Abstract: An auto-injector (100) for use with a primed safety syringe (200). The auto-injector comprises: a first detector (312) configured, after activation of the auto-injector, to detect movement of a plunger (206, 222) of the safety syringe to a point on a delivery stroke thereof that is indicative of full dose delivery of a substance from the safety syringe.

Abstract: An assembly for retaining a pressure jacket (134) and a syringe (132) on a fluid injector, the assembly including a base plate (1902) comprising a body (1904); at least a first retaining arm (1910a) and a second retaining arm (1910b) operatively mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured for abutting a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operatively connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.

Abstract: An echogenic balloon dilation catheter and a balloon thereof. The balloon includes a balloon body, a balloon cone at each side of the balloon body, and a balloon tip extending from the balloon cone and fixed to the catheter, the balloon body and the balloon cone being formed of a plurality of polymer layers in a radial direction of the balloon. The balloon may be of enhanced echogenicity using a variety of disclosed techniques.

Abstract: A drug delivery device for delivering a medicament includes a housing arranged to contain a container, a receiver coil, and an energy storage unit. The receiver coil is arranged to receive energy from a transmitter coil by electromagnetic induction. The energy storage unit is arranged to be charged by at least a portion of the energy received by the receiver coil. At least a portion of the energy received by the receiver coil is converted to heat energy. The receiver coil is arranged in the drug delivery device to transfer the heat energy to the container to heat medicament contained in the container. A system comprising the drug delivery device is also disclosed.

Abstract: A method for dynamic pressure control during a multiphase injection is described wherein the pressures of fluids in the various reservoirs of a fluid delivery system are controlled to provide desired fluid delivery parameters. The methods include advancing the first drive member to expel the first fluid from the first reservoir into a conduit, wherein the fluid is pressurized to a first fluid pressure; measuring the first fluid pressure to provide a target value; while the second reservoir is in fluid isolation from the conduit, advancing or retracting the second drive member to increase or decrease the fluid pressure of the second fluid in the second reservoir to the target value; placing the second reservoir in fluid communication with the conduit; and advancing the second drive member to expel the second fluid from the second reservoir into the conduit.

Abstract: Described is a metering pump that may be used to meter volumes of sample in a chromatography system. The metering pump has a modular configuration that allows for separation of a head pod from a drive assembly for easy serviceability. The head pod includes a pump head, cartridge housing, seal wash housing and plunger. The drive assembly can be implemented in an inline drive configuration. Alternatively, the drive assembly can be implemented in an offset drive configuration in which a stepper motor is displaced laterally from other drive assembly components but is coupled through a belt and pulley system.

Abstract: Medical systems and methods for making and using medical systems are disclosed. Example medical systems may include an atherectomy system configured to engage and remove plaque from walls in vessels of a vascular system. The atherectomy system may include a drive shaft, a rotational tip coupled to an end of the drive shaft, a drive mechanism coupled to the drive shaft to rotate the rotational tip, and a control unit configured to control operation of the drive mechanism. In some cases, the control unit may include a controller for controlling operation of the drive mechanism based on sensed positions of the drive mechanism. The controller may be configured to send data to a host for analysis, compensate a control signal based on a mode of operation of the drive mechanism, determine if a stall is predicted to occur, and/or perform one or more other functions.

Abstract: A system having a syringe and a connector. A proximal end of an outer housing of the connector is a specially designed female Luer element. A distal end of an outer housing of the connector is configured to connect the syringe to a component of a fluid transfer apparatus. The syringe and the connector are configured to be joined together such that they can be swiveled relative to each other around their common longitudinal axis. Once connected together, any attempt to twist the syringe or connector relative to each other in either a counterclockwise direction or a clockwise direction will result in endless swiveling about their common longitudinal axis. In other words, once the system is connected together, the syringe cannot be disconnected from the connector.

Abstract: A chemical-liquid injection head including a syringe holding unit which holds a syringe in which a piston member is slidably inserted into a cylinder member having a circular cylindrical shape, a piston driving mechanism having a ram member for moving the piston member of the syringe, and a first light emitting portion which emits light with a first color and illuminates the syringe and a second light emitting portion which emits light with a second color and illuminates the syringe. The first light emitting portion and the second light emitting portion, viewed in a posture at the time of use of the injection head, are provided at an upper side of the ram member.

Abstract: An injection system is described that receives, from one or more sensors, a first group of one or more signals indicating a current volume of injection fluid dispensed from a fluid reservoir at a first time. The injection system determines, based on the first group of one or more signals, that a difference between a dispensed volume limit and the current volume of the injection fluid dispensed from the fluid reservoir at the first time is less than a necessary volume of fluid required to complete both a systolic injection phase and a diastolic injection phase. The injection system further, responsive to determining that the difference is less than the necessary volume of fluid required to complete both the systolic injection phase and the diastolic injection phase, controls the injection system to refrain from performing each of the systolic injection phase and the diastolic injection phase.

Abstract: Imaging systems and methods for imaging assisted interventional procedure that receive images of a region of interest, that automatically detect in the images a contrast agent puff as it courses through the region of interest, and that generate a display including a video replay loop of contrast enhanced images based on the automatic detection of the contrast agent puff.

Abstract: An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.

Abstract: An injection apparatus for injecting a medicament into a patient, the injection apparatus has a stationary head and a movable head that is movable with respect to the stationary head. A needle is attached to a needle holder that is held by the movable head and by the stationary head. When the movable head is urged rearwardly, a front edge of the needle moves forwardly with respect to a front face of the movable head.

Abstract: The invention includes a method and a handling system for manipulating and/or for handling piece goods (2) moved one after another in at least one row (1, 1a, 1b) in a transport direction (TR) on a horizontal conveying device (6). In each work cycle, seizing at least one transported piece good (2) from the at least one row (1, 1a, 1b) by at least one handling device (10); spatially separating it from the row (1, 1a, 1b); and bringing it into a specified relative target position and/or target alignment relative to subsequent piece goods (2). After a failure event with an at least a temporary standstill of the horizontal conveying device (6) and/or of the handling device (10), the handling device (10) is initialized, and, after the failure has been remedied, the horizontal conveying device (6) automatically restarts and continues the previously interrupted process.

Abstract: An apparatus and methods for tracking administering of medication by syringes is provided. The apparatus may include a plunger head for a syringe. The plunger head may include a transducer that sends and receives ultrasonic signals. The plunger may also include an antenna and a microcontroller that interfaces with the transducer and the antenna. The plunger may also include a power source that powers the microcontroller and the transducer. The transducer, the antenna, the microcontroller, and the power source may be at least partially encapsulated in an elastomer housing that fits within a barrel of the syringe. The microcontroller may be programmed with instructions to calculate data representative of the quantity of medication dispensed from the barrel and transmit the data to a remote device via the antenna.

Abstract: A medication device with a cartridge or a syringe having a longitudinal axis and containing a medicament, a housing receiving the cartridge or the syringe and having a center axis, and with an RFID device comprising at least one RFID chip with a first antenna, at least one RFID readout unit with a second antenna, wherein the at least one RFID chip is associated with the cartridge or the syringe or the housing and the at least one RFID readout unit is associated accordingly with the housing or the cartridge or the syringe. The first antenna of the at least one RFID chip and the second antenna of the at least one RFID readout unit are each embodied as a coil and aligned so as to be coaxial with one another and with the longitudinal axis as well as with the center axis.

Abstract: A pulmonary access device comprises an elongated shaft having a proximal shaft section, a bendable shaft section, a distal shaft section, and a distal tip. The pulmonary access device further comprises an elongated sheath having a proximal sheath section, a malleable distal sheath section, and working channel. The working channel is configured for slidably receiving the elongated shaft. The pulmonary access device further comprises a handle assembly including a handle body. The handle body is affixed to a proximal end of the elongated shaft. The handle body is removably affixed to a proximal end of the elongated sheath.

Abstract: An adapter for use with a syringe and a power injector includes an outer ring having a first end configured for passage of an end of a syringe having at least one flange. An inner ring is disposed coaxially within the outer ring. The inner ring has a first end including at least one flange slot. A magnet fixed relative to the inner ring such that when the syringe end is disposed in the outer ring and the at least one flange engages the at least one flange slot, rotation of the syringe causes rotation of the inner ring and magnet relative to the outer ring.

Abstract: A drug delivery system for injecting a medicament includes a housing defining a cavity, a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly received within the cavity and configured to drive the stopper within the container, a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position, and a sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system.

Abstract: An apparatus for discharging a dose of a fluid substance to an animal, the apparatus including: a delivery assembly adapted to discharge the dose of the substance to the animal; and a control system operatively associated with the delivery assembly so as to selectively operate the delivery assembly, wherein the control system is adapted to measure the discharge of the fluid substance from the delivery assembly such that the dose is discharged when the delivery assembly is operated.

Abstract: A fluid injector having at least one injector head with a front end configured to releasably receive the at least one syringe is described. The fluid injector further includes at least one pressure jacket releasably associated with the front end of the at least one injector head for securing the at least one syringe during an injection procedure. A connection mechanism releasably connects the at least one pressure jacket to the front end of the at least one injector head. The connection mechanism includes at least one electromagnet.

Abstract: The present invention relates devices capable of continuous and simultaneous expression of components of a multi-part biomedical composition with variable mixing ratios. The device has at least two syringes that contain the inter-reactive components of the multi-part biomedical composition. At least the barrel of the first syringe has a first retention compartment having a cross-sectional area dimension that is larger than the cross-sectional area of a second retention compartment. The first piston has a cross-sectional dimension that matches the inside cross-sectional dimension of the small dimensioned retention compartment, while a ring-shaped gasket is located within the large dimensioned retention compartment and has an outside cross-sectional dimension that matches an interior dimension of the large dimension retention compartment.

Abstract: The present invention relates to the medical field, in particular relates to the practice of percutaneous vertebroplasty where a pair of syringes in the distal extreme of a lengthened hydraulic device, are united by a camera of intermediate connection of larger diameter (pressure exerting body) or modified inverted syringe tube with a bolster, a hydraulic connecting tube of flexible material that transmits the pressure of the smaller diameter manual or impulsion syringe in the proximal extreme of the device toward the intermediate cylindrical larger diameter camera (pressure exerting body), this camera is in an inverted position with regard to the first syringe (fluid control), this intermediate camera has a moving piston longitudinal to the axis of the cylinder that is controlled with the first syringe (manual) and in cooperation with the atmospheric pressure.

Abstract: A rotatable drive mechanism for a drug delivery device may include a lead screw having a distal end, a proximal end, and external threads, a bearing, and a ball screw driver having a threaded aperture wherein the threaded aperture is configured to rotatably engage with the external threads of the lead screw. The mechanism may further include a biasing device disposed between the bearing and the ball screw driver generating an axial drive force, and an activation device configured to release the biasing device and allowing the biasing device to expand from a compressed position to an extended position through which the axial drive force of the biasing device causes the ball screw driver to axially move toward the distal end of the lead screw and rotate the lead screw such that a threaded engagement between the lead screw and the ball screw driver bears the axial drive force.

Abstract: The present invention provides a method for producing a syringe gasket which is improved in liquid drug sealability by forming a minute projection on a circumferential surface of the gasket after demolding the gasket. In a method for producing a syringe gasket including a cylindrical main body (2) made of an elastic material and an inert resin film (3) laminated on a surface of the main body (2), at least one minute projection (5) is formed as extending circumferentially of the gasket on a surface of the inert resin film (3) laminated on the main body (2) by thermal processing using a laser beam.

Abstract: An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.

Abstract: Vision system for measurement of a pitch of graduated marks on a syringe. The vision system may utilize a frequency domain representation of image data to measure the pitch. Furthermore, data processing techniques such as interpolation, windowing, and/or calibration may be utilized in connection with the measurement. In turn, the pitch of the graduated marks may be used in connection with automated filing of the syringe such that the syringe is filled based on and according to the graduated marks on the syringe.

Abstract: Embodiments included herein are directed towards an apparatus that may be used to dispense a fluid. The apparatus may include a housing, wherein the housing includes a first end and a motor, wherein the first end is configured to be coupled to a syringe. The motor may be configured to be operatively connected to a drive tube, wherein at least a portion of the drive tube is configured to extend from and retract into an opening in the first end of the housing in response to the motor. One or more of the motor and the drive tube may be rotationally fixed to the housing. A first end of the drive tube may be configured to be coupled to a piston of the syringe.

Abstract: Automated injection system disclosed in this application advantageously provides physicians with a simplified interface for selecting fluid sources, such as saline, contrast, or a mixture of both, to inject at high pressures. The injector system may comprise a multi-use subassembly, a single-use subassembly, a fitting to fluidly connect the multi-use and single-use subassemblies, a hand held controller, a user interface, and an injector housing.

Abstract: Provided herein are devices for concurrent intravenous infusion of multiple drugs. The device comprises a body with a syringe holding portion and a syringe driving portion, two or more syringes secured therein and a multi-lumen catheter with a plurality of inlet channels and a single outlet channel. Also provided is a method for treating acute myocardial infarction complicated by advanced acute heart failure in a patient. Two or more drugs, such as a beta-blocker and a positive inotropic agent, in prefilled syringes are secured in the device and administered simultaneously into a single vein in a patient without the drugs mixing prior to administration. In addition, a kit is provided that comprises the device and syringes prefilled with a beta-blocker and the positive inotropic agent.

Abstract: The present subject matter includes a cannulated delivery device made of an adapter configured to connect to a syringe; a delivery device tip configured to connect to a dosing chamber; an internal chamber of the cannulated delivery device connecting the adapter and to the delivery device tip, and the internal chamber defining a dose pathway and a system and method of use of the device to increase dosage delivery to a patient while maintaining a sterile fluid pathway.

Abstract: An ultrasound imaging system includes at least one transducer element. The ultrasound imaging system further includes a console with a transducer controller that controls the at least one element, a transducer processor that processes information detected by the at least one element, and a display controller that controls display of the processed information. The ultrasound imaging system further includes a display monitor with a first image display region. The ultrasound imaging system further includes a touch screen keyboard with a second image display region, wherein the display monitor and the touch screen keyboard are separate devices.

Abstract: Contrast administration data that relates to operation of a contrast media injector system (602) may be converted from at least one format (e.g., a CAN-compliant format) to at least one other format (e.g., an HL-7-compliant format) for use by a medical system (600). Data on contrast media prescribed for an imaging operation using an imaging system (690), data on contrast media dispensed from a contrast media storage/dispensing unit (500) for use in this imaging operation, and data on contrast media actually administered/injected by a contrast media injector system (602) for this imaging operation may be stored in a data structure (780). Patient renal function data may be used to control the dispensing of contrast media from the contrast media/storage/dispensing unit (500), to control the operation of the contrast media injector system (602), or both, and may be stored in the data structure (780) as well.

Abstract: The present invention inter alia relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present invention.

Abstract: A controlled delivery drive mechanism includes a drug container having a barrel and a plunger seal; a drive housing within which at least initially partially resides a piston having an interface surface and a drive rack; and a power spring. The piston is configured to contact and axially translate the plunger seal within barrel. The mechanism may be configured to convert rotational movement of a drive pinion to axial translation of the drive rack, or to convert axial force of a linear power spring into torsional motion of a drive pinion. A regulating mechanism meters the drive pinion such that the piston is axially translated at a controlled rate. The drug container may contain a drug fluid within a drug chamber for drug delivery at a controlled rate. The regulating mechanism may be an escapement regulating mechanism. A drug delivery pump includes such controlled delivery drive mechanisms.

Abstract: A vacuum mixing device or system mixes polymethylmethacrylate bone cement from a monomer liquid and a cement powder.

Abstract: A system and method for coordinated and controlled abdominal gas insufflation includes clamp configured to engage an abdominal wall. A needle advancement control is configured to receive a needle and advance the needle toward the clamp to extend into a portion of the abdomen. A feedback device is configured to monitor the needle as it is advanced into the portion of the abdomen of the subject and provide feedback indicating that the needle has pierced the portion the abdomen.

Abstract: The present disclosure concerns a bearing for a piston rod body for a drug delivery device. The bearing has an axis and comprises a first and a second surface which are spaced apart in the direction of the axis and a third surface, wherein the third surface connects the first and the second surface, wherein an opening is provided in each of the first and the third surface, and wherein the opening in the first surface is connected to the opening in the third surface. Further, the present disclosure concerns a piston rod body and a piston rod arrangement comprising said bearing and the piston rod body.

Abstract: A pressure transducer mounting device may include a support member and a pressure transducer holder. In use, the support member may attach to a support surface, such as a housing of a power injection device, while the pressure transducer holder is moveably connected to the support member. The pressure transducer holder may expand open to receive one of a plurality of different sized pressure transducers and bias closed to hold a received one of the plurality of different sized pressure transducers. In addition, the pressure transducer holder may move relative to the support member to one of a plurality of different vertically elevated positions. The pressure transducer mounting device may accommodate different pressure transducers, providing a universal mounting device that can adapt to different medical provider preferences and different pressure transducer sourcing options.

Abstract: An improved injection port for implantation within a patient having an x-ray discernable marker allowing for the determination of a pressure rating for the injection port when so implanted.

Abstract: A vacuum mixing device for mixing PMMA bone cement from a monomer liquid and a cement powder, the vacuum mixing device comprising at least one cartridge comprising an evacuable interior for mixing of the bone cement, a mixing device for mixing the content in the interior of the at least one cartridge, which is arranged movably in the interior, a receptacle for receiving a separate container containing the monomer liquid or comprising an integrated container containing the monomer liquid, an opening device, which is arranged in the region of the receptacle in a manner movable relative to the receptacle so that, by moving the opening device, a separate container arranged in the receptacle is openable by means of the opening device, or the opening device is arranged in the region of the integrated container in a manner movable relative to the integrated container so that, by moving the opening device, the integrated container is openable by means of the opening device, a pump, in which a movable plunger for gene

Abstract: The invention relates to a mixing device for mixing PMMA bone cement from a monomer liquid and a cement powder, the mixing device comprising at least one cartridge having an evacuable interior for mixing of the bone cement, a mixing device for mixing the content in the interior of the at least one cartridge, which is arranged movably in the interior, a receptacle for receiving a separate container containing the monomer liquid or comprising an integrated container containing the monomer liquid, an opening device, which is arranged in the region of the receptacle in a manner movable relative to the receptacle so that, by moving the opening device, a separate container arranged in the receptacle is openable by means of the opening device, or the opening device is arranged in the region of the integrated container in a manner movable relative to the integrated container so that, by moving the opening device, the integrated container is openable by means of the opening device, a pressure pump, in which a movable

Abstract: An infusion pump assembly includes an enclosure assembly. A reservoir assembly is positioned at least partially within the enclosure assembly and is configured to contain an infusible fluid. A pump assembly is positioned at least partially within the enclosure assembly and is configured to effectuate the dispensing of the infusible fluid contained within the reservoir assembly. Processing logic is positioned at least partially within the enclosure assembly and is configured to control the pump assembly. A removable cover assembly is configured to releasably engage the enclosure assembly. A combination of the removable cover assembly and at least a portion of the enclosure assembly defines a power supply cavity configured to prevent a removable power supply assembly from being reverse-polarity electrically coupled to the processing logic.

Abstract: A power-injectable access port suitable for injecting contrast media therethrough at a rate of at least 1 milliliter per second. The access port includes a housing, a septum, a reservoir, and an outlet stem in fluid communication with the reservoir. The power-injectable access port is structured for accommodating a pressure developed within the reservoir of at least 35 psi. The septum may include a radiopaque material forming a selected pattern when an x-ray is taken through the septum. The pattern may identify the access port as capable of accommodating injection of contrast media at a rate of at least 1 milliliter per second and/or as capable of accommodating a pressure developed within the reservoir of at least 35 psi. The pattern may identify the location of the septum following implantation of the power-injectable access port.

Abstract: A system for aspirating thrombus includes a catheter having a supply lumen having a distal end and an aspiration lumen configured to couple to a vacuum source and having an interior wall surface and an open distal end, an orifice at or near the distal end of the supply lumen, in fluid communication with the interior of the aspiration lumen, the orifice located proximally of the open distal end of the aspiration lumen, wherein the orifice is configured to create a spray pattern that impinges on the interior wall surface of the aspiration lumen when a distal end of the aspiration catheter is immersed within an aqueous environment, and a disposable tubing set having a first conduit configured to couple the supply lumen of the aspiration catheter to a fluid source, and a pump component associated with the first conduit and configured to detachably couple to a drive unit.

Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Abstract: The invention faces the technical problem of reducing the uncertainty over exact doses ejected from a medical device and at the same time providing a homogeneous, but controlled mixture of at least two fluids while a simple production should be maintained. A medical device comprising a first valve, a second valve, a first pre-valve ullage, a second pre-valve ullage, a post-valve ullage with a first end and a second end and a needle is presented. The first pre-valve ullage is connected to the post-valve ullage by the first valve and the second pre-valve ullage is connected to the post-valve ullage by the second valve. A first fluid is guidable from the first pre-valve ullage to the post-valve ullage and a second fluid is guidable from the second pre-valve ullage to the post-valve ullage.

Abstract: A manual mixer serves to facilitate mixing and agitating materials for use during surgery. For example, the manual mixer includes a body portion defining an interior area, a mixing assembly provided in the interior area of the body portion, a crank assembly for actuating the mixing assembly, and a valve assembly. The mixing assembly serves to mix and agitate the materials provided in the interior through rotation of a plunger portion and a spring attached thereto, and through upwards and downwards movement of the plunger portion in the interior area. Rotation of the crank assembly serves to rotate the plunger portion and the spring attached thereto, and effectuate upwards and downwards movement of the plunger portion. The valve assembly can be opened to facilitate dispensing of the materials from the interior area.

Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.

Abstract: A triple three-way valve device comprises: a valve body (1) having a distal end and a proximal end, wherein the proximal end of the valve body (1) is connected with a control knob (2) that is radially rotatable relative to the valve body (1); and a valve rod (3) having a distal end and a proximal end, wherein the valve rod (3) is provided within the valve body (1) and is fixedly connected with the control knob (2). The distal end of the valve body (1) is connected with a seat body (4), which is connected with a plurality of liquid passages and a high pressure pipe passage; a selection member (5) provided at the distal end of the valve body (1), wherein, depending on the position of the control knob (2), the selection member (5) selects the communication relationships between the plurality of liquid passages of the seat body (4), the high pressure pipe passage and the valve rod. With the triple three-way valve device, angiocardiography surgery is simplified, and surgery safety and efficiency are improved.