Using Flexible Catheter Patents (Class 600/433)
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Patent number: 8855746Abstract: An endoscopic medical tool is endoscopically inserted into a body cavity in order to eject a member into the body cavity, and includes: a flexible sheath having an inner cavity; an elastically deformable stopper which is provided projecting out toward the inner cavity in a distal end portion of the sheath, and prevents the member which has been loaded inside the sheath from falling out of the sheath; and a pusher which is inserted into the sheath in a freely advancing and retracting manner, and which pushes out and ejects the member from the sheath. In the endoscopic medical tool, the stopper is formed in only a partial region of the inner cavity so that the stopper does not continuously formed over the entire circumference of the inner cavity.Type: GrantFiled: August 3, 2009Date of Patent: October 7, 2014Assignee: Olympus Medical Systems Corp.Inventor: Masaru Yuasa
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Publication number: 20140276042Abstract: An integrated catheter and powered injector system includes a pump housed in a self-contained unit, a contrast media supply removably connected to the pump by a fluid supply line, an extension line removably connecting an arterial catheter to the pump, and a control device sending user control signals to the pump. The pump comprises a motorized pump drive sub-system operating the pump, and a battery electrically connected to and powering the pump drive sub-system. In response to signals received from the control device, the pump drive sub-system drives the pump to draw contrast media fluid from the supply into the pump through the fluid supply line and inject the contrast media fluid from the output of the pump through the extension line and into the arterial catheter at a controlled flow rate and/or pressure.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: SYNTHEON, LLCInventors: KEVIN W. SMITH, THOMAS O. BALES, JR., KOREY KLINE, MATTHEW A. PALMER, SEAN McBRAYER, DEREK DEE DEVILLE, ERIC PETERSEN
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Patent number: 8821476Abstract: Devices and methods are described herein for engraftment of stem cells into a pancreas using an endovascular approach. Targeted intra-arterial injection of stem cells selectively in a splenic artery can achieve engraftment of insulin producing cells in the tail of the pancreas with high efficiency and without systemic circulation of these cells to other organs. In one embodiment, a catheter device includes expandable occlusion elements in the form of inflatable balloons that can be used to isolate a proximal and distal end of a pancreatic portion of the splenic artery. In another embodiment, the occlusion elements include a filter element instead of a balloon. In some embodiments, targeted delivery of stem cells to the pancreatic tail can be achieved for treatment of, for example, diabetes. In some embodiments, an arterial section of the splenic artery can be isolated for selective perfusion of therapeutic cells/drugs to the tail of the pancreas.Type: GrantFiled: December 2, 2010Date of Patent: September 2, 2014Assignee: RenovoRx, Inc.Inventors: Ramtin Agah, Kamran Najmabadi
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Publication number: 20140236005Abstract: A method of imaging a blood vessel includes delivering a bubble-based contrast agent within the vessel and positioning at least one ultrasound device in the vicinity of the bubble-based contrast agent within the vessel. A first burst of low-frequency ultrasound energy can be delivered to excite the bubble-based contrast agent into oscillation within the vessel, and a second burst of high-frequency ultrasound energy can be delivered at the excited bubble-based contrast agent. A return signal from the burst of high-frequency ultrasound energy can be received and processed to obtain one or more images.Type: ApplicationFiled: August 24, 2012Publication date: August 21, 2014Applicant: University of Pittsburgh-Of the Commonwealth Systems of Higher EducationInventors: Xucai Chen, Francois T.H. Yu, Flordeliza S. Villanueva
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Patent number: 8734366Abstract: The invention provides a method for replacing a first introducer, whose distal end is inside a vessel and whose proximal end is outside the skin of a patient, with a second introducer. The method comprises the steps of inserting a guide rod into the first introducer, removing the first introducer, passing the second introducer over the guide rod, and removing the guide rod. The guide rod to be used according to the method has preferably a flexible distal portion with a blunt distal end and a stiff proximal portion with a tapered proximal end.Type: GrantFiled: July 10, 2006Date of Patent: May 27, 2014Assignee: Radi Medical Systems ABInventors: Per Egnelöv, Fredrik Preinitz, Lars Tenerz
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Publication number: 20140121514Abstract: Novel methods and imaging agents for functional imaging of lymph structures are disclosed herein. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques to track or monitor packets of organic dye flowing in one or more lymphatic structures. The packets of organic dye may be tracked to provide quantitative information regarding lymph propulsion and function. In particular, lymph flow velocity and pulse frequency may be determined using the disclosed methods.Type: ApplicationFiled: November 5, 2013Publication date: May 1, 2014Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Kristen ADAMS, Ruchi SHARMA, John C. RASMUSSEN, Eva M. SEVICK-MURACA
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Patent number: 8706198Abstract: A catheter device comprising a chamber containing an opacity enhancing substance is disclosed. The opacity enhancing substance is in a dried or semi-dried form within the chamber of the device. Release of a liquid into the chamber suspends the substance and forms an opacity enhancing solution that is released into the lumen of the device in order to enhance the opacity of the device for imaging.Type: GrantFiled: June 30, 2011Date of Patent: April 22, 2014Assignee: Quali-Med GmbHInventor: Eric K. Mangiardi
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Patent number: 8694077Abstract: An apparatus for targeting a desired target site on a body tissue that separates a first body cavity from a second body cavity of a patient includes a catheter having a longitudinally extending catheter lumen and adapted to provide access to the first body cavity. A framing member has a collapsed condition in which the framing member is adapted for insertion into the first body cavity through the catheter lumen and an expanded condition in which the framing member is adapted for placement within the first body cavity. The framing member has a framing member body. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway extends through the catheter lumen. The target pathway is substantially spaced apart from the framing member body. A method of using the apparatus is also described.Type: GrantFiled: August 10, 2011Date of Patent: April 8, 2014Assignee: The Cleveland Clinic FoundationInventor: Samir Kapadia
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Patent number: 8670818Abstract: A marker delivery device is configured for deploying a tissue marker. The marker delivery device includes a handle having a chamber, and a cannula. According to one aspect, the cannula has a flexible portion formed by a slot arrangement having of a plurality of spaced-apart substantially parallel peripheral slots extending through the side wall of the cannula to the lumen. A marker introducer rod is movably disposed in the lumen of the cannula for deploying the mark, and has a flexible region that corresponds to the flexible portion of the cannula. According to another aspect, a retraction mechanism is mounted to the handle and is configured to facilitate a complete retraction of both the cannula and the marker introducer rod into the chamber of the housing of the handle upon an actuation of the retraction mechanism.Type: GrantFiled: December 30, 2008Date of Patent: March 11, 2014Assignee: C. R. Bard, Inc.Inventors: Himanshu Ranpura, Chad C. Van Liere
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Publication number: 20140051997Abstract: Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.Type: ApplicationFiled: February 8, 2013Publication date: February 20, 2014Applicant: ADVANCED CATHETER THERAPIESInventor: ADVANCED CATHETER THERAPIES
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Blood flow bypass catheters and methods for the delivery of medium to the vasculature and body ducts
Patent number: 8655798Abstract: A catheterization device that may be designed by use of an adaptive genetic algorithm computational fluid dynamics approach, as well as other Global Optimization methods that may include simulated annealing, multistart and interval methods, continuous branch and bound methods, evolutionary algorithms, and tabu search and scatter search methods, as well as other available Global Optimization methods that is able to maximize/optimize the dwell time of an infused agent in the vicinity of a vascular lesion. The device may have an internal by-pass channel that allows the blood upstream of the lesion to continue its pulsatile flow through the vessel in the part of it occluded by the lesion, while simultaneously allowing the disbursement and maximal dwell time of an antithrombolytic or other diagnostic or therapeutic agent needed to treat the lesion.Type: GrantFiled: July 26, 2012Date of Patent: February 18, 2014Assignee: University of Virginia Patent FoundationInventors: Joseph A. C. Humphrey, George T. Gillies -
Patent number: 8649847Abstract: A biopsy needle has a central axis and includes one or more sensing regions, each sensing region formed by a plurality of sensing optical fibers located over a particular extent of said central axis and inside the outer shell of the needle. The sensing optical fibers are coupled to a wavelength interrogator. A steerable catheter has a central axis and outer shell, the outer shell coupled to a plurality of optical fibers in sensing regions and actuation regions, the sensing regions formed over particular extents of the central axis by bonding gratings to the inner surface of the outer shell, and the actuation regions formed by coupling optical energy into shape memory alloys bonded to the outer shell.Type: GrantFiled: September 18, 2009Date of Patent: February 11, 2014Assignee: Intelligent Fiber Optic Systems, Inc.Inventors: Yong-Lae Park, Richard James Black, Behzad Moslehi, Mark R. Cutkosky, Santhi Elayaperumal, Bruce Daniel, Alan Yeung, Vahid Sotoudeh
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Patent number: 8615287Abstract: Methods and systems are disclosed for determining information about a position of an object within a distribution of materials having different complex conductivities. The method includes: (i) causing current to flow in the distribution; (ii) measuring an electrical signal at each of multiple locations in the distribution of materials in response to the current flow; (iii) providing spatial information about the distribution of materials with respect to a first reference frame, the spatial information indicative of regions of different complex conductivity in the distribution of materials; and (iv) determining the position of the object with respect to the spatial information about the distribution of materials based on measured electrical signals and the spatial information. In certain embodiments, the object is a catheter inserted into a patients heart cavity for cardiac mapping.Type: GrantFiled: August 30, 2010Date of Patent: December 24, 2013Assignee: Rhythmia Medical, Inc.Inventors: Doron Harlev, Adam Pidlisecky
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Patent number: 8611989Abstract: A method of generating an image of a segment of a lumen structure comprises acquiring volumetric image data that comprises image data representative of a longitudinal segment of a lumen structure, extracting the segment of lumen structure from the volumetric image, calculating a thickness of planar MPR slab that at least encompasses the longitudinal segment of lumen structure, and rendering a planar MPR slab image based on the thickness and the volumetric image data.Type: GrantFiled: November 30, 2010Date of Patent: December 17, 2013Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems CorporationInventor: Colin Roberts
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Patent number: 8610022Abstract: Methods of using the device for conducting business transactions are also included. An impedance spectroscopy system for monitoring ischemic mucosal damage in hollow viscous organs comprises a sensor catheter and an impedance spectrometer for electrically driving the catheter to obtain a complex tissue impedance spectrum. Once the catheter is in place in one of a patient's hollow viscous organs, the impedance spectrometer obtains the complex impedance spectrum by causing two electrodes in the tip of the catheter to inject a current into the mucosal tissue at different frequencies, while two other electrodes measure the resulting voltages. A pattern recognition system is then used to analyze the complex impedance spectrum and to quantify the severity of the mucosal injury. Alternatively, the complex impedance spectrum can be appropriately plotted against the spectrum of normal tissue, allowing for a visual comparison by trained personnel.Type: GrantFiled: December 27, 2011Date of Patent: December 17, 2013Inventor: Emilio Sacristan Rock
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Patent number: 8600479Abstract: A catheter system adapted for navigating, guiding and implanting a catheter or a plurality of catheters in a spatially-defined implantation within the tissue of a patient is provided. The system can include a tissue navigation system and a probe to inform the navigation system to guide emplacement of the catheters within a target tissue. The probe can provide images, such as fiberoptic visual images, or ultrasound images, or can provide radiolocation data, to guide the catheter emplacement. The catheters supply a pressurized liquid including a bioactive agent, such as can be used in the treatment of cancer, for example 123I- or 125I-IUDR. The system and methods provided can be used in the treatment of locally advanced tumors, such as cancers of the brain, head or neck, esophagus, prostate, ovary, liver, pancreas, bladder or rectum.Type: GrantFiled: March 20, 2008Date of Patent: December 3, 2013Assignee: Peak Biosciences, Inc.Inventors: William D. Dalke, Kevin Lillehei, Thomas A. Jellison, Michael J. Gerber, James E. Matsuura, Stephen L Warren
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Publication number: 20130317359Abstract: This disclosure provides systems and methods for measuring fluid flow in a vasculature system of a patient. Some systems may include an injection system configured to inject a bolus of fluid into a vessel of a patient. Some systems may include a measurement engine configured to monitor the bolus of fluid in the vessel using measurement data generated by an intravascular measuring device. The measurement engine may determine a travel distance of the bolus of fluid and an elapsed time during which the bolus of fluid traversed the travel distance based on the measurement data. A fluid flow rate (e.g., velocity, volumetric flow) of the vessel may be calculated using the travel distance and the elapsed time.Type: ApplicationFiled: May 24, 2013Publication date: November 28, 2013Inventors: Robert F. Wilson, Edward R. Miller, Sidney Donald Nystrom, Kendall R. Waters
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Publication number: 20130281850Abstract: An introducer having a dilator positioned in a sheath is inserted into a first artery and, thereafter, only the dilator tube is drawn out of the first artery and the sheath while the sheath remains in the first artery. A diagnostic instrument having an outer diameter smaller than a maximum outer diameter permitting insertion into the sheath tube is inserted into the second artery, and a stenosis of the second artery is diagnosed. While keeping the sheath indwelling in the first artery, a therapeutic instrument or a catheter permitting the therapeutic instrument to be inserted therein, which therapeutic instrument or catheter has a maximum outer diameter permitting insertion into the sheath tube, is inserted into the second artery, and the second artery is treated.Type: ApplicationFiled: April 19, 2013Publication date: October 24, 2013Applicant: TERUMO KABUSHIKI KAISHAInventors: Naofumi OKAJIMA, Ryo Okamura
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Patent number: 8560052Abstract: Echogenic medical devices, methods of fabrication and methods of use are disclosed. The device can be adapted to be inserted into a patient. The echogenic construction can be incorporated into the device at the time of fabrication providing acoustic impedance different from that of the surrounding biological tissue or fluid. The medical device is designed for use with an ultrasound imaging system to provide real-time location of the insertion and guidance at the time the device is implanted in a patient, such as in brachytherapy. Following placement of the device the position can be evaluated over time to insure the device remains in proper alignment and functional. Furthermore, the device is designed to incorporate a spacer element at one or both ends to provide separation between radioactive elements.Type: GrantFiled: April 20, 2004Date of Patent: October 15, 2013Assignee: Core Oncology, Inc.Inventor: Stanley L. Mills
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Patent number: 8549732Abstract: A surgical navigation system for navigating a region of a patient includes a non-invasive dynamic reference frame and/or fiducial marker, sensor tipped instruments, and isolator circuits. The dynamic reference frame may be repeatably placed on the patient in a precise location for guiding the instruments. The instruments may be precisely guided by positioning sensors near moveable portions of the instruments. Electrical sources may be electrically isolated from the patient.Type: GrantFiled: July 1, 2011Date of Patent: October 8, 2013Assignee: Medtronic Navigation, Inc.Inventors: Bruce M. Burg, John H. Dukesherer, Bradley A. Jascob, Paul Kessman
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Patent number: 8547425Abstract: The diagnosability of diseased parts is improved by precisely correcting fluorescence images without being affected by specular reflection and without being affected by thick blood vessels.Type: GrantFiled: January 30, 2008Date of Patent: October 1, 2013Assignee: Olympus CorporationInventor: Yasushige Ishihara
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Patent number: 8532749Abstract: A combination catheter enables performing an angiogram and an angioplasty (and repetitions of one or both) with the same catheter instrument, without removal from and re-insertion into an artery until the procedure is completed.Type: GrantFiled: January 14, 2011Date of Patent: September 10, 2013Inventor: Chris Patton
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Patent number: 8532738Abstract: A method, including constructing a simulated surface of a body cavity, and pressing a distal end of a probe against a wall of the body cavity. While pressing the distal end against the wall, position measurements are accepted from the probe indicating a position of the probe within the body cavity, and force measurements are accepted from the probe indicating a force between the distal end and the wall. A distortion in the simulated surface is created at the position indicated by the position measurements, so as to form a distorted surface, upon detecting that the force measurements exceed a predefined amount. The distorted surface is then displayed.Type: GrantFiled: November 4, 2010Date of Patent: September 10, 2013Assignee: Biosense Webster (Israel), Ltd.Inventor: Eliahu Zino
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Publication number: 20130225991Abstract: A power-injectable access port includes a housing defining an internal cavity and including a plurality of suture apertures, a needle-penetrable septum captured by the housing enabling needle access to the internal cavity, a stem having a lumen in fluid communication with the internal cavity, the stem configured for coupling to a catheter, and a radiopaque identification feature observable via imaging technology subsequent to subcutaneous implantation of the port, the feature indicating that the port is suitable for power injection.Type: ApplicationFiled: March 29, 2013Publication date: August 29, 2013Applicant: C. R. BARD, INC.Inventor: C. R. BARD, INC.
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Publication number: 20130225977Abstract: The present invention comprises systems, methods and devices for the delivery of visualizable or treatment compositions or therapeutic agents comprising device elements for diagnosis and/or treatment of conduits. A delivery system comprising an introducer shaft having at least one exit port sad at least one delivery catheter tor placement of compositions into the conduit, such as a fallopian tube.Type: ApplicationFiled: November 25, 2012Publication date: August 29, 2013Applicant: Femasys Inc.Inventor: Femasys Inc.
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Publication number: 20130225990Abstract: An access port for subcutaneous implantation is disclosed. Such an access port may comprise a body for capturing a septum for repeatedly inserting a needle therethrough into a cavity defined within the body. Further, the access port may include at least one feature structured and configured for identification of the access port subsequent to subcutaneous implantation. Methods of identifying a subcutaneously implanted access port are also disclosed. For example, a subcutaneously implanted access port may be provided and at least one feature of the subcutaneously implanted access port may be perceived. Further, the subcutaneously implanted access port may be identified in response to perceiving the at least one feature.Type: ApplicationFiled: March 29, 2013Publication date: August 29, 2013Applicant: C. R. BARD, INC.Inventor: C. R. BARD, INC.
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Patent number: 8506492Abstract: The invention relates to an ultrasound catheter comprising a device arranged in the area of the catheter tip for ultra-sound image recording, with at least one lumen routed into the area of the catheter tip open at this end and ending adjacent to the ultrasound image recording device for issuing an ultrasound contrast means being provided.Type: GrantFiled: April 26, 2006Date of Patent: August 13, 2013Assignee: Siemens AktiengesellschaftInventor: Michael Maschke
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Patent number: 8506493Abstract: The present invention is generally directed towards an imaging transducer assembly. Generally, the imaging transducer assembly is combined with a sensor of a medical positioning system. In one aspect, the transducer assembly and the sensor share the same voltage source. In another aspect of the invention, the sensor surrounds a portion of the imaging transducer assembly, forming a housing that reinforces the assembly.Type: GrantFiled: November 29, 2005Date of Patent: August 13, 2013Assignee: Scimed Life Systems, Inc.Inventor: Isaac Ostrovsky
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Patent number: 8478382Abstract: A method for displaying a position of a medical device, such as a catheter, during insertion of the medical device into a patient is disclosed. In one example embodiment, the method includes obtaining a first set of detected position data relating to a location marker, then determining a possible first position of the location marker. A first confidence level relating to a match between the first set of detected position data and a first set of predicted position data is assigned. A determination is made whether the first confidence level meets or exceeds a first threshold. If the first confidence level meets or exceeds the first threshold, a determination is then made whether the first position of the location marker is within a first detection zone. If the first position of the location marker is within the first detection zone, the first position of the location marker is displayed.Type: GrantFiled: February 11, 2009Date of Patent: July 2, 2013Assignee: C. R. Bard, Inc.Inventors: Eddie K. Burnside, Shayne Messerly, Robert N. Golden, Rand W. Lee
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Patent number: 8460214Abstract: A vascular guidewire system includes a tubular member which at least partially encloses a core wire. A first or distal gripper is connected with a handle to grip a proximal end portion of the tubular member. A second or proximal gripper is disposed in the handle and grips a proximal end portion of the core wire. A first or distal motor is disposed in the handle and is operable to rotate the core wire relative to the outer tubular member. A second or proximal motor is disposed in the handle and is operable to move the first or distal motor longitudinally relative to the handle to thereby move the core wire longitudinally relative to the outer tubular member. The second or proximal motor is disposed in a coaxial relationship with the first or distal motor. Rotational and/or longitudinally directed forces may be manually applied to the handle to move the tubular member and core wire relative to a patient's body.Type: GrantFiled: October 14, 2009Date of Patent: June 11, 2013Assignee: The Cleveland Clinic FoundationInventors: Barry D. Kuban, David R. Whittaker, Ryan S. Klatte
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Publication number: 20130131508Abstract: In one embodiment, a gas contamination detection apparatus includes a gas analyzer adapted to receive a sample of a gas to be delivered to a patient and to analyze the gas sample to determine whether the gas contains a contaminant, and a gas shut-off valve adapted to automatically prevent the gas from being delivered to the patient if the gas is determined to contain a contaminant.Type: ApplicationFiled: August 3, 2011Publication date: May 23, 2013Inventor: Ray Gerald Thomas
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Patent number: 8436615Abstract: A waveguide antenna assembly for a magnetic resonance tomography apparatus, particularly a waveguide antenna assembly that can be detuned for an operation with local coils, is composed of multiple metal surfaces connected by diodes respectively located between the metal surfaces. Only when the diodes are through-connected between these metal surfaces are the surfaces connected with one another in terms of RF signals via these diodes, so the assembly operates as a waveguide antenna. When the diodes are disabled between these metal surfaces, the surfaces are unconnected with one another for RF signals.Type: GrantFiled: July 8, 2010Date of Patent: May 7, 2013Assignee: Siemens AktiengesellschaftInventors: Wolfgang Renz, Karsten Wicklow
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Publication number: 20130096427Abstract: Embodiments include a fiducial deployment system including a needle and at least two adjacent and releasably-engaged fiducials retained within a lumen of the needle by engagement with each other and/or by engagement with a pusher element. A fiducial may include one or more mechanical engagement structures that interengage with and/or are rupturably attached to one or more adjacent fiducials. The needle, which may include echogenic enhancements, may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time. A variety of releasably-engaged fiducials are disclosed, as are methods for use.Type: ApplicationFiled: October 5, 2012Publication date: April 18, 2013Applicant: Cook Medical Technologies LLCInventor: Cook Medical Technologies LLC
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Patent number: 8403866Abstract: A method and apparatus for introducing a cardiac lead to an implantation site that includes a catheter body having an outer wall and a distal leader and having a proximal portion extending from the first proximal end to a second distal end. An inner member is positioned within an outer lumen of the catheter body and is spaced from the outer wall to form a first inner lumen for receiving a guide tool inserted therein and a second lumen for receiving the cardiac lead while the guide tool is positioned within the first inner lumen. A distal end of the inner member forms a first opening at a distal end of the first inner lumen and a second opening at a distal end of the second inner lumen, the first opening and the second opening positioned proximal the distal leader.Type: GrantFiled: April 14, 2009Date of Patent: March 26, 2013Assignee: Medtronic, Inc.Inventors: Kevin R. Seifert, Raymond Yee
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Patent number: 8391953Abstract: Apparatus for driving current in a power circuit of a medical device inserted into a body of a subject includes a power transmitter, which is adapted to generate, in a vicinity of the body, an electromagnetic field having a predetermined frequency capable of inductively driving the current in the power circuit. A passive energy transfer amplifier, having a resonant response at the frequency of the electromagnetic field is placed in proximity to the medical device so as to enhance the current driven in the power circuit by the electromagnetic field.Type: GrantFiled: October 6, 2009Date of Patent: March 5, 2013Assignee: Biosense Webster, Inc.Inventors: Assaf Govari, Michael Levin
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Patent number: 8391959Abstract: Method and composition suitable for administering by direct convective interstitial infusion are disclosed. The method comprises: placing at least one direct convective interstitial infusion catheter in contact with the tissue, and pressuring the composition through the catheter. The composition is in a liquefied form having a viscosity above a predetermined value. The predetermined value is selected so as to improve infusion of the compositions into interstitial volumes of the tissue, while minimizing backflow of the compositions along an outer wall of the catheter or leakage into low resistance paths. It is demonstrated that high viscosity results in higher treatment efficiency.Type: GrantFiled: September 29, 2005Date of Patent: March 5, 2013Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Medical Research Fund of Tel Aviv Sourasky Medical CenterInventors: Yael Mardor, Zvi Ram
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Publication number: 20130053693Abstract: A system for preventing air from entering a first catheter of a multi-catheter system. Air is prevented from entering the proximal end of the first catheter by an axially elongate chamber having an impeller, the chamber being affixed to the proximal end of the first catheter. The air is removed through a port near the centerline of the chamber. Liquid removed with the air is returned to the chamber to minimize liquid loss during the procedure. A second catheter inserted through the chamber and into the first catheter is unable to entrain gas into the first catheter because any gas that enters the chamber is routed to the centerline of the chamber where it is removed. Inflow of fluid from an external pump scrubs the second catheter shaft of air bubbles attached by surface tension.Type: ApplicationFiled: August 7, 2012Publication date: February 28, 2013Inventors: Eugene M. Breznock, Jay A. Lenker, David W. Wieting
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Patent number: 8371303Abstract: Described herein is an apparatus that includes an endotracheal tube or airway device having a proximal end and a distal end and an occlusion cuff. The occlusion cuff includes a sensor for helping determine proper endotracheal or airway device placement.Type: GrantFiled: August 5, 2010Date of Patent: February 12, 2013Assignee: Anesthetech Inc.Inventors: David Schaner, Harshvardhan N. Chaobal
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Patent number: 8371443Abstract: A biopsy marker delivery device are described. The delivery device can include a relatively flexible hollow tube, a pushing member such as a push rod disposed for sliding with the tube, and at least one marker disposed in the tube. A marker blocking member is disposed distal of the distal most marker, and is disposed at least partially within the hollow tube to assist in preventing premature deployment of a marker from the hollow tube. A portion of the blocking member may disposed in the hollow tube, and another portion of the member may be operatively associated with a portion of the package such that when the marker delivery device is removed from the package, the member is removed from the marker delivery device.Type: GrantFiled: September 22, 2009Date of Patent: February 12, 2013Assignee: Devicor Medical Products, Inc.Inventors: Andrew P. Nock, Ramon Ramos, Shailendra K. Parihar
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Patent number: 8359730Abstract: A surgical navigation system for navigating a region of a patient includes a non-invasive dynamic reference frame and/or fiducial marker, sensor tipped instruments, and isolator circuits. The dynamic reference frame may be repeatably placed on the patient in a precise location for guiding the instruments. The instruments may be precisely guided by positioning sensors near moveable portions of the instruments. Electrical sources may be electrically isolated from the patient.Type: GrantFiled: July 1, 2011Date of Patent: January 29, 2013Assignee: Medtronic Navigation, Inc.Inventors: Bruce M. Burg, John H. Dukesherer, Bradley A. Jascob, Paul Kessman
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Patent number: 8364245Abstract: A system includes a component that updates a registration between an image space coordinate system and an interventional space coordinate system. The registration update is based on interventional device position information within a patient obtained from intermediate image data indicative of the interventional device location and a position sensor that is located on an interventional device within the patient.Type: GrantFiled: May 11, 2007Date of Patent: January 29, 2013Assignee: Koninklijke Philips Electronics N.V.Inventor: Jochen Kruecker
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Publication number: 20130018258Abstract: An endoprosthesis (e.g., a sleeve) can be used to deliver therapeutic agents to vascular dissections or perforations. The sleeve can have a tissue adhesive and a drug-eluting biodegradable substrate layer.Type: ApplicationFiled: June 27, 2012Publication date: January 17, 2013Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Martyn Folan, Fergal Horgan, Marie Turkington
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Publication number: 20130018259Abstract: An intralumenal marker that includes an atraumatic anchoring portion that allows the marker to be fixed within a body lumen, such as an airway, without risk of migration. The anchoring portion may be an elongate body that reassumes a relaxed, coiled configuration after being delivered from a catheter. A body portion is attached to the anchoring portion and provides a function such as radiopaque marking, drug delivery, illumination, or the like.Type: ApplicationFiled: June 28, 2012Publication date: January 17, 2013Inventors: Thomas Borillo, Jerone Kent Grudem, JR.
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Patent number: 8308726Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.Type: GrantFiled: September 1, 2005Date of Patent: November 13, 2012Inventors: Atul Kumar, Alka Kumar
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Patent number: 8311304Abstract: A method for detecting tubing in a radiographic image of a patient, executed at least in part by a control logic processor, obtains a radiographic image data for a patient and detects one or more possible tube segments in the image. At least one tubing candidate is formed by growing at least one detected tube segment or merging two or more detected tube segments.Type: GrantFiled: November 15, 2011Date of Patent: November 13, 2012Assignee: Carestream Health, Inc.Inventor: Zhimin Huo
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Patent number: 8298160Abstract: Apparatus for use in deploying medical devices. The apparatus includes a wire having a diameter such that the wire can appropriately be used with either a corresponding over-the-wire configured catheter or a rapid-exchange configured catheter. The wire has a location at which it can be easily fractured, when desired, in order to convert the length of the wire from a length for use in an over-the-wire configuration to a rapid-exchange configuration.Type: GrantFiled: March 14, 2002Date of Patent: October 30, 2012Assignee: EV3 Inc.Inventors: John C. Oslund, Patrick P. Russo
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Patent number: 8290572Abstract: A system for and method of determining and compensating for the effect of a field influencing object on a field sensor, preferably a coil, that is within a navigational domain. The navigational domain contains navigational magnetic energy and disturbing magnetic energy, and the field influencing object produces the disturbing magnetic energy in response to the navigational magnetic energy. The correction system includes a first transmitter for projecting into the navigational domain field energy in a first waveform sufficient to induce a first signal value in the sensing coil. The system also includes a second transmitter for projecting into the navigational domain field energy in a second waveform sufficient to induce a second signal value in the sensing coil. The system further includes a signal processor for receiving the first signal value and for receiving the second signal value to determine the effect of the electrically conductive object on the field sensor.Type: GrantFiled: September 13, 2010Date of Patent: October 16, 2012Assignee: Medtronic Navigation, Inc.Inventors: Michael A. Martinelli, Paul Kessman, Bradley A. Jascob
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Patent number: 8271068Abstract: A method of determining a three-dimensional (3D) position of a catheter tip includes: compensating a 2D position of the tip of the catheter for respiratory motion to generate a compensated 2D catheter position, generating weighted sample points around the compensated 2D catheter position, determining correspondent points of the weighted sample points in a 3D image, computing a weighted mean and a weighted covariance of each correspondent point, and determining the 3D position of the catheter tip in the 3D image from a fusion of the weighted means and weighted covariances.Type: GrantFiled: October 1, 2008Date of Patent: September 18, 2012Assignee: Siemens AktiengesellschaftInventors: Ali Khamene, Frederik Bender, Wolfgang Wein
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Patent number: 8239003Abstract: A system and method of integrating electromagnetic microsensors into interventional endovascular devices such as guidewires for tracking guidewires within vessels of the body with the use of a surgical navigation system.Type: GrantFiled: April 16, 2007Date of Patent: August 7, 2012Assignee: General Electric CompanyInventor: Samuel Joseph Akins
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Patent number: 8233967Abstract: A method is disclosed for marking and visualizing an implant by use of an x-ray phase-contrast tomography examination. Further, an implant is also disclosed. In at least one embodiment, implants are used with specific characteristics which are as unambiguous as possible with regard to the phase shift generated by the implants in a phase-contrast tomography examination. In at least one embodiment, these specific characteristics can include the typical self-generated specific phase shift, typical differences in the specific phase-shift values, or typical spatial structures of materials with well-defined phase-shift values.Type: GrantFiled: August 11, 2008Date of Patent: July 31, 2012Assignee: Siemens AktiengesellschaftInventors: Eckhard Hempel, Martin Hoheisel, Stefan Popescu, Rainer Raupach