Variation In Duration Of Segment Of Pqrst Signal Waveform (e.g., Qrs Complex, Etc.) Detected Patents (Class 600/516)
  • Patent number: 11331497
    Abstract: An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine a representative signal based on the cardiac signal, the representative signal having a single polarity, and determine an end of a T-wave of the cardiac signal based on an area under the representative signal.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: May 17, 2022
    Assignees: Medtronic, Inc., UMC Utrecht Holding B.V.
    Inventors: Alfonso Aranda Hernandez, Berthold Stegemann, Marc A. Vos, David J. Sprenkeler
  • Patent number: 11324435
    Abstract: A heartbeat detection device including a time difference value calculation unit to calculate a time difference value from a sampling data string of an electrocardiographic waveform of a living body, an index value calculation unit to calculate an index value for heartbeat detection based on the time difference value, a threshold setting unit to determine whether a peak of the index value exceeding a threshold can be detected, to calculate, a threshold candidate based on an average value of the predetermined number of the most recent peaks among these peaks. A threshold candidate is set as a new threshold when the threshold candidate has a value equal to or less than a threshold limit value. A heartbeat time determination unit sets the sampling time of the peak as the heartbeat time when the peak of the index value exceeding the threshold is detected.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: May 10, 2022
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Nobuaki Matsuura, Kei Kuwabara, Takayuki Ogasawara, Ryoichi Kasahara, Koji Fujii
  • Patent number: 11312143
    Abstract: In one example in accordance with the present disclosure, a fluid interface device (106) is described. The device includes a collar (110) to receive a fluid container (104). The collar has an aperture in one end surface. A needle (108) of the fluid interface device passes through the aperture and allows fluid to pass from the fluid container (104) into a reservoir (102). The needle is slideable within the aperture from a dosed position to an open position upon reception of the fluid container. A seal (212) is radially disposed around the needle (108) and seals against the end surface of the collar (110) when the needle is in the dosed position.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: April 26, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Anthony D. Studer, Robert S. Wickwire
  • Patent number: 11284830
    Abstract: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: March 29, 2022
    Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.
    Inventors: Qing Lou, Meredith E. Stone, Qingguo Zeng, Jeffrey B. Adair, Connor S. Edel, Ping Jia, Kevin R. Ponziani, Brian P. George, Ryan M. Bokan, Matthew J. Sabo, Vladimir A. Turovskiy, Ketal C. Patel, Charulatha Ramanathan
  • Patent number: 11229396
    Abstract: A method for automatically discriminating between a supraventricular tachycardia event and a ventricular tachycardia event is provided.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 25, 2022
    Assignee: Medtronic, Inc.
    Inventor: Ewald Himmrich
  • Patent number: 11123012
    Abstract: A system and method of measuring bioelectric signals generated by an individual, inclusive of humans or other living organisms, comprises a plurality of sensors, at least one of the plurality of sensors being constituted by a capacitive-type sensor. Sensor has an associated insulated layer of material preventing the conduction of direct current between an electrode and individual, wherein a bioelectric signal of individual can be measured underwater.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: September 21, 2021
    Assignee: Quantum Applied Science & Research, Inc.
    Inventors: Igor V. Fridman, Robert Matthews
  • Patent number: 11064949
    Abstract: A method and an apparatus to remove a noise from an electrocardiography (ECG) sensor signal are provided. A noise removing method includes: receiving a sensor signal collected by an electrocardiography (ECG) sensor; extracting an ECG estimation signal from the sensor signal based on a peak value of the sensor signal; determining a first comparison value between the ECG estimation signal and a first reference signal indicating an average form of ECG signals; and classifying the ECG estimation signal as one of an ECG signal and a noise by comparing the first comparison value to a first threshold value.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: July 20, 2021
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Chisung Bae, Jinhyun Yun, Sang Joon Kim
  • Patent number: 10981001
    Abstract: A method of pacing a His bundle of a patient heart using a stimulation system including a memory, a pulse generator, a stimulating electrode and at least one sensing electrode includes applying a plurality of impulses through the stimulating electrode to induce a plurality of responses from the patient heart. Each impulse of the plurality of impulses is delivered at a different impulse energy corresponding to a respective output setting of the stimulation system. The response characteristics for each of the plurality of responses are measured and each impulse is assigned a classification based on whether the respective response characteristics indicate capture of one or both of the His bundle and a ventricle of the patient heart. The output setting and classification for each impulse is then stored in the memory.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: April 20, 2021
    Assignee: PACESETTER, INC.
    Inventors: Julie Prillinger, Gene A. Bornzin, Stuart Rosenberg, Aditya Goil, Wenwen Li, Pritika Toutam, Didier Theret, Fujian Qu
  • Patent number: 10974058
    Abstract: Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: April 13, 2021
    Assignee: CAMERON HEALTH, INC.
    Inventors: Venugopal Allavatam, Surekha Palreddy, Rick Sanghera, Jay A. Warren
  • Patent number: 10912479
    Abstract: A method for accurately extracting an abnormal potential within a QRS, comprising: in an ideal electrocardiographic signal pre-estimation stage, pre-estimating an ideal electrocardiographic signal using a non-linear transformation technology; according to the pre-estimated ideal electrocardiographic signal, further estimating the ideal electrocardiographic signal by using a spline method, so as to accurately estimate the ideal electrocardiographic signal; and according to the accurately estimated ideal electrocardiographic signal, accurately extracting an abnormal potential within the QRS by means of a mobile standard deviation analysis technology. The method can be used not only on an average electrocardiographic signal after multiple superimposition, but also on a single beat electrocardiographic signal.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: February 9, 2021
    Inventors: Xiangguo Yan, Ning Wu, Chongxun Zheng, Gang Wang
  • Patent number: 10874322
    Abstract: A computer implemented method and system are provided for detecting premature ventricular contractions (PVCs) in cardiac activity. The method and system obtain cardiac activity (CA) signals for a series of beats, and, for at least a portion of the series of beats, calculate QRS scores for corresponding QRS complex segments from the CA signals. The method and system calculate a variability metric for QRS scores across the series of beats, calculate a QRS complex template using QRS segments from the series of beats, calculate correlation coefficients between the QRS complex template and the QRS complex segments, compare the variability metric to a variability threshold and the correlation coefficients to a correlation threshold, and designate the CA signals to include a predetermined level of PVC burden based on the comparing.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: December 29, 2020
    Assignee: PACESETTER, INC.
    Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
  • Patent number: 10772575
    Abstract: An automatic measurement point correction method includes acquiring vital signs information waveform data indicating a vital signs information waveform having a plurality of waveforms which periodically appear on a time axis, determining a plurality of measurement points for measuring a predetermined measurement item of each waveform included in the vital signs information waveform, causing the vital signs information waveform and measurement point displayers to be displayed on a displaying section, correcting a first measurement point for measuring the predetermined measurement item of a first waveform of the plurality of waveforms, as a first correction, recording the corrected first measurement point as a reference measurement point, extracting a waveform which is analogous to the first waveform, from the plurality of waveforms, and automatically correcting a measurement point for measuring the predetermined measurement item of the extracted waveform, as a second correction.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: September 15, 2020
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Jiro Suto, Tsuneo Takayanagi, Takashi Kaiami
  • Patent number: 10772525
    Abstract: An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine a representative signal based on the cardiac signal, the representative signal having a single polarity, and determine an end of a T-wave of the cardiac signal based on an area under the representative signal.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: September 15, 2020
    Assignees: Medtronic, Inc., UMC UTRECHT HOLDING B.V.
    Inventors: Alfonso Aranda Hernandez, Berthold Stegemann, Marc A. Vos, David J. Sprenkeler
  • Patent number: 10687765
    Abstract: A system comprises a display and a processor. The processor is configured to display on the display in a graphical user interface (GUI), while a plurality of electrogram signals are acquired from a heart, a plurality of widgets corresponding to different respective electroanatomical maps generated from the electrogram signals, each of the electroanatomical maps being associated with a respective set of suitability criteria such that any one of the electrogram signals is used to generate the map only if the signal satisfies the set of suitability criteria. The processor is further configured to display in the GUI, in response to a user selecting any one of the widgets, a status of a most recently acquired one of the electrogram signals with respect to at least one criterion in the set of suitability criteria associated with the electroanatomical map to which the selected widget corresponds. Other embodiments are also described.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: June 23, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Yoav Benaroya, Lidia Tonkonogi Tarasenko, Hanna Cohen-Sacomsky, Lilia Suzdalnitsky, Morris Ziv-Ari, Dan Sztejnberg
  • Patent number: 10595813
    Abstract: A medical device system and associated method discriminate respiratory and cardiac conditions using respiratory sounds. A sensing module acquires a first signal and a second signal, at least the second signal acquired from an acoustic transducer. A processor is configured to receive the first signal and to control the sensing module to acquire the second acoustic signal in response to a change in the first signal. The processor discriminates between a cardiac condition and a respiratory condition as a cause of the change in the first signal in response to the second acoustic signal.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: March 24, 2020
    Assignee: Medtronic, Inc.
    Inventors: Zhendong Song, Xiaohong Zhou
  • Patent number: 10575749
    Abstract: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: March 3, 2020
    Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.
    Inventors: Qing Lou, Meredith E. Stone, Qingguo Zeng, Jeffrey B. Adair, Connor S. Edel, Ping Jia, Kevin R. Ponziani, Brian P. George, Ryan M. Bokan, Matthew J. Sabo, Vladimir A. Turovskiy, Ketal C. Patel, Charulatha Ramanathan
  • Patent number: 10555702
    Abstract: Described here are methods, devices and systems for characterizing a physiological signal such as an electrocardiogram (ECG) signal. Generally, the method includes receiving the ECG signal generated by an ECG device coupled to a patient. ECG signal quality for a plurality of consecutive beats may be determined based on a dispersion coefficient and a deviation from an average of each of a plurality of ECG parameters. Indexing information may be generated for set of sequences from the plurality of consecutive cardiac beats. Each of the sequences may comprise a first predetermined number of consecutive cardiac beats. The set of the sequences may be ordered based upon the ECG signal quality.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: February 11, 2020
    Assignee: eResearchTechnology, Inc.
    Inventors: Jean-Philippe Y. Couderc, Thuan G. Pham, Alexander Zapesochny
  • Patent number: 10398326
    Abstract: An example system and method associated with identifying and treating a source of a heart rhythm disorder are disclosed. In accordance with therewith, a spatial element associated with a region of the heart is selected. Progressive rotational activations or progressive focal activations are determined in relation to the selected spatial element. A plurality of indexes of progressive rotational activations or progressive focal activations over time is formed. One or more indexes are selected from the plurality of indexes that indicate consistency of the successive rotational activations or the progressive focal activations in relation to a portion of the region of the heart.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: September 3, 2019
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRE, TOPERA, INC.
    Inventors: Sanjiv Narayan, Carey Robert Briggs, Ruchir Sehra
  • Patent number: 10369360
    Abstract: The invention relates generally to systems and devices for material delivery, energy delivery, and/or monitoring electrophysiological activity, and method of use thereof. In particular, the present invention provides devices and systems, and methods of use thereof, configured to deliver therapeutic compositions, to provide electroporation and/or sonoporation to increase therapeutic efficiency, and to monitor electrophysiological activity, for example, before and after treatment.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: August 6, 2019
    Assignee: Northwestern University
    Inventors: Rishi Arora, Alan Kadish, Jason Ng
  • Patent number: 10362986
    Abstract: A sleep monitoring system includes an ECG device and a respiration inductance plethysmogram which monitor cardiac activity and physical respiration respectively and feed representative signals to a digital data processor. Operations process the beat interval data, while in a second thread, operations independently process the amplitude modulation of the ECG data caused by the respiratory motion of the subject. The inductance plethysmogram device provides an input to the processor which represents respiration as directly monitored independently of the ECG. Operations process this direct respiration data independently and in parallel, in a third thread. All extracted features are fed to a classifier which in step combines selected combinations of features to make decisions in real time.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: July 30, 2019
    Assignee: University College Dublin, National University Of Ireland
    Inventors: Conor Heneghan, Stephen Redmond
  • Patent number: 10328274
    Abstract: A cardiac medical system, such as an implantable cardioverter defibrillator (ICD) system, receives a cardiac electrical signal by and senses cardiac events when the signal crosses an R-wave sensing threshold. The system determines at least one sensed event parameter from the cardiac electrical signal for consecutive cardiac events sensed by the sensing circuit and compares the sensed event parameters to P-wave oversensing criteria. The system detects P-wave oversensing in response to the sensed event parameters meeting the P-wave oversensing criteria; and adjusts at least one of an R-wave sensing control parameter or a therapy delivery control parameter in response to detecting the P-wave oversensing.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: June 25, 2019
    Assignee: Medtronic, Inc.
    Inventors: Xusheng Zhang, Paul J. Degroot
  • Patent number: 10220219
    Abstract: Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: March 5, 2019
    Assignee: Cameron Health, Inc.
    Inventors: Venugopal Allavatam, Surekha Palreddy, Rick Sanghera, Jay A. Warren
  • Patent number: 10022060
    Abstract: A method and system for high-throughput prediction of the onset of heart arrhythmias observes trends in abnormal or pathologic morphology of the electrocardiogram (ECG). A first set of ECG signals is monitored from a patient. A baseline measurement is generated from the monitored first set of ECG signals to contain nonpathologic ECG morphologies in each lead. A second set of ECG signals is monitored from the patient and a second baseline measurement is generated from the second set of ECG signals. A residuum signal is generated for each lead based on the baseline measurement and the second baseline measurement. The residuum signals are averaged across the leads. R-wave heterogeneity, T-wave heterogeneity, P-wave heterogeneity, or ST-segment heterogeneity or other indicators of arrhythmia risk or myocardial ischemia are quantified based on the generated residuum signals and the averaged residuum signal.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: July 17, 2018
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Bruce D. Nearing, Richard L. Verrier
  • Patent number: 9986951
    Abstract: A method and system for low-distortion denoising of an ECG signal are disclosed. The method comprises determining at least one beat of the ECG signal for denoising using a beat selection logic and denoising the at least one beat using at least one ensemble averaging filter. The system includes a sensor to detect the ECG signal, a processor coupled to the sensor, wherein the processor includes a beat selection logic unit, and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to determine at least one beat of the ECG signal for denoising using a beat selection logic and to denoise the at least one beat using at least one ensemble averaging filter.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: June 5, 2018
    Assignee: Vital Connect, Inc.
    Inventors: Nima Ferdosi, Ravi Narasimhan
  • Patent number: 9848784
    Abstract: The invention relates to a method for determining the physical and/or psychological state of a subject. The heart rate variability (HRV) of the subject is analyzed in the time domain, wherein at least one frequency distribution of interbeat intervals (IBI) which are detected in at least one examination time period (1) is examined in the analysis. In order to obtain particularly significant and quickly interpretable information for this purpose, the frequency distribution is examined for a multimodal distribution.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: December 26, 2017
    Assignee: Tracer Systems GmbH
    Inventor: Nikolaus Klepp
  • Patent number: 9774589
    Abstract: A management method for outpatient electrocardiography on a patient using an ECG recorder, an administration network, a first mobile device and at least one second mobile device is provided. In order to initialize outpatient electrocardiography on a patient, the first mobile device is connected to the ECG recorder and to the administration network and in the process an identification code assigned to the ECG recorder is transmitted from the ECG recorder to the administration network. After the verification of the authorizations of the mobile device, at least one certificate assigned to the ECG recorder is provided by the administration network and is transmitted to the ECG recorder for storage via the mobile device. The second mobile device is connected to the ECG recorder and to the administration network and in the process the identification code assigned to the ECG recorder is transmitted from the ECG recorder to the administration network.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: September 26, 2017
    Assignee: GETEMED MEDIZIN—UND INFORMATIONSTECHNIK AG
    Inventors: Tilo Borchardt, Winfried Scharner, Michael Scherf, Robert Downes
  • Patent number: 9697175
    Abstract: An approach is provided for transforming curvature values into bin values for comprehensible description. The approach involves causing, at least in part, an application of at least one transformation function to one or more data values to transform the one or more data values into one or more bin values. The approach also involves causing, at least in part, a binning of the one or more bin values into one or more respective bins based, at least in part, on the one or more continuous bin values. The approach further involves processing and/or facilitating a processing of the one or more bin values in the respective one or more bins to determine statistical information for the respective one or more bins. The approach also involves causing, at least in part, a re-transformation of the statistical information, the one or more bin values, or a combination thereof into the one or more data values following the determination of the statistical information.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: July 4, 2017
    Assignee: HERE Global B.V.
    Inventor: James D. Lynch
  • Patent number: 9623255
    Abstract: Various aspects of the present subject matter provide an implantable medical device. In various embodiments, the device comprises a pulse generator, a first monitor and a controller. The pulse generator is adapted to generate a neural stimulation signal for a neural stimulation therapy. The neural stimulation signal has at least one adjustable parameter. The first monitor is adapted to detect an undesired effect. In some embodiments, the undesired effect is myocardial infarction. The controller is adapted to respond to the first monitor and automatically adjust the at least one adjustable parameter of the neural stimulation signal to avoid the undesired effect of the neural stimulation therapy. Other aspects are provided herein.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: April 18, 2017
    Assignee: Cardiac Pacemakers, Inc.
    Inventor: Imad Libbus
  • Patent number: 9585592
    Abstract: An information processing apparatus includes a retaining unit, an image acquisition unit, an image processor, a comparator, and an image generator. The retaining unit is configured to retain a defined attachment position being an attachment position of a biological detection sensor with respect to a body site of a user, the defined attachment position being defined in advance. The image acquisition unit is configured to acquire a capture image captured by an imaging unit. The image processor is configured to extract, from the capture image, a body shape of the user. The comparator is configured to compare the body shape with the defined attachment position. The image generator is configured to generate, based on a comparison result by the comparator, a display image to be displayed on a display unit.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: March 7, 2017
    Assignee: SONY CORPORATION
    Inventor: Haruhiko Soma
  • Patent number: 9579038
    Abstract: An electrode assembly for an EIT scanning device (11) including an electrode (15), a current supply unit (17), a voltage buffer unit (19), a switch logic unit (21), and lines for connecting the different elements, whereby the switch logic unit (21) comprises at least one element of a first shift register (27) and at least one element of a second shift register (29). A belt-like device comprising a plurality of said electrode assemblies. A method of measuring an EIT-image using such electrode assemblies preferably arranged in such a belt-like device.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: February 28, 2017
    Assignee: SWISSTOM AG
    Inventors: Josef X. Brunner, Nicolas Robitaille, Pascal Olivier Gaggero
  • Patent number: 9579064
    Abstract: Medical devices and methods for making and using medical devices are disclosed. A method for removing an artifact of a biological reference signal present in a biological source signal may comprise sensing a biological reference signal with one or more electrodes and sensing a biological source signal, wherein the biological source signal comprises an artifact of the biological reference signal. The method may further comprise determining, based on the biological reference signal, the artifact of the biological reference signal and subtracting the artifact of the biological reference signal from the sensed biological source signal.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: February 28, 2017
    Assignee: Boston Scientific Scimed Inc.
    Inventors: Vladimir V. Kovtun, Carlos Alberto Ricci, Pramodsingh Hirasingh Thakur, Shibaji Shome
  • Patent number: 9538919
    Abstract: A system and method are provided for the detection of a heart-related condition by obtaining information in real-time when a condition is initially identified as potentially occurring. A physical exercise and recovery episode is initially detected from physiological signals sensed in a patient. Once detected, a HR-ST segment deviation hysteresis analysis is performed in an implantable medical device (IMD) from certain physiological signals over portions of the exercise and recovery episode to identify the probability that a certain condition is occurring. Once a desired level of probability that the heart-related condition has been detected exists, data utilized in the analysis can be transmitted remotely for clinical review and confirmation of the device's detection of the condition. The patient may be prompted to answer questions related to symptoms that patient is experiencing through an input device in order further confirm the probability that the condition is occurring in the patient.
    Type: Grant
    Filed: July 9, 2008
    Date of Patent: January 10, 2017
    Assignee: Medtronic, Inc.
    Inventors: Willem Boute, David Robert Hampton, Wilbert Wesselink, Anna Pietersma
  • Patent number: 9480844
    Abstract: A method and apparatus for detecting a cardiac event in a medical device that includes sensing a cardiac signal, detecting a cardiac event in response to the sensed signal, determining whether an interval associated with the cardiac signal is less than an interval threshold, determining a noise metric in response to an interval associated with the cardiac signal being less than the interval threshold, determining whether the noise metric is greater than a noise metric threshold, and determining whether to inhibit detecting in response to determining whether an interval associated with the cardiac signal is less than the interval threshold and determining whether the noise metric is greater than the noise metric threshold.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: November 1, 2016
    Assignee: Medtronic, Inc.
    Inventors: Robert W. Stadler, Richard P. M. Houben, Tim Dirk Jan Jongen
  • Patent number: 9468766
    Abstract: An intracardiac pacemaker is configured to receive a cardiac electrical signal developed across a pair of electrodes coupled to the pacemaker and detect a crossing of a first sensing threshold of the cardiac electrical signal. A pacing escape interval timer is set to a first pacing escape interval in response to the cardiac electrical signal crossing the first sensing threshold. The pacing escape interval timer is adjusted if the cardiac electrical signal crosses a second sensing threshold during a time limit.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: October 18, 2016
    Assignee: Medtronic, Inc.
    Inventors: Todd J Sheldon, Wade M Demmer, Margaret G Guo
  • Patent number: 9451898
    Abstract: This invention discloses a system and a method for extracting VF signal in ECG recorded during uninterrupted CPR. The present invention provides a method for extracting a Ventricular fibrillation (VF) signal in Electrocardiography (ECG), comprising: receiving an ECG signal; adding a plurality of shadowing functions to the ECG signal, to obtain a plurality of modification signals; decomposing the plurality of modification signals by using an Empirical Mode Decomposition (EMD) method, to generate a plurality of Intrinsic Mode Functions (IMFs); calculating the sum of IMFs in different frequency regions based on time sequence, dividing by a number of the shadowing signal, to obtain a plurality of modification intrinsic mode functions; combining the plurality of modification IMFs with the same property, to obtain a shape function; modeling the shape functions to obtain a compression signal; and subtracting the compression signal from the ECG signal based on time sequence, to obtain the VF signal.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: September 27, 2016
    Assignee: NATIONAL CENTRAL UNIVERSITY
    Inventors: Men-Tzung Lo, Yung-Hung Wang, Chen Lin, Hsu-Wen Vincent Young, Hsiang-Chih Chang, Lian-Yu Lin, Wan-Hsin Hsieh, Matthew Huei-Ming Ma, Kun Hu
  • Patent number: 9427157
    Abstract: Technology for transmitting and receiving a biosignal based on a pattern related to the biosignal and a feature point included in the biosignal. A biosignal transmitter includes a biosignal obtaining unit configured to obtain a biosignal comprising a plurality of unit signals, a parsing unit configured to parse the biosignal to extract a first unit signal of the plurality of unit signals, a pattern obtaining unit configured to obtain a pattern related to the biosignal based on the first unit signal, and a transmitting unit configured to transmit information related to a feature point of the first unit signal based on the first unit signal and the pattern.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: August 30, 2016
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jae Min Kang, Kun Kook Park
  • Patent number: 9420957
    Abstract: A method of producing an artificial neural network capable of predicting the survivability of a patient, including: storing in an electronic database patient health data comprising a plurality of sets of data, each set having at least one of a first parameter relating to heart rate variability data and a second parameter relating to vital sign data, each set further having a third parameter relating to patient survivability; providing a network of nodes interconnected to form an artificial neural network, the nodes comprising a plurality of artificial neurons, each artificial neuron having at least one input with an associated weight; and training the artificial neural network using the patient health data such that the associated weight of the at least one input of each artificial neuron is adjusted in response to respective first, second and third parameters of different sets of data from the patient health data.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: August 23, 2016
    Assignees: SINGAPORE HEALTH SERVICES PTE LTD., NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Marcus Eng Hock Ong, Zhiping Lin, Wee Ser, Guangbin Huang
  • Patent number: 9375573
    Abstract: The present invention provides a system for providing neurological disease state information to a patient. The system comprises one or more sensors that sense at least one signal that comprise feature(s) that are indicative of a neurological disease state. A signal processing assembly is in communication with the one or more sensors and processes the at least one signal to estimate the neurological disease state. A patient interface module is in communication with the signal processing assembly and communicates with a patient an output that is indicative of the patient's estimated neurological disease state.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: June 28, 2016
    Assignee: CYBERONICS, INC.
    Inventor: Daniel John Dilorenzo
  • Patent number: 9361225
    Abstract: A system for writing data includes a memory, at least one memory controller and control logic. The memory stores data units. The memory controller receives a write request associated with a data unit and stores the data unit in the memory. The memory controller also transmits a reply that includes an address where the data unit is stored. The control logic receives the reply and determines whether the address in the reply differs from an address included in replies associated with other memory controllers by a threshold amount. When this occurs, the control logic performs a corrective action to bring an address associated with the memory controller back within a defined range.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: June 7, 2016
    Assignee: Juniper Networks, Inc.
    Inventors: Rami Rahim, Pradeep S. Sindhu, Raymond Marcelino Manese Lim, Sreeram Veeragandham, David Skinner
  • Patent number: 9314177
    Abstract: The present application discloses a method of detecting abnormal movement of a physical object. A periodic signal is representative of the movement of the object. According to some embodiments, a raw matrix having a first array and a second array is generated, and then an integrated matrix is generated by performing a dimension reduction on the raw matrix. A likelihood of a predetermined type of abnormal movement of the physical object is determined by comparing the integrated matrix with a predetermined benchmark pattern. In some embodiments, the generation of the raw matrix includes performing a first analysis on a predetermined portion of the periodic signal to generate the first array and performing a second analysis different from the first analysis on the predetermined portion of the periodic signal to generate the second array.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: April 19, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chuan-Wei Ting, Ching-Yao Wang
  • Patent number: 9254094
    Abstract: An implantable device for analyzing a high frequency (HF) electrogram signal including an implantable electrode, a signal pickup configured to pick up an electrogram signal including a HF component, a signal filter connected to the signal pickup and configured to measure a HF component from the signal only during a specific portion of a cardiac cycle, and an analyzer for analyzing the HF component, wherein the signal pickup, the signal filter and the analyzer are included within an implantable container, and the analyzer is configured to analyze at least one time-varying parameter of the HF component, and the signal filter is configured to measure the signal by using a signal picked up from at least one electrode selected from a group consisting of (a) intracardiac, (b) subcutaneous, (c) a can of the implanted device, (d) a combination of two of the above. Related apparatus and methods are also described.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: February 9, 2016
    Assignee: BSP Biological Signal Processing Ltd.
    Inventors: Tamir Ben-David, Yair Granot, Amir Beker
  • Patent number: 9254095
    Abstract: Apparatuses and methods for extracting, de-noising, and analyzing electrocardiogram signals. Any of the apparatuses described herein may be implemented as a (or as part of a) computerized system. For example, described herein are apparatuses and methods of using them or performing the methods, for extracting and/or de-noising ECG signals from a starting signal. Also described herein are apparatuses and methods for analyzing an ECG signal, for example, to generate one or more indicators or markers of cardiac fitness, including in particular indicators of atrial fibrillation. Described herein are apparatuses and method for determining if a patient is experiencing a cardiac event, such as an arrhythmia.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 9, 2016
    Assignee: ALIVECOR
    Inventors: Conner Daniel Cross Galloway, David E. Albert
  • Patent number: 9241667
    Abstract: System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: January 26, 2016
    Assignees: The Regents of the University of California, Topera, Inc., The United States of America as Represented by the Department of Veterans Affairs, Office of General Counsel
    Inventors: Sanjiv Narayan, Ruchir Sehra
  • Patent number: 9126045
    Abstract: A neurostimulation system measures a cardiac parameter at various cardiac intervals and analyzes its restitution, including computing a restitution slope being a rate of change of the restitution parameter with respect to change in the cardiac interval. In various embodiments, the system uses the restitution slope to provide for adaptive control of neurostimulation. In various embodiments, one or more cardiac parameters such as action potential duration (APD), conduction velocity (CV), QT interval (QT), and/or T-wave morphology (TM) parameter are measured and analyzed for restitution of each parameter, which is then used to control the delivery of the neurostimulation.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: September 8, 2015
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Shibaji Shome, Stephen Ruble, Jason J. Hamann, Stephen J. Hahn, Arjun D. Sharma
  • Patent number: 9089269
    Abstract: System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: July 28, 2015
    Assignees: The Regents of the University of California, Topera, Inc., The United States of America as Represented by the Department of Veterans Affairs, Office of General Counsel
    Inventors: Sanjiv Narayan, Ruchir Sehra
  • Patent number: 9042972
    Abstract: A peak-relevant value device acquires a peak-relevant value (for example, the peak value of an R wave (R peak value)) every cycle from an electrocardiogram acquired. The frequencies of the peak-relevant value acquired as time-series data and the magnitudes for the respective frequencies are analyzed. A peak-relevant value LF calculating device calculates an LF component (peak-relevant value LF component) from the frequency component of the peak-relevant value. An interval acquiring device acquires the interval between characteristic points of the electrocardiographic complex from the electrocardiogram acquired and the frequencies of the feature point interval acquired as time-series data to acquire the magnitudes of the respective frequency component are analyzed.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: May 26, 2015
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Shinya Nagata, Ryuji Nagai, Keiko Yamamoto
  • Publication number: 20150141859
    Abstract: Systems and methods are provided for the study of the cardiac rhythm variability. These systems and methods include the recording of the electrocardiogram (EKG), with subsequent calculation of the duration of the beat-to-beat intervals (i.e., R-R intervals), drawing up of the rhythmograms, and additional systems and methods that include determination of, throughout all observation times within particular intervals included in the recording periods, the average values of the informational entropy of the beta-distribution (AE) of the R-R intervals, the differences between the maximum and minimum values of the informational entropy of the beta-distribution (MDE) of the R-R intervals, the root-mean-square deviations of the informational entropy of the beta-distribution (RMSDE) of the R-R intervals, and/or variation factors of the informational entropy of the beta-distribution (VFE) by means of calculation of the informational entropy of the beta-distribution of the R-R intervals.
    Type: Application
    Filed: November 19, 2013
    Publication date: May 21, 2015
    Inventors: ALEX SANDLER, Sergey Razhev, Alexander Ilyahinsky
  • Publication number: 20150141861
    Abstract: The present invention is directed to a method for determining onset of ventricular arrhythmias using bounded-input bounded-output stability of QT interval (QTI) dynamics. The method of the present invention includes two parts. A first part of the method determines the dependence of each QTI on several prior QTIs and RR intervals (RRI). This determination is represented as an autoregressive model with exogenous input (ARX). A second part of the method determines the BIBO stability of the ARX model in the z-domain. The metrics associated with the first and second parts of the method are then used to predict onset of arrhythmia.
    Type: Application
    Filed: June 5, 2013
    Publication date: May 21, 2015
    Inventors: Natalia Trayanova, Xiaozhong Chen
  • Publication number: 20150141860
    Abstract: A method, system, and device for detection of an arrhythmia, and discrimination between different types of arrhythmia, for example to determine whether to administer an electric shock to the heart, the device comprising a wearable monitor with electrodes that detect the electrical activity of a beating heart, attached to an embedded monitoring system having an amplifier, a microprocessor, a data storage device, and a power supply, all disposed on a substrate having large distal end portions that attach to the electrodes and a narrow intermediate portion that attaches to the monitoring system.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 21, 2015
    Applicant: University of Washington
    Inventor: David Thor Linker
  • Patent number: 9033892
    Abstract: A method for predicting drowsiness is disclosed. By obtaining average heart beat rate values of a driver, and according to the characteristics of the heart beat rate values over a period of time, the method is utilized to determine whether the human being is going to sleep. The method comprises the following steps: detecting a heart beat rate of a driver; calculating a curve of the heart beat rate average during a time interval of X minutes; determining an accumulated length of duration during which the calculated linear regression slope values are smaller than the predetermined slope value Z; determining whether the accumulated length of duration is greater than a time threshold T to generate a drowsiness detecting result; and determining whether to raise an alarm based on the drowsiness detecting result.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: May 19, 2015
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu Jen Su, Yen Hsien Lee, Kuang I Chang