Abstract: Rotational shape-memory actuators and associated devices, systems, and methods are disclosed. In some embodiments, a rotational shape-memory actuator includes a first anchor, a second anchor, a spring element extending between the first and second anchors, a first shape memory element extending between the first and second anchors, a second shape memory element extending between the first and second anchors, and a communication line wrapped around the first and second shape memory elements. The first and second shape memory elements are configured to transition between a first configuration in which the first and second shape memory elements are twisted together and a second configuration in which the first and second shape memory elements are less twisted together such that transitions of the first and second shape memory elements between the first and second configurations cause the second anchor to rotate with respect to the first anchor.

Abstract: Methods for processing two-dimensional ultrasound images from an intracardiac ultrasound imaging catheter provide improved image quality and enable generating three-dimensional composite images of the heart. Two-dimensional ultrasound images are obtained and stored in conjunction with correlating information, such as time or an electrocardiogram. Images related to particular conditions or configurations of the heart can be processed in combination to reduce image noise and increase resolution. Images may be processed to recognize structure edges, and the location of structure edges used to generate cartoon rendered images of the structure. Structure locations may be averaged over several images to remove noise, distortions and blurring from movement.

Abstract: Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

Abstract: A method including positioning a delivery device at a location in a blood vessel; advancing the delivery device a distance into a wall of the blood vessel to a treatment site beyond an external elastic lamina of the blood vessel; and after advancing the delivery device, introducing a treatment agent including a cellular component through the delivery device. A composition including a treatment agent comprising a cellular component associated with a matrix material, wherein the composition is suitable for percutaneous delivery. Also an apparatus suitable for delivering a treatment agent. Also, a kit including a treatment agent.

Abstract: Methods of using the device for conducting business transactions are also included. An impedance spectroscopy system for monitoring ischemic mucosal damage in hollow viscous organs comprises a sensor catheter and an impedance spectrometer for electrically driving the catheter to obtain a complex tissue impedance spectrum. Once the catheter is in place in one of a patient's hollow viscous organs, the impedance spectrometer obtains the complex impedance spectrum by causing two electrodes in the tip of the catheter to inject a current into the mucosal tissue at different frequencies, while two other electrodes measure the resulting voltages. A pattern recognition system is then used to analyze the complex impedance spectrum and to quantify the severity of the mucosal injury. Alternatively, the complex impedance spectrum can be appropriately plotted against the spectrum of normal tissue, allowing for a visual comparison by trained personnel.

Abstract: A catheter system adapted for navigating, guiding and implanting a catheter or a plurality of catheters in a spatially-defined implantation within the tissue of a patient is provided. The system can include a tissue navigation system and a probe to inform the navigation system to guide emplacement of the catheters within a target tissue. The probe can provide images, such as fiberoptic visual images, or ultrasound images, or can provide radiolocation data, to guide the catheter emplacement. The catheters supply a pressurized liquid including a bioactive agent, such as can be used in the treatment of cancer, for example 123I- or 125I-IUDR. The system and methods provided can be used in the treatment of locally advanced tumors, such as cancers of the brain, head or neck, esophagus, prostate, ovary, liver, pancreas, bladder or rectum.

Abstract: A rotational intravascular ultrasound probe for insertion into a vasculature and a method of manufacturing the same. The rotational intravascular ultrasound probe comprises an elongate catheter having a flexible body and an elongate transducer shaft disposed within the flexible body. The transducer shaft comprises a proximal end portion, a distal end portion, a drive shaft extending from the proximal end portion to the distal end portion, an ultrasonic transducer disposed near the distal end portion for obtaining a circumferential image through rotation, and a transducer housing molded to the drive shaft and the ultrasonic transducer.

Abstract: An ultrasound device including an ultrasonic transducer device having a plurality of transducer elements forming a transducer array is provided. Each transducer element includes a piezoelectric material disposed between a first electrode and a second electrode. One of the first and second electrodes is a ground electrode and the other of the first and second electrodes is a signal electrode. The ultrasound device further includes a cable assembly having a plurality of connective signal elements and a plurality of connective ground elements extending in substantially parallel relation therealong. Each connective element is configured to form an electrically-conductive engagement with respective ones of the signal electrodes and the ground electrodes of the transducer elements in the transducer array. The connective ground elements are alternatingly disposed with the connective signal elements across the cable assembly, to provide shielding between the connective signal elements.

Abstract: A method and apparatus directed to formation of a connection with an ultrasonic transducer apparatus (UTA) comprising a transducer device having first and second electrodes is provided. The UTA is engaged with an interposer device surface. The interposer device is greater in at least one lateral dimension than and extends laterally outward of the UTA, and comprises at least two laterally-extending conductors. A conductive engagement is formed between the first and second electrodes and respective first ends of the conductors. A connection support substrate is engaged with the interposer device about second ends of the conductors, and includes at least two connective elements for forming a conductive engagement with the respective second ends of the conductors. The UTA is then inserted into a catheter member lumen such that the device plane of the UTA and the at least two connective elements extend axially along the lumen.

Abstract: An ultrasound catheter probe assembly capable of scanning a three-dimensional volume is provided. The ultrasound catheter probe assembly contains a plurality of ultrasonic transducers disposed along a central axis of the ultrasound catheter probe assembly. The plurality of ultrasonic transducers is disposed on a mechanism operable to reciprocally pivot the plurality of ultrasonic transducers enabling the plurality of ultrasonic transducers to scan a three-dimensional volume. A helically disposed electrical interconnection member may be disposed about a pivot axis of the plurality of ultrasonic transducers and may electrically interconnect the plurality of ultrasonic transducers to an ultrasound imaging system. The ultrasound transducer catheter probe assembly may be fluid-filled and contain bubble position control and fluid expansion compensation features.

Abstract: A method, including constructing a simulated surface of a body cavity, and pressing a distal end of a probe against a wall of the body cavity. While pressing the distal end against the wall, position measurements are accepted from the probe indicating a position of the probe within the body cavity, and force measurements are accepted from the probe indicating a force between the distal end and the wall. A distortion in the simulated surface is created at the position indicated by the position measurements, so as to form a distorted surface, upon detecting that the force measurements exceed a predefined amount. The distorted surface is then displayed.

Abstract: An interventional medical device is provided that incorporates a forward-directed ultrasound imaging system integrated into a single minimally invasive device. The medical device can be in the form of catheters and interventional devices having a tapered distal tip, particularly those suitable for minimally invasive direct introduction into the human or other mammalian body. The imaging system comprises one or more small ultrasound transducers that can be permanently integrated into the device or integrated into an interchangeable ultrasound transducer that may be inserted into and removed from the device to customize the device for a particular use. An ultrasound system can be provided in the device either alone or in combination with fiber optic imaging to provide a range of forward imaging and therapeutic capabilities of the device for direct access to a target site from the skin via an introducer needle.

Abstract: The invention relates to an ultrasound catheter comprising a device arranged in the area of the catheter tip for ultra-sound image recording, with at least one lumen routed into the area of the catheter tip open at this end and ending adjacent to the ultrasound image recording device for issuing an ultrasound contrast means being provided.

Abstract: The present invention is generally directed towards an imaging transducer assembly. Generally, the imaging transducer assembly is combined with a sensor of a medical positioning system. In one aspect, the transducer assembly and the sensor share the same voltage source. In another aspect of the invention, the sensor surrounds a portion of the imaging transducer assembly, forming a housing that reinforces the assembly.

Abstract: An ultrasound catheter probe assembly capable of scanning a three-dimensional volume is provided. The ultrasound catheter probe assembly contains a plurality of ultrasonic transducers disposed along a central axis of the ultrasound catheter probe assembly. The plurality of ultrasonic transducers is disposed on a mechanism operable to reciprocally pivot the plurality of ultrasonic transducers enabling the plurality of ultrasonic transducers to scan a three-dimensional volume. A helically disposed electrical interconnection member may be disposed about a pivot axis of the plurality of ultrasonic transducers and may electrically interconnect the plurality of ultrasonic transducers to an ultrasound imaging system. The ultrasound transducer catheter probe assembly may be fluid-filled and contain bubble position control and fluid expansion compensation features.

Abstract: The systems and methods described herein provide for a forward looking guidewire having a reduced radial cross-section for increased maneuverability and use of the guidewire within more narrow vasculature. The guidewire can include an elongate tubular member having a distal region, proximal region and inner lumen and a forward looking imaging device coupled with the distal end of the guidewire. The distal region of the guidewire can be relatively more flexible than the proximal region. The guidewire can also include a second, side looking imaging device, which can be coupled around a longitudinal portion of the guidewire in the radial or proximal regions.

Abstract: An intravascular ultrasound catheter system is provided and enables a simplified, economical technique for ultrasound visualization of a blood vessel. The catheter may include a park ablation system for crossing chronic total occlusions and severe stenoses. The catheter is advanceable and is oriented entirely under manual control of the clinician and the application of radiofrequency energy for spark erosion of the stenosis also is controlled manually by the clinician. The system enables the clinician to observe an ultrasound image sufficiently to determine where to orient the ablation electrode so as to reduce the risk of dissection or perforation of the blood vessel. The ultrasound image is generated in response to manual rotation of the catheter and the ablation spark is generated only when the physician is satisfied as to the orientation of the electrode within the vessel.

Abstract: A RF ablation device includes a probe assembly that has an elongate cannula having a lumen disposed interiorly of an external wall of the cannula. The elongate cannula includes a plurality of slots formed within the external wall that provide access to the lumen. The probe assembly includes an electrode member that is slidably disposed within the elongate cannula, the electrode member including a plurality of tines configured for passage through the plurality of slots. The slots are disposed in a staggered arrangement or pattern about the external wall of the cannula. The staggered arrangement of slots may be used in a monopolar or bipolar arrangement of the electrodes on the cannula. A bipolar arrangement of electrodes using the staggered configuration produces larger ablation areas in a shorter period of time as compared to prior designs.

Abstract: Automated image interpretation is provided with transducer position and/or orientation sensing. The current position of a transducer is used to determine the anatomy being imaged. Other reference information, such as (1) the previous position of the transducer and the known anatomy being imaged at that time or (2) a reference device at a known location, is used in the determination. The anatomy is determined based on position sensing or determined based on position sensing and other anatomy features, such as image analysis.

Abstract: An expandable member for characterizing a three-dimensional space within a mammalian body is described. The expandable member is delivered to a target region in a deflated state where it is expanded by inflation of the member. Sensory transducers that contact the member relay sensory information generated when the member is in an expanded state to a microprocessor located outside the body. Using the sensory information, a data-driven picture that characterizes the three-dimensional space within the body is created with a microprocessor. The apparatus is useful in preparation for minimally invasive surgical therapy.

Abstract: The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.

Abstract: Intravascular ultrasound techniques provide for intravascular imaging using contrast agents and nonlinear techniques. An ultrasound imaging device for detecting internal properties of a target body comprises an ultrasound transducer positioned at a distal end portion of a catheter, for transmitting excitation pulses and for receiving echo signals. A signal processor analyses echo signals at harmonics and/or subharmonics of the transmit frequency. The catheter may include a contrast agent delivery conduit extending along the catheter, the delivery conduit having an exit orifice proximal to the ultrasound transducer. The device may discriminate between echo signals respectively arising from interaction with tissue and from the interaction with contrast agent. The device may generate an image of the site of interest using non-linear components of the received ultrasound echo signals.

Abstract: An ultrasound endoscope includes an objective optical system, an illumination optical system, a distal end portion, an ultrasound transducer portion, a distal end cover, a through-hole formed in the distal end cover, a conductor wire portion, and a conductor wire portion passing portion formed in the distal end cover and configured to communicate with the through-hole and reach an outer circumference of the distal end cover, the conductor wire portion passing portion forming a region where the conductor wire portion passes from the through-hole to an outside of the distal end cover member when the ultrasound transducer portion is detached from the distal end portion.

Abstract: In an ultrasonic diagnostic apparatus using an ultrasonic probe of a mechanical radial scanning type for intracavity observation, stable Doppler mode images with respect to an ROI or a gate position can be generated by reducing an influence of uneven rotation of a flexible shaft. The apparatus includes: a signal processing unit for performing orthogonal detection processing or orthogonal sampling processing on a reception signal to generate a complex baseband signal; a memory for storing the complex baseband signal for at least two frames generated based on ultrasonic echoes received along plural lines; a line selecting unit for selecting one line in each frame from among the plural lines based on the complex baseband signal; and an image signal generating unit for generating an image signal representing information on blood flow based on the complex baseband signal with reference to the line selected in each frame.

Abstract: A system and method are provided for significantly reducing or substantially eliminating angular geometric distortions in devices designed for imaging and/or inspection of an interior portion or surface of a cavity. A series of processing steps or methods may be employed to eliminate Non-Uniform Rotational Distortion (NURD) in such devices, for example, unidirectional and bi-directional intravascular ultrasonic (IVUS) imaging systems. The system may include a processor and an electronic module which control operation of a transducer assembly provided at a distal end of a catheter assembly. The system invokes a first processing step or method to collect and store raw angle and line data, as well as one or more of second and third processing steps or methods which adjust for NURD experienced during backlash of a bi-directional imaging system and a fourth processing step or method which performs a line-to-line correlation function.

Abstract: An interventional medical device is provided that incorporates a forward-directed ultrasound imaging system integrated into a single device. The medical device can be in the form of sheaths, catheters, and interventional devices, particularly those suitable for minimally invasive procedures in the human or other mammalian body. The imaging system comprises one or more small ultrasound transducers that can be permanently integrated into the device or integrated into an interchangeable ultrasound transducer that can be inserted into and removed from the device to customize the device for a particular use. An ultrasound system can be provided in the device either alone or in combination with fiber optic imaging to provide a range of imaging and therapeutic capabilities of the device.

Abstract: An intravascular ultrasound probe is disclosed, incorporating features for utilizing an advanced transducer technology on a rotating transducer shaft. In particular, the probe accommodates the transmission of the multitude of signals across the boundary between the rotary and stationary components of the probe required to support an advanced transducer technology. These advanced transducer technologies offer the potential for increased bandwidth, improved beam profiles, better signal to noise ratio, reduced manufacturing costs, advanced tissue characterization algorithms, and other desirable features. Furthermore, the inclusion of electronic components on the spinning side of the probe can be highly advantageous in terms of preserving maximum signal to noise ratio and signal fidelity, along with other performance benefits.

Abstract: An interventional medical device that incorporates an imaging system may be minimally invasive and equipped with an anchoring portion at a proximal end for securing the device to a human body. A luer lock may be utilized at the proximal end, for example, for introducing a syringe. The medical device can be in the form of sheaths, catheters, and interventional devices, particularly those suitable for minimally invasive procedures in the pericardium. The imaging system comprises one or more ultrasound transducers and can be used to guide the device to a target area and to perform a procedure and/or provide access to a target area for performing a procedure via a plurality of lumen. In one embodiment, a micro-electro-mechanical system may be utilized to monitor pressure within a human body.

Abstract: Harmonic capacitive micromachined ultrasonic transducer (“cMUT”) devices and fabrication methods are provided. In a preferred embodiment, a harmonic cMUT device generally comprises a membrane having a non-uniform mass distribution. A mass load positioned along the membrane can be utilized to alter the mass distribution of the membrane. The mass load can be a part of the membrane and formed of the same material or a different material as the membrane. The mass load can be positioned to correspond with a vibration mode of the membrane, and also to adjust or shift a vibration mode of the membrane. The mass load can also be positioned at predetermined locations along the membrane to control the harmonic vibrations of the membrane. A cMUT can also comprise a cavity defined by the membrane, a first electrode proximate the membrane, and a second electrode proximate a substrate. Other embodiments are also claimed and described.

Abstract: Described herein is an apparatus that includes an endotracheal tube or airway device having a proximal end and a distal end and an occlusion cuff. The occlusion cuff includes a sensor for helping determine proper endotracheal or airway device placement.

Abstract: Asymmetric membrane capacitive micromachined ultrasonic transducer (“cMUT”) devices and fabrication methods are provided. In a preferred embodiment, a cMUT device according to the present invention generally comprises a membrane having asymmetric properties. The membrane can have a varied width across its length so that its ends have different widths. The asymmetric membrane can have varied flex characteristics due to its varied width dimensions. In another preferred embodiment, a cMUT device according to the present invention generally comprises an electrode element having asymmetric properties. The electrode element can have a varied width across its length so that its ends have different widths. The asymmetric electrode element can have different reception and transmission characteristics due to its varied width dimensions. In another preferred embodiment, a mass load positioned along the membrane can alter the mass distribution of the membrane. Other embodiments are also claimed and described.

Abstract: An anorectal probe assembly comprising an anorectal probe, a sonar penetration balloon mounted to said probe, said balloon arranged to receive water to inflate within the rectal cavity a sigmoidscope having a bore into which the probe and balloon have sliding engagement and an adaptor having an anus penetration portion for insertion into the anus and an external portion mounted to the penetration portion wherein the adaptor includes a conduit extending from the penetration portion to the external portion such that on penetration of the anus, the conduit provides fluid communication between the rectal cavity and the external portion, said conduit further connectable to a vacuum source.

Abstract: A device and a method for sealing a micromotor with an optional associated gearbox are disclosed where, in one aspect of the present invention, a catheter tip comprises: a micromotor; an ultrasound imaging transducer; a gearbox mechanically coupled to the micromotor, the gearbox having a rotatable portion mechanically coupled to the ultrasound imaging transducer array; and a moisture barrier disposed so as to reduce or prevent acoustic coupling fluid from entering both the gearbox and the micromotor.

Abstract: An ultrasound probe includes a transducer which is pivotally mounted inside a fluid chamber for scanning a region outside the probe as the transducer is oscillated. A volume compensation balloon is attached to the fluid chamber and is partially filled with acoustic fluid at nominal (room) temperatures. The balloon is made of a high performance thermoplastic which enables the balloon to have a very thin wall. The thin wall is highly compliant as the volume of the fluid inside the balloon changes, and remains so at low temperatures of transport and use. The thin wall exhibits a low permeability to the acoustic fluid. The balloon is formed of a non elastic material and exhibits good thermal stability and high burst strength.

Abstract: A method of scanning breast tissue involves inserting an imaging element into a breast via a carrier inserted into a breast duct. The imaging element may be for example a receiver, a transmitter or a mirror. A signal is transmitted between one imaging element within the breast duct and a second imaging element outside the breast.

Abstract: Catheter navigation is coupled with ultrasound imaging to yield a context map showing the location on a heart of the ultrasonically imaged frame.

Abstract: An ultrasound medical treatment system includes an end effector insertable into a patient. The end effector includes a tissue-retaining device. The tissue-retaining device includes a first tissue-retaining member having an ultrasound medical-treatment transducer and includes a second tissue-retaining member. The first and second tissue-retaining members are operatively connected together to retain patient tissue between the first and second tissue-retaining members and to release patient tissue so retained. In one example, the second tissue-retaining member has an ultrasound reflector. In the same or a different example, the ultrasound medical-treatment transducer is an ultrasound imaging and medical-treatment transducer.

Abstract: Described herein are imaging catheter system. In an exemplary embodiment, a catheter comprises a handle assembly having distal and proximal ends, a catheter sheath connected to the distal end of the handle assembly, and an elongated flexible tube connected to the proximal end of the handle assembly. The catheter further comprises an imaging core slidably received within the catheter sheath, the handle assembly and the elongated tube. The imaging core also includes a slide member, e.g., knob, extending from the imaging core and passing through an elongated slot in the handle assembly, allowing a physician to manually pullback and advance the imaging core within the catheter by sliding the slide member back and forth. Preferably, the elongated tube is long enough so that the motor drive coupled to the proximal end of the catheter is kept outside the sterile field during the imaging procedure.

Abstract: An ultrasound catheter assembly having a rotatable transducer assembly is disclosed. The ultrasound catheter assembly includes an elongate flexible shaft having a lumen and a proximal end and a distal end. The catheter assembly further includes a drive member that engages the transducer assembly at a distal end of the catheter. Rotation of the drive member in a first direction causes the transducer assembly to rotate in an oscillatory fashion in a second direction.

Abstract: A hand-held apparatus can be used to assist in guiding a probe or locating a particular anatomical target in a subject. The apparatus can include an ultrasonic transducer located on or within a housing and configured to generate ultrasonic energy directed into tissue of a subject and configured to receive a portion of the ultrasonic energy reflected by a target located within the tissue. In an example, the apparatus can include a motion tracking circuit configured to provide information indicative of a motion of the hand-held apparatus to the processor circuit, and a display configured to present information about a location of the target with respect to a portion of the hand-held apparatus, the information about the location determined by the processor circuit using the obtained information indicative of the ultrasonic energy reflected by the target and the information indicative of the motion of the hand-held apparatus.

Abstract: The present invention generally relates to medical devices, and more particularly to an improved medical imaging device. In one embodiment, an imaging device includes a drive shaft having proximal and distal ends received within the lumen; an imaging transducer coupled to the distal end of the drive shaft and positioned at the distal portion of the elongate member; and a flow detector coupled to the imaging transducer. The flow detector may include a forward facing ultrasound transducer configured to emit energy in the direction of the longitudinal axis of the imaging device and detect a Doppler shift in the received echoes. In the case where the imaging device is located in a vessel having blood flow, such information may be used to calculate the velocity of the blood flow. The imaging device may be configured to be located in a catheter or guidewire.

Abstract: A method and system are disclosed for creating, in a coordinated manner, graphical images of a body including vascular features from a combination of image data sources. The method includes initially creating an angiographic image of a vessel segment. The angiographic image is, for example, either a two or three dimensional image representation. Next, a vessel image data set is acquired that is distinct from the angiographic image data. The vessel image data set comprises information acquired at a series of positions along the vessel segment. An example of such vessel image data is a set of intravascular ultrasound frames corresponding to circumferential cross-section slices taken at various positions along the vessel segment. The angiographic image and the vessel image data set are correlated by comparing a characteristic rendered independently from both the angiographic image and the vessel image data at positions along the vessel segment.

Abstract: The present invention relates to the diagnosis and treatment of stress urinary incontinence. In one embodiment, the diagnosis and treatment involves the use of a positional feedback catheter. Positional sensors may be embedded in the catheter to provide real-time tracking of the position and movement of the catheter.

Abstract: A medical device removal system includes a vessel filter repositioning or removal device to remove and/or reposition a medical device, such as a vessel filter. The system includes a gripper to grip a medical device that is located within a body vessel, and a detector, linked to the gripper, to detect the proximity of the medical device to the gripper. The system may also include an output to indicate a signal from the detector.

Abstract: An improved catheter is provided. The catheter may include a deflectable member located at a distal end of the catheter. The deflectable member may comprise an ultrasound transducer array. The catheter may include a lumen extending from a proximal end of the catheter to the distal end. The lumen may be used to deliver an interventional device to a point distal to the distal end of the catheter. The deflectable member may be selectively deflectable in a pivot-like manner through an arc of at least 90 degrees. In embodiments where the deflectable member includes an ultrasound transducer array, the ultrasound transducer array may be operable to image both when aligned with the catheter and when pivoted relative to the catheter. When pivoted relative to the catheter, the ultrasound transducer array may have a field of view distal to the distal end of the catheter.

Abstract: Shape-controllable catheters are provided that are versatile in application and that, in human-imaging applications, minimize or reduce patient discomfort. One such catheter is provided with at least one control wire that extends inside the catheter and a control mechanism for tensioning the control wire to produce in the catheter a humped shape or a cantilevered configuration. Hardness of the catheter may be varied along the length thereof to facilitate desired bending. For example, hardness may be reduced in bend areas. Hardness may be maintained or increased in other areas for performance reasons, for example to maintain planarity of an imaging array.

Abstract: An ultrasonic imaging tube is provided. A tube body has a longitudinal axis and a circumference. A first transducer array is disposed in the body along the longitudinal axis. A second transducer array is disposed in the body along the longitudinal axis. The first transducer array is substantially parallel with the second transducer array. The first transducer array and the second transducer array are at a first non-zero angle to each other about the longitudinal axis.

Abstract: Devices and methods are disclosed for providing a sensing element to scan tissue and detect the presence of structures within the tissue to avoid the structures when performing a procedure on the tissue. A catheter includes a blood vessel sensing assembly and a working lumen adapted to receive a medical appliance or instrument for performing various medical procedures.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: When transesophageal echocardiography is used to obtain a transgastric short axis view of the left ventricle of the heart, the best place to position the transducer is in the fundus of the stomach, aimed up through the left ventricle. The probes disclosed herein facilitate placement of the transducer in the optimum position within the fundus, despite wide variations in the distance between the lower esophageal sphincter and the fundus among different subjects. In one preferred embodiment, the ultrasound probe uses a bending section with a series of vertebrae and stiffening that is more flexible proximally and less flexible distally, which causes the probe to bend relatively sharply at the point where the probe exits the lower esophageal sphincter. The flexibility of the proximal-most portion of the bending section is preferably greater than or equal to the flexibility of the interface between the bending section and the shaft.