Body Piercing Condit (e.g., Needle, Etc.) Patents (Class 604/272)
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Publication number: 20130158505Abstract: Disclosed are medical devices that incorporate siRNA. In addition to one or more siRNA constructs, devices include nanostructures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be incorporated on devices. The pattern including nanostructures may be formed on the surface of the microneedles.Type: ApplicationFiled: April 27, 2011Publication date: June 20, 2013Inventor: Russell Frederick Ross
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Publication number: 20130158483Abstract: A needle for the cannulation of a dialysis access graft that is less traumatic to the graft, and less likely to dislodge.Type: ApplicationFiled: February 28, 2012Publication date: June 20, 2013Inventor: Martin Senitko
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Patent number: 8465457Abstract: A hypodermic needle minimizing resistance to catheter advancement during vascular cannulation includes a needle shaft and a needle tip including an open needle bevel extending along middle and proximal portions of the open bevel until a distal end of the needle shaft, wherein a most distal portion of the open bevel is filled to prevent flashback. The hypodermic needle also includes a catheter overlying the needle shaft in the resting position.Type: GrantFiled: December 8, 2011Date of Patent: June 18, 2013Inventors: David G. Silverman, Sally A. Kniffin
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Publication number: 20130150789Abstract: Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body.Type: ApplicationFiled: February 11, 2013Publication date: June 13, 2013Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventor: BOSTON SCIENTIFIC SCIMED, INC.
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Patent number: 8460247Abstract: Catheter assemblies are generally discussed herein with particular discussions extended to catheter assemblies having a tip protector, a valve, a valve opener, and optionally a needle wiper. The valve opener is disposed inside a catheter hub and is configured to be pushed by an IV set luer connector to open a valve following successful catheterization to pass fluids or other solutions through the catheter. A tip protector is incorporated to block the needle tip and prevent the same from accidental needle stick. A wiper is optionally included to wipe blood deposits on the needle when the same is retracted from the catheter.Type: GrantFiled: February 28, 2012Date of Patent: June 11, 2013Assignee: B Braun Melsungen AGInventors: Kevin Woehr, Michael Zerbes
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Publication number: 20130144260Abstract: The present disclosure is directed to an injector device for delivering an ophthalmic solution to a cornea of an eye. The device may include a base configured to contact part of the eye, and a needle connected to the base, wherein needle may deliver the ophthalmic solution to the cornea.Type: ApplicationFiled: June 24, 2011Publication date: June 6, 2013Inventors: Bruce H. Dewoolfson, Donald Harris, Mike Luttrell, Gabriel Carpio
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Publication number: 20130144257Abstract: Disclosed are devices for delivering a rheumatoid arthritis drug across a dermal barrier. The devices include microneedles for penetrating the stratum corneum and also include structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The pattern of structures on the surface of the microneedles may include nano-sized structures.Type: ApplicationFiled: April 27, 2011Publication date: June 6, 2013Inventor: Russell Frederick Ross
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Publication number: 20130138080Abstract: A medical article is configured to provide access to a patient's vasculature. The medical article includes an elongated body and a pair of stabilizing wings that extend from the elongated body and are configured to stabilize the medical article on a patient. The stabilizing wings are configured to rotate together or independently about the longitudinal axis of the elongated body between at least a first configuration and a second configuration. The elongated body can include a one-way valve disposed therein. The medical article can also one or more adhesive layers configured to releasably attach at least a portion of the wings to a patient.Type: ApplicationFiled: March 2, 2011Publication date: May 30, 2013Applicant: VENETEC INTERNATIONAL, INC.Inventors: Rafael V. Andino, Christopher J. Brooks
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Publication number: 20130138053Abstract: Cannula and handle systems and cannulas having substantially continuous interior pathways or channels are provided. The interior pathway may extend from the inlet to the cannula to the outlet, such that tissue collected at the inlet is carried to the outlet without contacting other components. Moreover, the substantially continuous nature of the interior pathway, with an absence of drop-offs, blind pockets or other discontinuities, facilitates cleaning. In addition, inlet holes are sized to promote the transfer of tissue through the channel to the outlet, and to avoid damaging collected tissue. Holes included in the inlet can be oblong, and can be slanted with respect to a longitudinal axis of the cannula.Type: ApplicationFiled: November 14, 2012Publication date: May 30, 2013Inventor: Ronald D. Shippert
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Publication number: 20130116631Abstract: An adapter is placed between the needle and a conventional fluid store, or medical line. The end of the adapter that connects to the needle assembly is formed to have a configuration that is complementary to that of the hub of the needle assembly, so that the adapter and the needle hub may be readily mated to each other. The other end of the adapter is formed to have another configuration, for example a conventional luer, that is readily connectable to a conventional fluid store, such as a syringe that has a conventional luer. The adapter is formed by inter-fitting two elements to effect an integral locking mechanism to prevent the uncoupling of the fluid store and the adapter, once they are securely coupled.Type: ApplicationFiled: December 14, 2012Publication date: May 9, 2013Applicant: SMITHS MEDICAL ASD, INC.Inventors: Lynn A. Ziman, Steven Huu Nguyen
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Publication number: 20130116622Abstract: A medical device includes a catheter having an opening formed in a side portion of the catheter, an infusion tubing extending within the catheter along an axial direction of the catheter; an infusion needle disposed at a distal portion of the infusion tubing, a connecting part which bendably connects the infusion needle to the distal portion of the infusion tubing, and a bending unit by which the infusion needle located inside the catheter so as to face the opening is bent at the connecting part at essentially a right angle with respect to the distal portion of the infusion tubing.Type: ApplicationFiled: December 21, 2012Publication date: May 9, 2013Applicant: TERUMO KABUSHIKI KAISHAInventor: TERUMO KABUSHIKI KAISHA
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Publication number: 20130116523Abstract: The present invention relates to a method for fabricating a hollow microneedle having a variable appearance. The method makes it possible to vary the length of the microneedle, the outer and inner diameters of the upper and lower parts thereof, the aspect ratio, the sharpness, and the structural bending rate thereof, in accordance with the purposes of the same. Accordingly, the appearance of the hollow microneedles according to the present invention can be varied with flexibility according to various purposes, such as the transferring of medication and the taking of a blood sample, and to various factors, such as the target part for the medication transfer, the depth of the medication transfer, and the amount and viscosity of the medication. Thus, the microneedle can be used as a multi-purpose device for transferring medication.Type: ApplicationFiled: July 8, 2011Publication date: May 9, 2013Applicant: INCYTO CO., LTD.Inventors: Hyung II Jung, Kwang Lee, Sin Kil Cho, Young Dook Byeon
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Patent number: 8435261Abstract: Devices, methods and kits which, when installed or used, access, aspire, dilate, insufflate, drain or deliver fluid medicaments to, or place a patency device within a sinus area, such as a maxillary sinus or a maxillary sinus ostium. The device can include a hollow catheter and probe, and can be configured to permit gradual and incremental probe extension. The device can be constructed to enhance the precision and maneuverability within the nasal and sinus passageways, while also accommodating the natural anatomical geometry of a targeted paranasal treatment site. For example, the present treatment and placement device can accomplish access to the maxillary sinus ostium by utilizing an uncinate process to guide a probe tip into the ostium in a retrograde manner. The probe can be slidably, bi-directionally or co-axially positioned within the catheter. A distal portion of the probe can be biased away from a longitudinal axis of the catheter.Type: GrantFiled: July 15, 2010Date of Patent: May 7, 2013Assignee: Regents of the University of MinnesotaInventors: Benjamin Arcand, Joseph E. Hale, Nikhil Murdeshwar, Bryan Rolfes
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Patent number: 8425473Abstract: The invention provides surgical devices that provide access to the sub-retinal space using delicate traction to hold the sensory retina to create and maintain a patent sub-retinal space of sufficient size to introduce and perform treatments on the eye. Such treatments may include the introduction of illumination or imaging agents or tools, surgical tools, the infusion of pharmaceutical or biological agents, and the placement of grafts, transplants or implants and the closure of the site through the delivery of a sealant.Type: GrantFiled: January 23, 2009Date of Patent: April 23, 2013Assignee: iScience Interventional CorporationInventors: Friedrich Ho, Stanley R. Conston, Ronald K. Yamamoto
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Patent number: 8419708Abstract: It is intended to provide a transdermal drug administration apparatus having microneedles, which is capable of piercing the skin by a simple procedure in the transdermal administration of a biologically active substance (drug) and allows rapid absorption of the biologically active substance. The present apparatus comprises a microneedle device (50) comprising a microneedle substrate (53) having a plurality of microneedles (51) capable of piercing the skin, an absorbent (11) disposed thereon, the absorbent (11) comprising a material capable of absorbing a liquid, and a dissolving solution reservoir (18) disposed on the absorbent (11), the dissolving solution reservoir (18) containing a dissolving solution (16) for dissolving a drug and being capable of disrupting a diaphragm (20) provided the dissolving solution reservoir (18) and the absorbent (11) by pressing. A coating containing a dry drug is disposed on the microneedles (51) and/or the microneedle substrate (53).Type: GrantFiled: February 7, 2007Date of Patent: April 16, 2013Assignee: Hisamitsu Pharmaceuticals Co., Inc.Inventors: Seiji Tokumoto, Toshiyuki Matsudo, Tetsuji Kuwahara
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Patent number: 8419688Abstract: Catheter assemblies are generally discussed herein with particular discussions extended to catheter assemblies having a tip protector, a valve, a valve opener, and optionally a needle wiper. The valve opener is disposed inside a catheter hub and is configured to be pushed by an IV set luer connector to open a valve following successful catheterization to pass fluids or other solutions through the catheter. A tip protector is incorporated to block the needle tip and prevent the same from accidental needle stick. A wiper is optionally included to wipe blood deposits on the needle when the same is retracted from the catheter.Type: GrantFiled: April 27, 2010Date of Patent: April 16, 2013Assignee: B. Braun Melsungen AGInventors: Kevin Woehr, Michael Zerbes
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Patent number: 8414959Abstract: A method of coating a microneedle array by applying a coating fluid using a flexible film in a brush-like manner. A method of coating a microneedle array comprising: providing a microneedle array having a substrate and a plurality of microneedles; providing a flexible film; providing a coating solution comprising a carrier fluid and a coating material; applying the coating solution onto a first major surface of the flexible film; performing a transfer step of bringing the first major surface of the flexible film into contact with the microneedles and removing the flexible film from contact with the microneedles; and allowing the carrier fluid to evaporate.Type: GrantFiled: November 7, 2011Date of Patent: April 9, 2013Assignee: 3M Innovative Properties CompanyInventors: Choi Hye-Ok, Gordon P. Knutson, Moses M. David
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Patent number: 8414548Abstract: Microneedle arrays and drug delivery devices are provided for transdermally delivering a drug formulation to a patient. The microneedle array device includes a substantially planar substrate having an array of apertures; and a plurality of microneedles projecting at angle from the planar substrate, the microneedles having a base portion integrally connected to the substrate, a tip end portion distal to the base portion, and body portion therebetween, wherein each microneedle has at least one channel extending substantially from the base portion through at least a part of the body portion, the channel being open along at least part of the body portion and in fluid communication with at least one of the apertures in the substrate. In a preferred embodiment, each microneedle has a substantially rectangular cross-sectional shape and the channel is open to two opposing surfaces of the microneedle.Type: GrantFiled: January 27, 2010Date of Patent: April 9, 2013Inventor: Vadim V. Yuzhakov
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Publication number: 20130085472Abstract: The invention is directed to a nasal delivery device comprising one or more microneedles, and to methods of nasally administering a composition with a nasal delivery device comprising one or more microneedles. In certain embodiments, the nasal delivery device comprises a substrate for administration of a composition to the nasal and/or sinus mucosa, wherein the substrate is non-absorbent and comprises one or more microneedles. In some embodiments, the nasal delivery device comprises a reservoir comprising one or more therapeutic agents, wherein the reservoir is in fluid communication with one or more microneedles.Type: ApplicationFiled: March 9, 2011Publication date: April 4, 2013Applicant: Toxcure, LLCInventor: Christopher Shaari
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Patent number: 8402629Abstract: Provided is a method of manufacturing a hollow microneedle structure. The method includes coating a hollow core having a predetermined section and being long in a lengthwise direction with a coating solution, and solidifying the coating solution to form a coating layer, depositing a metal seed layer on the coating layer, plating the seed metal layer with a metal to form a plated layer, cutting the hollow core having the plated layer at an inclination angle with respect to the lengthwise direction for form a surface inclination, and removing the hollow core and the coating layer to form a hollow microneedle structure. Thus, the hollow microneedle structure can be manufactured to have such diameter, length, hardness, and inclination angle as to minimize pain. By use of the hollow core, the microneedle structure can have vertical microneedles with a uniform inner diameter.Type: GrantFiled: December 10, 2009Date of Patent: March 26, 2013Assignee: Electronics and Telecommunications Research InstituteInventors: Dae Sik Lee, Yong Sun Yoon, Moon Youn Jung, Seon Hee Park
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Patent number: 8403895Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: October 5, 2009Date of Patent: March 26, 2013Assignee: Spinal Restoration, Inc.Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
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Patent number: 8398596Abstract: A needle assembly comprises a metal needle (1) with a hub (13) and a marker in the form of a bubble-filled plastics rod (2) inserted within the needle. The rod (2) makes the assembly more visible under ultrasound observation when confirming correct placement of the needle (1) and is subsequently removed when correct placement has been confirmed.Type: GrantFiled: October 24, 2008Date of Patent: March 19, 2013Assignee: Smiths Group PLCInventor: Stephen James Field
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Patent number: 8398602Abstract: A carrying case (1) for a pharmaceutical injection device (21) administering a pharmaceutical to a living body includes a case unit (2, 20) and an electric charging device (3a). The case unit (2, 20) accommodates the pharmaceutical injection device (21). The electric charging device (3a) is mounted in the case unit (2, 20), includes an electric charging terminal (9) electrically connectable to the pharmaceutical injection device (21), and electrically charges the pharmaceutical injection device (21). The carrying case (1) can prevent troubles including such a situation that a user cannot charge the pharmaceutical injection device (21) while being out with the carrying case.Type: GrantFiled: October 2, 2009Date of Patent: March 19, 2013Assignee: Panasonic CorporationInventors: Toshiaki Ilo, Yukihiro Takabatake
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Publication number: 20130066200Abstract: A medical device for reducing the force necessary to penetrate living being tissue using a variety of reciprocating motion actuators, including piezoelectric, voice coil, solenoids, pneumatics or fluidics. The reciprocating actuator drives a penetrating member, such as a needle, through the tissue at a reduced force while the device detects the passage of the penetrating member through the tissue. Upon passage of the penetrating member through the tissue, electrical power to the reciprocating actuator is automatically terminated. One exemplary method for detecting this passage is via a fluid-containing syringe that is coupled to a channel within the penetrating member. Once the penetrating member tip has passed through the living tissue, the fluid within the syringe no longer experiences any pressure and a plunger within the syringe displaces indicating passage of the penetrating member tip.Type: ApplicationFiled: November 8, 2012Publication date: March 14, 2013Applicant: Actuated Medical, Inc.Inventors: Paul L. Frankhouser, Maureen L. Mulvihill, Brian M. Park
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Patent number: 8394064Abstract: The invention relates to a catheter introducer comprising: a tube-like introducer sheath; an introducer hub having a distal section and a proximal section, wherein the distal section is joined to the proximal end of the introducer sheath and the proximal section defines a chamber; a needle extending through the introducer hub and the introducer sheath and having opposite proximal and distal ends, the distal end forming a needle tip; a needle hub attached to the proximal end of the needle; a needle safety device slidably arranged on the needle, wherein the needle safety device is retained in the chamber of the introducer hub when the needle extends through the introducer hub and the introducer sheath, and removable from the introducer hub once the needle tip is received in the needle safety device upon withdrawal of the needle from the introducer sheath.Type: GrantFiled: February 3, 2011Date of Patent: March 12, 2013Assignee: Poly Medicure Ltd.Inventor: Rishi Baid
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Patent number: 8394050Abstract: A straight cutting tip for a straight bore subcutaneous implantation instrument is provided. An incising shaft body defines an axial bore extending continuously throughout the incising shaft body's length. The axial bore is open on both distal and proximal ends of the incising shaft body and has a non-circular cross section of at least five millimeters. A beveled surface is transversely formed beginning on a top surface and ending on a bottom surface of the distal end of the incising shaft body. A straight and sharpened cutting edge with rounded ends on each side curves inwardly towards the proximal end of the incising shaft body. The cutting edge is defined only along a bottom distal edge of the beveled surface. An attachment point is formed on the proximal end of the incising shaft body.Type: GrantFiled: August 23, 2010Date of Patent: March 12, 2013Assignee: Cardiac Science CorporationInventor: Gust H. Bardy
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Patent number: 8394072Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: October 5, 2009Date of Patent: March 12, 2013Assignee: Spinal Restoration, Inc.Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
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Patent number: 8389023Abstract: Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.Type: GrantFiled: September 23, 2011Date of Patent: March 5, 2013Assignee: Boston Scientific Scimed, Inc.Inventor: Joseph V. DiTrolio
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Publication number: 20130053791Abstract: A needle assembly has a needle hub that has a body to which are formed two plates at opposite sides thereof in a parallel relationship. The plates have respective upper edges and lower edges that lie substantially along respective planes, so that the needle hub may be stably placed onto a surface by means of the respective edges. The plates also prevent the rolling of the needle between the fingers of the clinician when the clinician holds the needle assembly by means of the plates. A partition is formed orthogonally proximate to the front ends of the parallel plates. The connector at the proximal portion of the needle hub is configured to have a non-conventional configuration that allows it to mate only with a counterpart connector that has a complementary non-conventional configuration.Type: ApplicationFiled: August 6, 2012Publication date: February 28, 2013Applicant: Smiths Medical ASD, Inc.Inventor: Geoff Clark
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Patent number: 8382722Abstract: A method of manufacturing a metal cannula is disclosed. The method includes the step of providing a metal cannula having a longitudinal axis and defining a fluid channel. Next, the metal cannula is pressed to substantially close the fluid channel and define a first segment and a second segment. In a next step, the metal cannula is cut to separate the first segment from the second segment of the metal cannula. Each of the first and second segments have a pressed edge. The pressed edge substantially seals the fluid channel and has two pressed corners. Afterwards, each of the pressed corners are cut from the pressed edge of the first segment to define a pair of side openings and a distal blunt edge on the first segment. The side openings are in fluid communication with the fluid channel.Type: GrantFiled: June 30, 2008Date of Patent: February 26, 2013Assignee: Covidien LPInventors: James L. Carlyon, Gregory Steube
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Patent number: 8382714Abstract: A rail-guided epidural-spinal needle, which includes an epidural needle including a base and a needle shaft connected to the base, the needle shaft having a groove that is formed on an outer surface of the needle shaft and extends along an axis of the needle shaft, the base having an elevated spinal needle inlet disposed thereon, the spinal needle inlet having a conduit formed therein, the conduit being of an acute angle with the groove in a side view of the epidural needle, and being in alignment with the groove in a top view of the epidural needle. The rail-guided epidural-spinal needle also includes a spinal needle having a tip with a unilaterally curved conformation down one side, such that, when the spinal needle is inserted into the conduit of the spinal needle inlet, and pushed forward, the tip thereof reaches the groove and slides along the groove.Type: GrantFiled: May 20, 2011Date of Patent: February 26, 2013Inventor: Yihui Wen
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Publication number: 20130046255Abstract: An adapter is placed between the needle and a conventional fluid store, or medical line. The end of the adapter that connects to the needle assembly is formed to have a configuration that is complementary to that of the hub of the needle assembly, so that the adapter and the needle hub may be readily mated to each other. The other end of the adapter is formed to have another configuration, for example a conventional luer, that is readily connectable to a conventional fluid store, such as a syringe that has a conventional luer. The adapter is formed by inter-fitting two elements to effect an integral locking mechanism to prevent the uncoupling of the fluid store and the adapter, once they are securely coupled.Type: ApplicationFiled: September 12, 2012Publication date: February 21, 2013Applicant: SMITHS MEDICAL ASD, INC.Inventors: Lynn A. ZIMAN, Steven Huu Nguyen
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Patent number: 8377364Abstract: The invention discloses a method of manufacturing a microneedle including the steps of forming an island etching mask having thickness distribution on a substrate, and processing the substrate into a needle by taking advantage of a difference in etching rates between the etching mask and the substrate. The invention enables to readily control a point angle and height of the manufactured needle.Type: GrantFiled: March 29, 2010Date of Patent: February 19, 2013Assignee: Toppan Printing Co., Ltd.Inventors: Kazuhiko Shiomitsu, Hiroshi Sugimura, Toshiaki Kurosu, Gaku Suzuki, Takao Tomono
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Needle for directional control of the injection of bone cement into a vertebral compression fracture
Patent number: 8377013Abstract: A needle for use in a surgical procedure includes an outer cannula including a shaft portion having a side wall and an end wall. A first aperture extends through the side wall of the outer cannula, and a second aperture extending through the end of the outer cannula. The needle also includes an inner cannula that is disposed within the outer cannula and includes a shaft portion having a bore extending therethrough. The inner cannula is selectively movable relative to the outer cannula between a first orientation and a second orientation. In the first orientation, communication is provided between the bore of the inner cannula and a first external region that is located adjacent to the second end of the outer cannula. In the second orientation, communication is provided between the bore of the inner cannula and a second external region that is located adjacent to the second end of the outer cannula.Type: GrantFiled: July 12, 2010Date of Patent: February 19, 2013Assignee: The University of ToledoInventor: Ashok Biyani -
Publication number: 20130041330Abstract: The present invention provides a micro-needle device that includes a substrate, a micro-needle provided on the substrate, and a physiologically active composition deposited on the micro-needle and/or the substrate. In the micro-needle device, the physiologically active composition contains: at least one polyhydric alcohol selected from glycerin, ethylene glycol, propylene glycol and 1,3-butylene glycol; and a physiologically active substance, and contains substantially no water.Type: ApplicationFiled: February 24, 2011Publication date: February 14, 2013Applicant: HISAMITSU PHARMACEUTICAL CO., INC.Inventors: Toshiyuki Matsudo, Shinpei Nishimura, Seiji Tokumoto, Kumi Morimoto
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Patent number: 8372032Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.Type: GrantFiled: August 9, 2007Date of Patent: February 12, 2013Assignee: The Invention Science Fund I, LLCInventor: Lowell L. Wood, Jr.
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Publication number: 20130035632Abstract: The invention provides decomposing apparatus which comprises a first sub-component and a first micro device comprising a decomposable material, wherein the sub-component comprises a drug, a medical kit, a micro-disease detection system, or an auto-navigation system. Also within the invention are methods for fabricating such apparatus.Type: ApplicationFiled: August 2, 2011Publication date: February 7, 2013Inventors: Chris C. Yu, Xuedong Du
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Patent number: 8366677Abstract: The present invention provides for transdermal delivery devices having microneedle arrays, as well as methods for their manufacture and use. In one embodiment, a transdermal delivery device is provided. The transdermal delivery device includes a polymer layer which has microneedles projecting from one of its surfaces. The microneedles are compositionally homogenous with the polymer base layer.Type: GrantFiled: August 6, 2008Date of Patent: February 5, 2013Assignee: Transderm, Inc.Inventors: Roger L. Kaspar, Tycho Speaker
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Publication number: 20130030390Abstract: Needle comprising a polyarylene material comprising a polyarylene. The needle can meet all the advantages of metal, while avoiding its drawbacks. It has a high rigidity and ductility, and is excellent in penetrability and ability to hold a sharp edge. It is easily disposable and recyclable. It is non toxic and non irritant.Type: ApplicationFiled: March 16, 2011Publication date: January 31, 2013Applicant: SOLVAY SPECIALTY POLYMERS USA, LLCInventors: Jean-Baptiste Bonnadier, Daniel J. Ireland, Henri Massillon
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Publication number: 20130030391Abstract: The invention relates to a catheter apparatus comprising: a catheter; a catheter hub having a distal section and a proximal section, wherein the distal section is joined to the catheter and the proximal section defines a chamber; a needle extending through the catheter hub and the catheter and defining an axial direction, wherein the needle has opposite proximal and distal ends, the distal end forming a needle tip; a needle hub attached to the proximal end of the needle; and a needle guard slidably arranged on the needle, wherein the needle guard is retained in the chamber of the catheter hub when the needle extends through the catheter hub and the catheter, and wherein the needle guard is removable from the catheter hub once the needle tip is received in the needle guard upon withdrawal of the needle from the catheter.Type: ApplicationFiled: May 20, 2010Publication date: January 31, 2013Applicant: POLY MEDICURE LIMITEDInventor: Rishi Baid
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Patent number: 8361037Abstract: The microneedle devices disclosed herein in some embodiments include a substrate; one or more microneedles; and, optionally, a reservoir for delivery of drugs or collection of analyte, as well as pump(s), sensor(s), and/or microprocessor(s) to control the interaction of the foregoing.Type: GrantFiled: September 19, 2002Date of Patent: January 29, 2013Assignee: Valeritas, Inc.Inventor: Robert R. Gonnelli
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Patent number: 8361013Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.Type: GrantFiled: April 19, 2004Date of Patent: January 29, 2013Assignee: The Invention Science Fund I, LLCInventor: Lowell L. Wood, Jr.
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Patent number: 8361014Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.Type: GrantFiled: August 9, 2007Date of Patent: January 29, 2013Assignee: The Invention Science Fund I, LLCInventor: Lowell L. Wood, Jr.
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Patent number: 8353881Abstract: Devices and methods for delivering a therapeutic substance to a patient are provided. Embodiments include infusion sets that include an active agent. Also provided are systems and kits.Type: GrantFiled: December 28, 2005Date of Patent: January 15, 2013Assignee: Abbott Diabetes Care Inc.Inventor: R. Curtis Jennewine
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Patent number: 8348908Abstract: A regional anesthesia catheter used with a guide such as for example a needle cannula has a distal portion integrally connected to a main portion of the catheter by a junction portion that has a cross-sectional profile different from the distal and main portions, so as to predispose the distal portion of the catheter to move in a given direction when the distal portion is not guided by or constrained by the needle cannula. The cross-sectional profile of the junction portion may be configured in a particular shape, or be constructed to have a flexibility that predisposes the distal portion to bend, curve or move toward a given direction.Type: GrantFiled: December 16, 2004Date of Patent: January 8, 2013Assignee: Smiths Medical ASD, Inc.Inventor: David Jason Tucker
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Publication number: 20130006147Abstract: Provided are a medical needle and a puncturing instrument which make it possible to administer a predetermined amount of a substance to be administered into a living body and/or collect a predetermined amount of an object to be collected from within the living body with ease and accuracy. A medical needle (1) is provided with a puncturing part (10) which can penetrate into the living body. The puncturing part (10) has a pair of planar portions (12, 12) which are parallel to each other in an outer surface and a retaining chamber (18) defined within the puncturing part (10), the retaining chamber (18) passing through the puncturing part (10) and opening to the pair of planar portions (12) on each side. A puncturing instrument can be structured by accommodating the medical needle (1) in a casing in such a way that the medical needle (1) can project therefrom.Type: ApplicationFiled: March 2, 2011Publication date: January 3, 2013Applicant: LIGHTNIX, INC.Inventor: Mitsuo Fukuda
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Publication number: 20130006219Abstract: An applicator used to apply microneedle arrays to a mammal In particular, an application device for applying a microneedle device to a skin surface comprising a flexible sheet having a raised central area attached to the microneedle device and a supporting member at or near the periphery of the flexible sheet, wherein the flexible sheet is configured such that it will undergo a stepwise motion in the direction orthogonal to the major plane of the sheet.Type: ApplicationFiled: September 12, 2012Publication date: January 3, 2013Inventors: Adam S. Cantor, Franklyn L. Frederickson, Peter R. Johnson, Ted K. Ringsred
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Publication number: 20130006201Abstract: Embodiments are directed to eluting coils having a relaxed coiled state and a straightened state that may be deployed at a fixed location within a patient's body and may accurately dispense and distribute fluids and or dissolvable substances at site specific locations of the body. Some embodiments of eluting elements are configured to be subsequently retrieved from a delivery site.Type: ApplicationFiled: September 11, 2012Publication date: January 3, 2013Inventor: John L. Wardle
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Publication number: 20120330250Abstract: An object of the present invention is to efficiently inject a drug (physiologically active substance). Therefore, a micro-needle device 1 comprises a base plate 2 and a micro-needle 3 installed on the base plate 2. A coating agent containing the physiologically active substance is coated at least at a part of the micro-needle 3, and a coating range thereof is 100 to 230 ?m including the top of the micro-needle 3. A load due to the energy of 0.2 to 0.7 J/cm2 is applied to the micro-needle device 1 which is in contact with the skin.Type: ApplicationFiled: February 24, 2011Publication date: December 27, 2012Applicant: HISAMITSU PHARMACEUTICAL CO., INC.Inventors: Tetsuji Kuwahara, Seiji Tokumoto, Kazuya Machida
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Publication number: 20120328600Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: ApplicationFiled: June 26, 2012Publication date: December 27, 2012Inventors: Brian D. Burkinshaw, Steven I. Whitlock, Kevin Pauza, Mark I. Richards, James B. Rogan