With Body Soluble, Antibactericidal Or Lubricating Materials On Conduit Patents (Class 604/265)
  • Patent number: 11324898
    Abstract: A portable insulin pump can utilize readings from a sensor incorporated into an infusion set used with the pump to deliver insulin to a patient to determine if the infusion set is or is likely to become dislodged from the patient. Readings from the sensor that are inconsistent with expected readings or a range of expected readings can indicate that the infusion set has become dislodged from the patient.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: May 10, 2022
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael Rosinko
  • Patent number: 11278649
    Abstract: Described herein are substrate coatings.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: March 22, 2022
    Assignee: MicroVention, Inc.
    Inventors: Aaron Baldwin, John Belletto, Wendy Beuthin
  • Patent number: 11267930
    Abstract: The disclosed technology provides thermoplastic polyurethane compositions having non-leaching antimicrobial properties while still maintaining good physical properties, methods of making the same, and articles, including medical devices, made from such compositions. The disclosed technology includes a process of making an antimicrobial polymer composition, where the process includes mixing an antimicrobial additive into a polymeric material; wherein said polymeric material comprises a polymeric backbone made up of urethane linkages derived from a polyisocyanate and a polyol; and wherein said mixing occurs under conditions that result in the breaking of a minority of said urethane bonds resulting in reactive isocyanate groups; and wherein two or more of said reactive isocyanate groups react with said antimicrobial additive to covalently bond said antimicrobial additive into the polymeric backbone of said polymeric material; resulting in an antimicrobial polymer composition.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: March 8, 2022
    Assignee: Lubrizol Advanced Materials, Inc.
    Inventors: Hua Zhang, Roger W. Day, Richard Woofter, Umit G. Makal, Kiara L. Smith
  • Patent number: 11229445
    Abstract: Clot removal from a patient's vessel, such as an artery, are described using aspiration and hydraulic forces supporting the removal process. Hydraulic forces can be generated by occluding the vessel distal to the clot and delivering liquid between the clot and the occlusive device. The aspiration catheter is positioned proximal to the clot. Catheters designed to facilitate the delivery of hydraulic forces can be based on single lumen designs or dual lumen designs. The catheters may have a fixed internal wire, or in some embodiments the catheters can ride over a wire with a valve/seal positioned to restrict flow into or out from the guide lumen such that the guide lumen can further function for balloon inflation and/or for infusion of liquid.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: January 25, 2022
    Assignee: MIVI Neuroscience, Inc.
    Inventor: Matthew F. Ogle
  • Patent number: 11147902
    Abstract: The invention provides cell-adherent polymeric coatings for articles, the coating including a synthetic, non-biodegradable polymer having a plurality of pendent amine groups, wherein the polymer is covalently immobilized on the article via latent reactive groups. The invention also provides methods for the long-term attachment of cells using the polymeric coatings.
    Type: Grant
    Filed: July 20, 2006
    Date of Patent: October 19, 2021
    Assignee: Surmodics, Inc.
    Inventors: Muhammad Lodhi, Tahmina Naqvi, Gary Oppermann
  • Patent number: 11141260
    Abstract: Bio-adhesive textured surfaces are described which allow implants to be localized within a living body. Hierarchical levels of texture on an implantable medical device, some capable of establishing a Wenzel state and others a Cassie state, are employed to interface with living structures to provide resistance to device migration. Since a gaseous state is traditionally required to establish a Cassie or Wenzel state, and gases do not remain long in living tissue, described are tissue/device interactions analogous to the above states with the component normally represented by a gas replaced by a bodily constituent, wherein separation of tissue constituents develops and an analogous Cassie, Wenzel or Cassie-Wenzel state evolves.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: October 12, 2021
    Assignee: BVW Holding AG
    Inventors: Lukas Bluecher, Michael Milbocker
  • Patent number: 11129736
    Abstract: A stent and method of making incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect element(s) across an intervening space. The polymeric connecting elements are designed to fold within the space between the outer diameter of the stent and the inner diameter of the stent.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: September 28, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Ryan D. Kariniemi, Jeffrey J. Kustusch, Mark J. Ulm
  • Patent number: 11116960
    Abstract: The invention relates to a catheter device, having a hollow catheter in the catheter cavity of which a moveable shaft is guided, having a proximal coupling device, for detachable coupling of a drive device, the coupling device having a coupling cavity which is open towards the drive device and into which the shaft or an extension of the shaft protrudes with a connection element for mechanical coupling of a motor shaft, the coupling cavity having a germ barrier for reducing the pathogenicity of pathogenic substances or microorganisms.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: September 14, 2021
    Assignee: ECP ENTWICKLUNGSGESELLSCHAFT MBH
    Inventors: Cornelia Simon, Julia Honselmann, Jens Baumgaertel, Reiner Liebing
  • Patent number: 11077234
    Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an ?-hydroxy acid, ?-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: August 3, 2021
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Craig Grossman, Gavri Grossman, Daniel Moros, Misagh Alipour, Jie Fang
  • Patent number: 11076977
    Abstract: An indwelling evacuator for feces, a stranding cage is disposed in a cylindrical main body, and a soft shaft is connected to the rear end of the stranding cage. Petaloid movable blades are hingedly connected to the front end of the cylindrical main body, and are in the shape of a bud when the petaloid movable blades are closed. A blocking ring is disposed on the outer wall of the cylindrical main body. A sliding ring member is disposed in the cylindrical main body to push the movable blades open to form an open space in the shape of a flower. The rear portion of the cylindrical main body is downward connected to a feces discharge hose. In use, the bud portion in the front end is inserted into the anus, and the blocking ring limits the insertion depth.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: August 3, 2021
    Assignee: JIANGSU HENGAI MEDICAL EQUIPMENT CO., LTD.
    Inventors: Hang He, Hanzhong He
  • Patent number: 11043303
    Abstract: The invention is a remote communication portal system and method of use, providing means of real-time, full-body video and audio while a variety of sensors or measurement devices read and communicate electronic data to one or all participants.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: June 22, 2021
    Assignee: My Virtual Exam, Inc.
    Inventor: Shawn Vernon
  • Patent number: 11000632
    Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 ?m or greater) which is very desirable for in vivo use.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: May 11, 2021
    Assignee: Surmodics, Inc.
    Inventors: David E. Babcock, Timothy M. Kloke, Joseph S. McGonigle
  • Patent number: 10980918
    Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 ?m or greater) which is very desirable for in vivo use.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: April 20, 2021
    Assignee: Surmodics, Inc.
    Inventors: David E. Babcock, Timothy M. Kloke, Joseph S. McGonigle, Nathan Lockwood, Bruce Jelle
  • Patent number: 10842148
    Abstract: Methods and formulations for antimicrobial and anti-biofouling coating comprising: a hollow round colloidal structure, comprising: an active polymer shell; and an active or inert core; wherein the active polymer shell comprises one and more polymers with antimicrobial and anti-biofouling activities selected from the group consisting of polyethylenimine (PEI), functionalized chitosan (CHI), polyquaternium, poly(diallyldimethylammonium chloride) (PDDA) and polyhexamethylene biguanide (PHMD); wherein the active or inert core contains one and more disinfectants, biocides, fragrances or inert solvent; and wherein the hollow round colloidal structure is stable for at least 3 months.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: November 24, 2020
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: King Lun Yeung, Hanrong Zhang, Ying Li, Awais Farid
  • Patent number: 10828272
    Abstract: The disclosure provides for means for a method to facilitate food intake and food retention in a mammal by applying a sufficient dose of a local anesthetic drug in the lumen of the pharyngeal-esophageal-gastric-duodenal tract before or during or after eating. The local anesthetic can be amethocaine, articaine, benzocaine, bupivacaine, chloroprocaine, cinchocaine, cyclomethycaine, dibucaine, diethocaine, etidocaine, larocaine, levobupivacaine, lidocaine, lignocaine, mepivacaine, novocaine, piperocaine, prilocaine, procaine, proparacaine, propoxycaine, QX-222, QX-314, ropivacaine, tetracaine, trimecaine, menthol, eugenol or a safe pharmaceutical formulations of tetrodotoxin, saxitoxin, or neosaxitoxin. The disclosure is useful for patients having problems with food intake or food retention.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: November 10, 2020
    Assignee: Chardon Group B.V.
    Inventors: Christophorus Louis Eduard Broekkamp, Bernardus Wijnand Mathijs Marie Peeters
  • Patent number: 10801649
    Abstract: The present disclosure relates to multi-layered tubings that are fuel resistant and resistant to delamination. In one aspect, the disclosure provides a length of tubing having an annular cross-section including an annular fluoropolymer layer formed from at least 75 wt % fluoropolymer (e.g., at least 75 wt % of a PVDF polymer), the fluoropolymer layer having an outer surface and an inner surface; and disposed about the fluoropolymer layer, an annular thermoplastic layer formed from at least 75 wt % thermoplastic (e.g., thermoplastic polyurethane, thermoplastic polyamide and/or thermoplastic polyester), the thermoplastic polyurethane layer having an inner surface in contact with the outer surface of the fluoropolymer layer and an outer surface, wherein the fluoropolymer layer is covalently bound to the thermoplastic polyurethane layer, for example, by electron beam treatment.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 13, 2020
    Assignee: Saint-Gobain Performance Plastics Corporation
    Inventors: James Ludlow, Kevin M. McCauley
  • Patent number: 10772996
    Abstract: A method of forming a silicone coating on an electrode carrier for use in cochlear implant systems includes dissolving silicone and dexamethasone in a solvent to form a solution, adding a non-solvent to the solvent, the non-solvent miscible with the silicone and the dexamethasone having a solubility in the non-solvent of below about 5 mg/ml, and curing the solution to form the silicone coating on the electrode carrier.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: September 15, 2020
    Assignee: MED-EL Elektromedizinische Geraete GmbH
    Inventor: Thomas Tritthart
  • Patent number: 10743865
    Abstract: An apparatus capable of and a corresponding method for subcuticular suturing of an incision in a single pass is provided. The apparatus includes a straight needle, a suture thread extending from a free end of the needle, and a grip couplable to or pre-attached to the needle. The grip is used for controlling, manipulating, and advancing the needle and its sharp end through the incision. The needle is generally long enough to pierce and bind both sides of the incision together without having to pull the entire needle and any slack in the suture thread through each piercing prior to proceeding to the next piercing. The needle holds the entire incision closed presets the entire path for the suture thread prior to pulling the suture thread through the incision to hold the incision closed.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: August 18, 2020
    Inventor: Sarbjeet S. Kumar
  • Patent number: 10669500
    Abstract: Described herein are coatings and formulations thereof for coating a substrate for use in producing a lubricious coating on a substrate surface that is to be inserted into the body lumen of a subject. Said coatings all contain an adhesion promoting coating formulation for applying to a substrate material that is formed from a polymeric adhesion promoter, a monomeric or polymeric crosslinking agent and a photoinitiator, where the polymeric adhesion promoter is a block copolymer comprising hydrophobic hydrophilic polymer blocks and/or a hydrophilic polymer comprising hydrophilic functional groups, where from 10% to 100% of the hydrophilic functional groups are capped with a hydrophobic functional group and the formulations thereof further contain a solvent to enable the coating to be applied to a substrate surface.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: June 2, 2020
    Assignees: JMEDTECH (XIAMEN) COATING TECHNOLOGY CO. LTD, JMEDTECH COATING TECHNOLOGIES PTE LTD
    Inventors: Jingnan Luo, Honglei Wang
  • Patent number: 10660622
    Abstract: Present invention solved the problem of complications occurred during transrectal prostate biopsy, mostly infectious and bleeding complications. Thus, the prostate biopsy needle according to the invention comprising a cannula (1), a pointed stylet (2), which is mounted slidably in the cannula (1), handles (3a, 3 b) for the biopsy gun, which are located on the back side of the needle. An inner surface (4) of the cannula (1) and/or an outer surface (5) of the cannula (1) and/or a surface of the stylet (2) is coated with at least one active layer (6) comprising a biologically active agent, wherein the active layer (6) preferably forms a biodegradable structure enabling controlled release of the biologically active agent.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: May 26, 2020
    Assignee: DEBN SP. Z O.O.
    Inventors: Marcin Sieczkowski, Artur Gibas, Marcin Matuszewski
  • Patent number: 10646700
    Abstract: The invention includes a shunt for at least partial implantation into a patient that includes an elongated conduit having at least one lumen therethrough, that includes a proximal end for receipt of bodily fluids for flow through the shunt and a distal end for discharge of the bodily fluids from the shunt, and a long term source of at least one occlusion resistant agent, wherein said at least a portion of the at least one occlusion resistant agent can permeate through at least a portion of the elongated conduit. The invention also includes kits and systems.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: May 12, 2020
    Assignee: MEDTRONICS PS MEDICAL, INC.
    Inventors: Paul V. Trescony, Edouard Koullick
  • Patent number: 10639452
    Abstract: A urethral catheter and its method of use to identify a patient's urethral anatomic course for the precise placement of a treatment element into the patient's prostate are provided. An echo-opaque urethral catheter including an echogenic material and a radio-opaque material in at least an image portion thereof is introduced into a urethra until its echogenic and radio-opaque image portion is generally aligned with a treatment site of the prostate. An image probe positioned relative to the treatment site is activated to obtain a real time image of the prostate and urethra by ultrasound or X-ray imaging. The echo-opaque urethral catheter includes an elongated flexible catheter, at least the image portion of which, is coated with, incorporates within or is enclosed by the echogenic and radio-opaque materials that enhance ultrasound and radio visualization.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: May 5, 2020
    Assignee: Best Medical International, Inc.
    Inventors: Luis Linares, Krishnan Suthanthiran, Manny R. Subramanian
  • Patent number: 10595837
    Abstract: The present disclosure relates to a method for vacuum expansion of a paste prior to freeze-drying said paste to achieve a dry paste composition which reconstitutes efficiently to form a flowable paste upon addition of an aqueous medium. The present disclosure further relates to a syringe for retaining a dry paste composition in a vacuum.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: March 24, 2020
    Assignee: Ferrosan Medical Devices A/S
    Inventors: Kristian Larsen, Michael Wrang Mortensen
  • Patent number: 10596302
    Abstract: Catheter tubing comprises: an elongate body comprising a base thermoplastic polyurethane; and a compounded thermoplastic polyurethane co-extruded with the base thermoplastic polyurethane to provide a section of catheter tubing discrete from the elongate body, the compounded thermoplastic polyurethane comprising a thermoplastic polyurethane and a radiopaque material, wherein the catheter tubing comprises a first elastic modulus under first conditions prior to entry into a patient; and wherein when exposed to second conditions comprising two or more in vivo stimuli for a duration of time the catheter tubing comprises a second elastic modulus that is not more than fifty percent of the first modulus.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: March 24, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Lisa Lim, Theresa Hermel-Davidock, Marc W. Weimer, Jonathan Karl Burkholz
  • Patent number: 10589063
    Abstract: An obturator can include antimicrobial features which assist in sterilizing or maintaining the sterility of fluid contained within a vascular access device while the device is not being used for infusion or other access to the patient's vasculature. These antimicrobial features include antimicrobial coatings applied to various surfaces of an obturator and antimicrobial components bonded or otherwise secured to an obturator. Various combinations of antimicrobial coatings and/or components can be used on an obturator as necessary to provide a desired amount of antimicrobial agents within a particular enclosed volume of a vascular access device.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: March 17, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Jonathan Karl Burkholz, Siddarth K. Shevgoor
  • Patent number: 10549051
    Abstract: A portable insulin pump can utilize readings from a sensor incorporated into an infusion set used with the pump to deliver insulin to a patient to determine if the infusion set is or is likely to become dislodged from the patient. Readings from the sensor that are inconsistent with expected readings or a range of expected readings can indicate that the infusion set has become dislodged from the patient.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: February 4, 2020
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael Rosinko
  • Patent number: 10532189
    Abstract: The invention relates to a drug-coated balloon catheter which has a catheter balloon mounted on its distal end and an expansion protection surrounding the same. The invention is characterized in that the catheter balloon is protected from premature expansion even under strong mechanical stress and in that the catheter balloon folds back more easily after dilation.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: January 14, 2020
    Assignee: Invatec Technology Center GmbH
    Inventors: Bruno Scheller, Ulrich Speck
  • Patent number: 10500388
    Abstract: A medical device material impregnated with a combination of antimicrobial agents, the combination of antimicrobial agents comprising a first antimicrobial agent, the first antimicrobial agent being triclosan and at least a second antimicrobial agent, wherein the combination of antimicrobial agents provides the device material with antimicrobial activity and inhibition of resistant microbial mutations for of the order of, or greater than, 80 days.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: December 10, 2019
    Assignee: THE UNIVERSITY OF NOTTINGHAM
    Inventor: Roger Bayston
  • Patent number: 10485667
    Abstract: Implants for prevention of cold welding, corrosion and tissue overgrowth on surfaces between medical implant components include a first medical implant component having a first implant contact surface, a second medical implant component having a second implant contact surface positionally interfacing with the first implant contact surface of the first medical implant and a separation coating material on at least one of the first implant contact surface and the second implant contact surface. Methods for prevention of cold welding and/or corrosion between and/or tissue/bone overgrowth on implant components and methods of scaling an interface between a first implant component and a second implant component in a prosthesis system are also disclosed.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: November 26, 2019
    Inventor: Lucas Anissian
  • Patent number: 10471277
    Abstract: Methods and apparatus for the inactivation of infectious agents in, on or around a catheter residing in a patient's body cavity. The method comprises a coupling adapter for facilitating the transmission of non-ultraviolet sterilizing electromagnetic radiation (EMR) substantially axially along an optical element into the catheter body. Through delivery of the sterilizing EMR to particular areas of highest infection, the present disclosure is able to inactivate the major sources of infection in catheters.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: November 12, 2019
    Assignee: Light Line Medical, Inc.
    Inventors: Nathaniel L. R. Rhodes, Adam E. Bracken, Martin de la Presa, Ahrash E. Poursaid, Ryan R. Coil, Mitchell D. Barneck, James P. Allen
  • Patent number: 10451643
    Abstract: The sample dispensing device sucks a liquid sample from a predetermined container and then discharges the sample to another container. The sample dispensing device includes a nozzle tip that sucks and holds the sample; a dispensing nozzle to which the nozzle tip can be detachably attached via a fitting part; a dispensing nozzle position control means that controls the position of the dispensing nozzle with respect to the predetermined container and the other container; a nozzle tip removing means that removes the nozzle tip from the dispensing nozzle; and a discarding box into which water can be supplied, and in which the nozzle tip removed from the dispensing nozzle is discarded. The nozzle tip is made of a water-soluble material, and after being removed from the dispensing nozzle by the nozzle tip removing means, the nozzle tip is dissolved by water in the discarding box.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: October 22, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kouichi Obari, Eiji Takaya, Takashi Otsu
  • Patent number: 10376618
    Abstract: A thoracic catheter system comprises a flexible thoracic catheter for inserting into a thoracic cavity of a human. A distal end of the thoracic catheter has a plurality of apertures. A proximate end of the thoracic catheter is designed to extend out of the thoracic cavity. A three way valve is one of fused with and removably attached to the proximal end of the thoracic catheter.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 13, 2019
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Alireza Hamidian Jahromi, David Hilton Ballard, Jeffery Adam Weisman, Horacio Ruben Vincent D'Agostino
  • Patent number: 10369256
    Abstract: A drug delivery balloon (10) has a drug thereon in the form of crystalline particles (12), the drug having a predetermined size distribution. Optionally marker particles (14, 16) are also provided. A texturized coating (18), a cap layer (20) and/or other methods may be used to increase particle loading capacity of the balloon.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: August 6, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Aiden Flanagan, Jan Weber, John Clarke
  • Patent number: 10314948
    Abstract: A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: June 11, 2019
    Assignee: The Spectranetics Coporation
    Inventors: Eugene T. Michal, Daniel J. Lerner, Matthew J. Pollman
  • Patent number: 10058679
    Abstract: An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: August 28, 2018
    Assignee: Venous Therapy Inc.
    Inventors: Anthony J. Comerota, Thomas J. Fogarty, Jonathan M. Olson, Richard A. Lotti
  • Patent number: 10022476
    Abstract: The present disclosure relates to medical catheters, tubes, and other medical devices, systems, and methods. The catheter, tube, or other medical device is capable of releasing drugs for extended periods of time. Drugs can be loaded into the wall thereof with a loading solution. The drug in the wall of the device and in the loading solution can be in dynamic equilibrium, yielding stable and easy-to-manufacture products.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: July 17, 2018
    Assignee: Medcatheters, Inc.
    Inventor: Jie Zhang
  • Patent number: 9999754
    Abstract: Provided are methods, systems, and kits of properly delivering a biodegradable stent into a body lumen of a subject. More particularly, provided are methods, systems, and kits of properly delivering a biodegradable ureteral stent into the kidney and the bladder of a subject. Even more particularly, provided are methods, systems, and kits of properly delivering a chitosan based stent into a body lumen of a subject. Even more particularly, provided are methods, systems, and kits of properly delivering a chitosan based ureteral stent into the kidney and the bladder of a subject.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: June 19, 2018
    Assignee: Gyrus ACMI, Inc.
    Inventor: Hui Tang
  • Patent number: 9867907
    Abstract: A catheter assembly includes at least one self-lubricated part formed from a mixture including a polymer and lubricant. The polymer has a functional group that can react with the functional group of the lubricant. The suitably functionalized lubricant provides for a low coefficient of friction surface for easier and less traumatic insertion and withdrawal of the catheter into and from body cavities.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: January 16, 2018
    Assignee: Hollister Incorporated
    Inventors: Shamsedin Rostami, Joel D. Shutt
  • Patent number: 9861799
    Abstract: A shunt for at least partial implantation into a patient that includes an elongated conduit having at least one lumen therethrough and a second lumen concentric about the first lumen along at least part of the first lumen, that includes a proximal end for receipt of bodily fluids for flow through the shunt and a distal end for discharge of the bodily fluids from the shunt, and a long term source of at least one occlusion resistant agent, wherein said at least a portion of the at least one occlusion resistant agent can permeate through at least a portion of the elongated conduit. The invention also includes kits and systems.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: January 9, 2018
    Assignee: MEDTRONIC PS MEDICAL, INC.
    Inventors: Paul V. Trescony, Edouard Koullick
  • Patent number: 9849276
    Abstract: A system, method, and article for delivering an antimicrobial agent into the lumen of a trans-dermal catheter are disclosed. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter, and the elongate member containing an antimicrobial. In the alternative an antimicrobial agent can be placed on an interior surface of a retaining ring.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: December 26, 2017
    Assignee: Pursuit Vascular, Inc.
    Inventors: Robert J. Ziebol, Keith J. Modert
  • Patent number: 9839769
    Abstract: An expandable sheath assembly includes a support body extending from a proximal end to a distal end. A guide rod is interconnected to the support body and extends between the ends along an axis. A dilator extends from the guide rod for insertion into a body vessel, and a hub is releasable connected to the distal end of the support body. A distal sheath overlays the dilator, and a hemostatic valve is slidably disposed along the axis. A proximal sheath extends from the hemostatic valve and is disposed in surrounding and coaxial relationship with the guide rod. The proximal sheath is concurrently slidable with the hemostatic valve along axis to advance the proximal sheath through the hub and interleave the proximal sheath between the dilator and the distal sheath for lifting the distal sheath from the dilator and effectuating an expansion of the body vessel.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: December 12, 2017
    Assignee: FREUDENBERG MEDICAL, LLC
    Inventors: Greg Furnish, Anthony Appling, Simon Furnish, Asela Indaka Gunasekara, Ben Morris
  • Patent number: 9814865
    Abstract: A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: November 14, 2017
    Assignee: Cook Medical Technologies LLC
    Inventors: Brian L. Bates, Anthony O. Ragheb, Joseph M. Stewart, IV, William J. Bourdeau, Brian D. Choules, James D. Purdy, Neal E. Fearnot
  • Patent number: 9789279
    Abstract: An obturator can include antimicrobial features which assist in sterilizing or maintaining the sterility of fluid contained within a vascular access device while the device is not being used for infusion or other access to the patient's vasculature. These antimicrobial features include antimicrobial coatings applied to various surfaces of an obturator and antimicrobial components bonded or otherwise secured to an obturator. Various combinations of antimicrobial coatings and/or components can be used on an obturator as necessary to provide a desired amount of antimicrobial agents within a particular enclosed volume of a vascular access device.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: October 17, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Jonathan Karl Burkholz, Siddarth K. Shevgoor
  • Patent number: 9782423
    Abstract: The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic dispersant or a mucolytic anti-adhesive agent, which are useful in relation to the prevention and treatment of bacterial infections.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: October 10, 2017
    Assignee: Novabiotics Limited
    Inventors: Deborah O'Neil, Cedric Charrier
  • Patent number: 9744348
    Abstract: Embodiments of the invention are related to leads with topographic surface features and related methods, amongst other things. In an embodiment, the invention includes an implantable lead including a lead body having a proximal end and a distal end, the lead body including an outer layer defining a lumen, the lead body further including a first electrical conductor disposed within the lumen of the outer layer. The implantable lead can further include a first electrode coupled to the lead body, the electrode in electrical communication with the first electrical conductor. The implantable lead can also include a cellular modulation segment on the external surface of the lead body, the cellular modulation segment comprising topographic surface features configured to modulate cellular responses. Other embodiments are also included herein.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: August 29, 2017
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Craig M. Stolen, Mark J. Schwartz, John D. Foley, Lili Liu
  • Patent number: 9738785
    Abstract: A plastic molding composition includes a powder, gelatin, a polar solvent, and an adhesion reducer. The powder contains at least one of a ceramic particle and a metal particle. The adhesion reducer reduces adhesion of the gelatin so that a molded product, which is molded from the composition with a molding die, is removed from the molding die without being broken. The adhesion reducer is a water-soluble or water-dispersible compound. The adhesion reducer has a HLB value, calculated by Griffin's method, ranging from 10 to 20.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: August 22, 2017
    Assignee: DENSO CORPORATION
    Inventors: Yasuki Aoi, Mayumi Ozeki
  • Patent number: 9737423
    Abstract: A stent able to minimize occurrences of strain and stress concentration in a drug coat layer upon expansive deformation of the stent in a radial direction to avoid the possibility of the drug separating from the stent, includes a stent body and a drug coating layer coated on the outside surface of the stent body so that the thickness of the drug coating layer gradually decreases toward a bent portion of the stent.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: August 22, 2017
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Kazuhiro Maruyama, Noboru Saito, Hiroki Goto
  • Patent number: 9701848
    Abstract: The invention relates to the production and use of novel bioactive devices and metallic coatings for example for sterilizing, disinfecting, and decontaminating water or aqueous solutions. The known oligodynamic effect of silver for reducing the amount of germs is thereby improved and increased by combining silver with ruthenium and a vitamin or derivative thereof. The novel properties of these bioactive metal surfaces lead to faster and more efficient killing of microorganisms. Simultaneously, these novel bioactive metal surfaces prevent infestation by microorganisms and attachment or permanent deposition of problematic biomolecules such as for example DNA, RNA, or proteins. A self-cleaning surface is thus obtained, which very quickly and efficiently and over extended periods of time sterilizes water and aqueous solutions when they come in contact with said surface.
    Type: Grant
    Filed: October 2, 2007
    Date of Patent: July 11, 2017
    Assignee: AGXX INTELLECTUAL PROPERTY HOLDING GMBH
    Inventors: Uwe Landau, Thomas Lisowsky, Karlheinz Esser, Klaus-Dieter Mehler
  • Patent number: 9669149
    Abstract: Splitable-tip catheters are disclosed with bioresorbable adhesive to provide spatial separation of distal tip elements during use. The invention can be particularly useful in hemodialysis applications where it is desirable to separate blood extraction and return lumens. The adhesive facilitates insertion of the distal end of the catheter as an assembly, e.g., into a blood vessel using a single guidewire, while the bioresorbable nature of the adhesive allows the tip elements to separate in vivo.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: June 6, 2017
    Assignee: Bard Access Systems, Inc.
    Inventor: Paramjith Anand
  • Patent number: RE48426
    Abstract: A vapor hydrated packaged catheter assembly and method of manufacturing and distributing same includes a gas impermeable package housing a catheter within a catheter-receiving cavity. The catheter assembly has a hydrophilic coating applied to at least a portion of the outer surface of a catheter tube or shaft which may be surrounded by a sleeve to provide a no-touch, sure grip feature. The catheter assembly is disposed within the catheter receiving cavity of the package together with a limited amount of a vapor donating liquid provided as a source of vapor to activate the hydrophilic coating. The amount of vapor donating liquid is less than the amount that would otherwise be sufficient to cause a spill hazard. It may be loose liquid as a desired percentage of the volume of a tube-receiving portion of the catheter receiving cavity of the package, or it may be contained in a liquid sequestering element.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: February 9, 2021
    Assignee: Hollister Incorporated
    Inventors: Michael Murray, Thomas H. Gilman, Sean Sweeney, Martin P. Creaven