Abstract: Methods and devices for handling a fluid and delivering the fluid to the eye. The device has a vibrating element with a plurality of openings through which a fluid is ejected when the vibrated. An enclosure defines a chamber which holds a single application of the fluid. The enclosure may be biased against the vibrating element with a spring load developed in whole or part by the resilient structure of the enclosure. The chamber may be substantially empty after the single application.

Abstract: The disclosure relates to an audible indicator for use with a drug delivery device comprising a bistable resilient force member capable of residing in two states. In a biased state, the resilient force member is biased and stores energy In a relaxed state, the resilient force member is relaxed. The resilient force member releases the stored energy when transitioning from the biased state into the relaxed state, thereby generating an audible signal.

Abstract: Devices, systems, compositions and methods for long term or prolonged transdermal administration of an active agent are provided.

Abstract: A medical agent delivery device may comprise a collapsible reservoir and a base portion including at least one microneedle on a first face and on an opposing second face. Each microneedle on the first face may fluidically communicate with a microneedle on the second face. The device may further comprise an elastomeric housing attached to the first face. The reservoir and the at least one microneedle on the first face of the base portion may be within the elastomeric housing. The device may further comprise a displaceable spacer having a first position in which the spacer supports the reservoir in spaced relation to the at least one microneedle on the first side of the base portion. When the spacer is in a second position, the elastomeric housing may be configured to press the reservoir into the at least one microneedle on the first side of the base portion.

Abstract: Devices, systems, compositions and methods for long term or prolonged transdermal administration of an active agent are provided.

Abstract: A wound packing material is provided, suitable for use in negative pressure wound therapy, including a body of a porous material, the body including frangible regions defining a plurality of portions, the frangible regions allowing the portions to be selectively removed from the body. Methods of manufacturing the wound packing material, and methods of its use are also provided.

Abstract: A condom comprises, on one or more surfaces thereof, a self-lubricating coating comprising a dry powder having a particle size of 300 microns or less. The self-lubricating coating becomes lubricious when the coating comes into contact with a liquid environment. A method of making a self-lubricating condom comprises providing a dry condom and coating said condom, on one or more surfaces thereof, with a self-lubricating coating comprising a dry powder. The invention also provides the use of a dry powder such as xanthan gum to provide a self-lubricating coating for a condom.

Abstract: Systems and methods enable video on demand playback startup times to be reduced. A redirect database is populated with redirect locators. A request from a device for an item of primary video content is received. A static manifest file is generated including locators corresponding to the requested item of primary video content and redirect database entries storing redirect locators to default interstitial media. The static manifest file is transmitted to the device. Potential items of interstitial media are identified by sources of interstitial media, and a first item of interstitial media is selected. A redirect locator in the redirect database is replaced with a redirect locator corresponding to the selected interstitial media. A request is received from the device directed to the redirect database location storing the redirect locator corresponding to the selected interstitial media. The selected interstitial media is streamed to the device.

Abstract: Medaide is the only product of its kind that provides a band-aid strategically developed with a medicine carrier reservoir that can be easily puncture to release medication onto an affected skin site. This unprecedented product is uniquely designed with a durable adhesive skin color semi-transparent band-aid to complement diverse users and comes individually packed for easy transport and to preserve the sanitization of each covering.

Abstract: Aspects of the subject disclosure may include, for example, transmitting a first request that includes a key, wherein the key identifies: a processing system that is a targeted recipient of an advertisement, a stream in which a primary content item is being provisioned to the processing system, and a service provider, based at least in part on the transmitting of the first request, obtaining information pertaining to an advertisement from a device of the service provider, and inserting the information within a portion of the stream corresponding to a break in the primary content item. Other embodiments are disclosed.

Abstract: Provided herein is a system and method for mitigating premature light deactivation of light deactivated adhesive drapes. One aspect provides a system comprising a drape, a photosensitive adhesive layer, a release agent, and an optical fiber mesh layer configured as a light pipe, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimulus such as certain wavelengths of light. Another aspect includes a pipe light pipe, as an alternative to the optical fiber mesh layer. The systems may have a removable blocking layer to prevent the photosensitive adhesive from being exposed to deactivation wavelengths prematurely. Another aspect provides a method for application and removal of a drape using the light pipe to transport or route light to the drape to deactivate the photosensitive adhesive layer and promote easy, clean, and less painful removal of the drape.

Abstract: Provided herein is a system and method for mitigating premature light deactivation of light deactivated adhesive drapes. One aspect provides a system comprising a drape, an adhesive layer, and a release agent, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimulus such as certain wavelengths of light. The system may have a photochromic layer that may transition between a blocking transmittance state and a non-blocking transmittance state to block or allow certain wavelengths of light to pass through. Some systems may use a combination of a photochromic layer and a filter layer to prevent the adhesive from being exposed to deactivation wavelengths prematurely. Another aspect provides a method for application and removal of a drape using by removing one or more of a photochromic layer and a filter layer and applying light to the drape to deactivate the adhesive layer and promote easy, clean, and less painful removal of the drape.

Abstract: According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

Abstract: Various embodiments of the present invention relate to a device and a method for detecting a black bar in video content in an electronic device. An electronic device comprises a display device, a processor, and a memory automatically connected with the processor, wherein the memory, when executed, can store instructions for allowing the processor to: play video content on the basis of a request relating to the playing of the video content; acquire, on the basis of the request relating to the playing of the video content, time information relating to the detection period of a black bar included in the video content; detect, on the basis of the time information, the black bar by using at least one image frame of the video content included in the detection period, when the detection period arrives while the video content is played; and adjust, on the basis of the black bar included in the video content and the resolution of the display device, the size of an image area of the video content being played.

Abstract: The present disclosure provides a biological fluid collection device, such as a blood collection device, that is adapted to receive a multi-component blood sample having a cellular portion and a plasma portion and quickly, efficiently and cost-effectively separate the plasma portion from the sample. A pressure gradient can be applied across a separation member to facilitate movement of the plasma portion ahead of the cellular portion. The present disclosure allows for both passive and active plasma separation and dispensing.

Abstract: Applicator (3) for cold treatment, comprising an applicator housing (5) with an inlet opening (18) and a leak tight tip (23). The applicator housing (5) encloses a channel body (20) extending between the inlet opening (18) and the leak tight tip (23). The applicator (3) is mounted or mountable in a releasable manner onto a pressurized dispenser (2) comprising a nozzle (7), such that the inlet opening (18) is in fluid communication with the nozzle (7). The applicator housing (5) is moveable between a rest position and a pressed position to activate the nozzle (7). The applicator housing (5) has release openings (26) which are closed in the pressed position.

Abstract: A content server may receive from a user device a request for a content asset and may send to the playback device a permit for accessing the content asset. The permit may be used by the content server in order to enforce a concurrency restriction, or a number of concurrent playbacks of one or more content assets desired or permitted by the playback device. In response to receiving a request for a content asset segment associated with a content asset, the content server may determine whether the number of permits currently granted to the playback device exceeds the number of desired or permitted accesses by the playback device, or a group of playback devices, to the content asset or one or more content assets. If so, then the content server may discontinue sending to the playback device any further content asset segments associated with that content asset.

Abstract: A dispensing apparatus (1) for delivering droplets of fluids such as liquids having a low viscosity or being soft gels onto poultry hatchlings that are present in movably mounted hatchling trays (19) comprising at least one reservoir (18), at least one pumping unit (9), connected to at least one reservoir (18), with at least one manifold (8) connected to at least one pumping unit (9), as well as a control unit. The apparatus comprises a plurality of optionally adjustable fluid atomizers (6) being connected by flexible connecting means (7) to at least one manifold (8), whereby the fluid atomizers (6) are detachably and/or slidably connected on at least one mounting rail (5), and that optionally different types of fluid atomizers (6) are distributed onto the mounting rail (5). Additionally, a method for delivering fluid droplets onto poultry hatchlings present in moving hatchling trays (19) is described.

Abstract: The invention relates to systems formed from closed liquid-tight packaging and a preferably dimensionally stable aqueous composition which is sealed therein and which, upon activation, releases a liquid phase essentially composed of water in a time-delayed manner. The invention further relates to methods for manufacturing such systems and the use thereof during the production of self-decomposing transdermal therapeutic systems (TTS).

Abstract: A surgical evacuation apparatus and method for evacuating a biological material from a body cavity. The surgical evacuation apparatus has a shaft and a scoop extending from a distal end of the shaft. The shaft has a supply inlet for connecting to a pressurized fluid source and an outlet for connecting to a vacuum source. An evacuation channel extends from the scoop to the outlet. A fluid supply channel extends in the shaft from the supply inlet towards the distal end and intersects the evacuation channel proximate the scoop. Material desired to be removed from the body cavity is collected in the scoop by a user. The biological material collected in the scoop is broken up by a fluid stream from the supply channel and is drawn into the evacuation channel by a vacuum applied by the vacuum source and is removed from the body cavity.

Abstract: Systems and methods enable video on demand playback startup times to be reduced. A redirect database is populated with redirect locators. A request from a device for an item of primary video content is received. A static manifest file is generated including locators corresponding to the requested item of primary video content and redirect database entries storing redirect locators to default interstitial media. The static manifest file is transmitted to the device. Potential items of interstitial media are identified by sources of interstitial media, and a first item of interstitial media is selected. A redirect locator in the redirect database is replaced with a redirect locator corresponding to the selected interstitial media. A request is received from the device directed to the redirect database location storing the redirect locator corresponding to the selected interstitial media. The selected interstitial media is streamed to the device.

Abstract: In some illustrative examples, a bridge suitable for treating a tissue site may include a bridge sealing member and one or more bridge wicking layers. The bridge sealing member may extend along a length of the bridge, and may define an internal passageway in fluid communication between a receiving end of the bridge and a transmitting end of the bridge. The one or more bridge wicking layers may be disposed within the internal passageway of the bridge sealing member. Other apparatus, systems, and methods are disclosed.

Abstract: The present invention relates to a composition for hemostasis which contains collagen, stabilizer, and thrombin, and a container including the same. The present invention is applicable to a bleeding patient requiring emergency treatment with a simple method of use. There is no toxicity and no problem of blood infection. A biodegradation rate is fast. In this regard, the present invention achieves an excellent hemostatic effect. Therefore, the composition for hemostasis is useful as a hemostat.

Abstract: Methods of fabricating three-dimensional objects featuring properties of a soft bodily tissue and three-dimensional objects featuring properties of a soft bodily tissue or of an organ comprising same are provided.

Abstract: The present invention relates to compositions comprising a colloidal dispersion and an Agent of Interest (“AOI”), wherein the colloidal dispersion comprises deformable colloidal particles and wherein the AOI is not associated with the deformable colloidal particles. The present invention also provides kits and transdermal drug release devices comprising the compositions of the present invention, and the use of these compositions in medicine, skin care and cosmetics.

Abstract: According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

Abstract: A wound care device for delivering topical oxygen therapy, negative pressure wound therapy, and a low intensity vacuum therapy for treatment of a wound. The wound care device may include an oxygen supply MEA, an oxygen consuming MEA, a vacuum pump and motor, a pressure sensor, and a power supply and electronic controls. A dressing may be connected to the wound care device for administering topical continuous oxygen therapy and simultaneous negative pressure wound therapy to a wound. A canister or exudate trap may be positioned between the dressing and the vacuum supply port of the vacuum pump to collect and store exudates from the wound. The canister may be combined with the dressing.

Abstract: A depth detection apparatus, in particular in intracorneal dissection, provides a perforating tubular element suitable for being inserted into the cornea, a reciprocally moving air volume generator (14) connected to the perforating tubular element, a pressure sensor for detecting the pressure along the connection between the volumetric generator and the perforating element in the reciprocal movement of the volumetric generator, a microcontroller connected to the pressure sensor to detect pressure variations with the depth advancement into the cornea of the perforating element, a signaller connected to the microcontroller to signal that a preset pressure variation has been reached. The apparatus enables a correct position to be determined for performing intracorneal dissection.

Abstract: Aspects of the subject disclosure may include, for example, transmitting a first request that includes a key, wherein the key identifies: a processing system that is a targeted recipient of an advertisement, a stream in which a primary content item is being provisioned to the processing system, and a service provider, based at least in part on the transmitting of the first request, obtaining information pertaining to an advertisement from a device of the service provider, and inserting the information within a portion of the stream corresponding to a break in the primary content item. Other embodiments are disclosed.

Abstract: A system comprising a preservative-removing polymeric matrix comprising an active matrix component and an inactive matrix component. A method for administering an ophthalmic agent comprises providing a solution, emulsion, or suspension comprising an ophthalmic agent, and a preservative; and providing a preservative-removing polymeric matrix comprising an active matrix component and an inactive matrix component, and wherein the polymeric matrix is configured to selectively absorb the preservative when the solution, emulsion, or suspension is passed therethrough.

Abstract: Systems and methods enable video on demand playback startup times to be reduced. A redirect database is populated with redirect locators. A request from a device for an item of primary video content is received. A static manifest file is generated including locators corresponding to the requested item of primary video content and redirect database entries storing redirect locators to default interstitial media. The static manifest file is transmitted to the device. Potential items of interstitial media are identified by sources of interstitial media, and a first item of interstitial media is selected. A redirect locator in the redirect database is replaced with a redirect locator corresponding to the selected interstitial media. A request is received from the device directed to the redirect database location storing the redirect locator corresponding to the selected interstitial media. The selected interstitial media is streamed to the device.

Abstract: A negative pressure wound therapy system includes at least one sensor coupled to a wound dressing for a wound of a patient, and a processing circuit. The at least one sensor is configured to output a measurement of the pressure in the wound dressing. The processing circuit is configured to open a sealable aperture, receive the pressure measurements in the wound dressing, calculate a rate of pressure decay, correlate the rate of pressure decay in the wound dressing to a wound dressing fluid absorbent capacity and other therapy parameters, and output the wound dressing fluid absorbent capacity and other therapy parameters to a remote electronic device.

Abstract: The subject invention is a standardized system that provides for the methodical performance of a variety of procedures, which is designed to be configured as a variety of single-use devices, each in the form of a procedure kit which corresponds to a particular type of procedure, organized with all the exact components necessary to perform such particular type of procedure, in accordance with the included step-by-step instructions of a proprietary protocol with which such components correlate. This standardized system for performing a variety of procedures, and the methodical approach for performing each corresponding proprietary protocol, can improve the precision and efficiency of each procedure and, thereby reduce the chance of errors, minimize waste, increase productivity and provide for consistent outcomes.

Abstract: A pump generates a vacuum at a wound site via first tubing. A negative pressure circuit is defined by a canister, the first tubing and the wound site. A controller of a therapy device operates the pump to apply a first negative pressure to the entirety of the negative pressure circuit, following which ambient air is allowed to flow into the negative pressure circuit. The controller also operates the pump to apply a second negative pressure to a selected portion of the negative pressure circuit exclusive of the wound site, following which ambient air is allowed to flow into the selected portion. A quantity of fluid to be delivered to the wound site via a second tubing is determined by comparing measured parameters related to the flow of air into the negative pressure circuit to parameters measured with respect to the flow of air into the selected portion.

Abstract: Peroxyformic acid compositions for removal of biofilm growth and other contaminants and impurities from industrial processing hard surfaces are disclosed. In particular, peroxyformic acid compositions may be dosed on site and/or generated in situ for the reduction and prevention of biofilms on the hard surfaces. Methods of employing the peroxyformic acid compositions for removal of biofilm growth and other impurities such as aldehydes and alcohols from industrial CO2 effluent are also disclosed which beneficially provide ambient biofilm control and break down more rapidly than other peracids, allowing for extended runs between CIP cleaning, including a reduction and/or elimination of cleaning of the scrubbers and other industrial surfaces.

Abstract: A liquid indicating article is disclosed. It can have a single layer, but generally will have at least two layers bonded together, wherein a visible layer masks a second colored layer and the visible layer becomes at least semitransparent when wet.

Abstract: In some illustrative embodiments, a system suitable for treating a tissue site may include a dressing, a low-profile conduit, a conduit interface, and a reduced-pressure source. The dressing may be adapted for positioning at the tissue site. The low-profile conduit may be adapted for fluidly coupling to the dressing. The low-profile conduit may include a manifold and a sealing member encapsulating the manifold. The conduit interface may be adapted for fluidly coupling to the low-profile conduit. The conduit interface may be in fluid communication with the dressing through the low-profile conduit. The reduced-pressure source may be adapted for fluid communication with the conduit interface. Other systems, devices, and methods are disclosed.

Abstract: A system and a method for measuring ultraviolet ray protection of a cosmetic material. In an embodiment, the system for measuring the ultraviolet ray protection of a cosmetic material includes: a light source for emitting light including ultraviolet bands; a transparent plate through which the lights emitted from the light source pass, and having one surface to which a cosmetic material to be tested is applied; a wavelength conversion film, which changes, to a predetermined size, the light, of an ultraviolet band, of the light having passed through the transparent plate and makes the same pass therethrough; and a photosensitive sheet, which accommodates the light having passed through the wavelength conversion film and has a photosensitive property for light of UVA and UVB bands among the ultraviolet bands.

Abstract: A device for deposition of particles on a target from a transparent slide having a film formed by a fluid containing suspended particles, by locally exciting the film using a laser, includes means for observing the local excitation region. The observation means comprise a sensor and a light source, the optical axes of which are substantially shared in a space between an optical splitter and the film. The optical beam of the imaging system and the optical beam of the laser are coaxially arranged in the space between the controlled optical deflection means and the film. The device comprises a first focusing optical unit arranged between the controlled optical deflection means and the film. The device comprises a second image-combining optical unit positioned between the sensor and the splitter, the sensor being positioned in the focal plane of the second optical unit.

Abstract: The present disclosure is directed to random, acrylic co-polymers that are useful in transdermal applications. Methods of making and using the described co-polymers are also described.

Abstract: An applicator for dispensing a solution having two or more components includes a hollow body having a head provided at one end of the hollow body for dispersion of the solution and a breaking mechanism attached to the hollow body. The breaking mechanism includes at least one projection extendable into an interior of the hollow body. The applicator further includes a plurality of ampoules placed in the interior of the hollow body. The plurality of ampoules contains the two or more components. Upon activation of the breaking mechanism, the at least one projection applies a force to the plurality of ampoules such that the plurality of ampoules break and release the two or more components to form the solution.

Abstract: The present invention relates to sanitary protection article that is structured and arranged to maintain menstrual fluid within the vagina and thereby prevent the menstrual fluid from escaping the body. The present invention also relates to a method of selectively maintaining menstrual fluid within the vagina by means of using such article.

Abstract: Apparatus and methods for additive manufacturing with variable extruder profiles are described herein. An extruder print head with multiple nozzles placed at different angles allows for additional degrees of freedom to additively manufacture parts with complex shapes. In addition with the use of shape memory alloy materials, the diameter of one or more nozzles can be adjusted during the additive manufacturing process. This allows for independent control of the build resolution and of the build rate.

Abstract: An article of manufacture has an external surface at least partly defined by a material compositionally comprising a polymeric hydrogel that takes up water when wetted. The hydrogel-containing material is effective in reducing soil accumulation on, and/or for reducing soil adhesion to, an article designed for a variety of uses, such as transportation, vehicle safety, storage, recreation, leisure, waste disposal, construction, gardening, or traffic control.

Abstract: Apple cider vinegar, may be applied in different ways to the skin, the preferred way of application is a cream or a lotion which can be left on the skin for 10-15 minutes or preferably overnight. The objectionable odor of vinegar is masked or eliminated by the inclusion of certain natural essential oils such as lavender oil, rose oil, rosewood oil, geranium oil, tea tree oil, rosemary oil, sandalwood oil, lemongrass oil, violet oil and ginger oil. These natural essential oils also practically eliminate any potential skin irritation that may result from high concentrations of the vinegar.

Abstract: A wound care device for delivering topical oxygen therapy and negative pressure wound therapy for treatment of a wound. The wound care device may include an oxygen supply membrane electrode device (MEA), a vacuum pump and motor, a pressure sensor, and a power supply and electronic controls. A dressing may be connected to the wound care device for administering topical continuous oxygen therapy and negative pressure wound therapy to a wound. The wound care device may be operated to provide simultaneous topical oxygen therapy and negative pressure wound therapy, continuous oxygen therapy with intermittent negative pressure wound therapy, and alternating oxygen therapy and negative pressure wound therapy.

Abstract: A wound care device for delivering topical oxygen therapy, negative pressure wound therapy, and a low intensity vacuum therapy for treatment of a wound. The wound care device may include an oxygen supply mea, an oxygen consuming mea, a vacuum pump and motor, a pressure sensor, and a power supply and electronic controls. A dressing may be connected to the wound care device for administering topical continuous oxygen therapy and simultaneous negative pressure wound therapy to a wound. A canister or exudate trap may be positioned between the dressing and the vacuum supply port of the vacuum pump to collect and store exudates from the wound. The canister may be combined with the dressing.

Abstract: An assembly comprises an electric consumer, an electric voltage source adapted to power the electric consumer, and user operated actuation means. The electric voltage source is operatable between a first state in which a first voltage is generated and a second state in which a second higher voltage is generated. The user operated actuation means is operatable from a first to a second state and adapted to thereby operate the electric voltage source from the first to the second state, and operatable from the second state to the first state and adapted to thereby operate the electric voltage source from the second to the first state.

Abstract: An ophthalmic laser treatment system and method providing for a liquid optical interface (LOI) with a patient eye surface (PES) using an elliptical ocular suction ring (OSR) is disclosed. A disposable ocular patient interface (OPI) provides for simultaneous differential vacuum mating of the PES, OSR, OPI, and an optical window retainer (OWR). The PES, OSR, OPI, and OWR form an enclosed volume in which liquid may be interjected to cover the PES during laser treatment. A vacuum suction pump (VSP) provides controlled vacuum to the OPI ensuring proper differential vacuum mating (DVM) between the PES, OSR, OPI, and OWR during laser treatment. The OWR connects to a laser objective bracket (LOB) via an ocular force sensor (OFS) and an optical separator bracket (OSB). The OFS senses applied pressure to the PES and provides data to a computerized control device (CCD) that limits applied pressure to the PES during laser treatment.

Abstract: Disclosed herein are several embodiments of medical device packaging, and more particularly to a reduced pressure therapy kit and packaging and methods of using the same in the treatment of wounds. Some embodiments are directed towards packaging including a dressing compartment for storing wound dressings and having use instructions printed thereon, the dressing compartment detachably connected to a pump compartment for storing a sterile pump. After removal of the pump, the pump compartment can be detached from the dressing compartment and discarded. The dressing compartment can be retained together with any additional dressings and the use instructions.