Abstract: Described herein is a circumcision device including a support having a glans penis locating member mountable thereto. The support is provided with at least one pillar that includes a proximal end and a distal end, the distal end being fastened to a crush plate. The pillar facilitates movement of the crush plate relative to the support. A locking device is moveable between a locked position and an unlocked position, such that axial movement of the pillar is inhibited in the locked position and enabled in the unlocked position. The locking device is at least partially hidden by the support. A blocking device is interposed between the support and the crush plate to block movement of the crush plate towards the support past a predefined point to inhibit the locking device from becoming exposed.

Abstract: The present invention provides a biopsy rotary cutting device, which comprises a dynamic sealing structure(4) arranged outside an inner cutting cannula(3); the dynamic sealing structure(4) forms a cavity outside the inner cutting cannula(3); the inner cutting cannula(3) comprises a first tube section(31) and a second tube section(32) that are arranged in sequence along the axial direction of the inner cutting cannula(3); the outer diameter of the second tube section(32) is smaller than that of the first tube section(31); a sealing ring(43) is arranged inside the dynamic sealing structure(4); the cavity comprises a first cavity(41) and a second cavity(42); when the inner cutting cannula(3) moves to a first position along its axial direction, the sealing ring(43) is located at the outer side of the second tube section(32); and there is an inter-cavity gap(46) between the sealing ring(43) and the second tube section(32) to realize communication between the first cavity(41) and the second cavity(42).

Abstract: The embodiments presented herein present a single needle core biopsy instrument and modification required that convert the single needle core biopsy instrument to a dual needle core biopsy instrument. Depending on the design, the dual needle core biopsy instrument includes a dual cannula component that facilitates the simultaneous extraction of tissue or bone specimens.

Abstract: A tissue collection device including a biopsy needle support arrangement to support a biopsy needle so that a tissue compartment in the biopsy needle may be located at a collection position. The tissue collection device includes a carrier medium adapted to adhere to and carry a tissue sample deposited thereon and adapted to be arranged at a deposition position permanently spaced from the collection position. The tissue collection device includes a swiping element adapted to swipe sideward relative to the longitudinal direction through the tissue compartment located at the collection position and in the direction of the deposition position in order to thereby move a tissue sample from the tissue compartment to the carrier medium and to thereby press the tissue sample onto the carrier medium so that the tissue sample is deposited on the carrier medium.

Abstract: Certain aspects relate to a handle mechanism that permits control of linear motion of a shaft secured within the handle via two different interfaces for actuating the linear motion. In some aspects, a rotational interface can allow for fine control linear positioning of the shaft, for example by allowing a user to rotate the rotational interface to extend or retract the shaft. In some aspects, a plunging interface can enable a faster linear motion, for example by implementing a biasing mechanism that releases to drive rapid linear motion.

Abstract: A tissue resecting instrument includes a drive assembly coupled to an inner cutting shaft and configured to drive translation and/or rotation of the inner cutting shaft, a trigger coupled to the drive assembly and configured for manual actuation to drive the drive assembly, a vacuum generator configured to generate vacuum to suction cut tissue through the inner cutting shaft and into the vacuum generator, and a tissue collection cartridge configured to engage the housing. The tissue collection cartridge defines a port configured to communicate with the vacuum generator such that the vacuum generator urges cut tissue from the vacuum generator through the port into the tissue collection cartridge. The tissue collection cartridge may include at least one histological agent disposed therein, may include a fill indicator configured to indicate a fill level of tissue within the tissue collection cartridge, and/or may include a latch configured to seal the port closed.

Abstract: A biopsy device for percutaneous tissue removal includes an elongated housing having an operational axis, a stylet hub slidably mounted in the housing, where the stylet hub is movable relative to the housing between a proximal, armed position, and a distal, fired position, the stylet hub having a stylet strike, a cannula hub slidably mounted in the housing alongside the stylet hub, and a spring-biased arming member. The cannula hub is movable relative to the housing between a proximal, armed position, and a distal, fired position. The arming member is moveably mounted to the housing proximal of the respective stylet and cannula hubs, and configured for manually-actuated movement from a relaxed, extended position to a loaded, compressed position to define a compressive arming stroke. The biopsy device also includes an arming member biasing spring that restores the arming member from the compressed position to the extended position.

Abstract: A syringe mixing system is provided for housing and mixing contents between at least two syringes. In some embodiments, a syringe coupler is provided that receives first and second syringes and includes a valve member that is convertible between a closed position and an open position. Retention systems for preventing or inhibiting removal of at least one syringe after use are also provided.

Abstract: The present disclosure relates to a cap for protecting an imaging instrument from damage caused by impact or poor handling. Exemplary devices can include a rigid outer shell and soft inner lining surrounding a distal tip of the instrument, to be applied between instrument use, and during instrument transport, disinfection, sterilization, and storage.

Abstract: A system and method for collecting bone marrow includes a trocar component having an upper handle and an elongate shaft depending from the handle, the shaft having a sharp cutting edge at a lower tip thereof. An introducer component includes a lower handle having an inlet formed therethrough and an introducer cannula communicably connected to the inlet and depending from the lower handle. The introducer cannula has an open distal end. The harvesting component includes a support hub having an aspiration port and a harvesting cannula communicably connected to the aspiration port and depending from the support hub. The trocar and introducer components are introduced into the bone marrow and the trocar component is replaced by the harvesting component.

Abstract: An electrosurgical probe for ablating tissue includes an elongated shaft having an axis and a distal end. An electrically insulating housing at the distal end of the shaft has a window, and an interior channel in the shaft extends through the housing to the window. The window faces laterally relative to the axis, and a moveable member with a blade-like electrode edge is disposed within the window. A motor drives the energized electrode edge axially in the window to ablate tissue.

Abstract: A biopsy device includes a cannula and a specimen collector. The cannula has a proximal end and a longitudinal axis. The specimen collector contains the proximal end of the cannula. The specimen collector has a removable sample receiving cartridge that is removable along the longitudinal axis of the cannula to expose the proximal end of the cannula.

Abstract: Certain aspects relate to biopsy apparatuses, systems and techniques for biopsy using a biopsy pattern. Some aspects relate to moving a distal portion of a medical instrument to one or more sample locations of the biopsy pattern and guiding the instrument to obtain tissue samples from the sample locations within the biopsy pattern. Some aspects relate to obtaining the biopsy pattern and adjusting the sample locations within the biopsy pattern based on various factors such as anatomical features.

Abstract: A biopsy system includes a biopsy device, a control module, and a tissue transport tube. The biopsy device includes a probe, a needle, a cutter, and a transport valve. The needle extends distally from the probe. The cutter is movable relative to the needle and defines a cutter lumen. The holster is configured to couple to the probe. The transport valve is in communication with the cutter lumen. The control module is in communication with the biopsy device and includes a sample management assembly configured to receive one or more tissue samples severed by the cutter. The transport tube extends between the sample management assembly and the biopsy device. The transport tube is in communication with the transport valve such that the transport tube is configured to receive the one or more tissue samples severed by the cutter.

Abstract: A minimally invasive tissue incision system for creating joint capsulotomies and releasing/incising various tissues, tendons, and fibrous band structures is described. The system contains a penetrating needle which is retractable so as to expose a cutting element, and which may be used as a penetrating needle to pierce the skin and other soft tissue structures. The cutting element provided within the penetrating needle may be used to incise subsequent tissue structures after the initial penetration. The system facilitates such procedures by providing the cutting element with the confines of the needle which provides safe introduction of the cutting element directly to the site via the needle.

Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.

Abstract: An access assembly includes an instrument valve housing defining a cavity, and a valve assembly. The valve assembly includes a flange seal member, a seal assembly, a centering mechanism, and a retainer frame assembly. The flange seal member includes an arcuate portion configured to adjustably engage first and second surfaces of the instrument valve housing in a sealing relation. The centering mechanism is configured to bias the valve assembly towards a generally centered position within the cavity. The centering mechanism includes a plurality of coils including inner coil portions operatively secured with the seal assembly, and outer coil portions configured to engage the first surface of the instrument valve housing. The retainer frame assembly includes first and second members. The inner coil portion of the centering mechanism is disposed between seal assembly and the second member of the retainer frame assembly.

Abstract: The present disclosure relates to an occluder pushing device and an occluder delivery system, wherein the pushing device includes a pushing component and a handle. The pushing component includes a pushing tube and a traction element slidably inserted into the pushing tube. The handle is fixedly connected to a proximal end of the pushing tube and internally provided with a moving component and a locking component. The moving component includes a translation mechanism and a rotation mechanism, where the translation mechanism is used to drive the traction element to move axially inside the pushing tube, and the rotation mechanism is used to drive the traction element to rotate axially inside the pushing tube. The locking component is used to lock relative positions of the traction element and the pushing tube, and the rotation mechanism includes a locking structure for locking or releasing linkage between the rotation mechanism and the traction element.

Abstract: A system for performing a minimally invasive percutaneous procedure comprises a medical device comprising a hydrogel delivery needle (4) with a tip and a hydrogel outlet (6), an injectable, shear-thinning, self-healing viscoelastic hydrogel that exhibits a storage modulus (G?) of at least 600 Pa, and a tan ? (G?/G) from 0.1 to 0.6 in dynamic viscoelasticity measured by a rheometer at 1 Hz and 1% strain rate at 25° C. The system may also comprise a coaxial cannula (2) having a lumen configured for receipt of the hydrogel delivery needle (4), wherein the hydrogel delivery needle comprises an adjustable positioning mechanism (8) configured to limit the advancement depth of the hydrogel delivery needle through the coaxial cannula to a predetermined depth distal to a distal-most end of the coaxial cannula.

Abstract: Devices and methods may allow for the removal of material from a remote location in the vasculature. In an example of such a remote location, the device may be used in the vasculature of a lower extremity in combination with an external cuff. The external cuff may create a dam preventing material from flowing throughout the body. With the external cuff in place, the device of the present disclosure may be utilized to suction the material from the vasculature while rotating the catheter to assist in the removal of the material.

Abstract: Apparatus and methods are provided to penetrate a bone and associated bone marrow using a powered driver. The powered driver is operable to insert an intraosseous device into a bone and associated bone marrow. The powered driver may include a housing having a distal end and a proximal end; a drive shaft having a first end disposed within the housing; a motor disposed within the housing and rotatably engaged with the drive shaft; a power supply to supply power to the motor; and a trigger assembly to activate the motor to rotate the drive shaft. A light may be connected to the power supply and operable to illuminate an insertion site for the intraosseous device.

Abstract: An apparatus and method for penetrating bone marrow is provided. The apparatus may include a housing such as a handheld body, a penetrator assembly, a connector that releasably attaches the penetrator assembly to a drill shaft, a gear mechanism, a motor and a power supply and associated circuitry operable to power the motor. The penetrator assembly may include a removable inner trocar and an outer penetrator or needle. It may also include a grooved trocar that allows bone chips to be expelled as the apparatus is inserted into bone marrow. Various connectors are provided to attach the penetrator assembly to the drill shaft.

Abstract: An end effector assembly of a tissue-resecting device includes an outer shaft, a drive wire, the distal cutting tip, a hub housing, and a driver. The outer shaft includes a distal end portion defining a window therethrough. The drive wire extends through the outer shaft. The distal cutting tip is disposed within the outer shaft and engaged with the distal end portion of the drive wire. The distal cutting tip at least partially overlaps the window. The hub housing is engaged with the proximal end portion of the outer shaft. The driver is disposed within the hub housing and engaged with the proximal end portion of the drive wire to driver rotation of the drive wire and distal cutting tip within and relative to the outer shaft. The driver defines an internal lumen and at least one lateral opening disposed in communication with the internal lumen.

Abstract: According to an aspect of the present disclosure, an end effector for use with a surgical device is provided. The end effector includes a drive assembly, a driver, a needle assembly, and a follower. The drive assembly includes a first helical groove. Rotation of the drive assembly in a first direction causes distal translation of the driver with respect to the drive assembly. The needle assembly is disposed in mechanical cooperation with the driver. Distal translation of the driver causes a corresponding distal translation of the needle assembly. The follower is configured to engage the first helical groove of the drive assembly. When the follower is engaged with the first helical groove, rotation of the drive assembly in the first direction causes distal translation of the follower with respect to the drive assembly.

Abstract: Systems and methods for marking the location and extent of an anatomical region-of-interest, such as a tumor, using magnetic seeds whose position and orientation are measured or otherwise detected using a detection device that includes two or more magnetic sensors are described. One or more magnetic seeds are implanted to mark and define the center and extent of an anatomical region-of-interest and a magnetic sensor-based detector system is used to accurately identify the location of the magnetic seeds.

Abstract: An apparatus for penetrating bone and accessing bone marrow is provided. The apparatus may include a penetrator assembly and a powered drill. The penetrator assembly may include an inner penetrator having a stylet. The penetrator assembly may also include an outer penetrator having a hollow cannula and a luer lock attachment. The powered drill may include a housing enclosing a motor and a power supply and associated circuitry. The powered drill may also include a connector receptacle for receiving a penetrator assembly connector of the penetrator assembly. The powered drill may include a magnetic connection which releasably locks the penetrator assembly connector into place with the powered drill. The power supply may include a rechargeable battery within the housing for supplying power to the motor. A battery indicator may be provided to indicate a level of the battery.

Abstract: A polyp removal device includes an outer tubular body; an inner tubular body; a tubular cutter coupled to or formed as part of the distal end of the inner tubular body; a spring positioned to bias the inner tubular body in an extended direction with respect to the outer tubular body; a handle coupled to the proximal end of the outer tubular body; an actuation member movably coupled to the handle; and a disconnect mechanism for selectively coupling the actuation member to the inner tubular body and decoupling the actuation member from the inner tubular body, the disconnect mechanism is configured to automatically decouple the inner tubular body from the actuation member when the actuation member is moved in a first direction for a distance greater than a predetermined distance.

Abstract: A steerable biopsy device comprises an outer sheath comprising a sheath body having a proximal sheath section and a distal sheath section. The outer sheath further comprises a distal sheath tip and a sheath lumen terminating at a distal port in the distal sheath tip. The biopsy device further comprises a biopsy needle integrated with the sheath body. The biopsy needle is slidably disposed in the sheath lumen. The biopsy needle comprises a needle shaft and a distal needle tip configured for being displaced between a stored position within the sheath lumen and a deployed position outside of the distal port of the distal sheath tip. The biopsy device further comprises an articulation control actuator configured for articulating the distal sheath section, and a needle actuator configured for distally advancing the distal needle tip from the stored position to the deployed position.

Abstract: A surgical end effector includes a clevis and two jaws rotatably coupled to the clevis. A rocking pin in the form of a solid of revolution is pivotally supported by the clevis. The rocking pin may be pivotally supported by the clevis at the midpoint between the first and second ends. The opposite ends of the rocking pin engage the jaws to constrain the jaws to have opposite motions around the axes of rotation of the jaws. The clevis may be coupled to an elongate shaft to provide an endoscopic instrument. The first and second jaws may be electrically isolated from one another for electrocautery and the rocking pin may be formed from a non-conductive material or electrically isolated from the first and second jaws by electrically non-conductive liners. The jaws may be opened and closed by pushing and pulling on wires coupled to the jaws.

Abstract: A universal, self-contained, self-powered, compact, external vacuum source and cytology or cytology and histology collection, storage, preservation and transport system device may be configured to couple to any suitable generic biopsy or interventional device. Embodiments may comprise structures and functionality for the addition of such a portable, compact, self-contained, self-powered, universal vacuum and cytology/histology collection module to biopsy or interventional devices. Embodiments may be portable, disposable or reusable and may be electrically, mechanically and/or manually powered and operated. Embodiments may additionally provide structures and functionality for use with other vacuum and/or cytology or histology collection systems to which this system may itself be attached.

Abstract: A method for using a biopsy device includes providing a housing containing a tension slide, wherein the tension slide is movable to a cocked position against the action of a spring by the power source; inserting a removable element into the housing, the removable element including a biopsy cannula unit, a pressure generating device, a first connection element connecting the biopsy cannula unit and the valve, and a second connection element connecting the valve and the pressure generating device; arranging the biopsy cannula unit on the tension slide; operating the pressure generating device to generate a vacuum; and operating the valve to control pressure buildup and release within the pressure generating device.

Abstract: A surgical system includes a stylus having a proximal end portion and distal end portion configured to penetrate lung tissue. The stylus may be movable between a first configuration and a second configuration within lung tissue. The surgical system may include a surgical instrument configured to treat lung tissue, a sealant configured to seal lung tissue, and an introducer configured for insertion into lung tissue. The introducer may have a proximal end portion and a distal end portion and may define a lumen therethrough configured to separately receive the stylus, the surgical instrument, and the sealant.

Abstract: A biopsy tool includes an elongated flexible body, a sensor assembly, and a screw member. The sensor assembly is disposed within the elongated flexible body towards the distal end thereof. The sensor assembly includes a location sensor(s) configured to enable detection of a location of the sensor assembly. The screw member is coupled to the distal end of elongated flexible body, extends distally from the elongated flexible body, and is positioned distally of the sensor assembly. The screw member defines a helical configuration having a hollow interior and is configured for simultaneous rotation relative to tissue and advancement into tissue to obtain a tissue sample.

Abstract: A housing for use in connection with an inflation device can be coupled to a syringe body by a snap-fit connection. The snap-fit type mechanism can include an adaptor and a lock, such as a depressible lock. The housing can enclose an electrical circuit and a display screen that rests on a plurality of resilient pins. The circuit board may be held in place within the housing via one or more heat pins. The inflation device can be configured to measure pressure within a fluid reservoir of a syringe.

Abstract: An apparatus for penetrating bone and accessing bone marrow is provided. The apparatus may include a penetrator assembly and a powered drill. The penetrator assembly may include an inner penetrator having a stylet. The penetrator assembly may also include an outer penetrator having a hollow cannula and a luer lock attachment. The powered drill may include a housing enclosing a motor and a power supply and associated circuitry. The powered drill may also include a connector receptacle for receiving a penetrator assembly connector of the penetrator assembly. The powered drill may include a magnetic connection which releasably locks the penetrator assembly connector into place with the powered drill. The power supply may include a rechargeable battery within the housing for supplying power to the motor. A battery indicator may be provided to indicate a level of the battery.

Abstract: A cochlear implant insertion-assisting device includes a tubular member configured to hold a cochlear implant. The tubular member includes a cut extending in a longitudinal direction. The cochlear implant insertion-assisting device can selectively switch between a first state in which the cochlear implant is held and a second state in which the cochlear implant can be released.

Abstract: The present invention provides a lifting member which easily inserts a medical thread into a muscle and induces the generation of an autogenous material. For example, the lifting member according to the present invention comprises: a needle having a through hole which is formed therein along the longitudinal direction; and a medical thread coupled to the outer circumference of the needle, wherein the medical thread may be finished to enwrap the end of the needle.

Abstract: A needle system a handle and a needle slider partially positioned in the handle. The needle slider has an aspiration port at a proximal end of the needle slider. A needle connected to and extending away from the needle slider. A restrictor is disposed in the aspiration port of the needle slider. The restrictor is configured to inhibit passage of a sample through the aspiration port.

Abstract: A bone marrow aspiration device and related method includes an introducer assembly and an aspiration assembly to couple to the introducer assembly. The introducer assembly includes an introducer cannula having a proximal end and a distal end. The introducer cannula defines a lumen between the distal and proximal ends, the distal end being configured to penetrate bone of a patient. The aspiration assembly includes an aspiration cannula that is receivable in the lumen of the introducer cannula and that extends beyond the distal end of the introducer cannula. The aspiration cannula includes a port to aspirate bone marrow, the port being distal to the distal end of the introducer cannula. The aspiration device further includes a mechanism at the introducer assembly to move the introducer cannula and the aspiration cannula in tandem relative to a distal end of the mechanism when the aspiration cannula is positioned within bone.

Abstract: A bone marrow aspiration device and related method includes an introducer assembly and an aspiration assembly to couple to the introducer assembly. The introducer assembly includes an introducer cannula having a proximal end and a distal end. The introducer cannula defines a lumen between the distal and proximal ends, the distal end being configured to penetrate bone of a patient. The aspiration assembly includes an aspiration cannula that is receivable in the lumen of the introducer cannula and that extends beyond the distal end of the introducer cannula. The aspiration cannula includes a port to aspirate bone marrow, the port being distal to the distal end of the introducer cannula. The aspiration device further includes a mechanism at the introducer assembly to move the introducer cannula and the aspiration cannula in tandem relative to a distal end of the mechanism when the aspiration cannula is positioned within bone.

Abstract: Devices and methods are provided for automatic vascular access. An automatic vessel cannulation device, mechanical or electronic, has a sensor configured to detect a physiologic parameter of a needle tip, and a blunting device advancing member released in response to the sensor. The sensor may measure pressure or any other physiological parameter. A processor is configured to analyze data sent by the sensor and is pre-set to identify parameters unique to arteries, veins, or other body cavities or organs. A method may include comparing a physiologic parameter with pre-determined parameters to deploy a blunting element if the physiologic parameter is within a range of the pre-determined parameters. An expandable sheath may be included. A device can be provided having a motor controlling the cannulation device orientation to scan tissue with the tip of the needle by moving the cannulation device through the ultrasound transducer.

Abstract: An apparatus for penetrating bone and accessing bone marrow is provided. The apparatus may include a penetrator assembly and a powered drill. The penetrator assembly may include a trocar having a stylet. The penetrator assembly may also include an outer penetrator having a hollow cannula and a luer lock attachment. The powered drill may include a housing enclosing a motor and a power supply and associated circuitry. The powered drill may also include a connector receptacle for receiving a penetrator assembly connector of the penetrator assembly. The connector receptacle may releasably lock the penetrator assembly connector into place with the powered drill. The power supply may include a rechargeable battery within the housing for supplying power to the motor. A battery indicator may be provided to indicate a level of the battery.

Abstract: A system and method for enhancing diagnosis and treatment including an extended working channel defining an elongated passageway and adapted to extend through the bronchoscope and into a luminal network, an opening operably associated with the extended working channel and in fluid communication with the luminal network, and a medical instrument configured for insertion through the extended working channel, wherein during operation, apposition of tissue on the extended working channel or medical instrument isolates at least a portion of a luminal network in which the extended working channel is inserted.

Abstract: A tissue collector includes: an elongated sheath; a bag; a wire bending portion; and an extending portion which is arranged at the distal end portion of the sheath so as to protrude forward from the distal end portion along the longitudinal axis and enter an inside of the bag. The extending portion intersects with the opening surface that is defined by an opening end of the opening portion. The extending portion is configured to be capable of extending inside the bag from an opening surface toward the bottom portion.

Abstract: Implant tools and techniques for implanting implantable medical leads or other implantable components in extracardiovascular locations, such as substernal locations, are described. In one example, the present application provides an implant tool for implanting a medical lead comprises a handle and a shaft. The shaft includes a proximal segment that is permanently coupled to the handle and a distal segment that is detachably coupled to the proximal segment. The distal segment includes a proximal end configured to couple to the proximal segment, a distal end, and a lumen extending an entire length of the distal segment from the proximal end to the distal end. In some instances, the implant tool may be part of a delivery system that includes a puncturing tool having a proximal end and a distal end, wherein the distal end is sharp, such as a syringe coupled to a needle.

Abstract: A tissue removal device includes a housing, an outer tube having a distal portion configured for transcervical insertion into a uterus, an inner tube slidably disposed within the outer tube lumen, a vacuum generation chamber disposed within the housing, a movable piston slidably disposed in the vacuum generation chamber, a collection chamber, a manual actuator moveably coupled to the housing and operatively coupled to the piston, and proximal and distal one-way valves. The outer tube has an outer tube lumen, a tissue in-take opening proximate a distal end thereof, and a proximal end coupled to the housing. The inner tube has an inner tube lumen extending from an open inner tube distal end to an open inner tube proximal end, the open inner tube distal end comprising a cutting edge configured to sever intrauterine tissue extending through the tissue in-take opening in the outer tube.

Abstract: Systems and methods for separating an object such as a pacing lead from a patient tissue involve a flexible and torqueable shaft having an internal lumen sized to receive the object, and a hard separating mechanism for separating the object from the tissue. Typically the shaft and separating mechanism are advanced along or toward the object, and the separating mechanism is contacted with the tissue. The shaft is rotated to effect separation between the object and the tissue. The systems and methods are well suited for use in cardiac pacing or defibrillator lead explant procedures.

Abstract: Devices, systems, and associated methods for selectively extracting a material from a sample are provided. In one aspect, for example, a method for selectively extracting biological material from a biological sample can include identifying a region of biological material to be extracted from a biological sample disposed on a substantially planar surface, applying an extraction tool to the region of biological material to disrupt biological material from the biological sample, and dispensing a liquid at the region of biological material. The method can also include aspirating the liquid and the disrupted biological material from the biological sample.

Abstract: A foreign object removal device is disclosed, which includes a protective sheath, and a device main body, which is disposed in a lumen of the protective sheath, can protrude from a distal end opening of the protective sheath communicating with the lumen and is rotatable relative to the protective sheath. The device main body includes, at a distal end portion protruding from the distal end opening, a screw which rotates integrally with the device main body and in which a flat plate is twisted, and side edges of the flat plate are formed in a spiral shape.

Abstract: A tissue punch including a barrel defining a first open end, a second open end, and inner diameter, an outer diameter, and a lumen there through. A piston is at least partially disposed within the lumen and pressed against the inner diameter of the barrel, the piston being configured to create negative pressure within the barrel when the piston is retracted. A cutting element defines a proximal end and a distal end, the proximal end of the cutting element being disposed at the second open end of the barrel, the distal end of the cutting element defining a cutting edge, the cutting element is in fluid communication with the barrel. A pushing element is slideably disposed about the outer diameter of the barrel, the pushing element is movable from a biased first position away from the cutting edge to a second position proximate the cutting edge.