Delivering Fluid Or Material Through Wall Of Inflated Means Patents (Class 604/103.01)
  • Patent number: 10799269
    Abstract: A sterile liquid transfer assembly for use with a catheter assembly. The sterile liquid transfer assembly includes a protective element and a carrier element. The protective element includes a pliable, hollow protective valve member having a pivot cutaway portion. A tubular member of the protective element depends from a surface of the hollow protective valve member. The protective valve member is configured to define a stop for limiting the insertion of the tubular member in a canal of a patient.
    Type: Grant
    Filed: September 16, 2018
    Date of Patent: October 13, 2020
    Inventor: Carlos Navarro Alvarez
  • Patent number: 10709500
    Abstract: An irrigated ablation catheter includes a shaft having a proximal end, a distal end, and an irrigation lumen therein. The catheter further includes an electrode assembly coupled to the distal end of the shaft. The electrode assembly includes an ablation electrode and a manifold. The manifold is coupled to each of the distal end of the shaft and the proximal end of the electrode. At least a portion of the manifold is constructed of a flexible material to allow the electrode assembly to deflect. The manifold includes a body, an inner cavity within the body configured for fluid communication with the irrigation lumen, and an irrigation port also within the body and configured for fluid communication with the inner cavity. The irrigation port extends from the inner cavity to the outer surface of the body, and is configured to allow for an irrigating fluid to be distributed from the manifold.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: July 14, 2020
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventor: Huisun Wang
  • Patent number: 10653481
    Abstract: An irrigated ablation catheter includes a shaft and an electrode assembly affixed to a distal end of the shaft. The distal electrode assembly includes a manifold and an ablation electrode affixed together and extending along a center axis. The electrode has a distal irrigation passageway extending therethrough to an opening at a distal tip of the electrode. The opening of the irrigation passageway is offset in distance from the center axis, and allows a thermal sensor such as a thermocouple to be located in a sensor cavity in the electrode on or near the center axis. One variation involves providing a pair of distal irrigation passageways through the electrode where both of the openings of the passageways are offset from the center axis. The thermal sensor in this variation is located in the sensor cavity substantially on the center axis.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: May 19, 2020
    Assignee: St. Jude Medical, Atrial Fibrillation Divison, Inc.
    Inventors: Huisun Wang, Christopher J. Geurkink
  • Patent number: 10617443
    Abstract: A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is monolithically connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements. The dilation element has a flattened outer surface along at least proximal and distal neck portions of the balloon.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 14, 2020
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: David G. Burton, Darin G. Schaeffer, David A. Drewes
  • Patent number: 10470924
    Abstract: A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: November 12, 2019
    Assignee: The Johns Hopkins University
    Inventors: Signe Erickson, Eugene de Juan, Jr., Aaron Christopher Barnes, Terry Harrison Shelley, Michael J. Cooney
  • Patent number: 10441758
    Abstract: Substance delivering spacer devices may comprise expandable reservoirs that are implantable in paranasal sinuses and other cavities, openings and passageways of the body to maintain patency and to provide sustained local delivery of a therapeutic or diagnostic substance. Delivery apparatus including elongate tubular members as well as shapeable distal portions and atraumatic tips are provided. Also provided are sinus penetrator devices and systems for performing ethmoidotomy procedures or for creating other openings in the walls of paranasal sinuses or other anatomical structures.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: October 15, 2019
    Assignee: Acclarent, Inc.
    Inventors: Ketan P. Muni, Hung V. Ha, Randy S. Chan, Nga K. Van
  • Patent number: 10398441
    Abstract: An occlusive system for the vasculature and an embolic coil used in such an occlusive system is described. Also described is an occlusive plug which can be used for occlusive purposes within the vasculature.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: September 3, 2019
    Assignee: Terumo Corporation
    Inventors: Sheila Warner, Jacqueline Macias, Jessica Liang, Wendy Graczyk
  • Patent number: 10335224
    Abstract: An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 2, 2019
    Assignee: AngioDynamics, Inc.
    Inventors: Victor Chornenky, Ali Jaafar
  • Patent number: 10328290
    Abstract: Systems and methods for treating a blood clot positioned within a blood vessel are disclosed. In one embodiment, a balloon member is positioned on a distal end region of a catheter and an ultrasound emitting element is positioned within the balloon member and arranged for actively emitting ultrasound. In some exemplary embodiments, the disclosure provides a multi-wall balloon member and a multi-lumen catheter with at least one and/or all cavities of the balloon member arranged for heat transfer with the ultrasound emitting element. The disclosure also provides catheter arrangements with an ultrasound emitting element arranged to heat tissue adjacent to the balloon member. Additionally, in some embodiments, at least one and/or all walls of the balloon member have apertures arranged to release a therapeutic agent such as a thrombolytic drug.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: June 25, 2019
    Assignee: Muffin Incorporated
    Inventors: Yun Zhou, Peter S. McKinnis, Sarah Robbins, Neal E. Fearnot
  • Patent number: 10321946
    Abstract: The disclosure pertains to an intravascular catheter, comprising an elongate member having a proximal end and a distal end, a balloon having an interior surface, an exterior surface, a lumen defined by the interior surface and a cylindrical wall extending between the interior surface and the exterior surface, the cylindrical wall having a proximal end and a distal end, the balloon having a plurality of weeping windows disposed in the wall and able to pass an electric current between the interior surface and the exterior surface and wherein the balloon wall is otherwise electrically insulative, and an electrode disposed in the balloon. The intravascular system is suited for modulation of renal nerves, for example.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: June 18, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Daniel J. Horn, Cass A. Hanson, Derek C. Sutermeister, Timothy A. Ostroot, Daniel T. Quillin
  • Patent number: 10293144
    Abstract: Systems and method for using a sleeve for enhanced drug delivery are described. The sleeve may incorporate porous materials and may be coated or treated with various drugs and/or therapeutic agents. The sleeve may be utilized in cooperation with balloon catheters and/or other devices. When acting as a reservoir for holding various drugs and/or therapeutic agents, the drug delivery sleeve provides a means of reducing drug losses as well as a controlled mechanism for drug release. The materials for the sleeve, constructed by various techniques, may be circumferentially distensible, may be elastic, and may have varying degrees of recoil as needed for any particular purpose.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: May 21, 2019
    Assignee: Sentinent Holdings, LLC
    Inventor: Alvaro J. Laguna
  • Patent number: 10286115
    Abstract: An expandable medical balloon including an inner layer formed of a poly (ether-block-amide) copolymer and an outer layer formed of a polyamide, the expandable medical balloon having a burst strength of greater than 50,000 psi, and to methods of making and using the same.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: May 14, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John J. Chen, Daniel J. Horn
  • Patent number: 10286191
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue, In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 14, 2019
    Assignee: Neurotronic, Inc.
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • Patent number: 10272192
    Abstract: A drug delivery device is provided for directly treating a treatment site. The device allows body fluids to perfuse past the device while it is expanded to increase the amount of treatment time that is possible. The drug is delivered through a hollow helical tube that extends around a support structure. The hollow tube includes a series of lateral holes to allow the drug to directly reach the desired treatment site.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: April 30, 2019
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Keith R. Milner, Triona Campbell, Jr.
  • Patent number: 10219855
    Abstract: Systems, devices, and methods for treating a patient having a sympathetically mediated disease associated at least in part with augmented peripheral chemoreflex or heightened sympathetic activation. The treatments include ablating one or more peripheral chemoreceptors or associated afferent nerves to reduce or remove afferent neural signals from the peripheral chemoreceptor.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: March 5, 2019
    Assignee: Cibiem, Inc.
    Inventors: Mark Gelfand, Howard Levin
  • Patent number: 10201421
    Abstract: A delivery system for delivering and deploying a medical implant, such as a prosthetic heart valve, includes an elongated support member, a sheath, and a tip. The sheath is movable relative to the elongated support member between a distal position overlying the medical implant and a proximal position exposing the medical implant for release from the delivery system. The tip is attached to the elongated support member and is positioned at a distal end of the sheath when the sheath is in the distal position. The tip has a compressed condition and an expanded condition, and a maximum diameter in the expanded condition that is larger than the outer diameter of the sheath.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: February 12, 2019
    Assignee: St. Jude Medical, LLC
    Inventors: Huisun Wang, Valerie J. Glazier
  • Patent number: 10182864
    Abstract: An irrigated ablation catheter includes a shaft having a proximal end, a distal end, and an irrigation lumen therein. The catheter further includes an electrode assembly coupled to the distal end of the shaft. The electrode assembly includes an ablation electrode and a manifold. The manifold is coupled to each of the distal end of the shaft and the proximal end of the electrode. At least a portion of the manifold is constructed of a flexible material to allow the electrode assembly to deflect. The manifold includes a body, an inner cavity within the body configured for fluid communication with the irrigation lumen, and an irrigation port also within the body and configured for fluid communication with the inner cavity. The irrigation port extends from the inner cavity to the outer surface of the body, and is configured to allow for an irrigating fluid to be distributed from the manifold.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: January 22, 2019
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventor: Huisun Wang
  • Patent number: 10112034
    Abstract: A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: October 30, 2018
    Assignee: J.W. Medical Systems Ltd.
    Inventors: David W. Snow, Patrick H. Ruane
  • Patent number: 10076642
    Abstract: The present disclosure is directed toward a semi-compliant to non-compliant, conformable balloon useful in medical applications. Conformable balloons of the present disclosure exhibit a low or insignificant straightening force when in a curved configuration and at inflation pressures greater than 4 atm. Balloons of the present disclosure are constructed of material that can compress along an inner length when the balloon is in a curved configuration. In further embodiments, balloons of the present disclosure can be constructed of material that sufficiently elongates along an outer arc when the balloon is in a curved configuration. As a result, medical balloons, in accordance with the present disclosure, when inflated in a curved configuration, exhibit kink-free configurations and do not cause a significant degree of vessel straightening.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: September 18, 2018
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Carey V. Campbell, Matthew E. Maulding, Benjamin M. Trapp
  • Patent number: 10029069
    Abstract: Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: July 24, 2018
    Assignee: ENTELLUS MEDICAL, INC.
    Inventors: Peter T. Keith, Reuben C. Setliff, III
  • Patent number: 10016212
    Abstract: A balloon catheter is provided that may be used to dilate hardened regions of a stenosis. The balloon catheter is provided with one or more dilation elements that extend along a surface of a balloon. Each dilation element is connected to an outer surface of the balloon by a connector. The connector is sufficiently sized and designed to undergo stress-induced plastic deformation incurred during blow molding so that a significant portion of each of the dilation elements does not become absorbed into the wall of the final blow molded balloon, thereby maintaining the structural integrity of each of the dilation elements.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: July 10, 2018
    Assignee: Cook Medical Technologies LLC
    Inventors: David G. Burton, Darin G. Schaeffer, David A. Drewes
  • Patent number: 9956384
    Abstract: Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: May 1, 2018
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Steven Charlebois, Sara Sherman
  • Patent number: 9943396
    Abstract: Various devices are described to provide filtering of flow from the aorta to the left carotid artery and the right carotid artery. The filters can be brought into a desired position through one or more peripheral arteries. A single filter device can provide the desired filtering or a plurality of devices can be used. In particular a single filter device can span between the brachiocephalic artery and the left carotid artery. These filter devices can be used effectively to capture emboli generated during procedures on the heart so that emboli do not travel to the patient's brain where the emboli can cause a stroke or other adverse event. In particular, these filters can be used during percutaneous procedures on the heart, such as endovascular heart valve replacement.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: April 17, 2018
    Assignee: Lumen Biomedical, Inc.
    Inventors: Jason A. Galdonik, Matthew F. Ogle, Edward Anderson, Mark W. I. Webster
  • Patent number: 9839523
    Abstract: A spacer for a knee replacement prosthesis. The spacer may have a lower surface with a locking component adapted to interlock with a tibial tray, an upper surface optionally with a tibial post and a pair of smooth-surfaced and slightly concave condyle support platforms disposed on opposite sides of the tibial post, and a substantially hollow body with an internal reservoir that can be filled with antibiotic material. The reservoir may be accessible from a port on the hollow body that leads into the internal reservoir, and which permits refilling of the reservoir. In some embodiments, the reservoir may be refillable from this port without removal of the spacer from the patient; for example, a percutaneous needle may be inserted into the port. The spacer may dispense antibiotic from this reservoir to the surrounding area in order to treat an infection.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: December 12, 2017
    Inventor: Jared Ruben Hillel Foran
  • Patent number: 9833547
    Abstract: The invention relates to a drug-coated balloon catheter and to a method for producing the same. The balloon of the catheter includes (i) a main membrane, and (ii) an asymmetrical polymer membrane which is applied to an outside of the main membrane and into which at least one pharmaceutical active ingredient is introduced.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: December 5, 2017
    Assignee: Biotronik VI Patent AG
    Inventors: Michael Tittelbach, Raimund Moehl, Alwin Schwitzer, Matthias Wesselmann, Bodo Quint, Patrice Bachmann
  • Patent number: 9744039
    Abstract: A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: August 29, 2017
    Assignee: Edwards Lifesciences CardiAQ LLC
    Inventors: Arshad Quadri, J. Brent Ratz
  • Patent number: 9724192
    Abstract: Apparatus for percutaneous access to a patient's body comprising a first steerable tube (12), shaped to define a first lumen, and a first coupling (152) at a longitudinal site of the first tube; and a second steerable tube (14), shaped to define a second lumen and a second coupling (154), the second coupling being intracorporeally couplable to the first coupling, the apparatus having (A) an unlocked state in which the second tube is rotatable within the first lumen, and (B) a locked state in which the second coupling is coupled to the first coupling, and rotation of the second tube is inhibited. The apparatus is configured such that when the second coupling becomes disposed at the longitudinal site in a given rotational orientation of the second tube, the apparatus moves into the locked state by the second coupling automatically coupling to the first coupling. Other embodiments are also described.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: August 8, 2017
    Assignee: Valtech Cardio, Ltd.
    Inventors: Tal Sheps, Tal Hammer, Ehud Iflah, Tal Reich, Yaron Herman, Amir Gross
  • Patent number: 9526874
    Abstract: Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: December 27, 2016
    Assignee: ADVANCED CATHETER THERAPIES, INC.
    Inventors: C. Rex Teeslink, Dirk V. Hoyns
  • Patent number: 9526506
    Abstract: A device for treating the lumen of a living body includes a shaft insertable into a blood vessel, and a balloon provided on the shaft and shiftable between a deflated state and an expanded state. In the expanded state, the balloon has a recessed portion configured to form a coating chamber which is substantially blocked between an inner surface of the blood vessels and the device for treating the lumen of a living body, a discharge port provided on the recessed portion to discharge a coating substance toward the coating chamber; and a suction port provided on the recessed portion to apply a negative pressure to the coating chamber.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: December 27, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hideaki Shibata, Naoki Ishii, Satoshi Sawada
  • Patent number: 9409000
    Abstract: The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a balloon having an inner and outer surface defining a wall, and an interior volume with an unexpanded and expanded configuration and a plurality of fibers extending from the outer surface of the balloon wall. In another exemplary embodiment, a balloon catheter comprises a catheter having a balloon with an unexpanded and an expanded configuration, and a retractable sheath disposed on the exterior surface of the balloon, wherein the sheath has an inner surface and an outer surface, and further wherein a plurality of fibers outwardly extend from the outer surface of the sheath.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: August 9, 2016
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Barbara E. Stamberg
  • Patent number: 9370642
    Abstract: A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: June 21, 2016
    Assignee: J.W. MEDICAL SYSTEMS LTD.
    Inventors: David W. Snow, Patrick H. Ruane
  • Patent number: 9351736
    Abstract: Assemblies, kits, and methods for occluding a vascular vessel, such as a varicose vein, are disclosed. An assembly can include a removable inner member, a removable outer member, and an elongated expandable member positioned in a compressed form between portions of the inner and outer members. To facilitate their removal, one or both of the inner and outer members can include a handle coupled to a proximal end. The elongated expandable member can include a gelatin material or a collagen material that is configured, when wetted, to expand from a compressed first diametrical size to a second larger diametrical size within a time period of 5 minutes or less. At the second larger diametrical size, the gelatin or collagen material can occlude a vascular vessel for a period of at least 20 days without degrading.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: May 31, 2016
    Assignee: Vascular Solutions, Inc.
    Inventors: Howard Root, James Arnold Murto, Stephen Anthony Penegor, Gregg Sutton
  • Patent number: 9265914
    Abstract: An example of recovery catheter assembly comprises an actuator element and a mechanically radially expandable and contractible recovery device operably connected to the actuator element. The recovery device has proximal and distal blocking portions and a central portion therebetween. The recovery device is at least partially placeable in a first, radially collapsed configuration and in a second, radially expanded configuration by manipulation of the actuator element. When in the second, radially expanded configuration, the proximal and distal blocking portions have radial dimensions greater than the radial dimension of the central portion thereby at least partially defining a collection chamber at the central portion.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: February 23, 2016
    Assignee: NFUSION VASCULAR SYSTEMS, LLC
    Inventors: Richard Eustis Fulton, III, Richard Lotti
  • Patent number: 9216301
    Abstract: Balloon catheter, applicator, particularly for invasive radiotherapy, and method of controlling the balloon catheter with respect to its shape and position in a tissue to be treated prior to an irradiation. The balloon catheter provides a catheter shaft for introducing a probe, an outer balloon and an inner balloon, disposed inside the outer balloon, the inner space of the inner balloon connecting to a channel for connection to a media inlet and intermediate space between the outer balloon and the inner balloon connecting to a channel for connection to a media storage unit. In order that the balloon catheter can be securely controlled with respect to its shape and position in a patient in a simple but clear manner prior to irradiation, the outer balloon is formed of a flexible, non-extendible material and the inner balloon is formed of a flexible, extendible material.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: December 22, 2015
    Assignee: CARL ZEISS MEDITEC AG
    Inventors: Norman Roeder, Matthias Benker
  • Patent number: 9179921
    Abstract: A medical device consists of a dual lumen catheter with three intra-connecting balloons comprising a balloon stent. The adjustable tissue approximation using negative pressure exerted between device and mucosa of stomach/esophagus/colon with improved injury site isolation via adjustable balloon stent and added potential of negative pressure application to injury site for active healing process and distal feeding potential.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: November 10, 2015
    Inventor: Michael Christopher Morris
  • Patent number: 9180274
    Abstract: The invention comprises an indwelling medical device which is capable of delivering a therapeutic agent evenly along the length of the indwelling portion, including the outer wall, of the device.
    Type: Grant
    Filed: September 8, 2011
    Date of Patent: November 10, 2015
    Assignee: W. L. G ore & Associates, Inc
    Inventors: Edward H. Cully, Jeffrey B. Duncan, Matthew E. Maulding, Claudio Schonholz, Benjamin M. Trapp
  • Patent number: 9108028
    Abstract: A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 18, 2015
    Assignee: Abbott Cardivascular Systems Inc.
    Inventors: Paul M. Consigny, Fozan O. El-Nounou, David C. Gale, Pamela A. Kramer-Brown
  • Patent number: 9089677
    Abstract: A transcutaneous multimodal delivery device for drug delivery and the methods of making and using the same are provided.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: July 28, 2015
    Assignee: The Regents of the University of California
    Inventors: B. Chia Soo, Kang Ting, Ben Wu, Kevin Zhang
  • Patent number: 9084870
    Abstract: The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with some embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube and an elongated member positioned within the tube. The exit holes combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region.
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: July 21, 2015
    Assignee: Avent, Inc.
    Inventors: Jose Castillo Deniega, Roger Massengale, Kenneth W. Rake
  • Patent number: 9050402
    Abstract: A method of administering a reduced pressure tissue treatment to a tissue site includes percutaneously inserting a tube through a skin tissue of a patient to place a distal end of the tube adjacent the tissue site, the tube having at least one passageway. A balloon associated with the tube is positioned adjacent the tissue site, and the balloon is inflated to dissect and form a void adjacent the tissue site. A manifold having a plurality of flow channels is delivered through the passageway to the tissue site. The manifold is positioned such that at least one of the flow channels is in contact with the tissue site, and a reduced pressure is applied to the tissue site through the flow channels of the manifold.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: June 9, 2015
    Assignee: KCI Licensing, Inc.
    Inventors: Royce W. Johnson, Larry D. Swain, Douglas A. Cornet, Michael Manwaring, Jonathan Kagan
  • Publication number: 20150132409
    Abstract: Agents and devices for affecting nerve function are described. In some variations, a combination of agents, e.g., a cardiac glycoside, an ACE inhibitor, and an NSAID are delivered to affect nerve function. The agent may be delivered locally in a site-specific manner to a targeted nerve or portion of a nerve. For example, the agent may be delivered locally to the renal nerves to impair their function and treat hypertension. One variation of a delivery device includes one or more needle housings supported by a balloon. A delivery needle is slidably disposed within a needle lumen of each needle housing.
    Type: Application
    Filed: May 7, 2013
    Publication date: May 14, 2015
    Inventors: Emily A. Stein, Christina D. Swanson, Michael A. Evans, Kondapavulur T. Venkateswara-Rao
  • Patent number: 9023076
    Abstract: An embolic frame having looped support struts. The frame configuration provides enhanced longitudinal compliance, improved sealing against a vessel wall, low profile delivery, and a short deployed length. The looped support struts have a high degree of “radial” stiffness with a low degree of “longitudinal” stiffness. In the deployed state, the frame exerts a relatively high stress onto a vessel wall to maintain an effective seal, yet remains compliant in the longitudinal direction. The looped support struts elongate when tensioned and assume a compressed and essentially linear form. While constrained in this linear state by a delivery catheter, the support struts exert minimal stress onto the delivery system. The overall delivery profile and stiffness are therefore reduced. When the delivery catheter constraint is removed during deployment, the struts “snap open” and assume a looped configuration which exert a high degree of force onto the vessel wall.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: May 5, 2015
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Michael J. Vonesh
  • Publication number: 20150100040
    Abstract: A medical material supply device which can percutaneously supply a material for nerve regeneration that promotes the regeneration of a nerve is insertable into a vessel and includes: a supply section configured to penetrate from an inner wall to an outer wall of the vessel at a predetermined position in the vessel, thereby being able to supply a material for nerve regeneration to the outer wall of the vessel; and an elongated body which is inserted into the vessel, in which the supply section is provided with a linear portion which is provided at the elongated body and is configured to penetrate from the inner wall to the outer wall of the vessel.
    Type: Application
    Filed: October 8, 2014
    Publication date: April 9, 2015
    Inventors: Risato KOBAYASHI, Ichirou HIRAHARA
  • Publication number: 20150080795
    Abstract: The present invention is directed in various methods, devices and systems relating to providing a balloon on a sheath in combination with orbital atherectomy in order reduce the number of steps in the procedure. In certain embodiments, the balloon comprises adjunctive low pressure balloon for prevention of vessel trauma during dilatation.
    Type: Application
    Filed: July 24, 2014
    Publication date: March 19, 2015
    Inventors: Richard C. Mattison, Robert E. Kohler, Victor L. Schoenle
  • Patent number: 8968511
    Abstract: An inflatable balloon cuff may be adapted to seal a patient's trachea when associated with an endotracheal tube. These cuffs may include indicia that facilitate attachment of the cuff relative to the tube to reduce manufacturing variability for such characteristics as rotational and length alignment. Such indicia may include protrusions that are formed in the wall of the cuff collars or may include visual indicators, e.g., colorimetric or shape-wise indicators. Cuffs with improved attachment relative to the tube may have increased sealing performance.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: March 3, 2015
    Assignee: Covidien LP
    Inventors: Aaron D. Macan, Dhairya K. Mehta, Sarah L. Hayman, Jon W. Neal, Mark R. Behlmaier
  • Publication number: 20150032087
    Abstract: A device for treating the lumen of a living body includes a shaft insertable into a blood vessel, and a balloon provided on the shaft and shiftable between a deflated state and an expanded state. In the expanded state, the balloon has a recessed portion configured to form a coating chamber which is substantially blocked between an inner surface of the blood vessels and the device for treating the lumen of a living body, a discharge port provided on the recessed portion to discharge a coating substance toward the coating chamber; and a suction port provided on the recessed portion to apply a negative pressure to the coating chamber.
    Type: Application
    Filed: July 28, 2014
    Publication date: January 29, 2015
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Hideaki SHIBATA, Naoki ISHII, Satoshi SAWADA
  • Patent number: 8920403
    Abstract: A catheter and method for draining a bladder and injecting a two part biologic adhesive is provided. The catheter has a tubular body extending between proximal and distal ends. A balloon is located adjacent the distal end with a first port extending between the proximal end and the balloon providing for inflation an deflation of the balloon. A second port extends substantially between the proximal end and the distal end for drainage. A pair of ports separate from one another and from the first and second ports extend between the proximal end and the balloon. The pair of ports are each arranged in fluid communication with separate openings located between the balloon and the proximal end to provide separate fluid flow paths for the separate components of the two part biologic adhesive between the proximal end and the openings.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: December 30, 2014
    Inventor: Anthony Doerr
  • Publication number: 20140378896
    Abstract: The present invention relates to a balloon (1) for treating stenosis and the method for obtaining this balloon. The method comprises the steps of: bringing the balloon in the deployed configuration; placing a plurality of stylets (17) that are arranged in the axial direction along the outer wall (10) of the balloon, pushing the stylets towards the balloon core (11) in the radial direction such as to form a plurality of laps (12); laying the laps about the core in the tangential direction such as to lay each lap on an adjacent stylet; removing the stylets such as to form a plurality of cavities (13) comprised between each lap and the balloon core; filling the cavities with the drug.
    Type: Application
    Filed: September 10, 2014
    Publication date: December 25, 2014
    Inventor: Andrea Venturelli
  • Patent number: 8911399
    Abstract: Balloon catheters, and methods of treatment therewith, are provided including an inflatable first balloon at least partially enclosed by an expandable second balloon that has holes. The annular space between the first balloon and the second balloon is configured to promote delivery of the fluid evenly through holes in the second balloon to avoid problems of underloading and/or overloading. Preferably, the annular space is in communication with the holes, and the annular space is configured to receive and then to release and distribute the fluid via the holes in a substantially uniform manner such that even amounts of fluid are released in the distal and proximal holes. The first balloon may have various configurations including being tapered relative to the second balloon. The second balloon may also be tapered accordingly. The device may also include raised portions disposed in the annular space and configured to define channels having various configurations.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: December 16, 2014
    Assignee: Cook Medical Technologies LLC
    Inventor: Scott E. Boatman
  • Patent number: 8900185
    Abstract: A catheter system for localized delivery of a therapeutic or diagnostic agent within a vessel is provided. The system provides for adjustability of the length of the treatment area and for reducing of pressure within the treatment area. The catheter system includes an inner elongated element, an outer elongated element positioned coaxially with respect to the inner elongated element, a blood-release element at a distal end of the inner elongated element and a supply elongated element coaxial to the outer elongated element. A proximal occlusion element is positioned at the distal end of the outer elongated element, proximal to an outlet port. A distal occlusion element is positioned at a distal end of the inner elongated element. The distal end of the inner elongated element is distal to and movable with respect to the outer elongated element distal end.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: December 2, 2014
    Assignee: ThermopeutiX, Inc.
    Inventors: Ronald Jay Solar, Yoav Shaked, Glen Lieber