Delivering Fluid Or Material Through Wall Of Inflated Means Patents (Class 604/103.01)
  • Patent number: 11318204
    Abstract: The present invention relates to a pharmaceutical composition for intravascular delivery of a therapeutic agent, such as paclitaxel, rapamycin, or an analog thereof. The composition includes the therapeutic agent and a biocompatible solvent, such as glycofurol. The composition can aid tissue penetration by the therapeutic agent. A catheter assembly that protects the pharmaceutical composition from the surroundings can be used for its intravascular delivery.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: May 3, 2022
    Assignee: Surmodics, Inc.
    Inventor: Ralph A. Chappa
  • Patent number: 11298218
    Abstract: Various aspects of the present disclosure are directed toward an embolic filter system. The embolic filter system generally includes a filter and an elongated element. In some examples, the elongate element extends to a position distal to a proximal end of the filter and operates to protect against medical devices entangling with the filter. In some examples, the elongate element is soft and compliant and operates with a hemostatic seal to provide for a hemostatic seal within a lumen of the elongate element while maintaining the lumen as a working lumen through which medical devices can be passed.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: April 12, 2022
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: William D. Montgomery, Edward E. Shaw
  • Patent number: 11235128
    Abstract: A method for treating back pain in a patient in need of such treatment is provided. The method includes positioning a balloon catheter in or adjacent to a treatment zone containing a basivertebral nerve. A chemical denervation agent is administered with the balloon catheter such that the chemical denervation agent chemically ablates at least a portion of the basivertebral nerve. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: February 1, 2022
    Assignee: MEDTRONIC HOLDING COMPANY SÀRL
    Inventor: Mojan Goshayeshgar
  • Patent number: 11213320
    Abstract: A uterine manipulator includes a handle and a central shaft that extends distally from the handle. The central shaft includes a distal end portion supporting a balloon. The central shaft also supports a cervical cup. An occluder shaft is slidably supported on the central shaft. A non-inflatable plug is secured to the occluder shaft and configured to move with the occluder shaft as the occluder shaft slides along the central shaft.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: January 4, 2022
    Assignee: COVIDIEN LP
    Inventors: Scott J. Prior, Danial P. Ferreira, Paul C. DiCesare
  • Patent number: 11207272
    Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject).
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: December 28, 2021
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Carlo Giovanni Traverso, Alex G. Abramson, Ester Caffarel Salvador, Niclas Roxhed, Minsoo Khang, Taylor Bensel, David Dellal, Robert S. Langer
  • Patent number: 11185332
    Abstract: Catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially in the reduction of contrast-induced acute kidney injury. The catheter devices, systems and associated methods may prevent contrast dyes from entering into the kidney and/or facilitate blood flow beyond the kidney by utilization of the catheter devices, systems and associated methods.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 30, 2021
    Assignee: RenalPro Medical, Inc.
    Inventor: Eran Levit
  • Patent number: 11129960
    Abstract: An embolization microcatheter having an elongated microcatheter body configured for passing therein a suspension of particles suspended in a suspension fluid; and a microcatheter head connected to a distal end of said microcatheter body and comprising a proximal head section and a distal head section, wherein the proximal head section includes a proximal wall forming a proximal section lumen, the proximal wall having a plurality of through-holes, wherein the distal head section includes a distal wall forming a distal section lumen, and a suspension delivery opening at a distal end of the distal end section; wherein the distal section is devoid of through-holes, and wherein each of the plurality of through-holes are shaped and/or sized to allow passage therethrough of the suspension fluid while blocking passage of the particles suspended therein.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: September 28, 2021
    Assignee: ACCURATE MEDICAL THERAPEUTICS LTD.
    Inventors: Michael Gabriel Tal, Eran Miller
  • Patent number: 11129926
    Abstract: The present disclosure provides for a medical device or a substrate coated with polydopamine which is further linked to ligands such as antibodies and/or antibody fragments. The polydopamine coating and the ligands may be linked through a linker such as an organic polymer.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: September 28, 2021
    Assignee: OrbusNeich Medical PTE. LTD.
    Inventor: Michael J. B. Kutryk
  • Patent number: 11077287
    Abstract: A non-occluding drug-coated balloon catheter device for use in a blood vessel transporting blood comprises a catheter shaft including a guidewire lumen, a fluid lumen and a connector port. A balloon is mounted on the catheter shaft and includes an outer envelope surrounding the guidewire lumen in fluid communication with the fluid lumen; a drug coating applied on the exterior surface of the outer envelope; and at least one bypass lumen forming a passage extending from the proximal end of the outer envelope to the distal end of the outer envelope. When the balloon is positioned in a blood vessel and inflated, the exterior surface of the outer envelope presses the drug coating against the blood vessel and the bypass lumen is open between the distal end of the outer envelope and the proximal end of the outer envelope such that blood transport continues through the bypass lumen.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: August 3, 2021
    Assignee: ANLVR, LLC
    Inventors: Vijay Sitharam Ramanath, Brett Allyn Williams
  • Patent number: 11071534
    Abstract: A system for endoscopic surgery within a body lumen of a patient including a flexible catheter having an expandable region at a distal portion and an access opening. The expandable region is expandable from a collapsed insertion configuration to an expanded configuration to provide an expanded chamber on a first side of the catheter. The access opening is positioned on a second side opposite the first side to provide a window to access target tissue. The catheter includes a lumen dimensioned to receive an endoscopic instrument therethrough such that a distal end of the endoscopic instrument is positionable within the expanded chamber and angled laterally within the expanded chamber to access the target tissue through the window.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: July 27, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventor: Gregory Piskun
  • Patent number: 11065007
    Abstract: A vascular plug comprises a superstructure expandable from a collapsed percutaneous insertion configuration to an expanded deployment or use configuration. The superstructure incorporates a channel or passageway and a catheter extends through the channel or passageway from a proximal side at least to a distal side of the superstructure. The central channel allows for over-the wire plug delivery and a working aperture for secondary vascular interventions under flow arrest prior to final plug release. The plug includes spring-loaded mechanical elements or clotting-enhancement structure for closing the channel or passageway upon a withdrawal or removal of the catheter from the superstructure.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: July 20, 2021
    Inventor: John S. DeMeritt
  • Patent number: 11007346
    Abstract: At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium, or the aortic wall.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: May 18, 2021
    Assignee: Ablative Solutions, Inc.
    Inventors: David R. Fischell, Tim A. Fischell
  • Patent number: 10953170
    Abstract: Apparatus and methods for providing intrabronchial delivery of a treatment fluid to control the effects of a bronchial condition. The apparatus can include a shaft having proximal and distal ends and a fluid injection assembly disposed on the distal end. The fluid injection assembly can be a deployable needle assembly, a rotating needle assembly, a needle-less injection assembly, or a nebulizer assembly.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: March 23, 2021
    Assignee: Nuvaira, Inc.
    Inventors: Mark E. Deem, Hanson S. Gifford, III
  • Patent number: 10945739
    Abstract: The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a resident substance from the organic cavity and simultaneously prevent removal of the non-activated photo-activatable substance from the organic cavity; and an optical waveguide for providing electromagnetic radiation inside the organic cavity to the photo-activatable substance to photoactive the photo-activatable substance inside the organic cavity.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: March 16, 2021
    Assignee: Ecole Polytechnique Federale de Lausanne (EPEL)
    Inventors: Andreas Schmocker, Christophe Moser, Pascal Mosimann
  • Patent number: 10926064
    Abstract: Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: February 23, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Jeffrey B. Duncan, Douglas S. Paget, Rachel Radspinner, Edward E. Shaw, Michael J. Vonesh
  • Patent number: 10918510
    Abstract: A medical device includes a vessel member, a port that couples a compartment interior of the vessel member to a region exterior of the vessel member, and a tubular member that defines a lumen. A distal end of the tubular member is attached to an internal surface of the vessel member within the compartment so that a portion of the internal surface of the vessel member provides a seal at a distal end of the lumen. The tubular member passes through the port, and the proximal end of the tubular member is configured to remain exterior of the compartment. A delivery of a sufficient amount of a filling material into the lumen of the tubular member causes a length of the tubular member to pass through the port and into the vessel compartment.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: February 16, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Michael J. Vonesh
  • Patent number: 10898213
    Abstract: The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using electrically-induced pressure waves created within a sheath to disrupt vascular blockages via the sheath and/or a tip at the end of the sheath.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: January 26, 2021
    Assignee: THE SPECTRANETICS CORPORATION
    Inventors: Kenneth P. Grace, Thomas Triffo, James Cezo
  • Patent number: 10850078
    Abstract: The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages. The present disclosure not only provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages, but the present disclosure also provides devices and method for assisting the guidewire in penetrating an occlusion, devices and method for using a sealable valve in the tip of the balloon catheter to reduce the overall size and diameter of the balloon catheter, thereby allowing the balloon catheter to penetrate smaller size blood vessels and devices. Given the persistence of coronary artery disease (CAD) and peripheral artery disease (PAD), there remains a need for improved therapeutic methods designed not only to reduce vascular blockages in the short term, but also to prevent future complications such as restenosis.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: December 1, 2020
    Assignee: THE SPECTRANETICS CORPORATION
    Inventors: Kenneth P. Grace, Thomas Triffo, James Cezo
  • Patent number: 10799269
    Abstract: A sterile liquid transfer assembly for use with a catheter assembly. The sterile liquid transfer assembly includes a protective element and a carrier element. The protective element includes a pliable, hollow protective valve member having a pivot cutaway portion. A tubular member of the protective element depends from a surface of the hollow protective valve member. The protective valve member is configured to define a stop for limiting the insertion of the tubular member in a canal of a patient.
    Type: Grant
    Filed: September 16, 2018
    Date of Patent: October 13, 2020
    Inventor: Carlos Navarro Alvarez
  • Patent number: 10709500
    Abstract: An irrigated ablation catheter includes a shaft having a proximal end, a distal end, and an irrigation lumen therein. The catheter further includes an electrode assembly coupled to the distal end of the shaft. The electrode assembly includes an ablation electrode and a manifold. The manifold is coupled to each of the distal end of the shaft and the proximal end of the electrode. At least a portion of the manifold is constructed of a flexible material to allow the electrode assembly to deflect. The manifold includes a body, an inner cavity within the body configured for fluid communication with the irrigation lumen, and an irrigation port also within the body and configured for fluid communication with the inner cavity. The irrigation port extends from the inner cavity to the outer surface of the body, and is configured to allow for an irrigating fluid to be distributed from the manifold.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: July 14, 2020
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventor: Huisun Wang
  • Patent number: 10653481
    Abstract: An irrigated ablation catheter includes a shaft and an electrode assembly affixed to a distal end of the shaft. The distal electrode assembly includes a manifold and an ablation electrode affixed together and extending along a center axis. The electrode has a distal irrigation passageway extending therethrough to an opening at a distal tip of the electrode. The opening of the irrigation passageway is offset in distance from the center axis, and allows a thermal sensor such as a thermocouple to be located in a sensor cavity in the electrode on or near the center axis. One variation involves providing a pair of distal irrigation passageways through the electrode where both of the openings of the passageways are offset from the center axis. The thermal sensor in this variation is located in the sensor cavity substantially on the center axis.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: May 19, 2020
    Assignee: St. Jude Medical, Atrial Fibrillation Divison, Inc.
    Inventors: Huisun Wang, Christopher J. Geurkink
  • Patent number: 10617443
    Abstract: A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is monolithically connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements. The dilation element has a flattened outer surface along at least proximal and distal neck portions of the balloon.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 14, 2020
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: David G. Burton, Darin G. Schaeffer, David A. Drewes
  • Patent number: 10470924
    Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: November 12, 2019
    Assignee: The Johns Hopkins University
    Inventors: Signe Erickson, Eugene de Juan, Jr., Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. Cooney
  • Patent number: 10441758
    Abstract: Substance delivering spacer devices may comprise expandable reservoirs that are implantable in paranasal sinuses and other cavities, openings and passageways of the body to maintain patency and to provide sustained local delivery of a therapeutic or diagnostic substance. Delivery apparatus including elongate tubular members as well as shapeable distal portions and atraumatic tips are provided. Also provided are sinus penetrator devices and systems for performing ethmoidotomy procedures or for creating other openings in the walls of paranasal sinuses or other anatomical structures.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: October 15, 2019
    Assignee: Acclarent, Inc.
    Inventors: Ketan P. Muni, Hung V. Ha, Randy S. Chan, Nga K. Van
  • Patent number: 10398441
    Abstract: An occlusive system for the vasculature and an embolic coil used in such an occlusive system is described. Also described is an occlusive plug which can be used for occlusive purposes within the vasculature.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: September 3, 2019
    Assignee: Terumo Corporation
    Inventors: Sheila Warner, Jacqueline Macias, Jessica Liang, Wendy Graczyk
  • Patent number: 10335224
    Abstract: An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 2, 2019
    Assignee: AngioDynamics, Inc.
    Inventors: Victor Chornenky, Ali Jaafar
  • Patent number: 10328290
    Abstract: Systems and methods for treating a blood clot positioned within a blood vessel are disclosed. In one embodiment, a balloon member is positioned on a distal end region of a catheter and an ultrasound emitting element is positioned within the balloon member and arranged for actively emitting ultrasound. In some exemplary embodiments, the disclosure provides a multi-wall balloon member and a multi-lumen catheter with at least one and/or all cavities of the balloon member arranged for heat transfer with the ultrasound emitting element. The disclosure also provides catheter arrangements with an ultrasound emitting element arranged to heat tissue adjacent to the balloon member. Additionally, in some embodiments, at least one and/or all walls of the balloon member have apertures arranged to release a therapeutic agent such as a thrombolytic drug.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: June 25, 2019
    Assignee: Muffin Incorporated
    Inventors: Yun Zhou, Peter S. McKinnis, Sarah Robbins, Neal E. Fearnot
  • Patent number: 10321946
    Abstract: The disclosure pertains to an intravascular catheter, comprising an elongate member having a proximal end and a distal end, a balloon having an interior surface, an exterior surface, a lumen defined by the interior surface and a cylindrical wall extending between the interior surface and the exterior surface, the cylindrical wall having a proximal end and a distal end, the balloon having a plurality of weeping windows disposed in the wall and able to pass an electric current between the interior surface and the exterior surface and wherein the balloon wall is otherwise electrically insulative, and an electrode disposed in the balloon. The intravascular system is suited for modulation of renal nerves, for example.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: June 18, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Daniel J. Horn, Cass A. Hanson, Derek C. Sutermeister, Timothy A. Ostroot, Daniel T. Quillin
  • Patent number: 10293144
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: May 21, 2019
    Assignee: Sentinent Holdings, LLC
    Inventor: Alvaro J. Laguna
  • Patent number: 10286191
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue, In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 14, 2019
    Assignee: Neurotronic, Inc.
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • Patent number: 10286115
    Abstract: An expandable medical balloon including an inner layer formed of a poly (ether-block-amide) copolymer and an outer layer formed of a polyamide, the expandable medical balloon having a burst strength of greater than 50,000 psi, and to methods of making and using the same.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: May 14, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John J. Chen, Daniel J. Horn
  • Patent number: 10272192
    Abstract: A drug delivery device is provided for directly treating a treatment site. The device allows body fluids to perfuse past the device while it is expanded to increase the amount of treatment time that is possible. The drug is delivered through a hollow helical tube that extends around a support structure. The hollow tube includes a series of lateral holes to allow the drug to directly reach the desired treatment site.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: April 30, 2019
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Keith R. Milner, Triona Campbell, Jr.
  • Patent number: 10219855
    Abstract: Systems, devices, and methods for treating a patient having a sympathetically mediated disease associated at least in part with augmented peripheral chemoreflex or heightened sympathetic activation. The treatments include ablating one or more peripheral chemoreceptors or associated afferent nerves to reduce or remove afferent neural signals from the peripheral chemoreceptor.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: March 5, 2019
    Assignee: Cibiem, Inc.
    Inventors: Mark Gelfand, Howard Levin
  • Patent number: 10201421
    Abstract: A delivery system for delivering and deploying a medical implant, such as a prosthetic heart valve, includes an elongated support member, a sheath, and a tip. The sheath is movable relative to the elongated support member between a distal position overlying the medical implant and a proximal position exposing the medical implant for release from the delivery system. The tip is attached to the elongated support member and is positioned at a distal end of the sheath when the sheath is in the distal position. The tip has a compressed condition and an expanded condition, and a maximum diameter in the expanded condition that is larger than the outer diameter of the sheath.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: February 12, 2019
    Assignee: St. Jude Medical, LLC
    Inventors: Huisun Wang, Valerie J. Glazier
  • Patent number: 10182864
    Abstract: An irrigated ablation catheter includes a shaft having a proximal end, a distal end, and an irrigation lumen therein. The catheter further includes an electrode assembly coupled to the distal end of the shaft. The electrode assembly includes an ablation electrode and a manifold. The manifold is coupled to each of the distal end of the shaft and the proximal end of the electrode. At least a portion of the manifold is constructed of a flexible material to allow the electrode assembly to deflect. The manifold includes a body, an inner cavity within the body configured for fluid communication with the irrigation lumen, and an irrigation port also within the body and configured for fluid communication with the inner cavity. The irrigation port extends from the inner cavity to the outer surface of the body, and is configured to allow for an irrigating fluid to be distributed from the manifold.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: January 22, 2019
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventor: Huisun Wang
  • Patent number: 10112034
    Abstract: A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: October 30, 2018
    Assignee: J.W. Medical Systems Ltd.
    Inventors: David W. Snow, Patrick H. Ruane
  • Patent number: 10076642
    Abstract: The present disclosure is directed toward a semi-compliant to non-compliant, conformable balloon useful in medical applications. Conformable balloons of the present disclosure exhibit a low or insignificant straightening force when in a curved configuration and at inflation pressures greater than 4 atm. Balloons of the present disclosure are constructed of material that can compress along an inner length when the balloon is in a curved configuration. In further embodiments, balloons of the present disclosure can be constructed of material that sufficiently elongates along an outer arc when the balloon is in a curved configuration. As a result, medical balloons, in accordance with the present disclosure, when inflated in a curved configuration, exhibit kink-free configurations and do not cause a significant degree of vessel straightening.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: September 18, 2018
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Carey V. Campbell, Matthew E. Maulding, Benjamin M. Trapp
  • Patent number: 10029069
    Abstract: Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: July 24, 2018
    Assignee: ENTELLUS MEDICAL, INC.
    Inventors: Peter T. Keith, Reuben C. Setliff, III
  • Patent number: 10016212
    Abstract: A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: July 10, 2018
    Assignee: Cook Medical Technologies LLC
    Inventors: David G. Burton, Darin G. Schaeffer, David A. Drewes
  • Patent number: 9956384
    Abstract: Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: May 1, 2018
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Steven Charlebois, Sara Sherman
  • Patent number: 9943396
    Abstract: Various devices are described to provide filtering of flow from the aorta to the left carotid artery and the right carotid artery. The filters can be brought into a desired position through one or more peripheral arteries. A single filter device can provide the desired filtering or a plurality of devices can be used. In particular a single filter device can span between the brachiocephalic artery and the left carotid artery. These filter devices can be used effectively to capture emboli generated during procedures on the heart so that emboli do not travel to the patient's brain where the emboli can cause a stroke or other adverse event. In particular, these filters can be used during percutaneous procedures on the heart, such as endovascular heart valve replacement.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: April 17, 2018
    Assignee: Lumen Biomedical, Inc.
    Inventors: Jason A. Galdonik, Matthew F. Ogle, Edward Anderson, Mark W. I. Webster
  • Patent number: 9839523
    Abstract: A spacer for a knee replacement prosthesis. The spacer may have a lower surface with a locking component adapted to interlock with a tibial tray, an upper surface optionally with a tibial post and a pair of smooth-surfaced and slightly concave condyle support platforms disposed on opposite sides of the tibial post, and a substantially hollow body with an internal reservoir that can be filled with antibiotic material. The reservoir may be accessible from a port on the hollow body that leads into the internal reservoir, and which permits refilling of the reservoir. In some embodiments, the reservoir may be refillable from this port without removal of the spacer from the patient; for example, a percutaneous needle may be inserted into the port. The spacer may dispense antibiotic from this reservoir to the surrounding area in order to treat an infection.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: December 12, 2017
    Inventor: Jared Ruben Hillel Foran
  • Patent number: 9833547
    Abstract: The invention relates to a drug-coated balloon catheter and to a method for producing the same. The balloon of the catheter includes (i) a main membrane, and (ii) an asymmetrical polymer membrane which is applied to an outside of the main membrane and into which at least one pharmaceutical active ingredient is introduced.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: December 5, 2017
    Assignee: Biotronik VI Patent AG
    Inventors: Michael Tittelbach, Raimund Moehl, Alwin Schwitzer, Matthias Wesselmann, Bodo Quint, Patrice Bachmann
  • Patent number: 9744039
    Abstract: A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: August 29, 2017
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Arshad Quadri, J. Brent Ratz
  • Patent number: 9724192
    Abstract: Apparatus for percutaneous access to a patient's body comprising a first steerable tube (12), shaped to define a first lumen, and a first coupling (152) at a longitudinal site of the first tube; and a second steerable tube (14), shaped to define a second lumen and a second coupling (154), the second coupling being intracorporeally couplable to the first coupling, the apparatus having (A) an unlocked state in which the second tube is rotatable within the first lumen, and (B) a locked state in which the second coupling is coupled to the first coupling, and rotation of the second tube is inhibited. The apparatus is configured such that when the second coupling becomes disposed at the longitudinal site in a given rotational orientation of the second tube, the apparatus moves into the locked state by the second coupling automatically coupling to the first coupling. Other embodiments are also described.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: August 8, 2017
    Assignee: Valtech Cardio, Ltd.
    Inventors: Tal Sheps, Tal Hammer, Ehud Iflah, Tal Reich, Yaron Herman, Amir Gross
  • Patent number: 9526874
    Abstract: Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: December 27, 2016
    Assignee: ADVANCED CATHETER THERAPIES, INC.
    Inventors: C. Rex Teeslink, Dirk V. Hoyns
  • Patent number: 9526506
    Abstract: A device for treating the lumen of a living body includes a shaft insertable into a blood vessel, and a balloon provided on the shaft and shiftable between a deflated state and an expanded state. In the expanded state, the balloon has a recessed portion configured to form a coating chamber which is substantially blocked between an inner surface of the blood vessels and the device for treating the lumen of a living body, a discharge port provided on the recessed portion to discharge a coating substance toward the coating chamber; and a suction port provided on the recessed portion to apply a negative pressure to the coating chamber.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: December 27, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hideaki Shibata, Naoki Ishii, Satoshi Sawada
  • Patent number: 9409000
    Abstract: The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a balloon having an inner and outer surface defining a wall, and an interior volume with an unexpanded and expanded configuration and a plurality of fibers extending from the outer surface of the balloon wall. In another exemplary embodiment, a balloon catheter comprises a catheter having a balloon with an unexpanded and an expanded configuration, and a retractable sheath disposed on the exterior surface of the balloon, wherein the sheath has an inner surface and an outer surface, and further wherein a plurality of fibers outwardly extend from the outer surface of the sheath.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: August 9, 2016
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Barbara E. Stamberg
  • Patent number: 9370642
    Abstract: A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: June 21, 2016
    Assignee: J.W. MEDICAL SYSTEMS LTD.
    Inventors: David W. Snow, Patrick H. Ruane
  • Patent number: 9351736
    Abstract: Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: May 31, 2016
    Assignee: Vascular Solutions, Inc.
    Inventors: Howard Root, James Arnold Murto, Stephen Anthony Penegor, Gregg Sutton