Abstract: The disclosure provides for a systems and methods for monitoring uterine contractions of a uterus of a mammal by reconstructing three-dimensional images of uterine surface electrical activity based on a noninvasively obtained body-uterus geometry and a plurality of body surface electrical potential maps.

Abstract: A vital signs monitoring system includes a peak pattern detection module configured to output a peak prediction signal from sensor signals based on a peak prediction algorithm; a vital sign estimating module configured to estimate a vital sign based on the peak prediction signal; an activity and context detector module configured to output a context signal based on at least one environmental condition and/or activity level of the person; and a concept drift detection module configured to output a drift signal based on drift detected in the estimated vital sign. The peak pattern prediction module is configured to update the peak prediction algorithm based on the context signal and the drift signal.

Abstract: The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. Analog versions of these signals pass through a low-profile cable to a wrist-worn transceiver that encloses a processing unit. Also within the wrist-worn transceiver is an accelerometer, a wireless system that sends information through a network to a remote receiver, e.g. a computer located in a central nursing station.

Abstract: In some examples, an apparatus configured to be worn by a patient for cardiac defibrillation comprises sensing electrodes configured to sense a cardiac signal of the patient, defibrillation electrodes, therapy delivery circuitry configured to deliver defibrillation therapy to the patient via the defibrillation electrodes, communication circuitry configured to receive data of at least one physiological signal of the patient from at least one sensing device separate from the apparatus, a memory configured to store the data, the cardiac signal, and a machine learning algorithm, and processing circuitry configured to apply the machine learning algorithm to the data and the cardiac signal to probabilistically-determine at least one state of the patient and determine whether to control delivery of the defibrillation therapy based on the at least one probabilistically-determined patient state.

Abstract: A blood treatment machine includes a patient comfort feedback mechanism configured to be adjusted by a patient to indicate comfort levels of the patient. The machine is configured to adjust one or more treatment parameters based on the patient feedback.

Abstract: Improvements in ingestible electronics with the capacity to sense physiologic and pathophysiologic states have transformed the standard of care for patients. Yet despite advances in device development, significant risks associated with solid, non-flexible gastrointestinal transiting systems remain. Here, we disclose an ingestible, flexible piezoelectric device that senses mechanical deformation within the gastric cavity. We demonstrate the capabilities of the sensor in both in vitro and ex vivo simulated gastric models, quantified its key behaviors in the GI tract by using computational modeling, and validated its functionality in awake and ambulating swine. Our piezoelectric devices can safely sense mechanical variations and harvest mechanical energy inside the gastrointestinal tract for diagnosing and treating motility disorders and for monitoring ingestion in bariatric applications.

Abstract: An apparatus and a method of measuring bioinformation are provided. The apparatus for measuring bioinformation includes a first sensor configured to measure a first biosignal including arterial pulse wave information, a second sensor configured to measure a second biosignal including venous or capillary pulse wave information, and a bioinformation estimator configured to estimate bioinformation of a user based on a time delay between the first biosignal and the second biosignal.

Abstract: In a microrunner structure, there are provided with components for a cleaning procedure required to conduct electrochemical sensing when a biosensor is activated for sensing; and a urine signal detection device that is a SoC (System on a Chip), which has a wireless transceiving circuit for receiving a urine measurement method and channel information transmitted from an intelligent device, and in turn, outputting a stimulus signal to trigger a biosensor or a non-biosensor in a multi-channel structure to conduct urine sense processing for a sensing area, as well as transmitting detection processing for a concentration of urine substances from the electrochemical sensing to the intelligent device through the wireless transceiving circuit to assess a risk index between a heart disease or diabetes and a kidney disease.

Abstract: A detection report data generation method including acquiring event type information of an electrocardiogram event corresponding to electrocardiogram event data, wherein the event data has one or more pieces of event type information; screening the event data according to signal quality evaluation indexes so as to obtain report conclusion data and report entry data; carrying out quality assessment on an event segment included in the event data according to the signal quality evaluation indexes, and determining a pre-selected sample segment according to a quality assessment result; determining position information of an event heart beat in the pre-selected sample segment, and determining segment interception parameters; carrying out interception processing on the pre-selected sample segment according to the segment interception parameters so as to obtain a typical data segment; generating report graphic data according to the typical data segment; and outputting the entry data, the graphic data and the conclusi

Abstract: Signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, detected events are analyzed to identify changes in detected event amplitudes. When detected event amplitudes are dissimilar from one another, a first set of detection parameters may be invoked, and, when detected event amplitudes are similar to one another, a second set of detection parameters may be invoked. Additional examples determine whether the calculated heart rate is “high” or “low,” and then may select a third set of detection parameters for use when the calculated heart rate is high.

Abstract: A device, system, and method to control activation of oxygen saturation (SpO2) measurements in a cardio-pulmonary resuscitation (CPR) procedure. When compressions are present, only a PPG-based pulse detection algorithm is performed. When a spontaneous pulse has been detected and compressions are not detected during a predetermined time period, both a PPG-based pulse detection algorithm and an SpO2 measurement algorithm are performed. Depending on whether a chest compression is delivered manually or automatically, parameter selections for the compression detection algorithm, the PPG-based pulse detection algorithm, and the SpO2 measurement algorithm are adjusted accordingly.

Abstract: Systems and methods for detecting atrial tachyarrhythmias (AT) such as atrial fibrillation (AF) are disclosed. A medical system can include a cardiac signal sensor circuit to sense a cardiac electrical signal and a heart sound (HS) sensor to sense heart a HS signal A cardiac electrical signal metric, including a cycle length variability or a detection of atrial electrical activity, can be generated from the cardiac electrical signal A HS metric can be generated from the HS signal, including a status of detection of S4 heart sound or a S4 heart sound intensity indicator. The system can include an AT detector circuit that can detect an AT event, such as an AF event, using the cardiac electrical signal metric and the HS metric. The system can additionally classify the detected AT event as an AF or an atrial flutter event.

Abstract: Limited-number-of-use neuromodulator apparatuses that may be comfortably worn on the skin of a user to non-invasively apply transdermal electrical stimulation (TES). The apparatuses described herein may be include a flexible/bendable substrate and an elastomeric cover (e.g., formed of an elastomeric fabric). These apparatuses may be simplified, to run autonomously. These apparatuses may also include improved power management features.

Abstract: An autonomous drug delivery system advantageously utilizes physiological monitor outputs so as to automatically give a bolus of a rescue drug or other necessary medication when certain criteria and confidence levels are met. An emergency button is provided to manually trigger administration of the rescue drug. The rescue drug may be an opioid antagonist in response to an analgesia overdose, a hypotensive drug to avert an excessive drop in blood pressure or an anti-arrhythmia drug to suppress abnormal heartbeats, to name a few.

Abstract: Systems and methods for reconstructing heart sounds from heart sound samples taken under a sub-optimal condition, such as at a low sampling rate, are discussed. An exemplary system receives acceleration information from a patient sensed at a first sampling rate, and generate a heart sound ensemble of portions of acceleration information over multiple cardiac cycles. The system can reconstruct a heart sound segment to have a second sampling rate, higher than the first sampling rate, using the generated heart sound ensemble. A heart sound metric can be generated using the reconstructed heart sound segment, and used for detecting a cardiac event, such as a cardiac arrhythmia episode, or a worsening heart failure event.

Abstract: Systems, methods, and computer program products are disclosed that may be used for photoplethysmogram data analysis and presentation. For example, photoplethysmogram (PPG) signal data is received as communicated by a PPG sensor of a wearable device worn by a user. A heartbeat interval may be determined from at least the PPG signal data. Also, an electrocardiogram (ECG)-type waveform spanning the heartbeat interval may be generated at a graphical interface.

Abstract: A medical device is configured to produce a cardiac motion signal by sampling a signal produced by an axis of a motion sensor, starting a blanking period, suspending the sampling of the signal during at least a portion of the blanking period, and restarting the sampling of the signal at the sampling frequency before the blanking period has expired. The medical device may detect a cardiac event from the cardiac motion signal and generate a pacing pulse in response to detecting the cardiac event in some examples.

Abstract: A system and method adapted for at least one health-related application selected from physiological monitoring, defibrillation, and pacing in the presence of electromagnetic interference (EMI) using the time-domain features of EMI patterns and physiological waveforms. The invention enables EMI detection and identification in a plurality of signals, including various physiological signals, which may contain both physiological information and EMI-generated artifacts. The system utilizes adaptive and versatile modular architecture with a set of modules for various filtering, conditioning, processing, and wireless transmission functions, which can be assembled in different configurations for different settings. In some preferred embodiments, the method and system of this invention are incorporated into (or attached to) an external cardiac defibrillator/monitor or cardiac pacing device.

Abstract: This document discusses, among other things, systems and methods for monitoring a patient at risk of epilepsy. A system comprises a sensor circuit that senses from the patient at least first and second physiological or functional signals. A wellness detector circuit can detect an epileptic event using the sensed physiological or functional signals, or additionally classify the epileptic event into one of epileptic seizure types. The system can generate a wellness indicator based on a trend of the physiological or functional signal during the detected epileptic event. The wellness indicator indicates an impact of the detected epileptic event on the health status of the patient. The system includes an output unit configured to output the detection of the epileptic event or the wellness indicator to a user or a process.

Abstract: A system includes a controller coupled to one or more sensors. The controller receives sensor data indicative of biometric data an occupant of a vehicle seat from the sensors. The controller receives the sensor data and analyzes the data to provide biometric data associated with the occupant of the vehicle seat.

Abstract: A method of monitoring sleep comprises simultaneously recording a person's electrocardiogram (ECG) and photoplethysmogram (PPG), deriving a plurality of parameters from the recorded data, and providing an output indicative of a sleep characteristic based upon an analysis of the parameters. The ECG and PPG may be recorded using an apparatus which is a combination of a Holter monitor and a pulse oximeter, which is wearable in ambulatory manner.

Abstract: A method is for the automated evaluation of at least one image data record of a patient recorded with a medical image recording device for the preparation of diagnostic findings. In the method, at least one item of input data describing the patient and/or the recording process and/or the examination target is determined after completion of the recording of the image data record. A selection algorithm which evaluates the image data record and the input data is used for determining at least one automated evaluation process to be applied and applicable and at least one image quality measure with regard to the evaluation process is determined by evaluating the image data record. The selected automated evaluation process is only performed for an image quality measure meeting a threshold quality requirement.

Abstract: A system includes an ambulatory medical device and a server.

Abstract: A method for analyzing heart rate variability, and an apparatus and use thereof, the method for analyzing heart rate variability including collecting ECG data in vitro; digitizing and denoising the ECG data; forming the processed ECG data into a sinus NN interval sequence; selecting sinus NN interval data of 4 hours in an awake state; performing MSE calculation on the sinus NN interval sequence of 4 hours in an awake state; and extracting parameters representing the complexity of a heart rate by using MSE curves. The present invention may provide accurate and efficient screening for drug-refractory epilepsy patients who are suitable for vagus nerve stimulation surgery, thus avoiding unnecessary expenses, and avoiding missing the most opportune moment for treatment. At the same time, patients suitable for VNS surgery are selected by using MSE complexity feature parameters of ECG, thus improving the overall efficacy of VNS therapy.

Abstract: A method of determining atrial fibrillation includes determining if a patient's pulse beats form an irregular pattern. If so, presence of an irregular pulse is indicated to a patient and, an electrocardiogram is obtained for determining atrial fibrillation. Initially, a pulse is detected at regular time intervals from a first appendage when motionless, using a pulse detector and pulse rhythms from a succession of time intervals, each corresponding to a respective interval of time between successive pulse beats of a sequence of the pulse beats. Then, a second appendage makes contact with an electrically conductive unit, and electrocardiogram signals are detected simultaneously with pulse rhythms while the first appendage is motionless and both appendages are relaxed. The signals are then analyzed to determine whether, in combination, they are indicative of atrial fibrillation.

Abstract: A device for detecting a pressure of a fluid medium is described. The device includes at least one housing having at least two pressure feeds; at least one sensor module, the sensor module being accommodated in the housing, the sensor module including at least one support element, the support element including at least one substrate and at least one molding compound, the support element further including at least one passage opening, the passage opening entirely penetrating the support element; at least one pressure sensor element for detecting the pressure, the pressure sensor element including at least one diaphragm, the pressure sensor element covering the passage opening; at least one control and evaluation unit, the control and evaluation unit being at least partially enclosed by the molding compound. A method for manufacturing the device is also described.

Abstract: The present disclosure describes a method and device to monitor the heart of a subject using radio signals. Availability of a portable heart monitor that can be used in a subject's home can increase patient compliance and improve diagnosis rates of cardiac conditions. A mobile heart monitor can be especially useful to those subjects who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital.

Abstract: An incident management system with graphical user interface mechanisms for control of the routing of incoming calls and other information regarding a plurality of ongoing incidents. Thumbnail icons, each corresponding to a different defined geographic area, are displayed and, in response to a user input selecting a thumbnail icon, a map is displayed identifying a defined geographic area corresponding to the selected thumbnail icon with a plurality of call icons and at least one incident icon. The call icons each correspond to a different active incoming call from within the defined geographic area and are each positioned on the map accordingly. At least one of the displayed call icons is assigned to an incident group and an incident icon is displayed for each ongoing incident managed by the system to which at least one displayed call icon has been assigned.

Abstract: The present invention relates to a method for configuring a management unit connected to at least one home automation equipment (17) comprising at least one home automation device (D) and at least one central control unit (U), the method being implemented by a management unit (Sv) and comprising the following steps: configuring (EcfSv2) an alert (AI) corresponding to the triggering of a notification (N) and/or an action (Ac) when a triggering condition (Cnd, Cndp) is produced relating to at least one state variable (S) for a home automation device (D), a group of home automation devices (D), a type of home automation device (DT) or a group of types of home automation devices (DT); the step of configuring an alert (AI) being carried out on the basis of instructions of a first user (Usr1) having a first user profile type (UsrT1); declaring (ECfUsr25) the monitoring of an assembly (SDS) of home automation devices (D) comprising at least one home automation device (D) for which at least one alert (AI) has been de

Abstract: This disclosure describes systems and methods for a graphical interface including a graphical representation of medical data. The graphical interface platform may receive medical data and provide medical safety reporting capabilities including reporting of history data and real-time visual monitoring data. The graphical interface platform may be configured to identify potential problems and corrections to medical devices in operation while a reporting cycle is underway through visual representation of performance metrics.

Abstract: A medical ventilator (100, 200) including a first user interface (114) having a touch-sensitive display having a display area; and at least one controller (104) which determines whether a second user interface (122, 222) having a touch-sensitive display is coupled to the medical ventilator, enables the first user interface when it is determined that the second user interface is not coupled to the medical ventilator, and enables the second user interface when it is determined that the second user interface is coupled to the medical ventilator.

Abstract: The disclosure is directed towards posture-responsive therapy. To avoid interruptions in effective therapy, an implantable medical device may include a posture state module that detects the posture state of the patient and automatically adjusts therapy parameter values according to the detected posture state. A system may include a memory that stores posture state definitions, a posture state module that records a plurality of postures of a patient over a period of time, and a processor that identifies a set of the plurality of postures that fall within a posture state, and redefines a boundary of the posture state based on where the postures fall within the posture state.

Abstract: Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.

Abstract: There is provided a method of creating a presentation of a current awake-energy level, comprising: computing an estimate of initial awake-energy at a wake-up time of a target individual according to sleep-parameters computed according to a time interval that includes a previous night sleep, computing an estimate of a current awake-energy of the target individual indicative of a remaining amount of an estimated maximal amount of available awake-energy, computed according to the initial awake-energy and according to awake-parameters computed for an awake-time interval based on output of sensor(s) comprising: a physiological sensor that senses a physiological parameter, and/or an activity sensor that senses an activity, and outputting, via a user interface, an indication of the current awake-energy, wherein the computing the current awake-energy and the outputting are dynamically iterated over the awake-time interval while the target individual is awake.

Abstract: The technology herein relates to a troubleshooting system for remote patient monitoring. A plurality of triggering conditions defines a data transmission error between a sensor and a remote location. A data transmission log is configured to receive characterization data defining each successful data transmission between a communicator and the remote location. An input user interface is configured to receive input from a user and an output user interface is configured to provide notification to a user. Processing circuitry is in communication with the input interface and the output interface, where the processing circuitry is configured to compare each of the triggering conditions to the characterization data to identify a data transmission error. Upon identification of the data transmission error, the processing circuitry causes the output interface to present a query to the user.

Abstract: A method includes applying electrical stimulation therapy via an electrode relative to an upper-airway-patency-related nerve to treat obstructive sleep apnea. A level of the electrical stimulation therapy is assessed.

Abstract: An apparatus and a method of monitoring fat burning in a subject non-invasively by measuring electric conductivity or resistance on the skin.

Abstract: An ECG sensor chip used in a wearable appliance includes; a switch controlled —by a switching signal, an amplifier that amplifies a difference between first and second ECG signals, and a location indicator that generates the switching signal. The switch passes either a first ECG signal or second ECG signal in response to the switching signal.

Abstract: An exemplary method includes determining a variability of a plurality of measurements of a cardiovascular parameter of a patient suffering from hypertension, the plurality of measurements recorded one at a time over a predetermined time period. The method further includes comparing the determined variability with a predetermined reference value. If the comparing indicates that the determined variability is less than the predetermined reference value, the method includes designating the patient to be within a first class of patients representative of patients that are likely to be responsive to subcutaneous neuromodulation therapy as a treatment for hypertension. If the comparing indicates that the determined variability is greater than the predetermined reference value, the method includes designating the patient to be within a second class of patients representative of patients that are likely to be unresponsive to subcutaneous neuromodulation therapy as a treatment for hypertension.

Abstract: A system and method are provided for diagnosis of animal respiratory diseases using auscultation techniques. Animal lung sounds are recorded and stored as digitized data. Algorithms are applied to the data producing an output indicative of the health of the animal. Another method determines effectiveness of antibiotics administered to animals based upon observed relationships between lung score categories obtained from auscultation. A comparison is made between sample populations of animals that receive different classifications of antibiotics, and this data is compared to lung score categories observed for each of the animals that received the antibiotics. A statistical analysis is conducted to confirm statistical differences in case fatality rates between lung score categories.

Abstract: The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another.

Abstract: A method of monitoring and/or diagnosing an autoregulation mechanism of blood pressure of a living being using an ECG signal includes recording the ECG signal of the living being, and the recording a pulse wave curve synchronously with the recording of the ECG signal. Heart rate intervals are determined from the ECG signal. A pulse wave transit time is determined for each heart rate interval from the pulse wave curve. A plurality of significant changes in the pulse wave transit times are determined according to a specified criterion. One respective heart rate interval correlated in time with each significant change in the pulse wave transit times is selected as an anchor point. A determined limited number of temporally successive heart rate intervals temporally before and/or after each anchor point are selected to thus generate a limited sequence of heart rate intervals for each anchor point.

Abstract: The invention provides a signal synchronization device, which obtains electrocardiographic, heart sound signal calibration factors by performing time domain and frequency domain transformations for an electrocardiographic signal and a heart sound signal, and thereby performs calibration for the electrocardiographic signal and the heart sound signal to synchronize the electrocardiographic signal and the heart sound signal in time domain, such that a diagnosis rate for cardiovascular disease is increased. Moreover, the invention further provides a stethoscope with signal synchronization processing, an auscultation information output system and a symptom diagnosis system capable of signal synchronization.

Abstract: The present disclosure pertains to a system (10) configured to determine spectral boundaries (216, 218) for sleep stage classification in a subject (12). The spectral boundaries may be customized and used for sleep stage classification in an individual subject. Spectral boundaries determined by the system that are customized for the subject may facilitate sleep stage classification with higher accuracy relative to classifications made based on static, fixed spectral boundaries that are not unique to the subject. In some implementations, the system comprises one or more of a sensor (16), a processor (20), electronic storage (22), a user interface (24), and/or other components.

Abstract: A wearable patch system includes an electrocardiogram (ECG) sensor having electrodes configured to contact a subject. An electronic stethoscope has a diaphragm structure responsive to sounds from the subject. The ECG sensor and the electronic stethoscope are co-located to measure respective parameters concurrently from a same position. A housing is configured to support the diaphragm structure and the electrodes. The housing includes a mechanical interface configured to mount on the subject. A communications circuit is disposed on or in the housing to communicate with a remote component.

Abstract: A method of automatically determining which type of treatment is most appropriate for a cardiac arrest victim, the method comprising transforming one or more time domain electrocardiogram (ECG) signals into a frequency domain representation comprising a plurality of discrete frequency bands, combining the discrete frequency bands into a plurality of analysis bands, wherein there are fewer analysis bands than discrete frequency bands, determining the content of the analysis bands, and determining the type of treatment based on the content of the analysis bands.

Abstract: Physiological monitoring can be provided through a wearable monitor that includes two components, a flexible extended wear electrode patch and a removable reusable monitor recorder. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline (or immediately to either side of the sternum) benefits extended wear by removing the requirement that ECG electrodes be continually placed in the same spots on the skin throughout the monitoring period. The wearable monitor can interoperate wirelessly with other physiology and activity sensors and mobile devices, and can include cellular phone capabilities. The power usage of the wireless communication can be reduced by using a low energy wireless transceiver in the monitor. The monitor detects that the monitor has been adhered to the patient and begin collecting physiological data after such detection, preserving battery power.

Abstract: A bio-information acquiring terminal for acquiring bio-information includes a bath device. The bath device is provided with a bio-information measuring unit configured to measure bio-information of a user taking a bath, and a fingerprint authentication unit configured to specify the user. According to the above configuration, it is possible to easily manage daily changes of the health condition of the user in his or her daily life.

Abstract: A system to generate medical monitor alarm settings (10) which includes a normative analyzer (36) and/or observational analyzer (48) configured to receive (130) data from logs (32, 34) of a plurality of medical monitors (12), and generate (134, 138) one or more suggested alarm settings (26) based on a constructed model of the received log data.

Abstract: In one aspect, the present disclosure relates to a method including obtaining, by a fitness tracking device, a plurality of heart rate measurements of the user over a period of time, wherein the plurality of heart rate measurements can include heart rate data from a heart rate sensor of the fitness tracking device; analyzing, by the fitness tracking device, the plurality of heart rate measurements to determine a rate of change of a heart rate of the user during the period of time; determining, by the fitness tracking device, that the user is experiencing an onset phase if the rate of change of the heart rate during the period of time is greater than zero; determining, by the fitness tracking device, that the user is experiencing a cool-down phase if the rate of change of the heart rate during the period of time is less than zero; estimating, by the fitness tracking device, a first rate of energy expenditure of the user if the user is experiencing an onset phase using an onset calorimetry model; and estimating