With Body Soluble, Antibactericidal Or Lubricating Materials On Conduit Patents (Class 604/265)
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Publication number: 20140276599Abstract: An endoluminal device comprises a tubular member and a reinforcement member that is separable from, or together with, a wall of the tubular member, and removable in-situ.Type: ApplicationFiled: February 21, 2014Publication date: September 18, 2014Applicant: W. L. Gore & Associates, Inc.Inventors: Edward H. Cully, Jeffrey B. Duncan, Brian C. Martonik
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Publication number: 20140276412Abstract: Catheter including an inner tubular member having a proximal end portion, a distal end portion and an exterior surface. The inner tubular member further has a guidewire lumen defined therein. An outer tubular member is movable relative to the inner tubular member, the outer tubular member has a proximal end, a distal end and an interior surface directed toward the exterior surface of the inner tubular member. A movable tubular structure is disposed between the outer tubular member and the inner tubular member. The movable tubular structure includes a body member having an outer surface with a recess defined therein. The outer tubular member is received within the recess to form a trough along a portion of an exterior surface of the outer tubular member. The trough has a filler disposed therein to couple the outer tubular member to the body member of the movable tubular structure.Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Inventors: Daniel H. Shumer, Nianjiong Joan Bei, Marc Gianotti, Ana Montano-Morse
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Patent number: 8828040Abstract: A device for the transfer of radiopaque material within the body comprises a valvuloplasty or other balloon coated with the radiopaque material. The balloon is inflated in the aortic valve for marking the site of an aortic annulus to enable accurate placement of prosthetic valves under fluoroscopic imaging.Type: GrantFiled: July 6, 2010Date of Patent: September 9, 2014Inventor: Thomas G. Goff
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Publication number: 20140249489Abstract: A sterilized ready-to-use catheter includes a package, a catheter having a hydrophilic coating, and an aqueous solution in contact with the catheter inside of the package.Type: ApplicationFiled: May 13, 2014Publication date: September 4, 2014Applicant: Coloplast A/SInventor: Niels Joergen Madsen
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Patent number: 8821455Abstract: An antimicrobial coating applied to a transdermal surface of a catheter device. An antimicrobial coating applied to catheter device such that when the catheter device is fully inserted, the antimicrobial coating is interposed between the catheter device and the dermal layers of the patient.Type: GrantFiled: July 7, 2010Date of Patent: September 2, 2014Assignee: Becton, Dickinson and CompanyInventors: Jonathan Karl Burkholz, Minh Quang Hoang
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Patent number: 8808275Abstract: A catheter assembly includes a catheter having on at least part of its surface a hydrophilic surface layer; a wetting fluid pouch including first and second layers of flexible material joined by a seal to form a sealed closure accommodating the wetting fluid; a receptacle forming a cavity for accommodation of the catheter and the wetting fluid pouch. The wetting fluid pouch is openable by compression of the wetting fluid pouch, thereby enabling the wetting fluid to be discharged into the receptacle. At least one of the first and second layers of the wetting fluid pouch extends beyond the seal of the sealed closure to form an attachment area outside the sealed closure, the wetting fluid pouch is attached to an inner surface of the receptacle, and the attachment being provided solely between the receptacle and the attachment area.Type: GrantFiled: May 24, 2011Date of Patent: August 19, 2014Assignee: Astra Tech AbInventor: Evelina Gustavsson
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Patent number: 8808272Abstract: A modified medical device for delivery of a pharmaceutically active material is described. The present inventors have found that many conventional medical devices contain a metallic or polymeric component that comes into contact with a pharmaceutically active material during use, and that the contact substantially reduce the pharmaceutical effectiveness of the pharmaceutically active material. The invention described herein concerns various modifications to the metallic or polymeric component that are effective to diminish such a substantial reduction in pharmaceutical effectiveness.Type: GrantFiled: June 12, 2006Date of Patent: August 19, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: James Barry, Maria Palasis, Louis Ellis, Timothy Mickley, Brian Berg
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Patent number: 8802603Abstract: This invention relates to medical articles, such as a syringe assemblies, including a substrate having a coating on a surface thereof, the coating including: (1) at least one organopolysiloxane and (2) a deposition product applied to the at least one organopolysiloxane by plasma-enhanced chemical vapor deposition of a composition including at least one monomer selected from the group consisting of N-vinyl pyrrolidone, vinyl acetate, ethylene oxide, alkyl acrylate, alkyl methacrylate, acrylamide, acrylic acid, and mixtures thereof, and methods of making and using the same.Type: GrantFiled: June 16, 2011Date of Patent: August 12, 2014Assignee: Becton, Dickinson and CompanyInventors: Ajit Joseph M. D'Souza, David B. Montgomery
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Publication number: 20140200523Abstract: An antimicrobial composition, generally comprising a biocidal agent, such as chlorhexidine gluconate, a lubricant, such as a modified siloxane, and a solvent, such as an alcohol and/or water. The biocidal agent acts as a highly effective biocide while the lubricant reduces friction between various components of a medical device during assembly. The antimicrobial composition may be applied to an internal component of the medical device prior to assembly. The process of assembling the medical device results in antimicrobial composition being distributed to various internal structures and geometries of the medical device as the coated, internal component is assembled into the interior of the medical device. Air is then used to further distribute excess antimicrobial agent to the remaining surfaces downstream from the installed, internal component. In some embodiments, additional air is passed through the assembled medical device to assist in removing the carrier solvent from the medical device via evaporation.Type: ApplicationFiled: March 31, 2014Publication date: July 17, 2014Applicant: Becton, Dicksinson and CompanyInventors: Jonathan Karl Burkholz, Minh Quang Hoang
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Publication number: 20140180220Abstract: An article having a nonfouling surface thereon is comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; and (c) a polymer layer formed on the linking layer, preferably by the process of surface-initiated polymerization of monomeric units thereon, with each of the monomeric units comprising a monomer core group having at least one protein-resistant head group coupled thereto, to thereby form a brush molecule on the surface portion. The brush molecule comprising a stem formed from the polymerization of the monomer core groups, and a plurality of branches formed from the hydrophilic head group projecting from the stem. Methods of making and using such articles, are also described.Type: ApplicationFiled: July 16, 2013Publication date: June 26, 2014Inventors: Ashutosh Chilkoti, Hongwei Ma
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Publication number: 20140180221Abstract: The invention relates to an article comprising a coating, which coating comprises at least two layers, of which the inner layer is a primer layer, comprising a supporting network comprising a supporting polymer, and the outer layer is a functional layer comprising a multifunctional polymerizable compound.Type: ApplicationFiled: December 13, 2013Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Aylvin Jorge Angelo Athanasius DIAS, Edith Elisabeth M. VAN DEN BOSCH, Peter BRUIN, Marnix ROOIJMANS, Rudolfus Antonius Theodorus Maria VAN BENTHEM
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Patent number: 8758847Abstract: A medical device includes a proximal end, a distal end sized for introduction into a body lumen, and a lumen extending between the proximal and distal ends. The tubular device includes an inner liner including a coating on an inner surface thereof, a reinforcing layer surrounding at least a portion of the liner; and an outer layer surrounding the reinforcing layer and inner liner. The liner and outer layer may include multiple sections having different properties than one another, adjacent sections attached together by seams, which may be offset from one another. Apparatus and methods for making tubular devices with coated liners are also provided.Type: GrantFiled: August 31, 2009Date of Patent: June 24, 2014Assignee: Aust Development, LLCInventors: Stephen Arie Leeflang, Christian Scott Eversull
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Patent number: 8748544Abstract: A medical appliance including a slidable coating layer moves in contact with an inner surface of a medical member or that of a lumen. The medical appliance has the slidable coating layer formed at a part thereof which contacts the medical member or the lumen. The slidable coating layer is formed of a composition containing a solventless-type hardening silicone-based resin.Type: GrantFiled: September 30, 2013Date of Patent: June 10, 2014Assignee: Terumo Kabushiki KaishaInventors: Yoshihiko Abe, Eiji Watanabe
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Patent number: 8742032Abstract: A medical appliance having a slidable coating layer that moves in contact with an inner surface of a medical member or that of a lumen and has the slidable coating layer formed at a part thereof which contacts the medical member or the lumen. The slidable coating layer is formed of a composition which does not contain solid fine particles and contains a silicone-based resin which is a product of an addition reaction between silicone having a vinyl group and silicone having a hydrogen group bonded to a silicon atom.Type: GrantFiled: September 27, 2012Date of Patent: June 3, 2014Assignee: Terumo Kabushiki KaishaInventors: Yoshihiko Abe, Eiji Watanabe
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Patent number: 8740863Abstract: A catheter assembly is provided comprising a catheter (3;530;630;730) including a catheter tube (32) and a connector (31;531) arranged in one end of the catheter tube. The catheter is preferably a urinary, hydrophilic catheter. Further, the assembly comprises a catheter receptacle (2;520;620;720) for accommodation of at least the catheter tube, wherein the receptacle is provided with an opening (22;622;722), said opening being connected to and closed by the connector (31;531) of the catheter. A method for producing such a catheter assembly is also provided.Type: GrantFiled: April 29, 2003Date of Patent: June 3, 2014Assignee: Astra Tech ABInventors: Daniel Nestenborg, Andrea Schmid
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Patent number: 8720685Abstract: A vapor hydrated packaged catheter assembly and method of manufacturing and distributing same includes a gas impermeable package housing a catheter within a catheter-receiving cavity. The catheter assembly has a hydrophilic coating applied to at least a portion of the outer surface of a catheter tube or shaft which may be surrounded by a sleeve to provide a no-touch, sure grip feature. The catheter assembly is disposed within the catheter receiving cavity of the package together with a limited amount of a vapor donating liquid provided as a source of vapor to activate the hydrophilic coating. The amount of vapor donating liquid is less than the amount that would otherwise be sufficient to cause a spill hazard. It may be loose liquid as a desired percentage of the volume of a tube-receiving portion of the catheter receiving cavity of the package, or it may be contained in a liquid sequestering element.Type: GrantFiled: May 25, 2012Date of Patent: May 13, 2014Assignee: Hollister IncorporatedInventors: Michael Murray, Thomas H. Gilman, Sean Sweeney, Martin P. Creaven
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Patent number: 8721627Abstract: A disinfecting and pre-opening device is disclosed for use with a female needleless connector. The disinfecting and pre-opening device includes a housing comprising a chamber having a distal opening and configured to fit over the female needleless connector, and an elongated finger attached to the housing and disposed within the chamber such that the elongated finger opens the fluid path through the female needleless connector when the distal opening of the disinfecting and pre-opening device is placed proximally adjacent to the septum and the disinfecting and pre-opening device is advanced in the distal direction.Type: GrantFiled: July 22, 2010Date of Patent: May 13, 2014Assignee: CareFusion 303, Inc.Inventor: Robert S. Alpert
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Patent number: 8708978Abstract: An article to be inserted in a human or animal body cavity, use of the article and preparation thereof. The article has a biologically inhibiting arrangement of electrically connected electrode materials in direct contact with each other on one or more surfaces of the article. The arrangement includes as electrode materials a metallic anode material and a cathode material, where the potential of the cathode material is higher than the potential of the anode material. The cathode material is an electrically conductive material selected among certain non-metallic materials. The arrangement provided on the article releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with a body fluid.Type: GrantFiled: March 17, 2006Date of Patent: April 29, 2014Assignee: Impactcare ApSInventors: Per Møller, Anette Alsted Rasmussen
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Publication number: 20140114260Abstract: The present invention provides a medical tube mainly comprising a thermoplastic resin wherein the surface contacting the blood has been subjected to a heparinizing treatment and wherein quality defect due to whitening and oil defect is reduced. According to the present invention, there is provided a medical tube wherein an antithrombotic material is coated on the inner surface of a tube prepared by a melt extrusion molding of a composition comprising a thermoplastic resin and a plasticizer, characterized in that the difference (?L) between the brightness of the medical tube before coating and the brightness of the medical tube after coating measured in accordance with JIS Z 8722 is 1 or less.Type: ApplicationFiled: August 8, 2012Publication date: April 24, 2014Applicant: TOYOBO CO., LTD.Inventors: Yuta Kawakatsu, Shigeo Tsuchiya, Masaharu Yamada, Tomoya Ohashi, Wataru Takahama
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Patent number: 8703229Abstract: A method of making catheters is disclosed in which the wall of the catheter has a porous structure for carrying additional agents, such as therapeutic agents, diagnostic agents and/or device enhancements. The method includes applying a base polymer material and an inert material over the outer surface of a core, and curing or consolidating the base polymer material to form a catheter having a porous polymer layer with the inert material contained within the pores thereof. The inert material can be applied with the base polymer material or in a separate step after the base polymer material has been partially cured or consolidated to form the porous polymer layer. Additional agents can be mixed with the inert material before it is applied to the catheter, or can be applied to the porous polymer layer of the catheter in a separate step after the inert material is removed therefrom.Type: GrantFiled: April 13, 2010Date of Patent: April 22, 2014Assignee: Volcano CorporationInventor: Matt D. Pursley
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Patent number: 8663272Abstract: Devices and methods for sealing an opening in a blood vessel are disclosed. A device can include: an elongate, tubular non-stick outer sheath, the non-stick outer sheath having a distal end that is insertable into a vessel of a patient through the opening in the vessel wall, and having a proximal end remaining outside the patient; an elongate, tubular non-stick inner sheath disposed within the non-stick outer sheath; and an elongate, tubular adhesive film disposed between the non-stick outer sheath and the non-stick inner sheath, the adhesive film having both inward-facing and outward-facing adhesive surfaces and being supportable by the non-stick inner sheath during insertion into the vessel of the patient.Type: GrantFiled: October 5, 2011Date of Patent: March 4, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Roger Hastings, Michael Pikus
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Patent number: 8657792Abstract: A medicine delivering tube capable of transporting fluid from an existing medicine dispensing unit to the patient preferably includes a protective sleeve concentrically positioned about the medicine delivering tube such that a lubricant receiving zone is intercalated between an outer surface of the medicine delivering tube and an inner surface of the protective sleeve. The protective sleeve preferably includes a plurality of holes spaced along a major surface area of the protective sleeve. A lubricant dispensing unit is in fluid communication with the protective sleeve thereby injecting lubricant into the lubricant receiving zone for reducing friction between the outer surface of the medicine delivering tube and the inner surface of the protective sleeve. In this manner, upon applying an external force to the protective sleeve, the lubricant is caused to egress the protective sleeve via the holes thereby reducing friction along an outer surface of the protective sleeve.Type: GrantFiled: December 27, 2011Date of Patent: February 25, 2014Inventor: Kathy Hintze
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Patent number: 8652200Abstract: A medical device comprising a plurality of capsules, and a method of administering therapeutic agent to a patient using the same. The capsules further comprise a therapeutic agent and a multilayer polyelectrolyte shell. The medical device is adapted to apply a pressure to the capsules that is greater than or equal to the critical pressure of at least a portion of the capsules, such that therapeutic agent is released from the capsules.Type: GrantFiled: April 10, 2008Date of Patent: February 18, 2014Assignee: Boston Scientific Scimed, Inc.Inventor: Jan Weber
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Patent number: 8647326Abstract: One or more caps can be used to cover and sterilize one or more separated medical connectors. A pair of caps can be connected to each other and sealed when in a pre-use state. The paired caps can be unsealed so as to permit connection to the medical connectors.Type: GrantFiled: October 30, 2009Date of Patent: February 11, 2014Assignee: Catheter Connections, Inc.Inventors: Donald D. Solomon, F. Mark Ferguson, Robert Hitchcock, Steven Bandis, James Mercer, Michael Howlett
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Patent number: 8647718Abstract: A lubricant surface coating having good lubricity and high durability, comprising (A) an urethane polymer layer comprising (a) 40 to 80% by weight of at least one component selected from an aromatic diisocyanate, an aliphatic diisocyanate and an alicyclic diisocyanate and (b) 20 to 60% by weight of a polyol having at least trifunctionality and (B) a hydrophilic polymer layer provided as the outer layer for the urethane polymer layer which comprises a polyalkylene glycol and/or a monomethoxypolyalkylene glycol; and a medical device having the surface coating.Type: GrantFiled: March 8, 2006Date of Patent: February 11, 2014Assignee: Kaneka CorporationInventors: Yoichi Matsumura, Shuhei Taniguchi
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Patent number: 8640725Abstract: A connector for transferring fluid and method therefor. The connector may have a first port, a second port, and a third port which may be coupled together at a main channel with a first valve element therein controlling fluid flow through the first port. The first valve element is supported by a valve element support positioned between the first port and the third port, and the second port joins the main channel to provide a fluid path around the first valve element and through the third port.Type: GrantFiled: March 3, 2011Date of Patent: February 4, 2014Assignee: CareFusion 303, Inc.Inventors: Tim L. Truitt, Alex Truman Mazza, Cliff Colwell Corona
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Publication number: 20140031764Abstract: A medical appliance including a slidable coating layer moves in contact with an inner surface of a medical member or that of a lumen. The medical appliance has the slidable coating layer formed at a part thereof which contacts the medical member or the lumen. The slidable coating layer is formed of a composition containing a solventless-type hardening silicone-based resin.Type: ApplicationFiled: September 30, 2013Publication date: January 30, 2014Applicant: TERUMO KABUSHIKI KAISHAInventors: Yoshihiko ABE, Eiji Watanabe
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Publication number: 20130345636Abstract: Apparatuses and methods for administering a hemostatic agent to the tissue surrounding an opening in a body lumen are disclosed. The apparatus can include a tissue-contacting region and an optional body lumen-penetrating region. At least one hemostatic agent is included as a component of a coating over and/or a mixture with the material of at least a portion of the tissue-contacting region.Type: ApplicationFiled: August 26, 2013Publication date: December 26, 2013Applicant: Abbott LaboratoriesInventors: Wouter E. Roorda, Stefan Richter
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Publication number: 20130345645Abstract: A medical device for use in connection with a connector of an indwelling line for cleansing a surface of a septum of the connector is provided. The medical device includes a housing including a proximal portion defining a cavity containing a quantity of microbial reducing agent, a distal portion defining a cavity for selective coupling with the connector of the indwelling line, and a partition separating the proximal and distal cavities, wherein the proximal and distal cavities are in fluid communication with one another; and a deformable member overlying an end of the proximal portion for maintaining the microbial reducing agent within the proximal cavity thereof. The microbial reducing agent being dispensable into the distal cavity, at least when the medical device is connected to the connector of the indwelling line, to awash a surface of the connector of the indwelling line and reduce microbes present thereon.Type: ApplicationFiled: August 1, 2013Publication date: December 26, 2013Applicant: Covidien LPInventor: Todd M. Chelak
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Patent number: 8591486Abstract: Systems and methods are provided for moving fluids from a patient to a canister and lowering or eliminating the bio-burden of the canister. In one instance, a method for removing fluids from a patient includes using reduced pressure to remove fluids from a patient, delivering the fluids into a reduced-pressure conduit and into a fluid reservoir, exposing the fluids removed from the patient to a UV light source to kill pathogens to create disposable fluids, and disposing of the disposable fluids. Other systems, devices, and methods are presented.Type: GrantFiled: November 9, 2011Date of Patent: November 26, 2013Assignee: KCI Licensing, Inc.Inventors: Christopher Brian Locke, Timothy Mark Robinson
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Publication number: 20130310772Abstract: The present invention aims to provide a surface modification method for a rubber vulcanizate or a thermoplastic elastomer, which can impart excellent sliding properties and durability against repeated sliding motion and can allow the surface to maintain the sealing properties, without using expensive self-lubricating plastics. The present invention relates to a surface modification method for modifying a rubber vulcanizate or a thermoplastic elastomer as an object to be modified, the method including: Step 1 of allowing a photopolymerization initiator to be adsorbed on a surface of the object to be modified; and Step 2 of radical polymerizing monomers, starting from the adsorbed photopolymerization initiator, by irradiation with UV light at a wavelength of 300 nm to 400 nm to grow polymer chains on the surface of the object to be modified.Type: ApplicationFiled: February 25, 2013Publication date: November 21, 2013Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Yasuhisa MINAGAWA
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Patent number: 8574490Abstract: Methods and apparatus for preventing patient bloodstream infection by microorganisms during administration of various medications or fluids through IV lines. In particular, the invention reduces contamination of IV lines, connecters, stopcock valves, manifolds, ports, etc. by means of irradiation by violet and/or blue light. Each embodiment comprises a source of violet and/or blue light and an optical element optically coupled to that light source for shaping the radiation pattern of the light emitted by the light source. Preferably, a light-emitting diode or a laser diode that emits light in the desired wavelength can be used. The optical element, optically coupled to the light source, is embedded or installed in or attached to a component of an IV set, the emitted light being directed to a “point of entry” or any other stagnation point of an IV set.Type: GrantFiled: March 31, 2010Date of Patent: November 5, 2013Assignee: Bactriblue, Ltd.Inventors: Eyal Haytman, Assaf Deutsch, Eliahu Pewzner
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Publication number: 20130289498Abstract: Disclosed is a catheter and a method for making a catheter. The catheter has a proximal end and a distal end, and includes from the distal end towards the proximal end a distal section, an intermediate section and a proximal section, wherein the intermediate section is provided with a coating such that the intermediate section experiences less friction in use than the distal section and the proximal section.Type: ApplicationFiled: April 30, 2012Publication date: October 31, 2013Applicant: PENDRACARE INTERNATIONAL B.V.Inventor: Gjalt BOSMA
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Patent number: 8568373Abstract: An elongate member housing tool assembly includes a distal end side tubular member disposed on the distal end side and a proximal end side tubular member disposed on the proximal end side, which accommodate an elongate member, and a liquid inlet port to which a liquid supplying tool for supplying liquid into the distal end side tubular member is removably connected and which is provided on the distal end side tubular member. The distal end side tubular member and the proximal end side tubular member are wound spirally, and the proximal end of the distal end side tubular member and the distal end of the proximal end side tubular member are disposed in a spaced relationship from each other. A distal portion of the guide wire is accommodated in the distal end side tubular member, except possibly the most distal portion of the elongate member.Type: GrantFiled: July 29, 2011Date of Patent: October 29, 2013Assignee: Terumo Kabushiki KaishaInventors: Junko Kuniyasu, Junichi Kobayashi, Yasushi Kinoshita, Tadashi Kousai
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Publication number: 20130274686Abstract: Systems, methods, and articles for providing an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition on surface a cap element transfers antimicrobial to the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial.Type: ApplicationFiled: June 11, 2013Publication date: October 17, 2013Inventors: Robert J. Ziebol, Keith J. Modert
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Patent number: 8551058Abstract: Devices are provided herein for translumenal access to a treatment site within a body cavity. In general, the devices include an elongate sleeve configured to provide access to a treatment site wherein various portions of the sleeve are associated with an anti-microbial agent. Additionally, the anti-microbial agent(s) can be disposed within a housing and/or inner lumen of the sleeve such that surgical instruments passing therethrough can be sterilized en route to and/or being withdrawn from the treatment site. Additionally, various methods are also provided herein for maintaining the sterility of a treatment site.Type: GrantFiled: July 10, 2007Date of Patent: October 8, 2013Assignee: Ethicon Endo-Surgery, Inc.Inventors: John P. Measamer, Michael S. Cropper
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Publication number: 20130245570Abstract: Progesterone-containing compositions and devices that can maintain opening of a body passageway are described. One aspect of the invention provides a therapeutically effective (e.g., relaxative, anti-oxidative, anti-restenotic, anti-angiogenic, anti-neoplastic, anti-cancerous, anti-precancerous and/or anti-thrombotic) composition or formulation containing progesterone and optionally vitamin E and/or conjugated linoleic acid. Another aspect of the invention provides a drug eluting device, such as a drug eluting stent, with at least one coating layer comprising a progesterone composition that can minimize or eliminate inflammation, thrombosis, restenosis, neo-intimal hyperplasia, rupturing of vulnerable plaque, and/or other effects related to device implantation, treatment, or interaction. Other aspects of the invention provide for methods of using such compositions, formulations, and devices.Type: ApplicationFiled: May 3, 2013Publication date: September 19, 2013Inventor: Gregg A. Jackson
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Publication number: 20130245569Abstract: An implantable drug delivery accessory is described. A middle ear guide member has a hollow interior enclosed by a non-permeable outer surface. A proximal end of the middle ear guide member is fixed to the tympanic membrane of an implanted patient. A distal end of the middle ear guide member penetrates through a fluid-tight sealed opening into the inner ear. An inner ear holding member has a proximal end connected to the distal end of the middle ear guide member at the sealed opening and a closed distal end terminating the inner ear holding member some predetermined distance within the cochlea. A hollow interior of the inner ear holding member contains a replaceable drug delivery member which stores a therapeutic drug. A semi-permeable outer surface of the inner ear holding member is connected to a cochlear implant electrode and adapted to release therapeutic drug from the hollow interior into adjacent tissue.Type: ApplicationFiled: March 5, 2013Publication date: September 19, 2013Applicant: MED-EL ELEKTROMEDIZINISCHE GERAETE GMBHInventors: Claude Jolly, Anandhan Dhanasingh, Pavel Mistrik, Soeren Schilp, Roland Hessler, Kenneth Mugridge
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Patent number: 8529930Abstract: It is provided a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.Type: GrantFiled: September 11, 2009Date of Patent: September 10, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Patent number: 8529932Abstract: It is provided a method of treating a disorder, the method comprising implanting in a patient an implantable device including a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.Type: GrantFiled: September 11, 2009Date of Patent: September 10, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Patent number: 8529931Abstract: It is provided an implantable device including a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.Type: GrantFiled: September 11, 2009Date of Patent: September 10, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Patent number: 8524266Abstract: It is a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.Type: GrantFiled: September 11, 2009Date of Patent: September 3, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Patent number: 8512294Abstract: A medical device includes an antimicrobial layer. A method of depositing an antimicrobial agent on or in the body of a medical device includes inserting a high temperature resistant tube having multiple holes through its surface into a vascular access device and coating, or delivering an antimicrobial agent to, and interior surface of the device.Type: GrantFiled: July 26, 2007Date of Patent: August 20, 2013Assignee: Becton, Dickinson and CompanyInventors: David Ou-Yang, Wayne K. Rasmussen, Glade H. Howell, Lantao Guo
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Patent number: 8506538Abstract: A medical device for use in connection with a connector of an indwelling line for cleansing a surface of a septum of the connector is provided. The medical device includes a housing including a proximal portion defining a cavity containing a quantity of microbial reducing agent, a distal portion defining a cavity for selective coupling with the connector of the indwelling line, and a partition separating the proximal and distal cavities, wherein the proximal and distal cavities are in fluid communication with one another; and a deformable member overlying an end of the proximal portion for maintaining the microbial reducing agent within the proximal cavity thereof. The microbial reducing agent being dispensable into the distal cavity, at least when the medical device is connected to the connector of the indwelling line, to awash a surface of the connector of the indwelling line and reduce microbes present thereon.Type: GrantFiled: December 5, 2008Date of Patent: August 13, 2013Assignee: Covidien LPInventor: Todd M. Chelak
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Patent number: 8500939Abstract: Multi-lumen catheter devices having at least one split-tipped end are disclosed, together with methods of forming such split tip catheters. In one aspect of the invention, the manufacturing methods can include the steps of: providing a catheter body having at least a first and a second internal lumen extending longitudinally through the catheter body; removing a distal portion of the catheter body to form a first distal tip segment such that the first lumen extends longitudinally within this tip segment beyond the second lumen; and joining a second lumen tip segment to the catheter body in communication with the second lumen. The second tip segment can be joined to the catheter body such that it is at least partially separated from the first tip segment and, in some embodiments, preferably diverges at an angle relative to the first tip segment.Type: GrantFiled: October 2, 2008Date of Patent: August 6, 2013Assignee: Bard Access Systems, Inc.Inventors: Shekhar D. Nimkar, Christian Dufresne, Sr., Eric Tobin
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Publication number: 20130197455Abstract: The present disclosure relates to medical catheters, tubes, and other medical devices, systems, and methods. The catheter, tube, or other medical device is capable of releasing drugs for extended periods of time. Drugs can be loaded into the wall thereof with a loading solution. The drug in the wall of the device and in the loading solution can be in dynamic equilibrium, yielding stable and easy-to-manufacture products.Type: ApplicationFiled: March 30, 2011Publication date: August 1, 2013Applicant: SPARKMED RESEARCH, LLCInventor: Jie Zhang
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Publication number: 20130190701Abstract: A medical tube unclogging system includes a power supply, a reservoir of fluid, a tube for insertion into a lumen of a medical tube having a clog therein, a pump powered by the power supply and connected to the tube for generating a flow of fluid from the reservoir of fluid through the tube, a fitting through which the tube passes having a first opening coupled to the medical tube, a second opening for receiving the tube, and a third opening through which fluid pumped through the tube and into the medical tube, and fragments of the clog can be exhausted. The system may also include a sensor for monitoring a pressure of the fluid flowing through the tube and producing a signal indicative of the pressure, and a controller or processor for receiving the signal from the sensor and adjusting the pump.Type: ApplicationFiled: January 21, 2013Publication date: July 25, 2013Applicant: KIRN MEDICAL DESIGN LLCInventor: KIRN MEDICAL DESIGN LLC
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Publication number: 20130184659Abstract: A medical tube having improved lubricity is disclosed. The medical tube is produced by extruding a polymer material blended with a lubricity enhancing additive through a resilient die. The polymer material can be medical-grade high-density polyethylene, and the lubricity enhancing additive can be a silicone-based or alloy-based material. The medical tube can include one or more internal elongated protuberances so as to reduce the internal surface area of the medical tube available to generate friction on a guide wire inserted or withdrawn through the medical tube.Type: ApplicationFiled: December 20, 2012Publication date: July 18, 2013Applicant: CONTECH MEDICAL, INC.Inventor: Contech Medical, Inc.
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Patent number: 8486154Abstract: The device made in a resorbable material intended to be placed in urethra for Treatment of stricture has the shape of a tube (1), the wall of which has offices (2).Type: GrantFiled: November 6, 2006Date of Patent: July 16, 2013Assignee: Cerebel - Invest SAInventors: Raymond Andrieu, Philippe Le Goff, Milan Krajicek, Vaclav Vomacka
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Patent number: 8481138Abstract: Implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the implantable or insertable medical devices include at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.Type: GrantFiled: January 24, 2012Date of Patent: July 9, 2013Assignee: Boston Scientific Scimed, Inc.Inventors: Kathleen M Miller, Gregory T Sydney, Kurt Geitz, Peter L Dayton, Ronald A Sahatjian