Sulfur Or Oxygen Containing Patents (Class 568/13)
  • Patent number: 9617290
    Abstract: Bisphosphites having an outer naphthyl-phenyl unit.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: April 11, 2017
    Assignee: Evonik Degussa GmbH
    Inventors: Katrin Marie Dyballa, Robert Franke, Dirk Fridag, Armin Boerner, Detlef Selent
  • Patent number: 9447128
    Abstract: A method for preparing trishydroxymethyl phosphine from tetrakishydroxymethyl phosphonium salt, the method including at least the steps of continuously feeding a first reaction chamber with, from one hand, at least one tetrakishydroxymethyl phosphonium salt and, from another hand, at least one base, under conditions suitable for a reaction of the tetrakishydroxymethyl phosphonium salt(s) with the base(s), to form a mixture of trishydroxymethyl phosphine and formaldehyde; and continuously removing the formaldehyde.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: September 20, 2016
    Assignee: MAGPIE POLYMERS
    Inventors: Steven Van Zutphen, Vladica Bocokic
  • Patent number: 9174905
    Abstract: A process for the telomerization of butadiene comprises reacting 1,3-butadiene and an alkanol, in the presence of a catalyst promoter and an alkoxydimerization catalyst comprising a Group VIII transition metal and a triarylphosphine ligand, which includes one phenyl that is mono-ortho-alkoxy substituted and at least one other phenyl including at least one substituent that withdraws electrons from the phosphorus atom. The product includes an alkoxy-substituted octadiene, which may then be used to produce 1-octene. The catalyst shows improved stability, activity and selectivity toward the alkoxy-substituted octadiene.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: November 3, 2015
    Assignee: Dow Global Technologies LLC
    Inventors: John R. Briggs, Jasson T. Patton, Daryoosh Beigzadeh, Peter M. Margl, Henk Hagen, Sonet Vermaire-Louw
  • Patent number: 8981123
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: March 17, 2015
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai
  • Publication number: 20150065738
    Abstract: The present invention provides a phosphorous compound represented by general formula (1), and transition metal complexes containing such phosphorous compounds as ligands: wherein R1 to R7, A, B, Y, and Z have the same meanings as those defined in the specification.
    Type: Application
    Filed: August 22, 2014
    Publication date: March 5, 2015
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Naota YOKOYAMA, Yuji NAKAYAMA
  • Publication number: 20150025280
    Abstract: A catalytic system for reductive carbonylation of an alcohol that includes a rhodium complex, an iodide-containing catalyst promoter, and a supporting phosphorus-containing bidentate ligand for the rhodium complex containing at least one aromatic substituent covalently attached to at least one phosphorus of the supporting phosphorus-containing bidentate ligand in an ortho position with an alkoxy substituent or an aryloxy substituent.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 22, 2015
    Applicant: Dow Global Technologies LLC
    Inventors: Thomas P. Clark, Heather A. Spinney, Jason MacDonald, Clark H. Cummins, Jerzy Klosin, John R. Briggs
  • Patent number: 8871916
    Abstract: A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diazo-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl triazene which can be converted thermally or by addition of base to form the diazo-compound or the acyl triazene can be isolated. The method is particularly useful for conversion of azides carrying one or more electron withdrawing groups to diazo-compounds. The method can be carried out in aqueous medium under mild conditions and is particularly useful for conversion of azido sugars to diazo-compounds and diazonium salts thereof under physiological conditions. Tertiary phosphine reagents, particularly those that are water-soluble, and precursors for preparation of the reagents are provided.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: October 28, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald Thaddeus Raines, Eddie Leonard Myers
  • Publication number: 20140296539
    Abstract: A compound represented by the following General Formula (1): where R1 represents a protective group for a hydroxyl group or a hydrogen atom, and R2 represents a methyl group or an ethyl group.
    Type: Application
    Filed: June 11, 2014
    Publication date: October 2, 2014
    Inventors: Masakatsu SHIBASAKI, Naoya KUMAGAI
  • Publication number: 20140288210
    Abstract: A resin composition includes a resin selected from a polylactic acid resin and a polycarbonate resin as a matrix resin, and surface-treated red phosphorus, wherein the surface-treated red phosphorus is contained in an amount of 10 parts by weight to 40 parts by weight, based on 100 parts by weight of the polylactic acid resin or the polycarbonate resin.
    Type: Application
    Filed: October 18, 2013
    Publication date: September 25, 2014
    Applicant: FUJI XEROX CO., LTD.
    Inventor: Akira IMADA
  • Publication number: 20140142325
    Abstract: Novel P-chirogenic organophosphorus compounds of general formula (I), a process for the synthesis of the compounds of formula (I), and intermediate products of general formulae (II), (III) and (IV), as shown below, are involved in the synthesis of compounds (I). Metal complexes including compounds (I) as ligands are also described. The novel compounds and complexes are useful in asymmetric catalysis by transition metal complexes or organocatalysis, especially for asymmetric hydrogenation or allylation. Compounds of general formula (I) may be useful as agrochemical and therapeutic substances, or as reagents or intermediates for fine chemistry.
    Type: Application
    Filed: July 10, 2012
    Publication date: May 22, 2014
    Applicant: Centre National de la Recherche Scientifique(CNRS)
    Inventors: Sylvain Juge, Jerome Bayardon, Emmanuelle Remond, Hugo Laureano, Jean-Christophe Henry, Frederic Leroux, Francoise Colobert
  • Publication number: 20140114090
    Abstract: The present invention relates to ligands and catalyst systems for the hydroformylation of short and long chain olefins, preferably for the hydroformylation of ally alcohol producing 4-hydroxybutyraldehyde. The ligands disclosed herein are all-trans phosphinomethyl-cyclobutane ligands, such as, for example, all-trans-1,2,3, 4-tetra[bis-(3,5-xylyl)phosphinomethyl]-cyclobutane. The catalyst systems comprise these all-trans phosphinomethyl-cyclobutane ligands in combination with an organometallic rhodium complex such as, e.g., (acctylacetonato)-dicarbonyl-rhodium (I). The ligands and catalyst systems of the present invention may be employed in the hydroformylation of olefins, in particular in the hydroformylation of allylalcohol, and provide improved selectivity and high reaction yields.
    Type: Application
    Filed: May 25, 2012
    Publication date: April 24, 2014
    Applicant: UMICORE AG & CO. KG
    Inventor: Dieter Arlt
  • Patent number: 8647780
    Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, 0, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FXI0)N—(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: February 11, 2014
    Assignee: Acep Inc.
    Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
  • Patent number: 8557020
    Abstract: A compound represented by General Formula (1) below, where R denotes a C1-C10 hydrocarbon group, Z denotes any one of a sulfide group, a sulfinyl group and a sulfonyl group, and n denotes an integer of 4 to 8 is described. A method for extracting metals and a metal recovery method using a metal extractant comprising the compound represented by General Formula (1) are also described.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: October 15, 2013
    Assignees: Dowa Holdings Co., Ltd., Akita University
    Inventors: Fumio Hamada, Chun-Bin Li, Yoshihiko Kondo
  • Publication number: 20130261342
    Abstract: A process for the telomerization of butadiene comprises reacting 1,3-butadiene and an alkanol, in the presence of a catalyst promoter and an alkoxydimerization catalyst comprising a Group VIII transition metal and a triarylphosphine ligand, which includes one phenyl that is mono-ortho-alkoxy substituted and at least one other phenyl including at least one substituent that withdraws electrons from the phosphorus atom. The product includes an alkoxy-substituted octadiene, which may then be used to produce 1-octene. The catalyst shows improved stability, activity and selectivity toward the alkoxy-substituted octadiene.
    Type: Application
    Filed: December 14, 2011
    Publication date: October 3, 2013
    Applicant: Dow Global Technologies LLC
    Inventors: John R. Briggs, Jasson T. Patton, Daryoosh Beigzadeh, Peter M. Margl, Henk Hagen, Sonet Vermaire-Louw
  • Patent number: 8518915
    Abstract: The invention relates to pharmacology and medicine, in particular to a class of mitochondrially-addressed compounds which can be used in the pharmaceutical compositions of medicinal agents (preparations) for preventing and treating cardiovascular diseases and diseases and pathological conditions caused by disturbed blood circulation or oxygen supply to tissues and organs.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: August 27, 2013
    Assignee: Mitotech SA
    Inventors: Maxim Vladimirovich Skulachev, Vladimir Petrovich Skulachev
  • Publication number: 20130217899
    Abstract: The present invention relates to processes for the preparation of (2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (Fingolimod) and pharmaceutically acceptable salts thereof, and intermediates formed in such processes.
    Type: Application
    Filed: October 27, 2011
    Publication date: August 22, 2013
    Applicant: MAPI PHARMA LTD.
    Inventors: Ehud Marom, Michael Mizhiritskii, Shai Rubnov
  • Publication number: 20130184479
    Abstract: The present disclosure relates to biaryl diphosphine ligands of the formula (B), processes for the production of the ligands and the use of the ligands in metal catalysts for asymmetric synthesis. The disclosure also relates to intermediates used for the production of the biaryl diphosphine ligand.
    Type: Application
    Filed: September 9, 2011
    Publication date: July 18, 2013
    Applicant: KANATA CHEMICAL TECHNOLOGIES INC.
    Inventors: Kamaluddin Abdur-Rashid, Wenli Jia, Shuiming Lu, Rongwei Guo, Xuanhua Chen, Dino Amoroso
  • Patent number: 8404758
    Abstract: The invention provides methods for inducing reversible chain cleavage of polymer chains in a crosslinked polymeric material. Reversible cleavage of the polymer backbone is capable of relieving stress in the polymeric material as the bonds reform in a less stressed state. The invention also provides methods for making polymeric materials capable of reversible chain cleavage, materials made by the methods of the invention, and linear monomers containing reversible chain cleavage groups which are useful in the materials and methods of the invention.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: March 26, 2013
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Christopher N. Bowman, Timothy F. Scott
  • Publication number: 20130012725
    Abstract: A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.
    Type: Application
    Filed: March 30, 2011
    Publication date: January 10, 2013
    Applicant: CHROMAFORA AB
    Inventors: Gaston Laven, Martin Kullberg
  • Publication number: 20120197030
    Abstract: The current invention relates to the structure, synthesis of dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate, as well as its applications in the palladium catalyzed carbon-chlorine bond activation for Suzuki coupling reactions and carbon-nitrogen bond formation reactions. The dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate could coordinate with the palladium catalyst to activate the inert carbon-chlorine bond highly selectively and catalyze Suzuki coupling reaction with arylboronic acid or carbon-nitrogen bond formation reaction with organic amines. The current invention uses only one step to synthesize dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate is stable in the air. Compared with known synthetic routes of ligands used in activating carbon-chlorine bonds, the method of current invention is short, easy to operate.
    Type: Application
    Filed: December 21, 2009
    Publication date: August 2, 2012
    Applicant: Zhejiang University
    Inventors: Shengming Ma, Bo Lü, Chunling Fu
  • Patent number: 8193384
    Abstract: The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, ?-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: June 5, 2012
    Assignee: Board of Governors for Higher Education, State of Rhode Island and Providence Plantation
    Inventors: Keykavous Parang, Yousef Ahamdibeni
  • Publication number: 20120129969
    Abstract: The invention relates to radiation curable compositions comprising a liquid 0/s(acyl)phosphine photo initiators of formula (Ï): wherein each of Ar1, Ar2 and Ar3 is independently a substituted or unsubstituted aryl group. The invention also relates to stabilized forms of liquid bis(acyl)phosphines of formula (I) and radiation curable composition comprising said stabilized photoinitiators. The radiation curable compositions are selected from the group consisting of an optical fiber coating composition and a coating composition capable of radiation cure on concrete and a coating composition capable of radiation cure on metal.
    Type: Application
    Filed: June 21, 2011
    Publication date: May 24, 2012
    Inventors: Timothy Edward Bishop, Edward Joseph Murphy, John Edmond Southwell, Satyendra Sarmah, TaiYeon Lee
  • Patent number: 8168833
    Abstract: Embodiments of the invention provide a method of using Schwartz Reagent, Cp2Zr(H)Cl, without accumulating or isolating it. Methods provide mixtures of Cp2ZrCl2, reductants that selectively reduce Cp2ZrCl2, and substrates. After reaction of Cp2ZrCl2 and the reductant, an intermediate reduction product is formed, apparently Schwartz Reagent. The in situ Schwartz Reagent then selectively reduces certain functional groups on the substrate. Substrates include tertiary amides, tertiary benzamides, aryl O-carbamates, and heteroaryl N-carbamates, which are reduced to aldehydes, benzaldehydes, aromatic alcohols, and heteroaromatics, respectively. Compared to prior methods, reagents are inexpensive and stable, reaction times are short, and reaction temperature in certain cases is conveniently room temperature. It has been estimated that using the in situ method described herein instead of synthesized or commercially obtained Schwartz Reagent provides a 50% reduction in cost.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: May 1, 2012
    Assignee: Queen's University at Kingston
    Inventors: Yigang Zhao, Victor A. Snieckus
  • Publication number: 20110300482
    Abstract: There is provided a sulfonium salt having high photosensitivity to the i-line. The invention relates to a sulfonium salt represented by formula (1) described below: [in formula (1), R1 to R6 each independently represent an alkyl group, a hydroxy group, an alkoxy group, an alkylcarbonyl group, an arylcarbonyl group, an alkoxycarbonyl group, an aryloxycarbonyl group, an arylthiocarbonyl group, an acyloxy group, an arylthio group, an alkylthio group, an aryl group, a heterocyclic hydrocarbon group, an aryloxy group, an alkylsulfinyl group, an arylsulfinyl group, an alkylsulfonyl group, an arylsulfonyl group, a hydroxy(poly) alkyleneoxy group, an optionally substituted amino group, a cyano group, a nitro group, or a halogen atom, m1 to m6 each represent the number of occurrences of each of R1 to R6, m1, m4, and m6 each represent an integer of 0 to 5, m2, m3, and m5 each represent an integer of 0 to 4, and X? represents a monovalent polyatomic anion].
    Type: Application
    Filed: February 4, 2010
    Publication date: December 8, 2011
    Applicant: SAN-APRO, LTD
    Inventors: Issei Suzuki, Hideki Kimura
  • Publication number: 20110247459
    Abstract: To provide a compound represented by General Formula (1) below, where R denotes a C1-C10 hydrocarbon group, Z denotes any one of a sulfide group, a sulfinyl group and a sulfonyl group, and n denotes an integer of 4 to 8.
    Type: Application
    Filed: March 2, 2011
    Publication date: October 13, 2011
    Inventors: Fumio Hamada, Chun-Bin Li, Yoshihiko Kondo
  • Publication number: 20110215274
    Abstract: Ferroelectric liquid crystal compositions including organic ion pair compounds wherein image sticking is reduced or eliminated. Use of the ferroelectric liquid crystal compositions in a ferroelectric liquid crystal display device allows for rapid image refresh rates without required a DC-balancing algorithm. The organic ion pair compounds provide electrical resistivity values for the compositions that result in reduced image sticking when the compositions are used in FLC display devices.
    Type: Application
    Filed: January 14, 2011
    Publication date: September 8, 2011
    Inventors: Cory Pecinovsky, William Thurmes, Brion C. Koprowski
  • Publication number: 20110190505
    Abstract: This disclosure relates to compounds, reagents, and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. For example, this disclosure provides universal “locked” aryl substituents that result in StereoElectronic Control of Unidirectional Reductive Elimination (SECURE) from diaryliodonium salts. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.
    Type: Application
    Filed: February 4, 2011
    Publication date: August 4, 2011
    Inventor: Stephen DiMagno
  • Publication number: 20110152523
    Abstract: The present invention provides a process for efficiently producing an alkylated aromatic compound in good yield, by a cross-coupling reaction between an alkyl halide and an aromatic magnesium reagent. A process for producing an aromatic compound represented by Formula (1): R—Ar???(1) wherein R is a hydrocarbon group, and Ar? is an aryl group; the process comprising: reacting a compound represented by Formula (2): R—X??(2) wherein X is a halogen atom, and R is as defined above, with a magnesium reagent represented by Formula (3): Ar?—MgY??(3) wherein Y is a halogen atom, and Ar? is as defined above, in the presence of a catalyst for cross-coupling reactions comprising an iron compound and a bisphosphine compound represented by Formula (4): wherein Q is a divalent group derived from an aromatic ring by removing two hydrogen (H) atoms on adjacent carbon atoms; and each Ar is independently an aryl group.
    Type: Application
    Filed: March 10, 2009
    Publication date: June 23, 2011
    Applicant: Kyoto University
    Inventors: Masaharu Nakamura, Takuji Hatakeyama, Yu-ichi Fujiwara
  • Patent number: 7943775
    Abstract: A tissue is imaged to detect the presence of amyloid deposits or other target proteins prior to their aggregation into plaques, with the assistance of the administration of a labeled bifunctional compound of which one functionality binds to the target protein and the second functionality binds to a chaperone protein that is present in the tissue of interest. The two functionalities have different binding affinities, the target-binding functionality having the greater binding affinity, with the result that the bifunctional compound preferentially remains in the tissue when bound to the chaperone and then the target protein while bifunctional compound that is not bound to the target protein will leave the tissue.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: May 17, 2011
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: King C. Li, S. Narasimhan Danthi
  • Publication number: 20110098485
    Abstract: Compounds of the formula I, in the form of mixtures comprising predominantly one enantiomer or in the form of pure enantiomers, secondary phosphine-Q-P*(?O)HR1 (I) in which secondary phosphine is a C-bonded, secondary phosphine group —P(R)2; in which R is in each case independently hydrocarbon radicals or heterohydrocarbon radicals; Q is a bivalent, achiral, aromatic base skeleton, a bivalent, achiral ferrocene base skeleton, an optionally substituted bivalent cycloalkane or heterocycloalkane skeleton, or a C1-C4-alkylene skeleton, and in which base skeletons a secondary phosphine group is bonded directly to a carbon atom, or, in the case of cyclic base skeletons, directly to a carbon atom or via a C1-C4-alkylene group, and in which base skeletons a P-chiral group —P*(O)HR1 is bonded to a carbon atom such that the phosphorus atoms are linked via 1 to 7 atoms of a carbon chain optionally interrupted by heteroatoms from the group of O, S, N, Fe or Si; P* is a chiral phosphorus atom; and R1 is a hydrocarbon radi
    Type: Application
    Filed: November 14, 2008
    Publication date: April 28, 2011
    Inventors: Benoît Pugin, Heidi Landert, Björn Gschwend, Andreas Pfaltz, Felix Spindler
  • Patent number: 7932239
    Abstract: Methods and compositions involving a class of boron-protected phenylphosphine agents having increased cell permeability and having improved chemical stability for treating or for preventing neuronal cell death-related diseases or conditions in a human or a non-human animal.
    Type: Grant
    Filed: April 27, 2006
    Date of Patent: April 26, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald T. Raines, Leonard A. Levin
  • Publication number: 20110087013
    Abstract: The present invention concerns a synthesis process comprising the following steps (i) reacting 3-ethyl-4-nitrobenzoic acid with thionyl chloride to produce a 3-ethyl-4-nitrobenzoic acid chloride or a 3-ethyl-4-nitrobenzoic acid anhydride from 3-ethyl-4-nitrobenzoic acid by means of water cleavage and (ii) Friedel-Crafts acylation by reacting the 3-ethyl-4-nitrobenzoic acid chloride or the 3-ethyl-4-nitrobenzoic acid anhydride with an optionally substituted aryl-H to form an optionally substituted (3-ethyl-4-nitrophenyl)-aryl-methanone. In addition the present invention concerns compounds containing (3-ethyl-4-nitrophenyl)-aryl-methanone, characterized in that the optionally substituted aryl is an optionally substituted condensed aromate.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 14, 2011
    Inventor: Bernhard Knipp
  • Patent number: 7915455
    Abstract: The invention provides a transition metal complex of formula (3) below: wherein R1, R2, R3, R4, R5, R6, R7 and R8 are the same or different and each independently represents a hydrogen atom, a halogen atom or a substituted or unsubstituted alkyl group having 1 to 10 carbon atom(s); R5 represents a hydrogen atom, a fluorine atom or a substituted or unsubstituted alkyl group having 1 to 10 carbon atom(s); X1 represents a hydrogen atom, a halogen atom or a substituted or unsubstituted alkyl group having 1 to 10 carbon atom(s); L represents a balancing counter ion or neutral ligand similar to X1 that is bonding or coordinating to metal M; and q represents an integer of 0 or 1, and G20 represents any one of G21 to G26 below: where A1 represents an element of Group 15 of the periodic table, wherein A1 in G23 represents an anion of an element of Group 15 of the periodic table, and A1 in G21 represents a nitrogen atom; R9, R14, R12, R13, R19, R20, R10, R11, R15, R16, R17, R18, R19, R20, R21 and R22 ea
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: March 29, 2011
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yuka Otomaru, Hidenori Hanaoka
  • Patent number: 7901812
    Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N?(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: March 8, 2011
    Assignees: ACEP Inc., Centre National de la Recherche Scientifique, Universite de Montreal
    Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
  • Publication number: 20110054205
    Abstract: A compound comprising a sulfonated triorganophosphine of formula R1R2PR3[SO3M)]n, wherein R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups; wherein R3 represents a branched divalent or polyvalent, alkylene or alicyclic radical that is bonded to the phosphorus atom and to one or more sulfonate substituents, and further wherein R3 does not contain any aryl moieties; M represents a monovalent cation; and n is an integer representing a total number of sulfonated substituents. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products. The ligand is incapable of alkyl-aryl exchange, thereby leading to reduced ligand usage and improving ligand and transition metal, e.g., rhodium, recovery and recycling, as compared with prior art ligands.
    Type: Application
    Filed: January 9, 2009
    Publication date: March 3, 2011
    Applicant: Dow Global Technologies Inc.
    Inventors: Michael L. Tulchinsky, Anthony G. Abatjoglou
  • Publication number: 20110054203
    Abstract: A compound comprising a sulfonated dihydrocarbyl(arylalkyl)phosphine of formula R1R2PR3—(SO3M)n, wherein the R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups, and R3 is a divalent or polyvalent arylalkylene radical such that the alkyl moiety is bonded to the phosphorus atom and the aryl moiety is bonded to the alkyl and is also substituted with one or more sulfonate groups; M is a monovalent cation, and n ranges from 1 to 3. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products. The ligand is incapable of alkyl-aryl exchange, thereby leading to reduced ligand usage and improved ligand and transition metal, e.g., rhodium, recovery and recycling.
    Type: Application
    Filed: January 9, 2009
    Publication date: March 3, 2011
    Applicant: DOW GLOBAL TECHNOLOGIES INC.
    Inventors: Michael L. Tulchinsky, Ronald R. Peterson
  • Publication number: 20110054204
    Abstract: A compound comprising a class of sulfonated triorganophosphine compounds of formula R1R2P—R3[—O—(CH2)n—(SO3M)]m, wherein the R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups, wherein R3 represents a divalent or polyvalent alkylene or alicyclic radical that is bonded to the phosphorus atom and to one or more sulfonate substituents via an alkylether link, and further wherein R3 does not contain any aryl moieties; n is an integer reflecting a number of methylene groups in the alkylether link; M represents a monovalent cation; and m is an integer representing a total number of sulfonated alkylether substituents. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products.
    Type: Application
    Filed: January 9, 2009
    Publication date: March 3, 2011
    Applicant: Dow Global Technologies Inc.
    Inventors: Michael L. Tulchinsky, Robert E. Hefner, JR.
  • Patent number: 7897820
    Abstract: A process for preparing Erianin (Dihydro Combretastation A-4), wherein 3,4,5-trimethoxy benzaldehyde is converted to phosphonium salt or phosphonate ester or the likes thereof, then reacted with isovanillin (3-hydroxyl-4-methoxyl benzaldehyde) including a protected hydroxyl in the 3-position, followed by hydrogenation and deprotection.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: March 1, 2011
    Assignee: Zhe Jiang Cell Biomedical Research Co., Ltd.
    Inventors: Yiping Li, Shuangxi Liu
  • Publication number: 20110028718
    Abstract: A substituted paracyclophane is described of formula (I) wherein X1 and X2 are linking groups comprising between 2 to 4 carbon atoms, Y1 and Y2 are selected from the group consisting of hydrogen, halide, oxygen, nitrogen, alkyl, cycloalkyl, aryl or heteroaryl and Z is a substituted or unsubstituted alkyl group, aryl group or heteroaryl group. Preferably X1 and X2 are —(C2H4)— and Z is a substituted aryl group. The substituted paracyclophane provides transition metal catalysts that are useful in C—C and C—N bond formation and asymmetric hydrogenation reactions.
    Type: Application
    Filed: August 21, 2008
    Publication date: February 3, 2011
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Jianliang Xiao, Jiwu Ruan
  • Patent number: 7858784
    Abstract: Ligands for transition metals are disclosed herein, which may be used in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The disclosed methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition-metal-catalyzed cross-coupling reactions.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: December 28, 2010
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Brett P. Fors, David S. Surry
  • Patent number: 7838665
    Abstract: The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: November 23, 2010
    Assignee: The Regents of the University of California
    Inventors: Eliana Saxon, Carolyn Ruth Bertozzi
  • Patent number: 7799293
    Abstract: Methods of separating actinides from lanthanides are disclosed. A regio-specific/stereo-specific dithiophosphinic acid having organic moieties is provided in an organic solvent that is then contacted with an acidic medium containing an actinide and a lanthanide. The method can extend to separating actinides from one another. Actinides are extracted as a complex with the dithiophosphinic acid. Separation compositions include an aqueous phase, an organic phase, dithiophosphinic acid, and at least one actinide. The compositions may include additional actinides and/or lanthanides. A method of producing a dithiophosphinic acid comprising at least two organic moieties selected from aromatics and alkyls, each moiety having at least one functional group is also disclosed. A source of sulfur is reacted with a halophosphine. An ammonium salt of the dithiophosphinic acid product is precipitated out of the reaction mixture. The precipitated salt is dissolved in ether.
    Type: Grant
    Filed: September 11, 2006
    Date of Patent: September 21, 2010
    Assignee: Battelle Energy Alliance, LLC
    Inventors: Dean R. Peterman, John R. Klaehn, Mason K. Harrup, Richard D. Tillotson, Jack D. Law
  • Publication number: 20100233444
    Abstract: A composition comprising a polymer which contains hydroxyl groups, the composition being suitable as a coating for an IR-imagable lithographic precursor, the composition comprising one or more agent(s) which: a) absorbs IR radiation of wavelength greater than 800 nm and consequently generates heat; b) functions as an insolubiliser which inhibits dissolution of non-imaged regions of the coating in a developer but permits dissolution of imaged regions during development; and c) improves the inhibition to dissolution of the non-imaged regions and/or the dissolution of the imaged regions so as to improve the dissolution contrast ratio (DCR) of the non-imaged/imaged regions; wherein the agent which performs function c) comprises a moiety which has hydrophobic and ionic character. Such a composition can show excellent selectivity as regards dissolution rates in developer, as between the imaged and non-imaged areas, whilst the energy needed to achieve this differentiation (or “operating speed”) is not comprised.
    Type: Application
    Filed: July 2, 2007
    Publication date: September 16, 2010
    Inventors: Peter Andrew Reath Bennett, Roberto Massimo Allegrini
  • Patent number: 7754924
    Abstract: A method of preparing an aromatic phosphine monosulfonate in zwitterionic form, such as dicyclohexylphenylphosphine monosulfonate zwitterion, involving contacting an aromatic phosphine with a sulfonating agent to provide a reaction mixture containing aromatic phosphine monosulfonate in acid form and unconverted sulfonating agent; quenching or removing substantially all of the unconverted sulfonating agent; partially neutralizing the aromatic phosphine monosulfonate in acid form to phase separate aromatic phosphine monosulfonate in zwitterionic form as a solid or neat liquid layer; and collecting the zwitterion as a solid or neat liquid. The zwitterion may be neutralized to form the corresponding aromatic phosphine monosulfonate metal salt, which is useful in preparing catalysts for hydroformylation processes.
    Type: Grant
    Filed: September 14, 2006
    Date of Patent: July 13, 2010
    Assignee: Dow Global Technologies Inc.
    Inventors: Donald L. Morrison, Kurt D. Olson, Walter C. Reed, Anthony G. Abatjoglou
  • Publication number: 20100168456
    Abstract: The present invention provides P-chiral compounds of general formulae (II) and (III): in formula (II) at least one of R21, R25, R26 and R30 is independently selected from CM alkyl, CF3, C1-4 alkoxy, phenyl and benzyloxy and the remaining substituents selected from R21, R25, R26 and R30 are hydrogen; at least one of R22, R24, R27 and R29 are independently selected from C1-14 alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy and the remaining substituents selected, from R22, R24, R27 and R29 are hydrogen; and R23 and R28 are independently selected from hydrogen, CM alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy; in formula (III) at least one of R21, R25, R26 and R30 is independently selected from phenyl and benzyloxy and the remaining substituents selected from R21, R25, R—26 and R30 are hydrogen; and R22, R—23 R24, R27, R28 and R29 are independently selected from hydrogen, C1-14 alkyl, CF3, C1-14 alkoxy, phenyl and benzyloxy.
    Type: Application
    Filed: March 28, 2008
    Publication date: July 1, 2010
    Applicant: Celtic Catalysts Limited
    Inventors: Declan Gilheany, Graham R. Cumming, Gary King, Matthias Voegler, Vladimir Larichev
  • Publication number: 20100145060
    Abstract: Embodiments of the invention provide a method of using Schwartz Reagent, Cp2Zr(H)Cl, without accumulating or isolating it. Methods provide mixtures of Cp2ZrCl2, reductants that selectively reduce Cp2ZrCl2, and substrates. After reaction of Cp2ZrCl2 and the reductant, an intermediate reduction product is formed, apparently Schwartz Reagent. The in situ Schwartz Reagent then selectively reduces certain functional groups on the substrate. Substrates include tertiary amides, tertiary benzamides, aryl O-carbamates, and heteroaryl N-carbamates, which are reduced to aldehydes, benzaldehydes, aromatic alcohols, and heteroaromatics, respectively. Compared to prior methods, reagents are inexpensive and stable, reaction times are short, and reaction temperature in certain cases is conveniently room temperature. It has been estimated that using the in situ method described herein instead of synthesized or commercially obtained Schwartz Reagent provides a 50% reduction in cost.
    Type: Application
    Filed: December 3, 2009
    Publication date: June 10, 2010
    Inventors: Yigang Zhao, Victor A. Snieckus
  • Patent number: 7732546
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerizable hydrophilic siloxanyl monomers.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 8, 2010
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Publication number: 20100126842
    Abstract: The present invention relates to the field of processing hydrocarbons which causes corrosion in the metal surfaces of processing units. The invention addresses the technical problem of high temperature naphthenic acid corrosion and sulphur corrosion and provides a solution to inhibit these types of corrosion. The composition formed by reacting high reactive polyisobutylene (HRPIB) with phosphorous pentasulphide in presence of catalytic amount of sulphur provides high corrosion inhibition efficiency in case of high temperature naphthenic acid corrosion inhibition and sulphur corrosion inhibition. The invention is useful in all hydrocarbon processing units, such as, refineries, distillation columns and other petrochemical industries.
    Type: Application
    Filed: March 27, 2008
    Publication date: May 27, 2010
    Applicant: Dorf Ketal Chemicals (I) Private Limited
    Inventor: Mahesh Subramaniyam
  • Publication number: 20100113255
    Abstract: Novel bidentate ligands of general formula (I) are described Formula (I): R represents a hydrocarbyl aromatic structure. The substituent(s) Yx on the aromatic structure has a total X=1-n ?tYX of atoms other than hydrogen such that X-1-n?tYX is 4 where n is the total number of substituent(s) YX and tYX represents the total number of atoms other than hydrogen on a particular substituent YX. The groups X1, X2, X3 and X4 are joined to Q1 or Q2 via tertiary carbon atoms to the respective atom Q1 or Q2; and Q1 and Q2 each independently represent phosphorus, arsenic or antimony. A catalyst system and a process for the carbonylation of ethylenically unsaturated compounds utilising the catalyst system is also described.
    Type: Application
    Filed: November 27, 2007
    Publication date: May 6, 2010
    Applicant: LUCITE INTERNATIONAL UK LIMITED
    Inventors: Graham Ronald Eastham, Ian Butler
  • Patent number: 7709548
    Abstract: A monosulfonium salt in which very little unreacted raw material remains, which has a purity of at least 96%, and which has one sulfonio group in its molecule is manufactured without a refining step. After (a) an aryl compound, (b) a sulfoxide compound, (c) a dehydrating agent, and (d) a BF4, PF6, AsF6, or SbF6 salt of an alkali metal or an alkaline earth metal are introduced into a reaction system, (e) an inorganic acid is added, so that the aryl compound (a) and the sulfoxide compound (b) are subjected to dehydration condensation.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: May 4, 2010
    Assignee: San-Apro Limited
    Inventors: Masashi Date, Hideki Kimura, Shinji Yamashita, Jiro Yamamoto