Abstract: The present invention relates to a device, system and method for automatic and unobtrusive caloric intake detection. The device comprises a respiration input for obtaining a respiration signal indicating the subject's respiration, and an analysis unit for analyzing the obtained respiration signal in the frequency domain by determining one or more respiration signal features from the obtained respiration signal in the frequency domain related to changes in oxidation and by detecting changes of the one or more determined respiration signal features to detect periods of caloric intake by the subject.

Abstract: The present invention relates to a method for improving sleep quality, comprising the steps of measuring pressure by means of sensors in locations distributed by regions of a mattress; calculating the SQI based on the prominent movements detected depending on the time of night; calculating the mean pressure measured by each sensor; calculating the difference between the mean pressure and the pressure measured by that sensor when there is no user on the mattress; calculating the mean pressure difference for each region of the mattress; calculating a weight factor for each region of the mattress; comparing the weight factor with a reference value; varying the configuration of the mattress by increasing or reducing the support level in the regions. The present invention also relates to a related system and mattress.

Abstract: The present system ensures that external noise sources do not taint sensor data recorded about a user's sleep parameters, to reduce false positives and false negatives, and provides a more accurate record of the user's sleep sounds, by cycling on and off noise sources. Additionally, the present system, in one embodiment, may be used to track changes in sound patterns from the user and from the environment. This may lead to early warning of health issues, as well as issues with the devices in the bedroom.

Abstract: The embodiments disclosed herein relate to catheter assemblies. The catheter assemblies can include a multi-lumen catheter, a junction hub, and extension legs. The catheter assemblies can also include a sheath that includes a membrane that is permeable to one or more gases and impermeable to one or more liquids or solids. The catheter assemblies can be configured to deliver food to a patient through a first lumen, and simultaneously vent or aspirate one or more gases from the patient through a second lumen. The catheter assemblies can also include preformed catheters that assume a non-linear three-dimensional shape when in a relaxed state.

Abstract: The invention relates to a detection system for an electronic nose capable of detecting and identifying a set of compounds that can be found in a gaseous sample, the detection system comprises a plurality of cross-reactivity detection sensors (D1, D2, D3, D4, D5, D6, D7) for supplying signals representing the presence of one or more compounds of said set in the gaseous sample, and which is particularly characterised in that the detection system further comprises at least one reference sensor (RI) for supplying a signal representing the measurement noise of the detection system. The detection system further relates to an electronic nose comprising such a detection system.

Abstract: Embodiments herein include gas sampling catheters, systems and related methods. In an embodiment, a gas sampling catheter is included. The catheter can include a catheter shaft having a proximal end and a distal end, the catheter shaft defining a lumen therein. The catheter can include a gas sampling port providing fluid communication between the exterior of the catheter shaft adjacent the distal end of the lumen of the catheter shaft. The catheter can further include a sensor element disposed in fluid communication with the lumen, the sensor element configured to detect a component of a gaseous sample. The sensor element can include a first measurement zone comprising a plurality of discrete binding detectors. Other embodiments are also included herein.

Abstract: There are provided systems and methods for performing mean arterial pressure (MAP) derived prediction of future hypotension. Such a system includes a hardware unit including a hardware processor and a system memory, a hypotension prediction software code stored in the system memory, and a sensory alarm. The hardware processor is configured to execute the hypotension prediction software code to receive MAP data of the living subject, and to transform the MAP data to one or more parameters predictive of a future hypotension event of the living subject. The hardware processor is further configured to execute the hypotension prediction software code to determine a risk score of the living subject corresponding to the probability of the future hypotension event based on at least some of the one or more parameters, and to invoke the sensory alarm if the risk score of the living subject satisfies a predetermined risk criteria.

Abstract: There are provided systems and methods for performing mean arterial pressure (MAP) derived prediction of future hypotension. Such a system includes a hardware unit including a hardware processor and a system memory, a hypotension prediction software code stored in the system memory, and a sensory alarm. The hardware processor is configured to execute the hypotension prediction software code to receive MAP data of the living subject, and to transform the MAP data to one or more parameters predictive of a future hypotension event of the living subject. The hardware processor is further configured to execute the hypotension prediction software code to determine a risk score of the living subject corresponding to the probability of the future hypotension event based on at least some of the one or more parameters, and to invoke the sensory alarm if the risk score of the living subject satisfies a predetermined risk criteria.

Abstract: A non-contact blood circulation detection system and method thereof is provided. The non-contact blood circulation detection system comprises a thermal image acquisition module, a non-contact blood oxygen detection device and an information processing module. The thermal image acquisition module faces to a biological skin and generates a thermal image corresponding to the biological skin when being activated; the non-contact blood oxygen detection device faces to a biological skin and generates a blood oxygen image corresponding to the biological skin when being activated, and the information processing module is in information connection with the thermal image acquisition module and the non-contact blood oxygen detection device so as to receive the thermal image and the blood oxygen image, and generates a blood circulation image on the basis of the thermal image and the blood oxygen image, wherein the blood circulation image is a two-dimensional image.

Abstract: Herein disclosed is a monitor, including: a measurement section that acquires measured values of a plurality of parameters showing a health state of a living body; a classification setting section that classifies a relationship among the measured values of the plurality of parameters into a plurality of types of detection states; a status setting section that respectively assigns any of a plurality of types of alarm statuses to the plurality of types of detection states; a state specifying section that specifies one of the plurality of types of detection states on the basis of the measured values acquired by the measurement section; and an annunciation section that outputs an alarm corresponding to the alarm status assigned to the specified detection state.

Abstract: A multiple-lumen microcatheter tube has at least two tube lumens and a closed distal tube end. In the area of the distal tube end, a separation strip has between the two tube lumens at least one passage opening. There results a multiple-lumen tube, whose use as for example a probe for measuring tissue parameters, is improved.

Abstract: An organ perfusion apparatus may include at least two tubes connected to an organ or tissue. A method of perfusing an organ or tissue may include connecting a first end of each of the at least two tubes to an organ or tissue, applying a fluid motive force to a perfusion fluid in the two tubes to force the fluid through the two tubes into the organ or tissue, and perfusing the organ or tissue through the at least two tubes such that the fluid motive force, provided by, e.g., a pump, and backpressure generated by the organ or tissue, establishes a flow balance between the at least two tubes. The flow balance may be altered without altering the fluid motive force that is applied.

Abstract: The methods of the present invention are based upon the gathering of information from various sources about animals. The information is based upon laboratory testing, genetic analysis and observations by owners and/or trainers about various traits that can be readily observed. Based upon this collection of information, one method generates Performance Index which scores or ranks an animal in terms of how well an animal might function for the intended purpose. Other methods include the ability to selection an optimum breeding pair from one or more stallions and/or one or more mares that would likely produce an offspring with the desired traits.

Abstract: A method includes receiving a first patient data and a second patient data for a time period, wherein the first patient data and the second patient data are measured from a patient. Further, the method includes identifying a plurality of segmented trends in the first patient data and the second patient data as one of an uptrend, a downtrend, and neutral. Furthermore, the method includes classifying at least one segmented trend from the plurality of segmented trends as a pattern. Additionally, the method includes triggering an alarm as an early warning of patient distress based on the pattern.

Abstract: A catheter tip having a spring element that imparts longitudinal flexibility, pushability and radial rigidity to the catheter tip, thereby improving deliverability, is provided. The spring element also provides radial support to the distal edge of the catheter tip. The spring element may taper distally, but may have a substantially constant inner luminal diameter. The spring element may be partially covered or embedded, leaving its distal end exposed. The spring element may also include spaced coils in a proximal region. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

Abstract: Method for Controlling Electrodes for Bio-impedance Measurements and Apparatus for Bio-impedance Measurements There is provided a control circuit for electrodes in a bio-impedance measurement system, the bio-impedance measurement system comprising screening current injecting electrodes and measuring current injecting electrodes, the control circuit comprising: a current generator for connection to at least one screening current injecting electrode; and an measuring signal output configured to establish a measuring potential between the measuring current injecting electrodes, wherein the control circuit is configured such that the measuring potential is dependent on a measure of a potential difference resulting from the screening current. The control circuit uses the value of the potential resulting from the screening current to determine the potential difference between the measuring current injecting electrodes.

Abstract: Present embodiments are directed to a system and method capable of detecting and graphically indicating physiologic patterns in patient data. For example, present embodiments may include a monitoring system that includes a monitor capable of receiving input relating to patient physiological parameters and storing historical data related to the parameters. Additionally, the monitoring system may include a screen capable of displaying the historical data corresponding to the patient physiological parameters. Further, the monitoring system may include a pattern detection feature capable of analyzing the historical data to detect a physiologic pattern in a segment of the historical data and capable of initiating a graphical indication of the segment on the screen when the physiologic pattern is present in the segment.

Abstract: A detection device for simultaneous in-situ measurement of dissolved oxygen at different submerged plant leaf-water interface levels. The detection device includes a dissolved oxygen micro-optrode host. A plurality of detection probes are externally connected to the dissolved oxygen micro-optrode host and can extend out probes. The detection device includes a leaf clamp having an upper clamping head, a lower clamping head, a hinged shaft and a clamping handle. Each of the upper and lower clamping head includes a plurality of water passing cavities penetrating through the back and the front thereof. Each of the upper and lower clamping head includes a plurality of slots horizontally extending inwardly of the corresponding clamping head. The detection device includes a plurality of insertion pieces having a probe groove. The detection probe is locatable in the respective probe groove for fixation. The insertion pieces are insertable and fixable in the slots.

Abstract: A catheter tip having a spring element that imparts longitudinal flexibility, pushability and radial rigidity to the catheter tip, thereby improving deliverability, is provided. The spring element also provides radial support to the distal edge of the catheter tip. The spring element may taper distally, but may have a substantially constant inner luminal diameter. The spring element may be partially covered or embedded, leaving its distal end exposed. The spring element may also include spaced coils in a proximal region. The apparatus may be used with any interventional catheter system, but is particularly suitable for use with balloon-expandable stent systems and balloon-angioplasty systems, where flexibility of the catheter tip and minimal flaring of the distal edge of the catheter tip is desirable.

Abstract: Embodiments of the disclosure are directed to a system for analysis of respiratory distress in hospitalized patients. The system performs multi-parametric simultaneous analysis of respiration rate (RR) and pulse oximetry (SpO2) data trends in order to gauge patterns of patient instability pertaining to respiratory distress. Three patterns in SpO2 and RR are used along with LOWESS algorithm and Chauvenets criteria for outlier rejection to obtain robust short term and long term trends in RR and SpO2. Pattern analysis detects the presence of any one of three pattern types proposed. Further, a learning paradigm is introduced to find unknown instances of respiratory distress. This algorithm in conjunction with the learning model allows early detection of respiratory distress in hospital ward and ICU patients.

Abstract: Described herein is a highly effective route towards the controlled and isotropic reduction in size-scale, of complex 3D structures using silicone network polymer chemistry. In particular, a class of silicone structures were developed that once patterned and cured can ‘shrink’ micron scale additive manufactured and lithographically patterned structures by as much as 1 order of magnitude while preserving the dimensions and integrity of these parts. This class of silicone materials is compatible with existing additive manufacture and soft lithographic fabrication processes and will allow access to a hitherto unobtainable dimensionality of fabrication.

Abstract: An apparatus for treatment of a patient with both sleep-disordered breathing and diabetes includes: a blower configured to provide a supply of air at positive pressure; a patient interface; headgear to hold the patient interface in position in communication with a patient's airways; at least one hypoglycemia sensor; an alarm; and a controller, wherein the controller is programmed to receive a signal from the at least one hypoglycemia detector, analyze the signal for indications of hypoglycemia and upon detection of an indication of hypoglycemia trigger the alarm.

Abstract: An apparatus and method for non-invasive monitoring and detection of sudden changes in cardiovascular hemodynamics, in which a PPG signal is obtained from a patient, a time-frequency spectrum (TFS) is computed from the PPG signal, instantaneous modulations at a plurality of time points defining a curve of a prominent frequency of oscillation are extracted from the TFS, a peak power spectral density sequence is computed using the instantaneous modulations, and instantaneous peak values for following prominent frequency oscillations are monitored.

Abstract: Devices and systems have a sensor probe configured to measure tissue oxygen saturation in the intestine or mesentery. The devices and systems can determine the oxygenation state of the entire thickness of the intestine or mesentery. Thus, embodiments of the invention can be applied in diagnosing intestinal ischemia in a patient, as well as in monitoring tissue oxygen saturation of the intestine or mesentery during or after a surgical procedure.

Abstract: A laparoscopic surgical method comprises obtaining a first instrument comprising an elongate shaft with a distal end and a proximal end connected to a first handle. The distal end of the first instrument is passed through a percutaneous incision. A surgical end effector is obtained having a distal end with operable jaws and a proximal end selectively attachable to and detachable from the distal end of the first instrument. A second instrument is obtained comprising a distal end and a proximal end connected to a second handle. The surgical end effector is loaded ex vivo on the distal end of the second instrument. The distal end of the second instrument with the loaded surgical end effector is passed through a second incision spaced from the percutaneous incision. The proximal end of the surgical end effector is attached in vivo to the distal end of the first instrument. Tissue is manipulated by actuating the handle of the first instrument to operate the jaws of the surgical end effector.

Abstract: Mobile network services are performed in a mobile data network in a way that is transparent to most of the existing equipment in the mobile data network. The mobile data network includes a radio access network and a core network. A breakout component in the radio access network breaks out data coming from a basestation, and hosts edge applications, including third party edge applications, that perform one or more mobile network services at the edge of the mobile data network based on the broken out data.

Abstract: Methods and apparatus for qualifying and quantifying excitation-dependent physiological information extracted from wearable sensors in the midst of interference from unwanted sources are provided. An organism is interrogated with at least one excitation energy, energy response signals from two or more distinct physiological regions are sensed, and these signals are processed to generate an extracted signal. The extracted signal is compared with a physiological model to qualify and/or quantify a physiological property. Additionally, important physiological information can be qualified and quantified by comparing the excitation wavelength-dependent response, measured via wearable sensors, with a physiological model.

Abstract: Various embodiments of an tracheal tube having a sensor coupled to a selectively permeable membrane are provided. In some embodiments, the membrane may be permeable to one or more blood gases and/or blood analytes. Certain embodiments of the endotracheal tube may be capable of deploying the sensor during intubation to sense one or more indicators of blood flow characteristics, such as a level of blood gases and/or blood analytes, in the respiratory tract. Embodiments of the present invention may include positioning of the sensor in a variety of suitable positions with respect to the permeable membrane, such as mounting the sensor to the underside of an inflatable permeable membrane.

Abstract: A system includes a sensor, a second connector, a local processor, a first telemetry module, a second telemetry module, and a remote processor. The sensor is coupled to a cord and the cord has a first connector. The second connector is coupled to a housing. The second connector is configured to mate with the first connector. The local processor is coupled to the second connector and disposed in the housing. The local processor is configured to execute instructions stored in a local memory. The local memory is disposed in the housing. The local processor is configured to generate calculated data based on a signal received at the second connector. The signal corresponds to a parameter measured by the sensor. The first telemetry module is coupled to the local processor and is configured to wirelessly communicate the calculated data. The second telemetry module is configured to communicate with the first telemetry module. The remote processor is coupled to the second telemetry module.

Abstract: Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition of the lung is an acute lung injury. In specific embodiments, the acute lung injury is chemical induced acute lung injury (CIALI). In some embodiments, the methods are provided for treating or protecting a subject from chemical induced acute lung injury that include administering to the subject a therapeutically effective amount of a phosphatase located on chromosome 10 (PTEN) inhibitor such as N(9,10-dioxo-9,10-di-hydrophenanthren-2-yl)pivalamide (SF1670). In some embodiments, the method products a subject from CAILI or reduces CAILI that results from a subsequent exposure to a chemical that induces chemical induced acute lung injury.

Abstract: The disclosure pertains to a perfusion system that is easy to set-up, use and monitor during a bypass procedure. In some embodiments, the disclosure pertains to a perfusion system in which at least some of the disposable components used with the perfusion system are configured to be able to communicate set-up and/or operational parameters to the perfusion system in order to unlock further functionality within the perfusion system.

Abstract: A human body support, such as a chair, has a plurality of support segments that are arranged in an array. Each support segment has a protrusion elevation that is independently variable and controllable in its distance of protrusion elevation against the supported human body. A sensor is connected to a human body on the support and senses a human body parameter that can indicate the presence of drowsiness. A controller analyzes the sensed parameter to detect whether the sensed parameter is within a range indicating the presence of drowsiness. The controller applies a wave of varying segment protrusion elevation against the human body in response to the detection of drowsiness. The wave progresses in a direction from an inferior location on the human body toward a more superior location. Alternatively, a wave of electrical stimuli is applied by similarly positioned electrodes and causes periodic tightening and relaxing of proximate muscles.

Abstract: A heart monitoring system for a person includes one or more wireless nodes; and wearable appliance in communication with the one or more wireless nodes, the appliance monitoring vital signs.

Abstract: A catheter for delivering securing elements to a tissue, such as a blood vessel, and imaging the tissue before, after, or during the imaging. The catheters incorporate intravascular ultrasound (IVUS) imaging, including Focused Acoustic Computed Tomography (FACT), as well as optical coherence tomography (OCT).

Abstract: A regional oximetry system has a display and at least one processor causing a plurality of views to be displayed on the display, each configured to occupy at least a portion of the display. The views are adapted to present data responsive to at least one physiological signal. A first sensor port is configured to receive at least a first physiological signal representative of a regional tissue oxygenation level, and a second sensor port is configured to receive at least a second physiological signal representative of an arterial oxygen saturation level. One view presents a first trend graph of the first physiological signal and a second trend graph of the second physiological signal. An area between the first trend graph and the second trend graph can include a differential analysis of regional-to-central oxygen saturation.

Abstract: This document relates to receiving and processing signals during cardio-pulmonary resuscitation (CPR) treatment. This document further relates to establishing a localized, patient-specific network for communication of information from one or more sensors to a computing device.

Abstract: Disclosed herein are methods, compositions and devices for detecting oxygen in various samples such as environmental and biological samples.

Abstract: Embodiments of the invention pertain to kiosks and home kits capable of providing authenticated health information for purposes of privacy, rewards, or incentives. In an embodiment of the invention, biometric measurement devices coupled with a communications infrastructure implement a system of secure information exchange and enhanced data security. In an embodiment of the invention, a user's communications device such as a cell phone is wirelessly connected through or by the machine to a call center or other responder to allow for consultation when appropriate. In an embodiment of the invention, a security/verification system is built into the kiosk, so as to be able to verify a user's identity.

Abstract: Apparatus and methods for attenuating environmental interference are described. A wearable monitoring apparatus includes a housing configured to be attached to the body of a subject and a sensor module that includes an energy emitter that directs energy at a target region of the subject, a detector that detects an energy response signal—or physiological condition—from the subject, a filter that removes time-varying environmental interference from the energy response signal, and at least one processor that controls operations of the energy emitter, detector, and filter.

Abstract: The present invention provides techniques for non-invasive measurement of blood related parameters based on NMR (nuclei) relaxation techniques carried out using a relatively low constant magnetic field in the range of 0.15 to 0.5 Tesla. A plurality of electromagnetic excitation pulse sequences having relatively low radiofrequencies are applied over a living tissue placed in the magnetic field and blood related parameters of the examined subject are determined using a plurality of nuclear spin echo signals received from the tissue in response to the applied excitation sequences, thereby allowing to improve the accuracy of the obtained signals and substantially reducing the time duration of the process.

Abstract: Various embodiments of methods and systems for continuous transdermal monitoring (“CTM”) are disclosed. One exemplary method for CTM begins by monitoring an output signal from an accelerometer. The accelerometer output signal may indicate acceleration and deceleration of a body part of a user, such as the user's wrist. Based on the accelerometer output signal, it may be determined that the body part of the user has decelerated to a minimum, e.g., substantially zero. With a determination that the body part has decelerated to the minimum, e.g., substantially zero, or has not accelerated beyond the minimum, e.g., substantially zero, the method may determine a reading from a pulse oximeter associated with the accelerometer. Advantageously, the pulse oximetry reading, or a reading from other sensors associated with the accelerometer, may be optimally accurate as motion artifact may be minimized. The pulse oximetry reading may be recorded for later query and/or rendered for the benefit of the user.

Abstract: An anti-fouling sleeve for an endotracheal tube, a method of placement, and the tools for placement. The anti-fouling sleeve occupies the entire length of endotracheal tube, and can be installed permanently or made removable and disposable. The sleeve may be instrumented with sensors and/or a UV light source to reduce and potentially eliminate biofilm formation. Once placed inside the endotracheal tube the sleeve expands to conform to the inner diameter of the tube. After use, any accumulated biofilm on the inner portion of the sleeve is removed leaving the inner portion of the endotracheal tube essentially sterile.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract: A restraint device includes at least one sensor configured to sense at least one parameter associated with the wearer of the restraint device. The sensed parameter may be a physiological parameter of the wearer, or the sensed parameter may be a biological substance, a chemical substance, or a radioactive substance, for example. The restraint device may further include a device communicating with the sensor and configured to store and/or transmit information related to the sensed parameter via Radio Frequency Identification (RFID) communication.

Abstract: A method and system establishing cryptographic communications between a remote device and a medical device, with the medical device having less processing power than the remote device are disclosed. The method may comprise establishing unencrypted communication between the remote device and the medical device, generating an asymmetric key pair by the remote device comprising a public key and a private key, generating a key request message and sending of the key request message together with the public key to the medical device, generating a pre-master key and encryption of the pre-master key with the received public key by the medical device, generating a key response message and sending of the key response message together with the encrypted pre-master key from the medical device to the remote device, decrypting the encrypted pre-master key with the private key by the remote device, and deriving a master key as a symmetric key from the pre-master key.

Abstract: A medical device that can have at least one sensor for obtaining data relating to at least one physiological condition of a patient. Some embodiments of the medical device can include internet communication which can allow the data obtained by the sensor(s) to be transmitted to a computer monitored by either a physician or the patient.

Abstract: The present disclosure includes a pulse oximeter attachment having an accessible memory. In one embodiment, the pulse oximeter attachment stores calibration data, such as, for example, calibration data associated with a type of a sensor, a calibration curve, or the like. The calibration data is used to calculate physiological parameters of pulsing blood.

Abstract: A method for monitoring oxygen saturation that includes the following steps: (i) measuring an oxygen saturation of a target area of a person or animal over time; (ii) measuring an oxygen saturation of a reference area of the person or animal over time; and (iii) classifying the oxygen saturation status of the target area based upon a comparison of the oxygen saturation of the target area relative to the oxygen saturation of the reference area over time.

Abstract: A device for applying a sensor to a measurement site on a patient's skin has a wall arrangement defining an applicator volume above the patient's skin The wall arrangement has a patient's side and a sensor side. At least one gas-permeable membrane separates the applicator volume into a first volume directed to the measuring site at the patient's side of the wall arrangement and a second volume separated from the patient's skin and directed to the sensor side of the wall arrangement.

Abstract: A physiological parameter system has one or more parameter inputs responsive to one or more physiological sensors. The physiological parameter system may also have quality indicators relating to confidence in the parameter inputs. A processor is adapted to combine the parameter inputs, quality indicators and predetermined limits for the parameters inputs and quality indicators so as to generate alarm outputs or control outputs or both.