Abstract: A power-injectable access port suitable for injecting contrast media therethrough at a rate of at least 1 milliliter per second. The access port includes a housing, a septum, a reservoir, and an outlet stem in fluid communication with the reservoir. The power-injectable access port is structured for accommodating a pressure developed within the reservoir of at least 35 psi. The septum may include a radiopaque material forming a selected pattern when an x-ray is taken through the septum. The pattern may identify the access port as capable of accommodating injection of contrast media at a rate of at least 1 milliliter per second and/or as capable of accommodating a pressure developed within the reservoir of at least 35 psi. The pattern may identify the location of the septum following implantation of the power-injectable access port.

Abstract: A system for aspirating thrombus includes a catheter having a supply lumen having a distal end and an aspiration lumen configured to couple to a vacuum source and having an interior wall surface and an open distal end, an orifice at or near the distal end of the supply lumen, in fluid communication with the interior of the aspiration lumen, the orifice located proximally of the open distal end of the aspiration lumen, wherein the orifice is configured to create a spray pattern that impinges on the interior wall surface of the aspiration lumen when a distal end of the aspiration catheter is immersed within an aqueous environment, and a disposable tubing set having a first conduit configured to couple the supply lumen of the aspiration catheter to a fluid source, and a pump component associated with the first conduit and configured to detachably couple to a drive unit.

Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Abstract: The invention faces the technical problem of reducing the uncertainty over exact doses ejected from a medical device and at the same time providing a homogeneous, but controlled mixture of at least two fluids while a simple production should be maintained. A medical device comprising a first valve, a second valve, a first pre-valve ullage, a second pre-valve ullage, a post-valve ullage with a first end and a second end and a needle is presented. The first pre-valve ullage is connected to the post-valve ullage by the first valve and the second pre-valve ullage is connected to the post-valve ullage by the second valve. A first fluid is guidable from the first pre-valve ullage to the post-valve ullage and a second fluid is guidable from the second pre-valve ullage to the post-valve ullage.

Abstract: A manual mixer serves to facilitate mixing and agitating materials for use during surgery. For example, the manual mixer includes a body portion defining an interior area, a mixing assembly provided in the interior area of the body portion, a crank assembly for actuating the mixing assembly, and a valve assembly. The mixing assembly serves to mix and agitate the materials provided in the interior through rotation of a plunger portion and a spring attached thereto, and through upwards and downwards movement of the plunger portion in the interior area. Rotation of the crank assembly serves to rotate the plunger portion and the spring attached thereto, and effectuate upwards and downwards movement of the plunger portion. The valve assembly can be opened to facilitate dispensing of the materials from the interior area.

Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.

Abstract: A triple three-way valve device comprises: a valve body (1) having a distal end and a proximal end, wherein the proximal end of the valve body (1) is connected with a control knob (2) that is radially rotatable relative to the valve body (1); and a valve rod (3) having a distal end and a proximal end, wherein the valve rod (3) is provided within the valve body (1) and is fixedly connected with the control knob (2). The distal end of the valve body (1) is connected with a seat body (4), which is connected with a plurality of liquid passages and a high pressure pipe passage; a selection member (5) provided at the distal end of the valve body (1), wherein, depending on the position of the control knob (2), the selection member (5) selects the communication relationships between the plurality of liquid passages of the seat body (4), the high pressure pipe passage and the valve rod. With the triple three-way valve device, angiocardiography surgery is simplified, and surgery safety and efficiency are improved.

Abstract: A fluid injection system for use with a syringe is disclosed. The fluid injection system includes a housing, a drive member at least partially disposed within the housing, at least one radially retractable pin disposed within the drive member, and a sensor positioned to sense rearward movement of a sensing pin in the drive member. The at least one pin is adapted to form a radially retractable abutting connection with a plunger of the syringe in response to axial movement of the drive member. Further, at least a portion of the pin is radially extendable and retractable through at least one radial passage in the drive member, and is retracted within the radial passage during forward movement of the drive member, and extends radially outward through the radial passage during rearward movement of the drive member.

Abstract: Provided is an auto-injector for a syringe suitable for the injected delivery of drug to a patient. The auto-injector comprises a cassette unit arranged for receipt of a syringe. The cassette unit and/or syringe is movable from a rest position, in which the syringe needle tip is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture thereof. The auto-injector comprises a drive unit arranged for docking receipt of the cassette unit at a docking position and a drive arrangement. The drive unit is arranged for initial receipt of the cassette unit at an intermediate pre-docking position and for subsequent transport of the cassette unit to the docking position. In embodiments, the drive unit is arranged such that transport of the cassette unit to the docking position is permitted only following verification of an identifier at the intermediate pre-docking position.

Abstract: A vial adapter includes a base having first and second opposing sides, a spike depending from the first side of the base, the spike having a spike passageway, and a connector disposed on the second side of the base, the connector having a connector passageway that is in fluid communication with the spike passageway. The vial adapter may be combined with a vial.

Abstract: A status messaging protocol (140) for a power injector (10) is disclosed. A setup screen (230) may be displayed on a graphical user interface (11) associated with the power injector (10). A status message (268) is displayed in a status message zone (266) on the setup screen (230). As the status of the power injector (10) changes, the status message (268) in the status message zone (266) on the setup screen (230) is updated.

Abstract: A programmable pickup director switching system for a musical instrument having a plurality of pickup coils and a pickup director control board communicatively interconnected to the plurality of pickup coils. The system also includes a push/pull potentiometer structured and arranged to activate different combinations of one or more of the plurality of pickup coils, a main multi-position switch having m positions, and a bank select switch having n positions. Additionally, the system includes a switching matrix configured to switch one or more of the plurality of pickup coils into a signal path based on a position of at least one of the main multi-position switch, the bank select switch and the push/pull potentiometer.

Abstract: The invention is related to a dispense interface for a drug delivery device for delivering at least two drug agents, wherein the dispense interface is configured to be coupled to a cartridge holder of the drug delivery device, wherein the cartridge holder is configured to hold at least two cartridges, wherein the dispense interface comprises at least two inlet channels, each comprising a fluid inlet opening, wherein each fluid inlet opening is configured to receive fluid from a respective cartridge of the at least two cartridges when the dispense interface is axially coupled to the cartridge holder, an outlet channel comprising a fluid outlet opening, a valve structure configured to be selectively moved into any one of a plurality of positions, wherein in at least one position the valve structure selectively permits or prevents fluid flow from any of the at least two inlet channels to the outlet channel.

Abstract: The invention relates to a sensor arrangement for the detection of specimen containers within a detection zone, with an optical sensor having an image sensor at a first end of the detection zone, and with a textured background at a second end of the detection zone, A specimen container arranged within the detection zone is detected by the image sensor against the textured background. The specimen container is differentiated from the textured background by an evaluation unit, based on the image signals generated by the image sensor, and object detection signals that identify the specimen container are generated.

Abstract: A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.

Abstract: A disposable injector with a cylinder/piston unit that can be filled at least temporarily with active substance, with a housing in which a pretensioned and releasable mechanical spring energy reservoir is arranged, and with at least one piston-actuating ram positioned between the spring energy reservoir and the piston of the cylinder/piston unit. The piston-actuating ram has two draw hooks that engage around the housing in some areas. In addition, the piston-actuating ram is separable from the housing by the relaxing spring energy reservoir. With the present invention, a disposable injector is developed which, with a small overall size, comprises only a small number of components and, while being easy to handle, ensures safe storage and operation.

Abstract: A medical fluid injection system may include a powered injector and a fluid reservoir that contains a simulated contrast medium. The simulated contrast medium may exhibit a fluid flow property substantially equal to that of an active contrast medium but be devoid of any active contrast agent that provides contrast during diagnostic imaging. During operation, a syringe in the powered injector may be filled with the simulated contrast medium and then evacuated to discharge the simulated contrast medium from the syringe. The simulated contrast medium may be used to test and evaluate the performance of the powered injector prior to use in a medical procedure without exposing personnel to an active contrast agent or creating medical waste that contains the active contrast agent.

Abstract: Probes for monitoring electrostatic phenomena in challenging environments, such as fluidized bed reactors. These probes include a coated or uncoated static probe for measuring electric field and or particle charge state, an oscillatory electric field probe for measuring electric field, a chopped electric field probe for measuring electric field, and a radio-frequency antenna probe for detecting electrostatic discharges.

Abstract: An injector system, method and computer program product for detecting a vacuum within a syringe are provided. Various embodiments include an actuator device configured to be engaged with a piston member of a syringe for extending and retracting the piston member within the syringe. A controller device is also provided for detecting an output generated by the actuator device when retracting the piston member. The detected output may be associated with a pressure within the reservoir. The controller device determines, via the detected output, when the pressure comprises a selected negative pressure and provides an indicia of the negative pressure to a user and/or a signal to the actuator device.

Abstract: A system and method to automatically initiate an injection procedure of a medicament into a patient. In the system, a delivery assembly includes an injector for infusing the medicament into the patient. Further, the system includes a monitor for detecting a parameter characteristic of the procedure, for instance, a pressure indicative of a partial vacuum between the injector and the injection site, a pressure exerted by the patient against the delivery assembly, a conductance, a capacitance, or an optical blood reading. Also, the system includes a timer for determining compliance of the parameter within a predetermined range during a first time interval. In response to the timer, an actuator initiates the injection procedure at the expiration of the first time interval. Further, the actuator may stop the injection procedure if the parameter is outside the predetermined range during a second time interval.

Abstract: Disclosed herein are various embodiments of devices, systems and methods for the delivery of carbon dioxide (CO2) as a contrast agent for angiography. The CO2 delivery device can include a syringe and a shuttle valve assembly in fluid communication with the syringe, such that the shuttle valve can be disposed in a first position to pressurize the syringe with CO2, and a second position to deliver a bolus of CO2 to a subject.

Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.

Abstract: The present invention relates to the medical field, in particular relates to the practice of percutaneous vertebroplasty where a pair of syringes in the distal extreme of a lengthened hydraulic device, are united by a camera of intermediate connection of larger diameter (pressure exerting body) or modified inverted syringe tube with a bolster, a hydraulic connecting tube of flexible material that transmits the pressure of the smaller diameter manual or impulsion syringe in the proximal extreme of the device toward the intermediate cylindrical larger diameter camera (pressure exerting body), this camera is in an inverted position with regard to the first syringe (fluid control), this intermediate camera has a moving piston longitudinal to the axis of the cylinder that is controlled with the first syringe (manual) and in cooperation with the atmospheric pressure.

Abstract: A novel one-piece fluid reservoir assembly for use in conjunction with an insulin infusion pump. The single piece fluid reservoir assembly includes a barrel body, a male luer fitting integral with the barrel body, a sealing surface integral with the barrel body, the sealing surface for sealing against the pump housing when the fluid reservoir assembly is inserted into the pump housing. Further, the barrel includes, as part of the one-piece fluid reservoir assembly, threads for engagement with threads on an opening in the fluid pump so that the fluid assembly can be inserted into the fluid pump, engage the threads and rotation therewith will locate the fluid reservoir assembly within the pump. Thereafter, a piston in the pump may be incrementally advanced to act upon a plunger in the barrel assembly to force a fluid within the barrel assembly through the male luer fitting and through a conduit engaged therewith to a remote infusion set.

Abstract: A method of programming a medical infusion pump with a protocol is disclosed. The method includes providing a protocol including one or more patient specific pump parameters. The method further includes providing a user interface configured to allow user adjustment of at least one of the one or more patient specific pump parameters. The method also includes uploading the protocol into the medical infusion pump.

Abstract: An improved spindle and bearing combination for a drug delivery device is provided that has a first connection between the spindle (1) and bearing (4) comprising a web (5) and a second connection that replaces the first connection when the web (5) is severed that allows the spindle (1) to rotate relative to the bearing (4).

Abstract: In a special mode, a first frame image including a blue signal B1, a green signal G1, and a red signal R1 is captured in a first frame period. In a second frame period, a second frame image including a blue signal B2, a green signal G2, and a red signal R2 is captured. An oxygen saturation level calculator calculates an oxygen saturation level of each pixel based on signal ratios B1/G2 and R2/G2, and sequentially outputs obtained special images on a monitor. Whenever the special image is produced, a signal ratio R2/R1 is calculated. When the signal ratio R2/R1 exceeds a threshold value, a warning sign “!!” is displayed. When the signal ratio R2/R1 is larger than a predetermined range S, a warning sign “HIGH StO2” is displayed. When the signal ratio R2/R1 is smaller than the range S, a warning sign “LOW StO2” is displayed.

Abstract: Chemical liquid injector 100 includes two piston driving mechanisms 130 each moving a piston of a syringe forward, main injection condition determining section 171 determining injection conditions for a chemical liquid in main injection, test injection condition determining section 172 determining injection conditions for the chemical liquid in test injection performed prior to the main injection to inject a smaller injection amount of the chemical liquid than that in the main injection, and control section 161 creating an injection protocol in accordance with the injection conditions determined by test injection condition determining section 171 and main injection condition determining section 172 such that the chemical liquid is injected in a series of operations in which the test injection is performed, then a preset injection suspension time is present, and subsequently the main injection is performed, and further controlling operation of piston driving mechanisms 130 in accordance with the injection prot

Abstract: A powered medical fluid injector may have a disposable medical fluid injection manifold that controls fluid routing between the injector and a patient line and also controls fluid flow to a pressure sensor contained within the manifold. In one example, the medical fluid injection manifold includes a manifold housing having at least two inlets for different pressurized medical fluids and at least two corresponding outlets. The medical fluid injection manifold may also have a pressure sensor configured to measure a hemodynamic pressure of a patient. The pressure sensor may be positioned within the manifold housing and in selective fluid communication with the one of the outlet ports of the manifold housing.

Abstract: A system for the effective, reliable and foolproof delivery of controlled amounts of a medical fluid to a patient is provided. The system includes an integrated compressed gas unit having an inlet port to which at least one compressed gas cylinder is selectively connected and an outlet port in communication with the inlet port. The integrated compressed gas unit also includes a regulator valve assembly positioned between the outlet port and the inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. The system also includes a flow control system delivering the fluid in precisely controlled amounts.

Abstract: A telepresence robot uses a series of connectible modules and preferably includes a head module adapted to receive and cooperate with a third party telecommunication device that includes a display screen. The module design provides cost advantages with respect to shipping and storage while also allowing flexibility in robot configuration and specialized applications.

Abstract: Systems and methods are presented for the visual indication of whether a power injector has discharged fluid from a power injector syringe in a previous medical procedure. In this regard, the systems and methods generally provide for a power injector and a syringe for use with the power injector. The syringe includes a visual indicator that moves between a first state and a second state at approximately the same time that the power injector discharges fluid from the syringe such that an operator may view the change in state.

Abstract: A medical fluid injection system may include a powered injector and a fluid reservoir that contains a simulated contrast medium. The simulated contrast medium may exhibit a fluid flow property substantially equal to that of an active contrast medium but be devoid of any active contrast agent that provides contrast during diagnostic imaging. During operation, a syringe in the powered injector may be filled with the simulated contrast medium and then evacuated to discharge the simulated contrast medium from the syringe. The simulated contrast medium may be used to test and evaluate the performance of the powered injector prior to use in a medical procedure without exposing personnel to an active contrast agent or creating medical waste that contains the active contrast agent.

Abstract: A catheter has a shaft that defines a delivery lumen, for example, to deliver an elongate medical device therethrough; a proximal section of the catheter includes a seal zone portion, a handle portion and a proximal port portion. A relatively thin wall section of the proximal port portion extends between the seal zone portion and a proximal edge that defines part of a perimeter of a proximal opening of the delivery lumen. The handle portion projects laterally from the seal zone portion, generally opposite the relatively thin wall section. An inflation subassembly of the catheter includes a compliant sleeve member and an inflation lumen extending from the sleeve member, proximally along the shaft, and into a connector port formed in the handle portion. The inflation lumen may be formed by fusing a section of a tube to the shaft and molding the handle portion around another section of the tube.

Abstract: An infusion system includes a double action infusion pump. The pump includes a cylinder and a reciprocating piston received within the cylinder, the reciprocating piston separating a first pump chamber from a second pump chamber of the cylinder. A reciprocating motor is coupled with the reciprocating piston, and the first and second pump chambers alternate between filling and evacuating conditions with reciprocation of the reciprocating piston through operation of the reciprocating motor, and the speed of reciprocation is varied to provide a continuous output of fluid between the first and second pump chambers. A fluid source and a catheter are optionally coupled with the double action infusion pump. The catheter includes one or more infusion ports near a catheter distal portion, and the one or more infusion ports receive and expel the continuous output of fluid from the double action infusion pump.

Abstract: A pressure isolation mechanism for use in a medical procedure includes a lumen, an isolation port in fluid connection with lumen, and a valve having a first state and a second state. The first state occurs when the lumen and the isolation port are connected. The second state occurs when the lumen and the isolation port are disconnected. The lumen remains open for flow of fluid therethrough in the first state and in the second state. The valve is normally in the first state and is switchable to the second state when fluid pressure in the lumen reaches a predetermined pressure level. A pressure transducer can be in fluid connection with the isolation port of the pressure isolation mechanism A fluid delivery system includes a manually operated syringe and a pressure isolation mechanism as described above.

Abstract: An apparatus (130) and a method for adjusting, in perfusion imaging system, a periodic contrast agent injection rate signal (IS) for an injector (135) as function of an image sampling rate determined by the rotational speed of an X-ray source (107)-detector (109) assembly of an X-ray imager (100). Frequency, periodicity and pulse width of the contrast agent injection rate signal (IS) is adjusted to mitigate temporal signal aliasing in a sample of a time attenuation contrast (TAC) signal.

Abstract: A contrast media injection system includes detects the absolute position of the syringe ram using a non-contact sensor. A series of magnets and Hall-Effect sensors may be used or an opto-reflective system. Illuminated knobs that are connected to the drive mechanism for the syringe ram rotate with the drive and provide visual feedback on operation through the illumination. Analog Hall-Effect sensors are used to determine the presence or absence of magnets that identify the type of faceplate being used. The faceplates include control electronics, connected to the powerhead through connectors, which may be interchangeably used by the two faceplates. The faceplate electronics include detectors for automatically detecting the capacity of pre-filled syringes.

Abstract: Multiple embodiments of contrast media injector systems (800, 800?, 800c) are disclosed. A number of different devices are disclosed for providing user input to such a contrast media injector system (800, 800?, 800c), including at least one tablet computer (700), a user-mountable user input device (760), a smartphone (762), and various combinations thereof.

Abstract: A liquid injector registers the data of a variable pattern in which an injection rate of a contrast medium varies with time. The injection rate of the contrast medium varies with time according to the variable pattern for maintaining a state in which the image contrast achieved by the contrast medium approximates an optimum level.

Abstract: A marker deployment tool may comprise a marker cannula having a lateral deployment aperture, a push rod slidably disposed within the marker cannula and a scalloped tip coupled to the distal end of the marker cannula. The scalloped tip may have a push rod recess configured to receive a portion of the distal end of the push rod such that the push rod does not appreciably extend out of the lateral deployment aperture when the push rod is actuated distally. The marker deployment tool may further comprise a magnet at or near the distal end. This magnet may be used in combination with a magnet or plurality of magnets disposed about an access chamber in a tissue sample holder to assist the user in aligning the marker deployment tool. The access chamber in the tissue sample holder may also include a valve, two valves, or a removable plug.

Abstract: A method for using CO2 as a contrast material in medical imaging procedures is disclosed. The method includes providing a source of pressurized CO2. The step of providing includes connecting the source of pressurized CO2 to a compressed gas unit for controlling delivery of the CO2. The method also includes regulating pressure of the CO2 delivered by the compressed gas unit, transmitting the pressurized CO2 from the compressed gas unit to a control valve assembly for delivery to a patient in controlled dosages, and sequentially processing the CO2 with the control valve assembly and delivering the CO2 to the patient as a contrast media.

Abstract: A medical examination apparatus including a control unit, an image-generating modality and a controllable injection apparatus for a contrast agent is provided. The control unit is connected to an alarm signal emitter and the control unit switches the modality and the injection apparatus to a safe mode as a function of an alarm signal.

Abstract: A medical fluid injection system may include a powered injector and a fluid reservoir that contains a simulated contrast medium. The simulated contrast medium may exhibit a fluid flow property substantially equal to that of an active contrast medium but be devoid of any active contrast agent that provides contrast during diagnostic imaging. During operation, a syringe in the powered injector may be filled with the simulated contrast medium and then evacuated to discharge the simulated contrast medium from the syringe. The simulated contrast medium may be used to test and evaluate the performance of the powered injector prior to use in a medical procedure without exposing personnel to an active contrast agent or creating medical waste that contains the active contrast agent.

Abstract: A medical device that may include an elongate member having a proximal end and a distal end, and a lumen disposed through the elongate member is disclosed. The medical device may also include an opening disposed at the distal end of the elongate member in communication with the lumen, and a pushing element disposed with the lumen. The medical device may also include at least one fiducial disposed within the lumen and distal to the pushing element, and a separating mechanism disposed at the distal end of the elongate member. The separating mechanism may be configured to apply a separating force to deploy the at least one fiducial.

Abstract: Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/or UV spectroscopy.

Abstract: The present invention relates to novel formulations comprising a plurality of nano-sized solid particles and a gel-forming system, useful, e.g. for imaging of the body of a mammal. Also described are kits comprising such formulations and imaging methods utilizing such formulations or kits.

Abstract: A control unit for an equipment arrangement is provided. The control unit includes an imaging modality, a measurement device for measuring a control variable and a controllable injection device for a regulatory substance influencing the control variable, wherein the injection rate of the injection device may be varied during a data acquisition such that a proposed value for the control variable is reached.

Abstract: An injector automatic limiting of the operating pressure of the injector as determined by the selection of a flow rate; a syringe cradle having a warming capability; a purge/retract trigger for control of the injection procedure having intuitive direction (i.e., forward for injecting, reverse for filing), non-contact control transmission through the housing of an injector for an improved seal integrity, a speed lock, and/or the ability to change the concentration and/or flow rate of media or other fluid during an injection procedure; a switch to determine when the drive ram is in a “home” position; a “soft” on/off power switch separate from the injector; and a structure to prevent rotation of the drive ram about its axis of symmetry. Additionally, the injector system includes software for the control of various components.

Abstract: A liquid injector (400) injects a medical liquid into a patient whose fluoroscopic image data is to be picked up and generates injection history data corresponding to the injection, and a control box (500) registers the injection history data in a RIS (100) in association with imaging order data. Accordingly, the RIS (100) also stores the injection history data associated with the imaging order data, and therefore the injection history data can also be confirmed based on the imaging order data.