Flavon Sugar Compounds Patents (Class 536/8)
  • Patent number: 4414207
    Abstract: Rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: February 22, 1982
    Date of Patent: November 8, 1983
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4393055
    Abstract: Hydroxyalkyl ether derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: May 3, 1982
    Date of Patent: July 12, 1983
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Seymour Bernstein
  • Patent number: 4353889
    Abstract: Analogs of the glycoside rebaudioside A are disclosed. These materials have the formula ##STR1## wherein R is a simple physiologically acceptable noncarbohydrate polar organic group. The analogs are sweet and find use as sweeteners.
    Type: Grant
    Filed: June 11, 1981
    Date of Patent: October 12, 1982
    Assignee: Dynapol
    Inventor: Grant E. DuBois
  • Patent number: 4352792
    Abstract: Antiviral compositions containing 3-alkoxyflavone compounds as their active ingredients are disclosed.
    Type: Grant
    Filed: April 7, 1980
    Date of Patent: October 5, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hideo Ishitsuka, Haruyoshi Shirai, Isao Umeda, Yasuji Suhara
  • Patent number: 4342753
    Abstract: Carboxyalkyl derivatives of rutin polyl(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: August 3, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, John F. Poletto, Seymour Bernstein
  • Patent number: 4342752
    Abstract: Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: August 3, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, John F. Poletto, Seymour Bernstein
  • Patent number: 4334058
    Abstract: Rutin poly(H--)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: June 8, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Patent number: 4313880
    Abstract: The invention concerns a process for producing apigenin, wherein it is extracted with a water/ethanol mixture from ligules of Matricaria Chamomilla L. and after purified by crystallization from ethanol.Concerned is also the use of the pure product apigenin in human spasmolytic therapy.
    Type: Grant
    Filed: November 27, 1979
    Date of Patent: February 2, 1982
    Assignee: Benomelli S.p.A.
    Inventor: Claudio Redaelli
  • Patent number: 4297348
    Abstract: Therapeutic compositions for the treatment of acne which comprise from about 0.1% to about 5% by weight naringin, from about 0.1% to about 10% by weight naringenin, from about 0.05% to about 5% by weight of an antimicrobially active partially hydrolyzed naringin, from about 0.01% to about 5% weight colloidal silica, and from about 80% to 97% by weight of a solvent.
    Type: Grant
    Filed: April 11, 1980
    Date of Patent: October 27, 1981
    Assignee: Rush-Hampton Industries, Inc.
    Inventor: Stephen E. Frazier
  • Patent number: 4255563
    Abstract: A process for preparing anthocyans by reducing the corresponding flavonoid glycosides with a metal and acid at temperatures not higher than 30.degree. C. under acidic conditions, precipitating the anthocyans formed from the reduction reaction as a metal salt by neutralizing the reaction solution with an alkali and isolating the free anthocyans by decomposing the metal salt with concentrated hydrochloric acid.
    Type: Grant
    Filed: February 2, 1979
    Date of Patent: March 10, 1981
    Assignee: Shiraimatsu Shinyaku Company, Ltd.
    Inventors: Kazuo Wakihira, Satoshi Kikumoto, Hiroshi Kigawa, Osamu Nozaki, Michio Minami
  • Patent number: 4238483
    Abstract: A process for the production of antimicrobial compositions from naturally occurring flavanoid glycosides. Flavanoid glycosides are acid hydrolyzed under substantially quiescent condition at a temperature within the range of about 60.degree. C. and about 100.degree. C. for a sufficient time to hydrolyze the flavanoid glycoside to partially hydrolyzed flavanoid compositions having antimicrobial activity.
    Type: Grant
    Filed: July 19, 1979
    Date of Patent: December 9, 1980
    Inventor: Stephen E. Frazier
  • Patent number: 4229439
    Abstract: This invention is concerned with a new method of treatment for reducing retention of cholesterol, e.g., in the treatment of atheroma and angiopathies which comprises administering to a patient in need of such treatment, a therapeutically effective amount of at least one anthocyanidin compound of the general formula ##STR1## wherein R represents a glycosyl group such as glycosyl or rhamnoglucosyl; R' represents H, OH or OCH.sub.3 ; and X.sup.- is a non-toxic anion such as chloride, citrate, tartrate, phosphate or malate.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: October 21, 1980
    Assignee: Societe de Recherches Industrielles (SORI)
    Inventor: Bernard Majoie
  • Patent number: 4211772
    Abstract: Acetals and ketals of benzopyran glycosides, prepared by condensing a benzopyran glycoside with a carbonyl compound using a chloroformate ester as condensing agent, show enhanced activity in treating capillary fragility and related pathologies, as well as effectiveness in modifying the evolution of diabetic cataracts.
    Type: Grant
    Filed: June 1, 1978
    Date of Patent: July 8, 1980
    Assignee: Laboratoires Sarget
    Inventors: Francois Fauran, Claude Feniou, Jacqueline Mosser, Annie Thibault, Claude Andre, Gisele Prat
  • Patent number: 4171430
    Abstract: Glycosides such as stevioside, glycyrrhizin and neohesperidin dihydrochalcone are separated from non-glycosides such as phyllodulcin and perillartine by column chromatography using a porous gel.
    Type: Grant
    Filed: August 26, 1977
    Date of Patent: October 16, 1979
    Assignee: Toyo Soda Manufacturing Co., Ltd.
    Inventors: Susumu Matsushita, Tetsuo Ikushige
  • Patent number: 4153788
    Abstract: A process is provided for preparing mono-O-.beta.-hydroxyethyl-7-rutoside of the formula: ##STR1## which comprises contacting rutoside of the formula: ##STR2## in a solvent which is an at least partially aqueous medium with a boric acid alkali salt in an amount substantially not exceeding the amount necessary to form a boron complex of formula: reacting said boron complex with ethylene oxide to form a hydroxyethoxy compound of the formula ##STR3## and treating said hydroxyethoxy compound in an at least partially aqueous acid medium, whereby there is produced said mono-O-.beta.-hydroxyethyl-7-rutoside.
    Type: Grant
    Filed: March 7, 1977
    Date of Patent: May 8, 1979
    Assignee: ZYMA S.A.
    Inventors: Pierre Courbat, Alban Albert
  • Patent number: 4095000
    Abstract: Foodstuff and fodder additives are made by linking essential aminoacids to carbohydrates or other assimilable polyhydroxy compounds in such a way that the aminoacid is liberated in the digestive tract.
    Type: Grant
    Filed: May 16, 1975
    Date of Patent: June 13, 1978
    Assignee: Max Brenner
    Inventor: Max Brenner
  • Patent number: 4087558
    Abstract: The use of neohesperidin chalcone as a substitute for sugar.
    Type: Grant
    Filed: March 16, 1976
    Date of Patent: May 2, 1978
    Inventors: Harald A. B. Linke, Douglas E. Eveleigh
  • Patent number: 4078137
    Abstract: A process for manufacturing pure diosmin suitable as a therapeutic agent comprising acetylating hesperidin, observing by means of ultraviolet absorption the progress of the acetylation reaction and continuing such reaction until there disappears the band initially occurring at a wave length in the range of 264 to 280 nm and there appears in place thereof a new maximum at a wave length of about 330 nm. Thereafter the acetylation product is brominated, the obtained bromination product hydrolyzed and the obtained product after precipitation isolated, in order to obtain diosmin having a bromine content less than 0.1%.
    Type: Grant
    Filed: May 6, 1976
    Date of Patent: March 7, 1978
    Assignee: Hommel Aktiengesellschaft
    Inventors: Christian Schmid, Max Glasbrenner, Jean Heusser
  • Patent number: 3988435
    Abstract: Dihydrochalcone glucosides are reacted with certain quaternary ammonium compounds to give the corresponding quaternary ammonium derivatives. These new derivatives have a sweet taste and are bactericidal in nature: they can be used in oral products such as dentifrice.
    Type: Grant
    Filed: January 9, 1974
    Date of Patent: October 26, 1976
    Assignee: Lever Brothers Company
    Inventors: Francoise Ernestine Lucie Humbert, Robert Dedieu
  • Patent number: 3984394
    Abstract: New compounds which are monobasic metal salts of dihydrochalcones and the method of their preparation, the monosodium, monopotassium, and monocalcium salts being useful as sugar substitutes and sweetening agents for foods and beverages.
    Type: Grant
    Filed: May 14, 1971
    Date of Patent: October 5, 1976
    Assignee: Nutrilite Products, Inc.
    Inventors: Edward B. Westall, Alan W. Messing