Esters Patents (Class 536/32)
-
Patent number: 10975518Abstract: A method is for manufacturing cellulose microfibers in which a problem of yellowing of cellulose microfibers to be obtained was solved, and cellulose microfibers. As to a method for manufacturing cellulose microfibers, cellulose fibers are added with an additive (A) consisting of at least one of a phosphorous acid and a metal phosphite and an additive (B) consisting of at least one of urea and a urea derivative, heated and washed, then fibrillated. Also, as to cellulose microfibers, the fiber width is 1 to 1000 nm, and a part of hydroxy groups of cellulose fibers is substituted with a functional group represented by a predetermined structural formula to introduce an ester of phosphorous acid.Type: GrantFiled: February 23, 2018Date of Patent: April 13, 2021Assignee: Daio Paper CorporationInventor: Ikko Matsusue
-
Patent number: 9023830Abstract: There is disclosed a cosmetic comprises a sugar compound obtained by reacting a hydroxyl group of a saccharide, an isocyanate group-containing organopolysiloxane represented by the following general formula (1), and an isocyanate group-containing organic compound represented by the following general formula (2). As a result, there is provided a cosmetic excellent in cosmetic sustainability and storage stability that can improve such undesirable feelings of use as insufficient spreadability and stickiness, improve the solubility to not only a non-polar oil such as a silicone oil and a light liquid paraffin, but also a polar oil such as a UV-absorber, an ester oil, and a natural animal and vegetable oil, provides non-stickiness with a cosmetic containing the polar oil, and prevent adhesion of the cosmetic to clothes (secondary adhesion).Type: GrantFiled: March 21, 2013Date of Patent: May 5, 2015Assignee: Shin-Etsu Chemical Co., Ltd.Inventor: Masanao Kamei
-
Publication number: 20150105499Abstract: The present invention provides a method for producing a resin composition, which, by means of simple steps, can uniformly disperse microfibrillated plant fiber in a highly hydrophobic resin and can impart enhanced mechanical strength to a molding material obtained by molding the resin composition. The present invention further provides a resin composition having excellent heat resistance and low linear thermal expansion. The present invention relates to a method for producing a resin composition, the method including a step of mixing a thermoplastic resin or thermosetting resin (A), and modified plant fiber (b) or modified microfibrillated plant fiber (B), in the presence of an organic liquid (C), the modified plant fiber (b) or modified microfibrillated plant fiber (B) being obtained by modification with an alkyl or alkenyl succinic anhydride in a liquid capable of swelling microfibrillated plant fiber (B?) or plant fiber (b).Type: ApplicationFiled: February 26, 2013Publication date: April 16, 2015Inventors: Hiroyuki Yano, Akihiro Sato, Tomoaki Yoshimura, Yuko Igarashi, Daisuke Kabusaki, Fumiaki Nakatsubo, Hiroaki Okumura, Takeshi Semba, Kazuo Kitagawa, Hiromasa Kataoka, Kazuhiro Shintani
-
Publication number: 20150031873Abstract: A reaction product mixture is obtained from a reaction of (a) a cellulose ether with (b) an aliphatic monocarboxylic acid anhydride or with a di- or tricarboxylic acid anhydride or with a combination of an aliphatic mono-carboxylic acid anhydride and a di- or tri-carboxylic acid anhydride in the presence of (c) an aliphatic carboxylic acid. A process for precipitating an esterified cellulose ether from this reaction product mixture comprises the step of contacting the reaction product mixture with water and subjecting the combination of water and the reaction product mixture to a shear rate of at least 800 s?1. The precipitated esterified cellulose ether can be recovered as a non-tacky product.Type: ApplicationFiled: March 12, 2013Publication date: January 29, 2015Applicant: Dow Global Technologies LLCInventors: Matthias Sprehe, Oliver Petermann, Robert Bruce Appell
-
Patent number: 8816066Abstract: This invention provides cellulose ester interpolymers, and methods of oxidizing cellulose interpolymers and cellulose ester interpolymers. The invention also provides routes to access carboxylated cellulose ester derivatives with high acid numbers wherein the carboxyl group is attached directly to the cellulose backbone by a carbon-carbon bond. Through functionalization of an intermediate aldehyde, the corresponding cationic or zwitterionic cellulose ester derivatives can also be accessed. The interpolymers of the present invention have a number of end-use applications, for example, as binder resins in various types of coating compositions and as drug delivery agents.Type: GrantFiled: December 22, 2010Date of Patent: August 26, 2014Assignee: Eastman Chemical CompanyInventors: Charles Michael Buchanan, Norma Lindsey Buchanan, Susan Northrop Carty, Chung-Ming Kuo, Juanelle Little Lambert, Jessica Dee Posey-Dowty, Thelma Lee Watterson, Matthew Davie Wood, Michael Orlando Malcolm, Margaretha Soderqvist Lindblad
-
Publication number: 20140155589Abstract: The inhibitory fiber against virulence factors production of the present invention comprises a fiber and an inhibitor of virulence factors production fixed to the fiber by chemical bonding. The inhibitor of virulence factors production includes at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound. The production method of the present invention comprises: irradiating the fiber with an electron beam; and bringing into contact with the fiber at least one compound selected from the group consisting of a phosphate group-containing compound, a carboxylic acid group-containing compound, and a ketone group-containing compound to chemically bond the at least one compound to the fiber.Type: ApplicationFiled: July 25, 2012Publication date: June 5, 2014Applicants: KURASHIKI BOSEKI KABUSHIKI KAISHA, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATIONInventors: Kohji Miyazaki, Kunihiro Ohshima, Susumu Katsuen
-
Patent number: 8637322Abstract: The present invention relates to a method for labeling biological molecules of interest contained in a biological sample, consisting in: a) providing a reaction vessel, b) immobilizing capture molecules, which are capable of binding a label of the biological molecules of interest, on a solid support of the vessel, c) introducing the biological sample but also at least one label of the biological molecules of interest into said vessel and optionally any ingredient required for labeling or prelabeling the molecules of interest, d) incubating the vessel content and immobilizing the label which is not reacted with the molecules of interest by binding to the capture molecules, and e) using the labeled molecules of interest for subsequent steps. A method for treating a biological sample is also disclosed. Said invention is preferably used in a manual or automated method for purifying nucleic acids.Type: GrantFiled: May 31, 2006Date of Patent: January 28, 2014Assignee: BiomerieuxInventors: Eloy Bernal-Mendez, Ali Laayoun, Lionel Menou
-
Publication number: 20130267478Abstract: There is disclosed a cosmetic comprises a sugar compound obtained by reacting a hydroxyl group of a saccharide, an isocyanate group-containing organopolysiloxane represented by the following general formula (1), and an isocyanate group-containing organic compound represented by the following general formula (2). As a result, there is provided a cosmetic excellent in cosmetic sustainability and storage stability that can improve such undesirable feelings of use as insufficient spreadability and stickiness, improve the solubility to not only a non-polar oil such as a silicone oil and a light liquid paraffin, but also a polar oil such as a UV-absorber, an ester oil, and a natural animal and vegetable oil, provides non-stickiness with a cosmetic containing the polar oil, and prevent adhesion of the cosmetic to clothes (secondary adhesion).Type: ApplicationFiled: March 21, 2013Publication date: October 10, 2013Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventor: Masanao KAMEI
-
Publication number: 20130157992Abstract: The present invention relates to improved methods of making compositions and compositions made by these methods having improved stability and/or extended release of an active agent or drug upon administration. These compositions may generally comprise an active agent or drug non-covalently immobilized or bound to an excipient substrate. The active agent or drug may include a wide variety of drugs. Binding of the active agent or drug to the substrate may be achieved by evaporating a solvent containing the active agent dissolved therein or by triggering co-precipitation by addition of a precipitating solvent. Additional steps of vacuum removal of surrounding atmosphere and replacement with inert gas may provide additional stability. Present methods and compositions also facilitate manufacturing of drug products and may make these processes safer in some cases.Type: ApplicationFiled: December 20, 2012Publication date: June 20, 2013Inventor: Keith R. Latham
-
Publication number: 20120247768Abstract: Embodiments disclosed herein relate to gels for use in downhole applications containing the reaction product of at least one polymer, or polymer precursor, and at least one oxazoline crosslinking agent, wherein the at least one polymer, or polymer precursor, and the oxazoline crosslinking agent are normally combined in a solution, and methods including the use thereof.Type: ApplicationFiled: September 30, 2010Publication date: October 4, 2012Applicant: M-I DRILLING FLUIDS UK LIMITEDInventor: David Ballard
-
Publication number: 20120165516Abstract: A filler for optical isomer separation which: allows a polymer compound derivative to be immobilized on the surface of a carrier at a high ratio and is excellent in optical separation ability. The filler is characterized in that the filler is obtained by modifying part of the hydroxy or amino groups of a polymer compound having hydroxy or amino groups with molecules of a compound represented by the following general formula (I): A-X—Si(Y)nR3-n, and is carried by a carrier through chemical bonding.Type: ApplicationFiled: January 17, 2012Publication date: June 28, 2012Inventors: Yoshio OKAMOTO, Chiyo Yamamoto, Tomoyuki Ikai, Masami Kamigaito
-
Publication number: 20110098463Abstract: A cellulose derivative obtained from cellulose by substitution of hydrocarbyl groups ranging in carbon number from 1 to 7 and aliphatic acyl groups ranging in carbon number from 4 to 11 for at least part of the hydrogen atoms of hydroxyl groups contained in the cellulose. The cellulose derivative can exhibit good thermal plasticity, strength, heat resistance and mold working suitability.Type: ApplicationFiled: June 29, 2009Publication date: April 28, 2011Applicant: FUJIFILM CORPORATIONInventors: Toshihide Yoshitani, Yutaka Nozoe, Daisuke Sawai
-
Publication number: 20100311687Abstract: Non-crosslinked derivatives of oligo/polysaccharides of formula I, wherein: X is OH, OM, NH—R1, O—R1; M is an alkaline or alkaline-earth metal, transition metal, or cation containing a quaternary nitrogen atom; Y is H or R2; R1: the residue of an oligo/polysaccharide; R2: the residue of a C1-C4 linear chain aliphatic carboxylic acid or citric acid; provided that at least one X is NH—R1 or O—R1, while the other two X are present in acid (OH) or salified form (OM).Type: ApplicationFiled: December 18, 2007Publication date: December 9, 2010Inventors: Marco Bosco, Luca Stucchi, Fabrizio Picotti, Rita Gianni
-
Patent number: 7745645Abstract: Compounds having the general of formula I and/or formula II wherein R1 and R2 are the same or different and are independently selected from the group consisting of —H, —C1-C18-alkyl or -?-sulfoalkyl; X and Y are the same or different and are independently selected from the group consisting of —O?, —OH, —SH, —NH—NH2, —F, —Cl, —Br, —I, —O-Su (succinimidyl/sulfosuccinimidyl), —O-STP (4-sulfo-2,3,5,6-tetrafluorophenyl), —O-TFP (2,3,5,6-tetrafluorophenyl), —O-benzotriazole, -benzotriazole, —NR—CO—CH2—I, —NR2, —NR-biomolecule, —NR-L-COO?, —NR-L-COOH, —NR-L-COO-Su, —NR-L-COO-STP, —NR-L-COO-TFP, —NR-L-CONR2, —NR-L-CO-biomolecule, —NR-L-CO—NH—NH2, —NR-L-OH, —NR-L-O-phosphoramidite, —NR-L-CHO, —NR-L-maleimid, or —NR-L-NH—CO—CH2—I; where R is equal to R1 and R2 and L is selected from the group consisting of a divalent linear (—(CH2)o—, o=1 to 15), crossed, or cyclic alkane group that can be substituted by at least one atom selected from the group consisting of oxygen, substituted niType: GrantFiled: January 22, 2007Date of Patent: June 29, 2010Assignee: Pierce Biotechnology, Inc.Inventors: Wilhelm G. Frank, Matthias S. Wenzel, Peter T. Czerney, Surbhi Desai, Greg Hermanson
-
Patent number: 7662801Abstract: The present invention relates to the preparation of a series of oxidized cellulose esters suitable for use as a drug carrier in the development of biodegradable controlled and/or sustained release pharmaceutical, agricultural, and veterinary compositions, such as films, compacts, microspheres, and pellets. The esters are prepared by acylation of oxidized cellulose having at least 3% carboxyl groups. The resulting oxidized cellulose esters are soluble in aqueous alkaline solutions, water, and a variety of organic solvents.Type: GrantFiled: December 13, 2005Date of Patent: February 16, 2010Assignee: University of Iowa Research FoundationInventors: Vijay Kumar, Yang Dang
-
Patent number: 7649089Abstract: A new cellulose excipient, OCCAE, suitable for use as a binder, filler, and/or disintegrant in the development of solid dosage forms and as a bodying agent or a drug carrier in the preparation of topical formulations is described. The cellulose excipient is formed by reacting an oxidized cellulose ester with an alcohol in the presence of a catalyst. The invention also describes the formation of controlled release microspheres using OCCAE and/or oxidized cellulose esters that may be used to control the release of drug in a patient over a time period of several hours to several days.Type: GrantFiled: October 28, 2004Date of Patent: January 19, 2010Assignee: University of Iowa Research FoundationInventors: Vijay Kumar, Yang Dong
-
Patent number: 7595392Abstract: The present invention relates to the preparation of a series of oxidized cellulose esters suitable for use as a drug carrier in the development of biodegradable controlled and/or sustained release pharmaceutical, agricultural, and veterinary compositions, such as films, compacts, microspheres, and pellets. The esters are prepared by acylation of oxidized cellulose having at least 3% carboxyl groups. The resulting oxidized cellulose esters are soluble in aqueous alkaline solutions, water, and a variety of organic solvents.Type: GrantFiled: December 6, 2001Date of Patent: September 29, 2009Assignee: University of Iowa Research FoundationInventors: Vijay Kumar, Yang Dong
-
Publication number: 20090085260Abstract: A biodegradable aliphatic polyester, such as polylactic acid, is mixed with a monomer having allyl and molded into a molding having the crosslinking degree of the biodegradable aliphatic polyester increased. Thereafter, the molding is exposed to ionizing radiation to thereby obtain a molding excelling in heat resistance. Triallyl isocyanurate or triallyl cyanurate is used as the monomer having allyl.Type: ApplicationFiled: November 24, 2008Publication date: April 2, 2009Applicants: JAPAN ATOMIC ENERGY RESEARCH INSTITUTE, SUMITOMO ELECTRIC FINE POLYMER INCInventors: Naotsugu NAGASAWA, Toshiaki Yagi, Fumio Yoshii, Shin-ichi Kanazawa, Kiyoshi Kawano, Yoshihiro Nakatani, Hiroshi Mitomo
-
Patent number: 7485689Abstract: Disclosed are glucoside alkyl urethanes composed of units of the formula: A(O—CO—NH—R)3 wherein A represents a glucosyl unit of a starch hydrolysate molecule, the starch hydrolysate having a Dextrose Equivalent (D.E.) ranging from 1 to 47, (O—CO—NH—R) represents an N-alkyl aminocarbonyloxy group replacing a hydroxyl group of the glucosyl unit A, and wherein R represents a linear or branched, saturated or unsaturated alkyl group containing from 3 to 22 carbon atoms, and s represents the number of alkyl carbamate groups per glucosyl unit which number is expressed as degree of substitution (DS) with said DS value ranging from about 0.01 to about 2.0 which are useful as surface-active agents. Also disclosed are a method for their manufacture and compositions containing one or more glucoside alkyl urethanes. The glucoside alkyl urethanes have good to excellent tensio-active properties in combination with good biodegrability and they are suitable as surfactants for use in household and industrial applications, e.g.Type: GrantFiled: December 12, 2000Date of Patent: February 3, 2009Assignee: Tiense Suikerraffinaderij N.V.Inventors: Christian Victor Stevens, Alessia Meriggi, Karl Booten
-
Publication number: 20080255312Abstract: A polymer complex is disclosed which is the reaction product of one or more polymers having a terminal or pendant hydroxyl group, or a terminal or pendent carboxyl group, or combinations thereof, with at least one metal complex and one alkyl phosphate. This polymer complex acts as an adhesion promotion agent as well as a viscosity stabilizer when formulated in a printing ink or coating.Type: ApplicationFiled: November 16, 2004Publication date: October 16, 2008Applicant: Sun Chemical CorporationInventors: Mark Andreas Mielke, Mathew Charles Mathew, William P. Keaveney, Richard John Czarnecki, William Ford Wilson, Mark John Lindsey, Ralph Francis Arcurio
-
Patent number: 7301041Abstract: The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from —(CH2)n—O—, (CH2)—O—[(CH2)2—O]P— and —(CH2)q—CONH—(CH2)r—O—, or Y=—(CH2)S—NH— and Z=—(CH2)t—COO—, n=a whole number from 3 to 6 inclusive, p=a whole number from 1 to 4 inclusive, q=a whole number from 0 to 2 inclusive, r=a whole number from 0 to 2 inclusive, s=a whole number from 2 to 5 inclusive, t=a whole number from 3 to 6 inclusive, R and R?=H atoms or are protective groups used in oligonucleotide and peptide synthesis, where at least one of R or R? is protective group used in oligonucleotide and peptide synthesis and R and R? are as defined below: (i) when Z and Y are selected from (CH2)n—O—, —(CH2)—O—[(CH2)2—O]p— and —(CH2)q—CONH—(CH2)r—O—, then R and R? are protective groups used in oligonucleotide synthesis and R is a group which can leave a free OH group after deprotection, preferably a photolabile group such as monoType: GrantFiled: February 14, 2003Date of Patent: November 27, 2007Assignee: Bio MerieuxInventors: Carole Chaix-Bauvais, Corinne Moustrou, Aude-Emmanuelle Navarro, Hugues Brisset, Francis Garnier, Bernard Mandrand, Nicolas Spinelli
-
Publication number: 20070218218Abstract: A cellulose acylate film comprising a polymer derived from at least a monomer represented by Formula 1 and a cellulose acylate having an acyl group of 3 or more carbon atoms, wherein a total number of carbon atoms contained in the acyl groups in one it of the cellulose acylate is larger than 6.0 and not larger than 7.Type: ApplicationFiled: March 9, 2007Publication date: September 20, 2007Applicant: KONICA MINOLTA OPTO, INC.Inventors: Emiko Kataoka, Akihiko Takeda, Kazuaki Nakamura
-
Patent number: 7125991Abstract: The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or OCOR7, R3 represents an represents an alkyl radical. The invention also relates to a cosmetic composition comprising said compounds and to the use thereof to reduce and/or curb hair loss i.e.Type: GrantFiled: December 13, 2004Date of Patent: October 24, 2006Assignee: L'Oreal S.A.Inventors: Jean-Baptiste Galey, Maria Dalko, Lionel Breton
-
Patent number: 7026471Abstract: The present invention relates to a purification method of hydroxypropylmethyl cellulose phthalate, more particularly to a method of preparing high-purity hydroxypropylmethyl cellulose phthalate through a simple crushing process which comprises: increasing fluidity of reaction product mixture by adding fluidization solvent as a post-treatment process; and spraying it into water through a spray nozzle. As a result, formation of fine granular hydroxypropylmethyl cellulose phthalate particles prevents inter-particle coagulation during the a post-treatment process, and phthalic anhydride reactant, free phthalic acid and remaining acetic acid solvent can be removed effectively.Type: GrantFiled: April 2, 2002Date of Patent: April 11, 2006Assignee: Samsung Fine Chemicals Co., Ltd.Inventors: Kyu-Il Cho, Hyon-Ho Baek
-
Patent number: 6844003Abstract: The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 presents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or OCOR7, R3 represents an aryl or alkyl halogen, R4 represents an alkyl radical. The invention also relates to a cosmetic composition comprising said compounds and to the use thereof to reduce and/or curb hair loss i.e.Type: GrantFiled: April 4, 2003Date of Patent: January 18, 2005Assignee: L'OrealInventors: Jean-Baptiste Galey, Maria Dalko, Lionel Breton
-
Patent number: 6800754Abstract: A method for directly producing a mixture of cellulose sulfoacetate derivatives by esterification of cellulosic material, characterized in that it comprises the following steps i) the cellulosic material is suspended in a glacial acetic acid solution and the excess acetic acid is eliminated ii) the cellulosic acid that is swollen with acetic acid is suspended in a sulfuric acid solution in glacial acetic acid and iii) the cellulose material is made to react by adding acetic anhydride.Type: GrantFiled: March 4, 2002Date of Patent: October 5, 2004Assignee: Institut National de la Recherche Agronomique (INRA)Inventors: Gaelle Chauvelon, Luc Saulnier, Alain Buleon, Jean-Francois Thibault
-
Patent number: 6737524Abstract: Novel arylisothiocyanate compounds are described that are useful for activating alcohol-containing macromomolecules, for example polyethyleneglycols and cellulose, for covalent linkage to amino-groups of biomolecules, for example polypeptides such as antibodies, enzymes, and proteins.Type: GrantFiled: March 25, 2002Date of Patent: May 18, 2004Inventor: Paul K. Smith
-
Publication number: 20040034023Abstract: The invention concerns the use of aromatic compounds capable of binding with G-quadruplex structures to produce medicines with anti-telomerase effect. Said compounds correspond to formula (I) wherein: R1, R2 and R3, identical or different, represent a hydrogen atom, or a —CH2—NH—(CH2)n—X group, wherein n is an integer from 2 to 4, and X is selected among —NH2—, —N(CH3)2 radicals, a heterocyclic radical such as piperidyl, imidazolyl, morpholinyl radical, or an indole-type condensed heterocyclic radical, —Z represents CH or N, each compound comprising two nitrogen atoms in the Z positions. The invention is useful for producing anticancer medicines.Type: ApplicationFiled: July 15, 2003Publication date: February 19, 2004Inventors: Jean-Louis Mergny, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Pierre Vigneron, Jean-Marie Lehn, Claude Helene
-
Publication number: 20030187248Abstract: Novel arylisothiocyanate compounds are described that are useful for activating alcohol-containing macromolecules, for example polyethyleneglycols and cellulose, for covalent linkage to amino-groups of biomolecules, for example polypeptides such as antibodies, enzymes, and proteins.Type: ApplicationFiled: March 25, 2002Publication date: October 2, 2003Inventor: Paul K. Smith
-
Patent number: 6624298Abstract: Esterified polysaccharides and the process of making such products are disclosed. The process can be enzymatic where an enzyme is used as a catalyst for the reaction. The process can also be chemical where no enzyme is used. Novel Products are obtained through lipase-catalyzed &bgr;-lactone ring opening alcoholysis of ketene dimers and the process of making such compositions containing products.Type: GrantFiled: February 6, 2002Date of Patent: September 23, 2003Assignee: Hercules IncorporatedInventors: Huai N. Cheng, Qu Ming Gu
-
Publication number: 20020143160Abstract: 1.Type: ApplicationFiled: March 6, 2002Publication date: October 3, 2002Applicant: NOF CORPORATIONInventors: Junzo Sunamoto, Kazunari Akiyoshi, Ryuzo Hosotani, Akio Hayashi, Hiroki Fukui
-
Patent number: 6369214Abstract: Disclosed are a method of dispersing a pigment, a pigment dispersion, a coating composition comprising said pigment dispersion, an method of making a coating composition, and a method of improving the appearance of a coating composition. The pigment dispersion of the invention requires at least one pigment subjected to an action to decrease the average particle size of the pigment in the presence of an amine functional cellulose ester resin.Type: GrantFiled: September 30, 1999Date of Patent: April 9, 2002Assignee: BASF CorporationInventors: Anthony J. Tye, Gerald L. Bajc
-
Patent number: 6362330Abstract: The present invention relates to novel thermoplastic materials based on polysaccharide ethers which are simultaneously substituted by carboxylic acid ester groups and carbamate groups, together with mixtures of such derivatives with low molecular weight aliphatic urea derivatives.Type: GrantFiled: November 1, 1999Date of Patent: March 26, 2002Assignee: Wolff Wolsrode AGInventors: Joachim Simon, Hanns-Peter Müller, Dirk Jacques Dijkstra, Gunter Weber
-
Patent number: 6303315Abstract: A method for simultaneous release and detection of nucleic acids from complex biological samples is described. The invention relates to the combined use of lysis buffers containing strong chaotropic agents such as guanidine thiocyanate to facilitate cell lysis and release of cellular nucleic acids and to the use of a novel type of bicyclic nucleotide analogues, locked nucleic acid (LNA) to detect specific nucleic acids released during lysis by nucleic acid hybridisation. In particular methods are described for the covalent attachment of the catching LNA-oligo. Novel methods for sample preparation of e.g. polyadenylated mRNA species are also presented. The invention further addresses reagents for performing the methods as well as reagents and applications of the method.Type: GrantFiled: March 18, 2000Date of Patent: October 16, 2001Assignee: Exiqon A/SInventor: Jan Skouv
-
Patent number: 6242595Abstract: The present invention comprises a process for the recovery from a reaction mixture of cellulose carbamate produced by conversion of cellulose with excess urea in an inert organic liquid reaction carrier, wherein the reaction mixture is treated with added water under heat, then the liquid phase is separated as much as possible on a filter, the cellulose carbamate remaining on the filter is washed with water, optionally pre-dried and, if desired, dried and recovered, and the organic reaction carrier is recovered by phase separation from the combined liquids.Type: GrantFiled: June 2, 1998Date of Patent: June 5, 2001Assignee: Lurgi Zimmer AktiengesellschaftInventor: Gerhard Keunecke
-
Patent number: 6229007Abstract: Disclosed are amine functional cellulose ester resins and methods of making the same. The amine functional cellulose ester resins comprise at least one repeat unit of the structure: wherein R1, R2, and R3 are selected independently from the group consisting of hydrogen, R4C═O, and wherein at least one of R1, R2, and R3 is hydrogen, at least one of R1, R2, and R3 is R4C═O, and at least one of R1, R2, or R3 have the structure R4 is selected from the group consisting of C1-C20 alkyl groups, C1-C20 phenyl groups, C1-C20 napthyl groups, and C1-C20 alkenyl groups, L is a divalent linking group and R6 is selected from the group consisting of H and compounds having at least one secondary amine group, tertiary amine group, and mixtures thereof.Type: GrantFiled: September 30, 1999Date of Patent: May 8, 2001Assignee: BASF CorporationInventors: Anthony J. Tye, Gerald L. Bajc
-
Patent number: 6197950Abstract: Cationized hydroxyalkylcelluloses, which are highly compatible with surfactants, are represented by the following formula (I): wherein R1, R2 and R3 represent a hydrogen atom or a group represented by the formula CH2CH2OCH2CH (OH) CH2N+(CH3)Cl−, etc.; and “n” is a number of from 50 to 2,000; which have a mobility distribution (&Dgr;U) determined by electrophoresis ranging from 0.1×105 to 2.0×105 cm2/sec·V.Type: GrantFiled: February 8, 1999Date of Patent: March 6, 2001Assignee: Daicel Chemical Industries, Ltd.Inventors: Hiroyuki Nakamura, Shigenobu Sato
-
Patent number: 6184272Abstract: A fiber-reinforced molded plastic part, a process for its manufacture and a use. The fiber-reinforced molded plastic part consists of a plastic matrix with natural fibers particularly arranged in a uniformly distributed manner in the plastic matrix. The plastic matrix has at least two mutually mixed polymers, of which one is a biopolymer and the other is a polymer which is at least largely resistant to biological stress.Type: GrantFiled: February 12, 1998Date of Patent: February 6, 2001Assignee: DiamlerChrysler AGInventors: Thomas Foelster, Ralph Greiner, Dirk Schaefer
-
Patent number: 6133439Abstract: This invention provides cellulose ester fibers having an intermediate degree of substitution per anhydroglucose unit (DS/AGU) along with pigments which act as photooxidation catalyst. The fibers are useful as filler materials for tobacco products. The filter materials thus provided are easily dispersible and biodegradable and do not persist in the environment.Type: GrantFiled: May 14, 1999Date of Patent: October 17, 2000Assignee: Eastman Chemical CompanyInventors: Charles M. Buchanan, Robert M. Gardner, James E. Harris, Gether Irick, Jr., David V. Strickler, Jr.
-
Patent number: 6054545Abstract: A modified cellulose compound and a photopolymerizable resin composition containing the same are disclosed, the modified cellulose compound being obtained by reacting a hydroxyl group of cellulose or a cellulose derivative with an isocyanate group of a specific (meth)acryloyloxyalkylene isocyanate compound. The photopolymerizable resin composition has excellent adhesion to a substrate and high flexibility, and the modified cellulose compound has properties of easily decomposing and volatilizing even after baking.Type: GrantFiled: July 29, 1998Date of Patent: April 25, 2000Assignee: Tokyo Ohka Kogyo Co., Ltd.Inventors: Kiminori Oshio, Hiroyuki Obiya
-
Patent number: 5945547Abstract: The compound 2-deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate is described and claimed.Type: GrantFiled: March 19, 1997Date of Patent: August 31, 1999Assignee: Eli Lilly and CompanyInventors: Ta-Sen Chou, Perry C. Heath
-
Patent number: 5906926Abstract: A method for the manufacture of cellulose carbamate, whereby cellulose pulp is preliminarily activated by alkaline, hydrothermal and/or enzymatic treatment, then the activated cellulose pulp is mixed with aqueous urea solution, the water in the solution replaced with an organic reaction carrier, and thereafter the cellulose is reacted with urea in the liquid phase to yield cellulose carbamate, which is separated from the liquid medium and washed. The method results in uniform substitution and distribution of carbamate groups and in cellulose chain, which leads to good solubility of the cellulose carbamate in aqueous alkali solution as well as excellent spinnability for producing fibers, films, and other products.Type: GrantFiled: November 13, 1997Date of Patent: May 25, 1999Assignees: Zimmer Aktiengesellschaft, Instytut Wlokien ChemicznychInventors: Gerhard Keunecke, Henryk Struszczyk, Wlodzimierz Mikolajczyk, Pawel Starostka, Alojzy Urbanowski
-
Patent number: 5859217Abstract: Disclosed are a polymerizable sugar ester of the formula shown below and a process for the production thereof:S(OH).sub.q-1 --OOC--R--COOCH.dbd.CH.sub.2wherein S(OH).sub.q-1, represents a sugar residue obtained by removing one hydroxyl group from a sugar compound composed of a sugar skeleton S and q number of hydroxyl groups bonded thereto, and R represents an alkylene group. The polymerizable sugar ester is produced by reacting a sugar compound represented by the following general formula:S(OH).sub.qwherein S represents the sugar skeleton and q is the number of the hydroxyl groups bonded thereto, with a divinyl ester of an aliphatic dicarboxylic acid represented by the following general formula:CH.sub.2 .dbd.CHOOC--R--COOCH.dbd.CH.sub.2in the presence of a hydrolytic enzyme. The polymerizable sugar ester gives a sugar-based polymer by polymerization.Type: GrantFiled: July 3, 1996Date of Patent: January 12, 1999Assignees: Director-General of Agency of Industrial Science and Technology, Research Institute of Innovative Technology for the Earth, Toyo Boseki Kabushiki KaishaInventors: Yutaka Tokiwa, Shigeo Shibatani
-
Patent number: 5831076Abstract: The invention comprises a process for producing cellulose carbamate with improved solubility properties comprising converting cellulose with urea in an inert, liquid, organic reaction carrier, at reaction temperature in the range of 80.degree. to 180.degree. C. where the reaction temperature is increased as the reaction time increases.Type: GrantFiled: February 25, 1997Date of Patent: November 3, 1998Assignee: Zimmer AktiengesellschaftInventor: Gerhard Keunecke
-
Patent number: 5717087Abstract: The present invention relates to thermoplastic and biodegradable polysaccharide esters/polysaccharide ether esters, which are characterised in that they can be represented by the general structure ##STR1## wherein Polysaccharide-O represents the substituted OH groups of a polymeric saccharide unit and wherein A is a linear polyether chain of the following structureA=(E--O)nwherein E signifies a linear aliphatic or aromatic branched or unbranched chain having 2 to 11 C atoms, n is an integer equal to or greater than 0 and both B and D are a maleic acid addition product of the following structure ##STR2## wherein F is an aliphatic, saturated, monounsaturated or polyunsaturated carbon skeleton, which may optionally be provided with further substituents and wherein C can be a hydrogen atom, one or more substituents from the group dihydroxyethyl, hydroxypropyl, hydroxybutyl, methyl, ethyl, benzyl, dihydroxypropyl, carboxyalkyl, sulphoalkyl or cyanoethyl.Type: GrantFiled: August 2, 1996Date of Patent: February 10, 1998Assignee: Wolff Walsrode AGInventors: Jochen Kalbe, Reinhard Koch, Hanns Peter Muller, Jurgen Engelhardt, Wolfgang Koch, Volkhard Muller
-
Patent number: 5556773Abstract: A nested polymerase chain reaction (PCR) performed in a single reaction tube that remains closed after the reaction mixtures for each amplification have been introduced therein. The reaction mixture for the second PCR amplification is sequestered and preserved in an upper portion of the single, closed reaction tube during the first amplification, and subsequently introduced into the reaction space containing the end product of the first PCR amplification, without opening the reaction tube.Type: GrantFiled: August 18, 1994Date of Patent: September 17, 1996Inventor: Joseph Yourno
-
Patent number: 5552485Abstract: Fluoroaluminosilicate dental cement glasses are treated with an aqueous silanol treating solution and optionally with an additional organic compound. The treated glasses form cements with improved strength. The silanol can be ethylenically-unsaturated and can contain acidic groups, and, if so, is novel in its own right.Type: GrantFiled: June 2, 1995Date of Patent: September 3, 1996Assignee: Minnesota Mining and Manufacturing CompanyInventors: Sumita B. Mitra, Scott R. Culler, Bing Wang
-
Patent number: 5502178Abstract: A method is disclosed of preparing amidated water soluble cellulose acetates by amidating water soluble cellulose acetate. Methods are also provided for preparing aminated water soluble cellulose acetates of varying plasticities, film- and fiber-forming characteristics, and other properties by methanolysis of naturally-occurring chitin or by amination of water soluble cellulose acetate.Type: GrantFiled: August 20, 1993Date of Patent: March 26, 1996Assignee: Hoechst Celanese Corp.Inventor: Balarum Gupta
-
Patent number: 5488102Abstract: Compounds of formulae I and IaR--Y--CO--R.sub.3 --CO--O--A (I),R--Y--CO--R.sub.3 --CO--O--CH.sub.2 --A.sub.1 (Ia),whereinR is a radically polymerisable hydrocarbon group,R.sub.3 is a direct bond, linear or branched C.sub.1 -C.sub.22 alkylene, C.sub.3 -C.sub.8 cycloalkylene or C.sub.6 -C.sub.14 arylene,A is the radical, reduced by a hydroxy group in a 2- or 3position, of a cyclic-oligomeric carbohydrate or of a derivative of such a carbohydrate,A.sub.1 is the radical, reduced by a hydroxymethyl group, of a monomeric or linear oligomeric carbohydrate or of a derivative of such a carbohydrate, andY is --O--, --NH-- or --N(C.sub.1 -C.sub.6 alkyl)-.Homo- and co-polymers having those monomers have, depending upon their composition, hydrophilic, amphiphilic or hydrophobic properties and are able to form hydrogels. The polymers can be used, for example, as surfactants, thickeners, carriers for biologically active ingredients or in the manufacture of contact lenses.Type: GrantFiled: July 26, 1994Date of Patent: January 30, 1996Assignee: Ciba Geigy CorporationInventor: Dirk Vetter
-
Patent number: RE38484Abstract: Cationized hydroxyalkylcelluloses, which are highly compatible with surfactants, are represented by the following formula (I): wherein R1, R2 and R3 represent a hydrogen atom or a group represented by the formula CH2CH2OCH2CH (OH) CH2N+(CH3)Cl−, etc.; and “n” is a number of from 50 to 2,000; which have a mobility distribution (&Dgr;U) determined by electrophoresis ranging from 0.1×105 10−5 to 2.0×105 10−5 cm2sec·V.Type: GrantFiled: April 11, 2002Date of Patent: March 30, 2004Assignee: Daicel Chemical Industries, Ltd.Inventors: Hiroyuki Nakamura, Shigenobu Sato