Method Patents (Class 604/500)
  • Patent number: 10779870
    Abstract: A curved inflatable bone tamp includes an outer shaft defining a passageway. An inner shaft is positioned within the passageway. The inner shaft extends between opposite first and second end. The inner shaft defines a lumen. The inner shaft is curved between the first end and the second end. A first leg of a balloon is coupled to the outer shaft and a second leg of the balloon is coupled to the inner shaft such that a material can flow through the lumen and into the balloon to inflate the balloon. The balloon includes a wall having a variable thickness between the legs when the balloon is uninflated and a uniform thickness between the legs when the balloon is inflated. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: September 22, 2020
    Assignee: MEDTRONIC HOLDING COMPANY SARL
    Inventors: Mojan Goshayeshgar, Samuel V. Bolosan
  • Patent number: 10772636
    Abstract: Atrial appendage occlusion systems are provided, such systems including a first device and a second device. The first device has a first tube sized and shaped for insertion into the heart and a balloon coupled thereto. The second device has a second tube sized and shaped for insertion into a pericardial space surrounding the heart, and has a lumen extending at least partially from a second tube distal end to a second tube proximal end. The second device also includes a loop sized and shaped to fit at least partially within the lumen of the second tube, with the loop configured for protraction from the second tube distal end and for placement, and to be tightened and secured around, the atrial appendage.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: September 15, 2020
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 10773009
    Abstract: A method and system for infusing medical liquid with gasses, the system comprising a gas source, a vacuum pump, a temperature-controlled container including a fluid reservoir coupled to the gas source and the vacuum pump, a heating and cooling system, and a sonicator, and a controller configured to de-gas a liquid in the fluid reservoir by activating the vacuum pump, re-gas the liquid in the fluid reservoir by releasing gas from the gas source to the fluid reservoir via a first fluid line, and deliver the re-gassed liquid from the fluid reservoir to a catheter via a second fluid line.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: September 15, 2020
    Assignee: TRANSLUMINAL SYSTEMS, LLC
    Inventors: John Pile-Spellman, Jae H. Choi
  • Patent number: 10758155
    Abstract: A method of obtaining information about the position and/or orientation of a magnetic component relatively to a magnetometric detector, the magnetic component and the magnetometric detector being moveable independently from each other relatively to a static secondary magnetic field, the method comprising the steps of: measuring in the presence of the combination of both the magnetic field of the magnetic component and the static secondary magnetic field essentially simultaneously the strength and/or orientation of a magnetic field at at least a first position and a second position spatially associated with the magnetometric detector, the second position being distanced from the first position; and combining the results of the measurements to computationally eliminate the effect of the secondary magnetic field and derive the information about the position and/or orientation of the magnetic component.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: September 1, 2020
    Assignee: eZono AG
    Inventors: Rolf Henkel, Eliseo Ventura Sobrino Patino, Robert Von Offenberg Sweeney, Allan Dunbar
  • Patent number: 10751203
    Abstract: Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: August 25, 2020
    Assignee: Healionics Corporation
    Inventors: Andrew J. Marshall, Brandt Scanlan, Max Maginness, Adrienne Oda, Michael J. Connolly, Chad MacDonald
  • Patent number: 10737060
    Abstract: A hub assembly for connection to a medical device having a built in strain relief. The hub assembly may comprise a hub body having a proximal end and a distal end. A lumen may extend from the proximal end to the distal end of the hub body. The distal end of the hub body may have a rounded surface. The rounded surface may have a radius of curvature of greater than 1 millimeter.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: August 11, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Ajay Gupta, David Raab, Mark S. Smith, Ken Fredrikson
  • Patent number: 10722257
    Abstract: Devices for removing clot material from a blood vessel lumen and associated systems and methods are disclosed herein. A clot retrieving device may include, for example, an elongated shaft, a capture structure having a proximal region coupled to the distal zone of the elongated shaft, a cover, and a connector coupling the cover to the distal zone of the elongated shaft. The device may further include a jacket at least partially over the proximal terminus of the connector and a portion of the filaments protruding from the connector.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: July 28, 2020
    Assignee: COVIDIEN LP
    Inventors: Erik Skillrud, Daniel Deen, Evan Epstein
  • Patent number: 10716894
    Abstract: The present invention relates to a medicinal fluid flow rate control apparatus and a medicinal fluid injector including the medicinal fluid flow control apparatus. The medicinal fluid flow rate control apparatus includes: an operation knob being able to be turned; a plurality of medicinal fluid delivery lines each having an elastically deformable tube and arranged such that the tubes are arranged at different heights at a side from the operation knob; a tube support member supporting the tubes; a medicinal fluid converger converging medicinal fluids from the medicinal fluid delivery lines into one stream; and a pipe switch selectively pressing or releasing the tubes to open or block all of the medicinal fluid delivery lines or block some of the medicinal fluid delivery lines, depending on a rotational angle of the operation knob.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: July 21, 2020
    Inventor: Woo Suk Lee
  • Patent number: 10716891
    Abstract: An implantable system for delivering fluids, such as drugs, to one or more anatomical structures in a patient's (i.e., human or animal) body. A number of medical conditions require continual and/or periodic administration of fluids (e.g., drugs) to target regions (e.g., anatomic organs) of the body. Accessibility to those target regions might be limited technically for ex. and not limited to: frequent endoscopic, radiologically guided or surgical approaches. The system delivers the fluid needed in a continual or intermittent fashion to the target region. It controls the amount of fluid delivered to the target region and measures the intended physiologic effect of the fluid delivered.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: July 21, 2020
    Assignee: ISaab Innovations LLC
    Inventor: Ihab Saab
  • Patent number: 10705491
    Abstract: A hydraulic system having a hydraulic device and at least one external database is provided. The hydraulic device comprises at least one hydraulic component, a control electronics having a memory to control the hydraulic component, and an identification element assigned to the hydraulic component. Specific parameters for the hydraulic component are stored in the external database, and the hydraulic component can be clearly identified by a configuration means via the identification element. The configuration means can be connected to the control electronics and the external database to access the specific parameters so that these can be transferred to the memory of the control electronics by means of the configuration means. Further, the disclosure relates to a method for parameterizing control electronics of a hydraulic device of a hydraulic system as well as an arithmetic unit for compiling a program code for the operation of a hydraulic assembly with several components.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: July 7, 2020
    Assignee: HAWE HYDRAULIK SE
    Inventors: Johannes Glaser, Stanley Buchert, Paul Siegel, Timotheus Wieringa
  • Patent number: 10702274
    Abstract: The present teachings provide methods for resizing, reducing, and closing left atrial appendage. Specifically, a percutaneous trans-septal access is first established from outside the body to a patient's LAA. At least two tissue anchors are then implanted inside the LAA chamber and along the tissue wall. At least one anchor is implanted near the opening of the LAA camber. Both tissue anchors are pulled together so that the wall of the LAA chamber collapse. The LAA chamber is therefore resized, reduced, and/or closed off completely. This closure method and system could be used alone in closing LAA chamber. This closure method and system could also be used in addition to other treatment mechanisms, such as filling the LAA chamber with space-filling material, then closing off its opening.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: July 7, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Adam Groothuis, Steven D. Cahalane
  • Patent number: 10687879
    Abstract: A bone material dispensing device is provided. The bone material dispensing device comprises a housing having a proximal end, a distal end, and a longitudinal axis. The proximal end has a first opening and the distal end has a second opening. The first opening and the second opening are configured to slidably receive at least a portion of a plunger. A tubular member is provided that is pivotably connected to the housing and is configured for lateral movement relative to the longitudinal axis of the housing. The tubular member comprises a proximal opening, a distal opening and a channel disposed therebetween. The proximal opening, the distal opening and the channel of the tubular member are configured to receive at least the portion of the plunger. The tubular member is movable in a first position to align the proximal opening of the tubular member with the second opening of the housing to allow the tubular member to receive at least the portion of the plunger to dispense the bone material.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: June 23, 2020
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Jonathan M. Dewey, Ralph D. Goosby, Daniel A. Shimko, Erick Vasquez
  • Patent number: 10682467
    Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a dose selector operable to set a dose by rotation relative to the housing, a number sleeve arranged within the housing, a drive sleeve which is rotationally constrained to the housing during dose setting and dose correcting and which is rotatable relative to the housing during dose dispensing, a piston rod coupled to the housing and to the drive sleeve a drive spring arranged between the housing and the number sleeve, and a ratchet operatively arranged between the drive sleeve and the number sleeve. According to the disclosure the ratchet comprises at least one clicker arm of one of the number sleeve and the drive sleeve and ratchet teeth of the other of the number sleeve and the drive sleeve.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: June 16, 2020
    Assignee: Sanofi
    Inventors: Richard James Vincent Avery, Matthew Jones
  • Patent number: 10673433
    Abstract: Provided are a control switch mechanism, a trigger switch, and an electric tool, having vibration resistance and durability and capable of preventing malfunction. The control switch mechanism (20) includes an optical sensor (21) having a light emitting element (21a) and a light receiving element (21b), and a reflector (22) that increases or decreases an amount of light received by the light receiving element (21b). An increase and a decrease in output of an operation device are controlled along with an increase and decrease in amount of light received by the light receiving element (21b) due to relative movement between the optical sensor (21) and the reflector (22).
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: June 2, 2020
    Assignee: OMRON Corporation
    Inventors: Minoru Kobayashi, Yusaku Yamasaki, Koji Omori, Jeongho Baik
  • Patent number: 10639405
    Abstract: Provided is an adsorbent for removing histones from a liquid derived from a living-organism, including a water-insoluble carrier and a biocompatible polymer. The carrier has activated carbon, a polyester, a polysulfone, or a cationic functional group. Also provided is a device for purifying a liquid derived from a living-organism to remove histones from a liquid derived from a living-organism, which has a housing equipped with an inlet and an outlet for the liquid derived from the living-organism and the above-described adsorbent housed in the housing. The liquid derived from the living-organism is moved through the housing of device for purifying the liquid derived from the living-organism to remove histones from the liquid derived from the living-organism.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: May 5, 2020
    Assignee: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Kentaro Kiriyama, Satoru Inoue, Yoshihiro Hatanaka
  • Patent number: 10583248
    Abstract: A droplet measurement system is provided with: an imaging device placed to locate a tip part of a nozzle and the entire liquid hanging down from the nozzle within a field of view; an image generation unit that generates a plurality of images that capture the state in which droplets are dripping down from the nozzle based on image data output from the imaging device; a dripping detection unit that detects, from the plurality of images, a dripping-detected image in which the fact that a droplet has departed from the nozzle is detected; and a volume calculation unit that calculates the volume of the droplet based, at least, on an image-before-dripping, which is generated a predetermined number of frames before the dripping-detected image and capturing liquid hanging down from the nozzle and on a reference image that captures at least the tip part of the nozzle.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: March 10, 2020
    Assignees: ICOMES LAB, Co., Ltd., IGUNOSS, Inc.
    Inventors: Isao Ohwada, Harumi Sangawa, Masatsugu Nitagai, Keiji Katano, Tadataka Kamiyama, Naoyuki Odashima
  • Patent number: 10576203
    Abstract: An infusion device includes a pump device having a housing and a flexible wall section together forming a channel extending along a channel length between first and second ends. An actuation device locally depresses the flexible wall section in a vertical direction, and is displaceable along the vertical direction. To pump a fluid through the channel, the actuation device is actuated to depress the flexible wall section at a depression location, the depression location during one pump cycle moving along the channel length. To calibrate the infusion device, the position of the actuation device along the vertical direction during one pump cycle is measured to obtain a measured profile, a difference between the measured profile and a prestored nominal profile is formed to obtain a difference profile, and from the difference profile a characteristic value for correcting and/or checking the pump operation of the infusion device is calculated.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: March 3, 2020
    Assignee: Fresenius Vial SAS
    Inventors: Barbara Amon, Michael Becker
  • Patent number: 10560666
    Abstract: An imaging system that includes a camera mourned on an aerial platform, for example a balloon, allows a user to increase the longevity of the camera's battery by remote control. A user may capture imagery at a time scale of interest and desired power consumption by adjusting parameters for image capture by the camera. A user may adjust a time to capture an image, a time to capture a video, or a number of cycles per time period to capture one or more images as the aerial platform moves in a region of interest to change power consumption for imaging. The system also provides imaging alignment to account for unwanted movement of the aerial platform when moved in the region of interest. Additionally, a mounting device is provided that is simple and inexpensive, and that allows a camera to remain positioned in a desired position relative to the ground.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: February 11, 2020
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Ranveer Chandra, Manohar Swaminathan, Vasuki Narasimha Swamy, Zerina Kapetanovic, Deepak Vasisht, Akshit Kumar, Anirudh Badam, Gireeja Ranade, Sudipta Sinha, Rohit Patil
  • Patent number: 10549037
    Abstract: Some embodiments a glucagon administration system can provide a suggested glucagon dosage based on one or more particular parameters (e.g., the user's recent blood glucose characteristics, a glucagon sensitivity value of the user, and other parameters). In some circumstances, the glucagon administration system can receive information indicative of the user's blood glucose level and suggest a glucagon dosage that is at least partially dependent upon a previously stored glucagon sensitivity for the user.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: February 4, 2020
    Assignee: Bigfoot Biomedical, Inc.
    Inventor: Mark C. Estes
  • Patent number: 10531785
    Abstract: Systems, devices, and methods for fluid management in an endoscopic procedure are disclosed. In one embodiment, a fluid management device may comprise a pair of electrodes and a controller connected to the pair of electrodes. In at least some embodiments, the controller may be configured to receive signals from the pair of electrodes and determine whether a fluid in a fluid reservoir is an ionic fluid or a non-ionic fluid based on signals received from the pair of electrodes. In at least some additional embodiments, the controller may be further configured to automatically set a fluid deficit alarm threshold based on the determination of whether the fluid in the fluid reservoir is an ionic fluid or a non-ionic fluid.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: January 14, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Aaron Germain, Michael D. Walker, Jacob Roland, Jan Echeverry
  • Patent number: 10507283
    Abstract: A pump system for pain management may receive input related to a patient's real-time pain to provide automatic adjustments of pain medication bolus delivery based on deduced patient pain. The pump may also collect pain management information during the delivery of pain medication to provide data for improved pain management protocols.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: December 17, 2019
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Mei Zhang
  • Patent number: 10499895
    Abstract: An introducer sheath system including an outer layer, an inner layer, and a dilator is disclosed. The outer layer is circumferentially extending between a first longitudinal edge and a second longitudinal edge. An expandable gap is defined between the first and second longitudinal edges. The inner layer is disposed within the outer layer. The inner layer is configured to be continuously circumferentially expandable. The inner layer includes a non-extended state having a circumferential portion extending circumferentially inside the outer layer and a fold portion extending into an interior cavity of the inner layer. The inner layer includes an extended state wherein the fold portion extends at least partially circumferentially between the first and second longitudinal edges. The dilator is extendable longitudinally within the inner layer. The dilator includes a recess configured to accommodate the fold portion of the inner layer.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: December 10, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventor: Marc Anderson
  • Patent number: 10485460
    Abstract: A sweat sensing device includes at least one sweat generation unit capable of initiating sudomotor axon reflex (SAR) sweating in an indirect stimulation region and at least one analysis unit capable of sensing a physiological parameter of sweat, collecting a sweat sample, or a combination thereof. The at least one analysis unit is located above the indirect stimulation region when the sweat sensing device is placed on skin.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: November 26, 2019
    Assignee: University Of Cincinnati
    Inventors: Zachary Cole Sonner, Jason C. Heikenfeld
  • Patent number: 10449336
    Abstract: A device for occluding a perforation in a blood vessel includes an expandable member. The expandable member includes a central expandable balloon disposed between a proximal and a distal balloon, wherein the proximal and distal balloons each contain first and second compositions, respectively. The proximal, central and distal balloons have respective stiffnesses, and the central balloon has a third stiffness that is less than the first and second stiffnesses. Upon expansion, the central balloon causes the proximal balloon and the distal balloon to substantially simultaneously release the first and second compositions, thereby allowing the first composition and the second composition to combine in-situ and form, therein, a biocompatible foam to occlude a perforation within the vasculature.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: October 22, 2019
    Assignee: THE SPECTRANETICS CORPORATION
    Inventors: Grant Foy, Jay Harper
  • Patent number: 10434260
    Abstract: A drug delivery device comprising: a housing; a plurality of sensors; and a cylindrical member supported within the housing, an outer surface of said cylindrical member being provided with a helical track, the helical track comprising track segments of a first type and track segments of a second type, the first and second types of track segments being respectively capable of inducing first and second responses in the sensors; wherein: the helical track has a width; the helical track includes across the width of the helical track at least one track segment of the first type and at least one track segment of the second type at plural positions along a length of the helical track; the device is configured such that during a first phase of a drug delivery operation the helical track is moved axially, without rotation, relative to the plurality of sensors between a first position and a second position, and during a second phase of the drug delivery operation the track is moved helically relative to the plurality o
    Type: Grant
    Filed: January 13, 2014
    Date of Patent: October 8, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Samuel Keir Steel, Paul Richard Draper, Anthony Paul Morris, Stephen Gilmore
  • Patent number: 10420623
    Abstract: Various exemplary embodiments relate to a method of using an emergency medicament device. The method includes reading an ID tag from the medicament device using a mobile device; automatically requesting instructions for using the medicament device based on the ID tag; and displaying a video to a user of the mobile device, the video providing instructions for using the medicament device in accordance with approved labeling of the medicament device. Various exemplary embodiments relate to an electronic medicament device including: a reservoir configured to store an amount of medication for treating anaphylaxis; an administration component for administering the medication to a patient; a processor communicatively connected to a memory storing medicament device information; and an identification tag configured to be read by another device, the identification tag providing the medicament device information including identification of instructions for using the medicament device.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: September 24, 2019
    Assignee: Mylan Inc.
    Inventors: Kevin Ostrander, John W. Denny
  • Patent number: 10413240
    Abstract: An electronic device includes a balloon configured to contact a surface of a human conduit and one or more a biometric sensors operatively coupled to or on or in or within the balloon for detecting a biometric signal. The electronic device in some examples is a biometric sensor or measuring device. In other examples, the electronic device is an integrated device such as an earpiece having biometric sensors. In yet other examples, the electronic device can be operatively coupled to other device and other biometric sensors. Other embodiments are disclosed.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: September 17, 2019
    Assignee: Staton Techiya, LLC
    Inventor: Steven Wayne Goldstein
  • Patent number: 10405867
    Abstract: A device and methods for treating an aneurysm includes a catheter capable of insertion into a body to be positioned adjacent the aneurysm, the catheter including a distal end and an operator end opposite the distal end. The catheter forms a circular pathway extending between the distal end and the operator end. A partitioner extends through the pathway of the catheter, the partitioner being rotatable within the catheter and including one or more lumens that provide an orifice from a first end of the partitioner to a second end of the partitioner. The device further includes a first coil extending through the partitioner from the first end to the second end in a first lumen and a second coil extending through the partitioner from the first end to the second end in a second lumen. The first and second lumens may be fully circumscribed by the partitioner and have first and second diameters, respectively.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: September 10, 2019
    Assignee: Rush University Medical Center
    Inventor: Andrew K. Johnson
  • Patent number: 10406274
    Abstract: An accessing assembly for hemodialysis administration, having an intravascular tube assembly, a conduit assembly, first and second catheter sleeve assemblies, and first and second catheter assemblies. The intravascular tube assembly has an intravascular tube, a subcutaneous cuff, a tube end and a ring with a hole. The conduit assembly has first and second conduits having respective conduit threading. The first and second catheter sleeve assemblies have collapsible sidewalls, ends, and joining ends respectively. The collapsible sidewalls define cavities respectively, and couplers are defined within the cavities. The first and second catheter assemblies have catheter sidewalls, inlet/outlet ends, internal ends, and fasteners respectively. The catheter sidewalls have a plurality of holes. The intravascular tube is implanted within a vascular structure. The catheter sidewalls are positioned inside to respective collapsible sidewalls.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 10, 2019
    Inventor: Jose Ramirez
  • Patent number: 10405905
    Abstract: A bone graft delivery system can include an elongate tube, a handle having a trigger, and a tip. The trigger is actuated to deliver bone graft material through the tube. The tip has one or more openings to deliver the bone graft material to a desired location and includes a surface suitable to act as a rasp for decorticating bone. A method for delivering bone graft material to a desired surgical location includes providing a bone graft delivery device, positioning the device adjacent the surgical location, decorticating bone, and delivering bone graft material to the surgical location.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: September 10, 2019
    Assignee: SurGenTec, LLC
    Inventors: Travis Greenhalgh, Ryan Lewis
  • Patent number: 10390702
    Abstract: Devices for the local delivery of microdose amounts of one or more active agents, alone or in combination, in one or more dosages, to selected tissue of a patient are described. The devices generally include multiple microwells arranged on or within a support structure. The microwells contain one or more active agents, alone or in combination, in one or more dosages and/or release pharmacokinetics. In an exemplary embodiment, the device has a cylindrical shape, having symmetrical wells on the outside of the device, each well containing one or more drugs, at one or more concentrations, sized to permit placement using a catheter, cannula, or stylet. Optionally, the device has a guidewire, and fiber optics, sensors and/or interactive features such as remote accessibility (such as WiFi) to provide for in situ retrieval of information and modification of device release properties. In the most preferred embodiment, the fiber optics and/or sensors are individually accessible to discrete wells.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: August 27, 2019
    Assignee: Kibur Medical, Inc.
    Inventors: Robert I. Tepper, Jason Fuller, Oliver Jonas, John Santini
  • Patent number: 10376603
    Abstract: Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage oligomeric matrix protein and repeats of elastic like peptides. The coiled-coil domain allows delivery of molecules, the elastin-like peptide domain provides thermo-responsive functionality, and a plurality of leucine residues, which can be fluorinated, provide imaging functionality.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: August 13, 2019
    Assignee: New York University
    Inventors: Jin Kim Montclare, Joseph A. Frezzo, Cynthia Xu, Youssef Zaim Wadghiri
  • Patent number: 10363058
    Abstract: A surgical instrument for use during a surgical procedure includes an instrument body, an ultrasonic transducer assembly extending along a longitudinal axis, a power cord, and a transducer slip joint. The ultrasonic transducer assembly is rotatably mounted within the instrument body about the longitudinal axis and defines a first outer profile. The power cord projects from the instrument body to provide electrical power to the ultrasonic transducer assembly for operating an acoustic waveguide. The transducer slip joint is positioned between the power cord and the ultrasonic transducer assembly and electrically and mechanically connects the power cord to the ultrasonic transducer assembly. The ultrasonic transducer assembly selectively rotates relative to the power cord for inhibiting the power cord from winding upon rotation of the ultrasonic transducer assembly. The transducer slip joint also defines a second outer profile that fits within the first outer profile of the ultrasonic transducer assembly.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 30, 2019
    Assignees: Ethicon LLC, SAMTEC, Inc.
    Inventors: Eric Roberson, James E. Borgelt, Douglas E. McCartin
  • Patent number: 10327780
    Abstract: A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: June 25, 2019
    Assignee: SentreHEART, Inc.
    Inventors: John R. Liddicoat, William E. Cohn, Roger Laham
  • Patent number: 10322253
    Abstract: A cleaning device, system and method for use with an ETT or tracheostomy ventilation tube 60, a ventilator machine 900, a source(s) 602 of fluid (for example, pressurized or unpressurized) and a source(s) of suctioning 603 is disclosed. In some embodiments, the cleaning device is useful for cleaning an inner surface of the ventilation tube 60 and/or for preventing or hindering the accumulation of biofilm thereon. In some embodiments, it is possible to clean biofilm or any other material on the inner surface 201 by delivering fluid into an interior of the ventilation tube, wiping the tube interior with a width-expanded wiping element (e.g. an inflated balloon) by longitudinal motion of the wiping element, and suctioning material out of the ventilation tube ventilation tube.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: June 18, 2019
    Assignee: TELEFLEX LIFE SCIENCES UNLIMITED COMPANY
    Inventors: Elad Einav, Oron Zachar
  • Patent number: 10314568
    Abstract: A retractor features at least two retractor arms whose proximal end portions are fixed or integrally formed on opposite ends of a crossbar for adjusting the distance between the retractor arms, and a drive unit whose case is mounted on the crossbar and whose gearing is in operative connection with a length adjustment mechanism to be operated by a separate actuation element which can be brought into engagement with a gearing input element movably inserted in the case. The gearing input element is accessible on at least one outer side of the casing. The gearing input element is designed such that it is substantially flush with the case's outer side or is recessed into the case interior. It has its exposed side provided with recesses, at least one of which has an undercut which enters a manually detachable latching engagement with a force transmission protrusion of the actuation element.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: June 11, 2019
    Assignee: Aesculap AG
    Inventor: Robert Vogtherr
  • Patent number: 10319895
    Abstract: Among other things, one or more systems and/or techniques for harvesting thermal energy for utilization by a dispensing system are provided herein. The dispensing system may comprise one or more thermal scavenging devices configured to collect thermal energy from a user. For example, a first thermal scavenging device, coupled to a top housing portion of the dispensing system, may collect thermal energy from a palm of a user hand; a second thermal scavenging device, coupled to a bottom housing portion of the dispensing system, may collect thermal energy from a top portion of the user hand; and/or other thermal scavenging devices may be operatively coupled to the dispensing system. In this way, the collected thermal energy is transformed into electrical energy for powering the dispensing system (e.g., powering a current dispense event, stored for a subsequent dispense event, validation of a refill container, detection of a user, etc.).
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: June 11, 2019
    Assignee: GOJO Industries, Inc.
    Inventors: Jackson William Wegelin, Demetrius Henry, Nick Ermanno Ciavarella
  • Patent number: 10307613
    Abstract: An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a second portion at the distal end and at least one lumen associated with at least one of the first structural arrangement and/or the second structural arrangement. The first structural arrangement and/or the second structural arrangement can be configured to position the at least one lumen at a particular position with respect to the tissue. A tip is configured to aid in the insertion of the apparatus into the tissue(s).
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: June 4, 2019
    Assignees: MEMORIAL SLOAN-KETTERING CANCER CENTER, GC MEDTECH LLC
    Inventors: Gary A. Lamoureux, Gil'Ad N. Cohen, Karyn Goodman
  • Patent number: 10300247
    Abstract: An apparatus includes a catheter, an introducer, and an actuator. A distal end portion of the introducer is configured to be coupled to a peripheral intravenous line. The introducer defines an inner volume having a first portion that defines an axis parallel to and offset from an axis defined by a second portion. A first portion of the actuator is movably disposed in the first portion of the inner volume. A second portion of the actuator is movably disposed in the second portion of the inner volume and coupled to the catheter movably disposed in the second portion of the inner volume. The actuator moves the catheter between a first position, in which the catheter is disposed within the introducer, and a second position, in which at least a portion of the catheter is disposed within the peripheral intravenous line.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: May 28, 2019
    Assignee: VELANO VASCULAR, INC.
    Inventors: Pitamber Devgon, Kevin J. Ehrenreich, Richard Thomas Briganti
  • Patent number: 10293113
    Abstract: The present disclosure relates to a drive mechanism for an injection device for setting and dispensing of a dose of a medicament, the drive mechanism comprising: an inner body fixable inside a housing of the injection device, the inner body comprising an elongated shaft extending in an axial direction (z) and having an outer thread, a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, and a dose member axially displaceable between a dose setting position (S) and a dose dispensing position (D) relative to the display member, wherein the display member comprises at least one blocking member movable in axial direction (z) between a blocking position (B) and a release position (R) and engageable with a blocking structure on the outer circumference of the inner body, wherein when in blocking position (B) the blocking member axially engages with the dose member and with the blocking structure to block an axial displacement of the dose member from the dose settin
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Robert Veasey, John David Cross
  • Patent number: 10292711
    Abstract: A heart treatment device includes an annuloplasty ring for restoring function to a mitral valve, an occluder configured and arranged for implantation within a left atrial appendage and a connector interconnecting the annuloplasty ring and the occluder.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: May 21, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Richard J. Olson, Tracee Eidenschink
  • Patent number: 10272179
    Abstract: The present invention relates to a perforated semi-permeable device comprising, human pancreatic endocrine cells or human PDX1-positive pancreatic endoderm cells contained within a semi-permeable membrane comprising a synthetic material, wherein the synthetic material is polysulfone (PSF), nano-fiber mats, polyimide, tetrafluoroethylene/polytetrafluoroethylene (PTFE), expanded polytetrafluoroethylene (ePTFE), polyacrylonitrile, polyethersulfone, acrylic resin, cellulose acetate, cellulose nitrate, polyamide, or hydroxylpropyl methyl cellulose (HPMC), a cell encapsulation chamber, and at least one seal that is within the cell encapsulation chamber.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: April 30, 2019
    Assignee: ViaCyte, Inc.
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Emmanuel Edward Baetge
  • Patent number: 10258780
    Abstract: The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: April 16, 2019
    Assignee: Histologics, LLC
    Inventors: Neal Marc Lonky, Martin L Lonky
  • Patent number: 10253255
    Abstract: Size-tunable phosphorescent particles may be formed through self-assembly of biocompatible linear polymers, such as chitosan and other linear polymers, that bear positive surface charges, through polyelectrolytic complexation to a polyanionic metal phosphor, such as polyanionic gold(I) phosphor (AuP). The phosphorescent hydrogel nanoparticles and thin films thereof are useful for imaging, sensing of biological molecules, detection of hypoxia, and light-emitting devices. The phosphorescent hydrogel particles can be formed from a variety of linear polymers by physical cross-linking using polyelectrolytic light-emitting species, without the need for the phosphorescent complex to be entrapped in an existing microsphere or nanosphere polymer particle.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: April 9, 2019
    Assignee: UNIVERSITY OF NORTH TEXAS
    Inventors: Mohammad A. Omary, Sreekar Marpu
  • Patent number: 10206595
    Abstract: An intrauterine balloon apparatus to augment uterine birthing forces and assist fetal descent during parturition is provided. The body of the balloon apparatus begins packaged in a compressed state minimizing volume, enabling delivery through the birth canal. The apparatus is advanced to a proximal uterine location and deployed for operation by introducing a pressurized agent through its conduit, causing the body to expand and apply directional forces towards the infant and birth canal. The balloon body is shaped to apply pressures dispersed towards the infant and the bidirectional conduit enables fluid conduction as the infant descends. After the infant has successfully descended and been delivered through the birth canal, pressure within the balloon body is relieved through the conduit thereby collapsing the volume of the balloon body and enabling refraction through the birth canal.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: February 19, 2019
    Assignee: 3VO Medical, Inc.
    Inventors: Ed Chinchoy, Jay Snell, James Kelley
  • Patent number: 10188837
    Abstract: The disclosed device, systems and methods relate to a novel catheter, system and methods. The various catheter implementations are for use in cardiopulmonary resuscitation and other medical or surgical conditions that require emergency restoration of cerebral and cardiac blood supply. The catheter or catheters have one or more lumens and balloons. Two catheters connected to a control unit can be disposed within the body to occlude and perfuse a region of the circulatory system.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: January 29, 2019
    Assignee: Regents of the University of Minnesota
    Inventor: Ahmed Selim
  • Patent number: 10188270
    Abstract: A stent delivery system includes a guide catheter, a tubular stent into which the guide catheter can be inserted, and a tubular pusher catheter into which the guide catheter can be inserted and disposed nearer to a proximal end side than the stent. The pusher catheter includes a diameter expansion-suppressing part provided at a distal end part and having the same inner diameter as the stent and an intermediate part provided at a proximal end side of the diameter expansion-suppressing part and having a bending stiffness less than that of the diameter expansion-suppressing part. When the stent is pushed toward a distal end side by pushing the intermediate part of the pusher catheter toward the distal end side and bringing a distal end part of the diameter expansion-suppressing part into contact with a proximal end part of the stent, an inner diameter of the pusher catheter is prevented from expanding.
    Type: Grant
    Filed: September 17, 2016
    Date of Patent: January 29, 2019
    Assignee: OLYMPUS CORPORATION
    Inventors: Hiromichi Miyano, Toshihiro Yamagata
  • Patent number: 10159818
    Abstract: A safety needle system operable with a medical device includes: a housing with a needle mount having a needle; and a sheath telescopically engaged with the housing and surrounding the needle such that the sheath operates in a retracted position, in which the sheath exposes the needle, and an extended position, in which the sheath surrounds the needle. The sheath is coupleable to the medical device such that removal of the needle from the medical device draws the sheath over the needle, transitioning the sheath from the retracted position to the extended position. In one embodiment, the system includes a slider engaged with the sheath and/or housing and including a restraint that engages and disengages the sheath to respectively reinforce and weaken the coupling of the sheath and medical device. In another embodiment, the sheath includes a longitudinal track that slidingly engages a setting of the housing between sheath positions.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: December 25, 2018
    Assignee: Tangent Medical Technologies, Inc.
    Inventors: Nathan Farrell, Adrienne Rose Harris, Steven B. White, Ronald Dean Duis, Henry J. H. Brown
  • Patent number: 10159817
    Abstract: The present disclosure is directed to an over-the-needle (OTN) catheter assembly having a sleeve configured thereon. The catheter includes a body having an outer diameter. The body also includes a proximal end and a distal end and defines a lumen extending from the proximal end to the distal end. A needle is configured within the lumen of the catheter and extends from the proximal end to the distal end. The sleeve is configured around a portion of the outer diameter of the catheter that passes through an insertion site of the catheter. Further, the sleeve includes a length extending from a first end to a second end and is configured to prevent the catheter from collapsing along the length of the sleeve. In addition, the sleeve is configured to prevent leakage from the insertion site of the catheter.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: December 25, 2018
    Assignee: Avent, Inc.
    Inventor: Steve Saeed Khalaj
  • Patent number: 10143478
    Abstract: The present invention relates in general to anchoring systems for occluder devices, and more specifically, to an anchoring system and method for implanting an occluder device within a left atrial appendage (“LAA”) of the heart. The anchoring system is configured so that an anchor penetrates the inner endocardium layer, middle myocardium layer, and outer epicardium layer of an LAA wall. The purpose of the present invention is to provide an occluder device anchor that has a low risk of embolization and/or causing injury to neighboring valve structures. An additional purpose of the present invention is to provide an anchoring system and method for implanting an occluder device within the LAA that allows for the occluder device to be retrievable after initial placement, reusable, and repositionable for an optimal final placement within the LAA.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: December 4, 2018
    Inventor: Thomas J. Forbes