Oxy, Not Bonded Directly To A Ring, In Same Side Chain As Ester Function Patents (Class 560/60)
  • Patent number: 10077495
    Abstract: Single walled carbon nanotubes can be synthesized and production efficiency of carbon nanotubes can be enhanced by a method including a supplying step (S11) in which particulate carriers are supplied into a drum, a sputtering step (S12) for supporting a catalyst, in which sputtering is performed while this drum 10 is rotated around the axis and is swung so that one end portion and the other end portion in the axial direction of the drum 10 are relatively vertically switched, and a recovering step (S13) in which the particulate carriers are recovered by inclining the drum to discharge the particulate carriers from the drum.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: September 18, 2018
    Assignee: HITACHI CHEMICAL COMPANY, LTD.
    Inventors: Shunsuke Ueda, Eisuke Haba
  • Patent number: 10041165
    Abstract: Single walled carbon nanotubes can be synthesized and production efficiency of carbon nanotubes can be enhanced by a method including a supplying step (S11) in which particulate carriers are supplied into a drum, a sputtering step (S12) for supporting a catalyst, in which sputtering is performed while this drum 10 is rotated around the axis and is swung so that one end portion and the other end portion in the axial direction of the drum 10 are relatively vertically switched, and a recovering step (S13) in which the particulate carriers are recovered by inclining the drum to discharge the particulate carriers from the drum.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: August 7, 2018
    Assignee: HITACHI CHEMICAL COMPANY, LTD.
    Inventors: Shunsuke Ueda, Eisuke Haba
  • Patent number: 9012678
    Abstract: The invention relates to improved process for the preparation of fesoterodine and its pharmaceutically acceptable salt, specifically fesoterodine fumarate of formula (1). The invention relates to solid state forms of a novel salt of fesoterodine and process for the preparation thereof. The invention also relates to highly pure fesoterodine fumarate substantially free of impurity X at RRT 1.37. The invention also provides solid particles of pure fesoterodine fumarate wherein 90 volume-percent of the particles (D90) have a size of higher than 200 microns.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: April 21, 2015
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Kuldeep Natwarlal Jain
  • Publication number: 20150105532
    Abstract: Provided is a method of depolymerizing polyesters from post-consumer products, such as beverage bottles, to produce a high purity reaction product. For the depolymerization reaction, the polyesters are reacted with an alcohol having 2 to 5 carbons and an amine organocatalyst at a temperature of about 150° C. to about 250° C. In one application, the use an organocatalyst with a boiling point significantly lower than the boiling point of the reactant alcohol allows for the ready recycling of the amine organocatalyst. In another application, performing the depolymerization reaction under pressure at a temperature above that of the alcohol allows for accelerated depolymerization rates and the recovery of the organocatalyst with no further heat input.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 16, 2015
    Applicant: International Business Machines Corporation
    Inventors: Robert D. Allen, Krishna M. Bajjuri, James L. Hedrick, Gregory Breyta, Carl E. Larson
  • Publication number: 20150068427
    Abstract: Provided is an optical film used for the optical compensation, in which additives are added to thereby have a good stability at high temperature and high humidity, a higher chromaticity, a higher Haze and a higher moisture resistance, as well as a small thickness direction retardation (Rth).
    Type: Application
    Filed: May 7, 2013
    Publication date: March 12, 2015
    Inventors: Won Yeob Kim, Myoung Lae Kim, Hyuk Jun Kim, Yong Gyun Cho, Min Joung Im, Yeong Min Jo, Seung Eon Lee, Hyo Shin Kwak
  • Publication number: 20150073005
    Abstract: To provide a composition for hair growth (hair growth agent) which has high hair growing effects and can be used for prevention or treatment of alopecia. The composition for hair growth comprises as an active ingredient at least one member selected from the group consisting of a compound represented by the formula (1) and a salt thereof. In the formula, R is a carboxy group or an alkoxycarbonyl group.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 12, 2015
    Applicants: ASAHI GLASS COMPANY, LIMITED, SANTEN PHARMACEUTICAL, CO., LTD.
    Inventors: Atsushi Shimazaki, Arata Yasuda, Yasushi Matsumura
  • Patent number: 8853275
    Abstract: A novel therapy regime/regimen for the treatment of acne related diseases includes administering a topical fixed-dose combination of a retinoid and an anti-bacterial agent, such as BPO, to a course of oral antibiotic therapy.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: October 7, 2014
    Assignee: Galderma Research & Development
    Inventors: Jean-Charles Dhuin, Nabil Kerrouche, Stéphanie Arsonnaud, Pascale Soto
  • Publication number: 20140228339
    Abstract: There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.
    Type: Application
    Filed: April 15, 2014
    Publication date: August 14, 2014
    Applicant: AstraZeneca AB
    Inventors: Stephen Connolly, Mark Richard Ebden, Iain Alastair Stewart Walters, Thomas Langer, Alan Robert Steven, Craig Robert Stewart, Paula Margaret Tomlin, Andrew John Williams
  • Patent number: 8802147
    Abstract: The present invention relates to biodegradable polymers (e.g., polyesters and polyester amides) derived from functionalized biologically active compounds that can provide site specific delivery of bioactive compounds upon biodegradation in a controlled manner.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: August 12, 2014
    Assignee: Bezwada Biomedical, LLC
    Inventor: Rao S Bezwada
  • Publication number: 20140213677
    Abstract: The present invention discloses polyester-polyether polyols suitable for blending with other polyols or other materials mutually compatible with the polyester polyols to achieve polyurethane and polyisocyanurate products. In particular the present invention discloses polyester-polyether polyols produced by the reaction of: 1) phthalic anhydride with an alcohol having a nominal functionality of 3 and a molecular weight of 90 to 500 under conditions to form a phthalic anhydride half-ester; and 2) alkoxylating the half-ester formed in step 1 to form a polyester-polyether polyol having a hydroxyl number of from 200 to 350; with the proviso when the alcohol is a polyether polyol, the polyether polyol contains at least 70 weight percent of polyoxypropylene.
    Type: Application
    Filed: September 10, 2012
    Publication date: July 31, 2014
    Applicant: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Jorge Jimenez, Pavel L. Shutov, William N. Felsted, II, Melissa M. Rose, Davide Micheletti
  • Patent number: 8765994
    Abstract: The present invention includes the use of pelorol, related compounds and pharmaceutical compositions thereof as modulators of SHIP 1 activity. This invention also provides novel terpene compounds capable of modulating SHIP 1 activity and methods of synthesis thereof.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: July 1, 2014
    Assignee: The University of British Columbia
    Inventors: Raymond Andersen, David E. Williams, Alice Mui, Christopher Ong, Gerald Krystal, Lu Yang
  • Publication number: 20140171444
    Abstract: The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the enzyme. The compounds may be phenyl- naphthyl-, or thienyl-substituted diketo acids and carboxylate derivatives thereof. Also provided are methods of treating tuberculosis or other pathophysiological conditions associated with a malate synthase enzyme with the inhibitory compounds and methods of in silico design of the inhibitory compounds. In addition, the present invention provides the inhibitory compounds designed by this method. Furthermore, three-dimensional X-ray crystal structures of the Mycobacterial malate synthase complexed with the inhibitory compounds are provided. Further still a method for stabilizing an aromatic or heteroaromatic diketo acid or its prodrug or close analog in solution by derivatizing at least the ortho position on the aromatic ring is provided.
    Type: Application
    Filed: March 3, 2014
    Publication date: June 19, 2014
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Joel S. Freundlich, James C. Sacchettini, Inna V. Kriger, Thomas R. Ioerger, Vijay Gawandi
  • Publication number: 20140099370
    Abstract: The present invention relates to biodegradable polymers (e.g., polyesters and polyester amides) derived from functionalized biologically active compounds that can provide site specific delivery of bioactive compounds upon biodegradation in a controlled manner.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 10, 2014
    Applicant: BEZWADA BIOMEDICAL, LLC
    Inventor: Rao S Bezwada
  • Patent number: 8664428
    Abstract: The present invention relates to a novel process for preparing substituted and unsubstituted (2,4-dimethylbiphenyl-3-yl)acetic acids and their esters of the formula (I) using homogeneous and heterogeneous palladium catalysts, and also the intermediates 4-tert-butyl-2,6-dimethylphenylacetic acid and 4-tert-butyl-2,6-dimethylmandelic acid, and to processes for their preparation.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: March 4, 2014
    Assignee: Bayer CropScience AG
    Inventors: Reiner Fischer, Thomas Himmler, Wolfgang Joerges, Werner Lindner, Wahed Ahmed Moradi
  • Publication number: 20140051882
    Abstract: The present invention discloses a method of purification of prostaglandins including fluorine atoms by using preparative HPLC. Tafluprost and Travoprost are prostaglandins including fluorine. The chemical structure of the impurities in crude Tafluprost and crude Travoprost also contain fluorine, therefore, the removal of the impurities is difficult. Purification by using preparative high performance liquid chromatography (HPLC) can achieve high-quality liquid bulk drugs.
    Type: Application
    Filed: February 13, 2013
    Publication date: February 20, 2014
    Applicant: EVERLIGHT USA, INC.
    Inventors: Chia-Chung TSAI, Chien-Yuh CHEN, Sen-Bau LIANG, Yu-Chi LO, Chi-Hsiang YAO
  • Patent number: 8653258
    Abstract: The present disclosure encompasses compounds and compositions that are useful as specific AI-2 antagonists for the control of bacterial quorum sensing. Although the AI-2 antagonists according to the present disclosure may not have bactericidal effect, their ability to attenuate virulence, drug resistance, and/or biofilm formation have therapeutic benefits. In addition, the AI-2 antagonists of the present disclosure can also be used as tools to probe bacterial AI-2 functions. The present disclosure also encompasses methods for inhibiting or attenuating microbial virulence, biofilm formation, and drug resistance. The methods are suitable for preventing bacteria from accruing and forming extensive biofilms that may be a health or hygiene hazard or a physical issue, such as in the blockage of water or fuel lines.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: February 18, 2014
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Binghe Wang, Nanting Ni, Junfeng Wang, Chung-Dar Lu, Han-Ting Chou, Minyong Li, Shilong Zheng, Yunfeng Cheng, Hanjing Peng
  • Publication number: 20130317249
    Abstract: The present invention provides a method for the purification of a prostaglandin by supercritical fluid chromatography, said method comprising the use of a stationary phase and a mobile phase comprising carbon dioxide, provided that when the stationary phase is unmodified silica gel, the prostaglandin is not luprostiol. The invention also provides prostaglandins obtainable by the method.
    Type: Application
    Filed: July 29, 2013
    Publication date: November 28, 2013
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Robert R. Hogan, Ronald Rossi
  • Patent number: 8586607
    Abstract: There is provided novel compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type II diabetes, hypertension, ketoacidosis, obesity, glucose intolerance, and hypercholesterolemia and related disorders associated with abnormally high or low plasma lipoprotein, triglyceride or glucose levels.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: November 19, 2013
    Assignee: Syddansk Universitet
    Inventors: Trond Ulven, Elisabeth Christiansen
  • Publication number: 20130267714
    Abstract: Compounds of the formula (I) in the form of a mixture of predominantly one diastereomer or in the form of pure diastereomers, Z1-Q-P*R0R1??(I), wherein: Z1 is a C-bonded, secondary phosphine group of the formula —P(R)2, wherein R is a hydrocarbon radical or O-atom(s)-containing heterohydrocarbon radical having 1 to 18 carbon atoms and optionally substituted by C1-C6-alkyl, trifluoromethyl, C1-C6-alkoxy, trifluoromethoxy, (C1-C4-alkyl)2-amino, (C6H5)3Si, (C1-C12-alkyl)3Si or halogen; Q is selected from the group consisting of: (i) an optionally substituted achiral aromatic group, wherein the achiral aromatic group is bonded directly to Z1 through a carbon atom of the achiral aromatic group and bonded directly to P*R0R1 through a carbon atom of the achiral aromatic group, and (ii) an optionally substituted C1-C4-alkylene group; P* is a chiral phosphorus atom; R0 is methyl; and R1 is a C-bonded optically enriched or optically pure chiral, mono- or polycyclic, nonaromatic hydrocarbon ring; and prepar
    Type: Application
    Filed: April 26, 2013
    Publication date: October 10, 2013
    Inventors: Benoit PUGIN, Matthias LOTZ, Heidi LANDERT, Adrian WYSS, Raphael AARDOOM, Bjorn GSCHWEND, Andreas PFALTZ, Felix SPINDLER
  • Publication number: 20130225822
    Abstract: The present invention relates to a chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof. The chiral spiro-pyridylamidophosphine compound is a compound having a structure of Formula (I), a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly characterized by having a chiral spiro-dihydro-indene skeleton in its structure. The chiral spiro-pyridylamidophosphine compound may be synthesized with optical active 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene or substituted 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene having a spiro-skeleton as chiral starting material. The chiral spiro-pyridylamidophosphine compound may be used as a chiral ligand in asymmetric hydrogenation of a carbonyl compound catalyzed by iridium, in which the reaction activity is very high, the amount of the catalyst may be 0.0001 mol %, and the enantioselectivity of the reaction is up to 99.9% ee.
    Type: Application
    Filed: November 18, 2011
    Publication date: August 29, 2013
    Inventors: Qilin Zhou, Jianhua Xie, Xiaoyan Liu, Jianbo Xie, Lixin Wang
  • Publication number: 20130217674
    Abstract: Compounds of structure (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2 and A are as defined herein are disclosed. Such compounds have enhanced water solubility and have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Enantioselective methods for preparation of compounds of structure (I), compositions comprising a compound of structure (I) in combination with a pharmaceutically acceptable carrier or diluents and methods of SHIP1 modulation by administration of such compounds to an animal in need thereof are also disclosed.
    Type: Application
    Filed: August 22, 2011
    Publication date: August 22, 2013
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Xiaoxia Wang, Labros George Meimetis, Matthew Bruce Nodwell, Raymond Andersen
  • Publication number: 20130211033
    Abstract: The present invention relates to a process for synthesizing a multifunctional compound, including the reaction of a compound of formula (II) with atmospheric or molecular oxygen, in the presence of at least one aldehyde of formula (III), and optionally in the presence of at least one catalyst or at least one radical initiator; wherein: R10, R20, R30, R40, R50, L2, R60, R7, R8, and R9 are as described in the claims. The invention also relates to the use of these compounds as monomers for the preparation of polyurethane. The invention also relates to the use of these compounds as monomers of polymers or of biopolymers.
    Type: Application
    Filed: October 27, 2011
    Publication date: August 15, 2013
    Applicants: MEURICE R&D ASBL, UNIVERSITE DE POITIERS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stefano Casciato, Yannick Pouilloux, Vincent Dubois
  • Publication number: 20130197260
    Abstract: The invention relates to improved process for the preparation of fesoterodine and its pharmaceutically acceptable salt, specifically fesoterodine fumarate of formula (1). The invention relates to solid state forms of a novel salt of fesoterodine and process for the preparation thereof. The invention also relates to highly pure fesoterodine fumarate substantially free of impurity X at RRT 1.37. The invention also provides solid particles of pure fesoterodine fumarate wherein 90 volume-percent of the particles (D90) have a size of higher than 200 microns.
    Type: Application
    Filed: August 25, 2011
    Publication date: August 1, 2013
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Kuldeep Natwarlal Jain
  • Patent number: 8481758
    Abstract: The present invention relates to an improved process for the production of prostaglandins and prostaglandin analogs. In particular, this invention relates to the production of prostaglandins of the PGF2?-series, including latanoprost, travoprost, and bimatoprost, which are active pharmaceutical ingredients used for the reduction of elevated intra-ocular pressure in patients with glaucoma and ocular hypertension.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: July 9, 2013
    Assignee: Sandoz AG
    Inventors: Martin Albert, Andreas Berger, Dominic De Souza, Kerstin Knepper, Hubert Sturm
  • Publication number: 20130071458
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Application
    Filed: May 9, 2012
    Publication date: March 21, 2013
    Inventors: Suseela Kanamathareddy, Karen J. Giroux
  • Publication number: 20130046013
    Abstract: Fatty acid conjugates of salicylate derivatives and compositions thereof are disclosed. Further disclosed are methods for treating various diseases comprising the administration of an effective amount of at least one compound according to the present disclosure.
    Type: Application
    Filed: January 20, 2011
    Publication date: February 21, 2013
    Inventors: Ragnar Hovland, Tore Skæret, Jenny Rosman
  • Publication number: 20130041142
    Abstract: [Object] An object of the present invention is to provide a human sweet taste receptor-acting sweet taste regulating substance to a sweet taste substance by which the advantageous effects such as improvement in a taste, saving of a sweetener, reduction in calorie, low caries etc. can be obtained by applying to various foods and beverages. [Solution] The sweet taste receptor-acting sweet taste regulating substance of the present invention is identified by measurement of a physiological response by a sweet taste substance, using a cultured cell strain which is allowed to express hT1R2 and hT1R3, and a G protein ? subunit, by transferring an expression construct obtained by inserting respective cDNAs encoding the hT1R2 and the hT1R3, and the G protein ? subunit into the same plasmid, into a 293 cell in which an FRT (Flippase Recognition Target) site has been incorporated into one place in a genome DNA.
    Type: Application
    Filed: September 8, 2010
    Publication date: February 14, 2013
    Inventors: Keiko Abe, Takumi Misaka, Satoshi Fujiwara
  • Patent number: 8361352
    Abstract: Chemical light producing systems and the chemiluminescent formulations contained therein are taught which exhibit reduced hydrolysis and thereby are characterized by an inherently long shelf-life and commercial viability. By replacing the typical oxalate ester, e.g. (bis{3,4,6-trichloro-2-[(pentoxy)carbonyl]phenyl}oxalate) with a branched chain oxalic acid ester represented by the general formula: wherein the group designated as R contains from 4-15 carbons, wherein the carbon of attachment of R to the oxygen is via a primary carbon, and wherein substructure A is composed of substituents selected from the group including alkyl chains, alkyl rings, aromatic rings and combinations thereof such that R is nonlinear, water hydrolysis of the oxalate ester is retarded. This retardation of the hydrolysis changes the storage constraints of the oxalate ester.
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: January 29, 2013
    Assignee: Cyalume Technologies, Inc.
    Inventors: Earl Cranor, Linda Jacob
  • Patent number: 8357819
    Abstract: The invention relates to a process for the synthesis of (Z)-3-[2-butoxy-3?-(3-heptyl-1-methylureido)biphenyl-4-yl]-2-methoxyacrylic acid of formula (I): and also to the process for the synthesis of the reaction intermediates of general formula (XII), and to the said compounds when R2 is chosen from the methyl, trifluoromethyl, phenyl and 4-tolyl radicals:
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: January 22, 2013
    Assignee: Galderma Research & Development
    Inventor: Jean-Guy Boiteau
  • Patent number: 8334035
    Abstract: Polyester polyols are produced by reacting terephthalic acid with a glycol corresponding to the formula H—(OCH2CH2)n—OH and an aliphatic dicarboxylic acid. These polyester polyols are particularly useful for the production of polyurethane) (PUR) and polyurethane/polyisocyanurate (PUR/PIR) foams for use in insulation applications.
    Type: Grant
    Filed: March 27, 2010
    Date of Patent: December 18, 2012
    Assignee: Bayer MaterialScience AG
    Inventors: Hartmut Nefzger, Erika Bauer, Uwe Kuenzel, Jürgen Schloβmacher, Lutz Brassat
  • Publication number: 20120289614
    Abstract: This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.
    Type: Application
    Filed: July 29, 2012
    Publication date: November 15, 2012
    Applicant: BEZWADA BIOMEDICAL, LLC
    Inventor: Rao S. Bezwada
  • Patent number: 8299288
    Abstract: Disclosed is a method for producing a compound represented by Formula (4), the method including Step I of adding a solution in which hydrogen chloride is dissolved in an alcohol, to a mixture containing an organic solvent and a compound represented by Formula (1), and Step II of mixing a compound obtained in Step I, represented by Formula (3), with water.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: October 30, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hajime Ishida, Masaji Hirota
  • Patent number: 8299119
    Abstract: Compounds having useful biological activity, particularly antioxidant and anti-inflammatory activity, derived from Centipeda cunninghamii, and biologically active derivatives thereof, pharmaceutical compositions comprising these compounds, and prophylactic and therapeutic use of the compounds.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: October 30, 2012
    Assignee: Bio-Active Export Pty. Ltd.
    Inventors: David Leach, Lesley Stevenson, Brigitte Gabriel, Karren Beattie
  • Patent number: 8278445
    Abstract: Preparation method of a compound of general formula (I) comprises the following steps: (1) a compound of general formula (II) reacts with a formylating agent in an aprotic solvent at a temperature between ?20° C. and 200° C. in the presence of a Lewis acid, then an organic base is added to promote the reaction to obtain an intermediate product; (2) the above intermediate product reacts with a methylating agent in the presence of an alkali at a temperature between ?20° C. and 100° C. to obtain the compound of formula (I).
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: October 2, 2012
    Assignee: Nutrichem Company Limited
    Inventors: Shangzhong Liu, Canxian Mu, Wenjun Wang, Jianwei Chen, Shuguang Wang
  • Publication number: 20120196740
    Abstract: Bi-functional cobalt-containing catalysts useful for making stereo specific compounds and compositions, along with methods of making, and uses thereof in the syntheses of optically pure ?-lactones from aldehydes and ketene are described. Precursors, intermediates, compositions, and particular features of the use if the compositions, such as high enantiomeric selectivity, high yield and low mole percent of catalyst useful are provided.
    Type: Application
    Filed: June 7, 2010
    Publication date: August 2, 2012
    Applicant: UNIVERSITY OF TOLEDO
    Inventor: Yun-Ming Lin
  • Publication number: 20120190809
    Abstract: To provide a fluorinated compound having an RF group with at most 6 carbon atoms, whereby a fluorinated polymer having a highly durable water/oil repellency can be produced, and an environmental load is little, and a fluorinated polymer having a highly durable water/oil repellency and presenting little environmental load, obtainable by polymerizing such a fluorinated compound. A fluorinated compound represented by the following formula (I) and its polymer: CH2?C(M)COO(CH2)nPhXPhZCrF2r+1??(I) (in the formula (I), M is a hydrogen atom, a methyl group or a halogen atom, n is an integer of from 0 to 2, Ph is a phenylene group, X is CH2O or OCH2, Z is a single bond, a C1-4 alkylene group containing an etheric oxygen atom, or COO(CH2)m (wherein m is an integer of from 1 to 4), and r is an integer of from 1 to 6).
    Type: Application
    Filed: March 30, 2012
    Publication date: July 26, 2012
    Applicant: Asahi Glass Company, Limited
    Inventor: Taiki HOSHINO
  • Publication number: 20120142805
    Abstract: The invention pertains to an oligomer or polymer substituted by one or more bisacylphosphine oxide moieties, characterized in that said bisacylphosphine oxide moiety is linked via the phosphorous atom, optionally via a spacer group, to the oligomer or polymer backbone; as well as to specifically functionalized bisacylphosphine oxides, suitable to prepare said polymers or oligomers.
    Type: Application
    Filed: June 29, 2010
    Publication date: June 7, 2012
    Applicant: BASF SE
    Inventors: Hansjorg Grutzmacher, Timo Ott, Kurt Dietliker
  • Publication number: 20120136164
    Abstract: The invention relates to a nanoparticulate material comprising long ultrathin metal nanowires, and to processes for making it. The nanoparticulate material may be used as a catalyst and, in the presence of a chiral modifier, can catalyse enantioselective reactions.
    Type: Application
    Filed: March 30, 2010
    Publication date: May 31, 2012
    Applicant: Agency for Science, Technology and Research
    Inventors: Jackie Y. Ying, Nandanan Erathodiyil, Hongwei Gu, Huilin Shao, Jiang Jiang
  • Publication number: 20120095114
    Abstract: This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.
    Type: Application
    Filed: September 23, 2011
    Publication date: April 19, 2012
    Applicant: BEZWADA BIOMEDICAL, LLC
    Inventor: Rao S. Bezwada
  • Publication number: 20120071465
    Abstract: The present invention relates to the compounds useful in the prevention and/or treatment of tumours. More specifically the present invention relates to inhibitors of the activity of the electron transport chains and/or the mitochondrial TCA cycle in glioma-initiating cells (GICs) for use in a method for preventing and/or treating tumours presenting glioma-initiating cells (GICs) in a subject who has undergone a prior removal of a tumour glioma bulk. The present invention further provides a pharmaceutical composition containing the inhibitors of the invention and a screening method for identifying the inhibitors of the invention.
    Type: Application
    Filed: May 20, 2010
    Publication date: March 22, 2012
    Inventors: Virginie Clement, Ivan Radovanovic
  • Publication number: 20120052228
    Abstract: Polyester polyols are produced by reacting terephthalic acid with a glycol corresponding to the formula H—(OCH2CH2)n—OH and an aliphatic dicarboxylic acid.
    Type: Application
    Filed: March 27, 2010
    Publication date: March 1, 2012
    Applicant: BAYER MATERIALSCIENCE AG
    Inventors: Hartmut Nefzger, Erika Bauer, Uwe Kuenzel, Jürgen Schlossmacher, Lutz Brassat
  • Publication number: 20120050391
    Abstract: An ink jet liquid composition which is used with an ink containing a pigment and which contains an ABC triblock polymer formed from an A block having an aryl group, a B block having a unit represented by the general formula (1), and a C block having a unit represented by the general formula (2), wherein an acid value of the polymer is 20 mgKOH/g or more and less than 150 mgKOH/g, the ratio of the number average molecular weight of the polymer to the acid value is 50 or more and 200 or less, the proportion of the A block in the polymer is 20.0 percent by mass or more and 80.0 percent by mass or less and is 5.0 times or more and 15.0 times or less the proportion of units derived from all acidic monomers contained in the polymer.
    Type: Application
    Filed: August 24, 2011
    Publication date: March 1, 2012
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Kenji Nishiguchi, Sachie Furukawa, Katsuhiro Hayashi
  • Publication number: 20120035224
    Abstract: The invention relates to compounds derived from betulin, and to the use thereof in plant pest control, particularly as antifeedants for butterfly larvae, beetles and snails. Further, the invention relates to novel betulin derivatives and methods for the production thereof either directly from betulin, or via intermediates derived therefrom.
    Type: Application
    Filed: June 1, 2007
    Publication date: February 9, 2012
    Applicant: Valtion teknillinen tutkimuskeskus
    Inventors: Sami Alakurtti, Jari Yli-Kauhaluoma, Taru Mäkelä, Salem Koskimies, Pia Bergström, Heikki Hokkanen, Ingeborg Menzler-Hokkanen
  • Publication number: 20120035388
    Abstract: This invention provides a platinum/carbon nanotube catalyst applicable to heterogeneous asymmetric hydrogenation, which is fabricated by supporting platinum on carbon nanotube carriers. The catalyst is prepared by the steps of: heating purified carbon nanotubes in nitric acid, filtering and washing the same with water until pH value of the filtrate becomes neutral, drying the carbon nanotubes; immersing the carbon nanotube carriers obtained in an aqueous chloroplatinic acid solution and carrying out ultrasonic treatment at room temperature; immersing the mixture of the carbon nanotubes and the aqueous chloroplatinic acid solution under stirring; drying the material by heating to 110° C. from room temperature and maintaining this temperature; grinding the product to fine powders, reducing the fine powders with an aqueous sodium formate solution under a heating condition, filtering and washing the product with deionized water, and drying the product.
    Type: Application
    Filed: May 11, 2010
    Publication date: February 9, 2012
    Applicant: Dalian Institute of Chemical Physics Chinese Academy of Sciences
    Inventors: Can Li, Zhijian Chen
  • Patent number: 8101095
    Abstract: The racemic and chiral compounds expressed by common formula 1 and formula 2: wherein the lateral substituents X1, X2, X3, X4, X5, X6, X7 and X8 in the benzene rings represent independently hydrogen and fluorine atoms, bridge group Z represent independently the single bond or COO, CH2CH2, CH2O and OCH2 group, substituent Y represents CH3, or CH2F, CHF2, CF3, C2H5 group, symbols n, m, r and t are independently integers of 1 to 8; symbols p and s signify independently number of 0 to 1 and its orthoconic antiferroelectric long helical pitch mixtures prepared by the methods 1) to the racemic components selected from compounds 1 are added chiral components selected from the compound of formula 1 and/or chiral components selected from the compounds of formula 2 and/or another optically active compounds with high helical twisting power, 2) to chiral compound 1 which helical pitches increases with the temperature increase is added chiral compound 1 which helical pitch decreases with temperature increase.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: January 24, 2012
    Assignee: Wojskowa Akademia Techniczna IM. Jaroslawa Dabrowskiego
    Inventors: Roman Slawomir Dabrowski, Krzysztof Ludwik Czuprynski, Przemyslaw Kula, Magdalena Zurowska, Wojciech Rejmer, Wiktor Piecek, Zbigniew Raszewski
  • Publication number: 20120016136
    Abstract: The invention concerns a new process for the preparation of prostaglandin derivatives, in particular prostaglandin F2? derivatives, for example bimatoprost, latanoprost and travoprost, the new intermediates of said process and their use in the preparation of prostagblandin derivatives.
    Type: Application
    Filed: February 18, 2010
    Publication date: January 19, 2012
    Inventors: Giancarlo Biffi, Alessandro D'Alfonso, Lazzaro Feliciani, Alessio Porta, Giovanni Vidari, Enrico Viscardi, Giuseppe Zanoni
  • Publication number: 20110282077
    Abstract: The object of the present invention is to solve the problems in the prior arts, and to find more improved reaction conditions for suppressing the racemization of the product and obtaining an optically active alcohol at a high optical purity. The inventors achieved to solve the above problems by using a solvent system that is capable of resolving both an asymmetric catalyst and a formate salt, allowing the hydrogen source and the asymmetric catalyst to be present in the same phase.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 17, 2011
    Applicant: Kanto Kagaku Kabushiki Kaisha
    Inventors: Taito Hatakeyama, Kunihiko Murata, Kunihiko Tsutsumi, Noriyuki Utsumi
  • Publication number: 20110245528
    Abstract: The invention relates to novel resolvin compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel resolvin compounds of the invention.
    Type: Application
    Filed: September 23, 2009
    Publication date: October 6, 2011
    Inventor: C. Eric Schwartz
  • Publication number: 20110237697
    Abstract: The invention relates to the production and use of polyester polyols, formed from at least one carboxylic acid hydride and ethylene glycol, wherein a specialized reaction control stustantially suppresses the formation of 1,4-dioxane from diethylene glycol.
    Type: Application
    Filed: October 24, 2009
    Publication date: September 29, 2011
    Applicant: Bayer MaterialScience AG
    Inventors: Hartmut Nefzger, Erika Bauer, Johannes Van de Braak, Jürgen Schlobmacher
  • Patent number: RE43372
    Abstract: Compounds having the general structure: which are useful for the treatment of a variety of diseases and conditions, such as bone disorders.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: May 8, 2012
    Assignee: Duke University
    Inventors: Mitchell Anthony deLong, David Lindsey Soper, John August Wos, Biswanath De