Abstract: The invention relates to a method and device for carrying out a signal-processing viewing of a measurement signal that is correlated with the respiratory activity of an individual, for example, of a measurement signal that is correlated with the respiratory gas. The aim of the invention is to provide solutions with which an improved electronic analysis of the signals that are representative with regard to respiratory activity can be achieved. To this end, the invention provides that viewing results are obtained within the scope of a signal-processing viewing of said measurement signal and make a differentiation between obstructive and central respiratory disorders possible. The viewing results are determined, in particular, while taking into account changes of selected breathing characteristics such as, for example, the change in the ratio of inhalation time to exhalation time.

Abstract: An adapter (1) for an exhaled breath measurement apparatus (2), comprising a first inlet (3) for tidal breathing, a second inlet (4) for air free from one or more component to be measured, through which and a first one-way valve (5) air flows when a test person inhales through the adapter (1) at the first inlet (3), and an outlet (6) for exhaled breath having a second one-way valve (7). A sample tubing (11) is positioned next to the first inlet (3) for tidal breathing for a continuous sample from the exhaled breath immediately inside the adapter (1), upstream the second one-way valve (7) at the outlet (6) for exhaled breath. An exhaled breath measurement apparatus (2) with such adapter (1). A method for measuring exhaled breath during tidal breathing by sampling continuously in an adapter (1) at a first inlet (3) into which a test person breathes, the sampling taking place upstream of an outlet (6) for exhaled breath.

Abstract: An apparatus used in the medical industry, in order to increase transpulmonary pressure and respiratory volumes, to improve inspiratory muscle performance and re-establish the normal pulmonary hyperinflation, through the employment of electronic technology, providing audible, simulated, verbal, human sounding words, that assist, guide and prompt, increasing patient usage. In one embodiment, the Incentive Spirometer uses a capacitive sensing circuit for sensing movement of the float within the tube wall and for obtaining a measurement or reading of the patient's performance with the Incentive Spirometer.

Abstract: The present invention provides a device for use in monitoring a sleep apnoea condition, the device includes a cannula arranged to pass into a mask that is connectable to an airway pressure machine. The cannula may be utilised to administer the test while the mask is utilised to deliver airway pressure.

Abstract: An oral-nasal cannula comprising at least one nasal breath inlet for carbon dioxide (CO2) sampling; and at least one nasal breath inlet for flow measurement, wherein said at least one nasal breath inlet for flow measurement is separated from said at least one nasal breath inlet for CO2 sampling, such that said cannula is configured to facilitate CO2 sampling and flow measurement essentially without cross-interference.

Abstract: A nasal cannula for monitoring symptoms of sleep apnea and hypopnea, including an elongated main body having a main body chamber and first and second nares to be received within first and second nasal passages of a patient's nose and at least one mouthpiece extending to a patient's mouth. The main body chamber communicates with first and second cannula inlet/outlets and each nare and the mouthpiece includes a gas flow passage extending from the nostril or mouth to the main body chamber. At least one nasal gas flow sensor is located in an gas flow passage of at least one of the nares and at least one oral gas flow sensor located in the mouthpiece gas flow passage, preferably in the regions of the gas flow passages adjacent the main body chamber.

Abstract: An active implantable medical device, integrating a spirometric function for the diagnosis of lung diseases is disclosed. The active implantable medical device measures the respiratory activity of a patient to collect a transthoracic impedance signal according to changes in lung volume. The active implantable medical device comprises a spirometer function produces, from the transthoracic impedance signal collected over a respiratory cycle, a characteristic curve that couples of flow values (dV/dt) as a function of pulmonary volume (V) that represents a spirometric characteristic (S) of a patient. An spirometric analysis is performed to deduce from the spirometric characteristic (S) at least one parameter of the patient's pulmonary status and to produce a diagnostic indicator based on the comparison of the at least one parameter with a predetermined reference value.

Abstract: The invention provides a method for obtaining and evaluating spirographic and gas exchange data, comprising measuring a concentration of a breathing gas gc(Vx) for a plurality of volumes Vx of breathing gas mix, wherein the measuring is performed on inhaled breathing gas mix, further comprising determining an apparatus dead space ApDS, of breathing gas mix in the apparatus not taking part in gas exchange, by evaluating the measured concentrations gc(Vx) as a function of the volume V of the inhaled breathing gas mix. The use of inhaled breathing gas mix allows to determine the apparatus dead space, which is an important parameter when evaluating ventilation efficiency and the like. Furthermore, the invention provides a method in which inhalation and exhalation parts of a spirogram are synchronised, by matching features thereof, in order to further improve the accuracy of gas exchange volumes and derived data.

Abstract: A system for sensing respiratory pressure includes a portable pressure transducer configured to be carried by or proximate to a respiratory conduit, such as a breathing circuit or a nasal canula. The portable pressure transducer may removably couple with a pneumotach, in the form of an airway adapter, disposed along the respiratory conduit. The pneumotach may include two pressure ports positioned at opposite sides of an obstruction, which partially blocks flow through a primary conduit of the pneumotach. Corresponding sample conduits of the portable pressure transducer removably couple with the pressure ports. The pressure ports may have sealing elements which are configured to seal against piercing members of the sample conduits upon introduction of the piercing members therethrough. Upon removal of the piercing members, the sealing elements substantially reseal. Methods for using the system are also disclosed.

Abstract: A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.

Abstract: A respiration pattern of a number of respiration cycles is detected and breath intervals (BI) and tidal volume (TVOL) measurements of each of the respiration cycles are respectively determined. An unevenly sampled instantaneous minute ventilation (iMV) signal is produced using the BI and TVOL measurements, and an evenly sampled iMV signal (resampled iMV signal) is produced using the unevenly sampled iMV signal. Disordered breathing is detected based on a comparison between a baseline threshold and the resampled iMV signal.

Abstract: A method of sampling one or more respiratory profile characteristics and monitoring a variety of respiratory profile parameters. The sampled respiratory characteristics include respiratory flow rate, respiratory pressure, and partial pressure of at least one constituent of a patient's respiration. The method detects patient breaths, determines whether each breath is a spontaneous breath or a ventilator-induced breath and calculates various respiratory profile parameters based on the sampled measurements. The method displays the respiratory profile parameters in graphic and numeric forms. Preferably, the method allows a user to select the displayed respiratory profile parameters.

Abstract: A method for measuring lung collapse and for providing information regarding recruitment and successfulness of actions taken to recruit the lung is provided. Alveolar- and proximal pressures are determined at different lung pressures or volumes. Patient airway resistance is calculated combining these measurements with flow measurement. Plotting the resistance against the lung pressure or volume gives a within-breath distribution of the resistance. Increase of this resistance at end-expiration volume or pressure indicates lung collapse.

Abstract: Methods, systems and devices are provided for monitoring respiratory disorders based on monitored factors of a photoplethysmography (PPG) signal that is representative of peripheral blood volume. The monitored factors can be respiratory effort as well as respiratory rate and/or blood oxygen saturation level. The systems and devices may or may not be implanted in a patient.

Abstract: Methods, systems, and devices are provided which include receiving data or providing data, wherein the data regards a physical condition affecting one or more subjects. The data can inform administration of a pharmaceutical composition in response to the physical condition, wherein the pharmaceutical composition is configured to contact pulmonary tissue to treat a pulmonary disease or condition in the one or more subjects. The data regarding the physical condition may be acquired prior to the subject entering an environment where the physical condition exists.

Abstract: An expiratory flow sensor system is disclosed herein. The expiratory flow sensor includes an expiratory channel adapted to transfer an expiratory gas, a fresh gas channel adapted to transfer a fresh gas, and a sensing element disposed within the fresh gas channel so that the sensing element is never directly exposed to the expiratory gas. The sensing element is configured to measure a fresh gas flow rate. The fresh gas flow rate may be implemented to estimate an expiratory flow rate in a manner that minimizes imprecision attributable to sensing element contamination.

Abstract: The functional residual capacity (FRC) value of a subject's lungs determined for each breath is related a volume dilution factor kn and the final FRC value is determined at the point where the volume dilution factor kn reaches a predetermined volume dilution factor value. The determination of the final FRC value can be based on interpolation or extrapolation from a measured breath data series. The volume dilution factor may be normalized value. This is achieved by division of all volume dilution factors with the initially determined volume dilution factor. With normalization, the compartments in which gas concentration change is achieved slowly are referenced with the faster, more effective compartments, thus giving a ventilation profile of the lungs.

Abstract: A method and apparatus for interfacing a plurality of gas measurement systems, including a mainstream and a sidestream gas measurement system, to a host system via an interface unit. The present invention also pertains to a sidestream gas measurement system that output signals emulating the signals output by a mainstream gas measurement system or portion thereof, so that the sidestream gas measurement system can seamlessly communicate with a host system configured to communicate with a mainstream gas measurement system or a portion thereof.

Abstract: A breath biofeedback method and system for encouraging a subject to modify respiration. The system includes a thoracic volume input module measuring thoracic volume data of the subject and a pattern module providing target breathing patterns in communication with a display generator. The display generator producing display information representing a displayable image including a first object having a first position determined as a function of the thoracic volume data and a second object having a second position determined as a function of the target breathing pattern and the thoracic volume data. The displayable image is designed such that when displayed on the display device the displayable image encourages the subject viewing the displayable image to modify respiration.

Abstract: This document discusses, among other things, a system and method for detecting biomedical data for diagnosing sleep disorders of a patient. Biomedical data of the patient can be detected using one or more wireless sensors. The biomedical data can be processed to separate various information including respiration temperature and pressure information. The various information can be wirelessly communicated to a base station coupled to a polysomnograph (PSG) machine configured to display the information for diagnosing sleep disorders.

Abstract: Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and/or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.

Abstract: A bellows-based patient breath-hold monitoring and feedback system for use in intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen where respiratory motion is a problem. Breath-hold monitoring and feedback with the bellows system allows a patient to perform consistent breath-holds at a preselected level, which in turn, optimizes intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen by allowing target lesions to be reliably visualized.

Abstract: This document discusses, among other things, method and apparatus for detecting abnormal respiration activity. Clock pulses can be passed through a first gate when digital airflow information indicates a first respiration state, summed, and compared to a first count threshold, and a respiration activity output can be generated using the comparison.

Abstract: Methods and apparatus for determining leak and respiratory airflow are disclosed. A pressure sensor (34) and a differential pressure sensor (32) have connection with a pneumotach (24) to derive instantaneous mask pressure and airflow respectively. A microcontroller (38) estimates a non-linear conductance of any leak path occurring at a mask (12) as being the low pass filtered instantaneous airflow divided by the low pass filtered square root of the instantaneous pressure. The instantaneous leak flow is then the conductance multiplied by the square root of the instantaneous pressure, and the respiratory airflow is calculated as being the instantaneous airflow minus the instantaneous leak flow. The time constants for the low pass filtering performed by the microcontroller (38) can be dynamically adjusted dependent upon sudden changes in the instantaneous leak flow.

Abstract: A method of sampling one or more respiratory profile characteristics and monitoring a variety of respiratory profile parameters. The sampled respiratory characteristics include respiratory flow rate, respiratory pressure, and partial pressure of at least one constituent of a patient's respiration. The method detects patient breaths, determines whether each breath is a spontaneous breath or a ventilator-induced breath and calculates various respiratory profile parameters based on the sampled measurements. The method displays the respiratory profile parameters in graphic and numeric forms. Preferably, the method allows a user to select the displayed respiratory profile parameters.

Abstract: 1,1,1,2-Tetrafluoroethane (norflurane) is used as a tracer/trace gas for measuring the lung function because of its simple detectability, physiological harmlessness, environmental friendliness and ready availability. Especially advantageous is the possibility of the optical concentration measurement of 1,1,1,2-tetrafluoroethane for the measurement of the lung function and especially for the determination of the FRC during respiration during anesthesia, without cross sensitivity occurring during the measurement with respect to anesthetics.

Abstract: The device comprises:—a tight test enclosure (14) for receiving the animal (16),—a means (20, 21) for thermally regulating the test enclosure (14),—a means (27) for renewing air in the test enclosure (14) at a controlled flow rate,—a pressure sensor (41) for measuring pressure difference between the air in the test enclosure and a reference,—a means (43) for deducing a volume of air inhaled or expired by the animal during one inhalation or expiration from a pressure measurement of the pressure sensor (41), The test enclosure (14) comprises a floor having at least three dry electrodes, insulated from each other, each electrode being intended for collecting an electrical signal resulting from the cardiac activity of the animal (16) when the animal is in contact with the electrode. The device comprises a means (51) for determining an electrocardiogram of the animal (16) by using three electrical signals collected by the at least three electrodes.

Abstract: Pulmonary evaluation device has sensor means adapted to sense fluctuations in a user's lung operation and feedback means, driven by said sensor means, for determining successive values representative of the user's lung fluctuations and adapted to translate said values into appropriate lung-evaluating information. Optionally, the sensor means comprises or forms part of an item suitable to be worn by or carried adjacent the user so as to follow body movements caused by the user's lung operation to evaluate the user's lung operation.

Abstract: A method, system, apparatus and device for the monitoring, diagnosis and evaluation of the state of a dynamic pulmonary system is disclosed. This method and system provides the processing means for receiving sensed and/or simulated data, converting such data into a displayable object format and displaying such objects in a manner such that the interrelationships between the respective variables can be correlated and identified by a user. This invention provides for the rapid cognitive grasp of the overall state of a pulmonary critical function with respect to a dynamic system.

Abstract: A method is disclosed for motivating a user of a spirometry system having a display screen, an air-tube, a flow measurement sensor operatively associated with the air-tube, a display screen, and an associated processor. A motivational animation is displayed on the display screen having a first aspect that reflects a relative evaluation of a determined peak flow rate to a goal value therefor and having a second aspect that reflects a relative evaluation of a determined total flow volume to a goal value therefor. The processor repeatedly updates the motivational animation during the period of use of the spirometer to reflect the degree of achievement of both of the goal values by the user.

Abstract: A sensor for use with a polysomnograph in a sleep lab setting is made reusable by laminating a PVDF film and associated lead contacts within a flexible, moisture-impervious plastic envelope that is hermetically sealed about its periphery. Lead terminals within the envelope are adhered to the metalized surfaces of the PVDP film using a conductive adhesive which inhibits dislodgement of the leads from the sensor even with rough handling and cleaning.

Abstract: A system includes an implantable medical device that includes a trans-thoracic impedance measurement circuit providing a trans-thoracic impedance signal of a subject. A controller is coupled to the trans-thoracic impedance circuit. The controller extracts a respiration signal from the trans-thoracic impedance signal, measures a breathing volume of the subject using the amplitude of the respiration signal and a breathing volume calibration factor, computes an adjusted breathing volume calibration factor using a reference baseline value of the trans-thoracic impedance and a measured baseline value of the trans-thoracic impedance, and computes a calibrated breathing volume using the adjusted breathing volume calibration factor.

Abstract: Methods and apparatus are disclosed for determining the occurrence of a closed or open apnea. Respiratory air flow from a patient is measured to give an air flow signal. The determination of an apnea is performed by applying an oscillatory pressure waveform of known frequency to a patient's airway, calculating a complex quantity representing a patient admittance (12) and comparing its value with ranges (14,16) indicative of open or closed apneas. The method distinguishes open from closed apneas even when the model used to calculate admittance is not based on details of the respiratory apparatus. In addition the patient admittance may be compared with admittance during normal breathing to avoid having to characterize the airway.

Abstract: A device for detecting the condition of flow in a respiration system combines the function of a nonreturn valve with the function of flow measurement in a common device. The device includes a valve arrangement (1) with a valve disk (9) and with a valve body (8), wherein the position of a valve disk (9) in relation to a valve seat (11) is detected. An indicator for a flow and a direction of flow (5), (6) is determined from the position of the valve disk (9). The position of the valve disk (9) can be determined inductively, electrically, electromechanically or optically. The flow and direction of flow (5), (6) determined can be used to control the respiration in a medical device.

Abstract: An airflow signal corresponding to the breathing of the patient is obtained. A section corresponding to inspiration, having a front portion and a middle portion, is found within the airflow signal. A peak value of the front portion is found, which is compared with a value representing the airflow of the middle portion. The presence of resisted breathing is determined based on the comparison between the peak value of the front portion with a value representing the airflow of the middle portion. A baseline value of the airflow signal is found by calculating the mode of values within an airflow signal representing the pressure within a patient's naris. The section corresponding to inspiration is determined by finding peak inspiration and baseline values within a breath and searching from the peak until the baseline is reached to find the section of inspiration.

Abstract: A system and method for sleep monitoring, diagnosing and sensing temperature and pressure for a breathing cycle of a patient including a sensing device suitable for both nasal and oral breath monitoring for measuring respiratory air wave and airflow information during a sleep apnea diagnostic session and processing the acquired air wave and airflow breathing information for input to conventional polysomnography equipment.

Abstract: A window for use in an adapter for an IR gas analyser for analysing breathing gases, where the gases flow through a through-penetrating passageway in the adapter, which includes windows disposed on opposite sides of the passageway so as to enable an IR beam to be sent through the windows and through the passageway containing said breathing gases. Each window is a one-piece structure comprised of plastic material and has a round basic shape that includes a surrounding edge and a central part which is sunken in relation to the surrounding edge and which forms the window through which the IR beams or rays shall be able to pass. A method of producing such a window, by injection moulding a thermoplastic material in a mould where injection of the plastic material is also disclosed.

Abstract: A flow measurement system includes: a respiration monitoring apparatus which measures a flow of a gas flowing through a flow path, to output a measurement value; and a gas monitoring apparatus which samples the gas to measure at least one of a concentration of a component of the gas and a component of the gas and to generate information on the flow of the sampled gas. The measurement value is corrected based on the information.

Abstract: A method is disclosed for motivating a user of a spirometry system 20 having a display screen 12, an air-tube 22, a flow measurement sensor 24 operatively associated with the air-tube 22, a display screen 26, and an associated processor 30. A motivational animation is displayed on the display screen 12 having a first aspect that reflects a relative evaluation of a determined peak flow rate to a goal value therefor and having a second aspect that reflects a relative evaluation of a determined total flow volume to a goal value therefor. The processor 30 repeatedly updates the motivational animation during the period of use of the spirometer to reflect the degree of achievement of both of the goal values by the user.

Abstract: A breath biofeedback method and system for encouraging a subject to modify respiration. The system includes a thoracic volume input module measuring thoracic volume data of the subject and a pattern module providing target breathing patterns in communication with a display generator. The display generator producing display information representing a displayable image including a first object having a first position determined as a function of the thoracic volume data and a second object having a second position determined as a function of the target breathing pattern and the thoracic volume data. The displayable image is designed such that when displayed on the display device the displayable image encourages the subject viewing the displayable image to modify respiration.

Abstract: In order to enable a medical worker to certainly and easily know whether a patient on a home oxygen therapy, who continues to inhale an oxygen-enriched gas at home, performs the inhalation as prescribed, a history of a supply condition of the oxygen-enriched gas supplied to the patient is recorded and held as supply history information, this supply history information is compared with a prescription of the oxygen therapy of the patient to generate patient's compliance information to indicate the degree to which the oxygen therapy is performed in accordance with the prescription, the oxygen concentrating apparatus is constructed to be portable, and a doctor can confirm the patient's compliance information at the time of going to a medical institution regularly.

Abstract: An artificial airway obstruction and pulmonary mechanics measuring device comprising a rigid body chamber having a pressure measuring port and a medical ventilator port; a pressure measuring device coupled to the pressure measuring port; and a ventilator port occlusion device coupleable to the medical ventilator port. A method of manufacturing an artificial airway obstruction and pulmonary mechanics measuring device is included.

Abstract: The present invention is an apnea monitor giving alarm when apnea occurs. It uses new designed gas flow sensor and gas differential flow sensor to detect actual airflow from patients nose and mouth. The gas flow sensor and gas differential flow sensor are evolved from a galvanometer utilizing it's structure for sensitivity. The apnea monitor measures the change of chest volume to detect breathing by a conductive rubber string. The apnea monitor also detects the frequency of baby's movement to predict possible apnea.

Abstract: New applications of unidirectional airflow sensing in devices which measure inspiratory airflow and bidirectional airflow are provided. Such devices can be used for administration of a medication via inhalation, in spirometers and in devices which measure and monitor respiratory ventilation.

Abstract: A measuring system for electronically measuring the volume flow expired and/or inspired by a user, comprises a measuring unit for continuously monitoring the volume flow of air when the user is expiring and/or inspiring, a first memory section for storing data of a reference expiration and/or inspiration volume flow profile and at least a second memory section for storing data of a measured expiration and/or inspiration volume flow profile. A representation of the reference flow profile and the measured flow profile is displayed, which allows a comparison of the profiles.

Abstract: A sensor for use with a polysomnograph in a sleep lab setting is made reusable by laminating a PVDF film and associated lead contacts within a flexible, moisture-impervious plastic envelope that is hermetically sealed about its periphery. Lead terminals within the envelope are adhered to the metalized surfaces of the PVDP film using a conductive adhesive which inhibits dislodgement of the leads from the sensor even with rough handling and cleaning.

Abstract: A method and apparatus for interfacing a plurality of volumetric measurement systems, each of which includes a gas measurement and a flow measurement system, to a host system via an interface unit.

Abstract: A system includes an implantable medical device that includes a trans-thoracic impedance measurement circuit providing a trans-thoracic impedance signal of a subject. A controller is coupled to the trans-thoracic impedance circuit. The controller extracts a respiration signal from the trans-thoracic impedance signal, measures a breathing volume of the subject using the amplitude of the respiration signal and a breathing volume calibration factor, computes an adjusted breathing volume calibration factor using a reference baseline value of the trans-thoracic impedance and a measured baseline value of the trans-thoracic impedance, and computes a calibrated breathing volume using the adjusted breathing volume calibration factor.

Abstract: A self-actuated cylinder comprising a cylinder housing comprising electro-magnetic force generating means to generate electro-magnetic forces, and a piston within the cylinder housing, wherein the electro-magnetic forces act directly on the piston to displace the piston within the cylinder housing. The self-actuated cylinder can be used as an oscillation spirometer to determine air flow, an input impedance or Forced Oscillation pulmonary mechanics.

Abstract: A novel and non-obvious method, system and apparatus for determining respiratory volume flow rate of a subject and associated parameters such as tidal volume, minute volume, and respiratory rate. The method for determining respiratory volume flow rate of a subject can include selecting an airway cavity of the subject, measuring delivery volume flow rate of respiratory gas delivered to the airway cavity, measuring pressure within the airway cavity and calculating a respiratory volume flow rate of the subject using the measured delivery volume flow rate of respiratory gas delivered to the airway cavity and the measured pressure within the airway cavity. The method further can include generating a warning signal selected from the group consisting of an indicator that a respiratory volume flow value is outside of an expected value for the subject and an indicator that an airway cavity measurement value does not conform to an expected value.