Unsaturation In Acid Moiety Patents (Class 560/183)
  • Patent number: 10442752
    Abstract: One object of the invention is to provide a method for preparing a 9,9-dialkoxy-7-nonynoate ester and (7E)-7,9-decadienoate ester, which are valuable as intermediates. The method for preparing a (7E)-7,9-decadienoate ester (5) comprises at least steps of: hydrolyzing a 9,9-dialkoxy-7-nonenoate ester (2), R3O(R2O)CHCH?CH(CH2)5CO2R1, to form a (7E)-9-oxo-7-nonenoate ester (3); and subjecting the (7E)-9-oxo-7-nonenoate ester (3) to a Wittig reaction with a triarylphosphonium methylide (4), Ar3P?CH2, to form the (7E)-7,9-decadienoate ester (5). The 9,9-dialkoxy-7-nonenoate ester may be prepared by, for example, reducing a 9,9-dialkoxy-7-nonynoate ester (1).
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: October 15, 2019
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Yuki Miyake, Takeshi Kinsho, Ryo Komatsu
  • Patent number: 10273393
    Abstract: The present invention relates to a method of producing an alkoxylene derivative and an application thereof. A mixture is firstly subjected to a first reaction for obtaining a first intermediate. The mixture includes an alkyl alcohol compound and a glycidyl ether compound. A second reaction is performed to the first intermediate and an epoxyalkyl compound, thereby obtaining the alkoxylene derivative. The alkoxylene derivative can effectively improve antistatic property and anti-fogging property.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: April 30, 2019
    Assignee: SINO-JAPAN CHEMICAL CO., LTD.
    Inventors: Chung-Che Chuang, Ya-Hui Lin
  • Patent number: 10125080
    Abstract: A method of producing high purity polyol esters comprises reacting a polyol with an excess amount of a linear or branched aliphatic monocarboxylic C3-20 acid to esterify less than the total amount of the polyol present to form an intermediate reaction composition having a hydroxyl value of from 7 to about 50 mg KOH/g. An anhydride of the corresponding linear or branched aliphatic monocarboxylic C3-20 acid is added to the intermediate reaction composition in an amount of from 1 to about 2.5 equivalents of available OH in the intermediate composition to form a reaction mixture. The reaction mixture is heated for 5-30 minutes or until all of the corresponding anhydride has reacted to form a reaction product. The reaction product is then de-acidified. No metal or acid catalyst or bleaching agents are present in any of the above reaction steps at a concentration above about 15 ppm.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: November 13, 2018
    Assignee: CARGILL, INCORPORATED
    Inventor: John Eubanks
  • Patent number: 9580526
    Abstract: Described herein is a composition comprising a fluorinated polysulfinic acid or a salt thereof having the following formula (I): wherein X1, X2, and X3 are independently selected from H, F, Cl, Br, I, CF3, and CH3 and wherein at least one of X1, X2, or X3 is H; R1 is a linking group; Z1 and Z2 are independently selected from Br, Cl, I, F, CF3, and a perfluorinated alkyl group; M is a cation; p is 0 or 1; and n is at least 2. Also described is a method of making the partially fluorinated polysulfinic acid or salt thereof.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: February 28, 2017
    Assignee: 3M Innovative Properties Company
    Inventors: Zai-Ming Qiu, Gregg D. Dahlke, Tatsuo Fukushi, Werner M. Grootaert, Miguel A. Guerra
  • Patent number: 9284253
    Abstract: A process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms, is characterized in that a mixture of the starting compounds is allowed to react in the presence of a Lewis acid containing at least one element of groups 4 to 14 of the periodic table of the elements as a catalyst and in the presence of an adsorbent with removal of the water formed, and then the crude ester obtained is aftertreated by adding a further adsorbent which is an acidic activated carbon having a pH of 1 to 6.5.
    Type: Grant
    Filed: August 10, 2013
    Date of Patent: March 15, 2016
    Assignee: OXEA GMBH
    Inventors: Guido D. Frey, Tonia Weber, Jörg Arnold, Thorsten Kreickmann, Heinz Strutz
  • Patent number: 9234058
    Abstract: Described herein is a composition comprising a fluorinated polysulfinic acid or a salt thereof having the following formula (I): wherein X1, X2, and X3 are independently selected from H, F, Cl, Br, I, CF3, and CH3 and wherein at least one of X1, X2, or X3 is H; R1 is a linking group; Z1 and Z2 are independently selected from Br, Cl, I, F, CF3, and a perfluorinated alkyl group; M is a cation; p is 0 or 1; and n is at least 2. Also described is a method of making the partially fluorinated polysulfinic acid or salt thereof.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: January 12, 2016
    Assignee: 3M Innovative Properties Company
    Inventors: Zai-Ming Qiu, Gregg D. Dahlke, Tatsuo Fukushi, Werner M. Grootaert, Miguel A. Guerra
  • Patent number: 9156771
    Abstract: Enolate salts of 4-fluoro-2-hydroxymethylene-3-oxobutyrates of formula wherein R1 is C1-10 alkyl, R2 and R3 are independently hydrogen or fluorine, M is an alkali or alkaline earth metal, and n is 1 or 2, are prepared from enolate salts of the corresponding 4-fluoro-3-oxobutyrates and carbon monoxide. The enolate salts of formula I can be alkylated or acylated to obtain the corresponding enol ethers and esters. The 4-fluoro-3-oxobutyrate starting material can be prepared from 1,1-difluoroethyl methyl ethers by SbF5-catalyzed fluoromethane elimination followed by halogen exchange with lithium chloride, reacting the thus obtained fluoroacetyl chloride with ketene and quenching with the appropriate alcohol R1—OH.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: October 13, 2015
    Assignee: LONZA LTD
    Inventors: Martina Eichenberger, Paul Hanselmann, Florencio Zaragoza Dörwald
  • Publication number: 20150148560
    Abstract: Provided herein are methods that utilize polyhydroxyalkanoates (PHAs) as a substrate for further conversion to C4 and C5 compounds. Polyhydroxyalkanoates can undergo esterification to yield alkyl hydroxyalkanoates and alkyl alkenoates, which may serve as useful precursors in the production of alkadienes and alkenedioic acids, including for example butadiene and butenedioic acid.
    Type: Application
    Filed: May 31, 2013
    Publication date: May 28, 2015
    Applicant: MICROMIDAS, INC.
    Inventors: Ryan L. Smith, John Bissell, Makoto N. Masuno, Douglas Cannon, Alex B. Wood, Marc Foster
  • Patent number: 8920524
    Abstract: Disclosed are polyisobutenyl alcohols and substituted polyisobuentyl alcohols of the formula: wherein n is an integer from 5 to 90, R is selected from the group consisting of hydrogen, haloalkyl, alkoxycarbonyl and substituted aryl wherein at least one substituent group of the substituted aryl is selected from cyano, nitro and alkoxycarbonyl.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: December 30, 2014
    Assignee: Chevron Oronite Company LLC
    Inventors: Richard E. Cherpeck, Ruth Smocha
  • Publication number: 20140364643
    Abstract: Preparation of derivatives of ?-hydroxycarboxylic acid, including ?-hydroxycarboxylic acid esters, ?,?-unsaturated carboxylic acids, esters of ?,?-unsaturated carboxylic acid, and alkoxy derivatives.
    Type: Application
    Filed: August 25, 2014
    Publication date: December 11, 2014
    Applicant: Cargill, Incorporated
    Inventors: Paraskevas Tsobanakis, Xiangsheng Meng, Timothy Walter Abraham
  • Publication number: 20140296364
    Abstract: The invention relates to a dental material which comprises a polymerizable bisphosphonic acid of Formula I: The invention also relates to the use of a polymerizable bisphosphonic acid of Formula I for the preparation of a dental material and in particular for the preparation of an adhesive, cement or composite.
    Type: Application
    Filed: December 6, 2012
    Publication date: October 2, 2014
    Inventors: Norbert Moszner, Yohann Catel, Jörg Angermann, Thorsten Bock, Volker Rheinberger
  • Publication number: 20140248563
    Abstract: A composition includes a polymer component including a first polymer having a first structural unit represented by a following formula (1), and a solvent. In the formula (1), R1 represents a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. R2 represents a single bond or a divalent organic group having 1 to 20 carbon atoms. R3 represents a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. RQ represents a perfluoroalkyl group having 1 to 5 carbon atoms. RX represents a hydrogen atom or a monovalent base-labile group.
    Type: Application
    Filed: May 9, 2014
    Publication date: September 4, 2014
    Applicant: JSR CORPORATION
    Inventors: Kiyoshi TANAKA, Shinya MINEGISHI, Kazunori KUSABIRAKI, Takahiro HAYAMA
  • Publication number: 20140221439
    Abstract: The present disclosure relates to lipid compounds of the general formula (I): R1—O—C(R2)(R3)—X??(I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be chosen from different substituents; and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide; or a pharmaceutically acceptable salt, solvate, solvate of such salt, or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
    Type: Application
    Filed: April 11, 2014
    Publication date: August 7, 2014
    Applicant: PRONOVA BIOPHARMA NORGE AS
    Inventors: Ragnar Hovland, Anne Kristin HOLMEIDE, Tore SKJÆRET, Morten BRÆNDVANG
  • Patent number: 8791293
    Abstract: According to the present invention, there is provided a fluorine-containing sulfonate resin having a repeating unit of the following general formula (3). In order to prevent deficiency such as roughness after pattern formation or failure in pattern formation, the fluorine-containing sulfonate resin incorporates therein a photoacid generating function and serves as a resist resin in which “a moiety capable of changing its developer solubility by the action of an acid” and “a moiety having a photoacid generating function” are arranged with regularity.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: July 29, 2014
    Assignee: Central Glass Company, Limited
    Inventors: Kazunori Mori, Satoru Narizuka, Fumihiro Amemiya, Masaki Fujiwara
  • Patent number: 8735436
    Abstract: The present disclosure relates to lipid compounds of the general formula (I): R1-O—C(R2)(R3)-X??(I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be chosen from different substituents; and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide; or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: May 27, 2014
    Assignee: Pronova Biopharma Norge AS
    Inventors: Ragnar Hovland, Anne Kristin Holmeide, Tore Skjæret, Morten Brændvang
  • Patent number: 8592622
    Abstract: A polymerizable fluorine-containing compound represented by formula (1), wherein R1 represents a polymerizable double-bond containing group, R2 represents an acid-labile protecting group, R3 represents a fluorine atom or fluorine-containing alkyl group, and W represents a bivalent linking group. This compound can provide a fluorine-containing polymer compound that has a weight-average molecular weight of 1,000-1,000,000 and contains a repeating unit represented by formula (2), wherein R2, R3 and W are defined as above, each of R4, R5 and R6 independently represents a hydrogen atom, fluorine atom or monovalent organic group, at least two of R4, R5 and R6 may be combined to form a ring. This polymer compound can provide a resist composition capable of forming a pattern that is transparent to exposure light and superior in rectangularity.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: November 26, 2013
    Assignee: Central Glass Company, Limited
    Inventors: Yoshimi Isono, Jonathan Joachim Jodry, Satoru Narizuka
  • Publication number: 20130289300
    Abstract: The present invention provides a method and system for separating linalyl acetate from Lavender essential oil and preparing its derivatives, whereby the supercritical fluid technology is used to feed Lavender essential oil and supercritical solvent into the first separating tank, where linalyl acetate and linalool are separated from Lavender essential oil; then linalyl acetate is conveyed to the second separating tank, where linalyl acetate is separated with wax-containing oily substance to obtain high-concentration linalyl acetate; next linalool and vitamin C solution are conveyed to a reaction tank for esterification synthesis, and the reaction tank is filled with acid resin catalyst to obtain linalool-vitamin C derivative; with this design, it is possible to reduce the nervous tension, and adjust high-concentration linalyl acetate affecting physiological and psychological stress, as well as vitamin C derivative with anti-oxidizing oily fragrance.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 31, 2013
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20130267658
    Abstract: There is provided oligomers comprising a highly fluorinated sulfinate oligomers.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 10, 2013
    Applicant: 3M Innovative Properties Company
    Inventors: Miguel A. Guerra, Gregg D. Dahlke, Denis Duchesne, Tatsuo Fukushi, Werner M.A. Grootaert, Zai-Ming Qiu
  • Patent number: 8524937
    Abstract: The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms by partial recycling of the aliphatic monocarboxylic acid removed into the esterification reaction or into subsequent esterification batches.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: September 3, 2013
    Assignee: Oxea GmbH
    Inventors: Michael Adamzik, Thomas Müller, Willy Schulz, Heyko Jürgen Schultz
  • Patent number: 8524938
    Abstract: The present invention relates to a process for lightening the color of polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms, wherein the reaction product is worked up without using adsorbents and comprises a treatment with ozone or ozone-containing gases and an immediately subsequent steam treatment with subsequent drying.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: September 3, 2013
    Assignee: Oxea GmbH
    Inventors: Guido D. Frey, Thorsten Kreickmann, Heinz Strutz
  • Publication number: 20130217901
    Abstract: The invention relates to a method of producing optically active 4-chloro-3-hydroxybutanal compound (2) by reacting chloroacetaldehyde with aldehyde compound (1) in the presence of optically active pyrrolidine compound (5). wherein each symbol is as defined in the specification.
    Type: Application
    Filed: October 19, 2011
    Publication date: August 22, 2013
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventor: Yujiro Hayashi
  • Publication number: 20130189222
    Abstract: An unsaturated hydroxyl-ester pheromone for the neotropical root weevil Diaprepes abbreviatus has been isolated, identified and synthesized. It is useful for trapping the weevil to reduce or prevent damage to plants.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 25, 2013
    Applicant: The United States of America, as represented by the Secretary of Agriculture
    Inventor: The United States of America, as represented by the Secretary of Agriculture
  • Patent number: 8410305
    Abstract: Highly efficient methods are provided for preparing key intermediates in the synthesis of epothilones and use new alane reagents which are broadly applicable and can provide selected components having a variety of substituents groups.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: April 2, 2013
    Assignee: Kosan Biosciences Incorporated
    Inventors: Yue Chen, Yong Li
  • Publication number: 20130072712
    Abstract: A method for producing ?-substituted acrylate esters is provided which can be suitably used as an industrial method for producing ?-substituted acrylate esters because the method does not have problems of apparatus corrosion or does not require waste detoxification and allows reaction in a short time with high yield. The method for producing an ?-substituted acrylate ester includes a step of carrying out a reaction of a compound having a specific structure and an active hydrogen-containing compound under a condition where a tertiary amine and an acid and/or a salt thereof coexist.
    Type: Application
    Filed: May 23, 2011
    Publication date: March 21, 2013
    Applicant: NIPPON SHOKUBAI CO, LTD
    Inventors: Takahiro Kawamoto, Atsushi Tachibana
  • Publication number: 20130072703
    Abstract: The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerisation of a hydroxy-substituted C10-30 carboxylic acid into a polyester, an optionally hydroxy-substituted C10-30 carboxylic acid, a C10-30-hydrocarbyl substituted acylating agent, and a polyolefin-substituted maleic anhydride. The invention further provides compositions for inks, thermoplastics, plasticisers, plastisols, crude grinding and flush.
    Type: Application
    Filed: November 16, 2012
    Publication date: March 21, 2013
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventor: Lubrizol Advanced Materials, Inc.
  • Publication number: 20130072704
    Abstract: The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerisation of a hydroxy-substituted C10-30 carboxylic acid into a polyester, an optionally hydroxy-substituted C10-30 carboxylic acid, a C10-30-hydrocarbyl substituted acylating agent, and a polyolefin-substituted maleic anhydride. The invention further provides compositions for inks, thermoplastics, plasticisers, plastisols, crude grinding and flush.
    Type: Application
    Filed: November 16, 2012
    Publication date: March 21, 2013
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventor: Lubrizol Advanced Materials, Inc.
  • Publication number: 20120296093
    Abstract: This application discloses a novel process for the preparation of himbacine analogs useful as thrombin receptor antagonists. The process is based in part on the use of a base-promoted dynamic epimerization of a chiral nitro center.
    Type: Application
    Filed: July 31, 2012
    Publication date: November 22, 2012
    Inventors: George Wu, Anantha R. SUDHAKAR, Tao WANG, Ji XIE, Frank Xing CHEN, Marc POIRIER, Mingsheng HUANG, Vijay SABESAN, Daw-long KWOK, Jian CUI, Xiaojing YANG, Tiruvettipuram K. THIRUVENGADAM, Jing LIAO, Ilia A. Zavialov, Hoa N. NGUYEN, Ngiap Kie LIM
  • Patent number: 8304572
    Abstract: This invention relates to processes for preparing fluoroalcohol-substituted (meth)acrylate esters. This invention also relates to block copolymers incorporating repeat units derived from fluoroalcohol-substituted (meth)acrylate esters, and photoresists derived therefrom.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: November 6, 2012
    Assignee: E I du Pont de Nemours and Company
    Inventor: William Brown Farnham
  • Publication number: 20120277311
    Abstract: Compounds having the active site of natural lipoxins, but a longer tissue half-life are disclosed. In particular, 15-epi-lipoxins and their use in ameliorating undesired cell proliferation, which characterizes diseases such as cancer, are also disclosed.
    Type: Application
    Filed: October 21, 2010
    Publication date: November 1, 2012
    Inventor: Charles N. Serhan
  • Patent number: 8282872
    Abstract: It's object is to provide a (meth)acrylate compound excellent in photocurability, a curable composition comprising the compound and excellent in all of pattern accuracy, peelability, surface hardness, elasticity recovery and solvent resistance, an optical nanoimprint composition and a cured product of the curable composition and a method for producing it, especially to provide a composition favorable for a permanent film for flat panel displays, etc. A (meth)acrylate compound represented by the following formula (1): wherein R1 represents a hydrogen atom or a methyl group, R2 represents a substituent having carbon atoms of 2 to 6 and having a carbon-carbon double bond, X represents an organic group having carbon atoms of 1 to 10, m and n each are an integer of 1 to 3.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: October 9, 2012
    Assignee: FUJIFILM Corporation
    Inventors: Akinori Fujita, Takashi Takayanagi, Hiroyuki Yonezawa
  • Patent number: 8278479
    Abstract: An optically active, fluorine-containing carbonyl-ene product is produced by reacting a fluorine-containing ?-ketoester with an alkene in the presence of a transition metal complex having an optically active ligand. There are Mode 1 of conducting this reaction in the absence of reaction solvent, Mode 2 of conducting this reaction in a solvent that is low in relative dielectric constant, and Mode 3 of conducting this reaction in a halogenated hydrocarbon-series solvent. In each of these three modes, it is possible to produce the optically active, fluorine-containing carbonyl-ene product with low cost.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: October 2, 2012
    Assignees: Central Glass Company, Limited, Tokyo Institute of Technology
    Inventors: Koichi Mikami, Kohsuke Aikawa, Akihiro Ishii, Kaori Mogi, Takashi Ootsuka
  • Patent number: 8273792
    Abstract: (Neuro)protectin D1 (1OR,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid) and 15,16-dehydro-PD1 and their derivatives are useful in the treatment of airway inflammation, especially asthma.
    Type: Grant
    Filed: October 3, 2006
    Date of Patent: September 25, 2012
    Assignees: The Brigham and Women's Hospital, Inc., The University of Southern California
    Inventors: Charles N. Serhan, Nicos A. Petasis, Bruce D. Levy
  • Publication number: 20120215024
    Abstract: Retinyl hydroxyesters and retinyl oligo-hydroxyesters were prepared using a chemoenzymatic process from retinol and short chain esters of hydroxycarboxylic acids or short chain esters of hydroxycarboxylic acids. The presence of the hydroxyl group on the acid can result in a mixture of esters from various oligomers of the hydroxycarboxylic acid. The retinyl ester products are readily enzymatically hydrolyzed in vitro, which indicates that application to the skin should result in release of the anti-aging ingredient retinol (without the inherent instability and irritation) along with the acid, which, if chosen appropriately, should also have desirable biological effects. This combination should be effective as an anti-aging skin care ingredient.
    Type: Application
    Filed: February 21, 2011
    Publication date: August 23, 2012
    Applicant: Eastman Chemical Company
    Inventor: Neil Warren Boaz
  • Publication number: 20120122940
    Abstract: The present disclosure relates to lipid compounds of the general formula (I): R1-O—C(R2)(R3)-X??(I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be chosen from different substituents; and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide; or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
    Type: Application
    Filed: May 7, 2010
    Publication date: May 17, 2012
    Inventors: Ragnar Hovland, Anne Kristin Holmeide, Tore Skjæret, Morten Brændvang
  • Patent number: 8076402
    Abstract: A bisphenol monoester compound represented by the formula (1): (in the formula (1), Rs each represent independently a hydrogen atom or a methyl group, and R? represents an alkyl group of a carbon number of 1 to 6, or a hydrogen atom).
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: December 13, 2011
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Ryoji Soma, Toyomochi Tamato, Masatsugu Akiba, Tatsumi Nuno
  • Patent number: 8044235
    Abstract: A monomer is provided which is excellent in reactivity, can give high heat resistance and high refractive index, and has two or more polymerizable functional groups with different polymerization properties and an aromatic ring in the molecule. An industrial advantageous process for producing the monomer is also provided. The monomer is an aromatic isocyanate compound containing a (meth)acryloyl group, and is represented by Formula (I): wherein R1 is a single bond or a linear or branched alkylene group of 1 to 5 carbon atoms, R2 is a hydrogen atom or a methyl group, R3 is a single bond or a linear or branched alkylene group of 1 to 3 carbon atoms, X is independently a halogen atom or an electron-withdrawing group, m is an integer ranging from 0 to 4, n is an integer ranging from 1 to 3, and 1?m+n?5.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: October 25, 2011
    Assignee: Showa Denko K.K.
    Inventors: Kaneo Nozawa, Katsutoshi Ohno, Yotaro Hattori
  • Publication number: 20110245477
    Abstract: The present invention generally relates to methods for performing metathesis reactions, including cross-metathesis reactions. Methods described herein exhibit enhanced activity and stereoselectivity, relative to known methods, and are useful in the synthesis of a large assortment of biologically and therapeutically significant agents.
    Type: Application
    Filed: February 8, 2011
    Publication date: October 6, 2011
    Applicants: Trustees of Boston College, Massachusetts Institute of Technology
    Inventors: Amir H. Hoveyda, Simon J. Meek, Robert V. O'Brien, Josep Llaveria Cros, Richard R. Schrock
  • Publication number: 20110245384
    Abstract: The invention provides a process for the production of a functionalised carbon (nano)material comprising heating a carbon (nano)material in an inert atmosphere to produce a surface-activated carbon (nano)material and incubating said surface-activated carbon (nano)material with a chemical species capable of reacting with the surface-activated carbon (nano)material.
    Type: Application
    Filed: July 2, 2009
    Publication date: October 6, 2011
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Alexander Bismarck, Milo Sebastian Peter Shaffer, Robert Menzel, Michael Q. Tran, Angelika Menner
  • Publication number: 20110245528
    Abstract: The invention relates to novel resolvin compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel resolvin compounds of the invention.
    Type: Application
    Filed: September 23, 2009
    Publication date: October 6, 2011
    Inventor: C. Eric Schwartz
  • Patent number: 7977378
    Abstract: Compositions and methods are provided for the treatment of obesity in a human in need of such treatment which comprises administration to the human of a therapeutically effective amount of a compound of a weight loss enhancing beta-3-adrenergic compound of Cycle I, and a different weight loss enhancing adenylate cyclase receptor replenishing compound of Cycle II, in conjunction with a pharmaceutically acceptable diluent or carrier, wherein the Compound of Cycle I and the compound of Cycle II are administered sequentially. The composition may be present as a kit having each sequence in blister packs.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: July 12, 2011
    Inventor: Adel Villalobos
  • Patent number: 7964696
    Abstract: The present invention relates to chain extenders, processes for their preparation and their use in the preparation of biocompatible biodegradable polyurethanes and polyurethane ureas for biomedical applications such as stents, scaffolds for tissue engineering.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: June 21, 2011
    Assignee: Polynovo Biomaterials Pty Limited
    Inventors: Pathiraja Arachchillage Gunatillake, Timothy Graeme Moore, Raju Adhikari
  • Publication number: 20110130509
    Abstract: The present invention relates to a (meth)acrylate monomer of the general formula (I) in which R1 is hydrogen or a methyl group, X is oxygen or a group of the formula NR? in which R? is hydrogen or a radical having 1 to 6 carbon atoms, R2 is an alkylene group having 1 to 22 carbon atoms, Y is oxygen, sulphur or a group of the formula NR?, in which R? represents hydrogen or a radical having 1 to 6 carbon atoms, and R3 is an unsaturated radical having 8 carbon atoms and at least two double bonds. The present invention further relates to a process for preparing the monomers set out above, to polymers obtainable from this monomer mixture, and to coating materials which comprise the stated polymers.
    Type: Application
    Filed: August 31, 2009
    Publication date: June 2, 2011
    Applicant: Evonik Roehm GmbH
    Inventors: Thorben Schuetz, Joachim Knebel, Mario Gomez Andreu, Ralf Jackstell, Matthias Beller, Anne Grotevendt, Maria Christine Breiner
  • Publication number: 20110087045
    Abstract: The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms by partial recycling of the aliphatic monocarboxylic acid removed into the esterification reaction or into subsequent esterification batches.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 14, 2011
    Inventors: Michael Adamzik, Thomas Müller, Willy Schulz, Heyko Jürgen Schultz
  • Publication number: 20110087044
    Abstract: The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms in the presence of an adsorbent and subsequent steam treatment in the course of workup of the crude ester.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 14, 2011
    Inventors: Tonia Weber, Oliver Borgmeier, Guido Frey, Heinz Strutz
  • Publication number: 20110087046
    Abstract: The present invention relates to a process for lightening the color of polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms, wherein the reaction product is worked up without using adsorbents and comprises a treatment with ozone or ozone-containing gases and an immediately subsequent steam treatment with subsequent drying.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 14, 2011
    Inventors: Guido Frey, Thorsten Kreickmann, Heinz Strutz
  • Patent number: 7906676
    Abstract: The present invention relates to a novel process for the production of 3-amino-5-fluoro-4-dialkoxypentanoic acid ester used in the precursor of 3-amino-5-fluoro-4-oxopentanoic acid, represented by the following formula (I): wherein R1 and R2 are as defined in the Description.
    Type: Grant
    Filed: August 9, 2007
    Date of Patent: March 15, 2011
    Assignee: LG Life Sciences Ltd.
    Inventors: Hyun Ik Shin, Hyeong Wook Choi, Jae Hoon Lee, Kyu Woong Lee
  • Publication number: 20100312007
    Abstract: A solution component recovery method, a solution component recovery apparatus, and an impregnation process/impregnation component recovery system for separating a first component from a second component. The separation between the first and second components is accomplished by reducing the pressure on a solution that contains the first component, which results in the solidification of the first component in the solution at a temperature that is equal to or higher than a predetermined solidification temperature. The second component, in which the first component is dissolved, is evaporated at a temperature range that is less than the predetermined solidification temperature. The evaporated second component is then recovered by a cooling step.
    Type: Application
    Filed: April 28, 2010
    Publication date: December 9, 2010
    Applicants: AISIN AW CO., LTD., SUTAI CO., LTD., KANSAI CHEMICAL ENGINEERING CO., LTD.
    Inventors: Hiroyuki Kawatsu, Naoshi Ito, Yasuhiko Sugino, Mitsuo Yamamoto, Hideo Noda, Goro Nishimura
  • Publication number: 20100274042
    Abstract: A process for preparing (meth)acrylic esters (E) of alcohols (A) comprising polyalkoxy groups, in which alcohols (A) which comprise polyalkoxy groups and are of the formula (I) RO—[(CH2)mO]n—H ??(I) in which m is an integer from 1 to 10, n is an integer from 1 to 100 and R is a straight-chain saturated or unsaturated alcohol having 1 to 30 carbon atoms, are transesterified with at least one (meth) acrylic ester (D) in the presence of at least one inorganic salt (S).
    Type: Application
    Filed: April 21, 2010
    Publication date: October 28, 2010
    Applicant: BASF SE
    Inventors: Virginie BETTE, Jochen Petzoldt, Hermann Bergmann
  • Publication number: 20100273909
    Abstract: Disclosed is a urethane (meth)acrylate oligomer which is obtained by reacting at least one polyoxyalkylene polyol (A), at least one monool (B1) soluble in the component (A) and/or at least one silane coupling agent (B2) reactive with an isocyanate group, at least one polyisocyanate (C) and at least one hydroxylated mono(meth)acrylate compound (D) at a ratio at which the equivalent weights of hydroxy groups, active hydrogen groups and isocyanate groups in the respective components satisfy the following formulae (1)-(3). The urethane (meth)acrylate oligomer does not substantially contain an unreacted isocyanate group. B(active hydrogen)+D(OH)=C(NCO)?A(OH) (1) 1.05?C(NCO)/A(OH)?2 (2) {C(NCO)?2A(OH)+2 m}×0.35?D(OH)?{C(NCO)?2A(OH)+2 m}×0.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 28, 2010
    Inventors: Yoshinobu Ogawa, Kazutoshi Doki, Osamu Kawata, Yoshihiro Tani
  • Patent number: RE42221
    Abstract: A polymerizable liquid crystal composition containing compounds represented by the formula (1-1) and the formula (1-2), compounds represented by the formula (2-1) and the formula (2-2), and a compound represented by the formula (3-1): the polymerizable liquid crystal composition having homogeneous, homeotropic, or hybrid alignment, which can be coated on a support substrate, for example, of a transparent plastic film such as a triacetyl cellulose film or cycloolefin polymer film, or glass, and is aligned on a substrate as a polymer film while maintaining the alignment.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: March 15, 2011
    Assignees: Chisso Corporation, Chisso Petrochemical Corporation
    Inventors: Maiko Ito, Masami Kimura, Ryushi Shundo