Hetero Ring Patents (Class 544/209)
  • Patent number: 5696261
    Abstract: Novel piperidine-triazine compounds of the formula (Ia) and (Ib) suitable for use as light stabilisers, heat stabilisers and oxidation stabilisers for organic materials. The meanings of R.sub.1, R.sub.2, R.sub.3, G.sub.1, G.sub.2, L.sub.1, L.sub.2, m and n are defined in the text.
    Type: Grant
    Filed: November 8, 1995
    Date of Patent: December 9, 1997
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Valerio Borzatta, Graziano Vignali, Fabrizio Guizzardi
  • Patent number: 5693808
    Abstract: Di-, tri- and tetrachromophoric perylene-3,4:9,10-tetracarboxylic acid imides of the formula I ##STR1## in which A is, for example, 1,4-phenylene,R is 1-hexylheptyl andm is 2,are readily accessible by reaction of a perylene-3,4:9,10-tetracarboxylic acid monoanhydride monoimide with 1,4-diaminobenzene-bisformamide. The preparation process and also a specific process for the preparation of monochromic perylene-3,4:9, 10-tetracarboxylic acid bisimides are also claimed. These processes are particularly suitable for reaction of highly electron-rich aromatic amines, which cannot be reacted under conventional condensation conditions.
    Type: Grant
    Filed: November 6, 1995
    Date of Patent: December 2, 1997
    Assignee: Ciba Specialty Chemicals Corporation
    Inventor: Heinz Langhals
  • Patent number: 5686390
    Abstract: An iminosulfonylurea compound or a salt thereof which is useful as a herbicide and growth control agent against weeds.
    Type: Grant
    Filed: December 15, 1995
    Date of Patent: November 11, 1997
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Kenzi Makino, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
  • Patent number: 5686623
    Abstract: A method for preparing taxane derivatives of general formula (I) by esterifying protected baccatin III or protected 10-deacetyl baccatin III with an acid of general formula (II). In general formulae (I) and (II), Ar is an aryl radical; R.sub.1 and R.sub.2 which are the same or different, are a hydrogen atom, an alkyl, phenylalkyl, phenyl, alkoxyphenyl or dialkoxyphenyl radical, or R.sub.1 or R.sub.2, together with the carbon atom to which they are attached, form a 4-7 membered ring; R.sub.3 is an acetyl radical or a hydroxy function protective grouping, and R.sub.4 is a hydroxy function protective grouping; R is a phenyl radical or a radical of formula R.sub.5 --O-- wherein R.sub.5 -- is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl or saturated or unsaturated nitrogenous heterocylcyl radical. The products of general formula (I) are particularly useful for preparing taxol, Taxotere and analogues thereof having remarkable antitumor properties.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: November 11, 1997
    Assignee: Rhone-Poulenc Rorer, S.A.
    Inventors: Jean-Noel Denis, Andrew-Elliot Greene, Alice Kanazawa
  • Patent number: 5683964
    Abstract: An N-(substituted amino)imide derivative represented by the formula (I) is a novel compound which can be utilized as an effective ingredient of herbicidal compositions. ##STR1## wherein, R.sup.1 is hydrogen atom, C.sub.1 -C.sub.4 alkyl group, C.sub.7 -C.sub.9 aralkyl group, C.sub.1 -C.sub.4 haloalkyl group, (C.sub.1 -C.sub.4 alkyl)carbonyl group or (C.sub.1 -C.sub.4 alkyl)sulfonyl group;A represents a structure selected from the group consisting of the following formulas (A-1), (A-2), (A-3), (A-4) and (A-5) ##STR2## wherein R.sup.2 and R.sup.3 in the formula (A-1) are independently hydrogen atom or C.sub.1 -C.sub.4 alkyl group, but not R.sup.2 =R.sup.3 =H, R.sup.4 in the formula (A-4) is halogen atom, C.sub.1 -C.sub.4 alkyl group and/or nitro group, m is an integer of 0-4, the substituents of m not less than 2 being same or different;X.sup.1 and X.sup.2 are independently hydrogen atom, halogen atom, C.sub.1 -C.sub.4 alkyl group, C.sub.1 -C.sub.4 alkoxy group, C.sub.1 -C.sub.4 alkylthio group, C.sub.1 -C.sub.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: November 4, 1997
    Assignee: Kureha Kagaku Kogyo K.K.
    Inventors: Yoichi Kanda, Hideo Arabori, Masato Arahira, Tsutomu Sato
  • Patent number: 5679794
    Abstract: Compounds possessing both a hindered amine moiety, such as a derivative of 2,2,6,6-tetramethylpiperidine, and a hydroxylamine moiety where the N-hydroxy group is not attached to a nitrogen atom in a piperidine ring are valuable stabilizers for protecting polymer compositions against the deleterious effects of actinic light and from the adverse effects of high temperature polymer processing environments.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 21, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Joseph Suhadolnik, Ramanathan Ravichandran, Valerio Borzatta, Graziano Vignali
  • Patent number: 5670452
    Abstract: The present invention provides an indazolesulfonylurea derivative represented by the general formula: ##STR1## wherein R.sup.1 is a hydrogen atom or an alkyl group, etc., R.sup.2 and R.sup.3 are the same or different and represent a hydrogen atom, a halogen atom, an alkyl group, the formula --COR.sup.4 (wherein R.sup.4 represents an alkoxy group, etc.), an alkoxy group, a haloalkoxy group or a cyano group, etc., X is an oxygen atom or a sulfur atom, Y is a hydrogen atom or an alkyl group, etc., A and B are the same or different and represent a halogen atom, an alkoxy group or an alkyl group, etc., and Z represents a nitrogen atom or a methine group, as well as a herbicide containing it as an active ingredient and an intermediate for its production.The compound of the present invention exhibits excellent herbicidal effects over a wide range from the preemergence stage to the growing stage of various weeds which are problematic in agricultural fields.
    Type: Grant
    Filed: April 9, 1996
    Date of Patent: September 23, 1997
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Chiharu Suzuki, Katsumi Masuda, Masatoshi Tamaru, Masahito Inamori, Nobuo Takefuji, Katsutada Yanagisawa, Yasunori Ogawa
  • Patent number: 5656760
    Abstract: The present invention provides a compound having the formula: ##STR1## in which M is hydrogen, sodium, potassium, calcium, magnesium, ammonium, mono-, di-, tri- or tetra-C.sub.1 -C.sub.4 alkylammonium, mono-, di- or tri-C.sub.1 -C.sub.4 hydroxyalkylammonium or ammonium that is di- or tri-substituted by a mixture of C.sub.1 -C.sub.4 alkyl and C.sub.1 -C.sub.4 hydroxyalkyl groups; R.sub.1 is a group having the formula: ##STR2## in which M has its previous significance and n is 1 or 2; and R.sub.2 is O--C.sub.1 -C.sub.12 alkyl or N(R.sub.3)(R.sub.4) in which R.sub.3 and R.sub.4, independently, are hydrogen, C.sub.1 -C.sub.12 alkyl or C.sub.1 -C.sub.4 hydroxyalkyl, or R.sub.3 and R.sub.4, together with the nitrogen atom, are the atoms required to form a pyrrolidine, piperidine or morpholine group.
    Type: Grant
    Filed: September 20, 1995
    Date of Patent: August 12, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Jean-Pierre Bacher, Claude Eckhardt, Dieter Reinehr
  • Patent number: 5652364
    Abstract: Novel process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines, based on the reaction of cyanuric chloride with C.sub.1 -C.sub.4 alkanols or with sodium or potassium C.sub.1 -C.sub.4 alkoxides and subsequent reaction with 2,2,6,6-tetramethyl-4-piperidinols in the presence of a transesterification catalyst.The various reactions can be carried out in the same reactor, without isolation of the intermediates.
    Type: Grant
    Filed: August 10, 1995
    Date of Patent: July 29, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Graziano Vignali, Fabrizio Guizzardi, Graziano Zagnoni, Roberto Scrima
  • Patent number: 5633378
    Abstract: Polyalkylpiperidine compounds of the formula I ##STR1## in which Y is the group ##STR2## are very effective stabilizers for organic materials.
    Type: Grant
    Filed: June 29, 1995
    Date of Patent: May 27, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Karl Gaa, Matthias Z ah, Josef Wiedemann
  • Patent number: 5604178
    Abstract: This invention is to provide an N-(substituted amino)pyrrole derivative represented by the formula (I): which is used as an effective ingredient of herbicidal compositions: ##STR1## wherein R.sup.2, R.sup.3, R.sup.4 and R.sup.5 is independently hydrogen atom, halogen atom, C.sub.1 -C.sub.4 alkyl group, (C.sub.1 -C.sub.4 alkyl)carbonyl group, (C.sub.3 -C.sub.6 cycloalkyl) carbonyl group, (C.sub.1 -C.sub.4 haloalkyl)carbonyl group, (C.sub.3 -C.sub.5 alkenyl)carbonyl group, benzoyl group which may be substituted with 1-3 halogen atoms and/or C.sub.1 -C.sub.4 alkyl groups, N,N-[(di-C.sub.1 -C.sub.4 alkyl)amino]carbonyl group, (C.sub.1 -C.sub.4 alkoxy)carbonyl group, etc., X.sup.1 and X.sup.2 are independently hydrogen atom, halogen atom, C.sub.1 -C.sub.4 alkyl group, C.sub.1 -C.sub.4 alkoxy group, etc., and Z is nitrogen atom or CH.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: February 18, 1997
    Assignee: Kureha Kagaku Kogyo K.K.
    Inventors: Yoichi Kanda, Hideo Arabori, Masato Arahira, Tsutomu Sato
  • Patent number: 5604179
    Abstract: An iminosulfonylurea derivative of the formula (1) or its salt ##STR1## wherein Q is ##STR2## wherein the variables are herein below defined, and a herbicidal and and growth control method.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Kenzi Makino, Shigeaki Akiyama, Hideaki Suzuki, Takeshi Nagaoka, Toshio Niki, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe, Kimihiro Ishikawa
  • Patent number: 5576440
    Abstract: Compounds of formula (I), where R.sup.1, R.sup.2, n, W, R.sup.3 and A are as defined in claim 1, are suitable for use as herbicides and plant growth regulators. They can be produced by a process similar to known processes. To produce them, new compounds of formula (II) are reacted with a carbamate of formula R*--O--CO--NR.sup.3 A, where R.sup.3 stands for phenyl or alkyl. The compounds of formula (II) can be obtained from the corresponding sulphochlorides.
    Type: Grant
    Filed: January 4, 1995
    Date of Patent: November 19, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Kehne, Lothar Willms, Oswald Ort, Klaus Bauer, Hermann Bieringer
  • Patent number: 5574037
    Abstract: This invention concerns novel compounds of the formula I: ##STR1## in which P is a group of formula II or a group of formula III; R.sup.1 is alkyl, cycloalkyl, cycloalkylalkyl, phenyl or phenylalkyl; R.sup.2 is hydrogen, alkyl, amino or alkylamino; R.sup.3 and R.sup.4 are independently hydrogen, alkyl, phenyl or benzyl; R.sup.6 is alkyl, amino or alkylamino; C and D are independently ethylene or trimethylene; Z is a direct bond between C and D, or an oxy, thio, carbonyl, methylene, ethylenedioxymethylene, ethylidene, or isopropylidene link, or Z is a group of the formula .dbd.N.R.sup.5 in which R.sup.5 is alkyl, phenyl or benzyl; R8 is hydrogen, cycloalkylalkyl, alkyl, alkenyl, alkynyl or phenylalkyl; or R8 is a alkylene or alkenylene linked to the nitrogen atom of the group Q.A.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 12, 1996
    Assignee: Imperial Chemical Industries PLC
    Inventors: Stuart D. Mills, Rodney B. Hargreaves, Bernard J. McLoughlin
  • Patent number: 5571915
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 5, 1996
    Assignee: Cytec Technology Corp.
    Inventor: Ram B. Gupta
  • Patent number: 5563127
    Abstract: Novel boronic acid and ester and carboxyl-modified amino acid compounds of the Formula I, which are inhibitors of trypsin-like enzymes, are disclosed :R.sup.1 --Z--CHR.sup.2 --A,where R.sup.1, Z, R.sup.2 and A are defined within.
    Type: Grant
    Filed: December 27, 1994
    Date of Patent: October 8, 1996
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Eugene C. Amparo, William H. Miller, Gregory J. Pacofsky, John Wityak, Patricia C. Weber, John J. V. Duncia, Joseph B. Santella, III
  • Patent number: 5550234
    Abstract: Polyalkylpiperidine compounds of the formula I ##STR1## in which Y is one of the groups ##STR2## are distinguished by very low volatility at elevated temperature and are very effective stabilizers for organic substances.
    Type: Grant
    Filed: June 29, 1995
    Date of Patent: August 27, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Karl Gaa, Matthias Z ah
  • Patent number: 5529976
    Abstract: Compounds of formula (I), where R.sup.1, R.sup.2, n, W, R.sup.3 and A are as defined in claim 1, are suitable for use as herbicides and plant growth regulators. They can be produced by a process similar to known processes. To produce them, new compounds of formula (II) are reacted with a carbamate of formula R.sup.* --O--CO--NR.sup.3 A, where R.sup.3 stands for phenyl or alkyl. The compounds of formula (II) can be obtained from the corresponding sulphochlorides.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: June 25, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz Kehne, Lothar Willms, Oswald Ort, Klaus Bauer, Hermann Bieringer
  • Patent number: 5512535
    Abstract: This invention relates to herbicidal pyridinesulfonylureas which are highly active as preemergence and postemergence herbicides.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: April 30, 1996
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Paul Hsiao-Tseng Liang
  • Patent number: 5502189
    Abstract: Compounds which comprise at least one group of the formula I or II ##STR1## and at least one polyalkylpiperidine group of the formula III ##STR2## in which R and R.sub.1 to R.sub.6 have the meaning indicated in claim 1, are effective stabilisers for organic materials against damage by light, oxygen and heat.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: March 26, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Mario Slongo, Jean-Luc Birbaum, Jean Rody, Andreas Valet
  • Patent number: 5493022
    Abstract: Salts of organic optical brighteners or light stabilizers with compounds which contain at least one ammonium, cycloammonium or immonium group and at least one aliphatic group, cycloaliphatic group, or aromatic group bonded to at least one (up to four) carbonyl group, or heteroaromatic group. resp. basic brighteners or light stabilizers with compounds which contain a radical containing at least one carboxylic acid or sulphonic acid radical and one aliphatic, cycloaliphatic, monomeric aromatic or heteroaromatic group, or contain a C.sub.2-14 -dicarboxylic acid or amino-C.sub.2-1 -alkylcarboxylic acid radical, are eminently suitable for the brightening and light stabilizing of synthetic plastic compositions.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: February 20, 1996
    Assignee: Sandoz Ltd.
    Inventors: Bansi L. Kaul, Angelos-Elie Vougioukas
  • Patent number: 5489683
    Abstract: Novel piperidine-triazine compounds of the formula (Ia) and (Ib) suitable for use as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials. The meanings of R.sub.1, R.sub.2, R.sub.3, G.sub.1, G.sub.2, L.sub.1, L.sub.2, m and n are defined in the text.
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: February 6, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Valerio Borzatta, Graziano Vignali, Fabrizio Guizzardi
  • Patent number: 5472933
    Abstract: This invention relates to certain herbicidal pyrrolesulfonylureas, compositions thereof and a method for their use as herbicides or plant growth regulants.
    Type: Grant
    Filed: February 24, 1993
    Date of Patent: December 5, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William T. Zimmerman, Bruce A. Lockett, John Cuomo
  • Patent number: 5470921
    Abstract: A synthetic polyamide of formula I and its salts ##STR1## in which each R.sub.1 independently is selected from hydrogen, carboxyl, amino or a group of formula .alpha.-A.sub.1 -R.sub.10 (.alpha.)where A, is a bridging group and R.sub.10 is a sterically hindered amine group;each R.sub.2 independently is hydrogen or a group of formula .alpha.A is a bridging group of the formula ##STR2## is 0 or 1; R.sub.3 is hydrogen, C.sub.1-12 alkyl or is a significance of R.sub.10 ;R.sub.5 is hydrogen or C.sub.1-12 alkylR.sub.4 is a significance of R.sub.10 or a group of formula .alpha.; andp is an integer from 5 to 200;with the proviso that the compound of formula I contains 1-400 sterically hindered amine groups.
    Type: Grant
    Filed: May 20, 1994
    Date of Patent: November 28, 1995
    Assignee: Sandoz Ltd.
    Inventors: Bansi L. Kaul, Angelos-Elie Vougioukas, Jurgen Goldmann
  • Patent number: 5461024
    Abstract: A novel thiophenesulfonylurea derivative having herbicidal activity, having the formula (I): ##STR1## wherein the substituents are herein described.
    Type: Grant
    Filed: December 9, 1993
    Date of Patent: October 24, 1995
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Dae-Whang Kim, Dong Ju Jeon, Sang Soon Park, Jae Chun Woo, Tae Jun Kim
  • Patent number: 5457199
    Abstract: The present invention relates to novel piperidine compounds of the formula (I) ##STR1## in which X.sub.1, X.sub.2, X.sub.3 and n are as defined in the text. The compounds of the invention can be used as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials, in particular synthetic polymers.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: October 10, 1995
    Assignee: Ciba-Geigy Corporation
    Inventors: Roberto Scrima, Graziano Zagnoni
  • Patent number: 5449776
    Abstract: Novel piperidine compounds of the formula (I) are suitable for use as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials.The definitions of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, A and n in the formula (I) are given in the text.
    Type: Grant
    Filed: May 25, 1994
    Date of Patent: September 12, 1995
    Assignee: Ciba-Geigy Corporation
    Inventors: Graziano Vignali, Fabrizio Guizzardi, Graziano Zagnoni
  • Patent number: 5449777
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 and R.sub.2 are each independently of the other hydrogen, C.sub.1 -C.sub.24 alkyl, phenyl-substituted C.sub.1 -C.sub.4 alkyl, unsubstituted or C.sub.1 -C.sub.4 alkyl-substituted C.sub.5 -C.sub.8 cycloalkyl, unsubstituted or C.sub.1 -C.sub.4 alkyl-substituted phenyl, with the proviso that both substituents R.sub.1 and R.sub.2 are not simultaneously hydrogen,n is an integer from 3 to 8,R.sub.3 is C.sub.1 -C.sub.18 alkyl, C.sub.2 -C.sub.8 alkyl which is interrupted by --O--, --S-- or --NR.sub.4 --, unsubstituted or C.sub.1 -C.sub.4 alkyl-substituted C.sub.5 -C.sub.8 cycloalkyl, phenyl-substituted C.sub.1 -C.sub.4 alkyl, unsubstituted or C.sub.1 -C.sub.12 alkyl-substituted phenyl or a radical --(CH.sub.2).sub.m --COOR.sub.4 or ##STR2## R.sub.4 is C.sub.1 -C.sub.18 alkyl, unsubstituted or C.sub.1 -C.sub.4 alkyl-substituted C.sub.5 -C.sub.8 cycloalkyl, benzyl or phenyl,R.sub.5 is hydrogen, methyl, benzyl or a radical --OR.sub.7,m is 1 or 2,X is O, S, or NR.sub.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: September 12, 1995
    Assignee: Ciba-Geigy Corporation
    Inventor: Rita Pitteloud
  • Patent number: 5446144
    Abstract: A compound of formula (I): ##STR1## wherein: R.sup.1 is hydrogen, alkyl, alkoxyalkyl, carboxylic acyl or phenylalkyl, or an optionally substituted tetramethylpiperidyl group: R.sup.2 is hydrogen, alkyl, carboxylic acyl or phenylalkyl group; R.sup.3 is alkylene optionally interrupted by at least one oxygen atom X is oxygen or --NR.sup.5 --; wherein R.sup.5 is hydrogen or alkyl,: Y is --OCO--, --COO--, --CONH-- or --OCONH--; n is 2 to 4; and, when n is 2, Z is alkylene optionally interrupted by at least one oxygen, sulfur or aryl, cycloalkyl or heterocyclic group, or, when n is 3, Z is alkanetriyl in which a carbon is optionally replaced by nitrogen or, when n is 4, Z is alkanetetrayl optionally interrupted by at least one oxygen atom and acid addition salts thereof are valuable polymer stabilizers.
    Type: Grant
    Filed: February 2, 1990
    Date of Patent: August 29, 1995
    Assignee: Sankyo Company, Limited
    Inventors: Toshimasa Toda, Satoru Naito, Hisayu Osawa, Takaaki Yamazaki
  • Patent number: 5430006
    Abstract: Herbicidal substituted thienylsulphonylureas of the formula ##STR1## in which R.sup.1 represents ethyl or n-propyl,R.sup.2 represents hydrogen or methyl,X and Y are identical or different and each represent hydrogen, hydroxyl, amino, cyano, halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.1 -C.sub.4 -halogenoalkyl, C.sub.1 -C.sub.4 -alkoxy-C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -halogenoalkoxy, C.sub.1 -C.sub.4 -alkoxy-C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, C.sub.1 -C.sub.4 -alkylamino or di-(C.sub.1 -C.sub.4 -alkyl)-amino andZ represents nitrogen, a CH group or a C-halogen group,and their salts.
    Type: Grant
    Filed: September 21, 1993
    Date of Patent: July 4, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ernst R. F. Gesing, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt
  • Patent number: 5420274
    Abstract: An improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines wherein cyanuric chloride is reacted in successive steps with two appropriate alkylamines and an alkyl mercaptan is described where the improvement involves use of a single water-immiscible solvent and a phase transfer catalyst in the mercaptan addition step.
    Type: Grant
    Filed: October 19, 1993
    Date of Patent: May 30, 1995
    Assignee: Ciba-Geigy Corporation
    Inventors: Henry C. Grace, Mervin G. Wood, Jr.
  • Patent number: 5405959
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: November 10, 1993
    Date of Patent: April 11, 1995
    Assignee: Cytec Technology Corp.
    Inventor: Ram B. Gupta
  • Patent number: 5387682
    Abstract: Radiation-sensitive organo-halogen compounds having a photo-labile halomethyl-1,3,5-triazine moiety and at least one polymerizable moiety within one molecule. The compounds of this invention have at least one halomethyl substituent attached to a carbon atom of the triazine moiety and at least one polymerizable monomeric moiety attached to another atom of the triazine moiety. The compounds of this invention can be used to prepare polymers having 1,3,5-triazine substituents attached thereto. The compounds of this invention are good photoinitiators, and compositions containing them can be used in printing, duplicating, copying, and other imaging systems. The compounds of this invention are capable of stimulation by actinic radiation at a wavelength of about 250 to 900 nanometers to generate free radicals.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: February 7, 1995
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: James A. Bonham, Mithcell A. Rossman, Richard J. Grant
  • Patent number: 5356894
    Abstract: R.sup.1 is hydrogen, (1-6C)alkyl, or (1-4C)alkanoyl;R.sup.2 (when not as hereinbelow defined together with X) is (1-6C)alkyl substituted by a group of formula R.sup.10 Xb(CO).sub.m in which m is 0 or 1, provided that when m is 0, X and Xb are separated by at least two carbon atoms, Xb is an imino group of formula --NRb in which Rb together with R.sup.10 and the adjacent nitrogen atom forms a morpholino, thiomorpholino, piperidino or azetidino ring;and X is oxy, thio, sulphinyl, sulphonyl or an imino group of formula --NRa-- in which Ra is hydrogen, (1-6C)alkyl or together with R2 and the adjacent nitrogen atom forms a morpholino, thiomorpholino, piperidino or azetidino ring; andA is N or CT in which T is hydrogen or (1-4C)alkyl;or a pharmaceutically acceptable salt thereof; processes for the manufacture of the compounds and pharmaceutical compositions containing them. The compounds are useful as adenosine antagonists.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: October 18, 1994
    Inventors: Peter W. Rodney, Geraint Jones, Michael G. Collis, Simon M. Poucher
  • Patent number: 5342927
    Abstract: Reactive dyestuffs of the formula ##STR1## in which X is ##STR2## and Z is a heterocyclic reactive group and the remaining groups have the meaning given in the description, are highly suitable for the dyeing and printing of hydroxyl- or amido-containing materials.
    Type: Grant
    Filed: July 21, 1992
    Date of Patent: August 30, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfram Reddig, Karl-Josef Herd
  • Patent number: 5340928
    Abstract: Reactive dyestuffs of the formula (1) ##STR1## in which D denotes the radical of an organic dyestuff,R, R.sub.1 and R.sub.2, independently of one another, denote hydrogen or substituted or unsubstituted C.sub.1-4 -alkyl,A denotes a substituted or unsubstituted aliphatic, aromatic or aromatic-aliphatic bridging member,X denotes Cl, FPym denotes the radicals ##STR2## n denotes 1 or 2, are suitable in particular for the dyeing of cellulose fibres.
    Type: Grant
    Filed: May 6, 1992
    Date of Patent: August 23, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Hoppe, Karl-Josef Herd, Thomas Eizenhofer, Wolfgang Harms, Hermann Henk, Klaus Kunde, Wolfram Reddig
  • Patent number: 5336706
    Abstract: The present invention relates to novel piperidine-triazine compounds of the formula (I) ##STR1## in which R.sub.1 is e.g. hydrogen or methyl, A.sub.1 is e.g. >N--CH.sub.3, R.sub.2 is e.g. --(CH.sub. 2).sub.2-6 --, R.sub.3 is e.g. 2,2,6,6-tetramethyl-4-piperidyl or 1,2,2,6,6-pentamethyl-4-piperidyl, or --A.sub.1 --R.sub.2 -- is a direct bond and, in this case, R.sub.3 is e.g. a group ##STR2## is a group of the formula (IVa) or (IVc) ##STR3## q and m are e.g. zero, X.sub.1 is e.g. a group of the formula (Va)--A.sub.4 --R.sub.9 --A.sub.5 -- (Va)in which A.sub.4 and A.sub.5 which are identical or different are e.g. an >N--R.sub.8 group where R.sub.8 is e.g. hydrogen, 2,2,6,6-tetramethyl-4-piperidyl or 1,2,2,6,6-pentamethyl-4-piperidyl, R.sub.9 is e.g. --(CH.sub.2).sub.2-6 --, n is e.g. a number from 1 to 10, Y.sub.1 is e.g. OH, ONa, OK or a group --X.sub.1 Z with Z being hydrogen or methyl and Y.sub.2 is e.g. hydrogen or methyl.
    Type: Grant
    Filed: September 29, 1993
    Date of Patent: August 9, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Valerio Borzatta, Roberto Scrima, Graziano Vignali
  • Patent number: 5336622
    Abstract: A fluorescence polarization immunoassay for flecainide and tracers therefor are disclosed.
    Type: Grant
    Filed: April 11, 1989
    Date of Patent: August 9, 1994
    Assignee: Abbott Laboratories
    Inventor: Daniel F. Heiman
  • Patent number: 5332737
    Abstract: This invention concerns novel compounds of the formula I: ##STR1## in which P is a group of formula II or a group of formula III; R.sup.1 is alkyl, cycloalkyl, cycloalkylalkyl, phenyl or phenylalkyl; R.sup.2 is hydrogen, alkyl, amino or alkylamino; R.sup.3 and R.sup.4 are independently hydrogen, alkyl, phenyl or benzyl; R.sup.6 is alkyl amino or alkylamino; C and D are independently ethylene or trimethylene; Z is a direct bond between C and D, or an oxy, thio, carbonyl, methylene, ethylenedioxymethylene, ethylidene, or isopropylidene link, or Z is a group of the formula .dbd.N.R.sup.5 in which R.sup.5 is alkyl, phenyl or benzyl; R8 is hydrogen, cycloalkylalkyl, alkyl, alkenyl, alkynyl or phenylalkyl; or R8 is a alkylene or alkenylene linked to the nitrogen atom of the group Q.A.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: July 26, 1994
    Assignee: Imperial Chemical Industries PLC
    Inventors: Stuart D. Mills, Rodney B. Hargreaves, Bernard J. McLoughlin
  • Patent number: 5332816
    Abstract: The present invention relates to novel piperazine-piperidine compounds of the general formula (I) ##STR1## in which R.sub.1 is e.g. hydrogen or methyl, R.sub.2 is e.g. ethylene, m is zero or 1 and n is e.g. 1, and when n is 1, A is e.g. 2,2-dimethyl-1-propanoyl, n-butoxycarbonyl, n-tetradecyloxycarbonyl or 2,4-bis[N-butyl-(2',2',6',6'-pentamethyl-4'-piperidyl)amino]triazin-6-yl.The said compounds are effective as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials.
    Type: Grant
    Filed: July 19, 1990
    Date of Patent: July 26, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Graziano Vignali, Valerio Borzatta
  • Patent number: 5332813
    Abstract: Difluorotriazinyl compounds of the formula ##STR1## are continuously reacted in a reactor with amines in solution or suspension.
    Type: Grant
    Filed: November 3, 1992
    Date of Patent: July 26, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Hoppe, Wolfgang Mullers, Hans-Georg Frosch, Richard Sommer, Siegbert Arnold, Wolfram Reddig
  • Patent number: 5326869
    Abstract: A process for the preparation of a 5,7-diaryloxy-2-(2-heteroaryl)-triazolo[1,5-a][1,3,5]triazine, which comprises reacting a N-2-(4,6-diaryloxy)-[1,3,5]triazinyl-N'-(2-heteroarylcarbonyl)hydrazine with a polyphosphoric acid silyl ester. The invention also provides a multistep process for preparing certain triazolotriazines having activity asadenosine antagonists.
    Type: Grant
    Filed: November 20, 1992
    Date of Patent: July 5, 1994
    Assignee: Imperial Chemical Industries, PLC
    Inventor: Jonathan Hutton
  • Patent number: 5324834
    Abstract: The present invention relates to novel co-oligomers containing recurring units of the formulae (Ia) and (Ib) ##STR1## which have a number average molecular weight of e.g. from 1,000 to 5,000 and a (Ia):(Ib) ratio of e.g. 1:1, and in which R.sub.1 and R.sub.5 are e.g. N-(2,2,6,6-tetramethyl-4-piperidyl)-n-butylamino, R.sub.2 is e.g. 2,2,6,6-tetramethyl-4-piperidyl, R.sub.3 is e.g. hexamethylene, R.sub.4 is e.g. hydrogen and X is e.g. a group ##STR2## These compounds are particularly suitable for stabilizing organic materials against light, heat and oxidation.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: June 28, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Valerio Borzatta, Primo Carrozza
  • Patent number: 5312917
    Abstract: Water-soluble triazine derivatives of formula (1) are disclosed. The novel compounds are representatives of sterically hindered amines (HALS stabilisers) and are suitable for enhancing the thermal and photochemical stability of undyed and dyed polyamide fibre materials.
    Type: Grant
    Filed: December 9, 1992
    Date of Patent: May 17, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Francesco Fuso, Gerhard Reinert
  • Patent number: 5310907
    Abstract: Amelinic compounds of general formula (I) ##STR1## obtained by subsequent condensation reaction of 1 mol of a cyanuric acid halide with 1 mol of amine and of a polyamine and by hydrolysis reaction of the thus obtained intermediate. Compounds of general formula (I) are used, in particular, as antiflame additives.
    Type: Grant
    Filed: September 9, 1991
    Date of Patent: May 10, 1994
    Assignee: Ministero Dell`Universita` e Della Ricerca Scientifica e Tecnologica
    Inventors: Roberto Cipolli, Gilberto Nucida, Enrico Masarati, Roberto Oriani, Mario Pirozzi
  • Patent number: 5304646
    Abstract: Amelinic compounds of general formula (I) ##STR1## obtained by condensation of 1 mol of cyanuric acid halide with 2 mols of an amine and subsequent hydrolysis of the intermediate thus obtained. Compounds of general formula (I) are used, in particular, as flame retardant additives for polymers.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: April 19, 1994
    Assignee: Ministero Dell'Universita' E Della Ricerca Scientifica E Tecnologica
    Inventors: Roberto Cipolli, Gilberto Nucida, Enrico Masarati, Roberto Oriani, Mario Pirozzi
  • Patent number: 5300502
    Abstract: Phenoxyalkyl-substituted heteroaromatics of the general formulae Ia and Ib ##STR1## where A is an unsubstituted or substituted heteroaromatic radical having 6 5 ring members and 1, 2 or 3 nitrogen atoms in the ring, R.sup.1 is hydrogen, halogen or C.sub.1 -C.sub.3 -alkyl. R.sup.2 is hydrogen or C.sub.1 -C.sub.4 -alkyl. Q.sub.a is an unsubstituted or substituted azole radical and Q.sub.b is a substituted or unsubstituted heteroaromatic radical which has a five-membered ring,and their use for combating pests.
    Type: Grant
    Filed: July 8, 1993
    Date of Patent: April 5, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Leyendecker, Hans-Juergen Neubauer, Uwe Kardorff, Christoph Kuenast, Peter Hofmeister, Wolfgang Krieg
  • Patent number: 5298480
    Abstract: The invention embraces compounds of formula ##STR1## and salts thereof, wherein: X and Y are independently selected from various optionally substituted alkoxy, alkenyloxy, alkynyoxy and phenoxy groups;W is oxygen or sulfur;R.sub.1 is hydrogen or alkyl;E is CH or N;R.sub.2 and R.sub.3 are independently selected from various halo, alkyl, alkoxy and amino substituents.The compounds of the invention show herbicidal properties particularly for the control of broad leaf plants in grass crops such as wheat. In further embodiments the invention provides processes for the preparation of compounds I, intermediates useful in the preparation of compounds of formula I, compositions containing as active ingredient a compound of formula I and herbicidal and plant growth regulating processes utilizing compounds of formula I.
    Type: Grant
    Filed: May 17, 1991
    Date of Patent: March 29, 1994
    Assignee: ICI Australia Operations Proprietary Limited
    Inventors: Keith Watson, Wayne Best
  • Patent number: 5294709
    Abstract: Methine compounds represented by the following general formula (Ia) or (Ib); ##STR1## wherein CYA represents atoms having a cyanine chromogen structure, MER represents atoms having a merocyanine chromogen structure, L represents a divalent linkage group composed of an atom or atoms containing at least one of a carbon atom, a nitrogen atom, a sulfur atom and an oxygen atom, Het represents a group containing a 5- to 7-membered hetero ring containing at least one nitrogen atom, l.sub.1 represents 1 or 2, l.sub.2 represents 0 or 1, and l.sub.3 represents 1, 2 or 3. Methine dyes using same are also disclosed.
    Type: Grant
    Filed: January 14, 1993
    Date of Patent: March 15, 1994
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Toshinao Ukai, Yoshio Inagaki
  • Patent number: 5290776
    Abstract: A compound of the formula I ##STR1## wherein: R.sup.1 is hydrogen, (1-6C)alkyl, or (1-4C)alkanoyl;R.sup.2 is phenyl, a C-linked aromatic 5- or 6-membered heterocyclic ring containing one of oxygen and sulphur and/or one or two nitrogen, or (1-8C)alkyl, alkenyl or alkynyl unsubstituted or substituted by a phenyl or a C-linked aromatic 5- or 6-membered heterocylic ring containing one of oxygen and sulphur and/or one or two nitrogen, any phenyl being unsubstituted or substituted by one, two or three of (1-4C)alkyl, (1-4C)alkoxy, halogen, trifluoromethyl, hydroxy, benzyloxy and (1-5C)alkanoyloxy;A is N or CT in which T is hydrogen or (1-4C)alkyl;or a pharmaceutically acceptable salt thereof, processes for the manufacture of the compounds, and pharmaceutical compositions containing them. The compounds are useful as adenosine antagonists.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: March 1, 1994
    Assignee: Imperial Chemical Industries, PLC
    Inventors: Peter W. R. Caulkett, Geraint Jones, Michael G. Collis, Simon M. Poucher