Injector Or Aspirator Syringe Supported Only By Person During Use (e.g., Hand Held Hypodermic Syringe, Douche Tube With Forced Injection, Etc.) Patents (Class 604/187)
  • Patent number: 11083882
    Abstract: A connector assembly may include a body and a fluid fitting, the fluid fitting configured for releasably engaging a syringe nozzle, at least one deflectable locking arm connected to the body and radially deflectable relative to the distal end, the proximal end of the at least one deflectable locking arm configured for deflecting in a radial direction relative to the distal end to releasably engage the syringe nozzle, and at least one locking element disposed on the at least one deflectable locking arm, the at least one locking element movable with movement of the at least one deflectable locking arm between a first position where the at least one locking element is released from an engagement portion of the syringe nozzle and a second position where the at least one locking element is engaged with the engagement portion of the syringe nozzle.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: August 10, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Matthew Schrauder, Brian Cain, Michael Cousley, Kevin Cowan, Michael Spohn
  • Patent number: 11077442
    Abstract: The disclosed embodiments related to an apparatus and methods for biological sample processing enabling isolation and concentration of microbial or pathogenic constituents from the sample. Sample may be obtained directly from a specimen container, such as a vacutainer, and processed directly without risk of user exposure. The disclosed methods and apparatus provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: August 3, 2021
    Assignee: TANGEN BIOSCIENCES, INC.
    Inventors: John Richard Nobile, John F. Davidson
  • Patent number: 11077242
    Abstract: A blinding cap for covering a rigid needle shield that is covering a needle of a syringe includes an elongated body extending between a proximal end and an opposing distal end, the body at least partially bounding a chamber. An annular sleeve projects from the proximal end of the body and at least partially bounds a channel. A first flange radially inwardly projects from the body into the chamber, the first flange at least partially bounding an opening that provides communication between the chamber and the channel.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: August 3, 2021
    Assignee: Fisher Clinical Services GMBH
    Inventors: Patrick Locati, Guido Hunkeler, Alain Duerr
  • Patent number: 11020530
    Abstract: A syringe body for a prefilled syringe includes: a hollow body portion; a proximal-end opening portion provided at a proximal end portion of the body portion; and a distal-end nozzle provided at a distal end portion of the body portion. The body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer. The body portion has a thick body portion accounting for 80% or more of the body portion along an axial direction. A wall thickness of the thick body portion is 2.23 to 2.40 mm.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: June 1, 2021
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Katsuyuki Takeuchi, Eiji Yagishita, Nobukazu Akaike, Koji Nakamura, Tsutomu Ueda, Kimiya Mori
  • Patent number: 11008243
    Abstract: The invention relates to a method for producing a syringe having a piercing means, comprising the following steps: a) providing a syringe body having a distal end section, which comprises an inner channel that discharges at a distal opening, wherein the distal end section is in a formable state; b) providing a piercing means; c) inserting a proximal section of the piercing means through the distal opening into the inner channel of the distal end section; and d) shaping the distal end section by means of a first shaping tool in such a way that an inner surface of the distal end section contacts at least portions of the piercing means, as a result of which at least portions of the piercing means are secured.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: May 18, 2021
    Assignees: Gerresheimer Regensburg GmbH, Gerresheimer Bunde GmbH
    Inventors: Manfred Baumann, Michael Wiglenda, Claudia Petersen
  • Patent number: 10954352
    Abstract: Provided are methods for surface-modifying a rubber vulcanizate and surface-modified elastic bodies, which can cost-effectively provide a variety of functions, including sliding properties, liquid leakage resistance, and protein adsorption resistance. Included is a method for surface-modifying a rubber vulcanizate as a modification target, the method including: step 1 of forming polymerization initiation points A on the surface of the modification target; step 2 of radically polymerizing a monomer starting from the polymerization initiation points A to grow polymer chains; and step 3 of adding a silane compound to the surfaces of the polymer chains, followed by reaction with at least a fluoroalkyl group-containing silane compound to form modified polymer chains.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: March 23, 2021
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventor: Yasuhisa Minagawa
  • Patent number: 10940269
    Abstract: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: March 9, 2021
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Richard Cronenberg, Michael Quinn, Haiming Wu
  • Patent number: 10926035
    Abstract: The present disclosure relates to a cartridge holder of an injection device, the cartridge holder comprising a tubular shaped elongated sleeve extending in an axial direction to accommodate a cartridge filled with a medicament, wherein the sleeve (29) comprises: a proximal connecting end to connect with a distal connecting end of a body of the injection device, which body is configured to accommodate a drive mechanism of the injection device and which drive mechanism is operably engageable with a piston of the cartridge, a flange section extending radially outwardly from an outside surface of the sleeve and having a proximally facing abutment face to axially abut with a distal end face of the distal connecting end of the body, at least three protrusions located distally from the flange section, extending radially outwardly from the outside surface of the sleeve and being distributed around the circumference of the sleeve.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: February 23, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Christiane Schneider, Martin Vitt, Michael Joest
  • Patent number: 10918799
    Abstract: The present disclosure is generally directed to a drive mechanism for use in a drug delivery device having a cylindrical cartridge, i.e. a handheld injection device for selecting and dispensing a number of user variable doses of a medicament. The drive mechanism includes a base element, a toothed piston rod, which is guided within and movable relative to the base element, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod. The toothed piston rod includes multiple rigid rod pieces which are connected by hinges. The rigid rod pieces comprise a flat plate provided with a straight toothed rack.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: February 16, 2021
    Assignee: Sanofi
    Inventors: William Geoffrey Arthur Marsh, Matthew Meredith Jones
  • Patent number: 10908052
    Abstract: Devices and methods for collecting trace amounts of samples are provided. A device can utilize a sterile syringe integrated with a venturi-type vacuum source for sample collection. The device can be used in a variety of applications for collecting specimens that are otherwise difficult to retrieve using conventional sample collecting techniques.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: February 2, 2021
    Assignee: The Florida International University Board of Trustees
    Inventors: DeEtta Mills, Julian Mendel
  • Patent number: 10857285
    Abstract: The present application relates to an intermediate structure for a support structure of a medicament delivery device, which support structure is to cooperate with a medicament container, said support structure comprising a flexible element arranged to exert a force on a distal end surface of said medicament container, wherein said intermediate structure is arranged between said flexible element and said end surface and arranged to guide said flexible element in an outwardly direction in relation to a longitudinal axis (L) when exerting a force on said medicament container.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: December 8, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Per Klintenstedt, Anders Boström
  • Patent number: 10857295
    Abstract: Described is a medicament delivery device (1) comprising a body (2), a container carrier (7) slidably disposed in the body (2), and a sleeve (6) slidably coupled to the container carrier (7).
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: December 8, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Winfried Huthmacher, Peter Nober
  • Patent number: 10857289
    Abstract: A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device includes a rigid fluid reservoir closed by a septum for use in a fluid dispensing device for dispensing a measured amount of fluid into a living organism, wherein the device has a main housing enclosing the operative components of the device, the said fluid reservoir located within the main housing, an injection assembly including a needle, and a trigger mechanism. The needle has a first end adapted to piercing the septum and pushing the septum into the reservoir so that the septum acts as a piston, expelling the fluid through the needle, and a second end adapted to injecting the fluid into the living organism.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: December 8, 2020
    Assignee: Preci Health SA
    Inventors: Philippe Margairaz, Carlos Da Silva, Luc Maffli, Alain Jaccard, Lucien Vouillamoz
  • Patent number: 10857307
    Abstract: The disclosure relates to a medicament delivery device, comprising: a tubular body having a distal end, a cap adapted to be connected to the distal end (of the body, wherein the body comprises a first clip having a first stop and a first ramp, wherein the cap comprises a second clip having a second stop and a second ramp, wherein the first ramp and the second ramp are adapted to be mutually engaged when the cap is connected to the body in a first position, wherein the first ramp and the second ramp are adapted to resiliently deflect at least one of the first clip and the second clip when the cap is being moved from the first position towards a second position, wherein in the second position the first stop and the second stop abut each other to prevent the cap from being moved into the first position. Furthermore, the disclosure relates to a method for assembling the medicament delivery device.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: December 8, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Marc Schader, Axel Teucher
  • Patent number: 10814068
    Abstract: The disclosure relates to a medicament delivery device, comprising: a tubular body having a distal end, a cap adapted to be connected to the distal end (of the body, wherein the body comprises a first clip having a first stop and a first ramp, wherein the cap comprises a second clip having a second stop and a second ramp, wherein the first ramp and the second ramp are adapted to be mutually engaged when the cap is connected to the body in a first position, wherein the first ramp and the second ramp are adapted to resiliently deflect at least one of the first clip and the second clip when the cap is being moved from the first position towards a second position, wherein in the second position the first stop and the second stop abut each other to prevent the cap from being moved into the first position. Furthermore, the disclosure relates to a method for assembling the medicament delivery device.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: October 27, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Marc Schader, Axel Teucher
  • Patent number: 10799360
    Abstract: A system for treating regurgitation of blood through a diseased heart valve having at least two leaflets can include an implantable, lollipop-shaped device and an adjustment mechanism. The device can have a proximal end portion, a distal end portion, and an intermediate portion extending therebetween. The intermediate portion can include an expandable occluding member having a selectively adjustable diameter and a biocompatible layer attached to at least a portion thereof. The distal end portion can include an anchoring member. The adjustment member can include a distal connecting end that is operatively connected to the proximal end portion of the device. Operation of the adjustment member, after implantation of the device, can cause the diameter of the occluding member to change so that at least one of the heart leaflet coapts with a portion of the occluding member to mitigate or prevent regurgitation of blood through the diseased heart valve.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: October 13, 2020
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Samir Kapadia
  • Patent number: 10786190
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: September 29, 2020
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Phillip Yee, Christopher A. Thomas, Udo Hoss, Lei He, Michael R. Love
  • Patent number: 10772796
    Abstract: Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: September 15, 2020
    Assignee: Medtronic MiniMed, Inc.
    Inventor: Julian D. Kavazov
  • Patent number: 10765812
    Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and as assembling them into syringes, e.g., pre-filled syringes.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: September 8, 2020
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Brian Russell Lilly, Kenneth Wade Kelly, Joseph W. Rogers, Jean-Pierre Giraud, Bruce Rabinne, Benjamin Hunt, Zachary Dean Freeman
  • Patent number: 10729854
    Abstract: The housing for mounting an elongate-shaped container on an injection pen comprises an elongate-shaped body which extends along a longitudinal axis (X30) and which defines an interior volume (V32) for fully receiving the container. The body is provided, on the outside of a first axial end, with at least one first mechanical member for attaching a needle. The body is further provided, in the vicinity of a second axial end opposite the first axial end, with at least one second mechanical member for attaching the housing onto an injection pen. The housing further comprises, in the vicinity of the first axial end thereof, at least one third mechanical member for irreversibly locking a container in position, fully contained in the interior volume (V32) of the body of the housing. Said third locking member is formed by an elastically deformable tab intended to ensure locking of the container in position in the interior volume (V32) of the body of the housing, by axially retaining a flange of the container.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: August 4, 2020
    Assignee: BIOCORP PRODUCTION
    Inventor: Antoine Aneas
  • Patent number: 10653844
    Abstract: An auto-injector for delivering a liquid medicament includes a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end and a telescopic plunger unit arranged between the piston and the proximal end of the housing, the telescopic plunger unit comprising a telescopic frame and a spring element surrounding a plunger element. The plunger element is fixed to a base of the telescopic plunger unit and the spring element is held in an initial compressed state by a compressive force exerted by the base of the telescopic plunger unit. When the spring element is released, a tapering profile of the telescopic frame is configured to provide varying friction with extension such that resistance to telescopic extension decreases as spring force provided by the spring element decreases with increasing extension of the telescopic plunger unit.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: May 19, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 10653847
    Abstract: A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: May 19, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Samuel Steel, Paul Richard Draper, George Cave
  • Patent number: 10632260
    Abstract: The invention relates to a carpoule holder (8) for receiving a carpoule (10) and for fastening to a drive mechanism and/or to a dosing mechanism and/or to a housing (6) of an injection device, with a holding element (9, 9?, 9?) for fastening the carpoule (10) to or in the carpoule holder (8), wherein the holding element (9, 9?, 9?) is designed in such a way that it can be connected to the carpoule holder (8) and can be received completely by the carpoule holder (8).
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: April 28, 2020
    Assignee: TecPharma Licensing AG
    Inventors: Jürg Hirschel, Ulrich Moser, Stefan Burren, Reto Bohner, Bernhard Bigler, Christian Schrul
  • Patent number: 10625025
    Abstract: A prefilled syringe includes a syringe barrel including: a liquid drug discharge portion on a distal end of the barrel, and an opening on a proximal end of the barrel; a cap; a gasket located in the syringe barrel; a plunger including: a shaft portion inserted in the syringe barrel from the opening, and a pressing portion located on a proximal end of the shaft portion and configured to be manually pushed by a user, the plunger being movable toward a distal direction by pushing the pressing portion to slide the gasket toward the liquid drug discharge portion; a liquid drug; an upraised portion located on an inner wall of the syringe barrel between the gasket and the opening; and a clicker.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: April 21, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Junichi Ogawa
  • Patent number: 10625024
    Abstract: The present disclosure relates to a magnifying device attachable to an injection device. The magnifying device includes a frame having a distal end and having a proximal end opposite to the distal end and further has a receptacle extending from the distal end towards the proximal end. The receptacle is accessible from the distal end to receive a proximal end section of the injection device therein. A magnifying lens is fixed to the proximal end of the frame and extending at least partially across the proximal end of the frame.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: April 21, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Zdenek Cerman
  • Patent number: 10617827
    Abstract: The present disclosure relates to a medicament delivery device comprising: a housing (3), a plunger rod received by the housing (3), which plunger rod is rotatable in a first direction relative to the housing (3) and linearly displaceable, an activation button arrangement linearly displaceable from a first position to a second position to thereby rotate the plunger rod in the first direction, a second direction rotation preventer having an annular outer member that is rotationally fixed relative to the housing (3) and an annular inner member partially received by the outer member, wherein the outer member and the inner member are arranged to receive the plunger rod and wherein the inner member is rotationally interlocked with the plunger rod, wherein the outer member and the inner member are structured to allow the inner member to rotate in the first direction relative to the outer member and to prevent the inner member from rotating in a second direction opposite to the first direction, and a recording unit
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: April 14, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Nikolaj Hautaviita, Daniel Säll
  • Patent number: 10598518
    Abstract: A sensor device (2) is removably attachable to a drug delivery device (12). The sensor device comprises an array (20) of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, the drug delivery device having a first movable element (14) which is configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the linear path and to output a signal indicative of an amount of detected light; and circuitry (21) configured to receive the signals output from the optical sensors and, based on the received signals, to determine information associated with a location along the path of the first movable element.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: March 24, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Matthew Jones, Samuel Steel, Barry Yates, Anthony Paul Morris
  • Patent number: 10596327
    Abstract: A drive and dosing device is described for an injection device for administering a fluid product, in particular a medication, wherein the drive and dosing device can be adjusted to a product dose to be administered. The drive and dosing device has, among other things, a coupling which, upon activation of an activation element, enables rotation of a rotation element relative to a housing, wherein by disengaging the activation element, the rotation of the rotation element relative to the housing is blocked.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: March 24, 2020
    Assignee: TecPharma Licensing AG
    Inventors: Susanne Schenker, Ursina Streit
  • Patent number: 10512591
    Abstract: Methods and systems for a cartridge assembly for use with an injection system are provided. An example cartridge assembly may include an ampule containing a pharmaceutical product that is sealed at a distal end with a pierceable diaphragm. The cartridge assembly may also include a hub comprising a proximal portion defining a cavity that is configured to engage the distal end of the ampule and a piercing member positioned within the cavity. The piercing member may include a fluid pathway between a proximal end portion comprising an opening and a distal end in fluid communication with a distal opening of the hub. The proximal end portion may engage the pierceable diaphragm, and the piercing member may apply a force to the pierceable diaphragm in the inactivated position without penetrating the pierceable diaphragm.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: December 24, 2019
    Assignee: Hospira, Inc.
    Inventors: Robert John Oshgan, John C. Tanner, II
  • Patent number: 10500135
    Abstract: A system for filling a fluid reservoir of a fluid infusion device with a fluid is provided. The system includes the fluid reservoir having a first portion and a second portion. A fluid chamber is defined between the first portion and the second portion. The second portion is movable within the first portion and includes an interface. The system includes a transfer guard having a first end and a second end. The first end to be coupled to a source of the fluid and the second end having at least one locking member that couples to the interface. The transfer guard defines a fluid flow path for the fluid from the source, and the transfer guard is movable relative to the first portion to fill the fluid chamber with the fluid.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: December 10, 2019
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Matthew William Yavorsky, Anatoly Aleksandrovich, Edmond W. Yu, Theodore Wilkening
  • Patent number: 10500389
    Abstract: Provided is a system and method for a flared luer connector for medical tubing. More specifically, the flared luer connector includes a tube head adapter formed of a resilient material providing an inlet and opposite thereto an outlet with a longitudinal axis there between. A luer lock fitting is formed proximate to the inlet and structured and arranged to engage a syringe, and at least one flared member disposed between the luer lock fitting and the outlet, the flared member rising from the tube head adapter and angled towards the outlet. The flared member also provides at least one engaging surface between the tube head adapter and a distal edge, the engaging surface acutely angled with respect to the longitudinal axis. The engaging surface is structured and arranged to engage with a corresponding receiving section of a base, the base having a deflector section structured and arranged to deflect a tube head adapter having other than the corresponding flared member.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: December 10, 2019
    Assignee: Repro-Med Systems, Inc.
    Inventors: Andrew I. Sealfon, Siavash Gheshmi
  • Patent number: 10463348
    Abstract: A biopsy device holder includes a needle holder, a distal holder, and a proximal holder. The needle holder includes an elongated housing extending between an open proximal end and a distal end. The needle holder is adapted to releasably receive the biopsy device through the open proximal end. The elongated housing includes a coupler configured to couple the needle holder to the biopsy device. The distal holder includes an opening configured to pivotably receive the distal end of the needle holder. The proximal holder includes a longitudinal stop that engages with a portion of the needle holder to prevent the needle holder from proximal longitudinal movement. The longitudinal stop is configured to disengage the coupler of the needle holder from the biopsy device when the biopsy device is moved proximally in a longitudinal direction.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: November 5, 2019
    Assignee: Devicor Medical Products, Inc.
    Inventors: David Shuart, Andrew Paul Nock, Andrew Robinson, Rachel Yoon Choung, Mark Graham
  • Patent number: 10441712
    Abstract: A device (2) for continuous infusions has a housing (4) in which an infusion appliance seat (6) is provided for receiving an infusion appliance (18) with at least one container (22) that can be pressed empty by means of a ram (20), which infusion appliance seat (6) extends along a main axis of extent (AA) from a ram-side end (26) to an outlet-side end (28). The continuous infusion device (2) moreover has an actuator (30) for automatically emptying the infusion appliance (18), a drive (32) for moving a ram abutment/actuation element (24) of the actuator (30), and a control arrangement (72) by means of which a speed of advance of the actuator (30) is adjustable. Provision is made here that the main axis of extent (AA) of the infusion appliance seat (6) has a predetermined relief angle (W) in relation to a support plane (E) of the housing (4), and here the outlet-side end (28) is arranged above the ram-side end (26) of the infusion appliance seat (6).
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: October 15, 2019
    Assignee: H & B ELECTRONIC GMBH & CO. KG
    Inventors: Tobias Morlok, Wilfried Weber
  • Patent number: 10406282
    Abstract: Provided is a system and method for a removable syringe micro pump. More specifically, the removable syringe micro pump includes a pump housing having a first end and opposite thereto an attaching end, and at least one sidewall there between, the housing having a base proximate to the first end and, the attaching end having an attacher structured and arranged to temporarily engage a syringe. A volute spring is nested within the housing and attached proximate to the base, the volute spring having a compressed first position wherein coils of the volute spring are concentrically disposed under tension such that an initial height of the volute spring is equivalent to a width of a coil, and an extended second position wherein the release of tension extends the volute spring normally away from the pump housing. The volute spring has a diameter pre-selected to pass within a barrel of the engaged syringe.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: September 10, 2019
    Inventors: Andrew I Sealfon, Siavash Gheshmi
  • Patent number: 10368908
    Abstract: The surgical robotic access system provides access for robotic instruments and/or actuators including the introduction, operation and withdrawal of such robotic manipulators into a body cavity without permitting the escape of pressurized fluid or gas. The surgical robotic access system also provides a multi-faceted range of movement without touching or effecting pressure on the opening in the patient's body cavity.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: August 6, 2019
    Assignee: Applied Medical Resources Corporation
    Inventors: Atal C. Patel, Jeremy J. Albrecht
  • Patent number: 10357609
    Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: July 23, 2019
    Assignee: Antares Pharma, Inc.
    Inventors: Thomas Kramer, Matthew H. Rust, Paul M. Goudreau, Peter A. Hoeft, Julius C. Sund, Peter L. Sadowski, Michael Travanty, Patrick Madsen
  • Patent number: 10350362
    Abstract: An automatic medication injection device (20) including injecting progress indicators (82-85) visible along a periphery of the device housing (23). The injecting progress indicators include a flag element (100) which is movable as a drive mechanism (60) of the device advances a sealing plunger (58) within a container of medication (50). The injecting progress indicators are configured to indicate sequentially during a single injection as the flag element moves to cooperatively complete different injecting progress indicators at different times during the single injection, whereby injecting progress of the injection may be monitored by a user.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: July 16, 2019
    Assignee: Eli Lilly and Company
    Inventors: Joseph Daniel Dennis, Jr., Jessica Diane Modlich
  • Patent number: 10314982
    Abstract: A drive assembly for a drug delivery device includes a housing; a number sleeve threadedly engaged with the housing; a dial link rotatably fixed with the number sleeve in a first axial arrangement relative to each other, the number sleeve being rotatable relative to the dial link in a second axial arrangement; a clutch component connected to an inner proximal section of the number sleeve through multiple flexible assembly fingers. The clutch component can engage the number sleeve with the dial link in the first axial arrangement and disengage the number sleeve from the dial link in the second axial arrangement. The drive assembly includes means for preventing an access to the flexible assembly fingers from the outer proximal section of the number sleeve and/or the flexible assembly fingers from flexing inwardly and disengaging from the connection with the inner proximal section.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: June 11, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
  • Patent number: 10314880
    Abstract: The present invention relates to ready to dilute injectable formulations of bortezomib comprising bortezomib, non-aqueous solvents enhancing the solubility and pH modifying agent.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: June 11, 2019
    Inventors: P. Kanteepan, Sagar Laxmanbhai Vekariya, Jayanta Kumar Mandal, Sandip P. Mehta
  • Patent number: 10286153
    Abstract: A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: May 14, 2019
    Assignee: Becton Dickinson France, S.A.S.
    Inventors: Darrin Scott Manke, Christopher Labak, Joseph Omer St. Cyr, David Robert Schiff, Mathieu Dominic Turpault, Antonio Gatta, John Depler Coleman
  • Patent number: 10265474
    Abstract: A drug delivery device is provided with a cartridge holder having at least one guide track, and a body having at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track has a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: April 23, 2019
    Inventors: Christiane Schneider, Tobias Stever, Michael Harms, Ulrik Jakobi
  • Patent number: 10245212
    Abstract: A packaging apparatus is provided for holding a sterile product. In one aspect, a secondary packaging holder is configured with a base and a receiving portion to receive and irreversibly hold a primary packaging holder. The secondary packaging holder can have a substantially planar wall configured to affix an identifying label thereto. The secondary packaging holder can be configured to snap fit to a neck of the primary packaging holder to hold the primary packaging holder such that a portion of the primary packaging holder is exposed outside of the secondary packaging holder based on a height relationship between the secondary packaging holder and the primary packaging holder.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: April 2, 2019
    Assignee: Orbit Biomedical Limited
    Inventors: Chaley Larson, Kostadinka Lilova, Mike Cannamela, William Cagney, Gordon Kosovan, Elaine Hughes, Maria Ficchi
  • Patent number: 10232116
    Abstract: An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: March 19, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Matthew Ekman, Timothy Donald Barrow-Williams, Yannick Hourmand
  • Patent number: 10201693
    Abstract: A closed male luer includes a first connector having an upper end portion defining an axial recess, an inner circumferential slide track and several first ratchet teeth; and a second connector having lower end portion received in the axial recess of the first connector, having several second ratchet teeth selectively meshed with the first ratchet teeth such that rotation of the first connector in a first direction drives the second connector to rotate simultaneously in the first direction, wherein, after an upper end portion of the second connector is connected with a second member, rotation of the first connector in the first direction or rotation of the second connector in a second direction opposite to the first direction can break up the second ratchet teeth into pieces by the first ratchet teeth, hence permitting the second connector to rotate freely in 360° relative to the first connector.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: February 12, 2019
    Inventor: Hsi-Chin Tsai
  • Patent number: 10188798
    Abstract: The present invention relates to a medicament delivery device comprising a housing having opposite distal and proximal ends; a medicament container holder with a medicament container, disposed within the housing, wherein the container has a front opening with or for a delivery member for delivering the medicament therethrough and at least a movable stopper; a drive unit comprising a power source and a plunger rod, wherein said drive unit is arranged to be movable between a non-delivery state in which said power source is in a cocked state and a delivery state in which said power source acts on said plunger rod which in its turn acts on said stopper for delivering a dose of medicament from said medicament container; retaining means operably connected to said drive unit, and capable of holding said drive unit in its non-delivery state; and activation means operably connected to said retaining means, and capable of releasing said drive unit from its non-delivery state; wherein the device further comprises a deli
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: January 29, 2019
    Assignee: SHL GROUP AB
    Inventors: Lucio Giambattista, Antonio Bendek
  • Patent number: 10167311
    Abstract: Provided herein are boronic acid esters of boronic acid therapeutic agents, such as bortezomib. The boronic acid esters can be used to prepare liposomal formulations of boronic acid therapeutic agents with improved properties, such as enhanced stability. This disclosure, in one aspect, relates to compositions and methods of making and using the compositions.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: January 1, 2019
    Assignee: Ohio State Innovation Foundation
    Inventors: Michael Caligiuri, Robert Lee, Guido Marcucci
  • Patent number: 10124122
    Abstract: An attachment for a syringe or carpule includes a main body that encloses an interior space, into which a protrusion of the syringe or carpule can be inserted. The main body has a jacket surrounding the interior space, and includes an inner body connected to the jacket and arranged coaxially thereto. The inner body has an inner wall that, in the attached state of the attachment, contacts an outer surface of the protrusion or of the syringe or carpule by means of an interior surface facing the interior space. The inner wall of the inner body is connected to the jacket of the attachment by a number of webs. At least one web encloses an angle together with an imaginary radially extending line, the angle being greater than 0° and acute.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: November 13, 2018
    Assignee: VETTER PHARMA-FERTIGUNG GMBH & CO. KG
    Inventor: Jochen Zenker
  • Patent number: 10039883
    Abstract: The present invention is directed to a housing for a drug delivery device. The housing comprises an outer shell with an aperture, an insert received within the aperture and a clamp attached to the outer shell. The insert has at least one recess which is engaged by a lug of the clamp to retain the insert within the aperture of the outer shell. The invention is further directed to a pen-type injector having such a housing.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: August 7, 2018
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Thomas Frederick Osman
  • Patent number: 10039584
    Abstract: A system for use in combining two part preparations, such as bone cement, can include a chamber for intermixing liquid and powder components, a container, a vacuum channel, and a filter. The mixing chamber can be configured to hold a non-liquid, polymer powder component of a bone cement. The container can be configured to hold a liquid component of the bone cement. The vacuum channel can direct a partial vacuum to draw the liquid component from the container into the non-liquid component in the mixing chamber to intermix the components and to thereby provide a settable bone cement.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: August 7, 2018
    Assignee: DFine, Inc.
    Inventors: Christopher U. Phan, Andrew Kohm
  • Patent number: 9931470
    Abstract: An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: April 3, 2018
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Rajesh Kumar, Anil Namboodiripad