Abstract: The present invention is directed to a housing for a drug delivery device. The housing comprises an outer shell with an aperture, an insert received within the aperture and a clamp attached to the outer shell. The insert has at least one recess which is engaged by a lug of the clamp to retain the insert within the aperture of the outer shell. The invention is further directed to a pen-type injector having such a housing.

Abstract: The present invention relates to a drug delivery device and in particular to temperature sensitive labelling of such devices. The drug delivery device is designed for dispensing of a dose of a medicinal product and comprises a housing, and a drive mechanism comprising an axially displaceable piston rod to act on a piston of a cartridge containing the medicinal product to be dispensed. The device is further provided with a protective cover arranged across a functional component of the device, and adapted to irreversibly change at least one of its visually perceptible properties in response to the ambient temperature rising above or dropping below at least one predefined threshold.

Abstract: Delivery devices and components thereof are disclosed. In an embodiment, a delivery device may include a barrel holding a liquid for delivery. The delivery device may also include a finger flange assembly coupled to the barrel. The finger flange assembly may include a first flange and a second flange each extending laterally from opposite sides of the finger flange assembly, wherein the first flange and the second flange each curve toward the barrel. The delivery device may also include a plunger coupled to the barrel and passing through the finger flange assembly. The plunger may also include a disc-shaped head.

Abstract: The present invention is directed to a pen-type injector equipped with a cartridge holder for a drug delivery device. The cartridge holder has a longitudinal axis and comprises a body for receiving a cartridge, wherein the body comprises at a proximal end engagement means for releasably coupling the cartridge holder to the drug delivery device, a latch member for releasably engaging a cap of the drug delivery device and an alignment element which is visual from the outer side of the body. The alignment element may be an aperture provided in the body and/or a lug which forms the latch member.

Abstract: The invention relates to an injection unit, preferably a pen-shaped injection unit, for administering or delivering a fluid product. The injection unit comprises a housing, an axially movable piston rod mounted in the housing in a non-rotatable manner, a delivery apparatus having a threaded nut that is able to move the piston rod in order to deliver product, a dosing device having a dosing sleeve, a rotary knob, a discharge button arranged coaxially on the dosing sleeve, and a receptacle for the product. The dosing device is connected to the delivery apparatus via a coupling mechanism, wherein the coupling mechanism includes of at least two coupling surfaces that each carry a toothing comprising teeth, wherein the coupling surfaces are used to generate an acoustic and/or tactile signal corresponding to the set or corrected dose of the product to be administered during the dosing operation or during correction of the dose.

Abstract: The present invention relates to medical devices, in particular autoinjectors and syringes having one or more thermochromic response indicators that are sensitive to temperature changes of a drug formulation or solution. The present invention provides for a pre-filled delivery device comprising a syringe, a cartridge, or a capsule having a barrel, where the barrel is marked on the outer surface with a first thermochromic indicator, and wherein the thermochromic indicator is responsive to temperature changes of the drug formulation or solution within the barrel.

Abstract: An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.

Abstract: The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut.

Abstract: An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.

Abstract: A medication delivery apparatus for use with a medication container includes a housing, a fluid conduit at least partially extending within the housing and configured to deliver medication within the medication container to a patient, a medication port extending from the housing and configured to be coupled to a fluid outlet of the medication container, the medication port being fluidically coupled to the fluid conduit, and at least one sensor disposed within the housing to generate information characterizing administration of the medication for processing by a remote data collection system. The housing can have a size and shape that enables it to be supported by a first hand of a user while the user administers the medication from the medication container via the medication port using a second hand of the user. Related apparatus, systems, and techniques are also described.

Abstract: Disposable items made from bioplastic resins include a biodegradable resin selected from the group consisting of polylactic acid (PLA), cellulose based PH, polycaprolate (PCL), polybutyleneadipatetetephathalate (PBT), polyhydroxyalkanoate (PHA), green polyethylene (GPE), green polyethylene terephthalate (GPET), poly-D-lactide (PDLA), and poly-L-lactide (PLLA); a plasticizer intermixed with the resin to provide a generally homogenous bioplastic; and a device formed from the bioplastic, where the device is at least one of a multidose syringe, a sharps container, or a suction canister. Embodiments include green indicators.

Abstract: A supplemental device for attachment to an injection device is presented having a display; a processor arrangement; a dose dialled detector operable to detect a dose of medicament dialled into an attached injection device; a dose delivery determiner for determining that a dose of medicament has been delivered; a quantity determiner determining a quantity of medicament that has been delivered; and a clock configured to determine a current time. The processor arrangement is configured when the supplemental device is in a default mode to display both a quantity of medicament that was delivered since a last dose and a time elapsed since delivery of the last dose.

Abstract: The present invention relates to a safety pen needle device comprising a generally tubular hub having a proximal and a distal end, said hub comprising attachment means arranged at its distal end for attaching the safety pen needle device to a medicament container assembly, and a coaxially arranged needle attachment member; an injection needle having an injection end and a non injection end, said injection needle being attached inside said hub and extending through the needle attachment member; wherein said device further comprises a generally tubular rotatable sleeve rotatable arranged on said hub, said rotatable sleeve comprising on its outer circumferential surface at least one guide track comprising flexible means; a generally tubular needle shield slidably arranged on said rotatable sleeve, said needle shield comprising at least one guide protrusion on its inner circumferential surface, wherein said at least one protrusion is arranged to interact with said at least one guide track and with said flexible m

Abstract: The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.

Abstract: A medical assembly includes a syringe and a cover wrapped around the syringe. The syringe is configured to hold and dispense a medicine therein. The cover includes information pertaining to the medicine. The cover is movable between a rolled configuration and an unrolled configuration. The cover includes a re-sealable device to removably couple the cover to itself when in the rolled configuration. The cover includes radiation blocking material to protect the medicine. A method of attaching the cover to the syringe is provided.

Abstract: A driving and dosing device for an injection device includes: a housing, a dosing element gripped by a user, an actuating element actuable by the user to discharge the set dose, a propulsion element for acting on a piston to discharge the set dose, a spring configured to act between the propulsion element and an abutment, which is preloaded so as to discharge a maximum dischargeable product quantity in a plurality of individual discharges, a rotation element configured to rotate relative to the housing and a clutch configured for releasably engaging the rotation element. Releasing the clutch permits the rotation element to rotate relative to the housing when the actuating element is actuated, blocks the rotation of the rotation element relative to the housing when the actuating element is released, and by rotation of the rotation element, the spring is permitted to move the propulsion element in the discharge direction.

Abstract: A driving and dosing device for an injection device for administering a liquid product, in particular a medication, wherein a product dose to be administered can be set by means of the driving and dosing device, comprising: a) a housing, b) a dose indicating element, around the circumference of which a dose scale is arranged, c) a pointing device and a (d) dosing element that can be gripped in particular by the user of the driving and dosing device, wherein the dose indicating element can be rotated, in particular screwed, relative to the pointing device and about an axis of rotation (L) and a value of the dose scale that corresponds to the set dose can be read by means of the pointing device, in order to set the dose to be administered by rotating the dosing element relative to the pointing device, and e); a discharge spring, which stores the energy required for discharging the product, wherein the discharge spring is loaded by means of rotation of the dosing element.

Abstract: Certain exemplary embodiments comprise can comprise an auto-injector, which can comprise: a vial configured to store and/or contain an injectable medicament, the vial defining a vial longitudinal axis, and a housing comprising the vial. In various embodiments, the injectable medicament can be a medicine, medication, drug, pharmaceutical, prescriptive, agent, antidote, anti-venom, hormone, stimulant, vasodilator, anesthetic, and/or nutritional supplement that is substantially ready for injection.

Abstract: A supplemental device for attachment to an injection device comprises an aligning arrangement for ensuring a predetermined positional relationship between the supplemental device and the injection device; and a securing arrangement for securing the supplemental device to the injection device.

Abstract: A system comprising processor means configured to collect and store data, display means controlled by the processor means, and switch means allowing the system to be set in a display mode or a data transfer mode. When the system is in the display mode the processor means is configured to control the display means to display stored data using user-readable numeric values, and when in data transfer mode the processor means is configured to generate a machine-readable-only visual representation of the stored data, and control the display means to display the machine-readable-only visual representation.

Abstract: An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.

Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.

Abstract: A drug delivery device comprising: a device body, an operating member which is configured to be movable relative to the device body for operating the drug delivery device, a preventing member which prevents movement of the operating member relative to the device body for operating the drug delivery device, wherein the preventing member is removable to allow movement of the operating member relative to the device body for operating the drug delivery device.

Abstract: A syringe for use with a powered injector to inject a fluid into a patient that includes a length of material adapted to transmit or propagate electromagnetic energy therethrough. The length of material includes at least a first indicator positioned along the length of material. The first indicator is adapted to interact with at least a portion of the energy being propagated through the length of material in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.

Abstract: A luer port alert device and method of alerting a care provider to a condition of a patient therewith prior to administering fluid treatment to the patient is provided. The luer port alert device includes an arcuate body having a through passage extending along a central axis between opposite ends. A bridge member extends from the body over one of the ends generally along the central axis to at least partially obstruct access to the through passage. The bridge member is selectively and resiliently moveable radially outwardly the central axis under an externally applied force to allow full, unobstructed access to the through passage, when desired, and returns to its relaxed position generally along the central axis upon removing the externally applied force.

Abstract: A disposable syringe including: a syringe cylinder (100) for containing a medicinal liquid therein, in which a medicinal liquid nozzle (120) is formed as a protrusion at a front end of the syringe cylinder, and a piston (110) is provided inside the syringe cylinder; and a medicinal liquid injection hub (200) including a needle (210) and a needle hub (220) and combined with the medicinal liquid nozzle in a removable manner, wherein a combining part (300) is provided in the medicinal liquid nozzle (120) and in the needle hub (220) so as to prevent a leakage of the medicinal liquid and to allow the needle hub to be both easily separated from and easily combined with the medicinal liquid nozzle by a user when using the syringe; without allowing the needle hub to be undesirably separated from the medicinal liquid nozzle.

Abstract: Described are devices and systems for protection of injectable substances such as adipose cells from excessive stress or pressure during injection procedures. Further described are stress control mechanisms for detecting and/or controlling stress or pressure within injection devices.

Abstract: The present invention relates to an automatic torsion spring based injection device having a dial-up/dial-down mechanism by which a dose can be set by rotating a dose setting member in a first direction and which dose size can be reduced by rotating the same dose setting member in a second and opposite direction. The dial-up/dial-down mechanism operates a torsion spring which is strained when setting a dose and unstained when rotating the dose setting element in the second direction.

Abstract: The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut.

Abstract: An injection device includes a housing; a container holder configured for accommodating a medicament container and having a needle attached to one end thereof and a stopper sealingly and slidably arranged inside the medicament container at the other end thereof; a drive unit, including a plunger rod, a plunger driver, and a first energy accumulating member operationally associated with the plunger driver; and an injection indication mechanism, including a tactile signaling element and a drive mechanism for driving the tactile signaling member, the drive mechanism being coupled to the plunger driver.

Abstract: The pharmaceutical syringe unit includes a cylindrical syringe cover having at one end side thereof a needle mount for an injection needle and a piston-inserting portion at the other end side, and a pharmaceutical syringe configured to be loaded in the syringe cover. The syringe cover includes, on an outer surface thereof, a discrimination mark that is detectable by the pharmaceutical injection device and indicates a type of a drug. The syringe cover includes, on an outer surface thereof, a rotation marker that indicates a rotation direction of the pharmaceutical syringe unit with respect to the main body when the pharmaceutical syringe unit is mounted on the main body.

Abstract: The present invention relates to an injection device (1) having a mechanical dose size display wherein a first scale drum (10) carrying a series of first ciphers (11) and a second scale drum (20) carrying a series of second ciphers (21) are both rotatel able and axially moveable relatively to a housing (2) of the injection device in such a way that one of the first ciphers (11) and one of the a second ciphers (21) appears simultaneously in a window provided in the housing (2) thereby informing the user of the set dose. Bothe the first scale drum (10) and the second drum (20) preferable carries five ciphers (11, 21) around one full circumferential perimeter. The ciphers (11, 21) are provided in different circumferential circles and/or helically provided.

Abstract: A system for optimizing a patient's insulin treatment, comprising a drug delivery device (320) with an identifier representing information for a specific drug contained in a reservoir. An accessory device (310) comprises a blood glucose meter (BGM) and a processor programmed to determine for at least two pre-defined specific drugs a recommendation for an amount of the given drug based on a blood glucose value. The recommendation for a given pre-defined drug can be calculated when the corresponding identifier has been captured with the accessory device in a current mounted state, the recommended dose being calculated based on one or more blood glucose values, one or more patient specific parameters as well as parameters for the identified specific type of drug.

Abstract: The invention relates to a gearing mechanism for a dose delivery device wherein the dose can be set by rotating a dose setting member (2, 102), and by which the dose setting member (2, 102) and a push-button (4) elevates from one end of the device proportional to the set dose from a position fixed relative to a housing (1, 101), and by which an injection of the set dose can be done by pressing the push-button back to its not elevated position, moving a piston rod (10, 110) cooperating with the piston in an cartridge (12, 112) and expelling a medicament out of the through a needle. The gearing mechanism is arranged in the device in such a way, that the loss of energy is very low.

Abstract: A drug administration safety device having a label configured to be attached to a drug container such as a syringe or IV bag, an adhesive on the back face of the label, and a backing or substrate for holding the label and protecting the adhesive prior to the application of the label to the drug container. In one embodiment, the label includes a first drug name section in a first orientation, a second drug name section in a second orientation, a third drug name section in a third orientation, a drug concentration section, a variable information section, and a gradiation viewing section. The first orientation, second orientation, and third orientation are different from each other to enable a user to readily see the drug name regardless of the position and orientation of the drug container.

Abstract: The present invention relates to an injection device comprising a torsion spring operatively connected to a dose setting member being adapted to set a dose to be ejected from the injection device. A rotatably mounted display member adapted to display the dose to be ejected in accordance with a setting of the dose setting member is also provided. The rotatably mounted display member is adapted to be rotated over an angle corresponding to at least one revolution of the display member. The display member may be implemented as a dose indicator barrel having numerals arranged along a helical path on an outer surface thereof, or alternatively, as a counting device having two or more display wheels having numerals arranged on an outer surface thereof.

Abstract: Systems, devices, and methods are described for using an autoinjector device. In one aspect, an autoinjector device comprises a housing and a plunger slidably mounted to the housing, the plunger including a tapered region. An actuator urges the plunger with respect to the housing from a storage position to a launch position, and a friction element about a portion of the tapered region resists a movement of the plunger from the storage position to the launch position.

Abstract: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.

Abstract: The syringe systems disclosed herein provide in part devices for allowing patients with compromised joint strength to more easily administer medicine. Certain exemplary syringe embodiments include a handle forming a handgrip, a syringe barrel that magnifies the dosage marks located on an inner barrel, and a tip cap slidably engageable with the syringe barrel for shielding a needle.

Abstract: The present invention relates to a drug delivery comprising a housing (10) adapted to retain a cartridge (16) and a piston rod (26), the piston rod (26) being adapted to drive a piston (28) so as to engage the piston (28) into the cartridge (16) in response to operating an operating button (30), and an indicator means (40) being capable of revealing usage related information of the drug delivery device (5), the indicator means (40) being movable with respect to the housing (10). Furthermore, using indicator means (40) on a drug delivery device (5), wherein the so as to reveal usage related information of the drug delivery device (5), wherein the indicator means (40) being movable with respect to a housing (10) of the drug delivery device (5) is disclosed.

Abstract: A syringe for use with a powered injector to inject a fluid into a patient that includes a length of material adapted to transmit or propagate electromagnetic energy therethrough. The length of material includes at least a first indicator positioned along the length of material. The first indicator is adapted to interact with at least a portion of the energy being propagated through the length of material in a manner that is detectable. The presence (or absence) of the first indicator provides or corresponds to information about the syringe configuration. The indicator(s) of the present invention can, for example, provide information about syringe configuration by the number and/or position thereof. A plurality or set of such syringes can be provided, with the configuration of each such syringe being represented by the presence or absence of indicator(s) of that syringe.

Abstract: Reminder device for indication of time-related information for a pen-shaped medical delivery device, the reminder device comprising: a housing part comprising a guiding device, an adjusting element which is movably disposed on the guiding device for selecting of a position of the adjusting element for indication of a time information, an indication device disposed along the guiding device and having an outer surface with sequential time indicia disposed thereon, wherein the indication device provides a time indication which corresponds to the position of the adjusting element, so that a user can mark a time information on the pen-shaped medical delivery device.

Abstract: System comprising a sensor assembly (3, 4, 5, 6) adapted to measure a magnetic field, and a moveable element (1) adapted to be moved relative to the sensor assembly between two positions by a combined axial and rotational movement, the rotational movement having a pre-determined relationship to the axial movement. A magnet (3) is mounted to the moveable element and configured to generate a spatial magnetic field which relative to the sensor assembly varies corresponding to both the axial and rotational movement of the magnet and thus the moveable element. A processor is configured to determine on the basis of measured values for the magnetic field an axial position of the moveable element.

Abstract: An injection device operable to deliver a dose of medicament from a syringe or cartridge includes a temperature-sensitive arrangement for inhibiting operation thereof under predetermined temperature conditions. This may include a thermally responsive element that adopts a position in which operation of the device is inhibited when a temperature level is passed.

Abstract: The present invention relates to a display arrangement for a drug delivery device, comprising: a first display member comprising numerous surface portions having at least two different but interrelated appearances and being alternately arranged along a first direction, and a second display member comprising a light modulating structure to modulate visible light emanating from the first display member, wherein first and second display members are movably disposed relative to each other along the first direction to simultaneously reveal and/or to conceal at least two surface portions of interrelated appearance.

Abstract: Medication management and reporting technology, in which output from at least one sensor configured to sense physical activity in a building in which medication of a patient is located is monitored and a determination is made to capture one or more images of the medication based on the monitoring. A camera is used to capture an image of the medication and the captured image is analyzed to detect a state of the medication. Information regarding a schedule by which the medication should be taken by the patient is accessed and an expected state of the medication is determined. The detected state is compared with the expected state and a determination is made that the patient has departed from the schedule based on the comparison revealing that the detected state does not match the expected state. A message indicating the departure from the schedule is sent based on the determination.

Abstract: An IV bag/line safety device including a tag set and a bag attacher removably connected to the tag set. The tag set includes a plurality of tags printed with the name of an IV solution. The bag attacher is configured to attach the safety device to an IV bag containing the IV solution printed on the tags. After attachment, the safety device provides visual cues to a user inviting the user to disconnect the tags from the safety device. After disconnecting one or more of the tags, the user may attach those tags to an IV tubing line connected to the IV bag through which the IV solution contained in the IV bag flows from the IV bag into a patient. This enables the user to quickly identify a given IV tubing line having at least one tag attached thereto as containing a particular IV solution.

Abstract: An injection apparatus includes a counter wheel that is incremented by the dose delivery mechanism each time the device is fired. The apparatus includes a final dose disabling mechanism that prevents further usage once the final dose has been delivered. An anti-tamper feature is provided to prevent inadvertent or premature initialisation of the apparatus.

Abstract: The present invention discloses a handheld medical device having a housing, at least one user activatable button mounted on a surface of the housing, and a light source mounted within the housing below the button and arranged to direct light towards the button. Substantially the whole of the button and the surface of the housing adjacent the button are opaque, save for a narrow strip adjacent the periphery of the button which is non-opaque.

Abstract: Included are embodiments of an infusion set for administering a liquid. One embodiment includes an infusion head to be placed on the tissue of a patient, a coupler for connecting the infusion head to an administering device, and a cannula that is configured for connection to the infusion head. Some embodiments include a display device for displaying an application period of at least a portion of the liquid administered using the infusion set.