Two Carbocyclic Rings Bonded Directly To The Same Ring Atom Of The Lactone Ring Patents (Class 549/308)
  • Patent number: 7915430
    Abstract: A method of producing a phenolphthalein comprises reacting a phenolic compound of the formula: wherein R1 is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of a heterogeneous catalyst and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each R1 is independently a hydrogen or a C1-C12 hydrocarbyl group, and R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the heterogeneous catalyst comprises a metal oxide composition in combination with a porous support, wherein the metal is molybdenum, tungsten, or a combination comprising at least one of the foregoing metals.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: March 29, 2011
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventors: Venkata Rama Narayanan Ganapathy Bhotla, Shivappa Basappa Halligudi, Gurram Kishan, Salkod Parameshwar Mallika, Bhaskar Veldurthy
  • Patent number: 7868190
    Abstract: A method for producing a phenolphthalein compound comprises: reacting a phenolic compound of the formula: wherein R1 is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of a heterogeneous catalyst and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each R1 is independently a hydrogen or a C1-C12 hydrocarbyl group; and R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the heterogeneous catalyst comprises, on a porous support, a calcination product of a heteropolyacid composition.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: January 11, 2011
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventors: Venkata Rama Narayanan Ganapathy Bhotla, Shivappa Basappa Halligudi, Gurram Kishan, Salkod Parameshwar Mallika, Bhaskar Veldurthy
  • Patent number: 7838689
    Abstract: A method for producing a phenolphthalein compound is disclosed, comprising: reacting a phenolic compound of the formula: wherein Ra is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein Rb is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of an ionic liquid catalyst composition and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each Ra is independently a hydrogen or a C1-C12 hydrocarbyl group, and Rb is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the ionic liquid catalyst composition comprises a combination of an ionic liquid and a metal halide wherein the metal is selected from the group consisting of a Group IIB, IIIA, VIII, or IVA metal, and a combination thereof.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: November 23, 2010
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventors: Venkata Rama Narayanan Ganapathy Bhotla, Dwairath Dhar, Gurram Kishan, Salkod Parameshwar Mallika
  • Patent number: 7709663
    Abstract: Boron chelate complexes of the general formula are described, where X is either —C(R1R2)— or —C(R1R2)—C(?O)—, in which R1, R2 independently of one another denote H, alkyl (with 1 to 5 C atoms), aryl, silyl or a polymer, and one of the alkyl radicals R1 or R2 may be bonded to a further chelatoborate radical, or X denotes 1,2-aryl with up to two substituents S in the positions 3 to 6 in which S1, S2 independently of one another denote alkyl (with 1 to 5 C atoms), fluorine or a polymer, as well as M+ denotes Li+, Na+, K+, Rb+, Cs+ or [(R3R4R5R6)N]+ or H+, where R3, R4, R5, R6 independently of one another denote H or alkyl with preferably 1 to 4 C atoms.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: May 4, 2010
    Assignee: Chemetall GmbH
    Inventors: Ulrich Wietelmann, Uwe Lischka, Klaus Schade, Jan-Christoph Panitz
  • Publication number: 20100081831
    Abstract: A method for producing a phenolphthalein compound is disclosed, comprising: reacting a phenolic compound of the formula: wherein Ra is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein Rb is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of an ionic liquid catalyst composition and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each Ra is independently a hydrogen or a C1-C12 hydrocarbyl group, and Rb is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the ionic liquid catalyst composition comprises a combination of an ionic liquid and a metal halide wherein the metal is selected from the group consisting of a Group IIB, IIIA, VIII, or IVA metal, and a combination thereof
    Type: Application
    Filed: September 29, 2008
    Publication date: April 1, 2010
    Inventors: Venkata Rama Narayanan Ganapathy BHOTLA, Dwairath DHAR, Gurram KISHAN, Salkod Parameshwar MALLIKA
  • Publication number: 20100081828
    Abstract: A method of producing a phenolphthalein comprises reacting a phenolic compound of the formula: wherein R1 is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of a heterogeneous catalyst and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each R1 is independently a hydrogen or a C1-C12 hydrocarbyl group, and R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the heterogeneous catalyst comprises a metal oxide composition in combination with a porous support, wherein the metal is molybdenum, tungsten, or a combination comprising at least one of the foregoing metals.
    Type: Application
    Filed: September 29, 2008
    Publication date: April 1, 2010
    Inventors: Venkata Rama Narayanan Ganapathy BHOTLA, Shivappa Basappa HALLIGUDI, Gurram KISHAN, Salkod Parameshwar MALLIKA, Bhaskar VELDURTHY
  • Publication number: 20100081829
    Abstract: A method for producing a phenolphthalein compound comprises: reacting a phenolic compound of the formula: wherein R1 is a hydrogen or a C1-C12 hydrocarbyl group, with a phthalic anhydride compound of the formula: wherein R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen, in the presence of a heterogeneous catalyst and a promoter to form a reaction mixture comprising a phenolphthalein compound of the formula: wherein each R1 is independently a hydrogen or a C1-C12 hydrocarbyl group; and R2 is a hydrogen, a C1-C12 hydrocarbyl group, or a halogen; wherein the heterogeneous catalyst comprises, on a porous support, a calcination product of a heteropolyacid composition.
    Type: Application
    Filed: September 29, 2008
    Publication date: April 1, 2010
    Inventors: Venkata Rama Narayanan Ganapathy BHOTLA, Shivappa Basappa HALLIGUDI, Gurram KISHAN, Salkod Parameshwar MALLIKA, Bhaskar VELDURTHY
  • Patent number: 7683187
    Abstract: The present invention relates to a process for preparing a lactone. The process comprises the steps of reacting an aldehyde with an organic halide in a carbon chain extension reaction to form an alcohol compound comprising a functional group capable of allowing for carbonylation of said alcohol compound, and then reacting said alcohol compound in a carbonylation reaction to form an hydroxycarboxylic acid; and cyclizing the hydroxycarboxylic acid to produce the lactone.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: March 23, 2010
    Assignee: Danisco A/S
    Inventors: Lars Wiebe, Thomas Schmidt
  • Patent number: 7408016
    Abstract: A composition comprising a polycarbonate, wherein the polycarbonate has a weight average molecular weight of greater than 15,000, comprises more than 15 mole percent structural units derived from a 2-aryl-3,3-bis(4-hydroxyaryl)phthalimide: wherein R1 is selected from the group consisting of aryl groups having 6 to 25 carbon atoms and aralkyl groups having 7 to 25 carbon atoms, and R2 is selected from the group consisting of a hydrogen, a hydrocarbyl group, and a halogen; and further wherein the polycarbonate has a yellowness index of less than 10 as measured on a 3 millimeter thick plaque in accordance with ASTM D1925 is disclosed.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: August 5, 2008
    Assignee: SABIC Innovative Plastics IP B.V.
    Inventors: Gautam Chatterjee, Anantharaman Dhanabalan, Katherine Glasgow, Vinod Kumar Rai, Suresh Shanmugam, Veeraraghavan Srinivasan
  • Publication number: 20080177091
    Abstract: A phthalic anhydride, a phenol, a catalyst, and a promoter are reacted to form a reaction mixture comprising phenolphthalein. The reaction mixture is treated with a first solvent system to form a slurry. The first solvent system comprises a first polar organic solvent. In some embodiments the first solvent system additionally comprises a non-polar organic solvent. Use of the solvent system to treat the reaction mixture simplifies subsequent purification.
    Type: Application
    Filed: January 24, 2007
    Publication date: July 24, 2008
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Rajshekhar Madhukar Basale, Balakrishnan Ganesan, Ashok S Shyadligeri, Veeraraghavan Srinivasan
  • Patent number: 7214823
    Abstract: Described are tri-, tetra-, and penta-metal complex salts of hydroxycitric acid, compositions containing the same, and methods of making the same, where the salt comprises at least three different metals selected from zinc, magnesium, sodium, potassium, and calcium.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: May 8, 2007
    Assignee: Indfrag Limited
    Inventors: Philip Samuel, Somasundaram Saravanan, Meyyappan Thangaraj
  • Patent number: 7135577
    Abstract: Disclosed herein is a method for producing a 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine. The method comprises forming a reaction mixture comprising at least one substituted or unsubstituted phenolphthalein compound, at least one substituted or unsubstituted primary hydrocarbyl amine, and an acid catalyst; and heating the reaction mixture to form 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine. An adduct of the 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine is formed either by using an excess of the primary hydrocarbyl amine in the first heating step, or by isolating crude 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine after the heating step and then reacting with a further amount of the primary hydrocarbyl amine. The 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine has a formula: where R1 is selected from the group consisting of a hydrogen and a hydrocarbyl group, and R2 is selected from the group consisting of a hydrogen, a hydrocarbyl group, and a halogen.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: November 14, 2006
    Assignee: General Electric Company
    Inventors: Vinod Kumar Rai, Radhakrishna Srinivasarao Arakali
  • Patent number: 6872839
    Abstract: Benzofuran-2-ones, compositions comprising benzofuranones, processes for preparing them, and their use as colorants for high or low molecular mass organic material.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: March 29, 2005
    Assignee: Cibaspecialty Chemicals Corp.
    Inventors: Leonhard Feiler, Thomas Ruch, Olof Wallquist, Peter Nesvadba
  • Patent number: 6479704
    Abstract: The present invention relates to an improved for the hydrogenation of an immiscible mixture of an organic reactant in water. The immiscible mixture can result from the generation of water by the hydrogenation reaction itself or, by the addition of, water to the reactant prior to contact with the catalyst. The improvement resides in effecting the hydrogenation reaction in a monolith catalytic reactor from 100 to 800 cpi, at a superficial velocity of from 0.1 to 2 m/second in the absence of a cosolvent for the immiscible mixture. In a preferred embodiment, the hydrogenation is carried out using a monolith support which has a polymer network/carbon coating onto which a transition metal is deposited.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: November 12, 2002
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Andrew Francis Nordquist, Frederick Carl Wilhelm, Francis Joseph Waller, Reinaldo Mario Machado
  • Publication number: 20020019545
    Abstract: Lactone compounds of formula (1) are useful as monomers to form base resins for use in chemically amplified resist compositions adapted for micropatterning lithography.
    Type: Application
    Filed: May 31, 2001
    Publication date: February 14, 2002
    Applicant: Shin-Etsu Chemical Co., Ltd.
    Inventors: Takeshi Kinsho, Koji Hasegawa, Takeru Watanabe, Tsunehiro Nishi, Mutsuo Nakashima, Seiichiro Tachibana, Jun Hatakeyama
  • Patent number: 5997891
    Abstract: This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: December 7, 1999
    Assignee: IPA, LLC
    Inventors: Ronnie S. Fuerst, Richard Melker, Christopher D. Batich
  • Patent number: 5886196
    Abstract: Hydrogen bis(oxalato)borate of the formula ##STR1## is used as a protonic acid catalyst in condensation reactions, such as Friedel-Crafts condensations, vinyl ether condensations of acetals with vinyl or propenyl ethers and acylations of phenols. The products of such condensations are, for example, dihydro-vitamin K.sub.1 monobenzoate, d,l-.alpha.-tocopherol, various intermediates in the synthesis of carotenoids as well as d,l-.alpha.-tocopherol acetate. As a result of the use in accordance with the invention of hydrogen bis(oxalato)borate various disadvantages associated with the use of other protonic acid catalysts, e.g. problems with corrosion, toxicity and environmental contamination, are avoided. The novel catalyst has advantages with respect to selectivity, yields, amounts required as well as working up after completion of the respective condensation.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: March 23, 1999
    Assignee: Roche Vitamins Inc.
    Inventor: Claude Furbringer
  • Patent number: 5837645
    Abstract: This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: November 17, 1998
    Inventors: Ronnie S. Fuerst, Richard Melker, Christopher D. Batich
  • Patent number: 5532029
    Abstract: This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.
    Type: Grant
    Filed: February 14, 1995
    Date of Patent: July 2, 1996
    Inventors: Ronnie S. Fuerst, Richard Melker, Christopher D. Batich
  • Patent number: 5231195
    Abstract: Phenolphthaleinic bis(acrylate), phenolphthaleinic bis(methacrylate), and phenolphthaleinic (acrylate) (methacrylate) may be polymerized to form polymerizates especially useful for lenses and lens blanks.
    Type: Grant
    Filed: November 18, 1992
    Date of Patent: July 27, 1993
    Assignee: PPG Industries, Inc.
    Inventors: Vaikunth S. Prabhu, Charles R. Coleman
  • Patent number: 5210232
    Abstract: Pyran-containing phthalides of the formula ##STR1## in which R is hydrogen, alkyl which has not more than 12 carbon atoms and is unsubstituted or substituted by halogen, cyano, hydroxyl or lower alkoxy, or is cycloalkyl, phenalkyl or phenyl each of which is unsubstituted or substituted, or an unsubstituted or substituted heterocyclic radical, R' is hydrogen, or R together with R' is C.sub.2 -C.sub.3 alkylene which is unsubstituted or substituted by methyl,X is hydrogen, alkyl having 1 to 12 carbon atoms or a monocyclic or polycyclic aromatic or heteroaromatic radical and the ring A is a benzene or naphthalene ring which is unsubstituted or monosubstituted or polysubstituted by halogen, lower alkyl, lower alkoxy or lower alkoxycarbonyl, and the ring B is an aromatic or heteroaromatic radical which has 6 ring atoms and which can contain an aromatic fused ring, it being possible for both the ring B and the fused ring to be substituted.
    Type: Grant
    Filed: January 2, 1992
    Date of Patent: May 11, 1993
    Assignee: Ciba-Geigy Corporation
    Inventor: Rox Phaff
  • Patent number: 5011967
    Abstract: Bischloroformate oligomer compositions are prepared by passing phosgene into a heterogeneous aqueous-organic mixture containing at least one dihydroxyaromatic compound, with simultaneous introduction of a base at a rate to maintain a specific pH range and to produce a specific volume ratio of aqueous to organic phase. By this method, it is possible to employ a minimum amount of phosgene. The reaction may be conducted batchwise or continuously. The bischloroformate composition may be employed for the preparation of cyclic polycarbonate oligomers or linear polycarbonate, and linear polycarbonate formation may be integrated with bischloroformate composition formation in a batch or continuous process.
    Type: Grant
    Filed: December 4, 1987
    Date of Patent: April 30, 1991
    Assignee: General Electric Company
    Inventors: James M. Silva, Robert A. Pyles
  • Patent number: 4904810
    Abstract: Aqueous bischloroformates are prepared by the reaction of a dihydroxyaromatic compound (e.g., bisphenol A) with phosgene in a substantially inert organic liquid (e.g., methylene chloride) and in the presence of an aqueous alkali metal or alkaline earth metal base, at a pH below about 8. After all solid dihydroxyaromatic compound has been consumed, the pH is raised to a higher value in the range of about 7-12, preferably 9-11, and maintained in said range until a major proportion of the unreacted phosgene has been hydrolyzed. At the same time, any monochloroformate in the product may be converted to bischloroformate.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: February 27, 1990
    Assignee: General Electric Company
    Inventors: Daniel J. Brunelle, Thomas G. Shannon
  • Patent number: 4855460
    Abstract: A process for the preparation of perfluoroalkylated ketones and/or perfluoroalkylated alcohols, comprising the step of contacting a perfluoroalkyl iodide or perfluoroalkyl bromide with an acid anhydride, in the presence of a metal chosen from zinc and cadmium.
    Type: Grant
    Filed: July 11, 1988
    Date of Patent: August 8, 1989
    Assignee: Rhone-Poulenc Chimie
    Inventors: Marc Tordeux, Claude Wakselman, Catherine Francese
  • Patent number: 4732991
    Abstract: Process comprises the combination of the three steps of condensing 3-N(R).sub.2 -4-X-benzoic acid with an aromatic or heterocyclic aldehyde, Y-CHO, under acidic conditions to produce 3-Y-5-X-6-N(R).sub.2 phthalide (II), condensing said phthalide with a compound of the formula Z-H under alkaline or acid conditions to produce 2-(.alpha.-Y-.alpha.-Z)methyl-4-X-5-N(R).sub.2 benzoic acid (III), and oxidizing said benzoic acid to produce 3-Y-3-Z-5-X-6-N(R).sub.2 phthalide (I) where: R is hydrogen, non-tertiary alkyl of one to four carbon atoms, benzyl or substituted benzyl; X is hydrogen or halo; Y is 4-R.sup.1 -3-R.sup.2 -2-R.sup.1 -phenyl, 1-R.sup.5 -2-R.sup.6 -5/6-R.sup.4 -3-indolyl, 9-R.sup.7 -3-carbazolyl, 9-julolidinyl, 3,4-dioxymethylenephenyl, 2-thienyl, 1-R.sup.8 -2-pyrrolyl, or 4-pyridinyl; and Z is 4-R.sup.1 -3-R.sup.2 -2-R.sup.1 -phenyl, 1-R.sup.5 -2-R.sup.6 -5/6-R.sup.4 -3-indolyl or 1-R.sup.
    Type: Grant
    Filed: February 18, 1986
    Date of Patent: March 22, 1988
    Assignee: Hilton Davis Chemical Co.
    Inventors: Paul J. Schmidt, Nathan N. Crounse
  • Patent number: 4695648
    Abstract: A compound having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrognase (PGDH) and having the formula ##STR1## in which R.sub.1 and R.sub.2 are hydrogen or lower alkyl;R.sub.3 is hydrogen, lower alkyl or substituted or unsubstituted phenyl;R.sub.4, R.sub.5, and R.sub.6 are hydrogen, halogen, lower alkyl, lower alkoxy, cyano, carboxy or nitro; at least one of the groups R.sub.4 to R.sub.6 being hydrogen;R.sub.7 to R.sub.11 are hydrogen, halogen, cyano, lower alkyl, trifluoromethyl, lower alkoxy, hydroxy, lower acyl, lower alkoxycarbonyl, N,N,-diloweralkyl-aminocarbonyl or N,N-loweralkylene-aminocarbonyl; and R.sub.8 and R.sub.10 may in addition be carboxy; at least two of R.sub.7 to R.sub.11 always being hydrogen; and--A-- is --CO--, --CH.sub.2 --CO--, --CH.dbd.CH--, --CH.dbd.CH--CO-- or corresponding groups in which a hydrogen atom is replaced by a lower alkyl group.The invention comprises also lactones of those compounds in which R.sub.
    Type: Grant
    Filed: August 29, 1985
    Date of Patent: September 22, 1987
    Assignee: Pharmacia AB
    Inventors: Karl H. Agback, Tamara Agback, Alf S. Nygren
  • Patent number: 4588744
    Abstract: There is disclosed a method and composition of matter for treating mammalian inflammatory viral infections, acne, dermatitis, and arthritic conditions comprising the application of 3,3-Bis(p-hydroxyphenyl)-phthalide (phenolphthalein) by itself, or in combination with a carrier, or in a mixture with a bicarbonate salt of Group I of the Periodic Table, or in combination with both a carrier and bicarbonate salt. These mixtures can be anhydrous or aqueous solutions and can be applied either by injection, ingestion, or topically.
    Type: Grant
    Filed: January 27, 1981
    Date of Patent: May 13, 1986
    Inventor: John E. McHugh
  • Patent number: 4535090
    Abstract: 3,5-diphenyl-1H-1,2,4-triazoles with contragestational activity of the following formula ##STR1## wherein R may be located on one or the other of the two adjacent nitrogen atoms and may represent hydrogen or a group R.sub.5 CO-- wherein R.sub.5 is an aliphatic saturated or unsaturated hydrocarbyl containing from 1 to 20 carbon atoms, R.sub.1, R.sub.2 and R.sub.3, each independently are selected from hydrogen, lower alkyl and lower alkoxy or R.sub.2 and R.sub.3 together may represent a methylenedioxy group, and R.sub.4 is an aliphatic saturated or unsaturated hydrocarbyl group of from 1 to 20 carbons, with the proviso that when R is hydrogen or an R.sub.5 CO-- group wherein R.sub.5 contains 4 or less carbon atoms, R.sub.4 must contain 5 or more carbons.These compounds have proven to be highly effective in terminating pregnancy in several animal species after a single parenteral injection.
    Type: Grant
    Filed: October 15, 1982
    Date of Patent: August 13, 1985
    Assignee: Gruppo Lepetit S.p.A.
    Inventors: Giulio Galliani, Amedeo Omodei-Sale, Pietro Consonni, Alessandro Assandri
  • Patent number: 4520208
    Abstract: An aromatic polyester comprising two structural units represented by the following formulas A and B in a molar ratio of the structural unit A to the structural unit B being from 70:30 to 90:10 or four structural units represented by the following formulas A, B, C and D in a molar ratio of the total of the structural units A and C to the total of the structural units B and D being from 10:90 to 95:5 and the total of the structural units C and D being less than 50 molar %, and having a reduced viscosity .eta.sp/C of from 0.6 to 4 dl/g as measured at 30.degree. C. at a concentration of 1.
    Type: Grant
    Filed: June 17, 1983
    Date of Patent: May 28, 1985
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Masahiro Hayashi, Seiichi Nozawa, Takashi Oikawa
  • Patent number: 4439610
    Abstract: A process is described for preparing triarylmethane derivatives of a high purity in an extremely high yield from 3-phenylphthalide derivatives and aniline derivatives or indole derivatives with Friedel-Crafts type catalyst or Friedel-Crafts type catalyst and an oxidizing agent.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: March 27, 1984
    Assignee: Kanzaki Paper Manufacturing Company, Ltd.
    Inventors: Mitsuru Kondo, Kiyoshi Yasui, Makoto Miyake, Hiroshi Iwasaki, Tetsuo Shiraishi
  • Patent number: 4399291
    Abstract: Process comprises the combination of the two steps of condensing Y-benzaldehyde with N--R.sup.2 --N--R.sup.3 -aniline and 3--N--R--N--R.sup.1 -benzoic acid, under acidic conditions to produce 2-[(Y-phenyl) (4--N--R.sup.2 --N--R.sup.3 -aminophenyl)methyl]-5--N--R--N--R.sup.1 -aminobenzoic acid, and oxidizing said benzoic acid to produce 3-(Y-phenyl)-3-(4--N--R.sup.2 --N--R.sup.3 -aminophenyl)-6--N--R--N--R.sup.1 -aminophthalide.
    Type: Grant
    Filed: December 9, 1981
    Date of Patent: August 16, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Paul J. Schmidt, Patrick J. Jefferies