Abstract: A waste management system and method of use. The waste management system includes a waste transport device and a waste collection device. The waste transport device includes a generally tubular body, a distal end section configured for disposition and maintenance in a patient's rectum, and a proximal end section including a first connector biased in a sealed position. The waste collection device includes a second connector. The first connector is transitioned to an unsealed position when the first connector is secured to the second connector.

Abstract: A marker delivery device, “adaptor”, for a MRI breast biopsy system is described and claimed. The marker adaptor for the MRI breast biopsy device provides the operator with the ability to easily mark after an MRI biopsy procedure through the biopsy sleeve. The flexible shaft marker snaps into the marking adaptor which creates the oval shape that mates with the inner surface of the sleeve. This locks the orientation of the sleeve and marker, with adaptor, together. The marker adaptor also contains a hard-stop which allows the user to place the biopsy marker in the correct location.

Abstract: Systems and methods that enable harvesting of cartilage from a subject (e.g., a patient) via a harvesting unit that mitigates or eliminates a requirement of dicing and/or separation/division of the cartilage by hand. The harvesting unit employs a power supply to accumulate and cut the cartilage. By employing the harvesting unit, an automatic accumulation and reduction of size for the cartilage is provided, while freeing a person from having to manually dice the cartilage.

Abstract: A surgical treatment apparatus comprises a waterjet configured to fragment tissue and provide intact cells such as stem cells with the fragmented tissue. The intact cells can be used in one or more of many ways such as for genetic or other testing, and the intact cells can be identified as stem cells. In many embodiments, the intact cells comprise stem cells. In many embodiments, a waterjet is configured to fragment tissue. The fragmented tissue can be collected with a filter having pores sized smaller than the tissue fragments. In many embodiments cavitation with a waterjet is used to fragment the tissue comprising the intact stem cells. The waterjet may comprise a waterjet immersed in a liquid comprising water so as to form a plurality of shedding pulses. The plurality of shedding pulses can be generated with a frequency sufficient to fragment the tissue. The shedding pulses can generate cavitations that fragment the tissue.

Abstract: Systems and methods for a reduced-pressure interface for providing reduced pressure through a sealing member to a distribution manifold includes a housing having a flange portion and a cavity wall portion such that the cavity wall portion forms a cavity having a tissue-facing cavity opening. A conduit port is coupled to the cavity wall and has a conduit aperture, such that the conduit port is adapted to receive a reduced-pressure delivery conduit. An attachment device is coupled to a tissue-facing side of the flange portion of the housing such that the attachment device couples the housing to the sealing member. Additionally, a cutting element is at least temporarily coupled to the housing proximate to the tissue-facing cavity opening such that the cutting element is adapted to form an aperture in the sealing member when the cutting element is driven into the sealing member with a driving force.

Abstract: Apparatus and methods for integrating tissue processors and embedding systems. An apparatus, of one aspect, includes a robot. The robot has a work envelope that encompasses a location having a tissue holder and an input of an embedding system. The tissue holder has at least one processed tissue. The robot is configured to transfer the tissue holder from the location to the input of the embedding system. A method, of one aspect, may include moving a robot to a location having a tissue holder. The tissue holder may have at least one processed tissue. The robot may engage with the tissue holder at the location. The robot may move the tissue holder from the location to an input to an embedding system. The robot may disengage from the tissue holder at the input to the embedding system. Other methods, apparatus, and systems are also disclosed.

Abstract: Tool mount adaptors for interfacing a medical instrument with a medical insertion device are provided. The tool mount adaptor includes a collar for holding a medical instrument wherein the tool mount adaptor is releasably attachable to the medical insertion device. Cannula holder assemblies for a medical insertion device are also provided. The cannula holder assembly includes: (a) a cannula track; and (b) a cannula carriage slideably mounted on the cannula track comprising a cannula holder mount and a demobilizer. Medical insertion devices comprising the tool mount adaptors and/or cannula holder assemblies are also provided together with methods of using the medical insertion devices in diagnostic and/or therapeutic applications.

Abstract: An impact biopsy device is disclosed. The impact biopsy device may be configured to displace various cutting elements, such as an outer tubular member and cutting element and a cannula to sever a tissue sample from a patient. The impact biopsy device may comprise an actuation system configured to transfer displacement or force to the cutting elements by the impact of an element on another element.

Abstract: A “one-step”, single-handed device for obtaining small, precise volumes of fluid from animals is able to quickly and easily draw a fluid sample. The device comprises an extraction component and a collection component that are coupled together and disposed along a grip handle. The user manipulates the device so as to initiate the extraction of the fluid, and then collect the fluid in a component that can quickly and easily be removed from the grip handle—allowing the handle to be re-loaded and used again and again. The extraction component may comprise a hypodermic needle and the collection component may comprise a pre-calibrated pipette, where the pipette is positioned directly behind the needle and will thus draw the extracted fluid into a pre-sized chamber within the pipette.

Abstract: A minimally-invasive tissue retrieval device includes a flexible, liquid-impermeable bag with wires attached to the interior surface by an attachment mechanism that releases the wires when pulled. The wires extend into the bag from opposing sides of the bag opening, down to the bottom of the bag. Ends of the wires extend vertically upward out of the opening and are attachable to a wire retracting element rotatably attached to a housing, such that rotation of the retracting element relative to the housing winds the wires about the retracting element, pulling them away from the interior surface, and upward towards the opening. The bag is insertable into a surgical cavity, where a tissue sample is inserted into the bag. Rotatably-retracting the wires cuts through the tissue, which can then be removed in sections through the opening positioned outside the surgical cavity to prevent the spread of tissue fragments.

Abstract: Assembly (10) for positioning an electrode assembly (16) for radiofrequency ablation, comprising a first linear motion guide (11) defining a first axis of motion (103) and comprising a first carriage (111) operable to move along the first axis of motion (103), an XY positioner (12) operable to move a second carriage (123) in a two-dimensional space defined by a second axis of motion (104) and a third axis (105) orthogonal to the second axis of motion. The XY positioner is positioned relative to the first linear motion guide (11) such that the second axis of motion and the third axis are orthogonal to the first axis of motion (103). A first coupling means (125, 14) couples the electrode assembly (16) to the second carriage (123). A second linear motion guide (13) defining a fourth axis of motion (106) is disposed such that the fourth axis of motion is parallel to the second axis of motion (104).

Abstract: A high intensity focused ultrasound positioning mechanism (100, 200, 310) for positioning a high intensity focused ultrasound transducer (292, 304), the mechanism comprising: —a positioning plate (108, 308) adapted for receiving the high intensity focused ultrasound transducer; —a mechanism support (174) adapted for mounting the positioning mechanism; —a plurality of rods (110, 112, 114, 116, 118, 120, 210, 212, 214, 216, 218, 220), wherein each rod has a first end and an second end, wherein the first end of each rod forms a separate ball joint (122, 124, 126, 128, 130, 132, 222, 224, 226, 228, 230, 232) with the positioning plate; and —a plurality of linear drives (146, 148, 150, 246, 248, 250, 252, 254), wherein the plurality of linear drives are mounted to the mechanism support, wherein each of the linear drives comprises a drive block (164, 166, 168, 264, 266, 268, 270, 272), wherein the second end of each of the plurality of rods forms a separate ball joint (134, 136, 138, 140, 142, 144, 234, 236, 238, 2

Abstract: This invention provides a non-invasive diagnosis system that is not only capable of producing high-resolution, three-dimensional images of abnormalities of tissue growth inside the body but, it can also detect the type of abnormalities and their location using multispectral imaging techniques. It is possible to provide a portable, non-invasive device that is handheld and with which women may use to screen themselves for early detection of breast cancer without the need to visit a physician. As the present invention uses broadband sources and/or multiple coherent sources, secondary factors such as oxygen metabolism or blood volume associated with the cancer tissues could also be detected to provide further verification of the type. This invention would raise the accuracy of diagnosis and reduce the rate of false positives and false negatives.

Abstract: An endoscopic forceps is provided and includes a housing having a shaft that extends therefrom. An end effector assembly is operatively connected to a distal end of the shaft and includes a pair of pivotably coupled first and second jaw members. One of the jaw members is movable relative to the other jaw member. A drive mechanism includes a driving structure in operative communication with a cam slot operably disposed on one of the first and second jaw members. The driving structure includes a detent.

Abstract: A swiveling intravenous therapy tubing connection system for easy rotational adjustment of an intravenous tubing line between a sterile container and a catheter used to administer a fluid to a patient features the sterile container which is a sterile intravenous fluid container and the catheter which is an intravenous therapy catheter located in the patient. The system features a length of intravenous therapy tubing having a female quick-connect swivel tubing connector located on a tubing first end and a quick-connect double swivel tubing connector located on a tubing second end. The female quick-connect swivel tubing connector is rotationally connected to a first mated male swivel tubing connector located on an intravenous fluid outlet of the intravenous fluid container. The quick-connect double swivel tubing connector is rotationally connected to a second mated male swivel tubing connector located on an intravenous fluid inlet of the catheter.

Abstract: A syringe assembly configured to urge soft tissue out of a surgical path includes a syringe, an elongate support member and a securing member. The syringe includes a barrel, a needle with a needle tip and a plunger movably mounted in the syringe barrel. The syringe defines a longitudinal axis. The elongated support member has a proximal end, a distal end and an arcuate-shaped cross-section. The securing member is fixed near the proximal end of the elongate support member. The securing member is configured to attach the elongate support member to the syringe. A support length is defined between the securing member and the distal end and a tip length is defined between the securing member and the needle tip when the support member is mounted to the syringe. The tip length is greater than the support length when the syringe assembly is in an injection configuration.

Abstract: A bone marrow aspiration device and associated method includes an introducer needle and an aspiration needle. The introducer needle includes an introducer cannula and a removable introducer stylet that includes a sharp tip to penetrate bone. The aspiration needle includes an optionally flexible aspiration cannula and a blunt stylet. The aspiration needle is receivable in the introducer cannula when the introducer stylet is removed from the introducer needle. The aspiration cannula forms a channel for aspirating bone marrow when the stylet is removed. The aspiration device also includes a locking mechanism to lock the aspiration cannula to the introducer cannula when the aspiration cannula is received in the introducer cannula, whereby the aspiration cannula can be advanced distally relative to the introducer cannula in a controlled manner, and whereby pulling the aspiration cannula proximally causes the introducer cannula to move proximally with the aspiration cannula.

Abstract: An actuator for a medical device includes a housing, a driving unit mounted in the housing, a first moving unit slidably mounted in the housing and movable by the driving unit. The first moving unit includes a movable first car, an spring with two ends thereof abutting the housing and first car, respectively, and a lock formed between the driving unit and first car. The lock includes a first snap and a first protrusion detachably engagable with the first snap. One of the first snap and first protrusion is formed on the first car, and the other is formed on the driving unit. When the first protrusion disengages from the first snap, the spring moves the first car relative to the housing.

Abstract: A specimen retrieval device includes an applicator. A specimen retrieval pouch is operably disposed within the applicator and deployable therefrom. The specimen retrieval pouch defines a longitudinal axis therethrough and includes a closed bottom portion and an open upper portion. The closed bottom portion includes a plurality of spikes configured to grasp a specimen positioned within the confines closed bottom portion. The upper closed portion includes one or more axial folds that are movable from a folded configuration to an unfolded configuration when a predetermined force is applied to a portion of the specimen retrieval pouch.

Abstract: A shaft for a medical instrument includes a controlled curvable portion or a hinge, an uncontrolled flexible portion, and a shaft coupling device for the releasable mechanical connection of the shaft to a maneuvering device.

Abstract: A method of securing a biopsy marker within a biopsy site includes depositing a marker element within a biopsy site and fixing the marker element within the biopsy site by injecting a securing agent within the biopsy site. Delivery devices for delivering the securing agent to the biopsy site are also disclosed.

Abstract: A method using 2D multi-spectral imaging (2DMSI) for MRI imaging of a metallic object (such as a biopsy needle) and region surrounding the metallic object within an imaging field of view of an MRI apparatus includes segmenting the imaging field-of-view into spatial-spectral bins, where the segmenting is based on off-resonance frequency induced by the metallic object and slice location; selectively exciting each frequency bin of the spatial-spectral bins by inverting a slice selection gradient between excitation and refocusing pulses; performing repeated acquisition with different radiofrequency modulations to produce acquired images of adjacent bins; composing a 2DMSI image by root-sum-of-squares combination of the acquired images of adjacent bins; and highlighting in the 2DMSI image an area of furthest off-resonance bins based on 2DMSI off-resonance information by thresholding image intensity in frequency bins, thereby indicating a contour of the metallic object.

Abstract: Among other things, there is disclosed a biopsy needle system in which the needle is capable of obtaining more than one length of sample. Generally, the needle includes an inner stylet, an outer cannula, and a handle connected to the stylet and cannula. The stylet has a notch that is extendable from the cannula to accommodate a tissue sample. An insert member is provided for attachment to the handle to make the amount of exposed notch smaller. Consequently, when the insert member is not attached to the handle, the needle can obtain a larger sample of tissue, and when the insert member is attached to the handle, the needle can obtain a smaller sample of tissue.

Abstract: A biopsy needle for collecting a tissue specimen includes an outer cannula that is at least partially received within a handle housing and an inner tube received within the outer cannula and configured to receive a stylet. A snare coil is attached between the inner tube and the outer cannula and a movable base is disposed within the handle housing. The outer cannula is fixedly coupled to the base and the movable base is axially movable within the handle housing. An inner driven structure that is coupled to the inner tube is configured to travel axially across an upper surface of the movable base. The coupling between the inner driven structure and the inner tube is such that the axial driving of the inner driven structure imparts rotation to the inner tube relative to the outer cannula.

Abstract: A variety of steerable needles, lancets, trocars, stylets, cannulas and systems are provided for examining, diagnosing, treating, or removing tissue from a patient. The steerable needles, trocars, stylets, cannulas and systems also provide a platform for delivery of target materials, such as therapeutics, biologics, polymes, glues, etc., to a target site. An embodiment of the invention includes a steerable device for use in accessing target site in a patient comprising: a steerable member adapted to penetrate tissue; and a steering mechanism adapted to be operated by a user to apply a bending force to bend the steerable member to access the target site.

Abstract: A sampling system for an individual to self-collect sample form mucous tissue is disclosed here. The collecting device has a flexible shaft having a handle at one end, and a sample collecting element removably connectable with the other end of the shaft and operable to collect a cell sample from mucous tissue of an individual. The collecting element includes an RFID tag for tracking the device and the sample once it is collected onto the collecting element. The system includes a sealable unit to store the sample collecting element having a cell sample thereon.

Abstract: A full-core biopsy device comprises an outer cannula hub with an outer cannula coupled at a proximal end to the hub, the outer cannula with a tissue slicing feature defined at the distal tip configured for cutting tissue. The device further comprises an inner member hub and an inner member coaxially disposed within the outer cannula and coupled at a proximal end to the inner member hub. The inner member includes a tubular body, an inner member tip at an opposite distal end thereof and an elongated scoop portion defined between the tubular body and tip. The distal ends of the outer cannula and the scoop portion of the inner member define cooperating forcing cone features.

Abstract: A suture loop assembly is provided for securing a specimen collection bag in a closed condition. The suture loop assembly generally includes a length of suture material forming a distal loop and a one-way ferrule for securing the distal loop in a closed condition about an upper end of the specimen collection bag. A specimen retrieval device is also provided for use with the suture loop assembly.

Abstract: A biopsy device includes a lateral member; a gun mount configured to support a biopsy gun, the gun mount being connected to the lateral member and movable along a first axis with respect to the lateral member, and a sensor which detects a position of the gun mount along the first axis with respect to the lateral member and generates positional data which is provided to an interface module. The gun mount can also be reconfigured in orientations which are offset in a dimension which is orthogonal to the first axis, orientations rotationally offset about the first axis or an axis parallel to the first axis. The lateral member can be in right hand and left hand orientations. Various sensors detect these reconfigurations and provide corresponding data to the interface module for additional calculations and display.

Abstract: A biopsy needle surrounded by a peel away sheath chemically impregnated with a blood detection composition enabling a user (e.g., a surgeon) to accurately and timely determine the existence of a blood pooling or hematoma when passing an implantable (e.g., deep brain stimulation probes) or non-implantable (e.g., biopsy needle) device into a region of the subject's body (e.g., a brain) to gather tissue for further analysis. A biopsy needle may be provided wherein the needle is tightly surrounded by a peel-away sheath that is chemically impregnated with a blood detection composition. The surgeon may insert the biopsy needle into the subject and peel away the chemically impregnated sheath in order to assess whether or not a blood pooling or hematoma exists, and act immediately to address the blood pooling or hematoma.

Abstract: A cell culture transferring instrument includes a cylindrical body held by an operator not shown in the drawing, a plunger inserted through the interior of the cylindrical body, a plurality of support members connected to a distal end of the plunger, and an adsorbent capable of adsorbing a sheet-shaped cell culture held by the support members. The support members in contact with the distal end of the cylindrical body are elastically deformed by displacing the plunger toward the proximal end side with respect to the cylindrical body in a state in which the sheet-shaped cell culture is adsorbed to the adsorbent, whereby the adsorbent and the sheet-shaped cell culture are deformed and housed in a housing hole in the cylindrical body.

Abstract: A rectal catheter is configured for improved pediatric care. The catheter includes a member that terminates into a rounded tip, a plug mounted about the member, the plug being made of a moldable material, a balloon mounted about the member between the rounded tip and the plug, a conduit that fluidly communicates with the balloon and that extends from the member to enable a pressure source to be operatively connected to the balloon to inflate the balloon, and a pressure relief valve operatively connected to the conduit, the pressure relief valve being configured to open the conduit to atmosphere pressure in response to a pressure in the conduit reaching a predetermined pressure. The predetermined pressure is selected to attenuate significantly risk of bowel perforation in pediatric patients.

Abstract: Systems and methods for a reduced-pressure interface for providing reduced pressure through a sealing member to a distribution manifold includes a housing having a flange portion and a cavity wall portion such that the cavity wall portion forms a cavity having a tissue-facing cavity opening. A conduit port is coupled to the cavity wall and has a conduit aperture, such that the conduit port is adapted to receive a reduced-pressure delivery conduit. An attachment device is coupled to a tissue-facing side of the flange portion of the housing such that the attachment device couples the housing to the sealing member. Additionally, a cutting element is at least temporarily coupled to the housing proximate to the tissue-facing cavity opening such that the cutting element is adapted to form an aperture in the sealing member when the cutting element is driven into the sealing member with a driving force.

Abstract: A disposable unit for a biopsy device includes a hollow needle configured to define a longitudinal path. A sample-receiving device having a cavity is configured to move in the hollow needle along the longitudinal path between an extended position and a retracted position. A transport device is configured to move the sample-receiving device in the hollow needle between the extended position and the retracted position. The transport device includes a bendable elongate element having a proximal portion and a distal end, the distal end being connected to the sample-receiving device. The bendable elongate element has a tooth surface that is engaged by a rotatable gear. A coiling device is configured to coil the proximal portion of the bendable elongate element as the sample-receiving device is moved linearly along the longitudinal path from the extended position to the retracted position by operation of the rotatable gear.

Abstract: Provided herein are improved solid phase micro-extraction (SPME) devices, systems comprising such devices, and methods of use and manufacture thereof. In particular, SPME devices provided herein are configured to prevent damage (e.g., to the device and/or to a system in which they are employed) incurred, for example, through user error.

Abstract: A biopsy needle comprises a first lumen open to a tissue penetrating distal tip of the needle for receiving a tissue sample therein and a second lumen in combination with a filter separating the first and second lumens from one another, the filter being configured to permit fluids to pass therethrough while preventing the sampled tissue from passing therethrough.

Abstract: This application discloses aspiration/biopsy needle apparatus, devices containing these needle apparatus, and methods using these needle apparatus and devices for aspiration or biopsy of samples, in particular biological samples from mammalian subjects. The novel aspiration/biopsy needle systems can find wide applications in the manufacture of fine needle aspiration (FNA)/biopsy devices for convenient cell harvesting and tissue sampling and analysis.

Abstract: A laser operation device includes an elongated catheter, a light irradiator configured to irradiate a laser in front of a tip of the catheter, a lens disposed at a front of the light irradiator and allowing the laser to pass therethrough, a wire configured to steering the lens by pulling one side of the lens, and an elastic body configured to give an elastic force to restore the lens against a tension of the wire, wherein when the lens is steered, the laser passes through the lens and is refracted.

Abstract: A device for containing bone graft material comprises a body including an inner sleeve extending longitudinally from a proximal end to a distal end and an outer sleeve surrounding the inner sleeve and extending longitudinally from a proximal end to a distal end such that a bone graft collecting space is formed therebetween.

Abstract: An endoscope treatment tool includes a sheath; a support part; a pair of forceps members that are arranged in front of the sheath and are supported so as to be relatively rotatable around a rotation shaft provided at the support part; a linear member that is inserted through the sheath so as to be capable of advancing into and retracting from the sheath, brings opposed surfaces, which are respectively provided closer to distal end sides of the pair of forceps members than the rotation shaft, closer to each other as the linear member is separated from the rotation shaft, and separates the pair of opposed surfaces from each other as the linear member approaches the rotation shaft; an elastic member that is supported by the linear member or the support part; and a locking portion that is provided on the linear member or the forceps members.

Abstract: Among other things, there are disclosed embodiments of full-core biopsy needles having an outer needle component and a middle cannula through a lumen in the outer component, through which a mandrel may be placed. The outer component includes an internal boss that reduces its internal diameter, and the cannula includes fingers that extend distally. When the needle is inserted for biopsy, tissue enters the outer component and cannula. Moving the cannula forward causes the fingers to engage a surface of the internal boss, resulting in the fingers curving into the tissue. The fingers pinch the tissue while reducing or eliminating compression of the sample to provide an easier removal of the tissue from adjacent tissue, as well as providing a block or backstop keeping the tissue within the needle. Gaps are provided between the fingers to further reduce damage to the tissue sample.

Abstract: The disclosure provides a release mechanism, method of manufacturing, and method of releasing a medical device. The mechanism comprises a generally elongate shaft, an actuating member receivable in the elongate shaft, the actuating member having an interlocking position and a releasing position, and at least two opposed arms at a distal end of the elongate shaft, biased to open relative to each other, each arm comprising a gripping portion at a distal end, and at least one interlocking member. The gripping portions of the arms may define a hollow space for holding a device. The interlocking member of each arm is longitudinally spaced from the interlocking member of any other arm and extends circumferentially around the actuating member. The actuating member is longitudinally retractable from the interlocking position to the releasing position to enable the arms to open for releasing a medical device from the gripping portions.

Abstract: The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.

Abstract: A biopsy device and method are provided for obtaining a tissue sample, such as a breast tissue biopsy sample. The biopsy device may include an outer cannula having a distal piercing tip, a cutter lumen, a side tissue port communicating with the cutter lumen, and at least one fluid passageway disposed distally of the side tissue port. The inner cutter may be advanced in the cutter lumen past the side tissue port to sever a tissue sample. After the tissue sample is severed, and before the inner cutter is retracted proximally of the side tissue port, the cutter may be used to alternately cover and uncover the fluid passageway disposed distally of the side tissue.

Abstract: The present invention comprises methods and devices comprising a scraping element used to contact circumferentially and longitudinally the surface walls of the uterine cavity to provide for broad contact of the intended surface with the device, resulting in attainment of a sufficient volume and comprehensive tissue sample for analysis as an endometrial biopsy or screening uterine cancer. The device may provide for a reservoir for the obtained sample to be contained when removing from the uterine cavity, cervical canal, and vagina. The device may be comprised of a detachable means or be of a material that allows the user to cut the sampling head of the device for placement in collection means to maximize the amount of tissue or cells being sent to the laboratory for analysis.

Abstract: A specimen retrieval pouch (pouch) is provided. The pouch including a closed bottom portion, an open upper portion and an elongated tube operably coupled to an interior wall of the pouch. The elongated tube has a plurality of openings positioned along a length thereof. A suture accessible at a proximal end of the pouch is positioned within the elongated tube and extends past a distal end thereof. The suture is movable within the elongated tube and relative to the pouch. The suture has either a needle or a loop at a distal end thereof for attaching to tissue and subsequently drawing the tissue into the pouch when the suture is pulled. One or more reinforced tabs are operably disposed on the pouch. The reinforced tab(s) is/are configured to be grasped by a user to provide a counter pull force as the suture is being pulled through the elongated tube.

Abstract: A method of securing a biopsy marker within a biopsy site includes depositing a marker element within a biopsy site and fixing the marker element within the biopsy site by injecting a securing agent within the biopsy site. Delivery devices for delivering the securing agent to the biopsy site are also disclosed.

Abstract: An echogenic needle and a method of using the needle with an ultrasound machine, in which the needle has a turbulence inducing member positioned within the hollow body of the needle towards the tip end of the needle. The turbulence inducing member is preferably be a reamer. When fluid media passes through the flow path in the hollow body of the needle, the needle induces turbulent flow in the fluid exiting the tip of the needle. This turbulent flow is visible in color on an output display of the ultrasound machine using a color Doppler feature, and is helpful for determining the location of the tip of the needle in an image on the ultrasound display. The tip of the needle may be beveled or blunt. The turbulence inducing member may partially extend from the distal end of the needle and may be of different configurations.

Abstract: Disclosed is a method of collecting cells including the steps of: preparing a processed-bone comprising a bone extracted from a living body, a covering agent and first and second holes, wherein an outer surface of the bone is covered with the covering agent attached to the outer surface of the bone, and the first and second holes penetrate through the covering agent and the outer surface of the bone into the interior of the bone; introducing a liquid into the processed-bone from the first hole; and collecting a cell-containing liquid from the second hole.

Abstract: A surgical instrument includes a movable member having a proximal portion, the movable member defining an opening at the proximal portion. The instrument includes a stationary member defining an aperture. The stationary member is arranged relative to the movable member with a close fit between the stationary member and the movable member such that aspiration occurs through the movable member substantially only during a portion of a repetitive motion of the movable member. The instrument includes a surgical handpiece coupled to the movable member and the stationary member to provide suction and motion to the movable member.