type: Application
    Filed: February 22, 2010
    Publication date: December 1, 2011
    Applicants: TYCO HEALTHCARE GROUP LP D/B/A COVIDIEN, SOFRADIM PRODUCTION
    Inventors: Ahmad Robert Hadba, Sebastien Ladet
  • Patent number: 8017722
    Abstract: A process for production of a plant-derived component-containing polycarbonate represented by the following formula (3): (wherein R1-R4 each independently represent a group selected from among hydrogen, alkyl, cycloalkyl and aryl, and n is the number of repeating units), by melt polycondensation using as the starting materials a specified diol, having a total content of Na, Fe and Ca of no greater than 2 ppm and a purity analysis value of at least 99.7% by gas chromatography, and a specified carbonic acid diester, having a total content of Na, Fe and Ca of no greater than 2 ppm and a purity analysis value of at least 99.7% by gas chromatography.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: September 13, 2011
    Assignee: Teijin Limited
    Inventors: Akimichi Oda, Eiichi Kitazono, Toshiyuki Miyake, Masami Kinoshita, Mizuho Saito
  • Patent number: 8013130
    Abstract: A carbon-based solid acid which has high activity and high thermal stability and is useful as an acid catalyst for various reactions such as hydration of olefins. The carbon-based solid acid for use as a catalyst is obtained by carbonization and sulfonation of an organic substance, which has a reduction rate of 10 mol % or less of acid content as measured by immersing the solid acid in hot water at 120° C. for 2 hours, is used as the acid catalyst. The organic substance to be used as the raw material for preparing the solid acid is preferably a saccharide having ?1-4 glycosidic bond (e.g. cellulose) or lignin. Amylose is also suitable as the raw material. Examples of the reaction for which the solid catalyst can be used include hydration of olefins, etherification of olefins, and acid/alcohol esterification.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: September 6, 2011
    Assignees: Nippon Oil Corporation, Tokyo Institute of Technology
    Inventors: Shinichirou Yanagawa, Hidesato Kondo, Michikazu Hara
  • Patent number: 8008376
    Abstract: Disclosed are plasticizer compositions including cyclodextrin derivatives, a flexible PVC composition with suppression of the migration of a plasticizer containing the same, and a manufacturing method thereof. The manufacturing method of the flexible PVC composition of the present invention includes steps of (S1) preparing cyclodextrin derivatives; (S2) mixing the cyclodextrin derivatives, PVC and a low molecular weight liquid plasticizer to form a plastisol; and (S3) heating the plastisol to form a solution and cooling the solution. The manufacturing method PVC-1 of the present invention may be useful to mass-produce flexible PVC with suppression of the migration of a plasticizer in a simple and economic manner without using solvents since the cyclodextrin derivatives are used as a compound that can suppress the migration of a plasticizer. The flexible PVC has an effect of reducing an amount of the migrated plasticizer without deterioration in its physical properties.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: August 30, 2011
    Assignee: Seoul National University Industry Foundation
    Inventors: Seung-Yeop Kwak, Sung-Ho Kim, Seok-Bong Lee
  • Publication number: 20110195475
    Abstract: The present invention is directed to the use of artificial polymers in the mimetization of enzymatic active sites and the carrying-out of catalysis using these artificial enzymes. Further, as used herein, an artificial enzyme refers more generally to a polymer-based scaffold for presenting specific chemically active atoms optimally for reactions, not just those that mimic natural enzymes. Various polymers can be used for this mimetization, including polyimides, polyurea, polyurethane, polyacrylic acid, and polylactic acid, as well as other polymers having properties and functionality that enable integration with natural and artificial amino acids, other molecules having nucleophilic and electrophilic groups (akin to the amine and carboxyl functionalities, respectively, of amino acids), as well as other molecules contributing unique chemical abilities not usually associated with the orthogonal functions inherent in most amino acids, i.e.
    Type: Application
    Filed: February 28, 2009
    Publication date: August 11, 2011
    Inventors: Paul Bentley, Vincent Suzara
  • Patent number: 7985794
    Abstract: A starch-polyester graft copolymer and chemically modified starch-polyester graft copolymer composition comprising a chemically modified starch or chemically modified starch-nanoclay product is described. The composition can be produced continuously in a twin-screw co-rotating extruder. The starch-polyester graft copolymer can be solvent cast, melt cast and blown into clear transparent film particularly for use in single use disposable applications and can be biodegradable.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: July 26, 2011
    Assignee: Board of Trustees of Michigan State University
    Inventors: Ramani Narayan, Sunder Balakrishnan, Yogaraj Nabar, Jean-Marie Raquez, Philippe Dubois
  • Patent number: 7981943
    Abstract: A material which comprises a polyrotaxane and a polymer and is crosslinked by irradiation with light. In the material, which comprises a first polyrotaxane and a polymer, the first polyrotaxane comprises a first cyclic molecules, a first linear molecule with which the first cyclic molecules are clathrated in a splitted state, and first blocking groups disposed respectively at both ends of the first linear molecule so as to prevent the first cyclic molecules from being released from the first linear molecule. The first polyrotaxane combines with at least part of the polymer through the first cyclic molecules by photocrosslinking reaction.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: July 19, 2011
    Assignee: The University of Tokyo
    Inventors: Kohzo Ito, Masatoshi Kidowaki
  • Patent number: 7981994
    Abstract: A cellulose acylate resin film which can suppress generation of color nonuniformity even after exposure to high temperature and high humidity when incorporated in a liquid crystal display element can be produced. The cellulose acylate resin film is heat-treated at a temperature of Tg?30° C. to Tg+20° C., Tg representing the glass transition temperature of the cellulose acylate resin, for 10 seconds to 600 seconds while conveying the cellulose acylate resin film at a tension of 2 N/cm2 to 120 N/cm2.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: July 19, 2011
    Assignee: FUJIFILM Corporation
    Inventors: Shinichi Nakai, Kiyokazu Hashimoto, Zemin Shi