Abstract: The invention relates to a biosensor comprising an electrically conductive substrate, with a first layer comprising Ruthenium Purple formed on the substrate, a second layer comprising polyaniline or a derivative thereof comprising one or more non-polar substituents formed on the first layer, and a third layer comprising one or more enzymes trapped within a matrix formed on the second layer. The biosensor is for use in the detection of analytes such as purines and derivatives thereof, particularly in the detection of hypoxanthine.

Abstract: The invention relates to a tonometric measuring head for bringing a measuring medium to a composition consistent with an individual to be examined non-invasively through the outermost tissue layer. A measuring head comprises a sealed chamber, having a wall whose oppositely facing sides are essentially made of pliable membrane materials, at least one membrane material of said materials being permeable to a gas to be analyzed but effectively impermeable at least to solids and liquids, as well as a measuring medium in a cavity within the wall. The measuring head is provided with a guide member between the chamber and an external device. In addition, the chamber wall is partially constituted by a pliable second membrane material which is effectively impermeable both to a gas to be analyzed and to at least solids and liquids.

Abstract: Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.

Abstract: A fetal movement recorder instrument for registering perceived fetal movement includes an actuator operated by the maternal patient to indicate a perceived fetal movement by the maternal patient, the relative intensity, date, and time, so as to provide a corresponding actuator output signal. A data log unit receives and records the perceived fetal movement information over a preset counting period. A start/stop count alarm provides a stop count indication when the preset counting period is over, and a display provides a message corresponding to the number of fetal movement counts over a predetermined time. The recorded information is transmitted from the data log/base station to the care provider's location where feedback information may be transmitted back to the base station at the maternal patient location.

Abstract: A sensor device for measuring the vital parameters of a fetus during birth. The sensor device includes a sensor having a wire spiral for attaching the sensor to the fetus, and a placement device for placing the sensor on a leading part of the fetus. A measuring device is connected to the sensor, and the sensor has on a front side facing the fetus at least one light emitter and at least one receiver which are conductively connected with the measuring device. The conductors are arranged in a cable branching off the sensor towards the measuring device, and the cable is introduced laterally, and essentially tangentially, onto a back surface of the sensor and extending in front of an insertion point into the sensor to form a helical partial winding approximately in a plane that extends approximately perpendicular to a center axis of the wire spiral.

Abstract: An improved fetal pulse oximeter sensor. The friction provided on the sensor head surface to engage the fetus is higher than the friction on the back side of the sensor head. Thus, any contact with a maternal surface by the back side of the sensor head is less likely to dislodge the sensor, since the maternal tissues will slide over the sensor head. The portion of the sensor surface in contact with the fetus' head will not move because of the increased friction. The increased friction can be achieved by using two different materials with different coefficients of friction, or by using a smooth surface on the back of the sensor head, and a rough surface on the sensor face.