To Or From The Female Reproductory Tract Patents (Class 604/515)
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Patent number: 11839408Abstract: A device may include a flexible tube comprising: a distal end, a proximal tip, the proximal tip comprising a suction line extension being configured for placement in a uterine cavity of a uterus after childbirth, a tube center of the flexible tube; and at least one lumen around the tube center, the at least one lumen comprising a suction line, the suction line being in communication with a source of negative pressure and the suction line extension, the suction line extension being configured for applying the negative pressure to the uterine cavity using the source of the negative pressure thereby causing mechanical hemostasis of bleeding blood vessels of a uterine wall of the uterine cavity. Embodiments include an anchoring mechanism being proximate to the suction line extension along the flexible tube, the anchoring mechanism being configured for maintaining the suction line extension in a desired position within the uterine cavity.Type: GrantFiled: March 16, 2023Date of Patent: December 12, 2023Assignee: Lucie Medical Inc.Inventor: Jennifer West Cobb
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Patent number: 11744920Abstract: An implant for ovarian decline is provided. The implant includes at least an engineered ovarian support cell an extracellular matrix substrate, and a delivery apparatus. In some embodiments, the at least an engineered ovarian support cell includes an engineered granulosa cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered lutein cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered theca cell.Type: GrantFiled: August 12, 2022Date of Patent: September 5, 2023Assignee: Gameto, IncInventors: Dina Radenkovic, Christian Kramme, Martin Varsavsky
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Patent number: 11717325Abstract: A device for managing postpartum hemorrhage is described. The device comprises an intrauterine balloon that may be deflated when inserted into a uterine cavity. The intrauterine balloon may be inflated inside the uterine cavity. The device also comprises a drug delivery vehicle that may be deposited on an outer surface of the intrauterine balloon by a coating technique or an eluting technique. The drug delivery vehicle may release a hemostatic drug into the uterine cavity. The device additionally comprises a cervical barricade that may retain the released hemostatic drug in the uterine cavity. The cervical barricade may be a cone-shaped plug that tapers proximally to conform to a contour of a vagina. The device further comprises a catheter that may be used to inflate the intrauterine balloon, deflate the intrauterine balloon, and support the cervical barricade.Type: GrantFiled: December 3, 2017Date of Patent: August 8, 2023Inventor: Nasser Kamal Abd Elaal
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Patent number: 11602269Abstract: A falloposcope intended for use with a hysteroscope to access, image, and collect samples from a patient's fallopian tube includes a cannula having an angled tip oriented to engage a fallopian tube os when the cannula is transcervically introduced to a patient's uterus through the hysteroscope. The catheter has a distal viewing tip configured to be advanced from a distal end of the cannula into the patient's uterus through a cervical os. A viewing chamber has a wide proximal end attached to the distal viewing tip of the catheter, and the viewing chamber is at least partially transparent and typically tapers in a distal direction to provide a clear viewing zone for the endoscope as well as atraumatic advancement into the fallopian tube.Type: GrantFiled: May 26, 2020Date of Patent: March 14, 2023Assignee: FemDX Medsystems, Inc.Inventors: Albert K. Chin, Pei-Jie Cao
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Patent number: 11278641Abstract: Disclosed are methods of delivering an agent to the lumen of the vas deferens under guidance of ultrasound imaging. The methods include vas-occlusive contraception in which the vas deferens is non-surgically isolated and an occlusive substance is percutaneously administered into the lumen of the vas deferens under ultrasound. Also disclosed are methods of reversal of vas-occlusive contraception and methods of delivering an agent to the lumen of the vas deferens. Also disclosed are compositions for use in the methods of the invention.Type: GrantFiled: October 29, 2018Date of Patent: March 22, 2022Assignee: University of Virginia Patent FoundationInventors: John C. Herr, Alexander L. Klibanov, Kevin Simon Eisenfrats
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Patent number: 11141194Abstract: The uterine hemostatic balloon unit includes a tube, a hemostatic balloon, a connector disposed in the tube, and a cap to be detachably attached to a proximal end portion of the tube. The tube has a drain channel for draining uterine blood outward and a water supply channel communicating with the hemostatic balloon. The connector has a drain terminal communicating with the drain channel and disposed in a proximal end portion of the tube, a flexible water supply tube communicating with the water supply channel and extending by being bifurcated outward of the tube, and a water supply terminal communicating with the water supply tube. The cap has an accommodating portion capable of accommodating the water supply terminal along a length direction of the drain terminal. The accommodating portion is open in a direction orthogonal to the length direction of the drain terminal.Type: GrantFiled: June 12, 2019Date of Patent: October 12, 2021Assignee: ATOM MEDICAL CORPORATIONInventors: Keisuke Wakabayashi, Shinichi Kobayashi, Tatsuhiko Seki, Ichiro Matsubara
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Patent number: 10959757Abstract: A kit having instructions for use for performing uterine lavage in a female patient includes a uterine lavage catheter configured for insertion into a woman's uterus to remove viable blastocysts from the uterus, and one or more first containers having a sufficient dosage amount of a GnRH antagonist to cause desynchronization of the endometrium of the patient prior to, during and/or following recovery of viable blastocysts from the uterus.Type: GrantFiled: March 1, 2018Date of Patent: March 30, 2021Assignee: Previvo Genetics, Inc.Inventors: Sandra Ann Carson, John E. Buster, Moses Cesario, Steven Paul Woodard
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Patent number: 10722298Abstract: An endocervical seal has a sleeve with a passageway for receiving an intrauterine interventional or diagnostic tool. The sleeve has a coaxially disposed outer balloon with a distal portion configured to inflate in a cervical os and a proximal portion configured to inflate in a cervical canal.Type: GrantFiled: July 18, 2016Date of Patent: July 28, 2020Assignee: Minerva Surgical, Inc.Inventor: Eugene Skalnyi
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Patent number: 10624727Abstract: The present invention discloses a biomechanically compatible implant, wherein arbitrary selectable discrete locations of the implant are defined to exhibit biomechanical characteristics in accordance with biomechanical characteristics at arbitrary selectable discrete locations of a bodily tissue where the respective arbitrary selectable discrete locations of the implant are configured to be attached. The implant may be configured to repair prolapse in an embodiment. In another embodiment, the implant may be configured to repair urinary incontinence. The present invention further discloses a device for generating a biomechanical characteristics pattern of the bodily tissue and the implant. The present invention further discloses a system for designing and fabricating the biomechanically compatible implant.Type: GrantFiled: June 25, 2015Date of Patent: April 21, 2020Assignee: IPENGINE MANAGEMENT (INDIA) PRIVATE LIMITEDInventors: Mohammad Sufyan, Rajeev Malhotra
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Patent number: 10188400Abstract: An intraluminal occluding catheter and method for preventing the loss of gas insufflation from a physiological lumen during a medical procedure is presented. The intraluminal occluding catheter is generally comprised of a catheter shaft having a flexible balloon affixed on a distal intraluminal end and a plurality of independent channels extending through the catheter shaft from the external proximal end to the distal intraluminal end. Once inserted into a physiological lumen such as the bowel, the intraluminal occluding catheter controls the loss of insufflation proximally thereby improving the safety and efficiency of TAMIS as well as allowing for more controlled gas exchange to clear smoke or vapor.Type: GrantFiled: August 26, 2014Date of Patent: January 29, 2019Assignee: University of South FloridaInventors: Jaime Eduardo Sanchez, Michael Eric Dolberg, Sowsan Heidar Rasheid
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Patent number: 9566050Abstract: An apparatus for use in connection with an endoscopic surgery comprises an elongated body adapted to be placed at least partially in the vagina of a female patient partially passing through the wall of the vagina such that an end portion of said elongated element is introduced into rectouterine pouch; the elongated body comprises at least an attachment means for accommodating at least a part of at least a surgical instrument comprising an end portion adapted to be received inside the vagina, the surgical instrument and the apparatus are movable to each other. An endobag having an elongated port is provided through the vagina into the pelvis.Type: GrantFiled: August 1, 2011Date of Patent: February 14, 2017Inventor: Tamer A Seckin
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Patent number: 9566267Abstract: Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vaginal infection, while further exhibiting at least one additional function selected from the group dealing with non-hormonal contraception, management of sexually transmitted diseases, viral infections, and retroviral infections as well as the treatment of cervical cancer.Type: GrantFiled: May 18, 2015Date of Patent: February 14, 2017Assignee: Poly-Med, Inc.Inventors: Shalaby W. Shalaby, Georgios T. Hilas
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Patent number: 9216037Abstract: A device for recovering one or more blastocysts from the uterus of a human includes an outer guide member for insertion into a cervical canal of the human. The outer guide member includes a distal portion with an activatable seal for isolating the uterus from the external environment and defines a lumen having a longitudinal axis. The device also includes an inner catheter located within the lumen and slidable along the longitudinal axis of the lumen relative to the outer guide member. The inner catheter has a distal tip positionable distally of the seal to extend into the uterus and includes a fluid delivery lumen terminating at a distal fluid delivery port for delivering fluid into the uterus. The device defines a distal suction port for aspirating fluid and entrained blastocysts from the uterus. The distal fluid delivery port and the distal suction port are arranged such that, in use, fluid delivered from the distal fluid delivery port travels through the distal suction port to the uterus.Type: GrantFiled: June 21, 2013Date of Patent: December 22, 2015Assignee: Previvo Genetics, LLCInventors: John E. Buster, Moses Cesario, Steven Paul Woodard
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Patent number: 9125687Abstract: According to the present invention, an amniotic fluid collector is configured so as to be inserted and positioned inside the vagina of a birthing mother in order to collect amniotic fluid from the womb of the birthing mother. In particular, the amniotic fluid collector of the present invention comprises: a receiving member, in the side of which an opening is defined, which is inserted into the vagina of the birthing mother and which has a receptacle defined therein for receiving the amniotic fluid; and a positioning portion for positioning the receiving member inside the vagina. Thus, the effects of alleviating pain and psychological anxiety of a birthing mother and eliminating the danger of the occurrence of complications can be achieved, as well as those of easily and smoothly collecting amniotic fluid from the womb of the birthing mother.Type: GrantFiled: April 5, 2011Date of Patent: September 8, 2015Assignee: SNU R&DB FOUNDATIONInventors: Bo Hyun Yoon, Chan Wook Park, Seung Mi Lee, Joong Shin Park
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Patent number: 9101391Abstract: Everting balloon systems and methods for using the same are disclosed herein. The systems can be configured to access and dilate body lumen and cavities. For example, the systems can be used to dilate the cervix and access the uterine cavity. The systems can also be used to occlude the cervix. The systems can also be used to occlude the urethra.Type: GrantFiled: October 27, 2014Date of Patent: August 11, 2015Assignee: Cross Bay Medical, Inc.Inventors: Steven R. Bacich, Piush Vidyarthi, Matt Yurek, Jack Greelis
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Publication number: 20150141963Abstract: A device for chemical endometrial ablation comprising an outer tube, a moveable cervical collar surrounding a portion of the outer tube and located near the distal end of the outer tube, an inner tube movable in a distal-proximal direction within the lumen of the outer tube, a porous and/or sponge-like material on the distal end of the inner tube within the lumen of the distal end of the outer tube having a size, shape, and expandability so that when the distal end of the inner tube within the distal end of the outer tube is moved in a distal direction in relation to the outer tube, the porous and/or sponge-like material expands to the approximate size of a uterus so as to contact the endometrium, a source of cauterizing agent, and means to cause the cauterizing agent to flow through the lumen of the inner tube onto the porous and/or sponge-like material.Type: ApplicationFiled: June 13, 2013Publication date: May 21, 2015Inventor: Steven R. Goldstein
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Patent number: 9034053Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.Type: GrantFiled: November 24, 2012Date of Patent: May 19, 2015Assignee: FEMASYS INC.Inventors: Kathy Lee-Sepsick, Lani L. L. Paxton, Jeffrey A. Marcus, Stephen N. Williams
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Patent number: 9017310Abstract: Devices and methods for transmucosal drug delivery are provided. A device includes a housing configured for intralumenal deployment into a human or animal subject; a drug-dispensing portion which contains at least one drug; and a plurality of microneedles extending, or being extendable from, the housing, the plurality of microneedles being configured to disrupt at least one region of a mucosal barrier adjacent the housing at a selected time after being intralumenally deployed in the human or animal subject. The device is operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the plurality of microneedles.Type: GrantFiled: October 8, 2009Date of Patent: April 28, 2015Assignee: Palo Alto Research Center IncorporatedInventors: Scott Uhland, Eric Peeters
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Patent number: 9014799Abstract: Intralumenal devices and methods are provided for transmucosal drug delivery. The device may comprise a housing configured for intralumenal deployment into a human or animal subject; a drug-dispensing portion which contains at least one drug; and an electrically-actuatable portion configured to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the electrically-actuatable portion.Type: GrantFiled: October 8, 2009Date of Patent: April 21, 2015Assignee: Palo Alto Research Center IncorporatedInventors: Scott Uhland, Eric Peeters, Serena Wong
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Publication number: 20150105751Abstract: Devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs.Type: ApplicationFiled: December 19, 2014Publication date: April 16, 2015Inventors: Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn
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Publication number: 20150065997Abstract: Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.Type: ApplicationFiled: November 10, 2014Publication date: March 5, 2015Inventors: Scott Uhland, Eric Peeters, Hussain Fatakdawala
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Publication number: 20140378948Abstract: Apparatus and methods for inserting a medicament into a body cavity are described. The apparatus comprises an elongate tube with a plunger rod therein. The plunger rod has at least one projection which cooperatively interacts or engages with at least one discontinuity on the inside of the elongate tube so that proximal movement of the plunger rod with respect to the elongate tube expels the medicament into the body cavity.Type: ApplicationFiled: June 19, 2013Publication date: December 25, 2014Inventors: Jamelo J. Mellejor, Sanjeev K. Gupta, Dipen Desai
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Patent number: 8882748Abstract: Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.Type: GrantFiled: October 8, 2009Date of Patent: November 11, 2014Assignee: Palo Alto Research Center IncorporatedInventors: Scott Uhland, Eric Peeters, Hussain Fatakdawala
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Publication number: 20140316214Abstract: Devices and methods for performing in vitro fertilization (“IVF”) and maximizing successful fertilization rates by optimizing the fluid flow conditions under which zygotes are transferred from growth medium to the uterine wall. The apparatus has a control unit with an external port and an internal pump for creating positive and negative fluid pressure at the port. A flexible extension hose connects the port to an inter-uterine catheter assembly. The catheter assembly has an inner catheter and an outer sheath surrounding the inner catheter. The control unit includes a programmable microprocessor that accepts input commands and controls operation of the pump. Optionally, the control unit has remote control means for activating, de-activating, and reversing the flow of the pump. The control unit can be programmed to repeatedly provide the same aspiration and expulsion flow conditions through the catheter assembly.Type: ApplicationFiled: December 18, 2013Publication date: October 23, 2014Inventors: Michael E. Drummond, Nicholas M. DiTrolio
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Publication number: 20140296833Abstract: An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.Type: ApplicationFiled: November 6, 2013Publication date: October 2, 2014Applicant: Merck Sharp & Dohme B.V.Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
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Publication number: 20140296834Abstract: The present invention provides for a drug delivery device. The device can comprise at least one core with a first active pharmaceutical ingredient (API), coated with a first layer that is permeable or semi-permeable to the API, coated with a second layer that is impermeable to the API, and having a delivery window to allow passage of the API through the device and into body fluids or tissues. The device can also have a wicking material to modify the rate of transport of the API into the body fluid or tissues.Type: ApplicationFiled: June 6, 2012Publication date: October 2, 2014Applicant: OAKCREST INSTITUTE OF SCIENCEInventors: John A. Moss, Thomas J. Smith, Marc M. Baum
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Patent number: 8840626Abstract: Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. The system is configured to permit simultaneous tissue cutting and removal from a target site. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic.Type: GrantFiled: September 7, 2007Date of Patent: September 23, 2014Assignee: Hologic, Inc.Inventors: Ronald D. Adams, William H. Gruber, Kevin G. Connors, Geoffrey B. Pardo, James Daniel Cole, J. Christopher Flaherty
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Patent number: 8840625Abstract: Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. An access sheath is provided with at least one lumen, and a lens attached thereto. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic.Type: GrantFiled: September 7, 2007Date of Patent: September 23, 2014Assignee: Hologic, Inc.Inventors: Ronald D. Adams, William H. Gruber, Kevin G. Connors, Geoffrey B. Pardo, James Daniel Cole, J. Christopher Flaherty
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Publication number: 20140271919Abstract: Copper ion treatments and methods of treatment are provided to treat various body conditions affecting the genital and/or rectal areas. The copper ion treatments contain a copper ion-containing solution which, as a result of the copper ions contacting anatomical tissue of the vagina, the rectal canal and/or the external genital or rectal areas, brings about local and systemic therapeutic effects. The copper ion treatments and methods for treating conditions affecting the genital and/or rectal areas involve the use of tampons, suppositories, lotions, creams, gels, foams and solutions, each containing a copper ion-containing solution. The tampon bodies and the copper ion lotions, creams, gels and foams may be delivered into the vagina, and the suppositories can be delivered into the vagina or into the rectal canal. The copper ion lotions, creams, gels, foams and solutions may also be topically applied to the external genital and/or rectal areas.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventors: Chun Lim Abbott, Dominic C. Abbott
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Patent number: 8834487Abstract: Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. Patient benefit is achieved through improved outcomes, reduced pain, especially peri-procedural pain, and reduced recovery times. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic. Distension is achieved mechanically, rather than with liquid distension media, thereby eliminating the risk of intravasation.Type: GrantFiled: July 23, 2010Date of Patent: September 16, 2014Assignee: Hologic, Inc.Inventors: William H. Gruber, Ronald D. Adams, Kevin G. Connors, Geoffrey B. Pardo, James Daniel Cole, J. Christopher Flaherty
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Publication number: 20140228813Abstract: A method of treating pelvic organ prolapse in a patient is provided. The method includes inserting a support device into a natural vaginal opening of the patient and placing the support device in contact with an interior apical portion of a vagina. The method additionally includes implanting an anchor in the patient and attaching a first end of the anchor to the support device and attaching a second end of the anchor to one of a sacrum and a ligament of the patient.Type: ApplicationFiled: August 22, 2013Publication date: August 14, 2014Applicant: Coloplast A/SInventor: Rachael Anne Bergstrom Crabb
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Publication number: 20140207112Abstract: A collapsible squeeze bottle suitable for use as a portable personal hygienic washing system provides vigorous cleansing action and can attain a compact configuration conducive to discreet concealment. The squeeze bottle includes non-collapsible top and bottom sections, and a central collapsible section having a plurality of pleats, a spout extending from the top section, and a perforated cap at the terminus of the spout.Type: ApplicationFiled: January 15, 2014Publication date: July 24, 2014Inventor: Rosemarie Hale
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Publication number: 20140200553Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.Type: ApplicationFiled: January 15, 2013Publication date: July 17, 2014Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: David Mathew Johnson, Martin Sheridan, Scott A. Uhland, Ramkumar Abhishek, Eric Peeters, Timothy J. Curley, Felicia Linn, Philipp H. Schmaelzle
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Patent number: 8777912Abstract: A waste management system includes a waste transport device and a waste collection device. The waste management system may include a securement device for maintaining the position of the waste transport device following insertion. The waste transport device may include a modular medication delivery apparatus with a disposable delivery device for delivering medication to the patient following insertion of the waste transport device.Type: GrantFiled: July 22, 2008Date of Patent: July 15, 2014Assignee: C. R. Bard, Inc.Inventors: Vasu Nishtala, Jeffrey Francis Kline, Ronald L. Bracken
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Publication number: 20140107481Abstract: Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a diagnostic or therapeutic composition, or ports for infusing a diagnostic or therapeutic composition prior to, during or following an interventional procedure are provided.Type: ApplicationFiled: December 18, 2013Publication date: April 17, 2014Applicant: MEDRAD, INC.Inventor: Edward I. Wulfman
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Patent number: 8695605Abstract: A device for occluding the fallopian tube including a wire composed of a shape memory material and an outer material encapsulating at least a portion of the wire. The device has a first elongated configuration for delivery and a second configuration for placement. In the second configuration, the wire moves toward its shape memory position and has a U-shape defined by a curved portion and first and second leg portions extending from the curved portion, the first and second leg portions extending downwardly from the curved portion and laterally outwardly.Type: GrantFiled: July 5, 2012Date of Patent: April 15, 2014Assignee: Rex Medical, L.P.Inventor: James F. McGuckin, Jr.
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Patent number: 8696615Abstract: An apparatus for transferring an ovum from a follicle with a double lumen needle having at the distal needle end an aspiration lumen for removing an ovum from a follicle and a flushing lumen, the double lumen needle including an outer tube with an internally located inner tube that extends over at least part of the length of the outer tube, one of the lumens being bounded by the inner surface of the inner tube and the other of the two lumens by the space between the outer surface of the inner tube and the inner surface of the outer tube, and a connector having an outlet at a second connector end for discharging the flushing fluid with possibly an ovum to the exterior and having a channel that connects the outlet with the aspiration lumen and a flushing inlet for supplying the flushing fluid, such that the two fluid pathways within the connector and the double lumen needle are separated from each other, and the inner tube comprises a deformable material.Type: GrantFiled: October 23, 2009Date of Patent: April 15, 2014Assignee: GynotecInventor: Josephus E. J. M. Berbers
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Publication number: 20140088486Abstract: Devices and methods are provided for drug delivery. The device may include a housing having a first compartment containing a drug in a dry, solid form, a second compartment containing a liquid carrier for the drug, and an expansion member located within or adjacent to the first or second compartment. The second compartment may be fluidly connectable to the first compartment by a rupturable barrier or mechanical valve. The device may also include an actuation system configured to expand the expansion member to rupture the rupturable barrier or open the mechanical valve and permit the liquid carrier to flow into the first compartment and mix with the drug to form a reconstituted drug solution.Type: ApplicationFiled: September 27, 2012Publication date: March 27, 2014Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: Scott A. Uhland, Felicia Linn, Michael I. Recht
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Publication number: 20140074067Abstract: The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.Type: ApplicationFiled: November 11, 2011Publication date: March 13, 2014Inventors: Patrick F. Kiser, R. Tyler McCabe, Margaret N. Kiser, Theodore Henry Albright
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Publication number: 20140039639Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.Type: ApplicationFiled: November 24, 2012Publication date: February 6, 2014Applicant: Femasys Inc.Inventor: Femasys Inc.
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Patent number: 8641597Abstract: A new, quick, simple, efficient, safe, and reproducible surgical technique for the treatment of female urinary incontinence, in which the posterior urethra is suspended using a tape passed through the obturator orifices from inside (underneath the urethra) to outside (thigh folds). A variety of specifically designed surgical instruments are utilized to perform this operative procedure.Type: GrantFiled: August 12, 2009Date of Patent: February 4, 2014Assignees: Oniversite de Liège, Centre Hospitalier Universitaire de LiegeInventor: Jean De Leval
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Publication number: 20140024934Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for diagnosing or treating conduits. The delivery system is positioned to allow for placement of the composition into the body conduit. Use of delivery systems, methods and devices for delivering to a body conduit are also included.Type: ApplicationFiled: September 19, 2013Publication date: January 23, 2014Applicant: Femasys, Inc.Inventor: Kathy Lee-Sepsick
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Patent number: 8616213Abstract: An earplug insertion device can include a housing that is configured to hold a first earplug and a second earplug. The device can also include an ejection mechanism that can be configured to respond to a first user force by ejecting the first earplug from the device in a first ejection motion. The ejection mechanism can also being configured to respond to a second user force by ejecting the second earplug from the device in a second ejection motion.Type: GrantFiled: November 11, 2008Date of Patent: December 31, 2013Assignee: J3 Group, LLCInventors: Shawn Matthew Johnson, John Matthew Johnson, Joshua Ingvald Kenneth Johnson
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Patent number: 8617100Abstract: A device for delivery of a foamable composition to a body cavity includes a pressurized composition reservoir; a hollow body having a longitudinally extending wall and having at least one aperture provided through a wall of said body, the proximal end in fluid communication with the reservoir for receiving a foamable composition from said composition reservoir; and an actuator operatively connected to the composition reservoir for effecting release of a foamable composition from said composition reservoir into a body cavity through said hollow body; wherein said body has a length less than about 125 mm and internal diameter in the range of about 1.5 mm to about 3.5 mm, wherein said length and internal diameter are selected to provide a delivery of at least about 70% of the foamable composition during operation. The foam delivery device can have multiple apertures.Type: GrantFiled: September 4, 2008Date of Patent: December 31, 2013Assignee: Foamix Ltd.Inventors: Meir Eini, David Schuz, Helen Shifrin, Yohan Hazot, Dov Tamarkin
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Publication number: 20130345678Abstract: A method, medicated feminine sanitary products and compositions for reducing menstrual blood loss in a female are provided. The method comprises delivering an active agent to the uterine cavity by administering intravaginally to the female a therapeutically effective amount of the active agent on a medicated feminine sanitary product during menstrual bleeding, wherein the medicated feminine sanitary product is routinely utilized to absorb the menstrual flow, wherein the active agent is incorporated in the medicated feminine sanitary product as a pharmaceutically acceptable composition, the active agent is any of an antifibrinolytic and a hemostatic agent.Type: ApplicationFiled: August 22, 2013Publication date: December 26, 2013Applicant: ARSTAT Inc.Inventor: Arkady RUBIN
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Patent number: 8597289Abstract: A device for sealing a cervical opening includes a support structure, and a seal coupled to the support structure, the seal having a surface for abutting against tissue next to the cervical opening, wherein the seal is tiltable relative to the support structure. A device for sealing a cervical opening includes a support structure, and a member coupled to the support structure, wherein the member is inflatable to create a seal for abutting against cervical tissue. A device for sealing a cervical opening includes a seal having a surface for contacting tissue next to the cervical opening, an opening formed on the surface of the seal, and a vacuum port, wherein the opening is in fluid communication with the vacuum port.Type: GrantFiled: January 29, 2010Date of Patent: December 3, 2013Assignee: Cytyc CorporationInventors: Russell K. Layton, Jr., Lionel Stewart MacLean, David Freed, Brian Hanley
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Patent number: 8568385Abstract: A method of treating tissue comprises introducing into a hollow organ a support device and, after insertion, arranging the support device into a non-yielding configuration substantially filling the hollow organ and substantially preventing walls of the hollow organ from moving inward in combination with inducing contraction of the hollow organ around the support device to cut off blood flow through at least a portion of the walls of the hollow organ and removing the support device after blood flow has been cut off for a predetermined time.Type: GrantFiled: September 9, 2008Date of Patent: October 29, 2013Assignee: Boston Scientific Scimed, Inc.Inventor: Jon T. McIntyre
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Publication number: 20130225977Abstract: The present invention comprises systems, methods and devices for the delivery of visualizable or treatment compositions or therapeutic agents comprising device elements for diagnosis and/or treatment of conduits. A delivery system comprising an introducer shaft having at least one exit port sad at least one delivery catheter tor placement of compositions into the conduit, such as a fallopian tube.Type: ApplicationFiled: November 25, 2012Publication date: August 29, 2013Applicant: Femasys Inc.Inventor: Femasys Inc.
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Publication number: 20130211384Abstract: A medical composition including a chemotherapeutic medication or a targeted therapy medication is used in a human female patient for the treatment of a disease selected in the group comprising cervical cancer, cervical intraepithelial neoplasia (CIN), human papillomavirus (HPV) infection of the female genital system; the chemotherapeutic agent or targeted therapy medication is locally delivered directly to cervix of a female genital system by an implanted medical device including a stem to be implanted in the cervix. The stem has a drug carrying layer including the medical composition. A process for the treatment of the above diseases is also disclosed.Type: ApplicationFiled: July 28, 2010Publication date: August 15, 2013Applicant: FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORIInventor: Francesco Raspagliesi
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Publication number: 20130144264Abstract: Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.Type: ApplicationFiled: January 30, 2013Publication date: June 6, 2013Inventors: Shalaby W. Shalaby, Kenneth David Gray, Georgios T. Hilas