Plural Hetero Rings Patents (Class 549/448)
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Patent number: 10919838Abstract: The present invention relates to the production of tri-functional aromatic molecules from diformylfuran, in particular to the production of tri-methyl benzene derivatives such as for example trimellitic acid or 1,2,4-tri(aminomethyl)benzene from diformylfuran and its derivatives.Type: GrantFiled: June 14, 2018Date of Patent: February 16, 2021Assignee: RHODIA OPERATIONSInventors: Eric Muller, Bala N. S Thota
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Patent number: 10822329Abstract: The present invention relates to providing a novel glyceric acid ester which can be produced in a high yield and is expected to be applied as a synthetic intermediate, and a method of producing the same. In addition, the present invention relates to providing a novel glyceric acid ester which exhibits a high recovery in a water-washing step after the reaction and a small work load at the time of production, and is expected to be applied as a synthetic intermediate, and a method of producing the same.Type: GrantFiled: December 26, 2017Date of Patent: November 3, 2020Assignee: KAO CORPORATIONInventor: Takashi Aoki
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Patent number: 9206146Abstract: The present invention relates to a process for the preparation of a hydrogen chloride (HCl) salt of a compound of formula (I) wherein Y1 and Y2 are independently F or Cl, preferably F, said compound of formula (I) containing the cis-isomer and the trans-isomer, wherein the process comprises (1) providing the compound of formula (I) comprised in a first suitable solvent; and (2) treating the compound of formula (I) comprised in the first suitable solvent with HCl comprised in a second suitable solvent to obtain the HCl salt of the compound of formula (I).Type: GrantFiled: May 18, 2011Date of Patent: December 8, 2015Assignee: SANDOZ AGInventors: Martin Langner, Dominic De Souza, Abhinay C. Pise, Sachin Bhuta
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Publication number: 20150118618Abstract: A photoacid generator compound has the formula (1) wherein a, b, c, d, e, x, L1, L2, L3, L4, R1, R2, X, and Z? are defined herein. The photoacid generator compound exhibits good solubility in solvents typically used to formulate photoresist compositions and negative tone developers. Described herein are a photoresist composition including the photoacid generator compound, a coated substrate including the photoresist composition, and a device-forming method utilizing the photoresist composition.Type: ApplicationFiled: October 25, 2013Publication date: April 30, 2015Inventors: Emad Aqad, Irvinder Kaur, Cong Liu, Mingqi Li, Cheng-Bai Xu
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Patent number: 9018403Abstract: Disclosed is a method for producing a tetrahydropyran compound represented by general formula (5) shown in the scheme. Accordingly, a tetrahydropyran derivative is obtained in high yield and with high selectivity without using a highly toxic reagent, and an industrially useful method for producing a tetrahydropyran derivative and an intermediate thereof can be provided. In formulae (1) to (5), R1 and R2 each independently represent a hydrogen atom, a linear, branched, or cyclic alkyl group, or an aromatic group which may have a substituent, and R1 and R2 may be combined to form an alkylene group, thereby forming a ring; and R3 and R4 each independently represent a hydrogen atom or a linear, branched, or cyclic alkyl group, and R3 and R4 may be combined to form an alkylene group, thereby forming a ring.Type: GrantFiled: May 20, 2014Date of Patent: April 28, 2015Assignee: Nissan Chemical Industries, Ltd.Inventors: Hirotaka Kawanami, Kana Yamaguchi, Shota Murase
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Publication number: 20150010469Abstract: Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer, stereoisomer or deuterated analogue thereof, wherein X, R, R1, R2, R3, R4, M1, M2, L1, L2, J1, J2, a1, a2, b1 and b2 are as defined herein, are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.Type: ApplicationFiled: July 3, 2014Publication date: January 8, 2015Applicants: British Columbia Cancer Agency Branch, University of British ColumbiaInventors: Raymond John Andersen, Javier Garcia Fernandez, Marianne Dorothy Sadar
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Publication number: 20140350269Abstract: It refers to a new group of acetal monoesters and diesters which have in its structure the ester function and cyclic ethers that give these products excellent properties as solvency, plasticity in polymers, solubility in polar and nonpolar means, spreadability, wetting, low volatility, non-toxicity and biodegradability. These properties make these products excellent candidates as solvents in formulations of pesticides, agricultural herbicides, for the paint and leather industry in domestic or industrial hygiene formulations; as plasticizers for polymers such as polyvinyl chloride, nitrocellulose, cellulose, acrylics, polyvinyl vinyl and its copolymers; as lubricants in industrial formulations, textile industry; as emollients agents which donate oiliness for the cosmetic industry; as wetting agents that are commonly used, and as biodiesel additives to reduce the freezing point and to improve its combustion.Type: ApplicationFiled: April 28, 2014Publication date: November 27, 2014Applicant: GLYCEROSOLUTION QUÍMICA LTDA.Inventor: Marcelo EIJI BORGES SATO
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Patent number: 8859615Abstract: The present invention provides compounds of Formula (I), compositions comprising an effective amount of a compound of Formula (I), optionally with chemotherapeutic drugs such as a tubulin-binding drug, and methods of their use for reducing the toxicity of cytotoxic agents, treating or preventing cancer or a neuropathic disorder, inducing a chemoprotective phase II enzyme, DNA, or protein synthesis, enhancing the immune system, treating inflammation, improving and enhancing general health or well-being, and methods for making compounds of Formula (I).Type: GrantFiled: August 27, 2009Date of Patent: October 14, 2014Inventors: Samuel J. Danishefsky, Ting-Chao Chou, Xiaoguang Lei, Heedong Yun, Fay Ng, John Hartung, Dalibor Sames
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Publication number: 20140303241Abstract: The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (HNSCC) and hepatoma.Type: ApplicationFiled: March 28, 2014Publication date: October 9, 2014Applicant: AnnCare Bio-Tech Center Inc.Inventors: Sheng-Chu Kuo, Jai-Sing Yang, Min-Tsang Hsieh, Tian-Shung Wu, Kuo-Hsiung Lee, Huei-Wen Chen, Li-Jiau Huang, Hsin-Yi Hung, Tzong-Der Way, Ling-Chu Chang, Hui-Yi Lin, Yung-Yi Cheng, Chin-Yu Liu
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Publication number: 20140296254Abstract: Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds are described that correspond to general formula (I). Also described, are pharmaceutical compositions that include these compounds and methods of using these compounds and compositions for the treatment of chemokine-mediated diseases.Type: ApplicationFiled: October 26, 2012Publication date: October 2, 2014Applicant: GALDERMA RESEARCH & DEVELOPMENTInventors: Branislav Musicki, Jerôme Aubert, Jean-Guy Boiteaux, Laurence Clary, Patricia Rossio, Marlène Schuppli-Nollet
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Publication number: 20140249213Abstract: The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof.Type: ApplicationFiled: March 17, 2014Publication date: September 4, 2014Applicant: ARBOR THERAPEUTICS, LLCInventors: James D. McChesney, John T. Henri, Sylesh Kumar Venkataraman, Mahesh Kumar Gundluru
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Publication number: 20140163127Abstract: The present disclosure relates to the preparation of acrylate, alkacrylate, allyl, and polycarbonate derivatives of hydroxy ketal esters, and uses thereof.Type: ApplicationFiled: November 1, 2013Publication date: June 12, 2014Applicant: SEGETIS, INC.Inventors: Sergey SELIFONOV, Brian Daniel MULLEN, Douglas Alan WICKS, Vivek BADARINARAYANA
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Publication number: 20140135455Abstract: The present disclosure relates to the preparation of ketal compounds from polyols and oxocarboxylates, and uses thereof.Type: ApplicationFiled: January 20, 2014Publication date: May 15, 2014Applicant: SEGETIS, INC.Inventors: Sergey Selifonov, Adam Edward Goetz, Feng Jing
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Patent number: 8653223Abstract: Ketal compounds of the structure I and a method of preparation of the compound from polyols and oxocarboxylates, as well as uses thereof.Type: GrantFiled: April 16, 2009Date of Patent: February 18, 2014Assignee: Segetis, Inc.Inventors: Sergey Selifonov, Adam Edward Goetz, Feng Jing
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Patent number: 8632612Abstract: Disclosed herein are compositions for dyeing keratin fibers, methods of manufacture thereof and articles comprising the same.Type: GrantFiled: September 7, 2011Date of Patent: January 21, 2014Assignee: Segetis, Inc.Inventor: Dorie J. Yontz
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Publication number: 20130344438Abstract: A photoacid generator has the formula (I): wherein R1, R2, R3, L1, L2, L3 X, Z+, a, b, c, d, p, q, and r, are defined herein. A photoresist comprises the photoacid generator, and a coated article comprises the photoresist. The photoresist can be used to form an electronic device.Type: ApplicationFiled: June 25, 2013Publication date: December 26, 2013Applicant: ROHM AND HAAS ELECTRONIC MATERIALS LLCInventors: Emad AQAD, Irvinder KAUR, Cong LIU, Cheng-bai XU, Mingqi LI, Gregory P. PROKOPOWICZ
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Publication number: 20130310288Abstract: Various esterified alkyl ketal ester or hydroxyalkyl ketal ester products are useful as components of organic polymer compositions. The ketal esters are produced in certain transesterifications between alkyl ketal esters and/or hydroxyalkyl ketal esters and polyols, aminoalcohols, polyamines, and/or polycarboxylic acids. The products are excellent plasticizers for a variety of organic polymers, notable poly(vinyl chloride) plastisols. The products are also very good lubricants for many lubrication applications.Type: ApplicationFiled: July 24, 2013Publication date: November 21, 2013Applicant: SEGETIS, Inc.Inventors: Brian D. Mullen, Chunyong Wu, Tara J. Mullen, Marc D. Scholten, Vivek Badarinarayana
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Publication number: 20130303601Abstract: The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof.Type: ApplicationFiled: April 3, 2013Publication date: November 14, 2013Inventors: James D. McChesney, John T. Henri, Sylesh Kumar Venkataraman, Mahesh Kumar Gundluru
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Publication number: 20130303648Abstract: The present disclosure relates to the preparation of ketal compounds from glycerol and levulinic acid and esters, and uses thereof, in particular the manufacture of polyurethanes.Type: ApplicationFiled: July 15, 2013Publication date: November 14, 2013Inventor: Sergey Selifonov
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Patent number: 8436042Abstract: The present disclosure relates to methods of preparation of compounds resulting from the reaction of levulinic esters and epoxidized unsaturated fatty acid esters. The compounds are useful as renewable biomass-based plasticizers for a variety of polymers. Mono-, di- and tri-ketal adducts formed in a reaction between alkyl esters of levulinate and epoxidized unsaturated fatty acid esters derived from vegetable oils are also disclosed.Type: GrantFiled: November 22, 2006Date of Patent: May 7, 2013Assignee: Segetis, Inc.Inventor: Sergey Selifonov
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Publication number: 20130087073Abstract: The invention describes methods of preparation and compositions of plasticizers. The plasticizers include at least 2 alkyl ketal ester moieties and have a molecular weight of greater than 300. In one aspect, the alkyl ketal ester moieties are levulinic ester ketals. Certain compositions contain at least one of an antioxidant, a UV stabilizer, a thermal stabilizer or mixtures thereof, present in the composition from about 0.01 to about 5.0 percent by weight of the total composition.Type: ApplicationFiled: October 9, 2012Publication date: April 11, 2013Applicant: Segetis, Inc.Inventor: Segetis, Inc.
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Publication number: 20130046072Abstract: Monomers having formula (I) and process for their synthesis which comprises the etherification reaction of a halogen-derivative (Z?Cl, Br, I) having formula (III) with the hydroxyl group of the glycerol derivative (IV), according to the following scheme:(Formula III, IV & I) (III) (IV) (I)Type: ApplicationFiled: April 29, 2011Publication date: February 21, 2013Applicant: ENI S.p.A.Inventors: Giuliana Schimperna, Riccardo Po', Andrea Pellegrino, Maria Caldararo
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Publication number: 20130046102Abstract: Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as detergents and emulsifiers in formulations for cleaning, laundry, personal care, cosmetics, and industrial uses.Type: ApplicationFiled: October 22, 2012Publication date: February 21, 2013Applicant: SEGETIS, INC.Inventor: SEGETIS, INC.
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Publication number: 20130022647Abstract: Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules.Type: ApplicationFiled: September 27, 2011Publication date: January 24, 2013Applicant: University of British ColumbiaInventors: Jayachandran N. Kizhakkedathu, Rajesh A. Shenoi, Cedric J. Carter, Donald E. Brooks
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Publication number: 20130011783Abstract: Provided are (meth)acrylate monomers containing acetal moieties, polymers containing a unit formed from such a monomer and photoresist compositions containing such a polymer. The monomers, polymers and photoresist compositions are useful in forming photolithographic patterns. Also provided are substrates coated with the photoresist compositions, methods of forming photolithographic patterns and electronic devices. The compositions, methods and coated substrates find particular applicability in the manufacture of semiconductor devices.Type: ApplicationFiled: December 31, 2011Publication date: January 10, 2013Applicants: Dow Global Technologies LLC, Rohm and Haas Electronic Materials LLCInventors: Matthias S. Ober, Young Cheol Bae, Yi Liu, Seung-Hyun Lee, Jong Keun Park
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Publication number: 20120309819Abstract: The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of chemotherapy associated with the administration of a cancer chemotherapeutic agent to a patient in need thereof.Type: ApplicationFiled: June 5, 2012Publication date: December 6, 2012Inventors: James D. McChesney, John T. Henri, Sylesh Kumar Venkataraman, Mahesh Kumar Gundluru
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Publication number: 20120130092Abstract: It is possible to produce oseltamivir safely and stably in large quantities by using as a starting material tartaric acid, mannitol or arabinose, via dihydroxyhexenoic acid ester of the formula (4c).Type: ApplicationFiled: December 6, 2011Publication date: May 24, 2012Inventors: Teruhiko Ishikawa, Seiki Saito, Takayuki Kudoh, Kotaro Suto, Hironori Nishiuchi, Makoto Okada, Masatoshi Taniguchi
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Publication number: 20120122745Abstract: Various esterified alkyl ketal ester or hydroxyalkyl ketal ester products are useful as components of organic polymer compositions. The ketal esters are produced in certain transesterifications between alkyl ketal esters and/or hydroxyalkyl ketal esters and polyols, aminoalcohols, polyamines and/or polycarboxylic acids. The products are excellent plasticizers for a variety of organic polymers, notable poly(vinyl chloride) plastisols. The products are also very good lubricants for many lubrication applications.Type: ApplicationFiled: December 21, 2011Publication date: May 17, 2012Applicant: SEGETIS, INC.Inventors: Brian D. MULLEN, Chunyong WU, Tara J. MULLEN, Marc D. SCHOLTEN, Vivek BADARINARAYANA
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Publication number: 20120118201Abstract: Disclosed herein is a polyketal adduct obtained by forming an ester between a hydrocarbon polyol and a ketocarboxylic acid to produce an intermediate polyketocarboxylic ester. The intermediate polyketocarboxylic ester can be purified via crystallization to achieve purities of greater than 99.0% and then ketalized to produce the polyketal adduct, which can be used in polymer compositions. The polyketal adduct I is obtained at high purity and at high yield.Type: ApplicationFiled: November 11, 2011Publication date: May 17, 2012Applicant: SEGETIS, INC.Inventors: Brian D. Mullen, Marc D. Scholten, Tara J. Mullen, Cora M. Leibig, Vivek Badarinarayana
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Publication number: 20120121911Abstract: Disclosed herein is a polyhydroxy ketal adduct obtained by the esterification of a hydrocarbon polyol by at least 1.5 equivalents of a ketocarboxy to produce an intermediate ketocarboxylic ester. The intermediate polyketocarboxylic ester is then ketalized to produce the polyhydroxyketal adduct, which can be used to provide a polymeric composition.Type: ApplicationFiled: November 11, 2011Publication date: May 17, 2012Applicant: SEGETIS, INC.Inventors: Brian D. Mullen, Marc D. Scholten, Dorie J. Yontz, Cora M. Leibig, Matthew J. Tjosaas
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Publication number: 20120077989Abstract: The present invention relates to a use of a cyclic imidate as a ligand for catalysis in which the ligand contains sub-structure (Y) as a minimal structural motive, wherein the carbon atoms and the nitrogen atom can be optionally substituted by a chemical substituent.Type: ApplicationFiled: April 6, 2010Publication date: March 29, 2012Inventors: Timothy Noël, Koen Vandyck, Johan Van Der Eycken
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Publication number: 20120041215Abstract: The present invention provides a compound having the structure (I) and processes for the production thereof and the intermediates used in such process.Type: ApplicationFiled: October 25, 2011Publication date: February 16, 2012Inventor: Bruno LINCLAU
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Publication number: 20110294830Abstract: The present invention provides a nitrogen-containing compound represented by formula (I1) (in formula (I1), R0 represents a nitro group or the like, Z represents an optionally substituted aryl group or the like, R3 represents a hydrogen atom or the like, Y represents a nitro group or the like, n represents an integer of 0 to 3, D represents an optionally substituted 5-membered to 8-membered hydrocarbon ring group or heterocyclic group having or not having a substituent other than substituent X, X represents a group represented by formula (II-1) (in formula (II-1), R1 and R2 respectively and independently represent a hydrogen atom or the like), A represents a carbon atom or the like, n1 represents an integer of 0 to 2) or a salt thereof, and an insecticide, miticide, sanitary insect pest control agent, or harmful organism control agent including as an active ingredient thereof the nitrogen-containing compound or the salt thereof.Type: ApplicationFiled: February 5, 2010Publication date: December 1, 2011Applicant: Nippon Soda Co., Ltd.Inventors: Jyun Iwata, Masahiro Kawaguchi, Akiko Mizui
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Patent number: 8053468Abstract: The present disclosure relates to the preparation of ketal compounds from glycerol and levulinic acid and esters, and uses thereof.Type: GrantFiled: November 22, 2006Date of Patent: November 8, 2011Assignee: Segetis, Inc.Inventor: Sergey Selifonov
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Patent number: 8026378Abstract: Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as detergents and emulsifiers in formulations for cleaning, laundry, personal care, cosmetics, and industrial uses.Type: GrantFiled: November 22, 2006Date of Patent: September 27, 2011Assignee: Segetis, Inc.Inventor: Sergey Selifonov
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Publication number: 20110223365Abstract: The present disclosure relates to the preparation of acrylate, alkacrylate, allyl, and polycarbonate derivatives of hydroxy ketal esters, and uses thereof.Type: ApplicationFiled: September 25, 2009Publication date: September 15, 2011Applicant: SEGETIS, INC.Inventors: Sergey Selionov, Brian Daniel Mullen, Douglas Alan Wicks, Vivek Badarinarayana
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Patent number: 8013175Abstract: There is disclosed an episesamin refining method in which a mixture of sesamin components that contains sesamin, episesamin and the like is brought into contact with an aqueous medium to form a slurried mixture, and thereafter the solids are separated from the mixture or the slurried mixture is dissolved in a suitable aqueous medium under heating and, thereafter, the solution is slowly cooled to recrystallize, thereby yielding an episesamin-enriched composition with an increased relative episesamin content. By the present invention, episesamin can be conveniently and efficiently refined from a mixture of sesamin components that mainly comprises sesamin and episesamin.Type: GrantFiled: November 1, 2006Date of Patent: September 6, 2011Assignee: Suntory Holdings LimitedInventors: Yukihiro Aoshima, Masaaki Nakai
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Patent number: 7956087Abstract: The present invention is to provide skin cosmetics and anti-wrinkle agents which are excellent in reducing effect on wrinkle caused by photoaging. Skin cosmetics and anti-wrinkle agents which comprise a sugar alcohol derivative represented by the following formula (1): (wherein n is 1 to 5, preferably n=2.).Type: GrantFiled: April 12, 2006Date of Patent: June 7, 2011Assignee: Kao CorporationInventors: Kyoko Miura, Akinori Haratake
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Publication number: 20110082264Abstract: The present disclosure relates to the preparation of ketal compounds from polyols and oxocarboxylates, and uses thereof.Type: ApplicationFiled: April 16, 2009Publication date: April 7, 2011Applicant: SEGETIS, INC.Inventors: Sergey Selifonov, Adam Edward Goetz, Feng Jing
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Publication number: 20110054191Abstract: A stereoselective synthesis of novel ?-lactam dimers as useful precursors for the preparation of paclitaxel, docetaxel, and analogues thereof. More particularly, the new ?-lactams are prepared from readily available and enantiomerically pure chiral auxiliaries. The ?-lactams are then reacted with a suitably protected taxane to produce diastereomerically enriched side chain-bearing taxanes. Finally, the chiral auxiliary is cleaved and protecting groups are removed to provide the desired taxane.Type: ApplicationFiled: November 4, 2010Publication date: March 3, 2011Applicant: ACCORD HEALTHCARE LTD.Inventors: Mettilda LOURDUSAMY, Gaétan Caron
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Publication number: 20110044918Abstract: The present invention relates to the cosmetic use of a compound of formula (I) and also the cosmetically acceptable salts thereof, solvates thereof and isomers thereof, for non-therapeutic skincare.Type: ApplicationFiled: October 29, 2010Publication date: February 24, 2011Applicant: L'OREALInventors: Xavier Marat, Benoit Muller
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Publication number: 20110028713Abstract: A core of a cyclic structure represented by (—N—(CH2)n—)k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.Type: ApplicationFiled: November 28, 2008Publication date: February 3, 2011Applicants: KYOTO UNIVERSITY, CANON KABUSHIKI KAISHAInventors: Teruyuki Kondo, Hiroshi Tsujita, Zainul Abedin Siddique, Shingo Matsuki, Hiroki Miura, Hidehito Tochio, Tetsuya Matsuda, Michiko Narazaki, Hidetoshi Tsuzuki, Katsuaki Kuge, Yoshinori Tomida, Kimihiro Yoshimura, Tetsuya Yano
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Publication number: 20110021658Abstract: The invention relates to polyketal compounds. The compounds are synthesized by the selective ketalization of oxocarboxylic acids, e.g. keto acids and semialdehydes, and esters thereof with tetrols and higher polyols that products two or more cyclic ketal ester moieties per molecule, wherein the cyclic ketal moieties are situated in a bis-, tris-, or polyketal conformation. The invention further relates to applications of these compounds and subsequent reactions thereof.Type: ApplicationFiled: October 9, 2008Publication date: January 27, 2011Applicant: SEGETIS, INC.Inventors: Sergey Selifonov, Scott David Rothstein, Douglas Alan Wicks, Brian Daniel Mullen, Tara Jane Mullen, Jason Douglass Pratt, Charles Todd Williams, Chunyong (Kevin) Wu, Ning Zhou
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Publication number: 20100324001Abstract: Methods of inhibiting the cytokine or biological activity of Macrophage Migration Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases or conditions where MIF cytokine or biological activity is implicated comprising administration of compounds of formula (I), either alone or as a part of combination therapy. Novel compounds of formula (I) are also provided for.Type: ApplicationFiled: June 30, 2010Publication date: December 23, 2010Applicant: Cortical Pty LTDInventors: Eric Francis Morand, Magdy Naguib Iskander, Colin Edward Skene
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Publication number: 20100292373Abstract: The present disclosure relates to methods of preparation of compounds resulting from the reaction of levulinic esters and epoxidized unsaturated fatty acid esters. The compounds are useful as renewable biomass-based plasticizers for a variety of polymers. Mono-, di- and tri-ketal adducts formed in a reaction between alkyl esters of levulinate and epoxidized unsaturated fatty acid esters derived from vegetable oils are also disclosed.Type: ApplicationFiled: November 22, 2006Publication date: November 18, 2010Inventor: Sergey Selifonov
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Publication number: 20100292491Abstract: The reaction of alcohols with oxocarboxylates to form acetals or ketals is catalyzed by unexpectedly low levels of protic acids. By employing low acid catalyst levels compared to amounts conventionally used, rapid formation of acetal or ketal is facilitated while the formation of oxocarboxylate esters is minimized. Further employing a significant molar excess of oxocarboxylate in conjunction with low acid catalyst level gives rise to the rapid and clean formation of acetals and ketals from oxocarboxylates and alcohols.Type: ApplicationFiled: April 9, 2010Publication date: November 18, 2010Applicant: SEGETIS, INC.Inventors: Sergey Selifonov, Scott D. Rothstein, Brian D. Mullen
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Publication number: 20100222603Abstract: Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as detergents and emulsifiers in formulations for cleaning, laundry, personal care, cosmetics, and industrial uses.Type: ApplicationFiled: November 22, 2006Publication date: September 2, 2010Inventor: Sergey Selifonov
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Patent number: 7772485Abstract: This disclosure relates to a polymer containing a first comonomer repeat unit and a second comonomer repeat unit different from the first comonomer repeat unit. The first comonomer repeat unit includes a cyclopentadithiophene moiety. The polymer can be used as a photoactive material in a photovoltaic cell. This disclosure also relates to such photovoltaic cells, as well as modules containing such photovoltaic cells.Type: GrantFiled: March 14, 2006Date of Patent: August 10, 2010Assignee: Konarka Technologies, Inc.Inventors: Russell Gaudiana, Richard Kingsborough, David Waller, Zhengguo Zhu
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Patent number: 7683043Abstract: Membrane permeable prodrugs of creatine phosphate analogs, pharmaceutical compositions comprising membrane permeable prodrugs of creatine phosphate analogs, and methods of treating diseases such as ischemia, heart failure, and neurodegenerative disorders comprising administering prodrugs of creatine phosphate analogs, or pharmaceutical compositions thereof are disclosed.Type: GrantFiled: June 6, 2007Date of Patent: March 23, 2010Assignee: XenoPort, Inc.Inventors: Noa Zerangue, Qingzhi Gao, William J. Dower
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Publication number: 20090054668Abstract: The present invention provides a compound having the structure (I) and processes for the production thereof and the intermediates used in such process.Type: ApplicationFiled: February 24, 2006Publication date: February 26, 2009Inventor: Bruno Linclau