Sulfur Or Oxygen Bonded Directly To Phosphorus Patents (Class 568/14)
  • Patent number: 11326015
    Abstract: A method for making a cyanate ester resin includes reacting an arylorganometallic agent with a phosphorous halide in a solvent forming methoxy functionalized triphenylphosphines with one to six meta-methoxy groups. The methoxy functionalized triphenylphosphines with one to six meta-methoxy groups are reacted with an oxidizing agent forming a methoxy functionalized triphenylphosphine oxide including one to six meta-methoxy groups. The methoxy functionalized triphenylphosphine oxide is reacted with a dealkylating agent forming a hydroxy substituted triphenylphosphineoxide including one to six meta-hydroxyl groups. The hydroxy substituted triphenylphosphineoxide is reacted with cyanating reagent and a base forming a substituted triphenylphosphine oxide including one to six meta-cyanate groups. The substituted triphenylphosphine oxide is polymerized forming the cyanate ester resin.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: May 10, 2022
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventor: Matthew C. Davis
  • Patent number: 11220520
    Abstract: The present invention relates primarily to processes conducted in a continuously operated reactor for preparing particular phosphorus-containing ?-aminonitriles of the formulae (Ia) and (Ib) defined hereinafter from corresponding phosphorus-containing cyanohydrin esters and to the use thereof for preparation of glufosinate or of glufosinate salts. The present invention further relates to a process for producing glufosinate/glufosinate salts.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: January 11, 2022
    Assignee: BASF SE
    Inventors: Kilian Tellmann, Gunter Karig, Heike Ehrich, Michael Sebek
  • Patent number: 10487070
    Abstract: Subject-matter of the invention is a process for preparing intermediates useful in the synthesis of drugs, for example antifungal drugs, such as efinaconazole. Subject-matter of the invention are also such novel synthesis intermediates and the use thereof.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: November 26, 2019
    Assignee: OLSON S.P.A.
    Inventors: Giorgio Bertolini, Corrado Colli, Mara Sada, Federica Colombo
  • Patent number: 10388889
    Abstract: A heterocyclic compound and an organic light emitting device, the compound being represented by Formula 1:
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: August 20, 2019
    Assignee: SAMSUNG DISPLAY CO., LTD.
    Inventors: Heechoon Ahn, Soobyung Ko, Mieun Jun, Youngkook Kim, Seokhwan Hwang
  • Patent number: 9469662
    Abstract: The present invention relates to a process for preparing optically active bisphosphinylalkanes from the correspondingly substituted, racemic 1,2-diols. The optically active bisphosphinylalkanes which can be obtained in this way are suitable as ligands for preparing chiral transition metal catalysts.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: October 18, 2016
    Assignee: BASF SE
    Inventors: Christoph Jaekel, Rocco Paciello
  • Patent number: 9133222
    Abstract: Method produces polyprenyl phosphates of formula, where each isoprene unit contains 5 carbon atoms, W is ?-end isoprene, T is trans-isoprene, C is cis-isoprene, S is 2,3-dihydroisoprene, a=0-10, b=0-39, c=0-1, a+b+c=4-40, and X is of formula OPO3MM?, wherein M and M? are identical or different and are a hydrogen cation or monovalent inorganic or organic cation, or M and M? together are divalent inorganic or organic cation, the phosphorylation of the relevant polyprenol or a mixture of oligomer homologues, where X is hydroxyl group, using a substituted ammonium salt of phosphoric acid in presence of condensing agent, is carried out in a medium of first aprotic organic solvent; and a polyprenyl phosphate of mono- or disubstituted salts thereof with monovalent cations or in form of salts thereof with divalent cations is isolated by extraction and precipitation.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: September 15, 2015
    Assignee: OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU GAMAVETFARM ( OOO GAMAVETFARM
    Inventor: Leonid Leonidovich Danilov
  • Publication number: 20150141557
    Abstract: A stabilizer including a first component and a second component. The first component is a compound represented by the formula (1). The second component is a compound represented by the formula (2).
    Type: Application
    Filed: January 28, 2014
    Publication date: May 21, 2015
    Applicant: DOUBLE BOND CHEMICAL IND., CO., LTD.
    Inventors: Chiung-Ta Chen, Chih-Wei Lin, Ming-Yang Chien, En-Ching Wang, Chien-Liang Liu
  • Publication number: 20150141698
    Abstract: The invention relates to a method for producing tris(perfluoroalkyl)phosphine oxides and bis(perfluoroalkyl)phosphinic acids by reacting tris(perfluoroalkyl)difluorophosphorane or bis(perfluoroalkyl)trifluorophosphorane with non-metal oxides, metalloid oxides or organic compounds with basic oxygen residues.
    Type: Application
    Filed: June 4, 2013
    Publication date: May 21, 2015
    Applicant: Merck Patent GmbH
    Inventors: Nikolai (Mykola) Ignatyev, Karsten Koppe, Walter Frank
  • Publication number: 20150137084
    Abstract: Triptycene derivatives having symmetric or asymmetric substituents are provided. The triptycene derivatives of the present invention may be applied in phosphorescent lighting devices ranging from deep blue to red and may be applied as a host material, an electron transporting material or a hole transporting material. An OLED device is also herein disclosed.
    Type: Application
    Filed: May 19, 2014
    Publication date: May 21, 2015
    Applicant: National Tsing Hua University
    Inventors: Chien-Hong CHENG, Ho-Hsiu CHOU, Cheng-Chang LAI
  • Patent number: 9035016
    Abstract: A polymer composition for solar cell and flexible electronics devices, where the polymer is a p-type conducting polymer. The p-type polymer comprises a benzothiadiazole acceptor and indeno-fluorene donor. Further, a solar cell and flexible electronic device article may be made from the polymer.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: May 19, 2015
    Assignee: Saudi Basic Industries Corporation
    Inventors: Dwight Seferos, Brandon Djukic, Ahmed I. Abdelrahman
  • Patent number: 9012546
    Abstract: This invention relates to a process for producing compounds derived from 9,10-Dihydro-9-Oxa-10-Phosphaphenantrene-10-oxide (DOPO). In particular, the invention relates to producing DOPO-derived compounds by reacting DOPO with diol compounds in the presence of a catalyst. This invention also relates to DOPO derived composition containing a high melting point diastereomer. The DOPO derived compounds may be useful as flame-retardants.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: April 21, 2015
    Assignee: Albemarle Corporation
    Inventors: Qiang Yao, Junzuo Wang, Arthur G. Mack
  • Publication number: 20150065738
    Abstract: The present invention provides a phosphorous compound represented by general formula (1), and transition metal complexes containing such phosphorous compounds as ligands: wherein R1 to R7, A, B, Y, and Z have the same meanings as those defined in the specification.
    Type: Application
    Filed: August 22, 2014
    Publication date: March 5, 2015
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Naota YOKOYAMA, Yuji NAKAYAMA
  • Patent number: 8957236
    Abstract: The compounds represented by the following general formula have excellent properties as a charge transport material. In the formula, R1 to R3 represent a substituent, n1 and n2 indicate an integer of from 0 to 5, n3 indicates an integer of from 0 to 4, X represents a linking group of —O—, —S—, —SO2—, —CS—, —R4—, —C(R5)(R6)—, —PO(R7)—, —Si(R8)(R9)—, >PO—, >Si(R10)— or >Si<, m is an integer of from 2 to 4, R4 represents an aliphatic cyclic linking group, and R5 to R10 represent a hydrogen atom, an alkyl group, an aryl group, etc.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: February 17, 2015
    Assignee: Kyushu University National University Corporation
    Inventors: Qisheng Zhang, Chihaya Adachi, Shigeyuki Matsunami, Kei Sakanoue
  • Publication number: 20150031896
    Abstract: The present invention relates to the improvement of organic electroluminescent devices, in particular blue-emitting devices, by using compounds of the formula (1) as dopants in the emitting layer.
    Type: Application
    Filed: October 2, 2014
    Publication date: January 29, 2015
    Inventors: Horst Vestweber, Holger Heil, Philipp Stoessel, Arne Buesing, Amir Hossain Parham, Rocco Fortte
  • Patent number: 8912124
    Abstract: The invention relates to derivatives of (1-cyanocyclopropyl)phenylphosphinic acid of the formula (I) and to salts thereof, of the formula (II), for enhancing stress tolerance in plants to abiotic stress, preferably to drought stress, especially for enhancing plant growth and/or for increasing plant yield.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: December 16, 2014
    Assignee: Bayer Cropscience AG
    Inventors: Lothar Willms, Hans-Joachim Zeiβ, Marco Busch, Christopher Hugh Rosinger, Ines Heinemann, Isolde Häuser-Hahn, Martin Jeffrey Hills, Pascal Von Koskull-Döring
  • Patent number: 8895775
    Abstract: It is provided a method for preparing conjugated diene phosphonate compounds with high reactivity, which can be used to prepare a variety of phosphonate-bearing conjugated dienes. Some of those dienes will become reactive monomers to make polymers and co-polymers.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: November 25, 2014
    Assignee: Rhodia Operations
    Inventors: Zhaoqing Liu, Floryan De Campo
  • Publication number: 20140343203
    Abstract: Use of an atmospheric plasma for the surface treatment of inorganic particles selected from the group consisting of particles of metal oxides, particles of metal carbonates, particles of metal sulfates, particles of metal phosphates, acicular particles, platy particles and fibrous particles,with a fluorine-containing precursor.
    Type: Application
    Filed: December 5, 2012
    Publication date: November 20, 2014
    Inventors: Hans Edouard Miltner, Eliana Ieva, Valeriy Kapelyushko
  • Patent number: 8846922
    Abstract: The present invention relates to functionalized fluoroalkylfluorophosphate salts, in particular as ionic liquids, to the preparation thereof and to the use thereof.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: September 30, 2014
    Assignee: Merck Patent GmbH
    Inventors: Berthold Theo Hoge, Anne Julia Bader, Nikolai Mykola Ignatyev, Michael Schulte, Wolfgang Hierse, Waldemar Wiebe, Helge Willner
  • Patent number: 8809487
    Abstract: The present disclosure relates to a process for the synthesis of a conducting polymer comprising a benzothiadiazole acceptor and indeno-fluorene donor of formula [IV].
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: August 19, 2014
    Assignee: Saudi Basic Industries Corporation
    Inventors: Dwight Seferos, Brandon Djukic
  • Patent number: 8796487
    Abstract: An improved process for production of dialkyldithiophosphinic acid including sulfurizing a purified dialkylphosphinic acid by: reacting a hypophosphorous acid or salt with a stoichiometric excess of an alpha olefin in the presence of a free radical initiator to form a reaction product comprising monoalkylphosphinic acid and dialkylphosphinic acid; adding sufficient aqueous base to the reaction product to i) form the salts of the phosphinic acids, and ii) establish an aqueous phase and an organic phase, wherein a monoalkylphosphinic acid solubilizes into an aqueous phase; separating the organic phase from the aqueous phase; acidifying the organic phase and removing the olefin from the organic phase; isolating the purified dialkylphosphinic acid product; and sulfurizing the purified dialkylphosphinic acid product to form a dialkydithiophosphinic acid.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: August 5, 2014
    Assignee: Rhodia Operations
    Inventors: Leo Zhaoqing Liu, Gary Woodward
  • Patent number: 8772549
    Abstract: Disclosed is a method for making a diphosphite of Structure I,
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: July 8, 2014
    Assignee: INVISTA North America S.à r.l.
    Inventors: Joachim C. Ritter, Thomas E. Vos
  • Patent number: 8764914
    Abstract: Aqueous media for quenching metal substrates are provided and contain (i) a polyvinylpyrrolidone/polyvinylcaprolactam copolymer and (ii) one or more of a second polymer, which is selected from (a) a substituted oxazoline polymer; (b) a poly(oxyethylene-oxyalkylene) glycol; or (c) a polyvinylpyrrolidone polymer. The quenching bath provides reduced cooling rates through the martensite temperature ranges. Also provided are processes for quenching metal substrates using these quenching media.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: July 1, 2014
    Assignee: Houghton Technical Corp.
    Inventors: Laura Gunsalus, Joseph F. Warchol
  • Patent number: 8735629
    Abstract: A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: May 27, 2014
    Assignee: Chromafora AB
    Inventors: Gaston Laven, Martin Kullberg
  • Patent number: 8735628
    Abstract: Processes for alkylating hydroxyaryl compounds by reacting a hydroxyaryl with at least one olefin of a complex hydrocarbon stream. The complex hydrocarbon stream preferably comprises a fraction of a cracked hydrocarbon feed stream or the reaction products of a dehydrogenation of a paraffinic feedstock. The olefin of the complex hydrocarbon stream is preferably a branched olefin, e.g., isobutylene or isoamylene. The alkylated compositions are suitable for forming liquid phosphite compositions.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: May 27, 2014
    Assignee: Addivant USA LLC
    Inventors: Jonathan S. Hill, Maurice Power, Paul Stott, Peter Smith
  • Publication number: 20140135530
    Abstract: The compounds represented by the following general formula have excellent properties as a charge transport material. In the formula, R1 to R3 represent a substituent, n1 and n2 indicate an integer of from 0 to 5, n3 indicates an integer of from 0 to 4, X represents a linking group of —O—, —S—, —SO2—, —CS—, —R4—, —C(R5)(R6)—, —PO(R7)—, —Si(R8)(R9)—, >PO—, >Si(R10)— or >Si<, m is an integer of from 2 to 4, R4 represents an aliphatic cyclic linking group, and R5 to R10 represent a hydrogen atom, an alkyl group, an aryl group, etc.
    Type: Application
    Filed: June 22, 2012
    Publication date: May 15, 2014
    Applicant: KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION
    Inventors: Qisheng Zhang, Chihaya Adachi, Shigeyuki Matsunami, Kei Sakanoue
  • Publication number: 20140091295
    Abstract: The present invention relates to new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission and containing at least one element of atomic number greater than 20, and for their use in organic electronic components such as electroluminescent elements and displays.
    Type: Application
    Filed: October 14, 2013
    Publication date: April 3, 2014
    Applicant: Merck Patent GmbH
    Inventors: Heinrich Becker, Anja Gerhard, Philipp Stoessel, Horst Vestweber
  • Patent number: 8648202
    Abstract: The invention relates to bis(perfluoroalkyl)phosphinous acids, bis(perfluoroalkyl)thiophosphinous acids and derivatives, the synthesis thereof and the use thereof, in particular for the synthesis of air-stable metal complexes for catalytic processes.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: February 11, 2014
    Assignee: Merck Patent GmbH
    Inventors: Berthold Hoge, Anne Julia Bader, Boris Kurscheid, Nikolai (Mykola) Ignatyev, Emil Ferdinand Aust
  • Patent number: 8609901
    Abstract: Disclosed is a method for making a diphosphite of Structure I,
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: December 17, 2013
    Assignee: Invista North America S.A R.L.
    Inventors: Joachim C. Ritter, Thomas E. Vos
  • Publication number: 20130303761
    Abstract: The present invention relates to novel protein modulators capable of altering function of the mutant CFTR protein and their use for treating diseases associated with CFTR protein malfunction. The invention provides compositions, pharmaceutical preparations and methods of correcting the cellular alteration of a mutant CFTR protein wherein the CFTR mutation is a mutation AF508-CFTR, or another mutation of class II.
    Type: Application
    Filed: June 20, 2011
    Publication date: November 14, 2013
    Applicant: INSTYTUT BIOCHEMII I BIOFIZYKI PAN
    Inventors: Norbert Odolczyk, Piotr Zielenkiewicz, Grzegorz Wieczorek, Aleksander Edelman, Danielle Tondelier, Janine Fritsch
  • Publication number: 20130287671
    Abstract: Embodiments of the present disclosure provide for multimetallic assemblies, methods of making a multimetallic assembly, methods of oxidizing water, methods of O-atom transfer catalysis, and the like.
    Type: Application
    Filed: April 25, 2013
    Publication date: October 31, 2013
    Inventors: Leslie Justin Murray, Gary Louis Guillet, Gianna Nadine Di Francesco, Jesse B. Gordon
  • Patent number: 8541612
    Abstract: The present invention relates to unsaturated diphosphine monoxides, to a process for preparation thereof and to the use thereof as flame retardants.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: September 24, 2013
    Assignee: BASF SE
    Inventors: Alexander Tishkov, Klemens Massonne
  • Patent number: 8536094
    Abstract: Herbicide combinations (A)+(B), if appropriate in the presence of safeners, with an effective content of (A) broad-spectrum herbicides from the group (A1) glufosinate (salts) and related compounds (A2) glyphosate (salts) and related compounds such as sulfosate, (A3) imidazolinones such as imazethapyr, imazapyr, imazaquin, imazamox or their salts and (A4) herbicidal azoles from the group of the protoporphyrinogen oxidase inhibitors (PPO inhibitors) and (B) one or more herbicides from the group consisting of (B0) one or more structurally different herbicides from the abovementioned group (A) or (B1) foliar- and soil-acting herbicides effective against selectively in rice monocotyledonous and dicotyledonous harmful plants (residual action) or (B2) herbicides which are effective selectively in rice against dicotyledonous harmful plants and/or sedges, and/or (B3) foliar-acting herbicides which are effective selectively in rice against monocotyledonous harmful plants, and/or (B4) foliar- and soil-acting herbi
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: September 17, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Erwin Hacker, Hermann Bieringer, Lothar Willms
  • Publication number: 20130193382
    Abstract: The present invention relates to compounds of the formula (I) and to the use thereof in electronic devices. The invention furthermore relates to electronic devices, preferably organic electroluminescent devices (OLEDs), comprising one or more com-pounds of the formula (I). The invention again furthermore relates to the preparation of compounds of the formula (I) and to formulations comprising one or more compounds of the formula (I).
    Type: Application
    Filed: September 6, 2011
    Publication date: August 1, 2013
    Applicant: MERCK PATENT GmbH
    Inventors: Arne Buesing, Thomas Eberle, Irina Martynova, Teresa Mujica-Fernaud
  • Publication number: 20130197228
    Abstract: The present invention relates to functionalised fluoroalkylfluorophosphate salts, in particular as ionic liquids, to the preparation thereof and to the use thereof.
    Type: Application
    Filed: August 30, 2011
    Publication date: August 1, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Berthold Theo Hoge, Anne Julia Bader, Nikolai Mykola Ignatyev, Michael Schulte, Wolfgang Hierse, Waldemar Wiebe, Helge Willner
  • Patent number: 8471067
    Abstract: A process for the stereoselective preparation of a P-chiral four-co-ordinated phosphorus compound, the process comprising reacting a first reactant selected from the group consisting of a chiral alcohol, chiral amine or chiral thiol, with a second reactant comprising a P-chiral three-co-ordinated phosphorus compound, in the presence of an electrophile.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: June 25, 2013
    Assignee: University College Dublin
    Inventors: Declan Gilheany, Shane B. Robinson, Enda Bergin, Denise M. Walsh, Audrius Rimkus, Eoin F. Clarke, Brian G. Kelly, Eoghan M. McGarrigle, Colm P. O'Mahony, Cormac T. O'Connor
  • Patent number: 8426647
    Abstract: A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: April 23, 2013
    Assignee: Chromafora AB
    Inventors: Gaston Laven, Martin Kullberg
  • Patent number: 8377188
    Abstract: Disclosed is a polyfluoroalkylphosphonic acid oxyalkylene ester of the formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)[O(RO)mR?]d(OH)2-d (RO is a C2-C6 linear or branched oxyalkylene group, R? is a hydrogen atom or a C1-C20 alkyl group or aralkyl group, n is 1 to 6, a is 1 to 4, b is 1 to 3, c is 1 to 3, d is 1 or 2, and m is 1 to 100), which is a compound having a perfluoroalkyl group containing 6 or less carbon atoms and referred to as having low bioaccumulation potential, and exhibiting, when used as an active ingredient of a mold-releasing agent, mold release performance equivalent to that of a compound having a perfluoroalkyl group containing 8 or more carbon atoms. This compound is produced by subjecting a polyfluoroalkylphosphonic acid of the formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)(OH)2 and a polyalkyleneglycol or a monoether thereof of the formula: HO(RO)mR? to a condensation reaction.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: February 19, 2013
    Assignee: Unimatec Co., Ltd.
    Inventors: Yoshiyama Kaneumi, Seiichiro Murata, Katsuyuki Sato
  • Patent number: 8378157
    Abstract: The invention relates to a process for the preparation of bis(fluoroalkyl)phosphinyl chlorides or fluoroalkylphosphonyl dichlorides by reaction of the corresponding bis(fluoroalkyl)phosphinic acid or fluoroalkylphosphonic acid with aryltetrachlorophosphorane as chlorinating agent.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: February 19, 2013
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Nikolai (Mykola) Ignatyev, Dana Bejan, Helge Willner, Emil Aust
  • Patent number: 8357822
    Abstract: There is provided a process capable of preventing the adhesion of a catalyst to an evaporator in a step of separating a chlorophosphite as a target substance from a reaction liquid by evaporation. The process includes a first step of allowing phosphorus trichloride and a phosphorous acid triester represented by (RO)3P to react in the presence of a catalyst having a viscosity at 80° C. of 100 mPa·s or lower to produce a chlorophosphite represented by RO(R?)PCl, and a second step of vaporizing a reaction liquid containing the chlorophosphite obtained in the first step, in a short time, to separate the catalyst.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: January 22, 2013
    Assignee: Nippon Chemical Industrial Co., Ltd.
    Inventors: Kentaro Sasaki, Katsuhiko Tsunashima, Tadashi Saito, Yoshifusa Hara
  • Publication number: 20120330063
    Abstract: The invention relates to a process for the preparation of tris(perfluoroalkyl)phosphine oxides by reaction of tris(perfluoroalkyl)difluorophosphorane with alkaline-earth metal oxides, alkaline-earth metal carbonates, zinc oxide, copper(I) oxide, copper(II) oxide, silver oxide, mercury(II) oxide, cadmium oxide or cadmium carbonate
    Type: Application
    Filed: February 17, 2011
    Publication date: December 27, 2012
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Nikolai Mykola Ignatyev, Waldemar Wiebe, Helge Willner
  • Publication number: 20120322775
    Abstract: This invention discloses 3-desoxy-2-methylene-19-nor-vitamin D analogs, and specifically (20S)-3-desoxy-2-methylene-1?,25-dihydroxy-19-nor-vitamin D3 and (20R)-3-desoxy-2-methylene-1?,25-dihydroxy-19-nor-vitamin D3 as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to monocytes thus evidencing use as anti-cancer agents especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also exhibit relatively high calcemic activity evidencing use in the treatment of bone diseases.
    Type: Application
    Filed: June 13, 2012
    Publication date: December 20, 2012
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hector F. DeLuca, Lori A. Plum, Rafal R. Sicinski, Izabela Sibilska, Margaret Clagett-Dame
  • Patent number: 8318705
    Abstract: The invention relates to nitroso derivatives including carboxylic acid and phosphoric acid esters of hydroxy nitroso compounds that donate nitroxyl (HNO) under physiological conditions. The compounds and compositions of the invention are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure, ischemia/reperfusion injury and cancer.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: November 27, 2012
    Assignee: Cardioxyl Pharmaceuticals, Inc.
    Inventors: Lisa M. Frost, Stephen M. Courtney, Frederick A. Brookfield, Vincent J. Kalish
  • Patent number: 8313573
    Abstract: Disclosed is a mold-releasing agent comprising, as active ingredients, a polyfluoroalkylphosphonic acid represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)(OH)2 (n: an integer of 1 to 6, a: an integer of 1 to 4, b: an integer of 1 to 3, c: an integer of 1 to 3), or a salt thereof and a polyfluoroalkylphosphonic acid oxyalkylene ester represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)[O(RO)mR?]d(OH)2?d (RO: a C2-C6 linear or branched oxyalkylene group, R?: a hydrogen atom, a C1-C20 alkyl group, or aralkyl group, n: an integer of 1 to 6, a: an integer of 1 to 4, b: an integer of 1 to 3, c: an integer of 1 to 3, d: an integer of 1 or 2, m: an integer of 1 to 100).
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: November 20, 2012
    Assignee: Unimatec Co., Ltd.
    Inventors: Yoshiyama Kaneumi, Seiichiro Murata, Katsuyuki Sato
  • Patent number: 8212073
    Abstract: This invention relates to flame barrier compositions as well as a method for the preparation of the flame barrier compositions formed from a flame retardant composition and water. A protective barrier comprises a flame barrier composition or a flame barrier polymer on top of a layer or sandwiched between two or more layers of glass, wood, paper, polymer films, and other layered materials as well as mixtures of layers.
    Type: Grant
    Filed: November 29, 2004
    Date of Patent: July 3, 2012
    Inventor: Robert Valentine Kasowski
  • Patent number: 8193384
    Abstract: The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, ?-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: June 5, 2012
    Assignee: Board of Governors for Higher Education, State of Rhode Island and Providence Plantation
    Inventors: Keykavous Parang, Yousef Ahamdibeni
  • Publication number: 20120108849
    Abstract: A polyfluoroalkylphosphonic acid ester represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)(OR)2 (R is an alkyl group having 1 to 4 carbon atoms, n is an integer of 1 to 6, a is an integer of 1 to 4, b is an integer of 1 to 3, and c is an integer of 1 to 3) is produced by a process of reacting a polyfluoroalkyl iodide represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cI with a trialkyl phosphite represented by the general formula: P(OR)3 or by a process of reacting a polyfluoro-1-alkene represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)bCH?CH2 with a dialkyl phosphite represented by the general formula: (RO)2P(O)H.
    Type: Application
    Filed: June 23, 2010
    Publication date: May 3, 2012
    Applicant: UNIMATEC CO., LTD.
    Inventors: Seiichiro Murata, Katsuyuki Sato
  • Patent number: 8134021
    Abstract: The Phosphorus-containing bisphenols and preparing method thereof are disclosed. A method for producing the phosphorus-containing bisphenol of the formula (1) includes reacting compounds respectively defined by a formula (a), (b), (c) and an acid catalyst to yield compounds of phosphorus-containing bisphenol.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: March 13, 2012
    Assignees: National Chunghsing University, Chang Chun Plastics Co., Ltd
    Inventors: Ching-Hsuan Lin, Chia-Wei Chang, Tsung-Li Lin, Kuen-Yuan Hwang, An-Pang Tu, Fang-Hsien Su
  • Patent number: 8119617
    Abstract: The present invention relates to compounds of formula wherein the residues have various meanings and their use as pharmaceuticals.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: February 21, 2012
    Assignee: Novartis AG
    Inventors: Karl Baumann, Andreas Billich, Berndt Oberhauser
  • Publication number: 20110307074
    Abstract: This invention relates to biomaterials, said biomaterials for use in methods to control and/or induce bone growth. Particularly, the invention relates to macroporous calcium phosphate biomaterials pre-loaded with certain amounts of osteoclastic activity inhibitors for use in methods to control and/or induce bone growth in primates.
    Type: Application
    Filed: July 15, 2011
    Publication date: December 15, 2011
    Applicants: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG, MEDICAL RESEARCH COUNCIL OF SOUTH AFRICA
    Inventors: Ugo Ripamonti, Carlo Ferretti
  • Publication number: 20110245386
    Abstract: The invention relates to a method for producing mixed-substituted dialkyiphosphinic acids, esters, and salts, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to obtain an alkylphosphonous acid, the salt or ester (II) thereof, b) the obtained alkylphosphonous acid, the salt or ester (II) thereof is reacted with an olefin (IV) in the presence of a catalyst B to obtain the mixed-substituted dialkylphosphinic acid derivative (III), wherein R1, R2, R3, R4, R11, R12, R13, R14 are identical or different from each other and independently represent, inter alia, H, C1-C18-alkyl, C6-C18-aryl, C6-C18-aralkyl, C6-C18-alkylaryl, X represents H, C1-C18-alkyl, C8-C18-aryl, C6-C18-aralkyl, C8-C18-alkylaryl, Mg, Ca, Al, Sb, Sn, Ge, Ti, Fe, Zr, Zn, Ce, Bi, Sr, Mn, Cu, Ni, Li, Na, K and/or a protonated nitrogenous base, catalyst A represents transition metals and/or transition metal compounds and/or catalyst systems composed of a transition metal and/or a transit
    Type: Application
    Filed: October 6, 2009
    Publication date: October 6, 2011
    Applicant: CLARIANT FINANCE (BVI) LIMITED
    Inventors: Michael Hill, Werner Krause, Martin Sicken