Magnetic Resonance Imaging Or Spectroscopy Patents (Class 600/410)
  • Patent number: 10326317
    Abstract: A method for foreign object detection for an induction charging device is described, including an oscillator circuit, in particular, for a hand-held power tool, a resonance frequency and an associated actual quality of the oscillator circuit being detected and the actual quality is subsequently compared to a setpoint quality as a function of the resonance frequency and a decision is made about the presence of a foreign object based on a defined setpoint quality range. The method provides that an upper limit and/or a lower limit of the setpoint quality range and the profile of the actual quality are adapted to one another. Also described is an induction charging device including an oscillator circuit and a control and regulating unit for carrying out the method.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: June 18, 2019
    Assignee: Robert Bosch GmbH
    Inventors: Dragan Krupezevic, Martin Gonda
  • Patent number: 10324153
    Abstract: A system and method for calculating a flip angle schedule is provided. The technique includes selecting an initial condition, providing a function for calculating flip angles, calculating flip angles, assessing the flip angles, and repeating the calculation of the flip angles by adjusting the function until a desired flip angle schedule is obtained.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: June 18, 2019
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Guobin Li, Chaohong Wang
  • Patent number: 10319147
    Abstract: Performing volume rendering in a virtual reality environment by applying an adapted Monte Carlo integration, grid accelerator-based view ray tracing, image filtering, and user-movement detected adapted frame compensation.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: June 11, 2019
    Assignee: ARIVIS AG
    Inventors: Falko Löffler, Baul Bönisch, Christian Götze, Andreas Suchanek
  • Patent number: 10319102
    Abstract: An image processing apparatus according an exemplary embodiment of the present invention estimates for a plurality of positions in a target image an estimated value of an error in registration for acquiring a third three-dimensional image by deforming at least one of a first three-dimensional image of a subject and a second three-dimensional image, one of the three-dimensional images being the target image, designates a cross section in the target image, acquires a statistical value of the error in the designated cross section based on the estimated value estimated for a plurality of positions in the cross section, and displays the statistical value.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: June 11, 2019
    Assignee: Canon Kabushiki Kaisha
    Inventors: Takaaki Endo, Kiyohide Satoh, Yasufumi Asao, Yohei Hashizume
  • Patent number: 10307076
    Abstract: Systems and methods are provided for detecting collagen within tissue using magnetic resonance imaging. In some embodiments, pulse sequences are employed to measure signals at multiple TE values including ultra-short echo times, and the TE dependence of the measured signal is fitted to a mathematical function including at least two decay terms, where the first (initial) decay term is modulated and is associated with the presence of collagen. In another example embodiment, spectroscopy or spectroscopic imaging is employed to measure the free induction decay within at least one region of interest, and the time-dependence of the measured signal is fitted to a mathematical function including at least two decay terms, where the first decay term is modulated and is associated with the presence of collagen. In some embodiments, the methods described herein may be employed for the detection and/or assessment of myocardial fibrosis.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: June 4, 2019
    Assignee: Sunnybrook Research Institute
    Inventors: Adrienne Grace Siu, Graham A. Wright
  • Patent number: 10311978
    Abstract: A method and system for patient-specific planning of cardiac therapy, such as cardiac resynchronization therapy (CRT), based on preoperative clinical data and medical images, such as ECG data, magnetic resonance imaging (MRI) data, and ultrasound data, is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image data of a patient. A patient-specific computational heart model, which comprises cardiac electrophysiology, biomechanics and hemodynamics, is generated based on the patient-specific anatomical model of the left and right ventricles and clinical data. Simulations of cardiac therapies, such as CRT at one or more anatomical locations are performed using the patient-specific computational heart model. Changes in clinical cardiac parameters are then computed from the patient-specific model, constituting predictors of therapy outcome useful for therapy planning and optimization.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: June 4, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Tommaso Mansi, Bogdan Georgescu, Xudong Zheng, Ali Kamen, Dorin Comaniciu
  • Patent number: 10302728
    Abstract: A magnetic resonance imaging apparatus includes a signal transceiver, and a sequence controller configured to control the signal transceiver to apply an RF pulse and a gradient magnetic field to a first portion of an object, wait for blood to flow from the first portion of the object to which the RF pulse and the gradient magnetic field are applied, to a second portion of the object, and apply the RF pulse and the gradient magnetic field to the second portion of the object to which the blood flows, using a 3D balanced steady-state free precession (bSSFP), and subsample first magnetic resonance data from the second portion of the object to which the RF pulse and the gradient magnetic field are applied. The apparatus further includes an image processor configured to generate label image data based on the first magnetic resonance data.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: May 28, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jin-young Hwang, Joon-soo Kim
  • Patent number: 10299669
    Abstract: A method for accessing the interior of a joint, wherein the joint comprises tissue which defines a boundary of the joint, the tissue comprising an interior surface facing toward the interior of the joint and an exterior surface facing away from the interior of the joint, the method comprising: providing a light-emitting needle assembly comprising a hollow needle having a light source at the distal end thereof; and observing the interior surface of the tissue from the interior of the joint as the needle approaches the exterior surface of the tissue.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: May 28, 2019
    Assignee: Pivot Medical, Inc.
    Inventor: Andrew J. Hamel
  • Patent number: 10302726
    Abstract: This invention provides an image processing method and apparatus for reconstructing an image of a site of a subject. The image processing method comprises: generating a first estimated phase of each shot of multiple shots of the site by sensitivity encoding based on shot data of the corresponding shot obtained for the site; reconstructing a first multiplexed sensitivity encoded image based on the first estimated phase of each shot and shot data of each shot; generating a second estimated phase of each shot of the multiple shots by regularized sensitivity encoding using the first multiplexed sensitivity encoded image; and reconstructing a second multiplexed sensitivity encoded image based on the second estimated phase of each shot and shot data of each shot. In this way, the quality of the finally reconstructed image in magnetic resonance imaging is further improved.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: May 28, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Feng Huang, Hua Guo, Zhe Zhang, Bi Da Bd Zhang
  • Patent number: 10302714
    Abstract: Systems and methods are provided for automatically designing RF pulses using a reinforcement machine-learnt classifier. Data representing an object and a selected outcome is accessed. A reinforcement learnt method identifies the RF pulse sequence that generates a result within a predefined value of the selected outcome. An MRI scanner images the object using the RF pulse sequence.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: May 28, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Xiao Chen, Mariappan S. Nadar, Benjamin L. Odry, Boris Mailhe
  • Patent number: 10303986
    Abstract: A decision-support system and computer implemented method automatically measures the midline shift in a patient's brain using Computed Tomography (CT) images. The decision-support system and computer implemented method applies machine learning methods to features extracted from multiple sources, including midline shift, blood amount, texture pattern and other injury data, to provide a physician an estimate of intracranial pressure (ICP) levels. A hierarchical segmentation method, based on Gaussian Mixture Model (GMM), is used. In this approach, first an Magnetic Resonance Image (MRI) ventricle template, as prior knowledge, is used to estimate the region for each ventricle. Then, by matching the ventricle shape in CT images to the MRI ventricle template set, the corresponding MRI slice is selected. From the shape matching result, the feature points for midline estimation in CT slices, such as the center edge points of the lateral ventricles, are detected.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: May 28, 2019
    Inventors: Kayvan Najarian, Wenan Chen, Kevin R. Ward
  • Patent number: 10292670
    Abstract: A system and method for simulating energy transport between particles and an object in radiotherapy is provided. A three-dimensional representation, having a plurality of voxels, is generated for a portion of a patient to be treated. A material index for each of the plurality of voxels is determined. The material index has an identifier for a first boundary material corresponding to a voxel and a percentage of the voxel associated with a second boundary material. The method further comprises simulating energy transport between a particle and the object by calculating an amount of energy deposited by a particle within the patient based on the material indices of the voxels and a list of boundary materials.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: May 21, 2019
    Assignee: Elekta Ltd.
    Inventor: Sami Hissoiny
  • Patent number: 10295487
    Abstract: Devices and methods are provided for measuring temperatures and pHs of a sample in situ using NMR spectroscopy, and for sealing one or more ends of a capillary tube after a reference material has been added to the capillary tube, which is used in an in situ NMR temperature measurement device. A method for measuring a pH of a sample in situ using NMR spectroscopy includes providing an in situ NMR pH measurement device. This device includes a sample housing member configured to house a target sample, at least one pH sensor configured to exhibit an NMR spectral change due to a change in pH value of the target sample, and a pH sensor containment member configured to house the at least one pH sensor. The target sample is added to the sample housing member. NMR spectra are obtained to then determine the pH of the target sample.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: May 21, 2019
    Assignee: The Curators of the University of Missouri
    Inventors: Ming Huang, Lingyu Chi, Rex E. Gerald, II, Jie Huang, Annalise R. Pfaff, Klaus Woelk
  • Patent number: 10295640
    Abstract: In a method and magnetic resonance apparatus for generating motion-corrected magnetic resonance measurement data, reference data and measurement data are acquired from multiple sub-regions of an examination region of a subject, and first and second items of movement information are respectively generated for the respective sub-regions, and motion-corrected data for the respective sub-regions is generated by transforming k-space data using the first and second items of movement information.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: May 21, 2019
    Assignee: Siemens Healthcare GmbH
    Inventor: Thomas Beck
  • Patent number: 10285657
    Abstract: A diagnosis support device, which is suitable for comparing different diseases, is provided, along with others. In the diagnosis support device, the input of an MRI brain image of a subject is received, and a shrinkage score, which represents the degree of shrinkage of the brain, is calculated based on the MRI brain image. Subsequently, sites to be compared in the brain are identified. Then, a degree of shrinkage, which represents the degree of shrinkage of each of the identified sites, and a shrinkage ratio, which is the ratio between the degrees of shrinkage of the sites, are calculated, and then compared and displayed.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: May 14, 2019
    Assignee: DAI NIPPON PRINTING CO., LTD.
    Inventors: Tetsutaro Ono, Tomoaki Goto, Hiroshi Matsuda
  • Patent number: 10285639
    Abstract: Disclosed herein are methods, non-transitory computer-readable medium, and systems for determining an estimate of fat within a volume of a subject by determining a parameter ? from the signal intensities of at least three echo signals emitted from a region of the volume of a subject imaged by a magnetic resonance image scanner in response to an applied RF pulse, wherein the three echo signals are taken at a first opposing-phase echo time, a second opposing-phase echo time and an in-phase echo time; and determining a fat volume fraction, f, from the parameter ?.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: May 14, 2019
    Assignee: Resonance Health Analysis Services Pty Ltd
    Inventors: Timothy Guy St Pierre, Sander Jonathan Bangma, Michael J. House
  • Patent number: 10288703
    Abstract: A method for accelerating magnetic resonance imaging is proposed. In 3D MRI, the method utilizes two sub-echo-trains in each repetition time for the simultaneous acquisition of two contrasts. The first sub-echo-train is a turbo spin echo train and the second sub-echo-train is a gradient echo train. The method acquires two different contrasts simultaneously in a single acquisition, for example one water image plus one fat image, or one turbo spin echo image plus one susceptibility weighted image.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: May 14, 2019
    Assignee: Albert-Ludwigs-Universitaet Freiburg
    Inventors: Guobin Li, Maxim Zaitsev, Juergen Hennig
  • Patent number: 10275875
    Abstract: A method for automatically and dynamically optimizing image acquisition parameters/commands of an imaging procedure performed by a medical imaging apparatus in order to mitigate or cancel dynamic effects perturbing the image acquisition process of an object to be imaged by the medical imaging apparatus. The method includes connecting a dynamic correction module (DCM) to the medical imaging apparatus, automatically acquiring by the DCM image acquisition parameters/commands and data about dynamic changes or effects, and automatically determining in real time, by the DCM, at least one new image acquisition parameter/command from the image acquisition parameters/commands defined in the imaging control system and the dynamic change data, while the image acquisition parameter/command defined in the imaging control system remains unchanged. The method further includes automatically providing, by the DCM, the new image acquisition parameter/command to the hardware control system.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: April 30, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Himanshu Bhat, Thorsten Feiweier, Tobias Kober, Carsten Prinz, Daniel Nico Splitthoff, Stephan Stoecker
  • Patent number: 10261145
    Abstract: A system and method for magnetic resonance imaging (MRI) and static field (B0) shimming. A coil system includes a conductive loop configured to be arranged proximate to a region of interest (ROI). The coil system also includes an alternating current (AC) circuit electrically connecting the conductive loop to an AC electrical connection configured to be coupled to an MRI system to communicate medical imaging signals received by the conductive loop from the ROI during a medical imaging procedure to the MRI system. The coil system further includes a direct current (DC) circuit electrically connecting the conductive loop to a DC electrical connection configured to be coupled to a DC power source and a plurality of circuit components configured to block DC signals from reaching the AC electrical connection in order to produce a spatially varying static magnetic field for shimming inhomogenieties of the static field.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: April 16, 2019
    Assignee: The General Hospital Corporation
    Inventors: Lawrence Wald, Jason Stockmann
  • Patent number: 10247804
    Abstract: A method of operating a respiratory-guided magnetic resonance imaging system (10) with regard to triggering of magnetic resonance image acquisition, the magnetic resonance imaging system (10) being connectable to a respiration monitoring device (46) which is configured to provide an output signal (48) whose level represents a respiration state of the subject of interest (20), the method comprising a step (56) of generating an interleaved acquisition scheme for acquiring magnetic resonance images, a step (60) of adapting, in case of an occurrence of an irregularity in the breathing of the subject of interest (20) in the output signal (48) obtained by the respiration monitoring device (46) in the course of executing magnetic resonance image acquisition, at least one parameter of the interleaved acquisition scheme, wherein the at least one adapted parameter is at least one of a next respiration state of the subject of interest (20) to trigger on for acquiring at least one magnetic resonance image, a radio freque
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: April 2, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Tim Nielsen, Sascha Krueger
  • Patent number: 10241182
    Abstract: A magnetic resonance imaging system (1) includes at least one processor (28) configured to receive (48) diffusion weighted imaging data based on a diffusion weighted imaging sequence with magnetic gradient fields applied in different directions and with different b-values. The at least one processor (28) is further configured to detect (50) motion corrupted data present in the received imaging data based on a comparison of data redundant in the received data, and substitute (52) alternative data for detected motion corrupted data.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: March 26, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Christian Stehning, Thomas Perkins, Julien Senegas, Jochen Keupp
  • Patent number: 10215828
    Abstract: A magnetic resonance imaging apparatus includes a sequence controller. The sequence controller is configured to apply MT (Magnetization Transfer) pulses having a frequency different from a resonance frequency of free water protons and then acquires magnetic resonance signals of an object to be imaged. The sequence controller acquires the magnetic resonance signals for each of multiple frequencies while changing the frequency of MT pulses within a frequency band based on a T2 relaxation time of restricted protons contained in the object to be imaged.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: February 26, 2019
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Mitsue Miyazaki, Cheng Ouyang, Xiangzhi Zhou
  • Patent number: 10204412
    Abstract: A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry. The processing circuitry generates an image based on a magnetic resonance signal from a subject. The processing circuitry generates a susceptibility image representing magnetic susceptibility of the subject from a phase component contained in a plurality of pixels in the image. The processing circuitry generates an artifact component of the susceptibility image based on a frequency signal obtained by frequency transform of the susceptibility image. The processing circuitry generates an artifact component-removed susceptibility image by removing the artifact component from a susceptibility image generated based on the magnetic resonance signal.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 12, 2019
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Taichiro Shiodera, Takamasa Sugiura, Tomoyuki Takeguchi, Masao Yui, Naotaka Sakashita
  • Patent number: 10194830
    Abstract: A method of monitoring a position of a catheter tip relative to a target tissue. The method includes steps of identifying a wall structure in the target tissue; guiding a catheter towards the wall structure; monitoring a location of the catheter; directing a navigator beam towards the wall structure; aligning the navigator beam with the location of the catheter; monitoring a position of the wall structure using the navigator beam; and determining the position of the wall structure relative to the location of the catheter.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: February 5, 2019
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Ashvin Kurian George, Evgueni G. Kholmovski, Nassir F. Marrouche
  • Patent number: 10191131
    Abstract: In a method for operating a medical imaging apparatus having subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes, for a series of states of physiological processes that occur during the scan sequence. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions per observed state, that optimize the functional subsequences of the scan sequence locally.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 29, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Peter Speier
  • Patent number: 10192293
    Abstract: In an example, a method and apparatus for obtaining an image mask is provided. After a magnitude image and a phase image of a to-be-processed image is obtained, magnitude coherent data of each pixel point in the magnitude image and phase coherent data of each pixel point in the phase image may be calculated. Then, a binarization threshold processing may be performed on the magnitude coherent data of each pixel point in the magnitude image to obtain a magnitude image mask. A binarization threshold processing may be performed on the phase coherent data of each pixel point in the phase image to obtain a phase image mask. In this way, an image mask of the to-be-processed image may be obtained by using the magnitude image mask and the phase image mask.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: January 29, 2019
    Assignee: Shenyang Neusoft Medical Systems Co., Ltd.
    Inventors: Haoda Ding, Hongyu Guo, Hongbing Hu
  • Patent number: 10191126
    Abstract: Systems and methods for producing an image of the electrical properties of an object using magnetic resonance imaging (“MRI”) are provided. The electrical properties are determined based on estimated gradient values of the electrical properties of the object. For instance, electrical property maps are reconstructed using a spatial integration on gradient values that are estimated from the magnitude and relative phase values derived from measurements of multiple transmit and receive B1fields. Specific absorption rate (“SAR”) maps can also be produced based on the estimated electrical properties.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: January 29, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Bin He, Jiaen Liu, Xiaotong Zhang, Pierre-Francois Van de Moortele
  • Patent number: 10191132
    Abstract: An MRI method includes performing a first image acquisition module of a pulse sequence to acquire a first MR data from slices disposed at different locations in a region of interest (ROI) of an object; performing a second image acquisition module of the pulse sequence, to acquire a second MR data from the slices disposed at the different locations of the ROI, with a T2 preparation time different than that of the first image acquisition module; and generating a T2 map based on the acquired first MR data and the acquired second MR data.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: January 29, 2019
    Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Tamer Basha, Reza Nezafat
  • Patent number: 10186073
    Abstract: Thresholds b1, b2, b3, and b4 are set in the luminance of a raw image. In an image 84a of the lowermost layer, the region in which the luminance is equal to or higher than b1 is left. In an image 84b over it, the region in which the luminance is equal to or higher than b2 is left. In an image 84c over it, the region in which the luminance is equal to or higher than b3 is left. In an image 84d of the uppermost layer, the region in which the luminance is equal to or higher than b4 is left. In each of these images, the alpha value of the other region is set to 0. The images are integrated with the color information of the raw image to generate final slice images. A display image is generated by stacking the generated slice images sequentially from the lowermost layer at predetermined intervals and performing drawing according to the point of sight.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: January 22, 2019
    Assignee: SONY INTERACTIVE ENTERTAINMENT INC.
    Inventor: Masaaki Oka
  • Patent number: 10175326
    Abstract: Systems and methods for pointwise encoding time reduction with radial acquisition (“PETRA”) magnetic resonance imaging (“MRI”) using a gradient modulation scheme to enable higher readout bandwidth while keeping the missing samples of the central region of k-space small are provided. This acquisition scheme allows independent selection of the excitation and readout bandwidths, which allows a higher readout bandwidth while keeping the required number of missing central k-space samples low. This flexibility in selecting the excitation and readout bandwidth settings can mitigate the peak radio frequency power and specific absorption rate limitations on flip angle in traditional PETRA imaging schemes.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: January 8, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Naoharu Kobayashi, Michael Garwood
  • Patent number: 10176568
    Abstract: A tomography apparatus includes an image processor configured to obtain a first image, which is a partial image of an object, by using data obtained from a first angle section corresponding to a first point, and to obtain a second image, which is a partial image of the object, by using data obtained from a second angle section corresponding to a second point subsequent to the first point; and a controller configured to obtain first information representing a brightness change, to obtain second information representing a rate of change in a Hounsfield unit (HU) value between the first point and the second point based on the first information, and to determine a tomography start point of the object based on the second information.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: January 8, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Ji-young Jung, Jong-hyon Yi, Min-kyu Sun
  • Patent number: 10176587
    Abstract: The present invention provides an apparatus for displaying a two-dimensional cross-sectional image of an arbitrary base plane which matches to the subject's head without creating extra labor to the operator even when the subject's head is asymmetrical. The apparatus is connected to a display unit for displaying a cross-sectional image of a head. The apparatus comprising: a conversion parameter obtaining unit for obtaining a conversion parameter indicating a difference in shape between a standard head and a subject's head based on a volume data; a subject base plane generating unit for generating an anatomical base plane of the subject's head based on the conversion parameter and an anatomical base plane of the standard head; and a cross-sectional reconstruction unit for generating a cross-sectional image of the anatomical base plane of the subject's head based on the volume data of the subject's head and displaying said cross-sectional image on the display unit.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: January 8, 2019
    Assignee: Akita Prefectural Hospital Organization
    Inventors: Noriyuki Takahashi, Tomomi Ohmura
  • Patent number: 10168407
    Abstract: In a method for operating a medical imaging apparatus having multiple subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions that optimize the functional subsequences of the scan sequence locally, at least with regard to a sub-region of the respective effective volumes.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: January 1, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Peter Speier
  • Patent number: 10168405
    Abstract: Provided are a method and apparatus for processing a magnetic resonance (MR) image of an object including first and second materials on a magnetic resonance imaging (MRI) apparatus by using multi-parameter mapping including applying to the object a plurality of radio frequency (RF) pulses separated by a first repetition time and a second repetition time, the first repetition time and the second repetition time being determined based on the first material and the second material; undersampling first MR signals corresponding to the first material and second MR signals corresponding to the second material in a K-space; and performing matching between the undersampled first and the undersampled second MR signals and a signal model for the multi-parameter mapping to determine attribute values corresponding to the first and the second materials at at least one point in an MR image of the object.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: January 1, 2019
    Assignees: SAMSUNG ELECTRONICS CO., LTD., INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Lae-hoon Kang, Dong-hyun Kim, Min-oh Kim, Dong-yeob Han, Do-sik Hwang, Yong-sup Park, Jong-buhm Park, Jae-sung Lee
  • Patent number: 10168406
    Abstract: In order to provide an effective optimization of a magnetic resonance sequence, particularly with regard to optimizing the slew rates of gradient switching sequences of the magnetic resonance sequence, in a method for optimizing a magnetic resonance sequence of a magnetic resonance apparatus, wherein the magnetic resonance sequence includes multiple pre-set gradient switching sequences with multiple pre-set slew rates, the multiple pre-set slew rates are provided to a computer wherein the multiple pre-set slew rates are evaluated. At least one optimization measure for the magnetic resonance sequence is defined based on the evaluation of the multiple pre-set slew rates. The magnetic resonance sequence is optimized based on the at least one pre-set optimization measure, wherein the optimized magnetic resonance sequence has multiple optimized gradient switching sequences with multiple optimized slew rates, and the multiple optimized slew rates being optimized in relation to the multiple pre-set slew rates.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: January 1, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Dominik Paul, Joerg Roland
  • Patent number: 10161870
    Abstract: An apparatus for detecting a material within a sample includes a light emitting unit for directing at least one light beam through the sample. A plurality of units receive the light beam that has passed through the sample and performs a spectroscopic analysis of the sample based on the received light beam. Each of the plurality of units analyze a different parameter with respect to the sample a provide a separate output signal with respect to the analysis. A processor detects the material with respect each of the provided separate output signals.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: December 25, 2018
    Assignee: NXGEN PARTNERS IP, LLC
    Inventor: Solyman Ashrafi
  • Patent number: 10162031
    Abstract: The present disclosure provides systems and methods which may assist in evaluating liver fibrosis/inflammation in the presence of elevated iron using magnetic resonance relaxometry. In a non-limiting embodiment, the systems and methods include: obtaining a measurement of relaxometry data of a subject's liver for extracellular fluid, preferably using a magnetic resonance imaging (MRI) device; determining an iron content for the liver; simulating a measurement of the subject's liver for extracellular fluid for the determined iron content; comparing the measurement of the subject's liver for extracellular fluid to the simulated measurement of the subject's liver for extracellular fluid; and determining from said comparison a value of extracellular fluid in the subject's liver based on a normal iron content for the liver.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 25, 2018
    Assignee: ISIS INNOVATION LIMITED
    Inventors: Elizabeth Tunnicliffee, Matthew Robson, Rajarshi Banerjee
  • Patent number: 10163204
    Abstract: A method for enhancing a three-dimensional (3D) reconstruction of an object comprises obtaining a signal indicative of a static 3D reconstruction of an object disposed in a tracking space, co-registering the 3D reconstruction to the 3D tracking space, collecting enhancement data from a tracked tool disposed in the 3D tracking space, and adding real-time features of the object to the static 3D reconstruction using the enhancement data. A system for enhancing data obtained by a medical system includes an electronic control unit configured to receive a first signal for a static 3D reconstruction of an organ, co-register the static 3D reconstruction to a 3D tracking space for a tracked tool, receive a second signal for enhancement data generated by the tracked tool operating within a region of interest of the organ, and add real-time features of the area of interest to the static 3D reconstruction using the enhancement data.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: December 25, 2018
    Assignee: St. Jude Medical International Holding S.à r.l.
    Inventors: Itay M. Kariv, Amit Cohen, Uzi Eichler, Kobi Kor
  • Patent number: 10156625
    Abstract: A method of MR imaging, wherein a portion of a body placed in the examination volume of a MR device is subjected to an imaging sequence of RF pulses and switched magnetic field gradients. The imaging sequence is a stimulated echo sequence including i) at least two preparation RF pulses (?) radiated toward the portion of the body during a preparation period, and ii) one or more reading RF pulses (?) radiated toward the portion of the body during an acquisition period temporally subsequent to the preparation period. One or more FID signals and one or more stimulated echo signals are acquired during the acquisition period. A B1 map indicating the spatial distribution of the RF field of the RF pulses within the portion of the body is derived from the acquired FID and stimulated echo signals.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: December 18, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Kay Nehrke, Peter Boernert
  • Patent number: 10156567
    Abstract: The present invention provides an in-vitro method for detecting the presence of a target substance in a biological sample by magnetic resonance, the method comprising: a) providing a mixture comprising a biological sample and a plurality of magnetic nanoparticles, wherein the magnetic nanoparticles comprise a binding agent capable of binding the target substance when the target substance is present in the biological sample; and b) determining a T2 relaxation time corresponding to magnetic nanoparticles that are bound to the target substance (T2bound) in the sample; wherein T2bound differs from the T2 relaxation time corresponding to the magnetic nanoparticles that are not bound to the target substance (T2free), and wherein T2bound is determined without physically separating magnetic nanoparticles that are bound to the target substance from the magnetic nanoparticles that are not bound to the target substance.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: December 18, 2018
    Assignee: General Electric Company
    Inventors: Ramesh Venkatesan, Arun Balasubramanian, Chandan Ramaswamy Atreya, Ravi Hedge, Ritika Uppal Mukherjee
  • Patent number: 10143389
    Abstract: Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate distinguishing diseased tissue from healthy tissue based on tissue component fractions identified using the NMR fingerprinting.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: December 4, 2018
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Mark Griswold, Anagha Deshmane, Jeffrey Sunshine
  • Patent number: 10145919
    Abstract: An imaging system comprises determination of a charge block for each building block of an MRI pulse sequence and for each readout event of the MRI pulse sequence, determination, for each charge block, of a charge per request associated with the charge block, determination, for each charge block, of an associated charge reduction based on a charge per request associated with the charge block and on a charge available to the charge block after execution of a previous charge block of the MRI pulse sequence, determination, for each charge block associated with a non-zero charge reduction, of a flip angle of a corresponding building block of the MRI pulse sequence based on a charge per request and a charge reduction associated with the charge block, and control of a radio frequency system to deliver the MRI pulse sequence based on the determined flip angles of each building block of the MRI pulse sequence corresponding to a charge block associated with a non-zero charge reduction.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: December 4, 2018
    Assignee: Siemens Healthcare GmbH
    Inventor: Wolfgang G. Rehwald
  • Patent number: 10136830
    Abstract: A method of analyzing neurophysiological data recorded from a subject is disclosed. The method comprises identifying activity-related features in the data, and parceling the data according to the activity-related features to define a plurality of capsules, each representing a spatiotemporal activity region in the brain. The method further comprises comparing at least some of the defined capsules to at least one reference capsule, and estimating a brain function of the subject based on the comparison.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: November 27, 2018
    Assignee: Elminda Ltd.
    Inventors: Amir B. Geva, Yaki Stern, Amit Reches
  • Patent number: 10132895
    Abstract: A scan condition determining apparatus determines scan conditions in a magnetic resonance imaging system. The scan condition determining apparatus includes: a setting unit for setting an imaging range, a desired spatial resolution and a desired SN ratio; and a determining unit for determining a matrix number in a frequency encode direction and a matrix number in a phase encode direction, based on the imaging range and the desired spatial resolution set by the setting unit and determining physical parameters different from the matrix number in a frequency encode direction and a matrix number in a phase encode direction, based on the determined matrix numbers, the set imaging range and the set desired SN ratio.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: November 20, 2018
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Yoshihiro Tomoda, Marie Uno
  • Patent number: 10123721
    Abstract: A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (kep) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: November 13, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Marcel Breeuwer, Massimo Mischi, Hessel Wijkstra
  • Patent number: 10126558
    Abstract: Disclosed herein are example embodiments for providing high power, narrow linewidth, high-stability laser sources. Particular embodiments are adapted for use in spin exchange optical pumping (SEOP).
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: November 13, 2018
    Assignee: UT-Battelle, LLC
    Inventors: Bo Liu, Xin Tong, Chenyang Jiang, Lee Robertson
  • Patent number: 10114097
    Abstract: In a method for operating a medical imaging examination apparatus having multiple subsystems, current ambient conditions in a scan volume of the apparatus are determined and stored in a global ambient condition parameter set. A control computer starts a scan sequence according to a selected scan protocol, and sequence control data that define different functional sub-sequences for the respective subsystems are provided to the control computer. Different effective volumes are assigned to each functional sub-sequence, and respective current sub-regions in the effective volume associated with the respective sub-sequence are determined, in which a volume optimization is to take place. Control signals for the scan sequence are calculated using the sequence control data, the global ambient condition parameter set, and the determined current sub-regions of the affected volumes, in order to optimize the functional sub-sequences at least with regard to the current sub-region of the assigned effective volume.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 30, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff, Michael Wullenweber
  • Patent number: 10101425
    Abstract: In a method for operating a medical imaging apparatus having subsystems, a control protocol assigned to a scan sequence to be performed is provided to a control computer that determines sequence control data for the control protocol, which define different functional subsequences of the scan sequence. Different effective volumes are assigned to each functional subsequence, and current ambient conditions of the apparatus are determined for the sequence control data and associated effective volumes, for a series of states of physiological processes that occur during the scan sequence. Control signals for the scan sequence are determined from the sequence control data, the effective volumes and the current ambient conditions per observed state, that optimize the functional subsequences of the scan sequence locally.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 16, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Benner, Swen Campagna, Thorsten Feiweier, Bernd Kuehn, Thorsten Speckner, Peter Speier, Daniel Nico Splitthoff
  • Patent number: 10082548
    Abstract: A circuit arrangement for driving a transmission coil arrangement with at least two individual transmission coils of a magnetic resonance system for supplying a radiofrequency signal for producing alternating electromagnetic fields over at least two channels, with in each case a digital section and an analog section, is provided. In the digital section, in an envelope generator, base frequency signals that respectively generate an envelope are provided. The circuit arrangement also includes an intermediate frequency oscillator that generates a common intermediate frequency, a frequency mixer per channel for mixing the common intermediate frequency into the base frequency signals, and in the analog sections of the channels, respectively, second frequency mixers that mix a common radiofrequency signal into each base frequency signal.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: September 25, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Holger Adolf, Rudi Baumgartl, Nikolaus Demharter, Jörg Ulrich Fontius, Rene Gumbrecht
  • Patent number: 10080508
    Abstract: A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to perform control to display a matrix representing inter-regional connectivity between a plurality of regions in a brain. The processing circuitry is configured to perform, based on an attention degree set to each of the regions, control to selectively display part of a plurality of regions arranged along a first axis of the matrix.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: September 25, 2018
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Hitoshi Yamagata, Masao Yui