Heart Patents (Class 600/508)
  • Patent number: 11116989
    Abstract: A computer implemented method for determining heart arrhythmias based on cardiac activity that includes under control of one or more processors of an implantable medical device (IMD) configured with specific executable instructions to obtain far field cardiac activity (CA) signals at electrodes located remote from the heart, and obtain acceleration signatures, at an accelerometer of the IMD, indicative of heart sounds generated during the cardiac beats. The IMD is also configured with specific executable instructions to declare a candidate arrhythmia based on a characteristic of at least one R-R interval from the cardiac beats, and evaluate the acceleration signatures for ventricular events (VEs) to re-assess a presence or absence of at least one R-wave from the cardiac beats and based thereon confirming or denying the candidate arrhythmia.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: September 14, 2021
    Assignee: PACESETTER, INC.
    Inventors: Jong Gill, Gene A. Bornzin
  • Patent number: 11102306
    Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: August 24, 2021
    Assignee: DexCom, Inc.
    Inventors: Michael Robert Mensinger, John Michael Dobbles, Apurv Ullas Kamath, Beat Stadelmann, Deborah M. Ruppert, Nasser Salamati, Richard C. Yang
  • Patent number: 11096619
    Abstract: A neural analysis and treatment system includes a computing device with a memory for storing an application that is executable on a processor to receive amplitude-integrated electroencephalography (aEEG) and range-EEG (rEEG) measurements associated with a patient. The systems determine a spectral edge frequency (SEF) measurement from the received EEG measurements, and determine one or more neural characteristics of the patient according to the determined SEF, aEEG, and rEEG measurements. These neural characteristics may then be used to identify and implement an appropriate therapeutic treatment.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: August 24, 2021
    Assignee: Innara Health, Inc.
    Inventors: Steven M. Barlow, David L. Stalling, Kenneth Aron
  • Patent number: 11090022
    Abstract: The invention discloses a quality testing method dynamic test phantom simulating cardiovascular motion for quality evaluation of CT imaging, and its control principle and quality testing method.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: August 17, 2021
    Assignee: THE SECOND AFFILIATED HOSPITAL OF PLA ARMY MEDICAL UNIVERSITY
    Inventors: Peng Zhao, YinBao Chong, WenCai Pan, Lang Lang, Jiaqing Yang, Jingjing Xiao, Jieshi Ma, ShiHui Zhang
  • Patent number: 11083388
    Abstract: A near-field sensor method and device for obtaining cardiovascular information is disclosed. A transmission-line aperture arrangement configured to guide electromagnetic waves and emit near-field fringing energy, is placed near the skin. The transmission line is excited at a narrow-band Gigahertz frequency. The near-field fringing energy emitted by the sensor device penetrates at least partially into the skin and underlying blood vessels, and this energy is partially absorbed and partially phase shifted in a time varying manner according to the changes in physiology of the skin. The status of the sensor device is monitored over a plurality of time intervals, and changes in both the phase and the amplitude of the signals passing though the transmission line are used to determine the cardiovascular information such as heart rates. Various transmission-line configurations, and various reference transmission-line methods to reduce low-frequency noise, are also discussed.
    Type: Grant
    Filed: November 6, 2016
    Date of Patent: August 10, 2021
    Inventors: Jun-Chau Chien, Stanley Yuanshih Chen
  • Patent number: 11064918
    Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 20, 2021
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna
  • Patent number: 11051751
    Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment, including either suspending or adjusting turn schedule based on various types of patient movement. The sensor can include bi-axial or tri-axial accelerometers, as well as resistive, inductive, capacitive, magnetic and other sensing devices, depending on whether the sensor is located on the patient or the support surface, and for what purpose.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: July 6, 2021
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Barrett J Larson, Daniel Z. Shen, Mark V. Weckwerth, Charles Matthew Peterson Hammond
  • Patent number: 11039796
    Abstract: Embodiments are directed to methods and systems for adaptive heart rate monitoring. In one scenario, a method for adaptive heart rate monitoring includes receiving, from a pulse-oximeter, a sensor signal, where the sensor signal is photoplethysmogram waveform. The method next includes generating a frequency-domain photoplethysmogram waveform by applying a transform algorithm to the sensor signal, and dividing the resulting frequency-domain photoplethysmogram waveform into discrete frequency regions. The method further includes identifying a fundamental heart rate harmonic within one of the discrete frequency regions by analyzing each discrete frequency region according to a specified analytic algorithm, and triggering a user interface to display a biometric measurement corresponding to the identification of the fundamental heart rate harmonic.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: June 22, 2021
    Assignee: Owlet Baby Care, Inc.
    Inventor: Sean Kerman
  • Patent number: 11026638
    Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: June 8, 2021
    Assignee: KARDIUM INC.
    Inventors: Saar Moisa, Michael Hermann Weber
  • Patent number: 11026637
    Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: June 8, 2021
    Assignee: KARDIUM INC.
    Inventors: Saar Moisa, Michael Hermann Weber
  • Patent number: 10990179
    Abstract: A haptic presentation apparatus that includes a force sensor that detects force input to an operation portion that is operated by a user, and generates an electric signal corresponding to the detected force, a vibration actuator that presents tactile sensation to the user, a vibration damping member to be interposed between the force sensor and the vibration actuator; a first mechanical part contacting the force sensor; and a second mechanical part contacting the vibration actuator, and the vibration damping member is provided between the first mechanical part and the second mechanical part, such that the vibration damping member contact neither the force sensor nor the vibration actuator.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: April 27, 2021
    Assignee: SONY CORPORATION
    Inventors: Hiroyuki Suzuki, Ryuta Horie, Kenichiro Nagasaka
  • Patent number: 10987044
    Abstract: The present invention includes devices, systems and methods in the field of uroflowmetry, more specifically in the field of home uroflowmetry. In one aspect, the present invention discloses a core unit comprising an accelerometer; a urine detector; a weight sensor; a communication module; a microprocessor; and, an energy source. Further provided is a uroflowmetry device comprising said core unit.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: April 27, 2021
    Assignee: MINZE NV
    Inventors: Josef Sageder, Jiri Vermeulen
  • Patent number: 10987012
    Abstract: A system for managing care of a person receiving emergency cardiac assistance includes one or more capacitors arranged to deliver a defibrillating shock to a person; one or more electronic ports for receiving a plurality of signals from sensors for obtaining indications of an electrocardiogram (ECG) for the person; and a patient treatment module executable on one or more computer processors using code stored in non-transitory media and to provide a determination of a likelihood of success from delivering a future defibrillating shock to the person with the one or more capacitors, using a mathematical computation applied to a vector value defined by signals from at least two of the plurality of signals.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: April 27, 2021
    Assignee: ZOLL Medical Corporation
    Inventors: Weilun Quan, Gary A. Freeman
  • Patent number: 10973455
    Abstract: A method and an apparatus for analyzing heart rate Variability (HRV), and use thereof are provided. A low-cost, portable and wearable signal acquisition device is utilized to acquire electrocardiography (ECG) signals of epilepsy patients for 24 hours before treatment, and a time domain index, a frequency domain index and a nonlinear index of the ECG during a long term and during a short term are calculated with a programmed HRV analysis method, and the efficacy of vagus nerve stimulation (VNS) treatment for patients with medically intractable epilepsy is accurately and efficiently predicted based on characteristic parameters for characterizing an effect level of the vagus nerve regulating the heart rate, i.e., vagus nerve activity, thereby avoiding unnecessary costs and avoiding the delay of the optimal treatment timing. In addition, the characteristic parameters obtained by the HRV analysis on the ECG may be utilized to clearly select VNS treatment indication patients.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: April 13, 2021
    Assignees: BEIJING PINS MEDICAL CO., LTD, TSINGHUA UNIVERSITY
    Inventors: Luming Li, Hongyun Liu, Zhao Yang
  • Patent number: 10977789
    Abstract: A surgical instrument navigation system is provided that visually simulates a virtual volumetric scene of a body cavity of a patient from a point of view of a surgical instrument residing in the cavity of the patient, wherein the surgical instrument, as provided, may be a steerable surgical catheter with a biopsy device and/or a surgical catheter with a side-exiting medical instrument, among others. Additionally, systems, methods and devices are provided for forming a respiratory-gated point cloud of a patient's respiratory system and for placing a localization element in an organ of a patient.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: April 13, 2021
    Assignee: Veran Medical Technologies, Inc.
    Inventors: Troy L. Holsing, Mark Hunter
  • Patent number: 10959618
    Abstract: The present invention is directed to a method for combining assessment of different factors of dyssynchrony into a comprehensive, non-invasive toolbox for treating patients with a CRT therapy device. The toolbox provides high spatial resolution, enabling assessment of regional function, as well as enabling derivation of global metrics to improve patient response and selection for CRT therapy. The method allows for quantitative assessment and estimation of mechanical contraction patterns, tissue viability, and venous anatomy from CT scans combined with electrical activation patterns from Body Surface Potential Mapping (BSPM). This multi-modal method is therefore capable of integrating electrical, mechanical, and structural information about cardiac structure and function in order to guide lead placement of CRT therapy devices. The method generates regional electro-mechanical properties overlaid with cardiac venous distribution and scar tissue.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: March 30, 2021
    Assignee: The Johns Hopkins University
    Inventors: Fady Dawoud, Karl H. Schuleri, Amir Pourmorteza, Albert C. Lardo, Elliot McVeigh
  • Patent number: 10925684
    Abstract: Devices and methods for assessing tissue contact based on dielectric properties and/or impedance sensing are disclosed. In some embodiments, one or more probing frequencies are delivered via electrodes including an electrode in proximity to a tissue (for example, myocardial tissue). In some embodiments, dielectric parameter values, optionally together with other known and/or estimated tissue characteristics, are measured to determine a contact quality with the tissue. In some embodiments, dielectric contact quality is used, for example, in guiding the formation of a lesion (for example, RF ablation of heart tissue to alter electrical transmission characteristics).
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: February 23, 2021
    Assignee: Navix International Limited
    Inventors: Yitzhack Schwartz, Eli Dichterman, Adi Rabinovich
  • Patent number: 10918341
    Abstract: A physiological parameter system has one or more parameter inputs responsive to one or more physiological sensors. The physiological parameter system may also have quality indicators relating to confidence in the parameter inputs. A processor is adapted to combine the parameter inputs, quality indicators and predetermined limits for the parameters inputs and quality indicators so as to generate alarm outputs or control outputs or both.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: February 16, 2021
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, John Graybeal, Massi Joe E. Kiani, Michael Petterson, Chris Kilpatrick
  • Patent number: 10918302
    Abstract: There is provided a biological signal processing apparatus. The biological signal processing apparatus includes a biological signal extraction unit (2) configured to extract a biological signal from an electrocardiographic waveform measured by an electrocardiograph (1), an averaging processing unit (3) configured to calculate averaged data using time-series data of the biological signals extracted by the biological signal extraction unit (2), an abnormal value determination unit (4) configured to determine, for each data, whether the data of the biological signal extracted by the biological signal extraction unit (2) is appropriate, based on the averaged data calculated using the data of the biological signals that have occurred before the data, and an abnormal value processing unit (5) configured to perform one of deletion and interpolation of the data of the biological signal determined to be inappropriate by the abnormal value determination unit (4).
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: February 16, 2021
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Nobuaki Matsuura, Takayuki Ogasawara, Kei Kuwabara
  • Patent number: 10912491
    Abstract: A system for monitoring a person may include a person-worn sensor device including at least one sensor (e.g., at least one accelerometer, magnetometer, altimeter, etc.) configured to collect sensor data and a processor to process data from the person-worn sensor device. The processor may be configured to determine or access an orientation of a physical support apparatus (e.g., bed, table, wheelchair, chair, sofa, or other structure for supporting the person), receive sensor data collected by the person-worn sensor device, calculate an orientation of the person relative to the physical support apparatus based on (a) the orientation of the physical support apparatus and (b) the sensor data collected by the person-worn sensor device, and identify, based on the determined orientation of the person relative to the physical support apparatus, a physical support apparatus exit condition indicating an occurrence or anticipated occurrence of the person exiting the physical support apparatus.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: February 9, 2021
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Daniel Shen, Barrett Larson, Mark Weckwerth
  • Patent number: 10912508
    Abstract: A computer-implemented method of assessing a mental state of a subject (106) includes receiving (302), as input, a heartbeat record (200) of the subject. The heartbeat record comprises a sequence of heartbeat data samples obtained over a time span which includes a pre-sleep period (208), a sleep period (209) having a sleep onset time (224) and a sleep conclusion time (226), and a post-sleep period (210). At least the sleep onset time and the sleep conclusion time are identified (304) within the heartbeat record. A knowledge base (124) is then accessed (306), which comprises data obtained via expert evaluation of a training set of subjects and which embodies a computational model of a relationship between mental state and heart rate characteristics. Using information in the knowledge base, the computational model is applied (308) to compute at least one metric associated with the mental state of the subject, and to generate an indication of mental state based upon the metric.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: February 9, 2021
    Assignee: MEDIBIO LIMITED
    Inventors: Matthew Flax, Aaron Wong, Michael Player, Todd Jolly, Hans Stampfer
  • Patent number: 10898160
    Abstract: The present invention relates to a system (100) and method (800) capable of indirectly monitoring respiratory and cardiac variables. A decomposition technique on time-series of features extracted from the chest audio signal ?(t) is proposed. The proposed monitoring system (100) may acquire the acoustic signal on the chest of a subject (140) by means of a wearable transducer (150). The proposed system may estimate a number of physiological variables such as flow estimates, respiration rate, inspiration and expiration markers and cardiac related variables. Cough and apnea detection, adventitious sound recognition, activities performed, and information about energy estimation and the status of a monitored subject can be derived as well.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: January 26, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Gabriele Spina, Albertus Cornelis Den Brinker
  • Patent number: 10898093
    Abstract: Apparatus for assessing scarring of cardiac tissue, consisting of a probe and a processor. The probe has one or more electrodes, which are configured to contact the tissue at a plurality of positions and to sense respective voltages in the tissue at the positions. The processor receives the respective voltages, and computes a triangular mesh that is representative of a surface of the tissue and that consists of multiple triangles having vertices corresponding to the positions contacted by the one or more electrodes. The processor calculates respective scar areas within the triangles by comparing the respective voltages sensed at the positions corresponding to the vertices to a predefined range of the voltages that is associated with scarring, and computes a sum of the respective areas. The processor compares the sum to a total area of the triangles so as to assess a degree of the scarring of the tissue.
    Type: Grant
    Filed: December 25, 2018
    Date of Patent: January 26, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Michael Timofeyev, Tal Haim Bar-on, Gal Hayam, Inbal Dubiner
  • Patent number: 10888251
    Abstract: A method is provided for automatically determining the status of a wearable sensor device configured to be worn by a user. The wearable sensor device includes at least one accelerometer that generates device acceleration data indicating an acceleration of the sensor device. The device acceleration data is used for both (a) a sensor device attachment analysis and (b) a turn protocol compliance analysis. The sensor device attachment analysis includes comparing the device acceleration data to stored reference data, determining an attachment or position status of the sensor device with respect to the user based on the comparison, and generating a corresponding alert notification. The turn protocol compliance analysis includes monitoring an orientation of the user based on the device acceleration data, comparing the monitored user orientation to at least one turn parameter defined by a turn protocol, and generating a turn protocol alert notification based on the comparison.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: January 12, 2021
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Barrett J. Larson, Daniel Z. Shen
  • Patent number: 10885463
    Abstract: Training prediction models and applying machine learning prediction to data is illustrated herein. A prediction instance comprising a set of data and metadata associated with the set of data identifying a prediction type is obtained. The data and metadata are used to determine an entity to train a prediction model using the prediction type. A trained prediction model is obtained from the entity. A notification system may be configured to react to monitor contextual information and apply the prediction. A workflow system may automatically perform a function in a workflow based on prediction.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: January 5, 2021
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Klaus Marius Hansen, Andreea-Bogdana Botez, Andrei S. Panko, Thomas Hejlsberg, Marko Perisic
  • Patent number: 10874330
    Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: December 29, 2020
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Barrett J. Larson, Daniel Z. Shen
  • Patent number: 10874321
    Abstract: A phase singularity identification system includes: a signal reception unit for receiving a single activity electrogram signal measured through a single-electrode catheter at a particular point of a cardiac muscle cell; a phase calculation unit for calculating a phase from the received single activity electrogram signal; and a phase singularity identification unit for identifying through the calculated phase if the particular point of the cardiac muscle cell is a phase singularity. Accordingly, it is possible to identify the phase singularity of a rotor by using a single-electrode catheter rather than a multi-electrode catheter, thereby significantly reducing time required and costs spent in comparison with prior art, and it is possible to accurately identify the phase singularity of the rotor, thus the system can be used for a radiofrequency electrode catheter ablation procedure for cardiac arrhythmia treatment.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: December 29, 2020
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY
    Inventors: Hui Nam Pak, Jun Seop Song
  • Patent number: 10856752
    Abstract: The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 8, 2020
    Assignee: SOTERA WIRELESS, INC.
    Inventors: Matt Banet, Isaac Henry, Donald Bernstein
  • Patent number: 10856806
    Abstract: A system and method for monitoring lung water content of a patient. The system may include at least two microwave sensors and a processor. The system may transmit one or more microwave signals into the thorax of a patient using one or more of the microwave sensors. The system may then receive one or more of the microwave signals using one or more of the microwave sensors. The one or more received microwave signals may each have at least one associated frequency component with a magnitude and a phase. The system may analyze the phase of one or more received microwave signals to monitor changes in the lung water content. The system may analyze the magnitude of one or more received microwave signals to determine whether the lung water content is increasing or decreasing.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: December 8, 2020
    Inventors: Magdy F. Iskander, Ruthsenne R. G. Perron
  • Patent number: 10856938
    Abstract: Systems are provided for assessing the likelihood that a sample of cardiac tissue will spontaneously exhibit disordered electrical activity. These systems induce ventricular tachycardia or other disordered electrical activity in a sample of human and/or animal cardiac tissue either in vivo or in vitro. This system can be used to assess the ability of various pharmaceuticals, genetic modifications, electrical pacing, surgical ablation, or other therapeutic interventions to prevent or halt such disordered electrical activity. This system detects electrical activity from a plurality of points on the surface of the sample of cardiac tissue and generates one or more maps of monophasic action potential amplitude, monophasic action potential duration, local field amplitude, or other electrophysiological parameters of the cardiac tissue.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: December 8, 2020
    Assignee: THE ARIZONA BOARD OF REGENTS ON BEHAFT OF THE UNIVERSITY OF ARIZONA
    Inventors: Ikeotunye Royal Chinyere, Jen Watson Koevary, Jordan Lancaster, Steven Goldman, Russell Witte, Kyle Weigand
  • Patent number: 10842392
    Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: November 24, 2020
    Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SA
    Inventors: Erik Tang, Matthew Banet, Marshal Dhillon, James McCanna, Mark Dhillon
  • Patent number: 10832595
    Abstract: Disclosed is a medico-surgical simulator and to a corresponding method. The medico-surgical simulator includes a vascularization device and/or a ventilation device, as well as a regulation device. The medico-surgical simulator is arranged so as to be connected to a cadaver and to vascularize an arterial system of the cadaver via the vascularization device and/or to ventilate a respiratory system of the cadaver via the ventilation device. The regulation device controls the vascularization and ventilation devices in such a way as to simulate cardiorespiratory functions for providing surgical training carried out on the cadaver with a very high degree of realism.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: November 10, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERS, CENTRE HOSPITALIER UNIVERSITAIRE DE POITIERS, INSERM—INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Jean-Pierre Richer, Jean-Pierre Faure, Denis Oriot, Cyril Breque, Pierre Olivier Delpech, Daniel-Aïham Ghazali
  • Patent number: 10806394
    Abstract: In an information processing method, a computer acquires a sleep state of a person existing in space, acquires detection data output from a sensor that detects entry of an object into the space, performs a first determination to determine whether or not the sleep state changes to awakening within a predetermined time from a time point at which the object is estimated to enter the space based on the sleep state and the detection data, generates, in association with the sleep state before the time point, awakening information for determining possibility that the person is awakened by entry of the object in a case where the person is in the sleep state before the time point of entry based on a result of the first determination, and presents the awakening information associated with the sleep state via a presentation device.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: October 20, 2020
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Akihiro Michimori, Hiroko Sugimoto
  • Patent number: 10806192
    Abstract: A wetsuit is provided which comprises (a) a first central region comprising a first material and having a first thickness; and (b) a second lateral region comprising a second material and having a second thickness. The buoyancy per unit area of the first region is greater than the buoyancy per unit area of the second region.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: October 20, 2020
    Assignee: ROKA SPORTS, INC
    Inventors: Robert Allen Canales, Kurt Robert Spenser
  • Patent number: 10799148
    Abstract: A method of detecting a localization element/sheath state change with a localization system includes establishing a localization field using a plurality of localization field generators, obtaining first and second localization signals from first and second catheter-borne localization elements within the localization field, respectively, comparing the quadrature components of the first and second localization signals, and detecting a localization element/sheath state change for one of the catheter-borne localization elements based on the comparison between quadrature components. For example, withdrawal of a localization element into an introducer sheath can be detected when the comparison between quadrature components exceeds a preset amount. Conversely, re-emergence of the localization element from the introducer sheath can be detected when the comparison between quadrature components returns below the preset amount.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: October 13, 2020
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Artem Mosesov, Anthony D. Hill, Birin Yucesan, Timothy G. Curran
  • Patent number: 10796714
    Abstract: The present invention extends to methods, systems, for diagnosing coronary artery disease (CAD) in patients by using their voice signal comprising receiving voice signal data indicative of speech from the patient.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 6, 2020
    Assignee: VOCALIS HEALTH LTD.
    Inventors: Yoram Levanon, Yotam Luz
  • Patent number: 10765329
    Abstract: Provided is a system and method of generating an aggregated stability map of one or more rotational sources associated with a heart rhythm disorder. In accordance therewith, a plurality of rotational area profile maps is accessed for a plurality of analysis intervals. Each of the rotational area profile maps includes rotation intensity values for a plurality of locations associated with rotation of the one or more rotational sources. Thereafter, an aggregated stability map is generated map based on the plurality of rotational area profile maps, wherein the aggregated stability map includes a plurality of locations. Each location includes a rotation intensity value based at least on a filter level of highest rotation intensity values for that location from corresponding locations of the plurality of rotational area profile maps.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: September 8, 2020
    Assignee: Topera, Inc.
    Inventors: William Robert Macneil, Carey Robert Briggs, Christopher Todd Schuster, Heather A. Drury
  • Patent number: 10765873
    Abstract: A system for supplementing communications capabilities of a patient monitoring device, the system including an interface device configured to communicably couple with and to receive the patient monitoring information from the patient monitoring device, a memory device hosted by the interface device and configured to store at least a portion of the patient monitoring information, a wireless transceiver hosted by the interface device, a database hosted by the interface device; and a processor communicably coupled to the wireless transceiver and the asset management database, the processor configured to format the patient monitoring information into one or more data objects, each of the one or more data objects associated with an EMS incident during which the patient monitoring information was gathered, the processor further configured to store the one or more data objects to the database and to transmit the one or more data objects with the wireless transceiver.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: September 8, 2020
    Assignee: ZOLL Medical Corporation
    Inventors: Michael Scott Martin, Chad Ashmore, Eric A. Deines, Gary A. Freeman, Joseph L. Helmick, Thomas E. Kaib, Richard A. Rattanni, C. Shane Reid, Jeremy Ryan Soller, Shane S. Volpe, Gary Ruggiero, Frederick J. Geheb
  • Patent number: 10758162
    Abstract: A system for monitoring a person may include a person-worn sensor device including at least one sensor (e.g., at least one accelerometer, magnetometer, altimeter, etc.) configured to collect sensor data and a processor to process data from the person-worn sensor device. The processor may be configured to determine or access an orientation of a physical support apparatus (e.g., bed, table, wheelchair, chair, sofa, or other structure for supporting the person), receive sensor data collected by the person-worn sensor device, calculate an orientation of the person relative to the physical support apparatus based on (a) the orientation of the physical support apparatus and (b) the sensor data collected by the person-worn sensor device, and identify, based on the determined orientation of the person relative to the physical support apparatus, a physical support apparatus exit condition indicating an occurrence or anticipated occurrence of the person exiting the physical support apparatus.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: September 1, 2020
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Daniel Shen, Barrett Larson, Mark Weckwerth
  • Patent number: 10758191
    Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: September 1, 2020
    Assignee: KARDIUM INC.
    Inventors: Saar Moisa, Michael Hermann Weber
  • Patent number: 10751006
    Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: August 25, 2020
    Assignee: KARDIUM INC.
    Inventors: Saar Moisa, Michael Hermann Weber
  • Patent number: 10751003
    Abstract: Vital sign monitors are plagued by noisy photoplethysmography (PPG) data, making it difficult for the monitors to output consistently accurate readings. Noise in PPG signals is often caused by motion. The present disclosure provides improved techniques for reducing motion-related artifacts in optical/PPG measurements for vital signs monitoring. In general, techniques described herein are based on using measurements of reference sensors that include sensors other than optical sensors used for the optical measurements, e.g., biopotential sensors, bioimpedance sensors, and/or capacitive sensors. In particular, techniques described herein aim to filter PPG signals using substantially only the noise components of signals generated by reference sensors, by attenuating or altogether eliminating components of the signals generated by reference sensors which are indicative of the parameter the reference sensors are designed to measure.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: August 25, 2020
    Assignee: ANALOG DEVICES GLOBAL UNLIMITED COMPANY
    Inventors: Roberto Munoz, Guillermo Serrano Leon, Carlos Millan Navarro
  • Patent number: 10746852
    Abstract: A method for monitoring periodic motions of one or more subjects uses signal reflections from the subjects. The method includes emitting a transmitted signal from a transmitting antenna and receiving a received signal at one or more receiving antennas. The received signal includes a combination of a number of reflections of the transmitted signal, at least some of which are associated with the subjects. The received signal, including the reflections, is processed to determine an estimate of a fundamental frequency of the periodic motions.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: August 18, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Fadel Adib, Zachary Edward Kabelac, Dina Katabi
  • Patent number: 10740634
    Abstract: A computer-implemented method is disclosed. The method includes preparing a base of an anomaly detection model for generating a score that indicates an estimation of a concentration decline. The anomaly detection model has parameters affecting the score. The method also includes preparing a set of training data, each of which includes a sequence of sensor data relating to activity performed by an individual. The method also includes optimizing the parameters of the anomaly detection model using the set of the training data so as to make a score for longer cumulative activity high as compared to shorter cumulative activity. The method further includes outputting the parameters of the anomaly detection model, in which the anomaly detection model having the parameters is used for detecting a concentration decline of a target individual.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: August 11, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Takayuki Katsuki, Kun Zhao, Takayuki Yoshizumi
  • Patent number: 10741290
    Abstract: Measurement of circulating ST2 and natriuretic peptide (e.g., NT-proBNP) concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, transplantation, and heart failure.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: August 11, 2020
    Assignee: Critical Care Diagnostics, Inc.
    Inventors: James V. Snider, Robert W. Gerwien, Sven Jacobson
  • Patent number: 10729357
    Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: August 4, 2020
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Barrett J. Larson, Daniel Z. Shen
  • Patent number: 10722130
    Abstract: The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: July 28, 2020
    Assignee: SOTERA WIRELESS, INC.
    Inventors: Matt Banet, Isaac Henry, Donald Bernstein
  • Patent number: 10722184
    Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: July 28, 2020
    Assignee: KARDIUM INC.
    Inventors: Saar Moisa, Michael Hermann Weber
  • Patent number: 10694970
    Abstract: A signal process system and the method for the same and a biological resistance detection device and element used to perform corresponding signal process for sensory signal sensed by a sensor, wherein a minor AC electrical signal is injected into a biological tissue to be measured in order to sense the sensory signal of the biological tissue to be measured by means of the principle of Ohm's Law. Moreover, the sensory signal may be processed to restore a biological property of the measured biological tissue and to create an equivalent circuit parameter model representative of the biological property.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: June 30, 2020
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Shuenn-Yuh Lee, Tsung-Han Tsai
  • Patent number: 10688304
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP may include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine an atrial contraction timing fiducial based at least in part upon two or more of a signal from the pressure sensor, a signal from the accelerometer representing, and an electrical cardiac signal.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: June 23, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Yinghong Yu, Michael J. Kane, Jeffrey E. Stahmann, Keith R. Maile