Abstract: A syringe assembly comprises a syringe barrel having an elongated body defining a chamber for retaining fluid, an open proximal end, a distal end and a frusto-conically shaped tip extending from the distal end and having a passageway therethrough in fluid communication with the chamber. The chamber has an inside diameter of at least 13.5 mm. A stopper is in fluid-tight engagement inside the barrel. An elongated plunger rod extends proximally from the stopper through the open proximal end of the barrel. A flange is positioned at the proximal end of the plunger rod. The flange is shaped and positioned to limit the distal motion of the plunger rod in the barrel by contacting the proximal end of the barrel. A tip cap is releasably connected to the tip for sealing the passageway and the chamber contains injectable liquid.

Abstract: A reconstitution assembly includes: a flexible bag containing a diluent; a drug vial containing a drug; a reconstitution device further comprising: a first sleeve connected to the first container; a second sleeve connected to the second container, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position; a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.

Abstract: An injection device tip includes a body configured to be removably connected to an injection device. A needle has a first portion projecting out from the body and a second portion projecting into a space within the body. The body includes at least one of; at least one slot separating flexible portions which can be deflected outwardly to cause release of an engagement between the body and a proximal end of the injection device, at least one slot separating flexible portions which can be deflected outwardly to cause release of a thread engagement, at least one frangible connection arranged on the body, at least one indicator arrangement on the body which provides a visual indication that the pen needle has been previously used, and at least one spacing separating two generally semi-circular or generally semi-cylindrical flexible portions which can be deflected outwardly.

Abstract: A container of an injectable solution is disclosed herein including various sensors, electrodes, a memory device, and other features that monitor the process of extraction or injection of the content of the container to ensure it is completed successfully in an automated manner, such as in an automatic injecting device.

Abstract: An anti-tampering apparatus and method for drug delivery devices provides for the capture of caps in a manner that restricts repositioning of a captured cap onto a corresponding drug delivery device. The anti-tampering apparatus includes one or more retention members to define a capture region for restrainably capturing a cap. The anti-tampering apparatus further locates an obstruction surface thereof to engage a surface of a drug delivery device and thereby restrict recapping of the device by the captured cap. As such, tampering of a drug delivery device is indicated by the absence of a cap captured within the anti-tampering apparatus.

Abstract: A puncture needle assembly has a needle tube, a protector capable of moving between a first position at which the protector covers the tip of the needle tube and a second position at which the tip is exposed, a body for movably supporting the protector and having an elastic deformable section, and an engagement preventing member removably mounted to the base end of a protector body. The protector has a rib. A portion on the head end side of the rib forms a contact section, and a portion on the base end side of the rib forms an engaging section engaging with the elastic deformable section. When the protector moves from the first position to the second position, the engagement preventing member moves together with the protector to prevent the engaging section from engaging with the elastic deformable section and elastically deforms the elastic deformable section.

Abstract: A retractable safety syringe may comprise a needle, needle holder, syringe body, and a plunger. A proximal portion of the body and a piston of the plunger may define a variable vacuum compartment. A through hole pneumatically connecting ambient air and the variable vacuum compartment may be formed through a thumb platform and rigid shaft of the plunger for allowing air to escape out of the variable vacuum compartment when a piston of the plunger is traversed toward the retracted position and allow air to be introduced into the variable vacuum compartment when the piston is traversed toward the engaged position. A retraction force may be created by the variable vacuum compartment by covering an entrance of the through hole and traversing the piston to the engaged position. At the engaged position, the piston may engage the needle holder and the retraction force may retract the piston, needle holder and needle into the syringe body to prevent accidental needle pricking and needle reuse.

Abstract: This invention relates to methods, apparatuses and systems for testing the functionality of the pumping mechanism of a medical device, e.g., an implantable infusion pump, while the medical device is contained within a shipping package. The test apparatus enables such functional verification, without opening the shipping package, when the medical device is still contained within the package that has been appropriately sealed to maintain sterility of the medical device.

Abstract: A medication injection supervisor device, in one example embodiment, comprises a particular sleeve, the particular sleeve being designed to lock onto to a prefabricated injection pen of a particular design, a universal header designed slide onto the particular sleeve irrespective of the particular model of the prefabricated injection pen, an electronics assembly housed by the universal header, a sensor to detect an injection automatically, the sensor being communicatively coupled to the electronics assembly, a display to display injection data, and a button to allow manipulation and display of the injection data, including resetting of the time. The medication injection supervisor device can infer the completion of the injection from a plunger of the injection pen being depressed.

Abstract: A pen needle assembly includes a cap for covering the non-injection end of a needle of a pen needle. The needle is received by a hub, which is disposed in an outer cover. The cap is adapted to be connected to the outer cover in a first or second position. The cap is removable in the first position and the cap is locked to the outer cover in the second position.

Abstract: An auto-injector automatically dispenses a predetermined dose of medicament upon activation. The auto-injector includes a needle cover operative to engage an injection site and activate the injector. The needle cover is configured to move from a locked retracted position prior to a medicament dispensing operation to a locked extended position after the medicament dispensing operation. The non-removable needle cover prevents contact with the needle both before and after the medicament dispensing operation.

Abstract: A pre-filled hypodermic syringe includes a tubular body having two open ends and containing a fluid to be administered to a patient; a plunger which, having at one of its ends a piston mounted to slide in the tubular body, passes through the opening of the first end of the tubular body; a tip for connection in the form of a cone of the Luer or Luer-Lock type, for example for connecting to a needle or to a drip, intended to pass the fluid that is to be administered and comprising a tubular part communicating with the opening of the second end; the tip comprising an obturator connected by a frangible region to the free end of its tubular part, the syringe being made of a synthetic material and obtained by molding, the obturator being molded as one piece with the tip and the tubular body.

Abstract: The present invention relates to a safety pen needle device comprising a generally tubular hub having a proximal and a distal end, said hub comprising attachment means arranged at its distal end for attaching the safety pen needle device to a medicament container assembly, and a coaxially arranged needle attachment member; an injection needle having an injection end and a non injection end, said injection needle being attached inside said hub and extending through the needle attachment member; wherein said device further comprises a generally tubular rotatable sleeve rotatable arranged on said hub, said rotatable sleeve comprising on its outer circumferential surface at least one guide track comprising flexible means; a generally tubular needle shield slidably arranged on said rotatable sleeve, said needle shield comprising at least one guide protrusion on its inner circumferential surface, wherein said at least one protrusion is arranged to interact with said at least one guide track and with said flexible m

Abstract: The present invention relates to a device for creating a vascular access for extracorporeal blood treatment including an electrically conductive puncture needle with a proximal endpiece, a distal endpiece, and a base body made of electrically non-conductive material into which the distal endpiece is inserted. In a properly arranged vascular access, the base body, including an electrically conductive contact element, lies on the skin of the patient, when the puncture needle is located within the vessel of the patient. A disconnection or dislocation is detected by the impedance between the electrically conductive puncture needle and the electrically conductive contact element being measured and compared to a limit value. If the impedance measured is within predetermined limits, this indicates a properly arranged vascular access. A disconnection or dislocation of the puncture needle leads to a strong variation in the impedance.

Abstract: A single-use ostomy appliance is described including an ostomy coupling for releasable coupling first and second portions at a stomal orifice. The two portions may be separable body-side and non-body-side parts, or the two portions may be portions of a unitary ostomy device such as a controlled evacuation device. The coupling includes a mechanical fastener configured such that the coupling is rendered substantially not resecurable after the fastener is released.

Abstract: A syringe cylinder comprising an interior space, having a stopper that can be displaced in the interior space and delimits an active ingredient space, is proposed. The syringe cylinder is characterized by an indicator device biuniquely indicating a longitudinal movement of the stopper occurring in one direction.

Abstract: A safety injector comprises a needle hub attached by a needle, a hollow barrel for engaging with the needle hub and guiding the needle hub to retract into the hollow barrel, and a plunger combination settled in the hollow barrel. The plunger combination comprises a retractable plunger and a hollow plunger partially telescoped with the retractable plunger, wherein at least one raised portion is formed on an outer wall of the retractable plunger and at a telescoping portion for engaging at least one depression formed on an inner wall of the hollow plunger so that when the plunger combination continuously receives a pushing force after the safety injector is used to perform the injection operation, the retractable plunger can smoothly retract into the hollow plunger. Consequently, a space in the hollow barrel can be spared for accommodating the retracted needle hub.

Abstract: A syringe assembly includes a syringe barrel having an inside surface defining a chamber, an open proximal end, a distal end, and an outlet; a plunger assembly disposed at least partially within the syringe barrel, including an elongate plunger rod having a locking flange formed thereon; and a plunger head having a distal sealing surface, the plunger rod being engageable with the plunger head such that the plunger rod is adapted to move the plunger head within the chamber of the syringe barrel through an injection cycle; and a flange lock disposed at the open proximal end of the barrel. The flange lock is integral with the open proximal end of the syringe barrel. During the injection cycle, the flange lock engages the locking flange of the plunger rod so as to prevent removal of the plunger rod from the syringe barrel.

Abstract: The present invention relates to an injection device (1) comprising: —a container (5) receiving a product, and provided with an injection needle (6), —a housing (9, 11) receiving said container, said container being movable relative to said housing between an initial position, an insertion position, and a final position, —retaining means (12, 15), for maintaining said container in said insertion position, —deactivating means (20), for releasing said retaining means, said device being characterized in that it comprises: —temporizing means (19, 26, 27), for controlling the release of said retaining means until substantially all of the product contained within said container has passed through said injection needle before said container moves to said final position, and —a needle shield (2) coupled with said housing (9, 11) removal of said needle shield being with limited or no rotation of said needle shield. The invention also concerns a kit comprising such a device.

Abstract: A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethylenedioxythiophene, poly(p-phenylene vinylene) and mixtures thereof.

Abstract: A dispenser head for mounting on a fluid dispenser, said dispenser head comprising a body (1) provided with a dispenser orifice (10), said head being provided with a cap (2) that is displaceable between a closed position, in which it covers said dispenser orifice (10), and an open position, in which it does not cover said dispenser orifice, said cap (2) being connected in permanent manner to said body (1), regardless of the position of said cap.

Abstract: A method for determining status of an implanted catheter includes acquiring raw pressure data from a pressure sensor of in an implantable infusion device. The pressure sensor is in communication with a lumen of the catheter operably coupled to the infusion device. The catheter has a delivery region, in communication with the lumen, intended to be positioned in a fluid-filled target location of a patient. The method further includes filtering the raw pressure data to remove the DC component, leaving the AC component within a relevant physiological frequency range; rectifying the AC component to produce a rectified pressure signal; calculating a mean magnitude of the rectified signal; and determining whether the mean magnitude is below a predetermined threshold. If the mean magnitude is below the threshold, the catheter is determined to be in a state other than a normal state.

Abstract: An endoscope plug body comprises a plug frame, a lid member and a plug member and shuts off an inside of a treatment instrument insertion channel from an outside. The plug frame is provided with annular projection portions, a plug body destruction portion and a plug-frame destruction operation portion. A flange portion is arranged between the annular plug portions and fitted to a base of the endoscope. The plug body destruction portion and the plug-frame destruction operation portion releases the lock state by destruction. The plug frame is cylindrical and communicates with a pipe line disposed inside the endoscope. The lid member is separate from the plug frame and has a lid portion disposed at an opening at the other end of the plug frame. The plug member is separate from the plug frame, formed of an elastic member and has a plug-member treatment instrument insertion portion.

Abstract: An auto-injector automatically dispenses a predetermined dose of medicament upon activation. The auto-injector includes a needle cover operative to engage an injection site and activate the injector. The needle cover is configured to move from a locked retracted position prior to a medicament dispensing operation to a locked extended position after the medicament dispensing operation. The non-removable needle cover prevents contact with the needle both before and after the medicament dispensing operation.

Abstract: A puncture needle assembly has a needle tube, a protector capable of moving between a first position at which the protector covers the tip of the needle tube and a second position at which the tip is exposed, a body for movably supporting the protector and having an elastic deformable section, and an engagement preventing member removably mounted to the base end of a protector body. The protector has a rib. A portion on the head end side of the rib forms a contact section, and a portion on the base end side of the rib forms an engaging section engaging with the elastic deformable section. When the protector moves from the first position to the second position, the engagement preventing member moves together with the protector to prevent the engaging section from engaging with the elastic deformable section and elastically deforms the elastic deformable section.

Abstract: A pen needle assembly includes a cap for covering the non-injection end of a needle of a pen needle. The needle is received by a hub, which is disposed in an outer cover. The cap is adapted to be connected to the outer cover in a first or second position. The cap is removable in the first position and the cap is locked to the outer cover in the second position.

Abstract: A pre-filled syringe assembly having a tamper evident tip cap is provided for indicating if the contents of the syringe assembly have been compromised. The syringe barrel has an interior chamber which defines a pressure therein and is sealed at the proximal and distal ends by a first and second seal, respectively, to maintain this pressure. The second seal is formed of a deformable material and a tip cap is located about the second seal and distal end of the syringe barrel. This tip cap includes a viewable indicator representing a change in state of the syringe contents. The indicator has a portion positioned in contact with the second seal such that the first distinguishing feature is viewable through a portion of the cap. Tampering of the contents within the interior chamber causes a change in pressure and movement of the indicator indicating tampering of the syringe assembly.

Abstract: A chemical liquid injection system which a piston driving mechanism is driven only when a cylinder holding mechanism appropriately holds liquid syringes of various sizes through a cylinder adapter and such manner. When the liquid syringe 200S of a size other than the maximum size is appropriately held by the cylinder holding mechanism 120, RFID chip 230 is located on the side at the rear of metallic cylinder holding mechanism 120. A pair of resonance antennas are disposed on the left and right of the RFID chip, and an RFID reader 131 is disposed below the resonance antennas. When the liquid syringe 200S is appropriately held by the cylinder holding mechanism 120, RFID chip 230 wirelessly communicates with RFID reader 131 favorably, and the piston driving mechanism can be operated only in this state.

Abstract: The present invention relates to a device and a method for monitoring a patient access, particularly for monitoring the venous vascular access in extracorporeal blood treatment where blood is withdrawn from the patient via a flexible arterial line which has an arterial needle or cannula, and provided to the patient via a flexible venous line which has a venous needle or cannula. The needle or cannula of the present invention is so designed that, due to the liquid flowing through the needle or cannula, air is drawn in if the needle or cannula is out of the vascular access, whereby sound is generated. A vascular access which is not in proper order is detected with great certainty and reliability by monitoring the surrounding environment for the occurrence of sound, particularly for the occurrence of the solid-borne sound which propagates along the flexible venous line of the extracorporeal blood circuit.

Abstract: A medication injection supervisor device, in one example embodiment, comprises a particular sleeve, the particular sleeve being designed to lock onto to a prefabricated injection pen of a particular design, a universal header designed slide onto the particular sleeve irrespective of the particular model of the prefabricated injection pen, an electronics assembly housed by the universal header, a sensor to detect an injection automatically, the sensor being communicatively coupled to the electronics assembly, a display to display injection data, and a button to allow manipulation and display of the injection data, including resetting of the time. The medication injection supervisor device can infer the completion of the injection from a plunger of the injection pen being depressed.

Abstract: A handling device for use with a medical injector (11) including a protective sheath (17) for a needle (14) has a carrier (20) with an outer cylindrical wall (21) and a coaxial inner tube (33) which is a close sliding fit over the protective sheath (17). A cylindrical sleeve (24) is slidably mounted within the outer cylindrical wall (21) and is adapted to receive the cylindrical body (12) of the injector (11). A bushing (25) is slidably retained within the cylindrical sleeve (24) and is configured to receive a boss (13, 15) supporting the needle (14) at the forward end of the injector body, a spring (29) urging the bushing (25) towards the rear of the sleeve. A plug (35) is mounted on the carrier (20) and is engaged by the forward end of the protective sheath (17) when the injector is received within the cylindrical sleeve, so that the plug is projected forwardly from the carrier when the injector is fully engaged.

Abstract: Injection apparatus having a pre-filled syringe provided with a safety needle assembly, and a sleeve open at one end for containing the syringe with the safety needle assembly projecting from the open end of the sleeve. A cap is fitted to the open end and is configured to receive the projecting part of the safety needle assembly. A seal secures the cap to the sleeve. Following breaking of the seal, the syringe is removed from the sleeve and the cap is removed from the safety needle assembly so permitting the syringe to perform an injection. Thereafter, the syringe is reinserted into the sleeve with the safety needle assembly nearer the closed end of the sleeve, an internal rib in the sleeve co-operating with the safety needle assembly to retain that assembly in the sleeve.

Abstract: A closure piece (1) for a medical syringe is provided, the syringe having a syringe barrel (3) and a syringe neck (23). The closure piece has an adapter (6) which can be fitted onto the syringe neck (23). A screw-type closure piece (4) can be fitted onto the adapter (6). A twist-off ring (13) is connected to the screw-type closure piece (4). A closure cap (5) can be introduced into the syringe neck (23).

Abstract: A device (1) for medical use, of the prefilled ready-to-use syringe type, comprising a tubular body (2) comprising, at its distal end (4), a tip (5) to take a needle and, at its proximal end (12), a piston (3) able to slide inside the said tubular body (2), the said piston (3) being arranged in an initial position, with respect to the tubular body (2), defining an internal working volume (8) at least partially filled with a medicinal liquid (9), the piston (3) being connected to a rod (11) for actuating the said piston, characterized in that the tubular body (2) is provided, on its internal face (13), with a means (14) of detecting the movement of the piston (3), the said means (14) being situated between the initial position of the piston and the proximal end (12) of the tubular body (2). The present invention also relates to a method for manufacturing such a device.

Abstract: An improved tamper evident end cap assembly for a drug loaded syringe which assembly includes a syringe cap to close the discharge port in the nozzle of the syringe and an indicator ring about the nozzle connected by chads or tabs to a tubular shield which chads or tabs are adapted to break freeing the ring from the shield to loosely wobble on the nozzle indicating tampering if an axial force of separation is applied to the syringe cap to remove it from the syringe and a one way drive mechanism engaging both the shield and syringe cap so the shield may be rotated to advance the assembly onto a syringe nozzle but which is not responsive to counter rotation to withdraw the syringe cap to open the discharge port and gain access to the drug.

Abstract: The present invention provides a reservoir compartment adapter for use with a fluid delivery device. The adapter includes a first end adapted for coupling with a fluid delivery device, a second end adapted for coupling with a connector, and a structure between the first end and the second end including an interior space for receiving the reservoir, wherein an extended reservoir compartment for accommodating the reservoir is adapted to be formed when the first end is coupled to the fluid delivery device, and the reservoir is adapted to be secured in the extended reservoir compartment when the connector is coupled to the second end. The adapter allows a user of a delivery device accommodating reservoirs of a certain size to manage periods where increased medication dosage is needed without the burden of carrying a larger delivery device for accommodating reservoirs filled with the increased dosage.

Abstract: An extravascular system for accessing the vasculature of a patient may include a catheter adapter, a needle, and/or a needle tip shield assembly. The needle tip shield assembly may have a needle cap, and the needle cap may have a needle shield and at least one low friction surface. The needle may be disposed within the catheter assembly and the needle tip shield assembly. The low friction surface may reside between the needle shield and the needle. The at least one low friction surface may reside on the needle, on the V-clip, and/or on a structure located between the needle and the V-clip.

Abstract: The present invention monitors an IV bag injection port and informs the user of prior injections. The present invention employs an object and/or a sealed chamber within a transparent IV fluid bag injection port. In the case of the object, notification of prior use is achieved when the object's or IV fluid's appearance is altered. With respect to the sealed chamber, the chamber's seal is breached to allow fluid to pass between the chamber and the IV bag to change the appearance of the contents of the chamber. Since the injection port and bag walls are at least partially transparent, medical personnel are able to observe the altered appearance of either the object, IV fluid or the sealed chamber.

Abstract: According to one exemplary embodiment, a tamper evident cap for placement on a syringe includes a first section for placement about a luer tip of the syringe and a second section for placement above the luer tip when the cap is placed on the syringe. The second section has a slot formed therein that is defined by a ceiling and an opposing floor. The cap also includes a slider received within the slot and being slideable in the slot from at least an open position where the luer tip is accessible through the second section for filling the syringe and a locked position where the luer tip is covered by the slider and access to the luer tip is prevented.

Abstract: An implantable drug infusion pump for delivering drug therapy is made more reliable and its performance improved by monitoring drug pump temperature. Monitoring pump temperature can also provide for temperature-related drug therapy modification. A pump temperature sensor is read by the infusion pump's microprocessor. Pump temperature data is stored in pump memory for later access by a remote controller. A simple thermistor or semiconductor temperature sensor can provide fast and reliable temperature monitoring of the pump and/or of a patient by reading the temperature sensor's value and calculating a temperature therefrom.

Abstract: A device for detecting pressure and/or temperature changes in a fluid-channel and method thereof are disclosed. The device includes a main duct with an inlet and an outlet, a branch ductwork with a first branch end branching off the main duct downwards the inlet and with a second branch end discharging into the main duct upwards the outlet, and at least one dead-end channel with a first end that branches off the branch ductwork and a second closed end. The dead-end channel is adapted to trap a gas bubble within the dead-end channel when the device is primed or filled with a liquid fluid, wherein the gas bubble changes its size or position if a change in pressure or temperature occurs in the device.

Abstract: An infusion pump assembly includes an enclosure assembly. A reservoir assembly is positioned at least partially within the enclosure assembly and is configured to contain an infusible fluid. A pump assembly is positioned at least partially within the enclosure assembly and is configured to effectuate the dispensing of the infusible fluid contained within the reservoir assembly. Processing logic is positioned at least partially within the enclosure assembly and is configured to control the pump assembly. A removable cover assembly is configured to releasably engage the enclosure assembly. A combination of the removable cover assembly and at least a portion of the enclosure assembly defines a power supply cavity configured to prevent a removable power supply assembly from being reverse-polarity electrically coupled to the processing logic.

Abstract: A method for determining the status of a catheter of an implanted infusion system, where the catheter is intended to deliver a fluid composition to CSF of a patient, includes monitoring catheter pressure, developing a pressure modulation profile based on the monitored pressure, and comparing the developed pressure modulation profile to a predetermined pressure profile. The predetermined pressure profile may be a profile of cerebrospinal fluid or a bolus infusion or withdrawal profile for the catheter. A determination of catheter status, such as properly functioning, occluded or leaky, can be made based on the comparison.

Abstract: A safe medical-drug injector with a collapsable plunger combination thereof is proposed. The injector includes a hub connected with a needle, a hollow barrel, and a collapsable plunger combination including a hollow cannula and a retractable plunger that is telescoped with the hollow cannula. At least a stress adjustable notch is formed at the core of the retractable plunger or in an upper edge of the hollow cannula, and at least one raised portion is formed on an outer lateral side of the retractable plunger near the stress adjustable notch to be correspondingly embedded with at least a depression formed on an inner lateral side of the hollow cannula. The engagement between the raised portion and the depression is released to make the retractable plunger drawn back to the hollow cannula when a following press is applied on the hollow cannula after the safe medical-drug injector completes an injection.

Abstract: Medical injectors are described herein. In some embodiments, an apparatus includes a medicament container, a needle assembly, a coupler, and a retainer. The medicament container has a distal end and a proximal end and is configured to contain a medicament. The coupler is configured to couple the needle assembly, which includes a needle and a hub, to the distal end of the medicament container. The retainer is configured to be coupled to the needle assembly and the medicament container. The retainer is configured to limit the movement of the needle assembly when the coupler fails to maintain the position of the needle assembly relative to the distal end of the medicament container.

Abstract: Containers for automatic injectors and automatic injectors adapted for those containers are disclosed. The containers include structures adapted to retain and, optionally, cripple the needle of the automatic injector when the automatic injector is inserted into the container after use. Depending on the embodiment, an indicator may be included, either as part of the container or as part of the automatic injector, to indicate whether or not the automatic injector has been used. If the indicator is provided as a part of the automatic injector, a corresponding portion of the container may be formed of a light permeable material. The container may also include features, such as an eyelet over the closed end, designed to cushion the automatic injector. Cushioning and shock absorbing features may also be provided inside the container. A clip is also disclosed. The clip is designed to attach two or more containers together.

Abstract: A tamper evident tip cap assembly for a prefilled dosage syringe having a tip cap wherein a sleeve is frangibly connected to the tip cap, and is captured within an overcap freely rotatable thereon. The tamper evident tip cap assembly is removed from the syringe tip cap by pulling the overcap to break the frangible connection between the sleeve and syringe tip cap.

Abstract: A disposable ophthalmic or medical apparatus has a portion with a color changeable dye disposed thereon. The dye changes color after being exposed to oxygen for a controlled and predetermined period of time indicating that the apparatus should no longer be used.

Abstract: The invention relates to a tamper-proof closure for a medical syringe, comprising a cover cap (7) and a fixing ring (8) for fixing the cap onto the needle base (6) of the syringe cylinder(2). The cover cap (7) and the fixing ring (8) are joined by connecting pieces (14). First projections (16) extend from the cover cap (7) to the fixing ring (8). Second projections (17) extend from the fixing ring (8) to the cover cap (7).

Abstract: This invention relates to methods, apparatuses and systems for testing the functionality of the pumping mechanism of a medical device, e.g., an implantable infusion pump, while the medical device is contained within a shipping package. The test apparatus enables such functional verification, without opening the shipping package, when the medical device is still contained within the package that has been appropriately sealed to maintain sterility of the medical device.