Abstract: A plethysmograph variability processor inputs a plethysmograph waveform having pulses corresponding to pulsatile blood flow within a tissue site. The processor derives plethysmograph values based upon selected plethysmograph features, determines variability values, and calculates a plethysmograph variability parameter. The variability values indicate the variability of the plethysmograph features. The plethysmograph variability parameter is representative of the variability values and provides a useful indication of various physiological conditions and the efficacy of treatment for those conditions.

Abstract: There is provided an image detecting system including an image detecting section that detects a moving image of an examination subject into which a radiopaque contrast medium flows through one of an artery and a portal vein, and a change image generating section that generates a change image representing a change in the moving image. Here, the change is caused by movement of the radiopaque contrast medium after a timing at which the radiopaque contrast medium that has flown into one of the artery and the portal vein flows into capillaries.

Abstract: A system level scheme for networking of implantable devices, electronic patch devices/sensors coupled to the body, and wearable sensors/devices with cellular telephone/mobile devices, peripheral devices and remote servers is described.

Abstract: A method for producing a computational flow dynamics model for assessing the efficacy of the deployment of a flow-diverting device in a blood vessel of a patient is provided. Image data of the patient is acquired with a medical imaging system, from which images depicting the blood vessel are reconstructed. A pre-treatment blood vessel model is generated by segmenting the reconstructed images. This pre-treatment blood vessel model is then used to generate a post-treatment, or post-deployment, model of the blood vessel. A post-deployment model of the flow-diverting device is generated and used together with the post-treatment blood vessel model to generate a computational flow dynamics model.

Abstract: The present invention relates to an ear-carrying heart beat detection device, which includes a device body, an attaching structure, an ear clip, an extension assembly, a control circuit and a wrist watch unit. The attaching structure is coupled to the device body. The ear clip includes a blood flowrate sensor to detect variation of blood flowrate through a user's earlobe. The extension assembly adjusts the relative distance of the ear clip with respect to the device body. The control circuit is arranged inside the device body and the control circuit transmits a heart beat signal to a wrist watch unit in a wireless manner to allow the user to inspect the condition of heart beat of his or her body and to adjust the time period and style of exercise according to the heart beat information.

Abstract: Non-invasive systems and methods for determining fractional flow reserve. At least one method of determining fractional flow reserve within a luminal organ of the present disclosure comprising the steps of positioning a monitoring device external to a luminal organ and near a stenosis, the monitoring device capable of determining at least one characteristic of the stenosis, operating the monitoring device to determine the at least one characteristic of the stenosis, and determining fractional flow reserve at or near the stenosis based upon the at least one characteristic determined by the monitoring device.

Abstract: A graphical method of displaying interrelated blood pressure data that effectively communicates patient or group performance within or between discrete datasets. The graphical method displays Systolic Pressure (SP), Diastolic Pressure (DP), Pulse Pressure (PP), Mean Arterial Pressure (MAP) and the Classification of Blood Pressure as related to a single data point or a plurality of data points from a discrete dataset. Multiple datasets can be simultaneously displayed for comparison purposes allowing patients, physicians or scientists to understand the relative differences in dataset performance across a series of datasets.

Abstract: A technique is provided for computing or monitoring blood viscosity. The technique includes measuring a cross sectional area of a arterial segment and a volumetric flow rate of blood flowing through the arterial segment at two or more locations, estimating a compliance transfer function from blood measurements to scale the arterial cross sectional area into a pressure waveform, deriving a transmission line model of the arterial segment based on the cross sectional area, as scaled by the compliance transfer function, of the arterial segment at the two or more locations and the volumetric flow rate of blood at the two or more locations. The technique also includes computing the blood viscosity based on the transmission line model.

Abstract: A method of calculating blood flow in an organ of a subject using output radiofrequency signals transmitted to the organ and input radiofrequency signals received from the organ, the method comprises determining a phase shift of the input radiofrequency signals relative to the output radiofrequency signals and using the phase shift to calculate the blood flow in the organ.

Abstract: A photoplethysmography apparatus and method is provided for high resolution estimating of Time-Frequency Spectra (TFS) and associated amplitudes using Variable Frequency Complex Demodulation (VFCDM), in a two-step procedure using a Time-Varying Optimal Parameter Search (TVOPS) technique to obtain TFS, followed by VFCDM to obtain even greater TFS resolution and instantaneous amplitudes associated with only specific frequencies of interest, via the combined TVOPS and VFCDM.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: A method is disclosed for implementing an imaging examination method. In at least one embodiment, the method includes creating an overview data record containing angiography data relating to a patient; simulating flow conditions in vessels of the patient; determining a strain on the vascular walls with the aid of the simulation; identifying vascular regions, in which the strain on the vascular wall exceeds a threshold value and implementing an imaging examination in at least one of the identified vascular regions.

Abstract: User interfaces for medical perfusion systems that provide oxygenation, filtering, and recirculation of blood in connection with various medical procedures are provided. In particular, methods of displaying and communicating a desired target flow rate and cardiac index during cardiopulmonary bypass surgeries are provided.

Abstract: A method of detecting a suicide terrorist, comprises: (A) selecting a test subject; (B) installing a testing device that can detect real-time variations in cerebral blood flows at a first tested area and second tested area of the subject, wherein the first tested area corresponds to a suicide intent area of a cortex, and the second tested area corresponds to a negative response area of the cortex; (C) using the testing device to detect cortex activity information related to the cerebral blood flow variations of the first tested area within a predetermined time; (D) comparing the cortex activity information with a control group associated with normal individuals to obtain a result; (E) according to the result of step (D), determining whether the subject has suicide intent; (F)asking whether the subject is a terrorist; (G) using the testing device to detect a cortex activity information related to the cerebral blood flow variations of the second tested area within a predetermined time to obtain a result; and (H

Abstract: A method for measuring blood flow velocity comprises: placing a first and second blood vessel signal detectors on a body of a person to be measured in such a manner that the first and second blood vessel signal detectors are located a predetermined distance from each other; amplifying blood signal detected by the first and second blood vessel signal detectors; using the first and second blood vessel signal analyzers to record the blood signal at a predetermined time interval; setting an interval of time from the moment a specific blood vessel signal appears in a record of the first blood vessel signal analyzer to the moment the specific blood vessel signal appears in a record of the second blood vessel signal analyzer to be a predetermined time period; and dividing a value of the predetermined distance by a value of the predetermined time period can get a blood flow velocity.

Abstract: A device in an apparatus for extracorporeal blood treatment is configured to monitor a fluid flow rate (Q) of a cardiovascular system of a subject. The apparatus comprises an extracorporeal blood circuit and a connection (C) for connecting the extracorporeal blood circuit to the cardiovascular system. The device comprises an input for obtaining a time-dependent measurement signal (d(n)) from a pressure sensor in the extracorporeal blood circuit. The pressure sensor is arranged to detect a subject pulse originating from a subject pulse generator in the cardiovascular system of the subject, wherein the system further comprises a signal processor connected to the input. The signal processor is configured to process the measurement signal to obtain a pulse profile (e(n)) which is a temporal signal profile of the subject pulse, and to calculate a fluid flow rate (Q) based at least partly on the temporal signal profile.

Abstract: A method of analysis is disclosed. The method comprises receiving a non-ECG signal indicative of heart beats of a sleeping subject; extracting from the signal a series of inter-beat intervals (IBI); calculating at least one Poincare parameter characterizing a Poincare plot of the IBI series; and using the Poincare parameter(s) to determine a REM sleep of the sleeping subject. In some embodiments, sleep stages other than REM sleep and/or wake stages are determined.

Abstract: An ultrasonic imaging system comprises a processing system and an ultrasound imaging probe that is configured to transmit ultrasound energy into a selected portion of a subject and to receive echoes therefrom and to transmit data signals representative thereof to the processing system. The system further comprises a blood pressure sensor that is configured to measure the blood pressure of the subject and to transmit data signals representative thereof to the processing system. The processing system can processes the received ultrasound data signals to generate an ultrasound image and the received blood pressure data signals to generate a blood pressure trace. The processing system can also display the ultrasound image and blood pressure trace in a display image in which portions of the ultrasound image are displayed in temporal synchrony with portions of the blood pressure trace.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of at least a portion of an anatomical structure of the patient. The portion of the anatomical structure may include at least a portion of the patient's aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta. The at least one computer system may also be configured to create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific data, create a physics-based model relating to a blood flow characteristic within the portion of the anatomical structure, and determine a fractional flow reserve within the portion of the anatomical structure based on the three-dimensional model and the physics-based model.

Abstract: The present invention relates to determining or measuring a biological, physical or physiological parameter of an object (10) by a sensor (2). It may be beneficial to constantly monitor or determine a biological, physical or physiological parameter of an object (10) by a sensor (2), subsequently allowing for a preferred removal of the sensor (2) from object (10) when the monitoring is no longer required. Accordingly, a sensor (2) is provided, e.g. a flow sensor, employing a degradable adhesive (8) for attachment of the sensor (2) to the object (10). The degradable adhesive (8) may be degradable e.g. by time, by exposure to a certain measure, e.g. induced heat, or substance for detaching the sensor (2) from the object (10) for subsequent removal of the sensor (2).

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Provided is a device for measuring biomedical data from a testee, with a recording system for taking the data and a first hardware component for displaying the data. A device for electrical separation of the data is arranged in a connector line for transmitting the data from the recording system to the first hardware component for displaying the data. At least a duplication of the data for data processing purposes is thus guaranteed. The data processed in said manner are used for a method for real-time stimulation of a testee.

Abstract: A device for monitoring the heart of a patient including a housing, a computing device, an optical sensor adapted to provide signals to the computing device indicative of a distance from the optical sensor to a vessel carrying blood, as well a diameter of the vessel, a Doppler sensor adapted to provide signals to the computing device indicative of a velocity of the blood through the vessel, and an ECG sensor adapted to provide signals to the computing device indicative of a plurality of electrical stimuli that cause the heart to pump. The computing device uses signals from the optical sensor, the Doppler sensor, and the ECG sensor to compute parameters including oxygen saturation of the blood, blood flow, blood pressure, heart rate, and cardiac output.

Abstract: New algorithms to estimate cardiovascular indices by analysis of the arterial blood pressure (ABP) signal. The invention comprises recording and identification of cardiovascular descriptors (including ABP signal, diastolic pressure, systolic pressure, pulse pressure, and end systole), calculation of cardiovascular system parameters, and calculation of aortic blood flow, stroke volume, cardiac output, total peripheral resistance, and characteristic time constant.

Abstract: A personal authentication method comprising imaging, on an image sensor as a laser speckle using an optical system, light reflected from retinal blood vessels of the ocular fundus and a blood vessel layer in ocular fundus internal tissue when a laser beam is expanded and made to irradiate the ocular fundus, calculating a quantity that represents the rate of change with respect to time of the amount of light received for each pixel of the laser speckle, obtaining an ocular fundus blood flow map as a two-dimensional map of the numerical values of the quantity, and comparison-checking against pre-registered personal data utilizing at least one, observed in the blood flow map, of blood flow distribution data, a pattern reflecting the course of retinal blood vessels, a pattern reflecting the course of blood vessels in ocular fundus internal tissue observed superimposed thereon, and data on changes thereof over time, and a device therefor.

Abstract: The present invention provides a method for monitoring long-term potentiation and long-term depression, comprising placing a subject in head down bed rest position and monitoring in real-time cerebral mean blood flow velocity using a transcranial Doppler device during psychophysiologic tasks. The method involves using Fourier analysis of mean blood flow velocity data to derive spectral density peaks of cortical and subcortical processes. The effect of head-down bed rest at different time intervals is seen as accentuation of the cortical peaks in long-term potentiation and attenuation of subcortical peaks in long-term depression, relative to baseline. The effect of different interventions could be evaluated for research, diagnosis, rehabilitation and therapeutic use.

Abstract: A method and system for biometric identity confirmation is based on the pulse wave of a subject. During an initial enrollment mode, pulse wave data for a known subject are used to generate subject characterization data for the known subject. During a subsequent operational mode, pulse wave data for a test subject are analyzed using the subject characterization data to confirm whether the identity of the test subject matches the known subject. The subject characterization data can be a probability density in a phase space in which at least two quasi-periodic variables based on the pulse wave (e.g., blood pressure and volume time-series data) are correlated.

Abstract: A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography.

Abstract: A blood rheology measuring apparatus has a measuring portion for measuring a flow velocity of the blood flowing in a blood vessel of a person in a mode of a Doppler shift signal by transmitting and receiving a wave to and from a surface of the person's skin. An information processing portion calculates an intensity at each of frequency components of the Doppler shift signal, extracts a maximum frequency in a signal at an intensity level equal to or larger than a threshold in the histogram or a maximum frequency when an integrated value from a low frequency component reaches a predetermined rate of a total thereof in the histogram, and provides a temporal change waveform of the extracted frequency. The blood rheology is analyzed by an area value of a portion at and above a line connecting a minimum value of one pulse waveform and a minimum value of a successive pulse waveform of the frequency waveform.

Abstract: The present invention provides for an improved combination sensor tip that includes an ultrasound transducer and a pressure sensor both disposed at or in close proximity to the distal end of the combination sensor tip. The present invention also provides for an improved connector to couple a guide wire to a physiology monitor that reduces torsional resistance when maneuvering the guide wire.

Abstract: A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.

Abstract: An implanted system includes at least two optical sensors implanted proximate to an artery of a patient such that one optical sensor is upstream of another optical sensor. Arterial pulses of the patient may be detected based on electrical signals from at least one of the optical sensors. In addition, electrical signals from the optical sensors may be used to minimize the effects of motion artifacts on the detection of arterial pulses. For example, a detected pulse may be determined to be a spurious pulse if the optical sensors indicate the occurrence of the pulse within a predetermined range of time. As another example, a first optical sensor signal may be shifted in time relative to a second optical sensor signal, and the signals may be correlated. An arterial pulse may be detected at a time at which a peak or trough amplitude value of the correlated signal is observed.

Abstract: A method includes obtaining both first inflow and first perfusion metrics for non-healthy tissue of interest, obtaining both second inflow and second perfusion metrics for healthy tissue of interest, and concurrently presenting both the first flow and perfusion metrics for the non-healthy tissue of interest and both the second flow and perfusion metrics for the healthy tissue of interest.

Abstract: A hydrostatic finger cuff for blood flow property analysis is provided which includes an elongated substrate member having a pair of opposing long edges and a pair of opposing short edges. The hydrostatic finger cuff is configured to form a frustoconical shell when the ends of the cuff are overlapped and releasably connected together. The interior of the frustoconical shell conforms to the shape of the finger or thumb. One side of the elongated member has an inflatable member that has a pressurizable interior region. A tube is fixed to the inflatable member and is in pneumatic communication with the interior of the inflatable member inflatable to a maximum of no more than 60 mmHg. The inflatable member completely circumscribes the finger and provides substantially uniform contact across the entire length of a phalange.

Abstract: A catheter includes a flexible shaft having a length sufficient to access a patient's renal artery relative to a percutaneous access location. A treatment arrangement is provided at a distal end of the shaft and configured for deployment in the renal artery. The treatment arrangement includes an ablation arrangement configured to deliver renal denervation therapy. An occlusion arrangement is configured for deployment in the renal artery and for altering blood flow through the renal artery during or subsequent to renal denervation therapy delivery. A monitoring unit is configured for monitoring for a change in one or more physiologic parameters influenced by the renal denervation therapy. The monitoring unit is configured to produce data useful in assessing effectiveness of the renal denervation therapy based on the physiologic parameter monitoring.

Abstract: A surgical system and corresponding methods for identifying tissue or vessels and assessing their conditions includes a probing signal source for applying a probing signal to the tissue and a response signal monitor for monitoring a response signal that varies according to the level of blood circulation in the tissue or vessels. The response signal monitor monitors the response signal over an interval equal to or longer than an interval between two successive cardiac contractions. The surgical system includes a microprocessor that analyzes the amplitude and/or phase of the response signal to determine the level of blood circulation in the tissue or in different portions of the tissue, and determines a tissue parameter based upon the level of blood circulation. The surgical system may monitor a cardiac signal related to cardiac contractions and correlate the response signal and the cardiac signal to determine a level of blood circulation in the tissue.

Abstract: Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of embodiments, the invention consists of methods and devices for identifying patients whose Pulmonary Embolism or associated symptoms are caused or exacerbated, at least in part, by blockages of one or more of the patient's internal pulmonary veins. In some instances, stenoses or other flow limiting structures or lesions in the patient's affected veins are identified. Further, in some instances the nature of such lesions and whether there is a significant disruption of blood pressure, or both, is ascertained. In some embodiments, methods and devices for applying one or more therapies to the blockages in the patient's pulmonary veins are provided.

Abstract: A method and system for assessing blood volume within a subject includes generating a cardiovascular waveform representing physiological characteristics of a subject and determining blood volume of the subject by analyzing the cardiovascular waveform. The step of analyzing includes generating a first trace of the per heart-beat maximums of the cardiovascular waveform, which is representative of the systolic pressure upon the cardiovascular signal, generating a second trace of the per heart-beat minimums of the cardiovascular waveform, which is representative of the diastolic pressure upon the cardiovascular signal, and comparing the respective first trace and the second trace to generate an estimate of relative blood volume within the subject. In accordance with an alternate method of analyzing harmonic analysis is applied to the cardiovascular waveform, extracting a frequency signal created by ventilation and applying the extracted frequency signal in determining blood volume of the subject.

Abstract: Visible light is a treatment option for Segmental Vitiligo (SV), and visible light-induced repigmentation is associated normalization of sympathetic. Currently it is difficult to predict individual patient's response to visible light therapy. Therefore, the present invention uses the Laser Doppler Flowmeter to serve as a response predictor for visible light on treating SV. The present invention recruited 14 Segmental Vitiligo patients for evaluating clinical information. FirstLaser Doppler Flowmeter was used to evaluate the cutaneous blood flow of SV lesion and contralateral normal skin, and then treated them with visible light irradiate, cold-stress, rewarmed, and recorded the change of skin blood flow, finally the patients received regular visible light treatment for 3 months, and patients have a sign of repigmentation after the treatment.

Abstract: Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

Abstract: The present invention provides a package for an apparatus for non-invasively monitoring of blood flow of an object, a magnetic field sensing device, and a magnetic source positioning device.

Abstract: Devices, and methods for synchronizing cerebro-hemodynamic signals are disclosed. In one aspect, the devices and methods may include synchronizing first and second signals indicative of hemodynamic characteristics within a subject's brain. Differences may be determined between the synchronized signals and used to provide information for diagnosing changes in arterial occlusion. Differences between the synchronized signals may include differences, such as timing delays, between signature features of the synchronized signals. The first and second signals may be indicative of hemodynamic characteristics in first and second hemisphere's of a subject's brain. The first and second signals may be bioimpedance signals.

Abstract: The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine.

Abstract: The present invention provides for an improved combination sensor tip that includes a pressure sensor and a second sensor other than a pressure sensor, both disposed at or in close proximity to the distal end of the combination sensor tip. The present invention also provides for an improved connector to couple a guide wire to a physiology monitor that reduces torsional resistance when maneuvering the guide wire.

Abstract: PROBLEMS TO BE SOLVED: A finger arterial elasticity measuring program, a finger arterial elasticity measuring device and a finger arterial elasticity measuring method are provided for making it possible to measure an elasticity index of a finger artery in accordance with a pulse wave of a finger artery without measuring a blood pressure in evaluating the elasticity of the finger artery related to the degree of arterial sclerosis in an easy and least expensive manner.

Abstract: It is provided a blood vessel function inspecting apparatus including: a blood vessel diameter measuring portion configured to measure a diameter of a blood vessel; a blood vessel wall thickness measuring portion configured to measure a wall thickness of the blood vessel; and a blood vessel function index value calculating portion configured to calculate a function index value for diagnosing the blood vessel of its function, after releasing of the blood vessel from blood flow obstruction, by dividing an amount of dilatation of said diameter of the blood vessel continuously measured by said blood vessel diameter measuring portion, by the wall thickness measured by said blood vessel wall thickness measuring portion.