Electroanalysis Patents (Class 600/345)
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Patent number: 11350857Abstract: Various analyte sensor systems for controlling activation of analyte sensor electronics circuitry are provided. Related methods for controlling analyte sensor electronics circuitry are also provided. Various analyte sensor systems for monitoring an analyte in a host are also provided. Various circuits for controlling activation of an analyte sensor system are also provided. Analyte sensor systems utilizing a state machine having a plurality of states for collecting a plurality of digital counts and waking a controller responsive to a wake up signal are also provided. Related methods for such analyte sensor systems are also provided. Systems for controlling activation of analyte sensor electronics circuitry utilizing a magnetic sensor are further provided. One or more display device configured to display one or more analyte concentration values are also provided.Type: GrantFiled: May 1, 2019Date of Patent: June 7, 2022Assignee: Dexcom, Inc.Inventors: Jason Halac, Sebastian Bohm, Vincent Peter Crabtree, David DeRenzy, Mark S. Dervaes, Nicholas Kalfas, Zebediah L. McDaniel, Michael Levozier Moore, Todd Andrew Newhouse, Michael A. Ploof, Stephen Alan Reichert, Peter C. Simpson, Alexander Leroy Teeter, Rodolfo Garcia, Jaroslaw Piotrowiak, Thomas George O'Connell, Arlene G. Doria
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Patent number: 11351537Abstract: A method for forming a biological microdevice includes applying a biocompatible coarse scale additive process with an additive device and a biocompatible material to form an object. The coarse scale is a dimension not less than about 100 ?m. The method also includes applying a biocompatible fine scale subtractive process with a subtractive device to the object. The fine scale is a dimension not greater than about 1000 ?m. The method also includes moving the object between the additive device and the subtractive device. A system is also provided for performing the above method and includes the additive device, the subtractive device, a means for transporting the object between the additive device and subtractive device and a processor with a memory including instructions to perform one or more of the above method steps.Type: GrantFiled: February 2, 2018Date of Patent: June 7, 2022Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.Inventors: Swaminathan Rajaraman, Avra Kundu, Tariq Ausaf
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Patent number: 11331019Abstract: Nanoparticle-fibrous membrane composites are provided as tunable interfacial scaffolds for flexible chemical sensors and biosensors by assembling gold nanoparticles (Au NPs) in a fibrous membrane. The gold nanoparticles are functionalized with organic, polymeric and/or biological molecules. The fibrous membranes may include different filter papers, with one example featuring a multilayered fibrous membrane consisting of a cellulose nanofiber (CN) top layer, an electrospun polyacrylonitrile (PAN) nanofibrous midlayer (or alternate material), and a nonwoven polyethylene terephthalate (PET) fibrous support layer, with the nanoparticles provided on the fibrous membranes through interparticle molecular/polymeric linkages and nanoparticle-nanofibrous interactions. Molecular linkers may be employed to tune hydrogen bonding and electrostatic and/or hydrophobic/hydrophilic interactions to provide sensor specificity to gases or liquids. The sensors act as chemiresistor-type sensors.Type: GrantFiled: August 7, 2018Date of Patent: May 17, 2022Assignee: The Research Foundation for The State University of New YorkInventors: Chuan-Jian Zhong, Mark D. Poliks, Benjamin S. Hsiao, Ning Kang, Shan Yan, Jing Li, Shiyao Shan, Jin Luo
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Patent number: 11304664Abstract: A system and method provides a glucose report for determining glycemic risk based on an ambulatory glucose profile of glucose data over a time period, a glucose control assessment based on median and variability of glucose, and indicators of high glucose variability. Time of day periods are shown at which glucose levels can be seen. A median glucose goal and a low glucose line provide coupled with glucose variability provide a view into effects that raising or lowering the median goal would have. Likelihood of low glucose, median glucose compared to goal, and variability of glucose below median provide probabilities based on glucose data. Patterns can be seen and provide guidance for treatment.Type: GrantFiled: December 15, 2020Date of Patent: April 19, 2022Assignee: Abbott Diabetes Care Inc.Inventors: Erwin S. Budiman, Gary A. Hayter, Kenneth J. Doniger, Timothy C. Dunn, Nathan C. Crouther, Glenn Berman, Howard A. Wolpert
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Patent number: 11300561Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.Type: GrantFiled: September 13, 2021Date of Patent: April 12, 2022Assignee: ABBOTT DIABETES CARE, INC.Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
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Patent number: 11298537Abstract: A periocular assembly that is configured to be positioned in the fornix of an eye of the user includes a ring; a plurality of electrodes spaced along the ring; a microcontroller operably coupled to the plurality of electrodes; and a sensor assembly coupled to the ring and operably coupled to the microcontroller. A method of stimulating a lacrimal gland of the user includes monitoring eye condition(s) using the sensor assembly; determining, based on the monitored eye condition(s) and using the microcontroller, if the monitored eye conditions(s) exceed a predetermined threshold; and activating, using the microcontroller and in response to the monitored eye condition(s) exceeding the predetermined threshold, the plurality of electrodes to stimulate the lacrimal gland of the user.Type: GrantFiled: March 25, 2020Date of Patent: April 12, 2022Assignee: TWENTY TWENTY THERAPEUTICS LLCInventor: Christian Gutierrez
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Patent number: 11295855Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.Type: GrantFiled: November 7, 2017Date of Patent: April 5, 2022Assignee: Dexcom, Inc.Inventors: Andrew Attila Pal, Leif N. Bowman, Eric Cohen, Basab Dattaray, Edward Day, Apurv Ullas Kamath, Aarthi Mahalingam, Dana Minor, Scott A. Moss, Neil Puri, Eli Reihman, Conrad Woods, Laurie L. Berg, Jorge Valdes
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Patent number: 11287648Abstract: A near-eye optic includes a substrate having a clear aperture for propagating light. An inconspicuous electrical circuit is supported by the substrate in the clear aperture of the substrate. The inconspicuous electrical circuit includes a plurality of inconspicuous conductive traces disposed in an inconspicuous pattern and electrically coupled to a plurality of inconspicuous electrical components. The inconspicuous pattern may include e.g. an asymmetric pattern, an aperiodic pattern, a pseudo-random pattern, a meandering pattern, a periodic pattern modulated with pseudo-random perturbations, or a non-rectangular pattern modulated with pseudo-random perturbations.Type: GrantFiled: January 8, 2021Date of Patent: March 29, 2022Assignee: Facebook Technologies, LLCInventors: Karol Constantine Hatzilias, Robin Sharma, Christopher Yuan Ting Liao, Andrew Ouderkirk
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Patent number: 11272866Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.Type: GrantFiled: March 10, 2021Date of Patent: March 15, 2022Assignee: One Drop Biosensor Technologies, LLCInventors: Ashwin Pushpala, Matthew Chapman, Alan Szmodis, Abhijit Ghosh
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Patent number: 11272885Abstract: A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.Type: GrantFiled: July 29, 2020Date of Patent: March 15, 2022Assignee: One Drop Biosensor Technologies, LLCInventors: Ashwin Pushpala, Matthew Chapman, Alan Szmodis
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Patent number: 11266350Abstract: An adhesive patch for attaching at least one EM probe to a subject's body, the adhesive patch comprising a planar member having at least one layer of radiation absorbing material and having at least one opening formed within the radiation absorbing material to allow the propagation of EM radiation via the opening from one side of the planar member to the other. The adhesive patch further comprises at least one layer of an adhesive attached over at least part of a bottom surface of the planar member, which adhesive layer may be applied so as to form a pattern on the bottom surface, the pattern comprising at least one adhesive-covered portion and at least one adhesive-free portion.Type: GrantFiled: May 2, 2013Date of Patent: March 8, 2022Assignee: Sensible Medical Innovations Ltd.Inventors: Amir Saroka, Shlomi Bergida
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Patent number: 11246531Abstract: An exercise feedback system determines muscle fatigue measurements using physiological data generated by a sensor-equipped athletic garment. The muscle fatigue measurement is determined by analyzing the frequency spread of the physiological data. The exercise feedback system may customize exercise programs, determine risks of injury, or generate biofeedback for presentation on graphical user interfaces using the muscle fatigue measurements. The exercise feedback system accesses pre-determined muscle fatigue measurement models that define criteria for the aforementioned features. For instance, if an athlete is becoming fatigued and exercising with improper form based on a muscle fatigue measurement, the exercise feedback system modifies the athlete's exercise program to help target and improve the athlete's weaknesses as well as to prevent injury.Type: GrantFiled: May 10, 2019Date of Patent: February 15, 2022Assignee: Mad Apparel, Inc.Inventors: Lev Korzinov, Ankit Gordhandas, Christopher John Wiebe
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Patent number: 11230469Abstract: The disclosure discloses a drive component of a micro-needle system, a method for driving the same, a micro-needle system and a method for fabricating the same; wherein the drive component includes a substrate with a groove; a bottom electrode in the groove; an electro-active polymer layer, covering the bottom electrode, in the groove; and an upper flexible electrode covering the electro-active polymer layer; wherein the upper flexible electrode and the bottom electrode are configured to generate a voltage, and the electro-active polymer layer is configured to generate a strain under the voltage.Type: GrantFiled: May 16, 2019Date of Patent: January 25, 2022Assignee: BOE Technology Group Co., Ltd.Inventors: Zhidong Wang, Lijia Zhou, Quanguo Zhou, Ronghua Lan, Rongjian Yan
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Patent number: 11232917Abstract: Disclosed is a system for allowing a user to control electrical items. The system includes self-powered contactless one or more switches for controlling the electronic items, and a hub unit capacitively coupled to identify the user operating the one or more switches. The hub unit includes a frequency generator, a first impedance unit, a controller, a first electrode, a modulator, and an interface unit. The switch includes a second electrode, a rectifier, a buffer, a second impedance unit, a logic block, a shift register, and a second modulator. The user interacts with the second electrode to operate the connected electrical items. The interaction results in the change of a variable payload data. The controller identifies the interaction on decoding the change in the variable payload data and further the controller operates the connected electrical items.Type: GrantFiled: April 30, 2021Date of Patent: January 25, 2022Inventors: Wolfgang Richter, Faranak Zadeh
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Patent number: 11213230Abstract: A method for optional external calibration of a calibration-free glucose sensor uses values of measured working electrode current (Isig) and EIS data to calculate a final sensor glucose (SG) value. Counter electrode voltage (Vcntr) may also be used as an input. Raw Isig and Vcntr values may be preprocessed, and low-pass filtering, averaging, and/or feature generation may be applied. SG values may be generated using one or more models for predicting SG calculations. When an external blood glucose (BG) value is available, the BG value may also be used in calculating the SG values. A SG variance estimate may be calculated for each predicted SG value and modulated, with the modulated SG values then fused to generate a fused SG. A Kalman filter, as well as error detection logic, may be applied to the fused SG value to obtain a final SG, which is then displayed to the user.Type: GrantFiled: December 13, 2017Date of Patent: January 4, 2022Assignee: MEDTRONIC MINIMED, INC.Inventors: Jeffrey Nishida, Andrea Varsavsky, Taly G. Engel, Keith Nogueira, Andy Y. Tsai, Peter Ajemba
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Patent number: 11213249Abstract: A blood sugar regulation system including: a blood sugar sensor; an insulin injection device; and a processing and control unit predicting the future evolution of the blood sugar based on a physiological model and accordingly controlling the insulin injection device, wherein the processing and control unit is capable of: a) implementing a calibration of the model by taking into account a history of the measured blood sugar; b) at the end of the calibration step, determining whether the model is satisfactory or not based on at least one numerical indicator representative of the error between the blood sugar estimated based on the model and the real blood sugar measured by the sensor; and c) if the quality of the model is not satisfactory, controlling the insulin injection device without taking into account the predictions made from the model.Type: GrantFiled: September 19, 2017Date of Patent: January 4, 2022Assignee: Commissariat à l'Énergie Atomique et aux Énergies AlternativesInventor: Eléonore Doron
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Patent number: 11191463Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.Type: GrantFiled: May 3, 2021Date of Patent: December 7, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: Steven Scott, Christopher J. Bennell, Claire Bhogal, Katie A. Cranfield, Marc B. Taub, Bree M. Winter, Owen D. Reynolds, Jean-Pierre Babka, Dharmendra S. Patel, Christopher A. Thomas, Udo Hoss, Mark S. Yahnke, Tahir S. Khan
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Patent number: 11185264Abstract: Disclosed are analyte monitoring systems and methods for calibrating an analyte sensor using one or more reference measurements. These systems and methods may include using a conversion function and first sensor data to calculate a first sensor analyte level, weighting a first reference analyte measurement (RM1) and one or more previous reference analyte measurements according to a weighted average cost function, updating the conversion function using the weighted RM1 and the one or more weighted previous reference analyte measurements as calibration points, and using the updated conversion function and second sensor data to calculate a second sensor analyte level. In some aspects, the systems and methods may include updating one or more of lag parameters used to calculate the sensor analyte levels.Type: GrantFiled: September 26, 2018Date of Patent: November 30, 2021Assignee: Senseonics, IncorporatedInventors: Xiaoxiao Chen, Ravi Rastogi, Andrew DeHennis, Patricia Sanchez
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Patent number: 11187591Abstract: The invention relates to the provision of apparatus for use in measuring the temperature of a body of matter and in particular the temperature of a foodstuff in a manner which allows the required apparatus in the form of a housing with data processing means and a temperature probe connected thereto, to be used effectively and without the apparatus itself becoming a safety hazard. This is achieved by using materials which are provided in a form to allow the apparatus, and portions thereof to be rendered detectable by metal detection and/or X-ray detection apparatus.Type: GrantFiled: December 12, 2017Date of Patent: November 30, 2021Inventor: Sean Ronald Smith
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Patent number: 11179071Abstract: Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.Type: GrantFiled: March 23, 2021Date of Patent: November 23, 2021Assignee: ABBOTT DIABETES CARE INCInventors: John C. Mazza, Andrew H. Naegeli, Gary Ashley Stafford
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Patent number: 11179072Abstract: Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.Type: GrantFiled: March 23, 2021Date of Patent: November 23, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: John C. Mazza, Andrew H. Naegeli, Gary Ashley Stafford
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Patent number: 11179107Abstract: The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.Type: GrantFiled: June 1, 2018Date of Patent: November 23, 2021Assignee: I-SENS, INC.Inventors: Kyung Chul Chae, Hyun Ho Choi, Goang Yel Ryu, Ji Hoon Wang, Young Jea Kang
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Patent number: 11177425Abstract: The present disclosure provides a driving backplane, a method for manufacturing the same, and a display device. The driving backplane includes: a substrate; and a bonding layer located on a side of the substrate and configured to bond with a plurality of Micro LEDs arranged in an array, wherein the bonding layer comprises a bonding metal layer and a conductive protection layer that are stacked sequentially along a direction away from the substrate, an orthographic projection of the conductive protection layer on the substrate substantially coinciding with an orthographic projection of the bonding metal layer on the substrate.Type: GrantFiled: March 23, 2020Date of Patent: November 16, 2021Assignees: Ordos Yuansheng Optoelectronics Co., Ltd., BOE Technology Group Co., Ltd.Inventors: Feng Li, Yezhou Fang
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Patent number: 11163016Abstract: A leakage current sensor and a leakage current monitoring device; the leakage current center comprising an input end, an output end and an ASIC chip; the ASIC chip is electrically connected with the input end for reading analog quantity signals of the input end; the ASIC chip is further electrically connected to a digital signal processing module; the digital signal processing module can output digital quantity signals to the output end; the digital signal processing module can simultaneously feedback the output digital quantity signals to the ASIC chip, thereby forming a closed-loop feedback circuit; the input end of the leakage current sensor comprises a current sampling unit; a reference unit is arranged between the current sampling unit and the ASIC chip.Type: GrantFiled: March 17, 2017Date of Patent: November 2, 2021Inventor: Quan Chen
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Patent number: 11152294Abstract: An article includes a glass or glass-ceramic substrate having a first major surface and a second major surface opposite the first major surface, and at least one via extending through the substrate from the first major surface to the second major surface over an axial length in an axial dimension. The article also includes a metal connector disposed within the via that hermetically seals the via. The article has a helium hermeticity of less than or equal to 1.0×10?8 atm-cc/s after 1000 thermal shock cycles, each of the thermal shock cycle comprises cooling the article to a temperature of ?40° C. and heating the article to a temperature of 125° C., and the article has a helium hermeticity of less than or equal to 1.0×10?8 atm-cc/s after 100 hours of HAST at a temperature of 130° C. and a relative humidity of 85%.Type: GrantFiled: April 5, 2019Date of Patent: October 19, 2021Assignee: Corning IncorporatedInventors: Tian Huang, Mandakini Kanungo, Ekaterina Aleksandrovna Kuksenkova, Prantik Mazumder, Chad Byron Moore, Chukwudi Azubuike Okoro, Ah-Young Park, Scott Christopher Pollard, Rajesh Vaddi
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Patent number: 11135368Abstract: A method and device for using insulin sensitivity values to estimate the distribution of future insulin sensitivity values for a given patient based on dimensional relationships between current, prior and delta insulin sensitivity values, and observed future insulin sensitivity values for similar patients or subjects, or based on an individual patient or subject's historical values.Type: GrantFiled: April 16, 2019Date of Patent: October 5, 2021Assignee: TIRO Medical LimitedInventors: James Geoffrey Chase, Jennifer Launa Knopp, Christopher Grant Pretty, Vincent Uyttendaele
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Patent number: 11129550Abstract: One embodiment provides a method, including: obtaining, at an information handling device, at least one physiological data point that corresponds to a physiological metric associated with a user; determining, using a processor, an activity type of the user; determining, using a processor, whether the at least one physiological data point is outside a threshold range for the physiological metric based on the activity type; and providing, responsive to determining that the at least one physiological data point is outside the threshold range, a notification. Other aspects are described and claimed.Type: GrantFiled: March 28, 2018Date of Patent: September 28, 2021Assignee: Lenovo (Singapore) Pte. Ltd.Inventors: John Weldon Nicholson, Daryl Cromer
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Patent number: 11116428Abstract: A biosensor is for sensing analytes in a fluid. The biosensor may include a first structural layer having a first hydrogel, a second structural layer having a second hydrogel, and a bioactive region extending between the first structural layer and the second structural layer and having a third hydrogel. The biosensor may include a first electrode coupled to the bioactive region, and a second electrode coupled to the first structural layer and being spaced apart from the bioactive region. The second structural layer may have a through opening adjacent the bioactive region, and the bioactive region may be configured to be in fluid communication with an environment external to the biosensor for receiving the fluid comprising the analytes.Type: GrantFiled: May 25, 2016Date of Patent: September 14, 2021Assignee: STMICROELECTRONICS S.R.L.Inventors: Helena Iuele, Vincenza Di Palma
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Patent number: 11119090Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.Type: GrantFiled: April 12, 2021Date of Patent: September 14, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
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Patent number: 11103165Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.Type: GrantFiled: March 19, 2021Date of Patent: August 31, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: Thomas A. Peyser, Adam Heller
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Patent number: 11096611Abstract: A method providing a signal quality degree associated with an analyte value measured in a continuous monitoring system is disclosed. The method includes: receiving a measured analyte value from a biosensor; determining at least two impact parameters, wherein each of the impact parameters is influenced by an operational status of the continuous monitoring system and wherein each of the impact parameters is capable of exerting an influence on the signal quality of the biosensor and wherein the influence of each of the impact parameters on the signal quality of the biosensor is expressed by a weight assigned to each of the impact parameters; and determining the signal quality degree associated with the measured analyte value as a function of the weights and the corresponding impact parameters; and providing the signal quality degree associated with the analyte value. A method of calibration using the signal quality degree is also disclosed.Type: GrantFiled: April 23, 2020Date of Patent: August 24, 2021Assignee: Roche Diabetes Care, Inc.Inventor: Christian Ringemann
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Patent number: 11069158Abstract: In an embodiment, the disclosed technologies include an apparatus for storing data and communicating data between a vehicle or an agricultural implement and a computing device. Embodiments include a non-conductive housing, an antenna coupled to the non-conductive housing, an integrated circuit coupled to the antenna, a thermally and electrically conductive housing coupled to the integrated circuit, at least one ground clip coupled to the thermally and electrically conductive housing, at least one other integrated circuit coupled to the at least one ground clip, a memory coupled to the other integrated circuit and arranged to at least temporarily store digital communications between a vehicle or an agricultural implement and the computing device, and a connector communicatively coupled to the memory and arranged to mate with a connector of the vehicle or the agricultural implement.Type: GrantFiled: March 3, 2020Date of Patent: July 20, 2021Assignee: THE CLIMATE CORPORATIONInventors: Samuel Rodriguez, Jongjin Kim, Will Darden, Aaron Peterson
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Patent number: 11064921Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.Type: GrantFiled: July 30, 2018Date of Patent: July 20, 2021Assignee: ABBOTT DIABETES CARE INC.Inventor: Gary Ashley Stafford
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Patent number: 11051870Abstract: A device for compressing a renal artery prior to delivery of radiofrequency ablative energy to the renal nerves. The device includes a stent structure with a focal region that expands outwards to place the RF electrodes located on the stent structure in close proximity to the renal nerves. A covering is applied to the stent structure to prevent intimal hyperplasia.Type: GrantFiled: June 7, 2018Date of Patent: July 6, 2021Inventors: William Joseph Drasler, William Joseph Drasler, II
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Patent number: 11045125Abstract: An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes: a housing, the housing comprising a first opening; a skin interface member disposed in the first opening, the skin interface member comprising an inner member having a second opening, and an outer member at least partially surrounding the inner member and attached to the first opening; and at least one skin-penetration member configured and arranged to project within the second opening. Arrangements having alternatively constructed skin interface members are also described.Type: GrantFiled: November 29, 2017Date of Patent: June 29, 2021Assignee: Intuity Medical, Inc.Inventors: Raul Escutia, Craig M. Litherland, Jeffrey L. Emery, Jeffrey M. Jones, Michael F. Tomasco, Kelley J. Lipman
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Patent number: 11020061Abstract: A first vital signs information detecting sensor and a second vital signs information sensor are attached to a living body. The first vital signs information detecting sensor detects over time first vital signs information and first motion information of the living body. The first vital signs information and the first motion information are transmitted from the first vital signs information detecting sensor to a receiver. The second vital signs information detecting sensor detects over time second vital signs information and second motion information of the living body. The second vital signs information and the second motion information are transmitted from the second vital signs information detecting sensor to the receiver. The first vital signs information and the second vital signs information are displayed on a display of the receiver in a synchronized state, on the basis of the first motion information and the second motion information.Type: GrantFiled: July 24, 2018Date of Patent: June 1, 2021Assignee: NIHON KOHDEN CORPORATIONInventors: Norihito Konno, Yosuke Nagasawa
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Patent number: 11013432Abstract: A medical device (110) for detecting at least one analyte in a body fluid, a method of using a medical device (110) and a method for assembling a medical device are disclosed.Type: GrantFiled: August 3, 2017Date of Patent: May 25, 2021Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube, Helmut Walter, Klaus Cornelius
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Patent number: 10987040Abstract: Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.Type: GrantFiled: June 13, 2017Date of Patent: April 27, 2021Assignee: DexCom, Inc.Inventors: Michael J. Estes, Stephen J. Vanslyke, Apurv Ullas Kamath, Thomas A. Peyser, Lucas Bohnett, Aarthi Mahalingam, Arturo Garcia, Peter C. Simpson, Anna Leigh Davis, Sebastian Böhm
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Patent number: 10976304Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.Type: GrantFiled: November 23, 2020Date of Patent: April 13, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
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Patent number: 10973449Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.Type: GrantFiled: September 11, 2020Date of Patent: April 13, 2021Assignee: ABBOTT DIABETES CARE INC.Inventor: Gary Ashley Stafford
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Patent number: 10973443Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.Type: GrantFiled: April 26, 2018Date of Patent: April 13, 2021Assignee: ABBOTT DIABETES CARE INC.Inventors: Jeffery V. Funderburk, Duane O. Yamaski, Brian VanHiel, Stephen J. Flynn
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Patent number: 10966644Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.Type: GrantFiled: September 11, 2020Date of Patent: April 6, 2021Assignee: ABBOTT DIABETES CARE INC.Inventor: Gary Ashley Stafford
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Patent number: 10959653Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.Type: GrantFiled: September 11, 2020Date of Patent: March 30, 2021Assignee: ABBOTT DIABETES CARE INC.Inventor: Gary Ashley Stafford
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Patent number: 10955687Abstract: A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.Type: GrantFiled: July 20, 2017Date of Patent: March 23, 2021Assignee: Johnson & Johnson Vision Care, Inc.Inventor: Milburn Muthu
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Patent number: 10952652Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.Type: GrantFiled: March 18, 2019Date of Patent: March 23, 2021Assignee: Abbott Diabetes Care Inc.Inventors: Thomas A. Peyser, Adam Heller
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Patent number: 10940554Abstract: Methods of fabricating a probe are described. In an example, a structure may be formed on a surface of a substrate. The structure may include the probe, a hinge, and an anchor arranged linearly, where an angle is formed between the probe and the hinge. The hinge may be positioned between the probe and the anchor, and the structure may be parallel to the substrate. An amount of solder may be deposited on an area of the structure that spans from a portion of the probe to a portion of the anchor, and across the hinge. The deposited solder may be reshaped by an execution of a solder reflow process. The reshape of the deposited solder may cause the probe to rotate about the hinge in order to reduce the angle between the probe and the hinge.Type: GrantFiled: November 30, 2018Date of Patent: March 9, 2021Assignee: International Business Machines CorporationInventors: Li-Wen Hung, Jui-Hsin Lai, Chia-Yu Chen, Ko-Tao Lee
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Patent number: 10905363Abstract: The present invention relates to a point-of-care (POC) diagnostic device adaptable to environmental changes and a control method thereof. The POC diagnostic device includes a measurement unit configured to perform a POC diagnosis, an information acquisition unit configured to acquire environmental information of the POC diagnostic device, and a control unit configured to predict a temperature of the measurement unit on the basis of the environmental information acquired by means of the information acquisition unit and correct a measurement value of the measurement unit or control the POC diagnostic device on the basis of the predicted temperature of the measurement unit.Type: GrantFiled: October 24, 2017Date of Patent: February 2, 2021Assignee: Osang Healthcare Co., Ltd.Inventor: Keun Young Kim
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Patent number: 10898113Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.Type: GrantFiled: June 5, 2018Date of Patent: January 26, 2021Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria E. Carr-Brendel, Paul V. Goode, Jr., Apurv Ullas Kamath, James Patrick Thrower, Ben Xavier
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Patent number: 10891053Abstract: Computerized systems and methods facilitate preventing dangerous blood glucose levels using a predictive model to predict whether a particular patient is trending to have dangerous blood glucose levels. The predictive model may be built using logistic or linear regression models incorporating glucose data associated with a plurality of patients received from a plurality of sources. The glucose data may include context data and demographic data associated with the glucose data and the plurality of patients. The predictive model may be employed to predict a likelihood of a particular patient to have dangerous blood glucose levels. Based on the likelihood, the prediction and one or more interventions are communicated to a care team or the patient. The one or more interventions may be incorporated into a clinical device workflow associated with a clinician on the care team or the patient.Type: GrantFiled: September 13, 2018Date of Patent: January 12, 2021Assignee: CERNER INNOVATION, INCInventors: Hugh H. Ryan, Megan Kathleen Quick, Daniel Craig Crough
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Patent number: 10877909Abstract: A data processing system includes a memory system including a memory device storing data and a controller performing a data program operation or a data read operation with the memory device, and a host suitable for requesting the data program operation or the data read operation from the memory system. The controller can perform a serial communication to control a memory which is arranged outside the memory system and engaged with the host.Type: GrantFiled: March 28, 2019Date of Patent: December 29, 2020Assignee: SK hynix Inc.Inventor: Jong-Min Lee