Processes Patents (Class 568/426)
  • Patent number: 4297520
    Abstract: p-Methoxytoluene is oxidized with a dichromate ion forming substance and sulfuric acid to give anisaldehyde in good yields. The oxidation proceeds with improved efficiency in the presence of a manganese compound.
    Type: Grant
    Filed: March 4, 1980
    Date of Patent: October 27, 1981
    Assignee: Daiwa Chemical Company Ltd.
    Inventor: Kozo Nakaoji
  • Patent number: 4288364
    Abstract: When 3-(2-hydroxyiminoacetylamino)-2-oxo-azetidine compounds are treated with reactive derivatives of carbonic acid half-esters in aqueous media in the presence of bases a fragmentation takes place which, in addition to 3-amino-2-oxo-azetidines, also yields nitriles which, compared with the 2-hydroxyiminoacetyl group, have one less carbon atom. The resulting products are intermediates for the preparation of nocardicin-like antibiotics.The deacylation procedure of this specification offers advantages over the multi-stage deacylation procedure known hitherto, inasmuch as higher yields of 3-amino-2-oxoazetidine compounds are obtained and the acyl group can be obtained in the form of a nitrile which is shorter by one carbon atom.
    Type: Grant
    Filed: May 15, 1979
    Date of Patent: September 8, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl Schaffner, Hansuli Wehrli, Beat Muller, Riccardo Scartazzini
  • Patent number: 4282251
    Abstract: Cinnamylalkyl-1-naphthylmethylamines, useful as antimycotic agents, and processes for their production.
    Type: Grant
    Filed: December 3, 1979
    Date of Patent: August 4, 1981
    Assignee: Sandoz Ltd.
    Inventor: Daniel Berney
  • Patent number: 4280011
    Abstract: The use of acetals as aldehyde generators in foodstuff applications is disclosed.
    Type: Grant
    Filed: April 5, 1978
    Date of Patent: July 21, 1981
    Assignee: Hercules Incorporated
    Inventor: Robert S. DeSimone
  • Patent number: 4275241
    Abstract: A process for the preparation of a-phenoxy-benzaldehyde which comprises contacting the 3-phenoxy-benzyl alcohol of the formula ##STR1## wherein R.sup.1 and R.sup.2 are identical or different and represent hydrogen or halogen with an aqueous solution of a dichromate in the presence of aqueous sulphuric acid at a temperature in the range of 50.degree. to 125.degree. C. The 3-phenoxy-benzaldehyde can be in a mixture of other organic compounds such as obtained by hydrolyzing a 3-phenoxy toluene chlorinated in the side chain at a temperature of 140.degree.-210.degree. C. under pressure.
    Type: Grant
    Filed: October 29, 1979
    Date of Patent: June 23, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegfried Bohm, Alfons Klein, Karlfried Wedemeyer
  • Patent number: 4273940
    Abstract: It has been found that bis(2-benzylaminoethyl)-disulfides with the phenyl rings carrying various simple substituents, are highly effective anti-inflammatories and inhibit chemotaxis of human neutrophils.
    Type: Grant
    Filed: May 13, 1980
    Date of Patent: June 16, 1981
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, George W. Carter
  • Patent number: 4271320
    Abstract: An industrially suitable process for producing a higher carbonyl compound by the oxidation of an olefinic compound having at least six carbon atoms is provided. Said improved process comprises oxidizing the olefinic compound in aqueous medium containing palladium or salt thereof and a copper salt in the presence of a specific water-soluble polyoxyalkylene compound in an amount of from about 1/4 to about 3 parts by weight per 1 part by weight of water contained in the reaction mixture. The improvement is demonstrated in terms of yield, selectivity, separation of the product, and recycle of the catalyst.
    Type: Grant
    Filed: August 31, 1979
    Date of Patent: June 2, 1981
    Assignee: Kuraray Co., Ltd.
    Inventors: Yasuo Tokitoh, Noriaki Yoshimura, Masuhiko Tamura
  • Patent number: 4209644
    Abstract: An unsaturated carbonyl compound, for example, one expressed by the following formula, ##STR1## is prepared by maintaining at an elevated temperature a novel allyl acetal of a .beta.,.gamma.-unsaturated aldehyde, for example, one expressed by the following formula ##STR2## The allyl acetal can be derived, for example, for 3-methyl-3-butenal-1 having 5 carbon atoms and prenyl alcohol having 5 carbon atoms. Thus, the unsaturated aldehyde having the increased number of carbon atoms can be formed in a high yield by a relatively simple reaction.
    Type: Grant
    Filed: November 30, 1977
    Date of Patent: June 24, 1980
    Assignee: Teijin Limited
    Inventors: Yataro Ichikawa, Teizo Yamaji, Mamoru Yamamoto
  • Patent number: 4206139
    Abstract: Novel benzaldehydes of the formula: ##STR1## Where n.sup.1 is the integer 1-8 and each OR.sup.1 group is hydroxy or a protective group which can be converted or removed to provide the dihydroxyphenyl moiety.The benzaldehydes are particularly useful as intermediates in the preparation of yellow azomethine dye developers.
    Type: Grant
    Filed: September 27, 1978
    Date of Patent: June 3, 1980
    Assignee: Polaroid Corporation
    Inventors: Elbert M. Idelson, Charles E. Jandrue
  • Patent number: 4205188
    Abstract: A process is provided for the production of hydroxybenzyl alcohols, comprising condensing phenol with formaldehyde in an alkaline solution to form a mixture of ortho- and para-hydroxymethyl phenols, and solvent extracting unreacted phenol from the resulting alkaline hydroxybenzyl alcohol condensate solution. The phenol-reduced hydroxybenzyl alcohol condensate solution is particularly suited for treatment with excess caustic and subsequent oxidation of the resulting aqueous solution of ortho- and para-hydroxybenzyl alcohols-sodium salt to yield the corresponding ortho- and para-hydroxybenzaldehydes-sodium salt.
    Type: Grant
    Filed: September 8, 1978
    Date of Patent: May 27, 1980
    Assignee: The Dow Chemical Company
    Inventors: Wayne C. Muench, Thad S. Hormel, Pamela M. Kirchhoff, Lanny A. Robbins