Magnetic Resonance Imaging Or Spectroscopy Patents (Class 600/410)
  • Patent number: 12131477
    Abstract: Described herein is blood flow imaging based on an area under a time-enhancement curve predicted by a computer learning model. Image data comprising a plurality of corresponding images capturing at least a portion of one or both an increase phase and a decline phase of a contrast agent in a cardiovasculature of interest is inputted to a machine learning model to predict an area under a time-enhancement curve of the contrast agent within the cardiovasculature of interest, the predicted area under the time-enhancement curve representing the total sum of contrast agent concentration time product within the cardiovasculature of interest.
    Type: Grant
    Filed: April 3, 2024
    Date of Patent: October 29, 2024
    Assignee: London Health Sciences Centre Research Inc.
    Inventor: Aaron So
  • Patent number: 12121340
    Abstract: A wireless radio frequency triggered signal acquisition device includes three orthogonal pick up coils in which voltages will be induced by a time varying, spatially varying magnetic field inside a chamber of an MRI scanner. A radio frequency detection circuit detects radio frequency pulses emitted by an MRI scanner and a wireless transmission circuit transmits data from the device. A 3-axis magnetometer is used for measuring magnetic flux in the chamber of the MRI scanner. A processor uses the detected radio frequency pulses to synchronize measurements taken by the magnetometer and pickup coils to a time frame of a gradient driver hardware, thereby matching the measurements to a pulse sequence waveform. The processor further combines measurements of induced voltages in the orthogonal pick up coils and the magnetic flux with the pulse sequence waveform in order to solve for the instantaneous position and orientation of the device.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: October 22, 2024
    Assignee: University of Cape Town
    Inventor: Adam Marthinus Johannes van Niekerk
  • Patent number: 12123930
    Abstract: The disclosure relates to an RF coil device for an MR or hybrid MR-PET imaging modality, the RF coil device having a marker arrangement comprising a plurality of electromagnetic radiation markers disposed at the outer surface of its housing, wherein the electromagnetic radiation markers are adapted to reflect or emit electromagnetic radiation within the ultraviolet, visible, infrared (IR) and/or Terahertz spectrum. The disclosure also relates to detecting the position and/or orientation and/or shape of the RF coil device using electromagnetic radiation emitted from the electromagnetic radiation markers, and determining an attenuation map for the RF coil device by transforming a predefined attenuation map using the determined position and/or orientation and/or shape of the RF coil device.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: October 22, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Matthias Fenchel, Ralf Ladebeck, Johann Sukkau
  • Patent number: 12117511
    Abstract: Disclosed herein is a method of operating a medical system (100, 300). The method comprises receiving (200) pulse sequence commands (124) configured to control a magnetic resonance imaging system (302) to acquire k-space data (330) according to a Compressed Sensing magnetic resonance imaging protocol. The method further comprises receiving (202) magnetic resonance scan parameters that are descriptive of a configuration of the pulse sequence commands and a configuration of the magnetic resonance imaging system. The method further comprises receiving (204) an predicted undersampling factor (128) in response to inputting the magnetic resonance scan parameters into a neural network, wherein the neural network is configured to output the predicted undersampling factor in response to receiving magnetic resonance scan parameters. The method further comprises adjusting (206) the pulse sequence commands (130) to select or modify sampling of the k-space data based on the predicted undersampling factor.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: October 15, 2024
    Assignee: Koninklijke Philips N.V.
    Inventors: Michael Wyss, Andreas Hock, Kilian Weiss
  • Patent number: 12114988
    Abstract: A surgical guidance system has two cameras to provide stereo image stream of a surgical field; and a stereo viewer. The system has a 3D surface extraction module that generates a first 3D model of the surgical field from the stereo image streams; a registration module for co-registering annotating data with the first 3D model; and a stereo image enhancer for graphically overlaying at least part of the annotating data onto the stereo image stream to form an enhanced stereo image stream for display, where the enhanced stereo stream enhances a surgeon's perception of the surgical field. The registration module has an alignment refiner to adjust registration of the annotating data with the 3D model based upon matching of features within the 3D model and features within the annotating data; and in an embodiment, a deformation modeler to deform the annotating data based upon a determined tissue deformation.
    Type: Grant
    Filed: May 31, 2023
    Date of Patent: October 15, 2024
    Assignee: The Trustees of Dartmouth College
    Inventors: David W. Roberts, Keith D. Paulsen, Alexander Hartov, Songbai Ji, Xiaoyao Fan
  • Patent number: 12100121
    Abstract: An exemplary system, method, and computer-accessible medium for detection of structural disorder(s) of patient(s) can be provided which can include, for example, receiving magnetic resonance imaging (MRI) information of the portion(s), generating gadolinium (“Gd”) enhanced map(s) based on the MRI information using a machine learning procedure(s), and detecting the structural disorder(s) of the patient(s) based on a GD contrast of the Gd enhanced map(s). The Gd enhanced map(s) can be a full dosage Gd enhanced map. The machine learning procedure can be a convolutional neural network. The MRI information can include (i) a low-dosage Gd MRI scan(s), or (ii) a Gd-free MRI scan(s). The Gd contrast can be generated in the Gd enhanced map(s) using a T2-weighted MRI image of the portion(s). Structural disorder(s) can include Stroke, tumor, trauma, infection, Multiple sclerosis and/or other inflammatory disease.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: September 24, 2024
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Jia Guo, Scott A. Small
  • Patent number: 12089923
    Abstract: An embodiment of the present invention provides a scanning control system for a magnetic resonance imaging system, comprising: a first 3D camera, configured to capture a three-dimensional image of a scan subject located on a scanning table of the magnetic resonance imaging system; a processing device, configured to identify body position information of the scan subject based on the three-dimensional image; and a control device, configured to set scanning parameters related to a body position based on the body position information.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: September 17, 2024
    Assignee: GE Precision Healthcare LLC
    Inventors: Qingyu Dai, Yanting Huo, Jiabin Yao, Saban Kurucay, Jonathan C West, Yuwen Li
  • Patent number: 12093833
    Abstract: A visualization method for evaluating brain addiction traits, an apparatus, and a computer-readable storage medium are provided. The method includes the following. A visualization processing request is received from a client, where the visual processing request contains an image to-be-processed. The image to-be-processed is masked to obtain a perturbation image masked. The perturbation image is classified with a visualization processing model to obtain a classification result, and the classification result is calculated to obtain an evaluation value of the perturbation image, where the evaluation value of the perturbation image is less than an evaluation value of the image to-be-processed without masking. The visualization evaluation result is determined according to the evaluation value of the perturbation image. The visualization evaluation result is sent to the client.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: September 17, 2024
    Assignee: Shenzhen Institutes of Advanced Technology
    Inventors: Shuqiang Wang, Wen Yu, Chenchen Xiao, Shengye Hu
  • Patent number: 12064648
    Abstract: Systems and methods are provided for performing operations comprising: generating a radiotherapy treatment plan for treating an ablation volume comprising a myocardial scar based on a first image of a patient that is generated using contrast-enhanced magnetic resonance (MR) imaging information; identifying, based on the first image of the patient, the ablation volume comprising the myocardial scar in a second image of the patient that is generated using MR imaging information without contrast; adjusting the radiotherapy treatment plan based on the ablation volume identified in the second image of the patient; acquiring a cine image of the patient during delivery of a radiotherapy treatment fraction by a radiotherapy treatment device based on the adjusted radiotherapy treatment plan; and comparing the cine image to the second image of the patient to control delivery of a radiotherapy beam by the radiotherapy treatment device.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: August 20, 2024
    Assignee: Elekta LTD.
    Inventors: Tony Falco, Martin Emile Lachaine
  • Patent number: 12059283
    Abstract: A computer implemented method for dynamic angiographic imaging including: obtaining image data comprising a plurality of corresponding images capturing at least a portion of both an increase phase and a decline phase of a contrast agent in a blood vessel of interest; generating at least one time-enhancement curve of the contrast agent based on the image data; determining a blood flow characteristic in the blood vessel of interest based on the time-enhancement curve. Systems for implementing the method and computer readable media incorporating the method are also described.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: August 13, 2024
    Assignee: LONDON HEALTH SCIENCES CENTRE RESEARCH INC.
    Inventors: Aaron So, Ting-Yim Lee
  • Patent number: 12042229
    Abstract: A method of implanting a prosthetic component using bone density information comprises positioning a bone density reference proximate a patient, obtaining two-dimensional x-ray images of a bone of the patient including the bone density reference, determining a density of the bone from the bone density reference in the two-dimensional x-ray images, superimposing the density of the bone into a three-dimensional mean bone model to generate a patient-specific mean bone model, determining an interface between the bone and the prosthetic component based on bone density information of the patient-specific mean bone model, and implanting the prosthetic component in the bone at the interface. Determining the interface comprises evaluating bone density at the interface to place the prosthetic component, determining bone load threshold at the interface to avoid damaging the bone, and determining hardness for the prosthetic implant at the interface to avoid damaging the bone.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: July 23, 2024
    Assignee: Zimmer, Inc.
    Inventor: Kirk J. Bailey
  • Patent number: 12042235
    Abstract: A system and method for ensuring safe and tolerable insertion of a needle into a subject's body according to a preplanned or continuously monitored sequence of insertion steps. The system comprises a gripping device for gripping the needle in order to perform robotic insertion steps, yet for releasing the grip between such insertion steps, until the next insertion step is initiated. Thereby, the robot has full control of the needle during insertion steps, but does not constrain the needle between insertions, such that movement of the subject can cause neither damage nor discomfort. The gripping and insertion steps may be coordinated to keep in synchronization with the subject's breathing cycles, such that the insertion steps may be performed in the same segment of each cycle of motion of the subject's chest. The gripper can either fully disconnect from the needle, or can partially disconnect but constrain motion within limits.
    Type: Grant
    Filed: May 10, 2023
    Date of Patent: July 23, 2024
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Daniel Glozman, Gonen Daskal, Moshe Shoham, Michael Arad, Yoav Pinsky
  • Patent number: 12027253
    Abstract: At least one example embodiment provides a computer-implemented method for evaluating at least one image data set of an imaging region of a patient, wherein at least one evaluation information describing at least one medical condition in an anatomical structure of the imaging region is determined.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: July 2, 2024
    Assignee: SIEMENS HEALTHINEERS AG
    Inventors: Max Schoebinger, Michael Wels, Chris Schwemmer, Mehmet Akif Gulsun, Serkan Cimen, Felix Lades, Christian Hopfgartner, Suha Ayman, Rumman Khan, Ashish Jaiswal
  • Patent number: 12020427
    Abstract: Objective discrimination of a disease label of a depressive symptom with respect to an active state of a brain is achieved. One means for solving the problems of the present invention is to provide a discriminating device for assisting in determination of whether a subject has a depressive symptom. The discriminating device includes a storage device for storing information for identifying a classifier generated by classifier generation processing based on a signal obtained by using a brain activity detecting apparatus to measure, in advance and time-sequentially, a signal indicating a brain activity of a plurality of predetermined regions of each brain of a plurality of participants in a resting state, the plurality of participants including healthy individuals and patients with depression.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: June 25, 2024
    Assignees: ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL, HIROSHIMA UNIVERSITY
    Inventors: Giuseppe Lisi, Jun Morimoto, Mitsuo Kawato, Takashi Yamada, Naho Ichikawa, Yasumasa Okamoto
  • Patent number: 12004860
    Abstract: A method includes processing at least one input dataset (using a multi-level processing algorithm, one or more of the at least one input dataset comprising imaging data of an echocardiography of a cardiovascular system of a patient. The multi-level processing algorithm comprises a multi-task level and a consolidation-task level. An input of the consolidation-task level is coupled to an output of the multi-task level. The multi-task level is configured to determine multiple diagnostic metrics of the cardiovascular system based on the at least one input dataset. The consolidation-task level is configured to determine a fitness of the cardiovascular system of the patient.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: June 11, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Paul Klein, Ingo Schmuecking, Costin Florian Ciusdel, Lucian Mihai Itu, Tiziano Passerini, Puneet Sharma
  • Patent number: 12002212
    Abstract: An image segmentation method is provided for an electronic device. The method includes pre-training a first initial model based on a plurality of first sample images to obtain a second initial model, the plurality of first sample images including images of a plurality of human tissues, and the second initial model including distribution information of a plurality of target regions corresponding to the plurality of human tissues, training the second initial model based on a plurality of second sample images to obtain an image segmentation model, image information of the plurality of second sample images including at least distribution information of a plurality of target regions corresponding to a target human tissue reflected in the second sample images, and feeding a first image to the image segmentation model, and segmenting, by using the image segmentation model, the first image according to the image information to output a second image.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: June 4, 2024
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventor: Sihong Chen
  • Patent number: 12000917
    Abstract: A system and method for producing a series of time-resolved magnetic resonance (MR) images is set forth. The system can perform method steps of encoding spatial information into an MRI signal by manipulating a phase of the MRI signal within an MRI system, generating and outputting a phase-encoded MRI signal over time by digitizing a plurality of time points in the MRI signal, repeating the generating and outputting step for a plurality of phase-encoded signals, each phase-encoded signal in synchrony with a trigger, producing a plurality of digitized time points, and reconstructing a series of time resolved MR images, each image of the series of MR images at one specific time point selected from the plurality of digitized time points for each phase-encoded step. Each image in the series of time-resolved MR images corresponding to a specific time point in a cyclic event.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: June 4, 2024
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Xiaohong Joe Zhou, Zheng Zhong, Meryem Muge Karaman
  • Patent number: 11992305
    Abstract: A magnetic resonance imaging apparatus captures a morphology image and a function image that are captured with respect to an equal imaging region of an object under examination. Processing for deforming the morphology image is performed using a deformation parameter and moving positions of structural objects included in the morphology image to respective positions of structural objects of a previously determined standard morphology. Then, the function image is deformed using a value of the deformation parameter used in deforming the morphology image to cause a position of a region included in the function image to coincide with a position of a corresponding region of the standard morphology or by using the standard morphology in an opposite direction using the value of the deformation parameter to cause a position of a region of the structural object thereof to coincide with a position of a corresponding region included in the function image.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: May 28, 2024
    Assignee: FUJIFILM HEALTHCARE CORPORATION
    Inventors: Yasuo Kawata, Masahiro Takizawa, Nobuyuki Yoshizawa
  • Patent number: 11995744
    Abstract: An imaging method may include obtaining original imaging data of an object in a raw-data domain including original time of flight (TOF) information. The method may also include gating the original imaging data into a plurality of data sets in the raw-data domain. The method may also include determining a plurality of motion vector fields based on the plurality of data sets. The method may also include generating corrected imaging data in the raw-data domain by performing motion correction on at least one of the plurality of data sets based on the original TOF information and at least one corresponding MVF of the plurality of MVFs. The method may also include generating one or more target images of the object by performing, based on the corrected imaging data, image reconstruction.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: May 28, 2024
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Tao Feng, Yang Lyu, Hao Liu, Gang Yang
  • Patent number: 11992304
    Abstract: A magnetic resonance imaging (MRI) system and methods for use with a medical, e.g., a surgical, robotic system, involving an MRI apparatus configured to operate with the surgical robotic system, the MRI apparatus having at least one low-field magnet, the at least one low-field magnet configured to generate a low magnetic field, and the low magnetic field comprising a magnetic flux density in a range of approximately 0.1 Tesla (T) to approximately 0.5 T, whereby a standoff between the MRI apparatus and the surgical robotic system is reduced.
    Type: Grant
    Filed: September 8, 2020
    Date of Patent: May 28, 2024
    Assignee: SYNAPTIVE MEDICAL INC.
    Inventors: Cameron Anthony Piron, Alexander Gyles Panther, Thanh Vinh Vuong, Diana Lee
  • Patent number: 11989883
    Abstract: The present application discloses a system and a device for functional connectivity matrix processing based on feature selection using a filtering method, which comprises the following steps: acquiring a preprocessed resting state brain functional magnetic resonance image of a subject; extracting time series; calculating a Pearson correlation coefficient to obtain a Pearson correlation coefficient matrix; vectorizing the Pearson correlation coefficient matrix; calculating quantitative correlation indices using a filtering method, and selecting a quantitative correlation index based on a preset threshold; performing weighting processing a selected functional connectivity feature by using the corresponding quantitative correlation index with high correlation with a disease diagnosis result to obtain a functional connectivity matrix; and obtaining a prediction result from the functional connectivity matrix.
    Type: Grant
    Filed: July 27, 2023
    Date of Patent: May 21, 2024
    Assignee: ZHEJIANG LAB
    Inventors: Jingsong Li, Jun Li, Baochen Wang, Zhuoxin Li, Yu Tian, Tianshu Zhou
  • Patent number: 11986280
    Abstract: Systems and methods are disclosed for diagnosing and treatment planning for vascular steal syndromes and retrograde flow, One method includes receiving a reference blood flow direction at a location in a reference vasculature; determining a patient-related brood flow direction at a location in a patient's vasculature corresponding to the location in the reference vasculature; determining a difference in direction, between the reference blood flow direction of the reference vasculature and the patient-related blood flow direction of the patient's vasculature; and generating a representation of the location in the patient's vasculature associated with the difference in direction between the reference blood flow direction and the patient-related blood flow direction, or generating a treatment recommendation for the patient's vasculature based on the difference in direction between the reference blood flow direction and the patient-related blood flow direction.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: May 21, 2024
    Assignee: HeartFlow, Inc.
    Inventors: Leo J. Grady, Charles A. Taylor
  • Patent number: 11983876
    Abstract: In a method for determining a type of characteristic eye movement of the eyes of a patient, the patient is provided with an optokinetic stimulus for the characteristic eye movement, a medical image of the brain of a patient also including the eyes of the patient is generated. An amount of a displacement of an optic nerve of the patient may be determined based on the medical image and a type of a characteristic eye movement may be determined based on the velocity of eye movement for the determined amount of displacement of the optic nerve. In a method for training an artificial intelligence based algorithm for determining an amount of a displacement of an optic nerve of a patient, the algorithm may be trained based on at least one medical image.
    Type: Grant
    Filed: August 4, 2023
    Date of Patent: May 14, 2024
    Assignee: Siemens Healthineers AG
    Inventor: Nisarga Nagaraj
  • Patent number: 11978146
    Abstract: The present invention relates to a three-dimensional reconstructing method of a 2D medical image. A three-dimensional reconstructing device includes: a communicator for receiving sequential 2D images with an arbitrary slice gap; a sliced image generator for generating at least one sliced image positioned between the 2D images based on a feature point of the adjacent 2D images; and a controller for reconstructing the 2D image into a 3D image by use of the generated sliced image and providing the 3D image.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: May 7, 2024
    Assignee: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Dong Young Lee, Yu Kyeong Kim, Jae Sung Lee, Min Soo Byun, Seong A Shin, Seung Kwan Kang
  • Patent number: 11966816
    Abstract: Aspects of generating error-resistant quantum control pulses from geometrical curves are described. In some embodiments, a closed space curve is parameterized for a target gate operation of a quantum computing device. The closed space curve corresponds to an evolution operator of a time-dependent Schrödinger equation associated with the target gate operation. A control field definition is identified for the target gate operation based at least in part on a geometrical analysis of the evolution operator of the time-dependent Schrödinger equation. The target gate operation is implemented for the quantum computing device based on the control field definition.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: April 23, 2024
    Assignee: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
    Inventors: Edwin Barnes, Junkai Zeng
  • Patent number: 11937908
    Abstract: A method of performing magnetic resonance imaging of a body includes a) immerging the body in a static and substantially uniform magnetic field; b) exciting nuclear spins inside the body using at least one radio-frequency pulse; c) applying to the body a time-varying magnetic field gradient defining at least one trajectory (ST) in k-space and simultaneously acquiring samples of a magnetic resonance signal so as to perform a pseudo-random sampling (KS) of the k-space; and d) applying a sparsity-promoting nonlinear reconstruction algorithm for reconstructing a magnetic resonance image of the body; wherein, at least in a low-spatial frequency region of the k-space, the distance between any two adjacent points belonging to a same trajectory is lower than 1/FOV, FOV being the size of a field of view of the reconstructed image. A magnetic resonance imaging apparatus for carrying out such a method is also provided.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: March 26, 2024
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES PARIS, FRANCE, UNIVERSITÉ PARIS-SACLAY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Nicolas Chauffert, Philippe Ciuciu, Jonas Kahn, Carole Lazarus, Alexandre Vignaud, Pierre Weiss
  • Patent number: 11931149
    Abstract: Described herein is a method of using functional MRI (fMRI) for determining brain activation patterns for a group of subjects in response to different odor-elicited feelings (i.e., conscious emotions). A method for preparing a perfume by using the method of the present invention and a consumer product including said perfume are also described herein.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: March 19, 2024
    Assignee: FIRMENICH SA
    Inventors: Aline Pichon, Patrik Vuilleumier, Sylvain Delplanque, David Sander, Isabelle Cayeux, Christelle Porcherot, Maria Inés Velazco, Christian Margot
  • Patent number: 11933871
    Abstract: According to one embodiment, MRI apparatus includes processing circuitry and an imaging device. The processing circuitry is configured to acquire at least one of body size information relating to a size of an object and breath-hold information relating to a breath-holdable time of the object. The processing circuitry is further configured to determine an imaging condition to be performed on the object based on the at least one of the body size information and the breath-hold information. The imaging device performs imaging of the object in accordance with the determined imaging condition.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: March 19, 2024
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Shinya Ozawa, Takeshi Ishimoto
  • Patent number: 11935158
    Abstract: A method for performing real-time magnetic resonance (MR) imaging on a subject is disclosed. A prep pulse sequence is applied to the subject to obtain a high-quality special subspace, and a direct linear mapping from k-space training data to subspace coordinates. A live pulse sequence is then applied to the subject. During the live pulse sequence, real-time images are constructed using a fast matrix multiplication procedure on a single instance of the k-space training readout (e.g., a single k-space line or trajectory), which can be acquired at a high temporal rate.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: March 19, 2024
    Assignee: Cedars-Sinai Medical Center
    Inventors: Anthony Christodoulou, Zhaoyang Fan, Debiao Li, Pei Han
  • Patent number: 11921182
    Abstract: Systems and methods provide accelerated MR thermometry utilizing prior knowledge about the images to be reconstructed from incomplete k-space data, thereby facilitating accurate reconstruction. In various embodiments, missing data is computationally estimated using a machine learning algorithm such as a neural network, and an image is generated based on iteratively updated estimated missing information.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: March 5, 2024
    Assignee: INSIGHTEC LTD.
    Inventors: Yuval Zur, Boaz Shapira, Yoav Levy
  • Patent number: 11903691
    Abstract: A method to automatically align magnetic resonance (MR) scans for diagnostic scan planning includes acquiring a three-dimensional (3D) localizer image of an anatomical object. One or more initial landmarks are identified in the 3D localizer image using a landmarking engine. One or more main axes associated with the anatomical object are identified based on the one or more initial landmarks. The 3D localizer image is registered to a canonical space based on the main axes associated to yield a registered 3D localizer image. The landmarking engine is applied to the registered 3D localizer image to yield one or more updated landmarks. A plurality of reference points for performing a MR scan are computed based on the one or more updated landmarks.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: February 20, 2024
    Assignee: Siemens Healthineers AG
    Inventors: Fitsum Aklilu Reda, Yiqiang Zhan, Martin Harder
  • Patent number: 11893662
    Abstract: An imaging system includes a sensor configured to receive imaging data, where the imaging data comprises k-space data from a magnetic resonance imaging (MRI) scan of a patient. The imaging system also includes a processor operatively coupled to the sensor and configured to identify a degree of interaction between measured points of the k-space data located at a radius from a center of k-space. The processor is also configured to determine, based at least in part on the degree of interaction between the measured points, density weights for a density compensation filter. The processor is also configured to apply the density compensation filter to the k-space data to generate filtered k-space data. The processor is further configured to generate an MRI image of the patient based at least in part on the filtered k-space data.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: February 6, 2024
    Assignee: Northwestern University
    Inventors: Kyungpyo Hong, Daniel Kim
  • Patent number: 11883202
    Abstract: One example of a system includes a local user system to interact with an implantable medical device and a local input device communicatively coupled to the local user system to generate local events. To operate the local user system, the local user system is to receive local events from the local input device and remote events from a remote user system communicatively coupled to the local user system via a medical device remote access system. The local user system is to process a local event and ignore a remote event in response to receiving a local event and a remote event simultaneously.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: January 30, 2024
    Assignee: Medtronic, Inc.
    Inventors: Corey E. Ney, Kent D. Magaard
  • Patent number: 11867783
    Abstract: A system and method are provided for analysing a functional magnetic resonance imaging (MRI) scan representing a time-sequence, comprising t time points, of images comprising v voxels, where each scan can be represented by a data matrix X?t×v. The method comprises modelling the scan data X as the convolution of neural activation time courses N?+t×v and a haemodynamic filter ?, and performing an inverse operation to estimate N from X and ?. The method further compasses decomposing the neural activation time courses N into multiple brain network components by representing N as the product of a first matrix H defining, for each component, a spatial map of the voxels belonging to that component, and a second matrix W defining, for each component, the time sequence of activation of that component during the scan. In other implementations, the matrix decomposition may be performed before the deconvolution.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: January 9, 2024
    Assignee: King's College London
    Inventors: Michael Hutel, Sebastien Ourselin
  • Patent number: 11857275
    Abstract: Systems and methods for neuronavigation in accordance with embodiments of the invention are illustrated. Targeting systems and methods as described herein can generate personalized stimulation targets for the treatment of mental conditions. In many embodiments, direct stimulation of a personalized the stimulation target indirectly impacts a brain structure that is more difficult to reach via the stimulation modality. In various embodiments, the mental condition is major depressive disorder. In a number of embodiments, the mental condition is suicidal ideation.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: January 2, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Nolan R. Williams, Adi Maron-Katz
  • Patent number: 11857288
    Abstract: A method of cardiac strain analysis uses displacement encoded magnetic resonance image (MRI) data of a heart of the subject and includes generating a phase image for each frame of the displacement encoded MRI data. Phase images include potentially phase-wrapped measured phase values corresponding to pixels of the frame. A convolutional neural network CNN computes a wrapping label map for the phase image, and the wrapping label map includes a respective number of phase wrap cycles present at each pixel in the phase image. Computing an unwrapped phase image includes adding a respective phase correction to each of the potentially-wrapped measured phase values of the phase image, and the phase correction is based on the number of phase wrap cycles present at each pixel. Computing myocardial strain follows by using the unwrapped phase image for strain analysis of the subject.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: January 2, 2024
    Assignee: University of Virginia Patent Foundation
    Inventors: Sona Ghadimi, Changyu Sun, Xue Feng, Craig H. Meyer, Frederick H. Epstein
  • Patent number: 11844599
    Abstract: An embodiment of the present invention provides a scanning control system for a magnetic resonance imaging system, comprising: a first 3D camera, configured to capture a three-dimensional image of a scan subject located on a scanning table of the magnetic resonance imaging system; a processing device, configured to identify body position information of the scan subject based on the three-dimensional image; and a control device, configured to set scanning parameters related to a body position based on the body position information.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: December 19, 2023
    Assignee: GE Precision Healthcare LLC
    Inventors: Qingyu Dai, Yanting Huo, Jiabin Yao, Saban Kurucay, Jonathan C West, Yuwen Li
  • Patent number: 11848098
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for determining anomalous brain data. One of the methods includes obtaining brain data characterizing brain activity of a patient; for each of a plurality of pairs of parcellations comprising a first parcellation and a second parcellation, processing the brain data to generate a correlation between the brain activity of the first and second parcellations; obtaining second connectivity data that characterizes, for each of the plurality of pairs of parcellations, a normal range of correlations between the brain activity of the first and second parcellations; identifying one or more of the plurality of pairs of parcellations for which the correlation between brain activity of the first and second parcellations is outside of the corresponding normal range of correlations; and providing data characterizing the one or more identified pairs of parcellations for display to a user on a graphical interface.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: December 19, 2023
    Assignee: Omniscient Neurotechnology Pty Limited
    Inventors: Michael Edward Sughrue, Stephane Philippe Doyen, Peter James Nicholas
  • Patent number: 11842427
    Abstract: A method and system for reducing or removing motion artefacts in magnetic resonance (MR) images, the method including the steps of: receiving a motion corrupted MR image; determining a corrected intensity value for each pixel in the motion corrupted MR image by using a neural network; and generating a motion corrected MR image based on the determined corrected intensity values for the pixels in the motion corrupted MR image.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: December 12, 2023
    Inventors: Kamlesh Pawar, Zhaolin Chen, Nadim Joni Shah, Gary Francis Egan
  • Patent number: 11841411
    Abstract: In a method and apparatus for acquiring and reconstructing a four-dimensional dynamic magnetic resonance (MR) image data record, MR data are continuously acquired by radial scanning of an examination region along radial k-space lines, and a dynamic region of the examination region, in which said dynamic procedure is relevant, is determined, as well as a non-dynamic region, which is not relevant to the dynamic procedure. Static image data are reconstructed from all of the acquired MR data, and image data therein originating from the non-dynamic region are marked and are then not used for reconstructing a dynamic image data record for the dynamic region.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: December 12, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Ralf Kartaeusch, Simon Bauer
  • Patent number: 11842491
    Abstract: A method of generating a quantitative characterization of injury presence and status of spinal cord tissue using an adaptive CNN system for use in diagnostic assessment, surgical planning, and therapeutic strategy comprises preprocessing for artifact correction of diffusion based, spinal cord MRI data, training an adaptive CNN system with healthy and abnormal (injured/pathologic) spinal cord images obtained by imaging a population of healthy, typically developed spinal cord subjects and subjects with spinal cord injury, evaluating a novel, diffusion-based MRI image for injury biomarkers using the adaptive CNN system, generating a three-dimensional predictive axonal damage map for quantitative characterization and visualization of the novel, diffusion-based MRI image, and transmitting the sets of healthy and injured spinal cord images back to a central database for continued improvement of the adaptive CNN system training. A system for defining a predictive spinal axonal damage map is also described.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: December 12, 2023
    Assignee: Thomas Jefferson University
    Inventors: Christopher J. Conklin, Feroze B. Mohamed, Devon M. Middleton, Mahdi Alizadeh
  • Patent number: 11835604
    Abstract: A method for ascertaining at least one of a position or an orientation of an MR local coil unit for arrangement inside a main magnetic field includes providing a first 3D relative position of a reference sensor system in relation to the main magnetic field; receiving an acceleration vector from at least one acceleration sensor; retrieving a distance vector describing a fixed relative position as a function of the received acceleration vector; calculating a second 3D relative position of the at least one acceleration sensor in relation to the main magnetic field based on the first 3D relative position and the retrieved distance vector; and ascertaining the at least one of the position or the orientation of the MR local coil unit using the first 3D relative position and the second 3D relative position.
    Type: Grant
    Filed: July 26, 2022
    Date of Patent: December 5, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Johann Sukkau, Volker Matschl, Steffen Schroeter
  • Patent number: 11837354
    Abstract: Described herein is medical imaging technology for concurrent and simultaneous synthesis of a medical CA-free-AI-enhanced image and medical diagnostic image analysis comprising: receiving a medical image acquired by a medical scanner in absence of contrast agent enhancement; providing the medical image to a computer-implemented machine learning model; concurrently performing a medical CA-free-AI-enhanced image synthesis task and a medical diagnostic image analysis task with the machine learning model; reciprocally communicating between the image synthesis task and the image analysis task for mutually dependent training of both tasks. Methods and systems and non-transitory computer readable media are described for execution of concurrent and simultaneous synthesis of a medical CA-free-AI-enhanced image and medical diagnostic image analysis.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: December 5, 2023
    Assignee: London Health Sciences Centre Research Inc.
    Inventor: Shuo Li
  • Patent number: 11815579
    Abstract: According to one embodiment, a magnetic resonance imaging apparatus includes sequence control circuitry and processing circuitry. The sequence control circuitry performs under-sampled data acquisition whose sample points are located at an equal interval in k-space and acquires k-space frames. The processing circuitry generates a plurality of k-space frames related to a plurality of time resolutions based on the k-space frames. In each of the plurality of k-space frames, the sample points are located at an equal interval, and the interval differs for each of the plurality of k-space frames. The processing circuitry generates a time-series image based on the plurality of k-space frames.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: November 14, 2023
    Assignee: Canon Medical Systems Corporation
    Inventor: Hidenori Takeshima
  • Patent number: 11808832
    Abstract: A computer-implemented method for generating an artifact corrected reconstructed contrast image from magnetic resonance imaging (MRI) data is provided. The method includes inputting into a trained deep neural network both a synthesized contrast image derived from multi-delay multi-echo (MDME) scan data or the MDME scan data acquired during a first scan of an object of interest utilizing a MDME sequence and a composite image, wherein the composite image is derived from both the MDME scan data and contrast scan data acquired during a second scan of the object of interest utilizing a contrast MRI sequence. The method also includes utilizing the trained deep neural network to generate the artifact corrected reconstructed contrast image based on both the synthesized contrast image or the MDME scan data and the composite image. The method further includes outputting from the trained deep neural network the artifact corrected reconstructed contrast image.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: November 7, 2023
    Assignee: GE Precision Healthcare LLC
    Inventors: Sudhanya Chatterjee, Dattesh Dayanand Shanbhag
  • Patent number: 11806196
    Abstract: A head stabilization device or HFD includes a plurality of integrated markers. The HFD may be in the form of a skull clamp, vacuum bag, combinations thereof, or other supporting structure. The integrated markers include MRI markers detectable by an MRI scanner and fiducial markers detectable by a registration tool of a navigation system. The markers provide a reference point relative to an operation site in a patient for use in a navigation guided procedure and aid in registering or calibrating the location of the patient with captured images used in the navigation guided procedure.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: November 7, 2023
    Assignees: pro med instruments GmbH, Brainlab AG
    Inventors: Matthias E. Schuele, Sascha Kubis, Roman Maier
  • Patent number: 11796611
    Abstract: A method for medical imaging may include determining a posture of an object and obtaining a first parameter of a pulse sequence to be applied to the object. The method may also include determining, based on the posture and the first parameter, a SAR distribution model and estimating, based on the SAR distribution model and a second parameter of the pulse sequence to be applied, a SAR distribution associated with the object under the pulse sequence to be applied. The second parameter is associated with calibration of the pulse sequence to be applied. The method may further include determining whether the estimated SAR distribution meets a condition and causing, in response to a result of the determination that the estimated SAR distribution associated with the object meets the condition, a scanner to perform an MR scan on the object according to the pulse sequence.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: October 24, 2023
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Zhenhua Shen, Qiang He
  • Patent number: 11779295
    Abstract: The present invention discloses a method and a system of vertebral compression fracture detection. The method of vertebral compression fracture detection includes: recombining a plurality of anatomical images captured in at least a spine segment of a target individual into a 3D image; using a multi-planar reconstruction method to reformat the 3D image to obtain at least one sagittal reformatted image; using a classification model to determine whether the sagittal reformatted image covers the middle section of the vertebral column or not; using a vertebral detection method to detect each vertebral body in the sagittal reformatted image covering the middle section of the vertebral column; using a keypoint localization method to localize a plurality of keypoints of each vertebral body which was detected in the sagittal reformatted image; evaluating the compression fracture grade of each vertebral body in the sagittal reformatted image.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: October 10, 2023
    Assignees: QUANTA COMPUTER INC., TAIPEI MEDICAL UNIVERSITY
    Inventors: Wing P. Chan, Ai-Ling Hsu, Kuan-Chieh Huang, Yi-Ting Peng, Ching-Chung Kao
  • Patent number: 11771364
    Abstract: A bone density estimating method, comprising: acquiring, by an MR scanning device, a magnetic resonance, MR, sequence of a body portion, wherein the MR sequence comprises quantitative information of the body portion; generating, by a processing circuit, an MR image of the body portion based on the MR sequence, wherein each voxel of the MR image represents a volume of the body portion; identifying, by the processing circuit, a part of the MR image representing a bone portion of the body portion; for a voxel of the identified part of the MR image, estimating a bone density of a volume of the bone portion represented by the voxel, based on a quantitative value of the voxel. The quantitative information of the body portion comprises a proton density.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: October 3, 2023
    Assignee: SYNTHETICMR AB (PUBL)
    Inventor: Marcel Warntjes
  • Patent number: 11763948
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating a mental health prediction for a patient using a centrality ranking of the brain of the patient. One of the methods includes obtaining brain data of a patient, wherein the brain data comprises, for each of a plurality of pairs of parcellations formed from a set of parcellations where each pair comprises a first parcellation and a second parcellation, data characterizing a number of tracts connecting the first parcellation and the second parcellation; determining a network graph from the brain data; generating, for each of a plurality of nodes in the network graph, a measure of centrality of the node; determining a centrality ranking of the plurality of nodes of the network graph according to the respective measures of centrality; generating a mental health prediction for the patient using the determined centrality ranking.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: September 19, 2023
    Assignee: Omniscient Neurotechnology Pty Limited
    Inventors: Michael Edward Sughrue, Stephane Philippe Doyen, Peter James Nicholas, Hugh Monro Taylor