Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract: A diagnostic catheter and method of use for analyzing tissue is provided. A method for analyzing tissue in accordance with one embodiment of the present invention includes inserting a catheter having a sensor at its distal end into the body of a patient, applying suction through the catheter to secure the tissue to the catheter and then analyzing the tissue with the sensor. An apparatus for analyzing tissue within the body of a patient in accordance with an alternative embodiment of the present invention is also provided. This alternative embodiment includes a catheter having a first end and a second end, the first end having an orifice and a sensor, the catheter also having a lumen.

Abstract: Localization of a coil is provided for magnetic resonance (MR)-guided intervention. A multi-scale decomposition and characteristic transitions in the power spectra for the coil are used to determine a distribution of likelihood of the coil being at each of various locations and/or to determine a confidence in the position determination. For example, the power spectra along each axis is used to generate a likelihood distribution of the location of the coil. The power spectra are decomposited at different scales. For each scale, the modulus maxima reflecting transitions in the power spectra are matched using various criteria. A likelihood is calculated for each of the matched candidates from characterizations of the matched candidates. The likelihood distribution is determined from a combination of the likelihoods from the various scales.

Abstract: An MRI-compatible tip assembly for an MRI-compatible medical device includes a first tubular member, a second tubular member, a ring electrode, and a tip electrode. The tip electrode proximal end is secured to the first tubular member distal end. The second tubular member distal end is inserted through the ring electrode and is secured to the first tubular member proximal end. When assembled, the tip assembly is a substantially rigid structure. Each tubular member has a recessed portion for a tracking coil.

Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

Abstract: A magnetic resonance imaging apparatus controls image reconstruction based on magnetic resonance signals collected when a peak of detected respiration level falls within an allowable range which changes based on a change in a plurality of peak values of a plurality detected respiration levels.

Abstract: A system and method includes a medical device configured to be inserted into a subject having an imaging coil coupled thereto and configured to be inserted into the subject during a medical procedure to provide tracking information regarding a position of the medical device. A circuit is connected to the imaging coil to switch the circuit between an energy harvesting configuration and an image data acquisition configuration. The circuit includes an energy harvesting path and an imaging data path connected to the imaging coil that are electrically distinct. An energy storage device is connected to receive power delivered along the energy harvesting path when the circuit is in the energy harvesting configuration. An amplifier is connected to receive power from the energy storage device and receive imaging data signals from the imaging coil over the imaging data path to thereby amplify the imaging data signals.

Abstract: Landmark directional guidance is provided to an operator of an endoscopic device by displaying graphical representations of vectors adjacent a current image captured by an image capturing device disposed at a tip of the endoscopic device and being displayed at the time on a display screen, wherein the graphical representations of the vectors point in directions that the endoscope tip is to be steered in order to move towards associated landmarks such as anatomic structures in a patient.

Abstract: In a method for detecting rotational orientation and position tracking of an inductively coupled RF (ICRF) coil using a transmit array system, a conventional body birdcage coil is used, but the quadrature hybrid is eliminated to use the two excitation-channels separately. The transmit array system provides RF excitations such that the body birdcage coil creates linearly polarized and circulating RF pulses instead of a conventional rotational forward polarized excitation. Inductively coupled RF (ICRF) coils can be constructed on catheters for detecting rotational orientation and tracking purposes. The modifications on anatomy and ICRF coil images are different due to the RF excitation scheme such that the ICRF coil can be separated from the anatomy in real-time. After separating the ICRF coil from the anatomy, a color-coded image can be reconstructed, for example.

Abstract: An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.

Abstract: A fluid path system includes a vial containing a pharmaceutical product therein. A dissolution fluid path is also included in the fluid path system, the dissolution fluid path having an output end in fluid communication with the vial and an input end attached to a pressure vessel containing a dissolution medium. A delivery fluid path is also included in the system having a first end hermetically attached to the vial to transport therefrom a mixture of dissolved pharmaceutical product and dissolution medium and a second end connected to a receiving vessel to receive the mixture. A dissolution fluid path valve is positioned between the pressure vessel and the dissolution fluid path to control flow of the dissolution medium, and a delivery fluid path valve is also included in the fluid path system to control flow of the mixture from the delivery fluid path to the receiving vessel.

Abstract: An imaging medical apparatus has at least one device to identify a plane in space. The device has: a light source that emits a fan-shaped light beam, the light source is rotatable around a light source rotation axis. The device also has a mirror that reflects the fan-shaped light beam, the mirror being rotatable around a mirror rotation axis and encompassing a mirror plane. The mirror rotation axis and the surface normal of the mirror plane enclose an angle greater than 0° and less than 90°.

Abstract: Systems and methods for sensing external magnetic fields in implantable medical devices are provided. One aspect of this disclosure relates to an apparatus for sensing magnetic fields. An apparatus embodiment includes a sensing circuit with at least one inductor having a magnetic core that saturates in the presence of a magnetic field having a prescribed flux density. The apparatus embodiment also includes an impedance measuring circuit connected to the sensing circuit. The impedance measuring circuit is adapted to measure impedance of the sensing circuit and to provide a signal when the impedance changes by a prescribed amount. According to an embodiment, the sensing circuit includes a resistor-inductor-capacitor (RLC) circuit. The impedance measuring circuit includes a transthoracic impedance measurement module (TIMM), according to an embodiment. Other aspects and embodiments are provided herein.

Abstract: An interface device provides one or more electrical connection points disposed on a connector sleeve. The connection points provide electrical communication between a lead connector end of an implantable medical lead and one or more leads of a testing device in such a manner as to minimize potential damage to the lead connector end.

Abstract: A medical probe includes a flexible insertion tube having a distal end for insertion into a body cavity and having a proximal end. The probe further includes an electrode attached to the distal end of the insertion tube and configured to make electrical contact with tissue in the body cavity. An electrical lead runs through the insertion tube between the distal and proximal ends. In addition a coil is electrically coupled between the electrode and the lead in the insertion tube so as to define a resonant circuit having a resonant frequency in a range between 1 MHz and 300 MHz.

Abstract: A tracking device configured to be coupled to an interventional instrument and tracked by a magnetic resonance imaging system is provided. The tracking device includes, for example, paramagnetic and diamagnetic components that form first and second tracking members. When the tracking device is adjusted into a first arrangement, the tracking device will produce a local magnetic field in the presence of the magnetic field of an MRI system that is measurable by the MRI system. However, when the tracking device is adjusted into a second arrangement, the local magnetic field produced by the tracking device is reduced relative to the first arrangement, wherein the reduced local magnetic field produces substantially no magnetic field disturbances detectable by the MRI system. Images may be acquired of a patient in which the tracking device has been introduced and, using a numerical fitting method, an accurate location of the tracking device can be determined.

Abstract: A method and apparatus for optimizing a computer assisted procedure is provided. A method and apparatus for performing a procedure is also provided. Data can be accessed and processed to optimize and perform a procedure. The data can be augmented or supplemented with patient specific data.

Abstract: An electrically conductive transmission line is configured for use in the magnet bore of a magnetic resonance system and includes at least one inductive coupling element for coupling at least two lead segments of the line. The coupling element includes a paramagnetic and/or ferromagnetic material.

Abstract: A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity. An array of spatially separated coils is positioned within the distal end. A processor is configured to process respective signals generated by the coils in response to magnetic resonance of tissue in the body cavity, and to process the signals while applying a phase delay responsive to a separation between the coils so as to image the tissue.

Abstract: One or more light beam endowed with photonic orbital angular momentum generating devices are mounted at preselected locations on an insertable instrument to hyperpolarize nuclear magnetic dipoles in a region of interest. The hyperpolarized nuclear magnetic dipoles are caused to resonate, generating magnetic resonance signals. A controller controls gradient coils to induce a magnetic field gradient across the region of interest, such that the frequency of the resonance signals is indicative of spatial positions. A frequency-to-position decoder converts the resonance signal frequencies into spatial positions. A video processor combines the spatial positions and a portion of a diagnostic image from a diagnostic image memory into a combined image which depicts the location of the region of interest or a portion of the instrument marked on the diagnostic image and displays the combined image on a monitor.

Abstract: A microcoil is manufactured by rolling a trace unit in such a way as to form at least one winding. The trace unit is comprised of a conductive trace attached to a flexible insulating film. A preferred embodiment of the microcoil contains both a first winding and a second winding electrically connected and spaced apart by ajoining portion. The microcoil may be used for internal magnetic resonance imaging of patient by attaching the microcoil to a catheter.

Abstract: A medical lead is configured to be implanted into a patient's body and comprises a lead body, and an electrode coupled to the lead body. The electrode comprises a first section configured to contact the patient's body, and a second section electrically coupled to the first section and configured to be capacitively coupled to the patient's body.

Abstract: A novel method and system for employing device tracking with a magnetic resonance imaging system. In accordance with one aspect of the present technique, a method for tracking the location of a device and generating an image using magnetic resonance imaging includes applying a combined imaging and tracking pulse sequence, in the presence of a magnetic field gradient, wherein the combined imaging and tracking sequence comprising a radiofrequency excitation pulse. The method further includes collecting tracking data based on a magnetic resonance tracking signal resulting from the radiofrequency excitation pulse, wherein the magnetic resonance tracking signal is returned from a tracking coil mounted in the device. The method also includes collecting imaging data based on a magnetic resonance imaging signal resulting from the radiofrequency excitation pulse, wherein the magnetic resonance imaging signal is returned from an imaging coil.

Abstract: An electrically conductive transmission line for transmitting RF signals, in particular for transmitting MR signals between a transmission and/or receiving coil and a transmitting and/or receiving unit, by which separate known matching networks can be avoided or reduced. A transmission line is proposed comprising a plurality of lead segments coupled by transformers having a transformer impedance ZL placed between two neighboring lead segments, wherein for power matching of the two transformers placed at opposite ends of a lead segment, the lead segment has a lead segment impedance Z0 or a dielectric constant ?r and wherein the lead segment has a short length l. Thus, the lead segments themselves provide the matching of the transformers, and separate matching circuits are no longer needed.

Abstract: The present application discloses a guidewire for magnetic resonance imaging with a single channel design to reduce complexity and to provide conspicuous tip visibility under MRI. In one embodiment, a guidewire body includes an antenna formed from a rod and a helical coil coupled together. The helical coil can have multiple windings without any gaps between the windings. The rod passes through the windings of the helical coil and is coupled to the helical coil using a conductive joint positioned at an end of the rod and at an end of the helical coil. Insulation can be positioned between the rod and the windings of the helical coil. The configuration allows visibility of the antenna along the length of a rod, except where it enters the windings of the coil. Thus, the tip visibility is enhanced as being separated from the rod.

Abstract: In a magnetic resonance imaging apparatus according to an embodiment, a transmitting coil applies a radio-frequency magnetic field to a subject placed in a static magnetic field. A receiving coil receives a magnetic resonance signal emitted from the subject owing to an application of the radio-frequency magnetic field. A balun is connected to the receiving coil, and suppresses an unbalanced current induced in the receiving coil. An overheat protection circuit indicates that the balun is abnormal when a temperature of the balun exceeds a temperature threshold. An imaging control unit stops imaging when the overheat protection circuit indicates an abnormality of the balun.

Abstract: An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.

Abstract: A system and method of both tracking a medical device and generating an image in real time from the same set of radial data. A multi-mode medical device system having tracking, imaging, and visualizing capabilities is coupled to an MR scanner and multiple-echo VIPR acquisition sequence is applied to simultaneously provide conventional real-time imaging of the target region using an external coil, 3D tip-tracking information, and a localized higher-quality image showing the region surrounding the medical device using an internal multi-mode coil.

Abstract: Certain embodiments of the present invention provide a method for correlating data including: receiving from a tracking subsystem a first data set including a tracked position of an object; receiving from an imaging subsystem a second data set including an image of the object; and comparing automatically at least a portion of the first data set with at least a portion of the second data based at least in part on the tracked position of the object and the image of the object. In an embodiment, the comparing automatically the first data set with the second data set is performable in real-time. In an embodiment, the method further includes registering the first data set with the second data set. In an embodiment, the tracking subsystem tracks the object electromagnetically, at least in part. In an embodiment, the imaging subsystem includes an x-ray imaging subsystem. In an embodiment, the first data set is generatable by the tracking subsystem substantially in real-time.

Abstract: An MR process locates a medical instrument with an attached microcoil in the examination volume of an MR device. The microcoil is part of a resonant circuit matched to the resonant frequency of the MR device and having no external controls. At least two temporally successive high frequency pulses (RF) are generated within the examination volume. After each of the high frequency pulses (RF), frequency-coded MR signals (S1, S2) from the examination volume are recorded. The position of the medical instrument is determined by analyzing the differences between the recorded MR signals (S1, S2).

Abstract: A guidewire (100) for use with interventional magnetic resonance imaging has a guidewire body (102) having a distal end and a proximal end and reserving a space therein, a dipole antenna (108) disposed in the space reserved within the guidewire body, the dipole antenna being adapted to be electrically connected to a signal processing system through a first signal channel (110) through the proximal end of the guidewire body, and a loop antenna (112) disposed in the space reserved within the guidewire body toward the distal end of the guidewire body, the loop antenna (112) being adapted to be electrically connected to the signal processing system through a second signal channel (114) through the proximal end of the guidewire body. The dipole antenna and the loop antenna are each constructed to receive magnetic resonance imaging signals independently of each other and to transmit received signals through the first and second signal channels, respectively, to be received by the signal processing system.

Abstract: One or more markers or sensors are positioned in the vasculature of a patient to facilitate determining the location, configuration, and/or orientation of a vessel or certain aspects thereof (e.g., a branch vessel), determining the location, configuration and/or orientation of a endovascular devices prior to and during prosthesis deployment as well as the relative position of portions of the vasculature and devices, generating an image of a virtual model of a portion of one or more vessels (e.g., branch vessels) or devices, and/or formation of one or more openings in a tubular prosthesis in situ to allow branch vessel perfusion when the prosthesis is placed over one or more branch vessels in a patient (e.g., when an aortic abdominal artery stent-graft is fixed to the aorta superior to the renal artery ostia).

Abstract: A catheter comprises an elongate body extending along a first longitudinal axis and having an outermost radial surface; a coil wound in a substantially cylindrical shape and extending along a second longitudinal axis that is coincident with the first longitudinal axis. At least a portion of the coil is proximate to the outermost radial surface of the elongate body.

Abstract: A magnetic induction (MI) repeater includes first and second coils configured to have the same resonance frequency and to be substantially isolated from one another, and an amplifier connected to the first and second coils and configured to receive a signal induced in the first coil by a first magnetic field and output, via the second coil, a second magnetic field based on the signal, wherein the second magnetic field is amplified relative to the first magnetic field.

Abstract: A body-insertable device including a resonance circuit for emitting a resonance magnetic field by being induced by a drive magnetic field received from the outside. An external device for deriving position information of the resonance circuit by using a detection signal of detected resonance magnetic field. The external device includes a drive coil driving unit for outputting a drive signal having a predetermined frequency, a drive coil for receiving the output drive signal and generating the drive magnetic field, and a drive magnetic field generation control unit for calculating an amplitude value of the drive signal by using a current amplitude value of the drive signal, detecting a degree of stability indicating whether a sharp change occurs in the drive magnetic field based on the calculated amplitude value, and controlling the deriving of a position information based on the detected degree of stability in the drive magnetic field.

Abstract: A waveguide antenna assembly for a magnetic resonance tomography apparatus, particularly a waveguide antenna assembly that can be detuned for an operation with local coils, is composed of multiple metal surfaces connected by diodes respectively located between the metal surfaces. Only when the diodes are through-connected between these metal surfaces are the surfaces connected with one another in terms of RF signals via these diodes, so the assembly operates as a waveguide antenna. When the diodes are disabled between these metal surfaces, the surfaces are unconnected with one another for RF signals.

Abstract: A system and method of tracking a medical device and generating an image of a target area. The medical device includes a tracking device to create an imaging field-of-view that extends beyond the tip of the medical device while allowing the tip of the medical device to be visualized. The medical device further includes an imaging/visualization device to create an imaging field from the point of view of the medical device. A voltage standing wave suppression device is formed on the exterior surface of the medical device to prevent the formation of voltage standing waves and localized tissue heating. The voltage standing wave suppression device includes two cable traps spaced apart from one another with each cable trap being formed of a closely packed coiled region of a conductor extending the length of the medical device.

Abstract: An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.

Abstract: An integrated catheter placement system for accurately placing a catheter within a patient'vasculature is disclosed. In one embodiment, the integrated system comprises a system console, a tip location sensor for temporary placement on the patient's chest, and an ultrasound probe. The tip location sensor senses a magnetic field of a stylet disposed in a lumen of the catheter when the catheter is disposed in the vasculature. The ultrasound probe ultrasonically images a portion of the vasculature prior to intravascular introduction of the catheter. The ultrasound probe includes user input controls for controlling use of the ultrasound probe in an ultrasound mode and use of the tip location sensor in a tip location mode. In another embodiment, ECG signal-based catheter tip guidance is included in the integrated system to enable guidance of the catheter tip to a desired position with respect to a node of the patient's heart.

Abstract: An MRI-compatible catheter includes an elongated flexible shaft having opposite distal and proximal end portions. A handle is attached to the proximal end portion and includes an actuator in communication with the shaft distal end portion that is configured to articulate the shaft distal end portion. The distal end portion of the shaft may include an ablation tip and includes at least one RF tracking coil positioned adjacent the ablation tip that is electrically connected to an MRI scanner. The at least one RF tracking coil is electrically connected to a circuit that reduces coupling when the at least one RF tracking coil is exposed to an MRI environment. Each RF tracking coil is a 1-10 turn solenoid coil, and has a length along the longitudinal direction of the catheter of between about 0.25 mm and about 4 mm.

Abstract: A system includes a component that updates a registration between an image space coordinate system and an interventional space coordinate system. The registration update is based on interventional device position information within a patient obtained from intermediate image data indicative of the interventional device location and a position sensor that is located on an interventional device within the patient.

Abstract: An interconnect for an RF detector coil comprises a substrate comprising strip of insulating material, a conducting layer formed on a first side of the substrate, and a ground layer formed on a second side of the substrate. At least one of the layers has a periodic pattern so that the conducting layer alternates along its length between capacitive regions which are opposite regions of the ground layer, and non-capacitive regions.

Abstract: A magnetic resonance imaging (MRI) system includes an interventional instrument and a switched, segmented transmission (Tx) line which ensures safety during an MRI protocol while the interventional instrument is located in the system. The transmission line includes at least two electrically conductive Tx line segments separated by a non-conductive gap. An electrically conductive bridge, having an open and a closed state, and a parallel connected impedance bridge, having a known impedance which suppresses RF current between the line segments, bridge the non-conductive gap. A measurement unit measures the impedance across the Tx line while the conductive bridges are open. The line segments are verified to be decoupled if the measured impedance of the line is substantially equal to that of the impedance bridge.

Abstract: A catheter device for deploying a local magnetic resonance imaging (MRI) coil is provided. The catheter device includes an outer catheter shaft having a lumen extending from a proximal end to a distal end and an inner catheter shaft having a lumen extending from a proximal end to a distal end. The outer and inner catheter shafts are movably engaged such that one can move relative to the other. A plurality of non-metallic filaments are coupled on one end to the outer catheter shaft and coupled on another end to the inner catheter shaft. The plurality of non-metallic filaments are intertwined to form a braid, to which a local MRI coil is coupled. The local MRI coil is configured to have a circular shape when the braid is in a deployed position. Additionally, motion tracking coils can be coupled to the braid to provide motion tracking information for motion compensation.

Abstract: A tracking device configured to be coupled to an interventional instrument and tracked by a magnetic resonance imaging system is provided. The tracking device includes, for example, paramagnetic and diamagnetic components that form first and second tracking members. When the tracking device is adjusted into a first arrangement, the tracking device will produce a local magnetic field in the presence of the magnetic field of an MRI system that is measurable by the MRI system. However, when the tracking device is adjusted into a second arrangement, the local magnetic field produced by the tracking device is reduced relative to the first arrangement, wherein the reduced local magnetic field produces substantially no magnetic field disturbances detectable by the MRI system. Images may be acquired of a patient in which the tracking device has been introduced and, using a numerical fitting method, an accurate location of the tracking device can be determined.

Abstract: Elongate intrabody MRI-antenna probes include opposing distal and proximal portions. The distal portion includes at least one multi-turn conductor arranged as a stack of substantially flat loops, each with a substantially rectangular elongate shape. A flat loop can reside on each of a plurality of adjacent vertically stacked substantially planar layers, the flat loops cooperate to define a MRI receive antenna.

Abstract: An interventional device configured for placement in or near an internal organ or tissue is provided. The interventional device includes a reference portion having three or more sensor elements. In one implementation, the interventional device and associated sensor elements provide dynamic referencing of the internal organ, tissue or associated vasculature after registration of the sensor data with images and/or volumetric representations of the internal organ or tissue.

Abstract: Packaged systems for implanting a marker in a patient and methods for manufacturing and using such systems. In one embodiment, a packaged system comprises an introducer having a cannula and a stylet configured to be received in the cannula, a marker in the cannula, and a package having a sterile compartment. The marker can have a casing configured to be implanted in a patient and a resonating circuit in the casing. The resonating circuit can comprise a coil configured to wirelessly transmit a target signal in response to a wirelessly transmitted excitation signal. The introducer is contained within the sterile compartment. In another embodiment, the marker is not loaded in the introducer within the compartment of the package.

Abstract: The present invention is directed to a device and method for opening obstructed body internal passages and for sensing and characterizing tissues and substances being in contact with the device of the invention. In general, the device of the present invention comprises a catheter tube capable of inducing vibrations in a guidewire contained therein, wherein said vibrations of the guidewire are utilized for opening a passage through an occlusion. The in-vivo vibrations may be induced by means of a magnetic field actuating means (5) and a guidewire (2) comprising magnetic coupling means (3), or by means of transducers, which may be also used for the sensing.

Abstract: A magnetic resonance probe may include a plurality of center conductors, at least some center conductors including a conductive core and an insulator disposed at least partially about the core along at least a portion of the core, a first dielectric layer disposed at least partially about the plurality of center conductors in a proximal portion of the probe, an outer conductive layer at least partially disposed about the first dielectric layer, and a plurality of electrodes, at least one electrode being coupled to one of the center conductors and disposed at least partly on a probe surface.