Abstract: A conductive silicone material for human skin electrode is disclosed. In one embodiment, the conductive silicone material comprises a mixture of silicone and carbon powder such that the mixture has a resistivity of 0.08 to 0.12 ?·m and a Shore A hardness of 50 to 60. In an exemplary embodiment, the mixture comprises 60 to 80 weight percent silicone and 20 to 40 weight percent carbon powder. A sensor for detecting human biological signal using a conductive silicone electrode is also disclosed.

Abstract: The present invention is an apparatus and method for making a polymer patterned electrode for cardiac pacing and sensing. The electrode surface includes a polymer overlayed on an electrode. The polymer layer is patterned to form an electrode surface consisting of a polymer and a conductive metal surface. The electrode can be made of a high or low impedance electrode by changing the conductivity of the polymer. Furthermore, the electrode surface texture can be optimized with a micro pattern that may enhance the biocompatibility. The polymer may be conductive or insulative.

Abstract: A disposable medical probe for detecting a leak of physiological fluid comprising: a support layer, a conductive layer on top of the support layer, the conductive layer comprising two conducting electrodes both placed exclusively on each side of a longitudinal axis, a hydrophilic layer on top of at least a part of the conductive layer, where the conductive layer defines two zones: a proximal zone where two proximal electrode parts being are placed parallel to each other and being spaced apart by a distance d, and a distal zone where two distal electrode parts are symmetrical with respect to said longitudinal axis and are spaced apart from each other by a gap e greater than said distance d.

Abstract: The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. In embodiments, the electrodes include a hydrogel in combination with a pH indicator which changes its color or opacity upon repeated use of the electrode, thereby indicating an appropriate time for changing or replacing the electrode.

Abstract: The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. The electrode includes a substrate and a conductive composition on at least a portion of a surface of the substrate. The conductive composition includes at least one hydrogel and at least one component that precipitates from the hydrogel after repeated use of the electrode, thereby providing an indication to replace the electrode.

Abstract: An implantable medical electrode comprising an electrode substrate having an exterior surface, and a zirconium nitride coating disposed over the exterior surface.

Abstract: A disposable medical probe for detecting a leak of physiological fluid comprising a support layer, a conductive layer on top of the support layer, the conductive layer comprising two conducting electrodes both placed exclusively on each side of a longitudinal axis, the conductive layer defining two zones: a proximal zone with two proximal electrode parts being placed parallel to each other and being spaced apart by a constant distance d, and a distal zone with two distal electrode parts being spaced apart from each other by a gap e greater than said distance d, where the distal zone of the electrodes defines an increase in the gap between the distal parts of the electrodes, followed by a decrease in the gap between the distal parts of the electrodes.

Abstract: Textile-based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The electrodes can further include float yarns and can be configured in a textured or ribbed construction. When incorporated into a garment, the electrodes can be used to monitor biophysical characteristics, such as the garment wearer's heart rate. In addition, two garments with textile based electrodes are disclosed. First, a wrist band for use with a cardiac patient remote monitoring system includes two fabric layers with integral textile-based electrodes. The skin contacting surface of the band includes a conductive region formed as a continuous ring or stripe. A connector links the conductive region to a lead to a device.

Abstract: Implantable hermetically sealed structures and methods for making the same. Devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems are included.

Abstract: Microelectrode assemblies and related methods are disclosed for bio-stimulating and/or bio-sensing a target tissue. The assemblies can include a two-side substrate, an array of microelectrodes, each of the microelectrodes including a nano-wire embedded within the substrate and extending from a proximal end to a distal end and through the substrate, each nano-wire having a diameter preferably less than 1 ?m. The substrate can include portions made of nano-porous material(s) through which the microelectrodes pass. The substrate with the embedded nano-wires can effectively be fluid impermeable. The proximal ends of the nano-wires can be adapted to be connected to an electronic device and the distal ends are adapted to be disposed in a biological environment for bio-stimulating a target tissue and/or bio-sensing activities of the target tissue. Suitable alloys such as platinum, platinum-iridium, and/or other noble-metal-alloyed compositions can be used for the nano-wires.

Abstract: A bioelectrode comprising a skin-side, electrically conducting adhesive layer (7) and a flexible electrical connecting cable (4) which in an electrically insulating cable sheath (5) includes at least one electrical conductor (6), preferably in the form of a braid comprising a plurality of individual wires or conducting individual fibers, wherein the electrode-side end (4a) of the connecting cable (4) is arranged between two thermoplastic layers (2, 3) which are welded together at least region-wise, wherein both thermoplastic layers (2, 3) are electrically conducting and are electrically connected to the electrical conductor (6) of the connecting cable (4).

Abstract: Disclosed is a frequency analyzer for a MEMS based cochlear implant with self power supply. The frequency analyzer for a MEMS based cochlear implant includes: an upper structure including a first substrate, and a nano wire contact portion formed under the first substrate and coated with a high conductivity metal; and a lower structure including a second substrate having a space filled with a fluid and an upper portion of which is opened, a membrane formed on the fluid filled in the space of the second substrate, a first electrode formed on the membrane, and a nano wire formed on the first electrode and having the piezoelectric characteristics related to an arbitrary direction in which the nano wire is grown.

Abstract: Herein disclosed are an electrode and a method for making an electrode having an enhanced electrically effective surface providing an increased signal to noise ratio. The electrode having a metal surface selected from gold, tungsten, stainless steel, platinum, platinum-tungsten, platinum-iridium, and combinations thereof; and an electrically conductive coating on said metal surface, said coating consisting essentially of polymerized pyrrole.

Abstract: An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and second and third electrically conductive materials that are inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material, and the third material is positioned adjacent to and entirely covering a top surface of the second electrically conductive material, and covers a portion of a top surface of the non-conductive substrate surrounding the second electrically conductive material. The electrode further includes a conductive hydrogel positioned adjacent to a portion of a top surface of the third electrically conductive material, but laterally offset from the trace material.

Abstract: A dry electrode for biomedical signal measuring sensor includes a conductive sponge, a conductive fabric, and a thin metal film. The conductive fabric covers the whole conductive sponge, and the thin metal film is disposed on one face of the conductive fabric opposite to the conductive sponge. When using the dry electrode in measuring biomedical signal, it is not necessary to apply a conductive gel on a patient's skin, at where the biomedical signal is to be measured. Without the need of applying the conductive gel, the dry electrode is readily for measuring biomedical signal at any time and can be conveniently used in measuring signal over a long period of time without the problem of an attenuated signal due to gradually becoming dried conductive gel.

Abstract: The present disclosure provides electrodes that possess hydrogels for contacting skin. In embodiments, an electrode of the present disclosure may include a substrate and a conductive composition on at least a portion of a surface of the substrate, the conductive composition including at least one hydrogel and at least one component capable of providing either a cooling or warming sensation upon contact with tissue of a patient. Methods for forming these hydrogels and electrodes are also provided.

Abstract: Textile-based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The electrodes can further include float yarns and can be configured in a textured or ribbed construction. When incorporated into a garment, the electrodes can be used to monitor biophysical characteristics, such as the garment wearer's heart rate. In addition, two garments with textile based electrodes are disclosed. First, a wrist band for use with a cardiac patient remote monitoring system includes two fabric layers with integral textile-based electrodes. The skin contacting surface of the band includes a conductive region formed as a continuous ring or stripe. A connector links the conductive region to a lead to a device.

Abstract: Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprising a first electrically conductive substrate and a biological component. The bioelectrode also comprises a conductive polymer electrically coupling the first electrically conductive substrate and the biological component to define a bioelectrode. The bioelectrode can transmit or receive an electrical signal between the electrically conductive substrate and the biological component and conductive polymer.

Abstract: The present invention relates to sensory for measuring signals on the surface of the skin and for producing sensory. In the sensory in accordance with the invention, the electrode surfaces required for measuring of a signal and/or conductors required for transmitting of a signal have been fastened to the textile material of an outfit or accessory used on the body. In the method in accordance with the invention, the electrode surfaces required for the sensory and/or conductors are added to the textile material of an outfit or accessory used on the body.

Abstract: A method is disclosed of detecting a bioelectrical signal from a subject. The method includes the steps of applying a composite material to a subject wherein the composite material includes a polymeric material and a polar material that is substantially dispersed within the polymeric material; coupling monitoring equipment to the second side of the composite material; permitting the polar material within the polymeric material to respond to the bioelectrical signal within the subject; and detecting a responsive electrical signal from the composite material that is representative of the bioelectrical signal. The polar material exhibits molecular compatibility with the polymeric material such that the polar material neither blooms to a surface of the polymeric material nor crystallizes within the polymeric material, and the composite material has a first side for contacting the subject and a second side.

Abstract: Medical electrodes in embodiments of the teachings may include one or more of the following features: (a) a metallic conductor, (b) the metallic conductor sandwiched between a first dielectric layer adjacent a top surface of the metallic conductor and a second dielectric layer located on a bottom surface of the metallic conductor, (c) a conducive gel coating on at least one of the first and second dielectric layers, (e) the metallic conductor, the dielectric layers, and the conductive gel being wrapped to form a multi-tiered electrode having a plurality of conductive surfaces, (f) an adhesive adhering the metallic conductor with the dielectric layers, (g) a tab connector to provide a connection to electrical monitoring equipment and (h) an attachment connector to provide electrical connection with a patient.

Abstract: Textile-based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The electrodes can further include float yarns and can be configured in a textured or ribbed construction. When incorporated into a garment, the electrodes can be used to monitor biophysical characteristics, such as the garment wearer's heart rate.

Abstract: Two garments with textile based electrodes are disclosed. First, a wrist band for use with a cardiac patient remote monitoring system includes two fabric layers with integral textile-based electrodes. The textile based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The skin contacting surface of the band includes a conductive region formed as a continuous ring or stripe. A connector links the conductive region to a lead to a device. Second, an infant garment includes textile based electrodes at the torso region and optionally at other regions in order to monitor the infant's biophysical characteristics as the garment is worn.

Abstract: The present invention discloses a flexible probe structure comprises at least one electrode using a CNT layer as the electrode interface. The CNT layer disposed on the electrode surface is processed with an UV-ozone treatment to form a great number of carbon-oxygen functional groups on the surface of CNT. The carbon-oxygen functional groups can greatly reduce the interface impedance of the electrode and the biological tissue fluid. Thereby, the measurement can achieve better quality. The present invention also discloses a method for fabricating a flexible probe structure, which comprises steps: preparing a flexible substrate; forming a conductive layer on the flexible substrate, and defining an electrode, a wire and a metal pad on the conductive layer; forming a CNT layer on the electrode; forming an insulating layer on the conductive layer to insulate the wire from the environment; and processing the CNT layer with an UV-ozone treatment.

Abstract: An implantable lead for a medical device with an isolated contact connection for connecting a conductor to a contact reduces the opportunity for conductor material to migrate to a contact or into a patient. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, at least one coupling. The lead has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact.

Abstract: The invention relates to a method for monitoring an arrangement for determining a concentration of an analyte in a body fluid. The determination of the concentration of the analyte by means of the arrangement involves a procedure in which the analyte from the body fluid passes through an interface and is transported in a stream of liquid into a flowmeter chamber, in which a measurement is carried out to determine the concentration of the analyte. The evaluation of the measurement takes place in a signal processor. The monitoring of the arrangement comprises the following steps: measurement of measured values of at least two correlated system parameters of the arrangement by means of a sensor system, and comparison of the measured values with limit values stored for each of the system parameters in a storage unit, to obtain a combination of at least two comparison results.

Abstract: Polymer materials form electrode array bodies for neural stimulation, especially for retinal stimulation to create vision. The method lays down a polymer layer. Apply a metal layer to the polymer and pattern to create electrodes and leads. Apply a second polymer layer over the metal layer and pattern to leave openings for electrodes. The array and its supply cable are a single body. A method for manufacturing a flexible circuit electrode array, is: deposit a metal trace layer on an insulator polymer base layer; apply a layer of photoresist on the metal trace layer and pattern the metal trace layer and form metal traces on the insulator polymer base layer; activate the insulator polymer base layer and deposit a top insulator polymer layer and form a single insulating polymer layer with the base insulator polymer layer; wherein the insulator polymer layers are heated at 80-150° C. and then at 230-350° C.

Abstract: An electrode surface coating and method for manufacturing the electrode surface coating comprising a conductive substrate; a surface coating of platinum having a rough configuration and an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape of the electrode. A method for electroplating an electrode surface with platinum coating having a rough surface, comprising electroplating the surface of a conductive substrate at a rate such that the metal particles form on the conductive substrate faster than necessary to form shiny platinum and slower than necessary to form platinum black.

Abstract: The present invention relates to a dry physiological recording electrode that can be used without skin preparation or the use of electrolytic gels. The dry physiological recording electrode comprising a substrate having an upper and a lower surface, and at least one penetrator(s) protruding from the upper surface of the substrate. The penetrator(s) is capable of piercing through the stratum corneum or outer layer of the skin, and transmitting an electric potential from the lower layers of the epidermis through the penetrator(s) which can be measured, or detecting agents from the lower layers of the epidmermis primarily the stratum germinativum layer. At least one epidermis stop may be provided resulting in the formation of detritus troughs interposed between adjacent penetrator(s) and epidermis stops. The present invention also includes a method of sensing biopotentials in the skin.

Abstract: A biomedical sensor is disclosed that includes a conductive material for coupling to monitoring equipment, and a composite. The composite includes a polymeric material and a polar material that is substantially dispersed within the polymeric material. The composite has a first side that is coupled to the conductive material and has a second side that is positionable with respect to a subject to be monitored. The polar material exhibits molecular compatibility with the polymeric material such that the polar material neither blooms to a surface of the polymeric material nor crystallizes within the polymeric material.

Abstract: An electrode arrangement for low artifact electrocardiogram (ECG) monitoring and defibrillation, comprises at least one conductor print line body having a large silver conductor print line area functioning as a defibrillation area and a small silver-silver chloride (Ag/AgCl) conductor print line area functioning as a sensing area, at least one non halide defibrillation gel layer and halide containing sensing gel layer configured to attach with the defibrillation area and sensing area respectively, and at least one insulated conductive ink line for connecting the conductor print line body to a cable that provides an electrical communication between the conductor print line body and an external equipment. When direct current runs through the conductor print line body, the large silver conductor print line area polarizes and the small Ag/AgCl conductor print line area does not polarize so that small Ag/AgCl conductor print line area senses ECG signal leading to low motion artifact.

Abstract: Unique electrodes and/or electrical lead assemblies are provided for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways. The electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue. Each device is coupled to or incorporates nanotube structures or materials therein. Methods for fabricating, deploying, and operating such medical devices are also provided.

Abstract: A flexible dry electrode and the manufacturing method thereof are provided. The electrode has an electroplated uneven surface and at least one hole and is made of porous material.

Abstract: A method is disclosed of detecting an output signal that is representative of an alternating electrical signal from a subject. The method includes the steps of: providing a monitoring sensor on the subject, wherein the monitoring sensor includes a conductive element and a composite material that includes a polar material that is substantially dispersed within a polymeric material; receiving the alternating electrical signal from the subject such that the composite changes its dielectric constant responsive to alternately ascending and collapsing voltages of the alternating electric signal from the subject; and providing an output signal via the conductive element responsive to changes in the dielectric constant of the composite that are representative of the alternating electric signal from the subject.

Abstract: An active implantable medical device (AIMD). The AIMD comprises an electronics module; and a knitted electrode assembly comprising: at least one biocompatible, electrically non-conductive filament arranged in substantially parallel rows each stitched to an adjacent row, and at least one biocompatible, electrically conductive filament intertwined with the at least one non-conductive filament, and configured to be electrically connected to the electronics module.

Abstract: An active implantable medical device (AIMD). The AIMD comprises: a knitted electrode assembly comprising: at least one biocompatible, electrically non-conductive filament arranged in substantially parallel rows each stitched to an adjacent row, and at least one biocompatible, electrically conductive filament having a first end intertwined with a first row of the at least one non-conductive filament, and a second end intertwined with a second row of the at least one non-conductive filament, wherein the first and second rows are spaced from one another.

Abstract: An alternating current responsive composite is disclosed. The composite includes a polymeric material and a polar material that is substantially dispersed within the polymeric material. The polar material is responsive to the presence of an alternating current.

Abstract: An apparatus and method for detecting physiological function, for example, nerve conduction, is described. In one embodiment the apparatus includes a housing including a stimulator shaped to fit a first anatomical site and a detector shaped to fit a second anatomical site. The housing automatically positions the detector substantially adjacent to the second anatomical site when the stimulator is positioned substantially adjacent to the first anatomical site. The detector contains a plurality of individual detection elements, whereby the response evoked by stimulation at the first anatomical site is measured using one or more of these detection elements at the second anatomical location.

Abstract: A leakage current on a side surface of a sensor chip of a cell electrophysiological sensor is reduced. In order to do so, a sensor chip having a continuity hole and a chip holding part covering the side surface of the sensor chip are provided. The sensor chip includes silicon as a main component, and the chip holding part is made of glass. The chip holding part is adhesively bonded to the side surface of the sensor chip by glass welding. Thus, in the cell electrophysiological sensor device of the present invention, the airtightness between the side surface of the sensor chip and the chip holding part is improved, so that a leakage current can be reduced.

Abstract: The present disclosure provides electrodes that possess components capable of indicating to an end-user when the electrode is in need of replacement. In embodiments, the electrodes include a hydrogel in combination with a pH indicator which changes its color or opacity upon repeated use of the electrode, thereby indicating an appropriate time for changing or replacing the electrode.

Abstract: The present invention relates generally to medical devices; in particular and without limitation, to unique electrodes and/or electrical lead assemblies for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways; and, wherein said electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue, and wherein each said device is coupled to or incorporates nanostructure or materials therein. The present invention also provides methods for fabricating, deploying, and operating such medical devices.

Abstract: A lead assembly includes a lead body and at least one cables at least partially disposed within the lead body. The cable has a non-electrode portion and an electrode portion, where the non-electrode portion extends within the lead body, and the electrode portion is external to the lead body.

Abstract: A multi electrode catheter for non contact mapping of the heart having independent articulation and deployment features.

Abstract: An electrode arrangement (10) comprises a knitted electrically conductive electrode portion (12) containing electrically conductive yarn and at least one portion (14) of moisture impermeable electrically conductive material attached to the electrode portion (12). During use the electrode portion (12) and portion of material (14) are applied to a wearers skin. The moisture impermeable material portion (14) is of silicon loaded with carbon black. The moisture impermeable portion (14) encourages perspiration of a user and the perspiration trapped between the skin and moisture impermeable portion (14) reduces skin to electrode contact resistance to increase efficiency of detection of user heart rate or other electrical signals generated by a user.

Abstract: An electrode for applying electric fields to a patient includes a plurality of ceramic elements (e.g., ceramic discs) that are designed to be positioned against the patient's skin. Electrical connections are made to the ceramic elements (e.g., using a flex circuit). Temperature sensors (e.g., thermistors) are preferably provided at at least some of the ceramic elements to sense the temperature at the skin beneath the ceramic elements, so that appropriate action can be taken if an overtemperature condition is detected.

Abstract: The present invention relates to a dry physiological recording electrode that can be used without skin preparation or the use of electrolytic gels. The dry physiological recording electrode comprising a substrate having an upper and a lower surface, and at least one penetrator(s) protruding from the upper surface of the substrate. The penetrator(s) is capable of piercing through the stratum corneum or outer layer of the skin, and transmitting an electric potential from the lower layers of the epidermis through the penetrator(s) which can be measured, or detecting agents from the lower layers of the epidmermis primarily the stratum germinativum layer. At least one epidermis stop may be provided resulting in the formation of detritus troughs interposed between adjacent penetrator(s) and epidermis stops. The present invention also includes a method of sensing biopotentials in the skin.

Abstract: An electrophysiological sensor, weak electrical signal conditioning circuit and method for controlling the circuit as provided. The sensor includes rigid filiform conducting nanostructures connected to a conducting substrate and operable to penetrate an organic tissue. The circuit includes an instrumentation amplifier with an input connected to a first electrode in contact with a first area of a medium, and a second input; a voltage generating device connected to an electrode in contact with a second area of the medium for applying a continuous reference signal to it; a compensator, electrically insulated from the device, for compensating the direct current offsets of a weak electrical signal received by the first electrode, generating a signal with a reference voltage with a value which can be modified by a control system, and supplying it to the second input. A method is also provided for controlling the circuit.

Abstract: Textile-based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The electrodes can further include float yarns and can be configured in a textured or ribbed construction. When incorporated into a garment, the electrodes can be used to monitor biophysical characteristics, such as the garment wearer's heart rate.

Abstract: An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q? ratio of at least 5 as defined by the equation Q ? = W W W G wherein WG is the dry weight of the hydrophilic polymer and WW is weight of water in the sample after absorption of the electrolyte fluid comprising water and an electrolyte salt. The surface contact element can consist essentially of the hydrophilic polymer swollen by the electrolyte fluid. Another electrode system includes a contact element including a crosslinked hydrophilic polymer matrix. The contact element has a Q? ratio of at least 5 as defined by the equation Q ? = W W W G . The contact elements can also have a Q? ratio of at least 6, at least 7, at least 10 or even at least 11.

Abstract: Electrodes include a coating that provides a barrier to fluids and ions within a biological environment. The coating increases the overpotential of the electrode. The coating permits the introduction and use of the electrodes into biological environments without the detrimental complications of electro-chemical reactions typically present with the use of metal and metal-alloy electrodes in such environments.