Aldehydes Patents (Class 568/420)
  • Patent number: 9295971
    Abstract: The present invention relates to an apparatus of the loop Venturi reactor type for the continuous reaction of liquids with gases, in particular for hydrogenations, oxidations or acetylations, e.g. for the preparation of toluenediamine by hydrogenation of dinitrotoluene, and a process for the continuous reaction of liquid reactants with gaseous reactants in the apparatus. Here, the cooling medium surrounds the tubes of the heat exchanger of the apparatus of the invention whereas the reaction takes place in the tubes.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: March 29, 2016
    Assignee: BASF SE
    Inventors: Oliver Bey, Andreas Raichle, Hartmut Riechers, Roland Mueller, Wolfgang Mackenroth, Peter Zehner
  • Patent number: 9109186
    Abstract: Compounds of formula (I) wherein R is methyl or ethyl, having floral, green odor notes, their use as fragrance and perfumed products comprising them.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: August 18, 2015
    Assignee: Givaudan S.A.
    Inventors: Marius Geiger, Martin Lovchik
  • Patent number: 9051531
    Abstract: The invention relates to a compound of general formula I represented below: wherein: R1, R2 and R3 each independently represent a hydrogen atom or saturated or unsaturated, branched or non-branched C1 to C5 alkyl group; m is an integer between 1 and 4; n is an integer between 2 and 4; characterized in that the ring is saturated and comprises from 5 to 8 carbons, that the total number of carbons of the ring and of the radicals R1, R2 and R3 is between 7 and 11 and it being understood that said compound of formula (I) is not: 6-cycloheptylidenehexanal 4-(4-methylcyclohexylidene)-butanal 4-(4-tert-butylcyclohexylidene)-butanal 4-(3,3,5-trimethylcyclohexylidene)-butanal as well as a method of synthesizing said compounds, and their uses in perfumery.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: June 9, 2015
    Assignee: V.MANE FILS
    Inventors: Agnès Muratore, Caroline Plessis, Jean-Jacques Chanot
  • Patent number: 8993819
    Abstract: The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closing metathesis of unsymmetric 1,8-dienes whose C—C double bond at the 8 position is nonterminal. Cycloheptene and the cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride conversion products thereof, and the derivatives thereof, are important synthesis units for active ingredient compounds. The ring-closing metathesis is preferably performed as a reactive distillation. The unsymmetric 1,8-dienes for the ring-closing metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation from the corresponding unsaturated carboxylic acids or carboxylic acid derivatives.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: March 31, 2015
    Assignee: BASF SE
    Inventors: Joaquim Henrique Teles, Michael Limbach, Richard Dehn, Stephan Deuerlein, Manuel Danz
  • Publication number: 20150073164
    Abstract: The present invention provides a method for adsorbing carbon dioxide onto porous metal-organic framework materials, a method for cooling porous metal-organic framework materials, a method for obtaining aldehyde using porous metal-organic framework materials and a method for warming porous metal-organic framework materials. In each method, porous metal-organic framework materials are used while an electric field or an electromagnetic field is applied to the porous metal-organic framework materials, or while a magnetic field or an electromagnetic field is applied to the porous metal-organic framework materials. If an electric field is applied, at least one organic compound included in the porous metal-organic framework materials is a polar compound. Instead, if a magnetic field is applied, at least one metal included in the porous metal-organic framework materials has an unpaired electron.
    Type: Application
    Filed: September 4, 2014
    Publication date: March 12, 2015
    Inventors: TAKAIKI NOMURA, TAKASHI KOUZAKI, TAKAHIRO KURABUCHI, KAZUHITO HATO
  • Publication number: 20150051133
    Abstract: An aldehyde of formula (I) in the form of any one of its stereoisomers or a mixture thereof, wherein each dotted line, independently from each other, represents a single or double bond; n is 0 or 1; R1 is a hydrogen atom or a methyl group; R2 is a hydrogen atom or a methyl or ethyl group; and R3, which can be present in any of positions 2 to 6 of the cyclic moiety, is a hydrogen atom or a methyl or ethyl group, or a CH2 group bridging positions 3 and 6. Also, the use of the aldehyde as perfuming ingredient to impart odor notes of the aldehyde, lily of the valley type.
    Type: Application
    Filed: January 24, 2013
    Publication date: February 19, 2015
    Applicant: FIRMENICH SA
    Inventor: Robert Moretti
  • Publication number: 20140343326
    Abstract: An improved process for oxidation of at least one alcohol group of at least one chemical compound to the corresponding carbonyl group. Said process is carried out in the presence of a buffered oxidative hypohalous solution and of a nitroxide oxidation catalyst. It is characteristically carried out within a micro-reactor; the buffered oxidative hypohalous solution being extemporaneously prepared at a buffered pH comprised between 7 and less than 8.5 (7?pH<8.5).
    Type: Application
    Filed: January 17, 2013
    Publication date: November 20, 2014
    Inventors: Olivier Gaurat, Clemens Rudolf Horn, Patrick Jean
  • Publication number: 20140242867
    Abstract: Lignin compositions, products produced from them or containing them, methods to produce them, spinning methods, methods to convert lignin to a conversion product and conversion products produced by the methods are described.
    Type: Application
    Filed: April 4, 2012
    Publication date: August 28, 2014
    Inventors: Robert Jansen, Aharon Eyal, Noa Lapidot, Bassem Hallac, Ziv-Vladimir Belman, Shmuel Kenig
  • Publication number: 20140221503
    Abstract: The invention relates to a compound of general formula I represented below: wherein: R1, R2 and R3 each independently represent a hydrogen atom or saturated or unsaturated, branched or non-branched C1 to C5 alkyl group; m is an integer between 1 and 4; n is an integer between 2 and 4; characterised in that the ring is saturated and comprises from 5 to 8 carbons, that the total number of carbons of the ring and of the radicals R1, R2 and R3 is between 7 and 11 and it being understood that said compound of formula (I) is not: 6-cycloheptylidenehexanal 4-(4-methylcyclohexylidene)-butanal 4-(4-tert-butylcyclohexylidene)-butanal 4-(3,3,5-trimethylcyclohexylidene)-butanal as well as a method of synthesising said compounds, and their uses in perfumery.
    Type: Application
    Filed: October 9, 2012
    Publication date: August 7, 2014
    Applicant: V. Mane Fils
    Inventors: Agnès Muratore, Caroline Plessis, Jean-Jacques Chanot
  • Publication number: 20140221263
    Abstract: Compounds of formula (I) wherein R is methyl or ethyl, having floral, green odor notes, their use as fragrance and perfumed products comprising them.
    Type: Application
    Filed: September 6, 2012
    Publication date: August 7, 2014
    Applicant: GIVAUDAN SA
    Inventors: Marius Geiger, Martin Lovchik
  • Patent number: 8754263
    Abstract: Disclosed are methods for generating propylene glycol, ethylene glycol and other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols from biomass using hydrogen produced from the biomass. The methods involve reacting a portion of an aqueous stream of a biomass feedstock solution over a catalyst under aqueous phase reforming conditions to produce hydrogen, and then reacting the hydrogen and the aqueous feedstock solution over a catalyst to produce propylene glycol, ethylene glycol and the other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols. The disclosed methods can be run at lower temperatures and pressures, and allows for the production of oxygenated hydrocarbons without the need for hydrogen from an external source.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: June 17, 2014
    Assignee: Virent, Inc.
    Inventor: Randy D. Cortright
  • Patent number: 8742176
    Abstract: The invention relates to a method of producing optically active 4-chloro-3-hydroxybutanal compound (2) by reacting chloroacetaldehyde with aldehyde compound (1) in the presence of optically active pyrrolidine compound (5). wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: June 3, 2014
    Assignee: Sumitomo Chemical Company, Limited
    Inventor: Yujiro Hayashi
  • Patent number: 8692024
    Abstract: The invention provides method of producing n-butyraldehyde using recombinant solventogenic bacteria and recombinant microorganisms.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: April 8, 2014
    Assignee: Eastman Renewable Materials, LLC
    Inventors: Jay Kouba, Mounir Izallalen, Jill Bradshaw
  • Publication number: 20140087988
    Abstract: The invention concerns the use of 6-cyclopentylidenehexane derivatives—6, cyclopentylidenehexan-1-ol and 6-cyclopentylidenehexanal—as sensory agents giving off a fragrance and/or a flavor of interest for a use in perfumery, in cosmetic, in parapharmacy, in detergent industry and in the food industry.
    Type: Application
    Filed: May 16, 2012
    Publication date: March 27, 2014
    Inventors: Agnès Muratore, Jean-Jacques Chanot
  • Patent number: 8624057
    Abstract: There is provided an isoprenoid according to the general formula (I) wherein R1 and R2 are independently selected from H and alkyl; and R3, R4, R5 and R6 are independently selected from groups of the general formula (II) and (III) wherein R7 and R8 each represent a group of general formula CO—R9, in which each R9 is independently selected from H, OH, alkyl and alkoxy groups, or R7 and/or R8 present in R3 and R4 and/or in R5 and R6 combine to form a group of the general formula (IV) wherein R10 is selected from OH and alkoxy; or salts thereof. The isoprenoids are of particular use in the preparation of liposomes, for use in the delivery of pharmaceutically active components to a subject human or animal.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: January 7, 2014
    Assignee: University of Plymouth
    Inventor: Steven John Rowland
  • Publication number: 20130331611
    Abstract: The present invention relates to the field of catalytic hydrogenation and, more particularly, to a process for the reduction by hydrogenation, using molecular H2, of a C6-C20 conjugated dienal into the corresponding deconjugated enal, characterized in that said process is carried out in the presence of a catalytic system comprising at least a base and at least one complex in the form of a rhodium complex comprising a C34-C60 bidentate diphosphine ligand (L2) coordinating the rhodium.
    Type: Application
    Filed: February 17, 2012
    Publication date: December 12, 2013
    Applicant: FIRMENICH SA
    Inventors: Michel Alfred Joseph SAUDAN, Sylvia Joyeuse Adélaïde Ada SAUDAN
  • Patent number: 8604225
    Abstract: The present invention relates to a method of producing 5-hydroxymethylfurfural by dehydration of fructose and/or glucose and/or mannose.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: December 10, 2013
    Assignee: Novozymes, A/S
    Inventors: Sven Pedersen, Troels B. Christensen, Astrid Boisen, Vibeke W. Jurgensen, Thomas S. Hansen, Soeren Kegnaes, Anders Riisager, John M. Woodley, Jacob S. Jensen, Wenjing Fu
  • Patent number: 8592633
    Abstract: Methods and systems for electrochemical conversion of carbon dioxide to carboxylic acids, glycols, and carboxylates are disclosed. A method may include, but is not limited to, steps (A) to (D). Step (A) may introduce water to a first compartment of an electrochemical cell. The first compartment may include an anode. Step (B) may introduce carbon dioxide to a second compartment of the electrochemical cell. The second compartment may include a solution of an electrolyte and a cathode. Step (C) may apply an electrical potential between the anode and the cathode in the electrochemical cell sufficient to reduce the carbon dioxide to a carboxylic acid intermediate. Step (D) may contact the carboxylic acid intermediate with hydrogen to produce a reaction product.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: November 26, 2013
    Assignee: Liquid Light, Inc.
    Inventors: Emily Barton Cole, Kyle Teamey, Andrew B. Bocarsly, Narayanappa Sivasankar
  • Patent number: 8557262
    Abstract: The present invention provides divinyl ether derivatives capable of releasing in a controlled manner at least one active aldehyde and/or ketone into the surrounding environment. The invention relates to the use of these divinyl ether derivatives as perfuming or flavoring ingredients, as well as to the perfuming compositions and consumer articles containing them.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: October 15, 2013
    Assignee: Firmenich SA
    Inventors: Gary Bernard Womack, Robert Langley Fuller, Glenn Paul Johannes Verhovnik, Nathalie Pinel, Magali Lateulere, Marie Buy
  • Publication number: 20130232852
    Abstract: The present invention is directed generally to a method of production of value-added, biobased chemicals from lignin sources, including waste lignin. A method of using a depolymerization of lignin to create a tiered production of biobased aromatic chemicals and biofuels is also described herein. The method described herein may also allow for the selective production of the biobased aromatic chemicals and biofuels. Additionally, a reduction of waste products may also be provided from the present method.
    Type: Application
    Filed: April 23, 2012
    Publication date: September 12, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Vladimir Romakh, Benjamin M.T. Scott
  • Publication number: 20130225849
    Abstract: The present invention relates to a method of purifying organic diphosphite compounds.
    Type: Application
    Filed: December 31, 2012
    Publication date: August 29, 2013
    Applicant: BASF SE
    Inventor: BASF SE
  • Publication number: 20130197178
    Abstract: The present invention provides novel and stable crystalline 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes. The present invention also provides methods of making 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes. The present invention also provides methods of using 1H-1,2,3 triazolium carbenes and metal complexes of 1H-1,2,3 triazolium carbenes in catalytic reactions.
    Type: Application
    Filed: April 26, 2011
    Publication date: August 1, 2013
    Applicant: The Regents of the University of California
    Inventors: Guy Bertrand, Gregorio Gulsado-Barrios, Jean Bouffard, Bruno Donnadieu
  • Patent number: 8492595
    Abstract: Disclosed are methods for generating propylene glycol, ethylene glycol and other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols from biomass using hydrogen produced from the biomass. The methods involve reacting a portion of an aqueous stream of a biomass feedstock solution over a catalyst under aqueous phase reforming conditions to produce hydrogen, and then reacting the hydrogen and the aqueous feedstock solution over a catalyst to produce propylene glycol, ethylene glycol and the other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols. The disclosed methods can be run at lower temperatures and pressures, and allows for the production of oxygenated hydrocarbons without the need for hydrogen from an external source.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: July 23, 2013
    Assignee: Virent, Inc.
    Inventor: Randy D. Cortright
  • Patent number: 8481728
    Abstract: A process of making entecavir comprising converting a compound of formula (M5) to entecavir, wherein the two PGs on the formula (M5) are taken together to form an optionally substituted six- or seven-member cyclic ring.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: July 9, 2013
    Assignee: Scinopharm Taiwan, Ltd.
    Inventors: Tsung-Cheng Hu, Hung-Tsung Huang
  • Publication number: 20130157923
    Abstract: A novel odorant of formula (I) wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are independently selected from H, CH3, and C2H5; X is selected from —CH2OH, —CH2OCOCH3 and —CHO and —CHO, n is selected from 0 and 1. The dotted line represents double bond or single bond.
    Type: Application
    Filed: August 18, 2011
    Publication date: June 20, 2013
    Inventor: Kedar Ramesh Vaze
  • Patent number: 8466306
    Abstract: A compound comprising a sulfonated dihydrocarbyl(arylalkyl)phosphine of formula R1R2PR3—(SO3M)n, wherein the R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups, and R3 is a divalent or polyvalent arylalkylene radical such that the alkyl moiety is bonded to the phosphorus atom and the aryl moiety is bonded to the alkyl and is also substituted with one or more sulfonate groups; M is a monovalent cation, and n ranges from 1 to 3. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products. The ligand is incapable of alkyl-aryl exchange, thereby leading to reduced ligand usage and improved ligand and transition metal, e.g., rhodium, recovery and recycling.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: June 18, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: Michael L. Tulchinsky, Ronald R. Peterson
  • Patent number: 8466327
    Abstract: Aldehyde-functionalized polyethers containing thiomethylaldehyde groups are described. Also described is a method of preparing the aldehyde-functionalized polyethers. These functionalized polyethers may be useful for protein conjugation, surface modification, and for the formation of hydrogel adhesives and sealants which are useful for medical applications.
    Type: Grant
    Filed: August 31, 2009
    Date of Patent: June 18, 2013
    Assignee: Actamax Surgical Materials, LLC
    Inventor: Samuel David Arthur
  • Publication number: 20130115661
    Abstract: A method for utilizing cultivated plant biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from cultivated plant biomass for producing derivative products while minimizing waste products.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 9, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Publication number: 20130091759
    Abstract: A method of production of value-added, biobased chemicals, derivative products, and/or purified glycerin from plant-based bioglycerin is described herein. A method of purification of plant-based bioglycerin is also described herein. The method of purification of plant-based bioglycerin described provides methods for desalinating, decolorizing, and/or concentrating plant-based bioglycerin for the production of biobased chemicals, derivative products, and/or purified glycerin.
    Type: Application
    Filed: January 12, 2012
    Publication date: April 18, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Christopher M. Yost
  • Publication number: 20130091760
    Abstract: A method of production of value-added, biobased chemicals, derivative products, and/or purified glycerin from animal-based bioglycerin is described herein. A method of purification of animal-based bioglycerin is also described herein. The method of purification of animal-based bioglycerin described provides methods for desalinating, decolorizing, and/or concentrating animal-based bioglycerin for the production of biobased chemicals, derivative products, and/or purified glycerin.
    Type: Application
    Filed: January 12, 2012
    Publication date: April 18, 2013
    Applicant: Thesis Chemistry, LLC
    Inventors: John R. Peterson, Christopher M. Yost
  • Publication number: 20130078704
    Abstract: Methods of processing chemicals change their structure, and in particular increase their solubility and/or rate of dissolution, for intermediates and products made from the structurally changed materials. Many of the methods provide materials that can be more readily utilized in reactions or other processes to produce useful intermediates and products, e.g., energy, fuels, foods or materials. Chemicals that are treated using the processes described herein can be used to form highly concentrated solutions. Treatment can change the functionality of the chemical, and thus the polarity of the chemical, which may render the treated chemical soluble in solvents in which the untreated chemical is insoluble or only sparingly or partially soluble. Methods may in some cases increase the solubility of the chemical in water or aqueous media. The chemical may be, for example, a solid, liquid, or gel, or mixtures thereof.
    Type: Application
    Filed: November 20, 2012
    Publication date: March 28, 2013
    Applicant: Xyleco, Inc.
    Inventor: Xyleco, Inc.
  • Patent number: 8399399
    Abstract: 3- and 4-Methyl-4-dodecenal, a method of their production and fragrance and flavor compositions comprising at least one of them.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: March 19, 2013
    Assignee: Givaudan SA
    Inventor: Roman Kaiser
  • Publication number: 20130066103
    Abstract: This invention relates to a co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(?0.94(mole % ethylene incorporated)+100), when 10 to 60 mole % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mole % ethylene is present in the co-oligomer, and 3) X=(1.83*(mole % ethylene incorporated)?83), when 70 to 90 mole % ethylene is present in the co-oligomer. This invention also relates to a homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum. This invention also relates to a process of making homo-oligomer, comprising propylene, wherein the productivity is greater than 4500 g/mmol Hf (or Zr)/hour.
    Type: Application
    Filed: November 6, 2012
    Publication date: March 14, 2013
    Applicant: ExxonMobil Chemical Patents Inc.
    Inventors: Patrick BRANT, Donna J. CROWTHER, Andrew G. NARVAEZ
  • Patent number: 8394978
    Abstract: A compound comprising a sulfonated triorganophosphine of formula R1R2PR3[SO3M)]n, wherein R1 and R2 are selected individually from alkyl, aralkyl, and alicyclic groups; wherein R3 represents a branched divalent or polyvalent, alkylene or alicyclic radical that is bonded to the phosphorus atom and to one or more sulfonate substituents, and further wherein R3 does not contain any aryl moieties; M represents a monovalent cation; and n is an integer representing a total number of sulfonated substituents. The compound is useful as a ligand in transition metal-ligand complex catalysts that are capable of catalyzing the hydroformylation of an olefinically-unsaturated compound with carbon monoxide and hydrogen to form one or more corresponding aldehyde products. The ligand is incapable of alkyl-aryl exchange, thereby leading to reduced ligand usage and improving ligand and transition metal, e.g., rhodium, recovery and recycling, as compared with prior art ligands.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: March 12, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: Michael L. Tulchinsky, Anthony G. Abatjoglou
  • Publication number: 20130059992
    Abstract: This invention relates to a co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(?0.94 (mole % ethylene incorporated)+100), when 10 to 60 mole % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mole % ethylene is present in the co-oligomer, and 3) X=(1.83*(mole % ethylene incorporated)?83), when 70 to 90 mole % ethylene is present in the co-oligomer. This invention also relates to a homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum. This invention also relates to a process of making homo-oligomer, comprising propylene, wherein the productivity is greater than 4500 g/mmol Hf (or Zr)/hour.
    Type: Application
    Filed: November 6, 2012
    Publication date: March 7, 2013
    Applicant: ExxonMobil Chemical Patents Inc.
    Inventors: Patrick BRANT, Donna J. CROWTHER, Andrew G. NARVAEZ, JR.
  • Publication number: 20130046112
    Abstract: Amido-fluorophosphite compounds and catalyst systems comprising at least one amido-fluorophosphite ligand compound in combination with a transition metal are described. Moreover, the use of amido-fluorophosphite containing catalysts for transition metal catalyzed processes, especially to the hydroformylation of various olefins to produce aldehydes are also described.
    Type: Application
    Filed: August 16, 2011
    Publication date: February 21, 2013
    Applicant: Eastman Chemical Company
    Inventor: Thomas Allen Puckette
  • Publication number: 20130018205
    Abstract: The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closing metathesis of unsymmetric 1,8-dienes whose C—C double bond at the 8 position is nonterminal. Cycloheptene and the cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride conversion products thereof, and the derivatives thereof, are important synthesis units for active ingredient compounds. The ring-closing metathesis is preferably performed as a reactive distillation. The unsymmetric 1,8-dienes for the ring-closing metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation from the corresponding unsaturated carboxylic acids or carboxylic acid derivatives.
    Type: Application
    Filed: July 10, 2012
    Publication date: January 17, 2013
    Applicant: BASF SE
    Inventors: Joaquim Henrique TELES, Michael Limbach, Richard Dehn, Stephan Deuerlein, Manuel Danz
  • Publication number: 20120329696
    Abstract: The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. Such perfume raw materials and compositions, including the delivery systems, disclosed herein expand the perfume communities' options as such perfume raw materials can provide variations on character and such compositions can provide desired odor profiles.
    Type: Application
    Filed: May 24, 2012
    Publication date: December 27, 2012
    Inventors: Hugo Robert Germain Denutte, Johan Smets, An Pintens, Jeanne Alfons Van Aken, Freek Annie Camiel Vrielynck
  • Publication number: 20120317873
    Abstract: A method of hydrothermal hydrocatalytic treating biomass is provided. Lignocellulosic biomass is treated with a digestive solvent to form a pretreated biomass containing soluble carbohydrates. The pretreated biomass is contacted, with hydrogen at a temperature in the range of 150° C. to less than 300° C. in the presence of a pH buffering agent and a supported hydrogenolysis catalyst containing (a) sulfur, (b) Mo or W, and (c) Co, Ni or mixture thereof, incorporated into a suitable support, to form a plurality of oxygenated hydrocarbons.
    Type: Application
    Filed: June 13, 2012
    Publication date: December 20, 2012
    Applicant: SHELL OIL COMPANY
    Inventors: Kimberly Ann JOHNSON, Glenn Charles KOMPLIN, Joseph Broun POWELL, John Anthony SMEGAL
  • Publication number: 20120302516
    Abstract: The invention provides magnetic nanoparticles comprising a core, wherein the nanoparticles comprise at least one therapeutic agent linked to the core via a hydrazone linkage or via an oxime ether linkage, methods for making said nanoparticles, and methods for using said nanoparticles.
    Type: Application
    Filed: October 19, 2010
    Publication date: November 29, 2012
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Michael H. Nantz, Souvik Biswas
  • Patent number: 8282793
    Abstract: The present invention relates to a continuous process for preparing neral (cis-citral) in pure or enriched form by distillatively separating neral from substance mixtures comprising essentially neral and geranial (trans-citral). This distillative separation is performed in a dividing wall column or in a connection of two distillation columns in the form of a thermal coupling.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: October 9, 2012
    Assignee: BASF SE
    Inventors: Gunnar Heydrich, Nawid Kashani-Shirazi, Christoph Jäkel, Joachim Schmidt-Leithoff
  • Publication number: 20120251449
    Abstract: The present invention claims fluoro- & iodo-containing aldehydes as ALDH substrates for use as diagnostic imaging agents or as therapeutic agents. The aldehydes are both directly and indirectly attached to an aromatic or a straight chain ring. ALDH activity was monitored either by the formation of acid-product or consumption of aldehyde substrates.
    Type: Application
    Filed: December 22, 2010
    Publication date: October 4, 2012
    Inventors: Vijaya Raj Kuniyil Kulangara, Alan Cuthbertson, Peter Iveson, Chitralekha Rangaswamy, Veena Rao, Rajiv Bhalla
  • Patent number: 8273313
    Abstract: A system and process for separating methacrolein (MA) from methacrylic acid (MAA) and acetic acid in the gas phase product from partial oxidation of isobutylene (IB) in two oxidation steps is disclosed. The process and system maximize recovery of all three components at minimum capital and energy cost, under conditions that minimize polymerization conditions and plugging by solids deposition in compressors, columns, etc.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: September 25, 2012
    Assignee: Saudi Basic Industries Corporation
    Inventor: Frederick Merrill Galloway
  • Publication number: 20120238486
    Abstract: The invention relates to novel aldehydes and nitriles from isophorone with general formula (I) having a specific fragrance (Formula I) (I), as well as to the use of said compounds in perfumery.
    Type: Application
    Filed: September 17, 2010
    Publication date: September 20, 2012
    Applicant: V. MANE FILS
    Inventors: Agnès Muratore, Jean-Jacques Chanot
  • Publication number: 20120198769
    Abstract: A catalyst-coated support including a sheetlike support, a primer layer applied thereto and composed of nanoparticles composed of silicon oxide-comprising material, and at least one catalyst layer applied to the primer layer. The layers applied are notable for a particularly good adhesive bond strength and can be used particularly efficiently in heterogeneously catalyzed gas phase reactions, especially in microreactors.
    Type: Application
    Filed: June 23, 2010
    Publication date: August 9, 2012
    Inventors: Steffen Schirrmeister, Martin Schmitz-Niederau, Ingo Klüppel, Christoph Filthaut
  • Publication number: 20120172630
    Abstract: A process for removing degradation acids from a catalyst solution comprising a phosphorus-containing hydroformylation ligand used in a hydroformylation reaction is described. The process involves using a supported epoxy compound. Also described is a hydroformylation process that includes the degradation acids removal process.
    Type: Application
    Filed: December 30, 2010
    Publication date: July 5, 2012
    Applicant: Eastman Chemical Company
    Inventor: Yun-Shan Liu
  • Publication number: 20120172337
    Abstract: The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient.
    Type: Application
    Filed: March 8, 2012
    Publication date: July 5, 2012
    Applicant: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Henri Dasseux, Carmen Daniela Oniciu
  • Patent number: 8198486
    Abstract: Disclosed are methods for generating propylene glycol, ethylene glycol and other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols from biomass using hydrogen produced from the biomass. The methods involve reacting a portion of an aqueous stream of a biomass feedstock solution over a catalyst under aqueous phase reforming conditions to produce hydrogen, and then reacting the hydrogen and the aqueous feedstock solution over a catalyst to produce propylene glycol, ethylene glycol and the other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols. The disclosed methods can be run at lower temperatures and pressures, and allows for the production of oxygenated hydrocarbons without the need for hydrogen from an external source.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: June 12, 2012
    Assignee: Virent, Inc.
    Inventor: Randy D. Cortright
  • Publication number: 20120137572
    Abstract: A method is disclosed including co-processing a biomass feedstock and a refinery feedstock in a refinery unit. The method can include producing a liquid product by catalytically cracking or hyrocracking or hydrotreating a biomass feedstock and a refinery feedstock in a refinery unit having a fluidized reactor. Catalytically cracking can include transferring hydrogen from the refinery feedstock to carbon and oxygen from the biomass feedstock. Hydrocracking or hydrotreating can include transferring hydrogen from a hydrogen source to carbon and oxygen from the biomass feedstock, and to carbon from the refinery feedstock.
    Type: Application
    Filed: May 24, 2010
    Publication date: June 7, 2012
    Applicant: KIOR, INC.
    Inventors: Robert Bartek, Steve Yanik, Paul O'Connor
  • Publication number: 20120142918
    Abstract: A caged phosphine product is provided which can act as a ligand to form a metal complex. The metal complex can be used as a catalyst.
    Type: Application
    Filed: January 26, 2010
    Publication date: June 7, 2012
    Inventors: Ranbir Singh Padda, Martin Barry Smith, Gordon Findlay Docherty, Michael John Harrison