Electroanalysis Patents (Class 600/345)
  • Patent number: 11350857
    Abstract: Various analyte sensor systems for controlling activation of analyte sensor electronics circuitry are provided. Related methods for controlling analyte sensor electronics circuitry are also provided. Various analyte sensor systems for monitoring an analyte in a host are also provided. Various circuits for controlling activation of an analyte sensor system are also provided. Analyte sensor systems utilizing a state machine having a plurality of states for collecting a plurality of digital counts and waking a controller responsive to a wake up signal are also provided. Related methods for such analyte sensor systems are also provided. Systems for controlling activation of analyte sensor electronics circuitry utilizing a magnetic sensor are further provided. One or more display device configured to display one or more analyte concentration values are also provided.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: June 7, 2022
    Assignee: Dexcom, Inc.
    Inventors: Jason Halac, Sebastian Bohm, Vincent Peter Crabtree, David DeRenzy, Mark S. Dervaes, Nicholas Kalfas, Zebediah L. McDaniel, Michael Levozier Moore, Todd Andrew Newhouse, Michael A. Ploof, Stephen Alan Reichert, Peter C. Simpson, Alexander Leroy Teeter, Rodolfo Garcia, Jaroslaw Piotrowiak, Thomas George O'Connell, Arlene G. Doria
  • Patent number: 11351537
    Abstract: A method for forming a biological microdevice includes applying a biocompatible coarse scale additive process with an additive device and a biocompatible material to form an object. The coarse scale is a dimension not less than about 100 ?m. The method also includes applying a biocompatible fine scale subtractive process with a subtractive device to the object. The fine scale is a dimension not greater than about 1000 ?m. The method also includes moving the object between the additive device and the subtractive device. A system is also provided for performing the above method and includes the additive device, the subtractive device, a means for transporting the object between the additive device and subtractive device and a processor with a memory including instructions to perform one or more of the above method steps.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: June 7, 2022
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Swaminathan Rajaraman, Avra Kundu, Tariq Ausaf
  • Patent number: 11331019
    Abstract: Nanoparticle-fibrous membrane composites are provided as tunable interfacial scaffolds for flexible chemical sensors and biosensors by assembling gold nanoparticles (Au NPs) in a fibrous membrane. The gold nanoparticles are functionalized with organic, polymeric and/or biological molecules. The fibrous membranes may include different filter papers, with one example featuring a multilayered fibrous membrane consisting of a cellulose nanofiber (CN) top layer, an electrospun polyacrylonitrile (PAN) nanofibrous midlayer (or alternate material), and a nonwoven polyethylene terephthalate (PET) fibrous support layer, with the nanoparticles provided on the fibrous membranes through interparticle molecular/polymeric linkages and nanoparticle-nanofibrous interactions. Molecular linkers may be employed to tune hydrogen bonding and electrostatic and/or hydrophobic/hydrophilic interactions to provide sensor specificity to gases or liquids. The sensors act as chemiresistor-type sensors.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: May 17, 2022
    Assignee: The Research Foundation for The State University of New York
    Inventors: Chuan-Jian Zhong, Mark D. Poliks, Benjamin S. Hsiao, Ning Kang, Shan Yan, Jing Li, Shiyao Shan, Jin Luo
  • Patent number: 11304664
    Abstract: A system and method provides a glucose report for determining glycemic risk based on an ambulatory glucose profile of glucose data over a time period, a glucose control assessment based on median and variability of glucose, and indicators of high glucose variability. Time of day periods are shown at which glucose levels can be seen. A median glucose goal and a low glucose line provide coupled with glucose variability provide a view into effects that raising or lowering the median goal would have. Likelihood of low glucose, median glucose compared to goal, and variability of glucose below median provide probabilities based on glucose data. Patterns can be seen and provide guidance for treatment.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: April 19, 2022
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Erwin S. Budiman, Gary A. Hayter, Kenneth J. Doniger, Timothy C. Dunn, Nathan C. Crouther, Glenn Berman, Howard A. Wolpert
  • Patent number: 11300561
    Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: April 12, 2022
    Assignee: ABBOTT DIABETES CARE, INC.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
  • Patent number: 11298537
    Abstract: A periocular assembly that is configured to be positioned in the fornix of an eye of the user includes a ring; a plurality of electrodes spaced along the ring; a microcontroller operably coupled to the plurality of electrodes; and a sensor assembly coupled to the ring and operably coupled to the microcontroller. A method of stimulating a lacrimal gland of the user includes monitoring eye condition(s) using the sensor assembly; determining, based on the monitored eye condition(s) and using the microcontroller, if the monitored eye conditions(s) exceed a predetermined threshold; and activating, using the microcontroller and in response to the monitored eye condition(s) exceeding the predetermined threshold, the plurality of electrodes to stimulate the lacrimal gland of the user.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: April 12, 2022
    Assignee: TWENTY TWENTY THERAPEUTICS LLC
    Inventor: Christian Gutierrez
  • Patent number: 11295855
    Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: April 5, 2022
    Assignee: Dexcom, Inc.
    Inventors: Andrew Attila Pal, Leif N. Bowman, Eric Cohen, Basab Dattaray, Edward Day, Apurv Ullas Kamath, Aarthi Mahalingam, Dana Minor, Scott A. Moss, Neil Puri, Eli Reihman, Conrad Woods, Laurie L. Berg, Jorge Valdes
  • Patent number: 11287648
    Abstract: A near-eye optic includes a substrate having a clear aperture for propagating light. An inconspicuous electrical circuit is supported by the substrate in the clear aperture of the substrate. The inconspicuous electrical circuit includes a plurality of inconspicuous conductive traces disposed in an inconspicuous pattern and electrically coupled to a plurality of inconspicuous electrical components. The inconspicuous pattern may include e.g. an asymmetric pattern, an aperiodic pattern, a pseudo-random pattern, a meandering pattern, a periodic pattern modulated with pseudo-random perturbations, or a non-rectangular pattern modulated with pseudo-random perturbations.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: March 29, 2022
    Assignee: Facebook Technologies, LLC
    Inventors: Karol Constantine Hatzilias, Robin Sharma, Christopher Yuan Ting Liao, Andrew Ouderkirk
  • Patent number: 11272866
    Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: March 15, 2022
    Assignee: One Drop Biosensor Technologies, LLC
    Inventors: Ashwin Pushpala, Matthew Chapman, Alan Szmodis, Abhijit Ghosh
  • Patent number: 11272885
    Abstract: A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: March 15, 2022
    Assignee: One Drop Biosensor Technologies, LLC
    Inventors: Ashwin Pushpala, Matthew Chapman, Alan Szmodis
  • Patent number: 11266350
    Abstract: An adhesive patch for attaching at least one EM probe to a subject's body, the adhesive patch comprising a planar member having at least one layer of radiation absorbing material and having at least one opening formed within the radiation absorbing material to allow the propagation of EM radiation via the opening from one side of the planar member to the other. The adhesive patch further comprises at least one layer of an adhesive attached over at least part of a bottom surface of the planar member, which adhesive layer may be applied so as to form a pattern on the bottom surface, the pattern comprising at least one adhesive-covered portion and at least one adhesive-free portion.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: March 8, 2022
    Assignee: Sensible Medical Innovations Ltd.
    Inventors: Amir Saroka, Shlomi Bergida
  • Patent number: 11246531
    Abstract: An exercise feedback system determines muscle fatigue measurements using physiological data generated by a sensor-equipped athletic garment. The muscle fatigue measurement is determined by analyzing the frequency spread of the physiological data. The exercise feedback system may customize exercise programs, determine risks of injury, or generate biofeedback for presentation on graphical user interfaces using the muscle fatigue measurements. The exercise feedback system accesses pre-determined muscle fatigue measurement models that define criteria for the aforementioned features. For instance, if an athlete is becoming fatigued and exercising with improper form based on a muscle fatigue measurement, the exercise feedback system modifies the athlete's exercise program to help target and improve the athlete's weaknesses as well as to prevent injury.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: February 15, 2022
    Assignee: Mad Apparel, Inc.
    Inventors: Lev Korzinov, Ankit Gordhandas, Christopher John Wiebe
  • Patent number: 11230469
    Abstract: The disclosure discloses a drive component of a micro-needle system, a method for driving the same, a micro-needle system and a method for fabricating the same; wherein the drive component includes a substrate with a groove; a bottom electrode in the groove; an electro-active polymer layer, covering the bottom electrode, in the groove; and an upper flexible electrode covering the electro-active polymer layer; wherein the upper flexible electrode and the bottom electrode are configured to generate a voltage, and the electro-active polymer layer is configured to generate a strain under the voltage.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: January 25, 2022
    Assignee: BOE Technology Group Co., Ltd.
    Inventors: Zhidong Wang, Lijia Zhou, Quanguo Zhou, Ronghua Lan, Rongjian Yan
  • Patent number: 11232917
    Abstract: Disclosed is a system for allowing a user to control electrical items. The system includes self-powered contactless one or more switches for controlling the electronic items, and a hub unit capacitively coupled to identify the user operating the one or more switches. The hub unit includes a frequency generator, a first impedance unit, a controller, a first electrode, a modulator, and an interface unit. The switch includes a second electrode, a rectifier, a buffer, a second impedance unit, a logic block, a shift register, and a second modulator. The user interacts with the second electrode to operate the connected electrical items. The interaction results in the change of a variable payload data. The controller identifies the interaction on decoding the change in the variable payload data and further the controller operates the connected electrical items.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: January 25, 2022
    Inventors: Wolfgang Richter, Faranak Zadeh
  • Patent number: 11213230
    Abstract: A method for optional external calibration of a calibration-free glucose sensor uses values of measured working electrode current (Isig) and EIS data to calculate a final sensor glucose (SG) value. Counter electrode voltage (Vcntr) may also be used as an input. Raw Isig and Vcntr values may be preprocessed, and low-pass filtering, averaging, and/or feature generation may be applied. SG values may be generated using one or more models for predicting SG calculations. When an external blood glucose (BG) value is available, the BG value may also be used in calculating the SG values. A SG variance estimate may be calculated for each predicted SG value and modulated, with the modulated SG values then fused to generate a fused SG. A Kalman filter, as well as error detection logic, may be applied to the fused SG value to obtain a final SG, which is then displayed to the user.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: January 4, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Jeffrey Nishida, Andrea Varsavsky, Taly G. Engel, Keith Nogueira, Andy Y. Tsai, Peter Ajemba
  • Patent number: 11213249
    Abstract: A blood sugar regulation system including: a blood sugar sensor; an insulin injection device; and a processing and control unit predicting the future evolution of the blood sugar based on a physiological model and accordingly controlling the insulin injection device, wherein the processing and control unit is capable of: a) implementing a calibration of the model by taking into account a history of the measured blood sugar; b) at the end of the calibration step, determining whether the model is satisfactory or not based on at least one numerical indicator representative of the error between the blood sugar estimated based on the model and the real blood sugar measured by the sensor; and c) if the quality of the model is not satisfactory, controlling the insulin injection device without taking into account the predictions made from the model.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: January 4, 2022
    Assignee: Commissariat à l'Énergie Atomique et aux Énergies Alternatives
    Inventor: Eléonore Doron
  • Patent number: 11191463
    Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: December 7, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Steven Scott, Christopher J. Bennell, Claire Bhogal, Katie A. Cranfield, Marc B. Taub, Bree M. Winter, Owen D. Reynolds, Jean-Pierre Babka, Dharmendra S. Patel, Christopher A. Thomas, Udo Hoss, Mark S. Yahnke, Tahir S. Khan
  • Patent number: 11185264
    Abstract: Disclosed are analyte monitoring systems and methods for calibrating an analyte sensor using one or more reference measurements. These systems and methods may include using a conversion function and first sensor data to calculate a first sensor analyte level, weighting a first reference analyte measurement (RM1) and one or more previous reference analyte measurements according to a weighted average cost function, updating the conversion function using the weighted RM1 and the one or more weighted previous reference analyte measurements as calibration points, and using the updated conversion function and second sensor data to calculate a second sensor analyte level. In some aspects, the systems and methods may include updating one or more of lag parameters used to calculate the sensor analyte levels.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: November 30, 2021
    Assignee: Senseonics, Incorporated
    Inventors: Xiaoxiao Chen, Ravi Rastogi, Andrew DeHennis, Patricia Sanchez
  • Patent number: 11187591
    Abstract: The invention relates to the provision of apparatus for use in measuring the temperature of a body of matter and in particular the temperature of a foodstuff in a manner which allows the required apparatus in the form of a housing with data processing means and a temperature probe connected thereto, to be used effectively and without the apparatus itself becoming a safety hazard. This is achieved by using materials which are provided in a form to allow the apparatus, and portions thereof to be rendered detectable by metal detection and/or X-ray detection apparatus.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: November 30, 2021
    Inventor: Sean Ronald Smith
  • Patent number: 11179071
    Abstract: Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: November 23, 2021
    Assignee: ABBOTT DIABETES CARE INC
    Inventors: John C. Mazza, Andrew H. Naegeli, Gary Ashley Stafford
  • Patent number: 11179072
    Abstract: Method and system for providing analyte sensor alignment and retention mechanism for improved connectivity with a transmitter unit for electrical connection, and further including transmitter unit contact pins with metal components to improve electrical conductivity with the analyte sensor in an analyte monitoring and management system is provided.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: November 23, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: John C. Mazza, Andrew H. Naegeli, Gary Ashley Stafford
  • Patent number: 11179107
    Abstract: The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: November 23, 2021
    Assignee: I-SENS, INC.
    Inventors: Kyung Chul Chae, Hyun Ho Choi, Goang Yel Ryu, Ji Hoon Wang, Young Jea Kang
  • Patent number: 11177425
    Abstract: The present disclosure provides a driving backplane, a method for manufacturing the same, and a display device. The driving backplane includes: a substrate; and a bonding layer located on a side of the substrate and configured to bond with a plurality of Micro LEDs arranged in an array, wherein the bonding layer comprises a bonding metal layer and a conductive protection layer that are stacked sequentially along a direction away from the substrate, an orthographic projection of the conductive protection layer on the substrate substantially coinciding with an orthographic projection of the bonding metal layer on the substrate.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: November 16, 2021
    Assignees: Ordos Yuansheng Optoelectronics Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Feng Li, Yezhou Fang
  • Patent number: 11163016
    Abstract: A leakage current sensor and a leakage current monitoring device; the leakage current center comprising an input end, an output end and an ASIC chip; the ASIC chip is electrically connected with the input end for reading analog quantity signals of the input end; the ASIC chip is further electrically connected to a digital signal processing module; the digital signal processing module can output digital quantity signals to the output end; the digital signal processing module can simultaneously feedback the output digital quantity signals to the ASIC chip, thereby forming a closed-loop feedback circuit; the input end of the leakage current sensor comprises a current sampling unit; a reference unit is arranged between the current sampling unit and the ASIC chip.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: November 2, 2021
    Inventor: Quan Chen
  • Patent number: 11152294
    Abstract: An article includes a glass or glass-ceramic substrate having a first major surface and a second major surface opposite the first major surface, and at least one via extending through the substrate from the first major surface to the second major surface over an axial length in an axial dimension. The article also includes a metal connector disposed within the via that hermetically seals the via. The article has a helium hermeticity of less than or equal to 1.0×10?8 atm-cc/s after 1000 thermal shock cycles, each of the thermal shock cycle comprises cooling the article to a temperature of ?40° C. and heating the article to a temperature of 125° C., and the article has a helium hermeticity of less than or equal to 1.0×10?8 atm-cc/s after 100 hours of HAST at a temperature of 130° C. and a relative humidity of 85%.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: October 19, 2021
    Assignee: Corning Incorporated
    Inventors: Tian Huang, Mandakini Kanungo, Ekaterina Aleksandrovna Kuksenkova, Prantik Mazumder, Chad Byron Moore, Chukwudi Azubuike Okoro, Ah-Young Park, Scott Christopher Pollard, Rajesh Vaddi
  • Patent number: 11135368
    Abstract: A method and device for using insulin sensitivity values to estimate the distribution of future insulin sensitivity values for a given patient based on dimensional relationships between current, prior and delta insulin sensitivity values, and observed future insulin sensitivity values for similar patients or subjects, or based on an individual patient or subject's historical values.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: October 5, 2021
    Assignee: TIRO Medical Limited
    Inventors: James Geoffrey Chase, Jennifer Launa Knopp, Christopher Grant Pretty, Vincent Uyttendaele
  • Patent number: 11129550
    Abstract: One embodiment provides a method, including: obtaining, at an information handling device, at least one physiological data point that corresponds to a physiological metric associated with a user; determining, using a processor, an activity type of the user; determining, using a processor, whether the at least one physiological data point is outside a threshold range for the physiological metric based on the activity type; and providing, responsive to determining that the at least one physiological data point is outside the threshold range, a notification. Other aspects are described and claimed.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: September 28, 2021
    Assignee: Lenovo (Singapore) Pte. Ltd.
    Inventors: John Weldon Nicholson, Daryl Cromer
  • Patent number: 11116428
    Abstract: A biosensor is for sensing analytes in a fluid. The biosensor may include a first structural layer having a first hydrogel, a second structural layer having a second hydrogel, and a bioactive region extending between the first structural layer and the second structural layer and having a third hydrogel. The biosensor may include a first electrode coupled to the bioactive region, and a second electrode coupled to the first structural layer and being spaced apart from the bioactive region. The second structural layer may have a through opening adjacent the bioactive region, and the bioactive region may be configured to be in fluid communication with an environment external to the biosensor for receiving the fluid comprising the analytes.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: September 14, 2021
    Assignee: STMICROELECTRONICS S.R.L.
    Inventors: Helena Iuele, Vincenza Di Palma
  • Patent number: 11119090
    Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: September 14, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
  • Patent number: 11103165
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: August 31, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Thomas A. Peyser, Adam Heller
  • Patent number: 11096611
    Abstract: A method providing a signal quality degree associated with an analyte value measured in a continuous monitoring system is disclosed. The method includes: receiving a measured analyte value from a biosensor; determining at least two impact parameters, wherein each of the impact parameters is influenced by an operational status of the continuous monitoring system and wherein each of the impact parameters is capable of exerting an influence on the signal quality of the biosensor and wherein the influence of each of the impact parameters on the signal quality of the biosensor is expressed by a weight assigned to each of the impact parameters; and determining the signal quality degree associated with the measured analyte value as a function of the weights and the corresponding impact parameters; and providing the signal quality degree associated with the analyte value. A method of calibration using the signal quality degree is also disclosed.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: August 24, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Christian Ringemann
  • Patent number: 11069158
    Abstract: In an embodiment, the disclosed technologies include an apparatus for storing data and communicating data between a vehicle or an agricultural implement and a computing device. Embodiments include a non-conductive housing, an antenna coupled to the non-conductive housing, an integrated circuit coupled to the antenna, a thermally and electrically conductive housing coupled to the integrated circuit, at least one ground clip coupled to the thermally and electrically conductive housing, at least one other integrated circuit coupled to the at least one ground clip, a memory coupled to the other integrated circuit and arranged to at least temporarily store digital communications between a vehicle or an agricultural implement and the computing device, and a connector communicatively coupled to the memory and arranged to mate with a connector of the vehicle or the agricultural implement.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: July 20, 2021
    Assignee: THE CLIMATE CORPORATION
    Inventors: Samuel Rodriguez, Jongjin Kim, Will Darden, Aaron Peterson
  • Patent number: 11064921
    Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: July 20, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventor: Gary Ashley Stafford
  • Patent number: 11051870
    Abstract: A device for compressing a renal artery prior to delivery of radiofrequency ablative energy to the renal nerves. The device includes a stent structure with a focal region that expands outwards to place the RF electrodes located on the stent structure in close proximity to the renal nerves. A covering is applied to the stent structure to prevent intimal hyperplasia.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: July 6, 2021
    Inventors: William Joseph Drasler, William Joseph Drasler, II
  • Patent number: 11045125
    Abstract: An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes: a housing, the housing comprising a first opening; a skin interface member disposed in the first opening, the skin interface member comprising an inner member having a second opening, and an outer member at least partially surrounding the inner member and attached to the first opening; and at least one skin-penetration member configured and arranged to project within the second opening. Arrangements having alternatively constructed skin interface members are also described.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: June 29, 2021
    Assignee: Intuity Medical, Inc.
    Inventors: Raul Escutia, Craig M. Litherland, Jeffrey L. Emery, Jeffrey M. Jones, Michael F. Tomasco, Kelley J. Lipman
  • Patent number: 11020061
    Abstract: A first vital signs information detecting sensor and a second vital signs information sensor are attached to a living body. The first vital signs information detecting sensor detects over time first vital signs information and first motion information of the living body. The first vital signs information and the first motion information are transmitted from the first vital signs information detecting sensor to a receiver. The second vital signs information detecting sensor detects over time second vital signs information and second motion information of the living body. The second vital signs information and the second motion information are transmitted from the second vital signs information detecting sensor to the receiver. The first vital signs information and the second vital signs information are displayed on a display of the receiver in a synchronized state, on the basis of the first motion information and the second motion information.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: June 1, 2021
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Norihito Konno, Yosuke Nagasawa
  • Patent number: 11013432
    Abstract: A medical device (110) for detecting at least one analyte in a body fluid, a method of using a medical device (110) and a method for assembling a medical device are disclosed.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: May 25, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Stephan-Michael Frey, Oliver Kube, Helmut Walter, Klaus Cornelius
  • Patent number: 10987040
    Abstract: Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: April 27, 2021
    Assignee: DexCom, Inc.
    Inventors: Michael J. Estes, Stephen J. Vanslyke, Apurv Ullas Kamath, Thomas A. Peyser, Lucas Bohnett, Aarthi Mahalingam, Arturo Garcia, Peter C. Simpson, Anna Leigh Davis, Sebastian Böhm
  • Patent number: 10976304
    Abstract: Methods for data processing and control for a medical communication system are provided, including determining a sensitivity value for each sensor of a batch of in vivo analyte sensors; determining a sensitivity variation for each sensor of the batch; determining a mean sensitivity based on the sensitivity value determined for each sensor of the batch when it is determined that the determined sensitivity variation does not exceed a tolerance threshold level; associating a sensor code with each sensor of the batch of in vivo analyte sensors when the mean sensitivity is within a predetermined sensitivity range, wherein the sensor code associated with each sensor is based on a characteristic of the associated sensor; and storing the sensor code associated with at least one sensor of the batch configured to generate signals corresponding to monitored analyte level in a memory of a data processing device associated with the sensor.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: April 13, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Gary Alan Hayter, Geoffrey V. McGarraugh, Andrew H. Naegeli, John Charles Mazza, Benjamin Jay Feldman
  • Patent number: 10973449
    Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: April 13, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventor: Gary Ashley Stafford
  • Patent number: 10973443
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: April 13, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Jeffery V. Funderburk, Duane O. Yamaski, Brian VanHiel, Stephen J. Flynn
  • Patent number: 10966644
    Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: April 6, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventor: Gary Ashley Stafford
  • Patent number: 10959653
    Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided. Embodiments include a holder or mounting unit or structure that retains a medical device in a fixed position on a body part of a user or host, such as on the surface of the skin, and/or provides physical and/or electrical coupling to one or more additional components which may be operatively positioned above and/or below the surface of the skin.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: March 30, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventor: Gary Ashley Stafford
  • Patent number: 10955687
    Abstract: A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: March 23, 2021
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventor: Milburn Muthu
  • Patent number: 10952652
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: March 23, 2021
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Thomas A. Peyser, Adam Heller
  • Patent number: 10940554
    Abstract: Methods of fabricating a probe are described. In an example, a structure may be formed on a surface of a substrate. The structure may include the probe, a hinge, and an anchor arranged linearly, where an angle is formed between the probe and the hinge. The hinge may be positioned between the probe and the anchor, and the structure may be parallel to the substrate. An amount of solder may be deposited on an area of the structure that spans from a portion of the probe to a portion of the anchor, and across the hinge. The deposited solder may be reshaped by an execution of a solder reflow process. The reshape of the deposited solder may cause the probe to rotate about the hinge in order to reduce the angle between the probe and the hinge.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: March 9, 2021
    Assignee: International Business Machines Corporation
    Inventors: Li-Wen Hung, Jui-Hsin Lai, Chia-Yu Chen, Ko-Tao Lee
  • Patent number: 10905363
    Abstract: The present invention relates to a point-of-care (POC) diagnostic device adaptable to environmental changes and a control method thereof. The POC diagnostic device includes a measurement unit configured to perform a POC diagnosis, an information acquisition unit configured to acquire environmental information of the POC diagnostic device, and a control unit configured to predict a temperature of the measurement unit on the basis of the environmental information acquired by means of the information acquisition unit and correct a measurement value of the measurement unit or control the POC diagnostic device on the basis of the predicted temperature of the measurement unit.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: February 2, 2021
    Assignee: Osang Healthcare Co., Ltd.
    Inventor: Keun Young Kim
  • Patent number: 10898113
    Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: January 26, 2021
    Assignee: DexCom, Inc.
    Inventors: James H. Brauker, Victoria E. Carr-Brendel, Paul V. Goode, Jr., Apurv Ullas Kamath, James Patrick Thrower, Ben Xavier
  • Patent number: 10891053
    Abstract: Computerized systems and methods facilitate preventing dangerous blood glucose levels using a predictive model to predict whether a particular patient is trending to have dangerous blood glucose levels. The predictive model may be built using logistic or linear regression models incorporating glucose data associated with a plurality of patients received from a plurality of sources. The glucose data may include context data and demographic data associated with the glucose data and the plurality of patients. The predictive model may be employed to predict a likelihood of a particular patient to have dangerous blood glucose levels. Based on the likelihood, the prediction and one or more interventions are communicated to a care team or the patient. The one or more interventions may be incorporated into a clinical device workflow associated with a clinician on the care team or the patient.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: January 12, 2021
    Assignee: CERNER INNOVATION, INC
    Inventors: Hugh H. Ryan, Megan Kathleen Quick, Daniel Craig Crough
  • Patent number: 10877909
    Abstract: A data processing system includes a memory system including a memory device storing data and a controller performing a data program operation or a data read operation with the memory device, and a host suitable for requesting the data program operation or the data read operation from the memory system. The controller can perform a serial communication to control a memory which is arranged outside the memory system and engaged with the host.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: December 29, 2020
    Assignee: SK hynix Inc.
    Inventor: Jong-Min Lee