Combined With Therapeutic Or Diverse Diagnostic Device Patents (Class 600/411)
  • Patent number: 10722124
    Abstract: The invention describes a method for extracting several physiological parameters such as cardiac cycle parameters with one single measurement over a time period and for monitoring mechanical and electrical cardiac activity. The invention finds its use in providing continuous monitoring of heart mechanical and electrical activities over time. Such signal may be transmitted to clinics of family doctors to keep track of the subject's health.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: July 28, 2020
    Assignee: United Arab Emirates University
    Inventors: Mahmoud F. Y. Al Ahmad, Nabil Bastaki, Bisni Fahad Mon
  • Patent number: 10716471
    Abstract: To make it possible to improve user convenience, provided is a control device including: a control unit configured to control a position and an attitude of a microscope unit by driving an arm unit that supports the microscope unit on the basis of a captured image of an operating site photographed by the microscope unit during an operation so that a position and attitude condition set before the operation is satisfied. The position and attitude condition is a condition that prescribes a position and an attitude of the microscope unit with respect to the operating site to obtain a desired captured image corresponding to the position and attitude condition.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: July 21, 2020
    Assignee: SONY CORPORATION
    Inventors: Tomoyuki Ootsuki, Atsushi Miyamoto
  • Patent number: 10702238
    Abstract: The disclosure relates to a system and method for calibrating a medical system. The method may include one or more of the following operations. Projection data of a phantom comprising a plurality of markers may be acquired from an imaging device, at a plurality of angles of a source of the imaging device. A plurality of projection matrices of a first coordinate system relating to the phantom and a transformation matrix between the first coordinate system and a second coordinate system relating to the imaging device may be determined based on the projection data of the phantom and coordinates of the plurality of markers in the first coordinate system. A plurality of projection matrices of the second coordinate system may be determined based on the plurality of projection matrices of the first coordinate system and the transformation matrix.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: July 7, 2020
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Hongcheng Yang, Supratik Bose
  • Patent number: 10699434
    Abstract: A method is disclosed for determining result data based upon medical measurement data of an examination object. Within the method, a high-dimensional first parameter space is formed, in which measurement values of the various measurements are represented with the aid of value tuples. The measurement values of the various measurements are assigned to a value tuple based on their spatial arrangement in the examination object and/or on their temporal arrangement relative to one another. In the first parameter space, the value tuples are analyzed, using at least one mapping function to at least one further parameter space including a lower dimension than the first parameter space, in order to obtain result data. Furthermore, the result data is output, preferably visualized. In addition, a corresponding device for determining result data is described.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: June 30, 2020
    Assignee: SIEMENS HEALTHCARE GMBH
    Inventors: Robert Grimm, Bernd Schweizer
  • Patent number: 10695122
    Abstract: This disclosure relates to forming a lesion in a patient's neurological tissue without requiring general anesthesia. The lesion can be either temporary or permanent. In either case, the lesion can be created by a steerable probe that includes a steerable guide, a laser device, and at least one electrode. The steerable guide steers the probe to a target location in the subject's neurological tissue. When the probe reaches the target location, the laser can create the lesion. The at least one electrode can detect a progressive vanishing of neural activity from the portion of the neurological tissue due to the lesion.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: June 30, 2020
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Jorge Gonzalez-Martinez, Imad Najm, John T. Gale, Karl West
  • Patent number: 10694974
    Abstract: Example embodiments of system and method for magnetic resonance imaging (MRI) techniques for planning, real-time monitoring, control, and post-treatment assessment of high intensity focused ultrasound (HIFU) mechanical fractionation of biological material are disclosed. An adapted form of HIFU, referred to as “boiling histotripsy” (BH), can be used to cause mechanical fractionation of biological material. In contrast to conventional HIFU, which cause pure thermal ablation, BH can generate therapeutic destruction of biological tissue with a degree of control and precision that allows the process to be accurately measured and monitored in real-time as well as the outcome of the treatment can be evaluated using a variety of MRI techniques. Real-time monitoring also allow for real-time control of BH.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: June 30, 2020
    Assignees: UNIVERSITY OF WASHINGTON, KONINKLIJKE PHILIPS N.V.
    Inventors: Ari Partanen, Vera Khokhlova, Navid Farr, Donghoon Lee, Wayne Kreider, Tatiana Khokhlova, Adam Maxwell, Yak-Nam Wang, George Schade, Michael Bailey
  • Patent number: 10687784
    Abstract: A system for insertion of a surgical tool along a trajectory to a target region in a patient's tissues, under the guidance of ultrasound imaging. The system includes a hand-held robot to whose base the probe of an ultrasound system is rigidly connected. The activated platform of the hand held robot carries a surgical tool guide. The alignment of the tool guide defines the trajectory which the tool takes within the subject's body. The position of the target region seen on the ultrasound display, can be recorded, and the robot coordinate frame of reference registered thereto. The system aligns the pose of the robot such that the surgical tool is aimed directly at the target region, independently of motion of the ultrasound probe and its associated robot. An inertial measurement unit can be incorporated to provide back-up positional information if the image of the lesion is lost.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: June 23, 2020
    Assignee: MAZOR ROBOTICS LTD.
    Inventor: Moshe Shoham
  • Patent number: 10682526
    Abstract: The present disclosure discloses a device for controlling rotation of a radiotherapy equipment, for controlling rotation of at least one rotational load of the radiotherapy equipment about a rotation axis. The device and the radiotherapy equipment form a full-closed-loop structure.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: June 16, 2020
    Assignee: OUR NEW MEDICAL TECHNOLOGIES
    Inventor: Xiaojun Yue
  • Patent number: 10668300
    Abstract: Radiation treatment planning and administration can include a Monte Carlo computer simulation tool to simulate photo-generated electrons in tissue. In the simulation, electrons that have left tissue voxels and entered air voxels can be evaluated to identify electrons that are circling along a spiraling trajectory in the air voxels. After at least one full spiraling circumference or other specified distance has been traversed using a detailed electron transport model, a simpler linear ballistic motion model can be instituted. This speeds simulation while accurately accounting for spiraling electrons that re-enter tissue voxels.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: June 2, 2020
    Assignee: Elekta, Inc.
    Inventors: Sami Hissoiny, Michel Moreau
  • Patent number: 10649056
    Abstract: Embodiments can provide a computer-implemented method for free breathing three dimensional diffusion imaging, the method comprising initiating, via a k-space component processor, diffusion/T2 preparation, comprising generating diffusion contrast; and adjusting one or more of amplitude, duration, and polarity to set a first order moment; applying, via an image data processor, a stack of stars k-space ordering, comprising acquiring a radial/spiral view for all members of a plurality of partitions in a partition-encoding direction; increasing an azimuthal angle until a complete set of radial/spiral views are sampled; and applying diffusion gradients along each of three axis simultaneously; and calculating, via the image data processor, an apparent diffusion coefficient map.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: May 12, 2020
    Assignees: Siemens Healthcare GmbH, Cedars-Sinai Medical Center
    Inventors: Xiaoming Bi, Christopher T. Nguyen, Zhaoyang Fan, Yutaka Natsuaki, Debiao Li, Gerhard Laub
  • Patent number: 10639447
    Abstract: A system for monitoring anesthetic agents fill level in a vaporizer reservoir includes a camera configured to capture an image containing a sight glass on the vapor reservoir, just like, a processor, and an agent level module. The agent level module is executable to locate a sight glass portion within the image, an agent level edge within the sight glass portion, and minimum and maximum reference points within the image. A fill percentage is calculated based on a position of the agent level edge relative to the minimum and maximum reference points, and the remaining agent information is calculated based on the fill percentage and the known volume of the vaporizer reservoir.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: May 5, 2020
    Assignee: General Electric Company
    Inventors: James Hanrahan, Antti Tanner
  • Patent number: 10624710
    Abstract: Devices, systems, and methods for measuring the distance and/or depth to a target bone for surgery using a robotic surgical system. The surgical robot system may be configured to depict the distance from a guide tube of the robot to a target bone of a patient as a vector. The vector may represent a view of the guide tube when the guide tube's central axis is coincident with a line of intersection of two viewplanes of a 2D image of the target bone, for example, one viewplane being sagittal and one viewplane being axial.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: April 21, 2020
    Assignee: Globus Medical, Inc.
    Inventors: Neil Crawford, Chris Major
  • Patent number: 10617892
    Abstract: A method for generating a radiation dose map of a dosimeter indicating a spatial distribution of radiation dose imparted to the dosimeter. The corrected radiation dose map may be generated with the computer system by applying temporal correction factor and spatial correction factors to a measured radiation dose map, the corrected radiation dose map having pixel values associated with the measured radiation dose having been corrected for temporal effects caused by changes in the measure of radiation dose imparted to the dosimeter between the first time point and the second time point, and for spatial effects caused by the sensitivity of the dosimeter to radiation measurements as a function of the spatial dimension.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: April 14, 2020
    Assignee: Duke University
    Inventors: Mark Oldham, Stewart Biedeman Mein, IV
  • Patent number: 10610304
    Abstract: In some embodiments, a synthetic (virtual) orthopedic treatment device (e.g. a virtual external fixator representing a physical fixator attachable to a patient anatomic structure) is displayed concurrently in two views (e.g. anterior-posterior and lateral) along corresponding digital medical images (e.g. X-rays), and rotation/translation user input received along one of the images is used to concurrently control both displays of the orthopedic treatment device to reflect the rotation/translation user input.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: April 7, 2020
    Assignee: Stryker European Holdings I, LLC
    Inventor: Andrew Haskell
  • Patent number: 10607358
    Abstract: An ear shape analysis method implemented by a computer includes generating a first ear shape data set by applying a first principal component weight vector to an ear shape model reflecting statistical tendencies of three-dimensional shapes of ears; and identifying from the generated first ear shape data set an estimated three-dimensional shape of a target ear corresponding to a target ear image represented by image data.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 31, 2020
    Assignee: Yamaha Corporation
    Inventor: Shoken Kaneko
  • Patent number: 10602958
    Abstract: A virtual tracking system for a virtual medical device. The virtual medical device may include a tangible proximal portion that at least temporarily has a magnetic element attached thereto. The system includes a tracking circuit configured to track movement of the virtual medical device and a display. The tracking circuit may include at least one reception component configured to detect a magnetic field of the magnetic element and to generate magnetic field strength data. The tracking circuit may also include a processor that iteratively computes position data of a virtual distal portion of the virtual medical device according to the magnetic field strength data so as to simulate insertion of the virtual distal portion of the virtual medical device into a body of a patient. The display may be configured to depict an image of the computed position data of the virtual distal portion of the virtual medical device.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: March 31, 2020
    Assignee: C. R. Bard, Inc.
    Inventors: Fred E. Silverstein, Robert N. Golden
  • Patent number: 10605882
    Abstract: Systems and methods for performing diffusion-weighted magnetic resonance imaging (“MRI”), including reconstructing and analyzing images, while preserving phase information that is traditionally discarded in such applications, are provided. For instance, background phase variations are eliminated, which enables complex-valued data analysis without the usual noise bias. As a result, the systems and methods described here provide an image reconstruction that enables true signal averaging, which increases signal-to-noise ratio (“SNR”) and allows higher contrast in diffusion model reconstructions without a magnitude bias.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: March 31, 2020
    Assignee: The General Hospital Corporation
    Inventors: Cornelius Eichner, Kawin Setsompop, Lawrence Wald, Stephen Cauley
  • Patent number: 10595844
    Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: March 24, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Namal Nawana, William C. Horton, William J. Frasier, Cody Cranson, Max Reinhardt, Mark T. Hall, Matthew Parsons, Jennifer DiPietro, Kevin Lee, Michelle LaWare, John P. Griffin, Sean P. Selover, Jonathan Bellas, Douglas Raymond, Nicholas Pavento, Mary L. Fowler, Dennis Chien
  • Patent number: 10602114
    Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see-through display.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: March 24, 2020
    Assignee: OnPoint Medical, Inc.
    Inventor: Carlos Quiles Casas
  • Patent number: 10588587
    Abstract: A system and method for reconstructing a series of images of a subject includes acquiring medical image data from the subject with a medical imaging system and reconstructing a series of images of the subject from the acquired medical image data set. The reconstructing includes enforcing general adherence to a non-patient-specific signal model that describes a dependency of image intensity values on at least one variable that is associated with a physical or physiological property by constraining reconstruction of individual images in the series of images using the non-patient-specific model. The reconstructing also includes preserving information in the series of images that deviate from the non-patient-specific model by controlling a requirement of consistency with the non-patient-specific model.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: March 17, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Alexey A. Samsonov, Julia V. Velikina
  • Patent number: 10594998
    Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see-through display.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: March 17, 2020
    Assignee: OnPoint Medical, Inc.
    Inventor: Carlos Quiles Casas
  • Patent number: 10575755
    Abstract: A computer-implemented technique for calculating a position of a surgical device relative to a patient region imaged by an imaging device is described. One of the surgical device and the imaging device has a predetermined first positional relationship to a marking, and a first camera having a field of view that includes the marking has a predetermined second positional relationship to the other device. The positional relationships may be stored as calibration data. A method realization of the technique comprises the steps of receiving, from the imaging device, intra-operatively taken first image data representative of the imaged patient region, receiving, from the first camera, intra-operatively taken second image data representative of the marking, and intra-operatively calculating, based on the first and second image data and the calibration data, the position of at least a part of the surgical device relative to the imaged patient region.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: March 3, 2020
    Assignee: Stryker European Holdings I, LLC
    Inventors: Jochen Breisacher, Amir Sarvestani
  • Patent number: 10571536
    Abstract: A magnetic resonance imaging (MRI) system includes a split magnet system having a pair of MRI magnet housings separated by gap. A pair of main MRI magnets are disposed within respective MRI magnet housings. A plurality of buttress assemblies are attached to the MRI magnet housings. Some or all of the buttress assemblies are provided with removable connections to the MRI magnet housings. This allows for partial disassembly of the MRI system for improved transport and maneuverability for relocating the MRI system. The MRI system can include a gantry in the gap for supporting a radiation therapy system. Also, the removably buttress assemblies can be used for housing conduits, such as electrical and fluid conduits, between the pair of MRI magnet housings.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: February 25, 2020
    Assignee: ViewRay Technologies, Inc.
    Inventors: James F. Dempsey, John L. Patrick, Shmaryu M. Shvartsman, Gordon D. Demeester
  • Patent number: 10573009
    Abstract: Provided is an in vivo movement tracking apparatus configured to track a portion of interest that moves in vivo, in which accuracy and robustness of tracking are improved. The apparatus is configured to determine an estimated position of ah organ in a biological image based on the past movement of the organ and search for contour points corresponding to a plurality of control points, respectively, representing a contour shape of the organ in a region corresponding to the estimated position, to thereby determine an estimated contour of the organ based on the contour points. The in vivo movement tracking apparatus is configured to determine a position of a portion of interest, which moves in association with the organ, based on the estimated contour with reference to previously acquired sample data regarding a positional relationship between a contour of the organ and the portion of interest.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: February 25, 2020
    Assignees: THE UNIVERSITY OF TOKYO, THE UNIVERSITY OF ELECTRO-COMMUNICATIONS, PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY
    Inventors: Norihiro Koizumi, Atsushi Kayasuga, Kyohei Tomita, Izumu Hosoi, Yu Nishiyama, Hiroyuki Tsukihara, Hideyo Miyazaki, Hiroyuki Fukuda, Kazushi Numata, Kiyoshi Yoshinaka, Takashi Azuma, Naohiko Sugita, Yukio Homma, Yoichiro Matsumoto, Mamoru Mitsuishi
  • Patent number: 10571540
    Abstract: MRI interference with a concurrently operated system may be reduced or corrected by subtracting the MRI interference from signals measured using the concurrently operated system.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: February 25, 2020
    Assignee: INSIGHTEC, LTD.
    Inventor: Benny Assif
  • Patent number: 10559095
    Abstract: There is provided with an image processing apparatus. A determination unit determines color information of an object present in an object image from a virtual viewpoint. The color information of the object is determined by combining color information of the object in a captured image obtained by one or more image capturing apparatus selected based on position and orientation information of the virtual viewpoint, position and orientation information of the image capturing apparatuses, and position information of the object, by using a weight corresponding to an image capturing direction of the one or more image capturing apparatus and a position of the object in a field of view of the one or more image capturing apparatus.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: February 11, 2020
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Kazuhiro Yoshimura, Tatsuro Koizumi
  • Patent number: 10551456
    Abstract: In a method, apparatus and medical imaging system to generate image data based on magnetic resonance (MR) thermometry data, planning data of a region of an examination subject that is to be depicted thermometrically are provided to a processor. Through the processor, segmentation data based on the planning data are generated MR thermometry data are provided to the processor, which generates image data on the basis of the MR thermometry data, using the segmentation data.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: February 4, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Joerg Roland, Eva Rothgang, Michael Suehling
  • Patent number: 10548678
    Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: February 4, 2020
    Assignee: MONTERIS MEDICAL CORPORATION
    Inventors: Richard Tyc, Salman Qureshi, Mark Andrew Grant, Luis Filipe Silva Fernandes, Daniel Prazeres Carreira, John Schellhorn
  • Patent number: 10551542
    Abstract: According to one implementation an assembly is provided that facilitates a coupling of one or more light diffusing optical fibers to one or more light emitting diodes. According to one implementation the assembly includes a light emitting diode positioned inside a cavity of a frame that is equipped with means to directly or indirectly electrically couple the anode and cathode of the light emitting diode to a printed circuit board. A proximal end portion of the light diffusing optical fiber is supported inside a through opening of a lid positioned over a front side of the frame. The light diffusing optical fiber includes a core that is surround by a cladding. According to some implementations the proximal end of the light diffusing optical fiber is butt-coupled to the light emitting diode with there being no gap between the proximal end of the fiber and the light emitting side of the light emitting diode.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: February 4, 2020
    Assignee: Corning Incorporated
    Inventors: Qing Tan, Mario Paniccia, Tim L. Kitchen
  • Patent number: 10548506
    Abstract: Systems and methods for manufacturing and using magnetic resonance (“MR”) visible labels, markers, or assemblies to encode information unique to the subject or object being imaged by a magnetic resonance imaging (“MRI”) system are provided. The use of such MR-visible labels, markers, or assemblies enables unique information associated with the subject or object being imaged to be encoded into the images of the subject or object. This information can be used to anonymize protected health information (“PHI”); to provide detailed information about a surgical simulation device, quality assurance phantom, or the like; to provide spatial orientation and registration information; or so on.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: February 4, 2020
    Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.
    Inventors: Gregory A. Whitton, Timotheus Gmeiner, Fergal Kerins
  • Patent number: 10536686
    Abstract: An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: January 14, 2020
    Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.
    Inventors: William La, Siu Wai Jacky Mak
  • Patent number: 10517490
    Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: December 31, 2019
    Assignees: Siemens Healthcare GmbH, Northshore University Healthsystem
    Inventors: Shivraman Giri, Robert R. Edelman, Ioannis Koktzoglou, Himanshu Bhat
  • Patent number: 10511822
    Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see through display.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: December 17, 2019
    Assignee: OnPoint Medical, Inc.
    Inventor: Carlos Quiles Casas
  • Patent number: 10506991
    Abstract: A method includes, receiving (i) a set of two-dimensional (2D) slices of a segmented three-dimensional (3D) anatomical image of an organ of a patient, and (ii) position signals that are indicative of respective position and orientation of a distal tip of a medical tool in the organ. An optical axis of the medical tool is estimated based on the position signals. A slice that is: (i) oriented at a predefined angle relative to the optical axis, and (ii) includes the position of the distal tip, is selected from among the slices. The selected slice is displayed to a user, together with a marker indicative of the position of the distal tip.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: December 17, 2019
    Assignee: Biosense Webster (Israel) Ltd.
    Inventor: Assaf Govari
  • Patent number: 10492709
    Abstract: Body-mountable devices are provided to detect the presence or status of an analyte in subsurface vasculature of a body by detecting fluorescent reporters that are bound to instances of the analyte in the subsurface vasculature. Such devices further operate to exert an attractive magnetic force on magnetic nanoparticle-containing probes that are configured to bind to the analyte, thus concentrating the analyte proximate the devices by magnetically exerting attractive forces on such probes that are bound to instances of the analyte. The analyte can be an extracellular vesicle that is characteristic of a cancer, and a body-mountable device as described herein could be used to detect such extracellular vesicles in a portion of subsurface vasculature such that a presence or status of a tumor could be determined based on an amount, presence, or other detected property of the extracellular vesicle.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: December 3, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Mark Audeh, Joshua Simon Klein, Anthony M Giannetti, Stephen Morton, James Michael Higbie
  • Patent number: 10495706
    Abstract: Combined MRI and radiotherapy installations require complex Faraday cage structure that encloses the room, the MRI magnets, and the patient volume, but excludes the linear accelerator path and its supply cabling. A problem with this is that the MRI magnets tend to vibrate when in use, and if physically connected to a rigid structure then the vibrations will be passed to that structure also. To alleviate this, we propose that the Faraday cage be made of a mix of prefabricated conductive sections and flexible sections of a conductive sheet. The flexible conductive sheet can be copper or aluminium, in the form of a foil or mesh.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: December 3, 2019
    Assignee: Elekta Limited
    Inventors: Jurgen Michael Mikeska, Andreas Michael Hainke
  • Patent number: 10495707
    Abstract: In beta emission imaging, magnetic lensing allows a lower resolution detector to detect the spatial distribution of emissions at a higher resolution. The sample is placed in a magnetic field with field lines at a given density, and the detector is placed away from the sample where the magnet field lines diverge, resulting in a lesser density. Since the beta emissions travel along the field lines, the divergence of the field lines from the sample to the detector result in lensing or magnification. Using positron attenuation tomography to detect annihilation in the detector allows for correction due to self-absorption by the sample. The correction and lensing are used together or may be used independently.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: December 3, 2019
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventor: Charles C. Watson
  • Patent number: 10485992
    Abstract: It is an object of the invention to provide for a system, method and computer program product enabling monitoring of effects of intrafraction motion during the radio therapy treatment. According to a first aspect of the invention this object is achieved by an ultrasound guided radiotherapy system, comprising a radiotherapy system configured for providing a radiation treatment by means of a radiation beam to a treatment target. The ultrasound guided radiotherapy system further comprises an ultrasound imaging system configured for acquiring a 3D online image of the treatment target and/or an organ at risk during the radiation treatment.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: November 26, 2019
    Inventors: Harald Sepp Heese, Torbjorn Vik, Heinrich Schulz, Christian Buerger, Jochen Peters
  • Patent number: 10481114
    Abstract: A core holder for a reservoir rock core sample for MR or MRI measurement including a casing and a chamber internal to the core holder, an inlet and an outlet in the core holder for circulating a confining fluid in the chamber, a sample housing in the chamber for containing the core sample, the sample housing including an inlet and an outlet in the sample holder for circulating fluid to and from the sample, and a membrane for isolating the sample from fluid contact with the confining fluid but permitting fluid pressure to be exerted on the sample when the confining fluid is pressurized, the space in the chamber not occupied by the sample housing defining a void space, an RF probe in the void space and at least partially surrounding the sample housing, whereby confining fluid introduced into the chamber circulates in the void space around the RF probe.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: November 19, 2019
    Assignee: University of New Brunswick
    Inventors: Mojtaba Shakerian, Bruce J. Balcom
  • Patent number: 10475192
    Abstract: During a focused-ultrasound or other non-invasive treatment procedure, the motion of the treatment target or other object(s) of interest can be tracked in real time based on (i) the comparison of treatment images against a reference library of images that have been acquired prior to treatment for the anticipated range of motion and have been processed to identify the location of the target or other object(s) therein and (ii) complementary information associated with the stage of the target motion during treatment.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 12, 2019
    Assignee: INSIGHTEC, LTD.
    Inventor: Yoav Levy
  • Patent number: 10463880
    Abstract: An applicator device (100, 200, 300) for use in interventional brachytherapy, wherein the applicator device (100, 200, 300) is configured to be inserted in, or near a region of interest within a living body, and the applicator device is defining a lumen (101, 201, 301) for receiving a radiation source (103, 203, 303), characterized in that the applicator device (100, 200, 300) comprises one or more sensor elements (102, 202, 302) each configured to generate an output signal indicative of whether or not the radiation source (103, 203, 303) is at a predetermined position in the lumen (101, 201, 301).
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: November 5, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Guillaume Leopold Theodorus Frederik Hautvast, Dirk Binnekamp
  • Patent number: 10463855
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: November 5, 2019
    Assignees: NEUROELECTRICS BARCELONA S.L., BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
  • Patent number: 10456594
    Abstract: A brachytherapy method and apparatus include implanting an applicator having at least one radiation source or seed receiving channel (62) into soft tissue adjacent a target region (40) to be irradiated. A high resolution planning image (64) of the target region including the applicator is generated, wherein the high resolution planning image is used for determining a three-dimensional treatment plan (66). A position of the applicator is tracked relative to the target region (40) and the treatment plan (66). Tracking the position includes measuring, via shape-sensing, a location and shape of the at least one radiation source or seed receiving channel (62).
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: October 29, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Laurent Verard, Luis Felipe Gutierrez, Dirk Binnekamp
  • Patent number: 10448003
    Abstract: An intraoperative, marker-less visualization system and method for visualizing three-dimensional surface structures and depth structures of a patient during an intervention. A C-arm carries a C-arm projection module and a camera, and visualization spectacles include an HMD (head-mounted device) projection module and a camera. The projection modules serve for projecting structured light. A processor computes a combined image data set in order to project the latter onto spectacle lenses of the visualization spectacles.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: October 15, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventor: Alexander Grafenberg
  • Patent number: 10433929
    Abstract: A method for registering a catheter navigation system to a three-dimensional image generally includes obtaining a three-dimensional image including position information for a plurality of surface points on a part of a patient's body, using a catheter navigation system to place a tool at a location on the surface of the patient's body, measuring position information for the surface location, identifying a corresponding location on the image, associating position information for the surface location and the location identified on the image as a fiducial pair, and using at least one fiducial pair to generate a mapping function. The mapping function transforms points within the coordinate system of the catheter navigation to the coordinate system of the three-dimensional image such that, for each fiducial pair, the mapping error is about zero. Suitable warping algorithms include thin plate splines, mean value coordinates, and radial basis function networks.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: October 8, 2019
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Eric S. Olson, Eric J. Voth, Jeffrey A. Schweitzer
  • Patent number: 10426374
    Abstract: The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: October 1, 2019
    Assignee: The Regents of the University of California
    Inventors: Krystof S. Bankiewicz, Kathryn H. Rosenbluth, Adrian P Kells
  • Patent number: 10413363
    Abstract: A method for enhancing a surgical procedure includes providing a three-dimensional model of a patient's organ of a patient based on pre-operative image data of the patient's organ; identifying positional data corresponding to a first position of at least one target treatment anatomy of the patient relative to a second position of an ancillary target anatomy of the patient based on an analysis of the three-dimensional model of the patient's organ of the patient; selecting a puncture location based on the identified positional data; and displaying, by an augmented reality device, a virtual organ object via an augmented reality display system overlaying a real-world environment, the virtual organ object corresponding to the three-dimensional model and visually indicating the selected puncture location.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: September 17, 2019
    Assignee: Medtronic, Inc.
    Inventors: Mina S. Fahim, Peter N. Braido, Ross D. Hinrichsen
  • Patent number: 10406384
    Abstract: The invention provides for medical instrument (200, 400) comprising a magnetic resonance imaging system (202) and a high intensity focused ultrasound system (222). A processor (246) controls the medical instrument. Instructions cause the processor to control (100) the magnetic resonance imaging system to acquire the magnetic resonance data using a pulse sequence (254). The pulse sequence comprises an acoustic radiation force imaging pulse sequence (500, 600). The acoustic radiation force imaging pulse sequence comprises an excitation pulse (512) and a multi-dimensional gradient pulse (514) applied during the radio frequency excitation pulse for selectively exciting a region of interest (239) encompassing a target zone and at least a portion of the beam axis.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: September 10, 2019
    Assignee: Profound Medical Inc.
    Inventor: Max Oskar Köhler
  • Patent number: 10398513
    Abstract: Presented herein are methods, systems, devices, and computer-readable media for image management in image-guided medical procedures. Some embodiments herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound transducers or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets and allow the operator to control the presentation of regions of interest. Additionally, some embodiments provide for quick calibration of surgical instruments or attachments for surgical instruments.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: September 3, 2019
    Assignee: InnerOptic Technology, Inc.
    Inventors: Sharif Razzaque, Andrei State, Caroline Green, Brian Heaney
  • Patent number: 10402969
    Abstract: Systems and methods are provided for a visualization of a multi-modal medical image for diagnostic medical imaging. The systems and methods receive first and second image data sets of an anatomical structure of interest, register the first and second image data sets to a geometrical model of the anatomical structure of interest to form a registered image. The geometrical model includes a location of an anatomical marker. The systems and methods further display the registered image.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: September 3, 2019
    Assignee: General Electric Company
    Inventors: Eigil Samset, Olivier Gerard, Stian Langeland