Detectable Material Placed In Body Patents (Class 600/431)
  • Patent number: 12039723
    Abstract: A method for enhancing a near-infrared fluorescence image includes providing a NIR fluorescence image produced by detecting light in the NIR-I or NIR-IIa windows emitted by fluorophores; and inputting the NIR fluorescence image to a convolutional neural network to produce as output a translated image, where the convolutional neural network is trained using a set of NIR-I or NIR-IIa fluorescence images and a set of NIR-IIb fluorescence images. Preferably, the convolutional neural network is a U-Net.
    Type: Grant
    Filed: September 11, 2021
    Date of Patent: July 16, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hongjie Dai, Zhuoran Ma
  • Patent number: 12029600
    Abstract: A method and system for generating material decomposition images from plural-energy x-ray based imaging, the method comprising: modelling spatial relationships and spectral relationships among the plurality of images by learning features from the plurality of images in combination and one or more of the plurality of images individually with a deep learning neural network; generating one or more basis material images employing the spatial relationships and the spectral relationships; and generating one or more material specific or material decomposition images from the basis material images. The neural network has an encoder-decoder structure and includes a plurality of encoder branches; each of one or more of the plurality of encoder branches encodes two or more images of the plurality of images in combination; and each of one or more of the plurality of encoder branches encodes a respective individual image of the plurality of images.
    Type: Grant
    Filed: June 16, 2023
    Date of Patent: July 9, 2024
    Assignee: CURVEBEAM AI LIMITED
    Inventor: Yu Peng
  • Patent number: 12033310
    Abstract: An image processing apparatus includes at least one processor. The processor is configured to execute processing of acquiring a first image as a radiographic image including an image of a subject generated by radioscopy for continuously irradiating the subject with radiation to perform imaging, acquiring a second image different from the radiographic image including the image of the subject before acquiring the first image, specifying a subject region as a region where the image of the subject is formed in the first image, based on the second image, and executing image processing of enhancing contrast of the specified subject region on the first image and outputting the first image after the image processing.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: July 9, 2024
    Assignee: FUJIFILM CORPORATION
    Inventor: Kouichi Kitano
  • Patent number: 12025441
    Abstract: A system uses range and Doppler velocity measurements from a lidar system and images from a video system to estimate a six degree-of-freedom trajectory of a target. The system estimates this trajectory in two stages: a first stage in which the range and Doppler measurements from the lidar system along with various feature measurements obtained from the images from the video system are used to estimate first stage motion aspects of the target (i.e., the trajectory of the target); and a second stage in which the images from the video system and the first stage motion aspects of the target are used to estimate second stage motion aspects of the target. Once the second stage motion aspects of the target are estimated, a three-dimensional image of the target may be generated.
    Type: Grant
    Filed: July 4, 2022
    Date of Patent: July 2, 2024
    Assignee: Aeva, Inc.
    Inventors: Richard L. Sebastian, Anatoley T. Zheleznyak
  • Patent number: 12025483
    Abstract: Method and systems for determining acceptance criteria for identification of occluding particles in a lumen of a device are provided. The methods and systems can be used in methods of identifying an occluded device in an inspection method. The acceptance criteria can be calculated based on mass flow measurements of an occluded representative device.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: July 2, 2024
    Assignee: INNOVATIVE HEALTH
    Inventors: Aaron J. Fowler, Blessan C. Joseph, Rafal Chudzik
  • Patent number: 12016738
    Abstract: An illustrative surgical system may access a plurality of images captured outside a structure within a patient; detect a difference between spectral reflectances of scenes captured in the plurality of images; and identify, based on the detected difference between the spectral reflectances of the scenes captured in the plurality of images, pixels in at least one of the plurality of images that correspond to structure tissue of the structure.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: June 25, 2024
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Jeffrey M. DiCarlo, Ian E. McDowall, Jonathan M. Sorger
  • Patent number: 12016624
    Abstract: A thermal accelerant is delivered to a tissue site and localized to modulate the shape, extent or other characteristic of RF or microwave-induced hyperthermic tissue ablation. The accelerant may be provided via an image-guided hand piece or via a lumen added to a microwave antenna, and promotes faster heating, more complete ablation and/or a more extensive treatment region to reduce recurrence of treated cancers, overcoming natural limitations, variations in tissue response and drop-off or thermal loss away from the antenna. The accelerant is delivered as a viscous but heat sensitive fluid, and is fixed in place to provide regions of preferential absorption or heating. Shorter exposure times to heat the far field may allow survival of vulnerable tissue such as vessels, and multiple antennae may be used for effective treatment of irregular or large tumors.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: June 25, 2024
    Assignees: Rhode Island Hospital, Brown University
    Inventors: William Keun Chan Park, Damian E. Dupuy
  • Patent number: 12020047
    Abstract: A virtualization infrastructure control device (10) includes: a monitoring unit (13) for acquiring load information regarding a resource; a scaling control unit (11) for determining, based on the load information, whether or not to perform scaling and calculating a resource amount required for the scaling; and a resource delivery control unit (12) for converting the resource amount required for the scaling to a change number for the number of allocated CPUs regarding a CPU core that is a resource allocated to VM-by-VM, selecting the change number of CPU cores that are to be subjected to the scaling, and transmitting, to a compute, resource change instruction information including information regarding the selected CPU cores whose allocation is to be changed.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 25, 2024
    Assignee: Nippon Telegraph and Telephone Corporation
    Inventor: Eriko Iwasa
  • Patent number: 12017092
    Abstract: A method and/or system are provided for improving kidney function and/or increasing Glomerular Filtration Rate (GFR) of the renal system, by applying acoustic and/or ultrasonic energy to one or more of the kidneys. The method suggests either focused or non-focused (or combined) energy delivery, optionally in a noninvasive approach, which could also be implemented invasively and/or by implantable device. Potential applications of this technique, include, but are not restricted to, treatment of renal disorders such as CKD (Chronic Kidney Disease) and/or AKI (Acute Kidney Injury), short term or long term intervention in kidney function for therapeutic or diagnostic purposes, modifying urine output in heart failure, modulating blood volume and/or pressure, and modulating clearance of compounds in the blood are typically difficult to extract from the kidneys, such as iodine, other imaging contrast media, and similar compounds.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: June 25, 2024
    Assignee: MDSG Innovation Ltd.
    Inventors: Benny Rousso, Lior Eshel, Assaf Erell, Naama Winetraub
  • Patent number: 11963764
    Abstract: A flexible oximeter device for measuring pulse and blood oxygen saturation in tissue includes a first array of first light emitting elements that emit red light, a second array of second light emitting elements that emit green light or near-infrared (NIR) light and an array of sensor elements arranged on at least one flexible substrate. Each sensor element is configured to detect red and green or NIR light, and to output a signal representing an amount of red or green or NIR light detected. The first and second arrays and the array of sensor elements form a plurality of interleaved measurement pixels, each pixel comprising one of the first light emitting elements and a corresponding sensor element, and one of the second light emitting elements and a different corresponding sensor element.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: April 23, 2024
    Assignee: The Regents of the University of California
    Inventors: Yasser Khan, Donggeon Han, Adrien Pierre, Jonathan Ting, Xingchun Wang, Claire Meyer Lochner, Ana Arias
  • Patent number: 11957936
    Abstract: A system for transcranial magnetic resonance (MR)-guided focused ultrasound and method of using transcranial MR-guided focused ultrasound are disclosed. The system includes a transcranial ultrasound transducer configured to apply ultrasound radiation to a patient's head. The system also includes an antenna that reflects radio frequency (RF) waves. The antenna is configured to be positioned between the transducer and the patient's head. The antenna and at least a portion of the patient's head are surrounded by a fluid. Embodiments foster improved MR image quality scans of the patient's head when the transducer is filled with the fluid.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: April 16, 2024
    Assignee: Vanderbilt University
    Inventors: Xinqiang Yan, William A. Grissom
  • Patent number: 11957565
    Abstract: A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.
    Type: Grant
    Filed: June 9, 2023
    Date of Patent: April 16, 2024
    Assignee: CONMED Corporation
    Inventors: Kevin A. Rocco, Bhavana Mohanraj, Jeffrey Ott, Justin Bendigo, Jacob Edward Komenda, Mark Theodore Aronson, Andrew James Carter
  • Patent number: 11950921
    Abstract: The present invention relates to a portable device for measuring skin condition and a skin condition diagnosis and management system using same. The device for measuring skin condition according to the present invention is a portable type of device that can be easily carried by a user, and when an image of a user's face is captured, can acquire a clear image of the entire face of the user by effectively controlling the user's face position.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: April 9, 2024
    Assignee: Lululab Inc.
    Inventors: Sang Wook Yoo, Yong Joon Choe, Sijun Roh
  • Patent number: 11951283
    Abstract: A hand-control device for controlling the operation of an injection system is described herein. The hand-control device includes one or more input components that receive input to control various operations of the injection system, including commanding the injection to perform a particular operation, changing an operational aspect of the injection system, and selecting an operational mode for the injection system. A communication unit of the hand-control device generates and conveys a signal for the injection system, and receives a command signal from the injection system. An output component outputs an indication, such as a light emission, a sound, or haptic feedback, in response to receiving the command signal. In some instances, this indication acts as a confirmation or failure of the intended input.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: April 9, 2024
    Inventors: Caleb D. Tkach, Spencer Fodness-Bondhus, Blaise D. Porter
  • Patent number: 11937913
    Abstract: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: March 26, 2024
    Assignee: Pulmonx Corporation
    Inventors: Srikanth Radhakrishnan, Surag Mantri, Ryan Olivera
  • Patent number: 11911123
    Abstract: A body mountable robot may include a set of stages disposed in a parallel configuration. The body mountable robot may include a set of actuating joints, wherein an actuating joint, of the set of actuating joints, is configured to rotate with respect to a corresponding stage of the set of stages. The body mountable robot may include at least one actuator, wherein the at least one actuator is configured to actuate at least one actuating joint of the set of actuating joints. The body mountable robot may include a set of scissor mechanisms, wherein a scissor mechanism, of the set of scissor mechanisms, that is coupled to the actuating joint, is supported by the corresponding stage, and wherein the scissor mechanism is configured to translate with respect to the corresponding stage.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: February 27, 2024
    Assignee: The Johns Hopkins University
    Inventors: Iulian I. Iordachita, Jin Seob Kim, David Levi, Kevin Cleary, Reza Monfaredi
  • Patent number: 11906425
    Abstract: A phantom design method includes a correction step and a calculation step. In the correction step, an absorption spectrum of a target of spectroscopic measurement by a near infrared spectrometer is corrected based on a refractive index of the target and a refractive index of a resin used as a base material of a phantom to generate a corrected absorption spectrum. In the calculation step, based on an absorption spectrum of the resin and an absorption spectrum of each of N types of dyes, a concentration of each of the N types of dyes to be contained in the base material is calculated such that an absorption spectrum of the phantom constituted by the base material containing the N types of dyes approximates the corrected absorption spectrum in a predetermined wavelength range of a near infrared region.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: February 20, 2024
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Kenji Yoshimoto, Yukio Ueda
  • Patent number: 11894139
    Abstract: Described herein are systems, media, and methods for assessing an individual by generating a classification or regression based on input data comprising metabolite information, protein information, nucleic acid information, non-molecular information, or any combination thereof.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: February 6, 2024
    Assignee: PatientsLikeMe LLC
    Inventors: Aaron Van Hooser, Renee Deehan-Kenney
  • Patent number: 11883099
    Abstract: Methods and systems for identifying CNV membranes and vasculature in images obtained using noninvasive imaging techniques are described. An example method includes generating, by a first model based on at least one image of a retina of a subject, a membrane mask indicating a location of a CNV membrane in the retina. The method further includes generating, by a second model based on the membrane mask and the at least one image, a vasculature mask of the retina of the subject, the vasculature mask indicating CNV vascularization in the retina.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: January 30, 2024
    Assignee: Oregon Health & Science University
    Inventors: Yali Jia, Jie Wang
  • Patent number: 11871895
    Abstract: The present invention provides a targeted nanoplex platform for in vivo imaging and theranostic imaging of cancer to simultaneously provide non-invasive assessment of tumor burden and cancer-selective treatments.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: January 16, 2024
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Ming Li, Ishan Barman, Martin Pomper, Sangeeta Ray
  • Patent number: 11871960
    Abstract: Methods for performing certain medical procedures wherein a steerable endoluminal punch is used to not only gain access but to create a channel or punch through tissue, thus facilitating follow-up therapeutic procedures. The distal end of the steerable endoluminal punch is controllably articulated by the operator using a control device at the proximal end.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: January 16, 2024
    Assignee: Indian Wells Medical, Inc.
    Inventors: Jay A Lenker, Peter van der Sluis
  • Patent number: 11874221
    Abstract: Methods and apparatus for analyzing optical measurements to determine whether a liquid includes dissolved oxygen, to determine a predicted concentration of the dissolved oxygen in the liquid, and/or to determine additional or alternative feature(s) related to dissolved oxygen in the liquid. An optical source can be controlled to emit optical radiation into a container that contains the liquid. The optical source can be located outside of the container, and the optical radiation includes (e.g., is restricted to) radiation that conforms to a dissolved oxygen absorption band. The optical radiation can be pulsed or can be periodically intensity modulated. A photodetector, located outside of the container but in optical communication with the interior of the container, can generate the optical measurements used in the analysis.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: January 16, 2024
    Assignee: YOKOGAWA ELECTRIC CORPORATION
    Inventor: Anatoliy A. Kosterev
  • Patent number: 11872092
    Abstract: A tissue implantation device comprises a capsule; and a population of ultrasound-switchable fluorophores incorporated in the capsule. A method of imaging a tissue implantation device in a biological environment comprises disposing the tissue implantation device in a biological environment, the population of ultrasound-switchable fluorophores having a switching threshold in the biological environment; exposing the biological environment to an ultrasound beam to form an activation region within the biological environment; switching the ultrasound-switchable fluorophores in the activation region from an off state to an on state; exciting the ultrasound-switchable fluorophores in the activation region with a beam of electromagnetic radiation; and detecting light emitted by the ultrasound-switchable fluorophores.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: January 16, 2024
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Baohong Yuan
  • Patent number: 11857375
    Abstract: A medical imaging system acquires a first medical image of a breast as an object using a first imaging apparatus in a state in which the breast is fixed, captures a second medical image of the breast as the object using a second imaging apparatus having a different imaging principle from the first imaging apparatus in a state in which the fixation of the breast is maintained, sets a period for which the second medical image is captured and a period for which the first medical image is analyzed so as to at least partially overlap each other in a case in which the first medical image is analyzed to detect a region of interest, and outputs positional information such that a region-of-interest image having the region of interest as a main object is captured in a case in which the region of interest has been detected.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: January 2, 2024
    Assignee: FUJIFILM Corporation
    Inventors: Riko Koshino, Shun Hotta
  • Patent number: 11861822
    Abstract: An image recognition device and method retrieve information on a marker. The marker encodes information identifying an asset by encoding the information in a binary pattern as recesses and non-recesses in the marker. The image recognition is performed by imaging the marker, mapping contrast in the image, identifying variations in the contrast, creating a mesh overlaying the image, identifying the present or absence of recesses from the mesh, and reading the binary pattern represented by the recesses in the marker.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: January 2, 2024
    Assignee: SAUDI ARABIAN OIL COMPANY
    Inventors: Enrico Bovero, Dana Abdullatif
  • Patent number: 11858181
    Abstract: An ultrasound-detectable polymeric device that offers superior visibility of the body of the device and decreased ultrasound angle dependence through the use of microcavities and methods of manufacturing thereof is disclosed. These microcavities enable superior ultrasound visualization due to diffuse reflection of sound waves when compared to solid polymeric objects, ensuring that a strong signal is received at the source of the ultrasound transducer and providing strong image contrast throughout the entire cross-section of the implant that is also robust to variable angles of insonation.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: January 2, 2024
    Assignee: Sonavex, Inc.
    Inventors: Devin O'Brien-Coon, David Narrow
  • Patent number: 11857164
    Abstract: The invention relates to a method, an image processor (26) and a medical observation device (1), such as a microscope or endoscope, for observing an object (4) containing a bolus of at least one fluorophore (12). The object (4) is preferably live tissue comprising several types (16, 18, 20) of tissue. According to the method, a set (34) of component signals (36) is provided. Each component signal (36) represents a fluorescence intensity development of the fluorophore (12) over time in a different type of tissue. A time series (8) of input frames (10) is accessed, one input frame (10) after the other. The input frames (10) represent electronically coded still images of the object (4) at subsequent time. Each input frame (10) contains at least one observation area (22) comprising at least one pixel (23).
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: January 2, 2024
    Assignee: Leica Instruments (Singapore) Pte. Ltd.
    Inventor: George Themelis
  • Patent number: 11847786
    Abstract: A machine learning model is described that is trained without labels to predict a motion field between a pair of images. The trained model can be applied to a distinguished pair of images to predict a motion field between the distinguished pair of images.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: December 19, 2023
    Assignee: ECHONOUS, INC.
    Inventors: Allen Lu, Babajide Ayinde
  • Patent number: 11841351
    Abstract: A response factor that is a signal strength ratio with respect to a reference compound for various compounds is previously stored in a response factor storage (22). When an operator instructs to estimate an analysis limit value, a measurement unit (1) performs GC-MS analysis on a sample containing the reference compound a plurality of times under control of an analysis controller (3). A signal strength calculator (23) obtains a signal strength value of the reference compound based on an analysis result of the measurement unit (1), a relative strength calculator (24) calculates a relative standard deviation from the plurality of measured signal strength values, and calculates the relative standard deviation of a target compound from the response factor of the target compound read from the response factor storage (22).
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: December 12, 2023
    Assignee: SHIMADZU CORPORATION
    Inventor: Yukihiko Kudo
  • Patent number: 11839449
    Abstract: Methods and systems of monitoring and controlling thermal therapy treatments. One method includes determining, with an electronic processor, a propagation constant for a plurality of waveports. The method also includes modeling an object within an imaging cavity using a sparse mesh model. The method also includes determining a simulated impedance of the object based on the model of the object. The method also includes calibrating the simulated impedance with a theoretical impedance numerically calculated for the object. The method also includes determining a distribution of an electric field and a distribution of a magnetic field for a mode in a conformal modeled waveport based on the calibrated impedance and the model of the object. The method also includes exciting the plurality of waveports to generate the determined distribution of the electric field and the distribution of the magnetic field.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: December 12, 2023
    Assignee: University of Southern California
    Inventors: John P. Stang, Mark S. Haynes, Mahta Moghaddam, Guanbo Chen
  • Patent number: 11839511
    Abstract: An ultrasound image tracking completeness system includes an ultrasound imaging probe that acquires images during an examination, an imaging probe sensor coupled to the ultrasound imaging probe and that tracks a position and an orientation of the ultrasound imaging probe, and a display to display images acquired by the ultrasound imaging probe. The system also includes a processor programmed to calculate a probe speed threshold at which the ultrasound imaging probe may be moved while acquiring images during the examination, track the position and orientation of the ultrasound imaging probe during the examination by monitoring the imaging probe sensor, determine a movement speed of the ultrasound imaging probe during the examination, and if the movement speed of the ultrasound imaging probe exceeds the probe speed threshold, issue a warning to an operator.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: December 12, 2023
    Assignee: Metritrack, Inc.
    Inventors: Calin Caluser, Guang Yang
  • Patent number: 11836925
    Abstract: A system for image segmentation is provided. The system may obtain a target image including an ROI, and segment a preliminary region representative of the ROI from the target image using a first ROI segmentation model corresponding to a first image resolution. The system may segment a target region representative of the ROI from the preliminary region using a second ROI segmentation model corresponding to a second image resolution. At least one model of the first and second ROI segmentation models may at least include a first convolutional layer and a second convolutional layer downstream to the first convolutional layer. A count of input channels of the first convolutional layer may be greater than a count of output channels of the first convolutional layer, and a count of input channels of the second convolutional layer may be smaller than a count of output channels of the second convolutional layer.
    Type: Grant
    Filed: May 22, 2022
    Date of Patent: December 5, 2023
    Assignee: SHANGHAI UNITED IMAGING INTELLIGENCE CO., LTD.
    Inventors: Miaofei Han, Yaozong Gao, Yu Zhang, Yiqiang Zhan
  • Patent number: 11832924
    Abstract: Methods for dynamically evaluating blood flow are provided. The method may include injecting Indocyanine Green (ICG) into the bloodstream of a patient, such that the ICG perfuses into a tissue of the patient. ICG images of the tissue may be recorded and stored, such that a user may select a range of stored ICG images. Data indicative of the selected range of stored ICG images is automatically normalized and background-filtering, and a dynamic representation of the ICG perfusion may be generated as a function of time based on the normalized and filtered data. As such, a clinical decision may be made based on the dynamic representation of the ICG perfusion.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: December 5, 2023
    Assignee: The Regents of the University of California
    Inventors: Shanglei Liu, Santiago Horgan, David Owens
  • Patent number: 11836920
    Abstract: An apparatus for classifying a brain tissue area as functional or non-functional by a stimulation of the brain includes a receiver unit for receiving information about a performed stimulation, a recording device for recording images that represent the brain tissue area, a detection unit for detecting a change in perfusion in the brain tissue area, and a classification unit configured to determine with the information whether there is a correlation between the performed stimulation and the detected change in perfusion, and to classify the brain tissue area as functional or as non-functional. The recording device is an endomicroscope for recording endomicroscopic images of the brain tissue area with a spatial resolution better than 20 ?m and a frame rate of at least 0.4 frames per second. The detection unit is configured to detect a change in perfusion based on the positions of certain tissue structures in the recorded images.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: December 5, 2023
    Assignee: Carl Zeiss Meditec AG
    Inventors: Christoph Hauger, Stefan Saur, Gerald Panitz
  • Patent number: 11826553
    Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: November 28, 2023
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, David Griffiths
  • Patent number: 11808902
    Abstract: An imaging system includes a first mask unit having a hollow cavity surrounding a rotational axis. The first mask unit is characterized by a first pattern encoded on its surface. The first pattern defines a height along an axial direction and includes a respective plurality of elements with at least one open element and at least one blocking element in each of the axial direction and the circumferential direction. A detector is configured to receive radiation data from at least one source such that one of the detector and the source is located inside the hollow cavity and another is located outside the hollow cavity. The first mask unit is configured to move relative to the rotational axis in at least one of the axial and circumferential direction until the first pattern is recorded in 360 degrees. A second mask unit may be positioned around the first mask unit.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: November 7, 2023
    Inventors: Steven Brown, Kevin Moran
  • Patent number: 11806106
    Abstract: A probe for use in an anatomical region of a patient. The probe can optionally include: a proximal portion; an insertion portion and a magnetizable element. The insertion portion can be coupled to the proximal portion and can extend distally thereof. The insertion portion can have an elongated extent and a longitudinal axis. The insertion portion can include a flexible section. The magnetizable element can be positioned at a distal end portion of the insertion portion and can be configured for use within the anatomical region to produce a magnetic force between the magnetizable element and an extracorporeal magnetizable element that can direct the distal end portion of the probe to a desired location within the anatomic region.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: November 7, 2023
    Assignee: Gyrus ACMI, Inc.
    Inventors: Hiroyuki Kojo, Tara Hendrzak
  • Patent number: 11801371
    Abstract: There is provided a microneedle device comprising a substrate and a plurality of microneedles projecting from the substrate, the substrate being substantially spherical and wherein in use, the microneedle device has three-dimensional movement. There is also provided a method of forming the microneedle device of the present invention.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: October 31, 2023
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Lifeng Kang, Yuanyuan Sun, Duc-Viet Nguyen
  • Patent number: 11801029
    Abstract: A deep learning (DL) convolution neural network (CNN) reduces noise in positron emission tomography (PET) images, and is trained using a range of noise levels for the low-quality images having high noise in the training dataset to produce uniform high-quality images having low noise, independently of the noise level of the input image. The DL-CNN network can be implemented by slicing a three-dimensional (3D) PET image into 2D slices along transaxial, coronal, and sagittal planes, using three separate 2D CNN networks for each respective plane, and averaging the outputs from these three separate 2D CNN networks. Feature-oriented training can be implemented by segmenting each training image into lesion and background regions, and, in the loss function, applying greater weights to voxels in the lesion region. Other medical images (e.g. MRI and CT) can be used to enhance resolution of the PET images and provide partial volume corrections.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: October 31, 2023
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Chung Chan, Jian Zhou, Evren Asma
  • Patent number: 11801115
    Abstract: An imaging system, including a head-mounted display worn by a system operator. A marker defines a plane when attached to a human subject. Optically reflective elements are disposed on the marker and on opposing sides of the plane in a non-symmetrical arrangement with respect to the plane. A memory stores a graphical representation of a tool used in a procedure performed on the human subject, and an image of anatomy of the human subject. A camera attached to the display acquires an image of the marker and the tool. A processor analyzes the image to identify the plane and to identify a side of the plane wherein the camera is located, and to render to the display the image of the anatomy of the human subject with the graphical representation of the tool superimposed thereon from a point of view in the identified side of the plane.
    Type: Grant
    Filed: May 29, 2022
    Date of Patent: October 31, 2023
    Assignee: AUGMEDICS LTD.
    Inventors: Nissan Elimelech, Stuart Wolf, Nitzan Krasney
  • Patent number: 11793891
    Abstract: Compositions comprising a fluorescein component and benoxinate component and the corresponding uses of these compositions are described herein. These compositions have improved storage life and the fluorescein component and/or benoxinate component minimally degrade after 12 to 18 months of storage.
    Type: Grant
    Filed: March 7, 2023
    Date of Patent: October 24, 2023
    Assignee: OPUS LIFE SCIENCES, LLC
    Inventors: Patrick H. Witham, William Stringer
  • Patent number: 11794177
    Abstract: A composition, method, and article of manufacture are disclosed. The composition includes a silica particle with light upconversion molecules bound to its surface. The method includes obtaining silica particles and light upconversion molecules having sidechains with reactive functional groups. The method further includes binding the light upconversion molecules to surfaces of the silica particles. The article of manufacture includes the composition.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: October 24, 2023
    Assignee: International Business Machines Corporation
    Inventors: Jason T. Wertz, Brandon M. Kobilka, Sarah K. Czaplewski-Campbell, Eric J. Campbell
  • Patent number: 11788963
    Abstract: Minimizing image sensor input/output pads in a pulsed fluorescence imaging system is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a plurality of bidirectional pads comprising an output state for issuing data and an input state for receiving data. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 770 nm to about 790 nm and/or from about 795 nm to about 815 nm.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: October 17, 2023
    Assignee: Cilag GmbH International
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 11786201
    Abstract: A method and system for generating material decomposition images from plural-energy x-ray based imaging, the method comprising: modelling spatial relationships and spectral relationships among the plurality of images by learning features from the plurality of images in combination and one or more of the plurality of images individually with a deep learning neural network; generating one or more basis material images employing the spatial relationships and the spectral relationships; and generating one or more material specific or material decomposition images from the basis material images. The neural network has an encoder-decoder structure and includes a plurality of encoder branches; each of one or more of the plurality of encoder branches encodes two or more images of the plurality of images in combination; and each of one or more of the plurality of encoder branches encodes a respective individual image of the plurality of images.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: October 17, 2023
    Assignee: CURVEBEAM AI LIMITED
    Inventor: Yu Peng
  • Patent number: 11786301
    Abstract: The present disclosure provides electroporation systems and methods of energizing a catheter for delivering electroporation. A catheter for delivering electroporation includes a distal section and an electrode assembly. The distal section is configured to be positioned in a vein within a body. The vein defines a central axis. The electrode assembly is coupled to the distal section and includes a structure and a plurality of electrodes distributed thereabout. The structure is configured to at least partially contact the vein. Each of the electrodes is configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein.
    Type: Grant
    Filed: October 12, 2022
    Date of Patent: October 17, 2023
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventor: Eric Olson
  • Patent number: 11779299
    Abstract: A control device including: wherein the processor controls a mammography apparatus that a breast, with radiation from a radiation source to capture a radiographic image of the breast such that normal imaging which emits the radiation with first energy from an irradiation position where an irradiation angle is 0 degrees to capture a normal radiographic image and tomosynthesis imaging which emits the radiation with either the first energy or second energy higher than the first energy at each of a plurality of irradiation positions having different irradiation angles and emits the radiation with the second energy at the irradiation position where the irradiation angle is 0 degrees to capture a plurality of low-energy projection images and a plurality of high-energy projection images are performed in a state in which the breast is compressed by the compression member.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: October 10, 2023
    Assignee: FUJIFILM CORPORATION
    Inventors: Hiroki Nakayama, Tomoki Inoue
  • Patent number: 11779297
    Abstract: A control device includes a processor that controls a mammography apparatus that irradiates a breast with radiation to capture a radiographic image of the breast such that the radiation with either first energy or second energy higher than the first energy is emitted at each of irradiation positions having different irradiation angles while a radiation source is being moved to capture low-energy projection images with the first energy and high-energy projection images with the second energy, an irradiation time for which the radiation with the second energy is emitted is longer than an irradiation time for which the radiation with the first energy is emitted, and a focus size of the radiation source in a case in which the radiation with the first energy is emitted is larger than a focus size of the radiation source in a case in which the radiation with the second energy is emitted.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: October 10, 2023
    Assignee: FUJIFILM CORPORATION
    Inventors: Hiroki Nakayama, Tomoki Inoue
  • Patent number: 11779431
    Abstract: A marker delivery device includes a handle having a housing, and a cannula positioned in the handle that retractably extends beyond the front end of the housing. A retraction mechanism is mounted to the housing, and has a shear member. The retraction mechanism is coupled to a proximal end of the cannula. The retraction mechanism is configured to store a retraction force, and is configured to facilitate a retraction of the cannula into a chamber of the housing upon an actuation of the retraction mechanism. The shear member has a shear region of reduced cross section dimension. The shear member is configured to be displaced upon the actuation of the retraction mechanism to expose the shear region to the retraction force to shear the shear member at the shear region to enable the retraction and prevent reuse of the marker delivery device.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: October 10, 2023
    Assignee: C. R. Bard, Inc.
    Inventors: Himanshu Ranpura, Chad C. Van Liere
  • Patent number: 11776126
    Abstract: In one embodiment, a patient's brain is evaluated after onset of a stroke by capturing computed tomography angiography (CTA) images of the brain, analyzing the CTA images with a CTA image analysis program to evaluate the patient's brain, and generating results based upon the analysis that provide an assessment of the brain. In some cases, the CTA image analysis program comprises a machine-learning algorithm that has been trained on the results of perfusion imaging analysis.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: October 3, 2023
    Assignee: The Board of Regents, The University of Texas System
    Inventors: Sunil A. Sheth, Luca Giancardo, Sean I. Savitz
  • Patent number: 11759285
    Abstract: A biopsy marker having a spring-loaded anchor. The biopsy marker includes an insertion orientation and an anchored orientation. In the insertion orientation, the biopsy marker is manipulated under force to reduce the lateral span/cross-sectional area of the marker. In the anchored orientation, the biopsy marker is released and free to actively spring into a configuration in which the lateral span/cross-sectional area is greater than the lateral span/cross-sectional area of the biopsy marker when in the insertion orientation. In an embodiment, the spring-loaded anchor is configured to spring about a predefined rotational axis. An embodiment of the biopsy marker may be comprised of a single wire construction.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: September 19, 2023
    Assignee: Med-Genesis, LLC
    Inventor: Frederick Ahari