Liquid Therapeutic Material Administered With Solid Or Second Liquid Patents (Class 604/518)
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Publication number: 20110004143Abstract: This disclosure relates to drug delivery devices and related systems and methods. In certain aspects, a drug delivery device includes a pump extending from a surface of the drug delivery device and a door that includes a spring-loaded member exposed along its inner surface. The fluid line can be compressed between the spring-loaded member and the pump in a manner such that the fluid line is occluded in at least one location.Type: ApplicationFiled: June 30, 2010Publication date: January 6, 2011Inventors: Michael James Beiriger, Ryan Kaintz
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Publication number: 20100318063Abstract: A syringe system for dispensing or injecting one or more fluids is provided. The syringe system includes a hollow body that retains cartridge(s) and/or syringe(s) each containing a fluid, such as an injectable fluid e.g., a catalyst in one cartridge and a polymer in the other. Upon use for dispensing two fluids, the syringe system mixes the two fluids immediately prior to or concurrently with the dispensing or injecting of the fluids. The syringe system can also be configured to independently dispense a single fluid or immediately dispense multiple fluids sequentially.Type: ApplicationFiled: June 10, 2010Publication date: December 16, 2010Applicant: CLEO COSMETIC AND PHARMACEUTICALS CO., LLCInventor: David B. SOLL
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Publication number: 20100318062Abstract: A conveyor apparatus and a method for supplying a medicine-solution mixture from a plurality of medicine-active ingredient solutions and additional solution constituents in a body by means of a plurality of feed devices is disclosed. The medicine-active ingredient solutions have different medicine-active ingredient parameters and constituents; the solution constituents have different parameters and constituents. The constituents of at least two medicine-active ingredient solutions and solution constituents are saved in at least one storage device; and are selected by means of one selection device for selection of at least one specific parameter and/or constituent of each medicine-active ingredient solution and/or the solution constituents. By means of a calculating device, at least one additional parameter from all selected parameters is calculated for the control and operation of at least one additional feed device for supplying at least one additional medicine-solution mixture to the body.Type: ApplicationFiled: October 1, 2008Publication date: December 16, 2010Inventors: Hans-Martin Lauer, Matthias Wufka, Sebastian Hörnig, Doris Röthlein
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Publication number: 20100305548Abstract: A body portion of the apparatus comprises an interior cavity and a plurality of fluid lumens extending from the cavity to a periphery of the body portion. The apparatus further comprises a first fluid port in fluid communication with a first one of the fluid lumens. The first fluid port is configured to receive a syringe for injecting a liquid diluent and withdrawing a reconstituted liquid medicament. The apparatus further comprises a second fluid port in fluid communication with a second one of the fluid lumens. The second fluid port is configured to receive a medicament vial. The apparatus further comprises a third fluid port at an end of a third one of the fluid lumens for expelling the reconstituted liquid medicament. The apparatus further comprises a stopcock received within the body portion interior cavity and configured to regulate fluid communication between the fluid lumens.Type: ApplicationFiled: May 26, 2009Publication date: December 2, 2010Inventor: Timothy Y. Kraushaar
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Publication number: 20100298811Abstract: A steroid delivery system including a mixing syringe having a first chamber and a second chamber and at least one hypodermic needle is provided. The first chamber of the mixing syringe contains a pre-measured volume of a local anesthetic and the second chamber contains a pre-measured volume of a corticosteroid. An improved mixing syringe and a method for treating pain using the steroid delivery system of the present invention is also provided herein. The improved syringe achieves mixing without the introduction or elimination of air and without puncturing or rupturing of a membrane, diaphragm or other material. The kit concept improves the speed of the procedure, sterility, accuracy of dosing, and immediate availability of disparate items to implement the procedure in a variety of medical practice settings.Type: ApplicationFiled: May 22, 2009Publication date: November 25, 2010Inventor: Michael P. Connair
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Publication number: 20100292672Abstract: A syringe includes a cartridge and a second chamber. The cartridge includes a first chamber, a first end having a conduit in liquid communication with the first chamber, a liquid disposed within the first chamber, a second end moveable within the first chamber, and a locking mechanism. The conduit is adapted and configured to rely on a property of the liquid to prevent movement of the liquid out of the first chamber. The locking mechanism is adapted to prevent movement of the second end within the first chamber while in the locked configuration. The cartridge is moveable within the second chamber.Type: ApplicationFiled: July 9, 2010Publication date: November 18, 2010Inventor: Martin N. Lee
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Patent number: 7833216Abstract: A system for dispensing an adhesive comprises a first dispenser, a second dispenser, and a conduit. The first dispenser contains an adhesive. The second dispenser comprises a fluid. The first dispenser and second dispenser are each in fluid communication with the conduit. The conduit has an opening. One or both of the first dispenser or the second dispenser is operable to dispense adhesive or fluid through the opening of the conduit. The system may be used to apply adhesive to the tissue of a patient in a precise and controlled manner.Type: GrantFiled: November 8, 2006Date of Patent: November 16, 2010Assignee: Ethicon Endo-Surgery, Inc.Inventors: James Walden Voegele, Mark S. Ortiz, Christopher W. Widenhouse, Fredrick E. Shelton, IV
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Publication number: 20100268193Abstract: The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle.Type: ApplicationFiled: June 4, 2010Publication date: October 21, 2010Inventors: James M. Verespej, Philip Dowds
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Publication number: 20100262125Abstract: The invention relates to a disposable injector with a housing, with a cylinder/piston unit which is arranged thereon and has a manually movable piston, and with a detachable container adapter mounted upstream of this cylinder/piston unit, wherein the container adapter supports a container that is closed by an openable stopper. The piston of the cylinder/piston unit is movable via a pump rod. The container adapter engages at the front end around the cylinder of the piston/cylinder unit. The container adapter has an intermediate floor which supports a dual adapter having at least one through-channel. The container, which bears tightly with its stopper on the dual adapter, sits longitudinally displaceably in the rear of the container adapter. The container is opened by displacing it towards the intermediate floor and pushing the stopper into the container.Type: ApplicationFiled: May 24, 2010Publication date: October 14, 2010Inventor: Rudolf Matusch
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Publication number: 20100217231Abstract: The device for administering an at least two-component substance comprises a concentric lumen arrangement including (i) an inner cannula having a lumen with an inlet opening at a first end and a tip with an outlet opening at a second end opposite its first end, and (ii) an outer sheath having opposite first and second ends facing the respective first and second ends of the inner cannula, and surrounding the inner cannula along an axial length between the first and second ends of the inner cannula, wherein the outer sheath at its second end is sealingly and fixedly connected to the inner cannula and defining an outer lumen around the inner cannula, and wherein the inner cannula is provided with at least one opening for providing fluid communication between the outer lumen around the inner cannula and the lumen of the inner cannula.Type: ApplicationFiled: February 18, 2010Publication date: August 26, 2010Inventors: Erez Ilan, Moti Meron, Kfir Regev, Liliana Bar, Israel Nur
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Publication number: 20100204679Abstract: A mixing and injection apparatus including a needle and a needle base, a syringe attachment element and a mixing chamber engagement assembly including a needle chamber surrounding the needle and a first liquid conduit portion, sealed from the needle chamber and a mixing chamber engagement portion including a second liquid conduit portion communicating with the first liquid conduit portion and configured for communication with a mixing chamber, the syringe attachment element and the needle base being configured to permit liquid communication between an interior of the syringe and the first liquid conduit portion when the syringe attachment element and the needle base are in the first relative engagement orientation and to permit liquid communication between an interior of the syringe and the needle when the syringe attachment element and the needle base are in the second relative engagement orientation, axially separated from the first relative orientation along the injection axis.Type: ApplicationFiled: July 15, 2008Publication date: August 12, 2010Applicant: MEDIMOP MEDICAL PROJECTS LTD.Inventor: Igor Denenburg
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Publication number: 20100174162Abstract: An injection device for use with tissue of a mammalian body comprising a first tubular member and a second tubular member slidably disposed in the first tubular member. The first and second tubular members have respective proximal and distal extremities. The distal extremity of the second tubular member is provided with a needle that is extendable from the distal extremity of the first tubular member. The proximal extremity of the second tubular member is lockable relative to the proximal extremity of the first tubular member. The second tubular member has a column strength when locked within the first tubular member for limiting retraction of the second tubular member relative to the first tubular member during puncture of the tissue by the needle.Type: ApplicationFiled: January 5, 2010Publication date: July 8, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Edward J. Gough, Alan Stein
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Publication number: 20100130961Abstract: A method of reconstituting and administering an injectable fluid distributed to practitioners in dry-form includes receiving a drug or medicine in dry form, selecting a reconstitution concentration for the drug or medicine, reconstituting a desired number of units of the drug or medicine by adding diluent to the dry-form drug or medicine, selecting a syringe having units marked according to the selected reconstitution concentration, drawing up a desired number of drug or medicine units using the selected syringe, and administering a desired number of units according to the unit markings on the selected syringe. Such a syringe includes a barrel, a plunger assembly that has a plunger handle and a piston, a needle, and a needle cap. The syringe includes a visual indicia, representing a first drug concentration contained in the barrel, that is distinguishable from a corresponding visual indicia, on a second syringe, representing a second drug concentration.Type: ApplicationFiled: November 25, 2009Publication date: May 27, 2010Applicant: GUARDIAN DYNAMICS, LLCInventor: Peter L. TUCKER
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Publication number: 20100121310Abstract: A multiple component cartridge includes a barrel defining a chamber and a longitudinal axis. A first plunger is disposed within the chamber and in sealing engagement with the barrel. The first plunger includes at least one member and is movable relative to the barrel such that the at least one member is configured for movement relative to the first plunger to facilitate passage of at least a first component through the first plunger. A second plunger is disposed within the chamber and in sealing engagement with the barrel. The second plunger includes at least one member and is movable relative to the barrel such that the at least one member of the second plunger is configured for movement relative to the second plunger to facilitate passage of at least a second component through the second plunger.Type: ApplicationFiled: November 10, 2008Publication date: May 13, 2010Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Thomas A. SIMONTON, Sean M. HADDOCK, Lehmann K. LI
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Publication number: 20100114067Abstract: Mixing systems for storing and mixing multiple components of various medical compositions are provided. Generally, the instant mixing systems comprise a barrel, a plunger slidably disposed inside a barrel, and a pushing rod slidably disposed inside the plunger. The instant mixing system may further comprise multiple chambers for storing individual components or mixtures of components, with at least one chamber disposed in the barrel and at least one chamber disposed inside the plunger.Type: ApplicationFiled: October 31, 2008Publication date: May 6, 2010Applicant: Warsaw Orthopedic, Inc.Inventors: Hai H. Trieu, Sean M. Haddock
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Publication number: 20100106138Abstract: A system for expressing two materials onto a selected site is disclosed. The system can include a syringe that is operable to maintain two separated materials substantially separate until a selected time. The system can further include a tip portion operable to direct the two materials, either mixed or unmixed, to a selected site. The materials can include tissue sealants, growth factors, or other appropriate materials to be directed to a selected site.Type: ApplicationFiled: October 29, 2008Publication date: April 29, 2010Applicant: Biomet Biologics, LLCInventor: Jason Chavarria
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Publication number: 20100106139Abstract: A syringe-carpule assembly comprising first and second carpules, a housing holding the first and second carpules in an end-to-end relationship, an outer hollow plunger rod supported by and slidable relative to the housing, and an inner hollow rod having first and second openings and being slidably arranged inside the outer hollow plunger rod. The inner hollow rod is slidable between first and second positions. The inner hollow rod in the first position has the first opening disposed within the first carpule and the second opening disposed within the second carpule. This allows liquid solvent in the second carpule to flow into the first carpule, which comprises an evacuated chamber containing solid matter that dissolves in the presence of that solvent to form a mixture. The second carpule is then removed and the mixture in the first carpule is injected into the patient.Type: ApplicationFiled: October 28, 2009Publication date: April 29, 2010Inventor: Steven Schulhof
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Publication number: 20100087799Abstract: An administering device for administering an active substance from a multi-chamber container comprising a first chamber holding a solid active substance and a second chamber holding a dissolving liquid for the active substance, wherein the administering device comprises a mixing device for mixing the active substance with the dissolving liquid and a housing accommodating the mixing device, the container being moveable relative to the housing, and the administering device further comprising a first indicator for indicating a position of the container relative to the housing upon completion of a mixing step, and a second indicator for indicating a position of the container relative to the housing upon completion of a venting step.Type: ApplicationFiled: October 2, 2009Publication date: April 8, 2010Inventors: Sofia Galbraith, Ulrich Moser, Juerg Hirschel, Ian Thompson
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Publication number: 20100082013Abstract: A diluent/medication mixing syringe assembly is described which includes a cannula which extends through a syringe plunger assembly into a reservoir of the syringe assembly. The cannula facilitates injection of a diluent, medication or other fluid into the fluid reservoir of the syringe assembly immediately prior to use for mixing with a medication in the reservoir. In one embodiment, a mixing element is secured to a distal end of the cannula within the reservoir to improve mixing efficiency.Type: ApplicationFiled: September 23, 2009Publication date: April 1, 2010Applicant: Tyco Healthcare Group LPInventors: Richard Braga, Casey Chebator
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Publication number: 20100063474Abstract: The present invention relates to a mixing syringe device for delivering a medicament or medical composition to a site of interest. The mixing syringe device generally includes a multi-chambered open lumen and optionally a sectioned plunger. The open lumen has at least two longitudinally oriented chambers within the interior of the lumen, and the optional sectioned plunger has at least two longitudinally oriented extensions corresponding in configuration to the at least two longitudinally oriented chambers of the open lumen and configured to be reciprocatably disposed in the chambers of the open lumen. Each compartment of the lumen is configured to store a medicament component or medical composition component in its interior. In certain embodiments, each compartment is sealed at one end by a movable stopper mechanism and sealed at the other end by a sealing mechanism capable of temporarily or otherwise opening. Methods of use are also provided.Type: ApplicationFiled: September 8, 2009Publication date: March 11, 2010Applicant: Thomasevans, LLCInventor: Richard T. EVANS, JR.
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Patent number: 7669597Abstract: Dosage forms containing pharmaceutical compositions for use in devices to produce a spray or mist delivery of the compositions include dosage blister compartments and a dispensing blister compartment, wherein crushing of the compartments delivers the compositions in a desired spray pattern. Certain dosage forms include a plurality of dosage chambers each containing a component or a portion of a pharmaceutical composition, the contents of which are mixed or combined just prior to or during administration.Type: GrantFiled: May 15, 2008Date of Patent: March 2, 2010Assignee: Mystic Pharmaceuticals, Inc.Inventors: Timothy R. Sullivan, Jeffrey Nelson
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Publication number: 20090306623Abstract: A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated.Type: ApplicationFiled: August 10, 2009Publication date: December 10, 2009Applicant: ARTERIOCYTE MEDICAL SYSTEMS, INC.Inventors: Kevin D. McIntosh, Richard M. Albrecht
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Publication number: 20090287184Abstract: A two-chambered, sequentially injectable syringe is disclosed. The syringe has two concentric barrels, substantially cylindrical in shape. The outer barrel has an open end adapted for receiving an inner barrel/first piston. The inner barrel/first piston contains a flushing liquid. The syringe has a second piston slidably movable in the inner barrel and a latching mechanism that can alternate between a locked configuration and an unlocked configuration. In the locked configuration, the latching mechanism prevents the second piston from substantially all longitudinal movement relative to the inner barrel. In the unlocked configuration, the latching mechanism permits longitudinal motion of the second piston within the inner barrel.Type: ApplicationFiled: July 22, 2009Publication date: November 19, 2009Inventor: Martin Nicholas Lee
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Patent number: 7601128Abstract: An assembly for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The assembly comprises an acoustic wave generator and transducer for the generation and transmission of unfocused acoustic waves, a source of microbubble solution and solution injection members for percutaneously injecting the solution at a treatment area between 1 mm and 5 mm below the dermis. The assembly is useful for treatment of subcutaneous abnormalities including cellulite, lipomas and tumors.Type: GrantFiled: January 17, 2006Date of Patent: October 13, 2009Assignee: Cabochon Aesthetics, Inc.Inventors: Mark E. Deem, Hanson S. Gifford, III, Douglas Sutton
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Publication number: 20090234326Abstract: A sprayer is capable of inhibiting or preventing clogging occurring in a nozzle upon ejection of a liquid through the nozzle. A sprayer includes liquid supply for separately supplying a first liquid and a second liquid different in liquid composition, and a nozzle. The nozzle includes a first flow path and a second flow path along which passes the first liquid and the second liquid supplied from the liquid supply. In addition, the nozzle includes a third flow path along which passes a gas. A merge part is provided at which the first flow path and the second flow path merge at their respective halfway parts. A vent is provided at the merge part for allowing the gas which has passed through the third flow path to flow into the merge part.Type: ApplicationFiled: March 11, 2009Publication date: September 17, 2009Applicant: TERUMO KABUSHIKI KAISHAInventor: Koichi HAYAKAWA
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Publication number: 20090198217Abstract: Two convenience kits are disclosed. A first convenience kit provides a basic configuration for use in measuring, filling and dispensing medication and flush solutions to IV sets and patient catheters through needleless connectors while improving safety and efficacy by requiring fewer post-sterilization makes and breaks compared to conventional filling and dispensing methods. A second convenience kit which, being a companion to the first convenience kit, provides safety in access to a vial. Methods of use of both kits improve flush compliance by facilitating dispensing of flush solutions and decreases likelihood of infections by providing for flushing of connecting sites while reducing numbers of breaks required for associated medical procedures.Type: ApplicationFiled: January 6, 2009Publication date: August 6, 2009Inventors: Gale H. Thorne, JR., Gale H. Thorne
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Publication number: 20090149746Abstract: A method of forming a soft tissue biopsy cavity marker may include steps of providing a radio-opaque element and a bio-compatible and bio-degradable polymer such as alginate and delivering the provided radio-opaque element and the provided polymer to a biopsy site, such as a breast biopsy site. A gelling initiator that includes divalent cations such as NaCl2 may then be provided and delivered to the biopsy site, causing the previously delivered polymer to gel and to form a soft tissue biopsy marker in situ (within the biopsy site).Type: ApplicationFiled: November 19, 2008Publication date: June 11, 2009Applicant: RUBICOR MEDICAL, INC.Inventors: Ary CHERNOMORSKY, John Soo Hoo, James W. Vetter
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Publication number: 20090143765Abstract: A device for mixing and delivering a mixture of fluids to a target site includes a tube for containing the mixture. A compressible auger for mixing the fluids is movably disposed within the tube, one end of the auger being free at the distal end of the tube. A plunger is also movable within the tube in communication with the other end of the auger. When the plunger is moved axially within the tube the auger also moves axially and the auger is compressed to dispense the fluid. The mixing and delivery device can be used with an apparatus for the arthroscopic delivery of a tissue repair material to a repair site. The apparatus includes a first sheath and a second sheath removably attached to the first sheath for delivering the tissue repair material to the repair site.Type: ApplicationFiled: February 9, 2006Publication date: June 4, 2009Applicant: The Childrens Medical Center CorporationInventors: Alexander Slocum, Matthew R. Carvey, Alexey Salamini, Daniel G. Walker, Ying-Chih Wang, Martha M. Murray
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Publication number: 20090143766Abstract: A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network for a wide variety of tissue types. In particular, artificial or synthetic cartilage, vocal cord material, vitreous material, soft tissue material and mitral valve material are described. In an embodiment, the network is composed of tyramine-substituted and cross-linked hyaluronan molecules, wherein cross-linking is achieved via peroxidase-mediated dityramine-linkages that can be performed in vivo. The dityramine bonds provide a stable, coherent hyaluronan-based hydrogel with desired physical properties.Type: ApplicationFiled: January 29, 2009Publication date: June 4, 2009Applicant: The Cleveland Clinic FoundationInventors: Anthony Calabro, Lee Akst, Daniel Alam, James Chan, Aniq B. Darr, Kiyotaka Fukumachi, Richard A. Gross, David Haynes, Keiji Kamohara, Daniel P. Knott, Hilel Lewis, Alex Melamud, Anthony Miniaci, Marshall Strome
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Publication number: 20090118696Abstract: Methods for delivery of a compound within a tube.Type: ApplicationFiled: October 31, 2007Publication date: May 7, 2009Inventor: Eldon H. Nyhart, JR.
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Publication number: 20090093793Abstract: Apparatus is described for administering a substance to a subject. A vial contains the substance, an inner surface of the vial being shaped to define a protrusion therefrom. A stopper within the vial is slidably coupled to the vial. A first threaded element is (a) rotatable and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. The protrusion impedes rotation of the second threaded element with respect to the vial. The distal end of the second threaded element remains proximal to a distal end of the stopper during rotation of the first threaded element. The first threaded element, by rotating, linearly advances the stopper and the second threaded element toward a distal end of the vial. Other embodiments are also described.Type: ApplicationFiled: October 2, 2008Publication date: April 9, 2009Inventors: Yossi Gross, Oz Cabiri, John Paproski, Moshe Barkan
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Publication number: 20090093792Abstract: Apparatus is described for administering a substance to a subject. A vial contains the substance and a stopper is disposed within the vial and is slidably coupled to the vial. A first threaded element is (a) rotatable with respect to the vial and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. At least a distal end of the second threaded element is substantially non-rotatable with respect to the vial, and the distal end of the second threaded element defines a coupling portion that couples the second threaded element to the stopper. The first threaded element, by rotating, linearly advances the stopper and at least the distal end of the second threaded element toward a distal end of the vial. Other embodiments are also described.Type: ApplicationFiled: October 2, 2008Publication date: April 9, 2009Inventors: Yossi Gross, Oz Cabiri
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Publication number: 20090075231Abstract: A method and device delivers a medicament to a selected tissue for treatment of the tissue, plaque and biofilm included. In the device, a first reservoir member is used to connect to a fluid source. Further, a second reservoir member engages the first reservoir member to define a chamber for receiving the medicament. Structurally, the second reservoir member includes an outlet. Attached to the outlet is a tube that extends to a nozzle. When connected, the first reservoir member, second reservoir member, and tube define a passageway from the fluid source to the nozzle. During use, a flow rate for a fluid is established through the passageway to deliver the medicament from the passageway through the nozzle to the selected tissue.Type: ApplicationFiled: September 14, 2007Publication date: March 19, 2009Inventors: Russell C. Tontz, Robert S. White
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Publication number: 20090043282Abstract: This description relates to drug delivery devices (100), as well as related components, systems and methods.Type: ApplicationFiled: April 26, 2006Publication date: February 12, 2009Applicant: WYETHInventors: Martin Hughes, Darren Seymour, Colin Turner, Paul Harmer, Yannick Hourmand
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Publication number: 20090012497Abstract: A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.Type: ApplicationFiled: December 20, 2007Publication date: January 8, 2009Applicant: MEDRAD, INC.Inventors: Arthur E. Uber, III, David M. Griffiths, David M. Reilly, Alan D. Hirschman, Kevin P. Cowan, Mark Trocki
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Publication number: 20080287913Abstract: Systems and methods of co-injecting a solid object and an amount of fluid into a patient's tissue includes separably coupled syringe and needle portions. The syringe portion includes a barrel, a plunger, and a pushrod for disposing the solid object that is capable of independent movement with respect to the plunger. The needle portion includes a hollow needle configured to allow both the object and the fluid to pass out of the needle and into the patient's tissue. The needle portion may include a housing located behind the needle that is configured to hold the solid object. Once the needle portion and the syringe portion are coupled together, the device is operated in accordance with methods of the present invention to effectively co-inject the patient with the object and the amount of fluid.Type: ApplicationFiled: May 17, 2007Publication date: November 20, 2008Inventor: Lester M. Schwab
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Publication number: 20080262413Abstract: Oxygenated aqueous fluids are provided by passing aqueous hydrogen peroxide through a device containing a hydrogen peroxide decomposition catalyst. The oxygenated fluid is then used to elevate oxygen tension in a patient in need thereof.Type: ApplicationFiled: April 15, 2008Publication date: October 23, 2008Inventor: Daniel A. Ladizinsky
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Publication number: 20080234653Abstract: A freeze-dried material is stored in a first chamber of a container along with a reconstituting liquid for the freeze-dried material, which is stored in a second chamber of the container. A sealing wall within the container forms a barrier between the first chamber and the second chamber preventing contact between the freeze-dried material and the reconstituting liquid. At least one valve assembly in the sealing wall selectively opens a region of the sealing wall to establish fluid flow communication between the first and second chambers, allowing the freeze dried material to be reconstituted. The reconstituted freeze-dried material can be administered from the same container to a recipient.Type: ApplicationFiled: July 27, 2007Publication date: September 25, 2008Inventors: Simon J. McCarthy, William D. Block, John W. Morgan
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Publication number: 20080234654Abstract: A vessel receives a liquid material, which is freeze-dried in situ within the vessel. A gas permeable material carried by the vessel provides gas transport for sublimation during drying. After freeze drying, an oxygen-free inert gas is introduced into the vessel through the gas permeable material, to occupy the interior of the vessel with the freeze-dried material. The gas permeable material is covered, to trap the oxygen-free inert gas within the vessel with the freeze-dried material. The freeze-dried material is stored in the entrapped oxygen-free inert gas within the vessel for a storage period. The vessel receives a reconstituting liquid for mixing with the freeze-dried material, and conveys the reconstituted freeze-dried material from the vessel for administration to an individual.Type: ApplicationFiled: March 19, 2008Publication date: September 25, 2008Inventors: Simon J. McCarthy, William D. Block, John W. Morgan, Lisa A. Buckley, Lance D. Hopman, Clinton B. Pepper
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Publication number: 20080200862Abstract: The invention comprises a method to administer stem cells to a patient in need thereof. The method provides acoustically active material, stem cells, and an ultrasound energy emitting device. The method administers the acoustically active material to the patient, administers the stem cells to the patient, and administers ultrasound energy to the patient using the ultrasound emitting device.Type: ApplicationFiled: November 8, 2005Publication date: August 21, 2008Applicant: IMARX THERAPEUTICS, INC.Inventors: Evan C. Unger, Rachel LaBell, Terry O. Matsunaga, Reena Zutshi
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Publication number: 20080195082Abstract: The present invention relates to a syringe for storage, mixing and dispensing of multi-component paste materials, and more precisely to a syringe for two or more components of a paste material which are to be mixed together.Type: ApplicationFiled: June 3, 2005Publication date: August 14, 2008Inventors: Helmut Pauser, Michael Knee, Ingo W. Wagner
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Publication number: 20080161772Abstract: Devices and methods for injecting or otherwise delivering multiple-component therapies to human or animal subjects. Devices having injectors (e.g., syringes) attached to biaxial or coaxial injection cannula(s) are used to deliver multiple components of a particular therapy such that those components become combined shortly before or upon exiting the injection cannula(s). In some embodiments, the injector devices of the present invention may include a first set of finger grips at a first location and a second set of finger grips at a second location. Also, in some embodiments, the injector devices of the present invention may include depth slops for controlling the depth within tissue at which the therapeutic substance is delivered. Also, in some embodiments, the injector devices of the present invention may include refill manifolds with attached syringes or other reservoirs containing the component substances to facilitate refilling of the injectors.Type: ApplicationFiled: January 3, 2008Publication date: July 3, 2008Applicant: Medtronic Vascular, Inc.Inventors: Asha Nayak, Mario Maciel
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Publication number: 20080114334Abstract: A method for creating an identifying mark on tissue within a patient is disclosed. The method comprises the step of first positioning a surgical marker device within the patient's body. Next, the tissue is studied and identified, and one or more visible marks are drawn on the internal tissue. The visible the marks comprise a mix of a visible pigment and a polymer adhesive that is selected from the group consisting of a polymerizable monomer, a polymerizable 1,1,1,1-disubstituted ethylene monomer, and a cyanoacrylate. The visible marks are adhered to the tissue by polymerizing the polymer adhesive with tissue contact.Type: ApplicationFiled: November 10, 2006Publication date: May 15, 2008Inventor: James W. Voegele
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Publication number: 20080097389Abstract: A-type blood transfusion set having a blood limb, a saline limp and common limb and a one-way saline valve provided in the saline limb which only allows fluid within the saline limb to flow toward the Y connector. The blood limb and saline limb are color coded or marked with some type of identification so that, prior to coupling the blood limb to a source of blood or the saline limb to a source of saline, visual identification of the saline limb, having the one-way saline valve therein, can be readily achieved.Type: ApplicationFiled: July 10, 2006Publication date: April 24, 2008Inventor: Roland B. Wilson
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Patent number: 7351237Abstract: Devices and methods for testing a pulmonary vein to determine whether or not ablation would be effective in terminating atrial fibrillation. The devices and methods include a catheter having an expandable balloon attached to the distal end of the catheter. The balloon has pores on the distal end of the balloon for administering a fluid into the target pulmonary vein. The fluid inhibits the electrical impulses generated by the target pulmonary vein. Once the electrical impulses of the target pulmonary vein have been inhibited it can be determined whether or not the atrial fibrillation continues to occur. If the atrial fibrillation has been eliminated, then ablation or other therapy is appropriate. Thus, the devices and methods limit unnecessary treatment of a pulmonary vein.Type: GrantFiled: August 2, 2005Date of Patent: April 1, 2008Assignee: BioCardia, Inc.Inventor: Peter A. Altman
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Patent number: 7270654Abstract: A delivery catheter for delivering material(s) into the body of a mammal can include a first elongated member and a second elongated member. At least a portion of the second elongated member can be slidably disposed within a lumen of the first elongated member. The delivery catheter can mix two materials and then introduce the mixed materials into the body of a mammal.Type: GrantFiled: September 30, 2003Date of Patent: September 18, 2007Assignee: Boston Scientific Scimed, Inc.Inventors: John A. Griego, Marcia Buiser, Carla M. Wiese
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Patent number: 7081103Abstract: A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device capable of coupling the individual reservoirs of a dispensing instrument to multiple fluid containers. The apparatus includes a body, a collar extending from the body, a plurality of tubes in fluid communication with a plurality of inlet ports formed in the body, and a hood adapted to simultaneously receive a plurality of containers therein. The containers are positioned within the hood to allow the plurality of tubes to simultaneously and separately draw fluid from the fluid containers and transferring the material into the individual reservoirs of the dispensing instrument.Type: GrantFiled: November 4, 2002Date of Patent: July 25, 2006Assignee: Baxter International Inc.Inventors: Gordon Howard Epstein, Mitchell E. Levinson, Richard Spero
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Patent number: 6981967Abstract: A device and method for the infusion of medicinal fluid at a controlled flow rate to a wound site or the blood stream of a patient is disclosed. A pump delivers fluid under pressure from a fluid source through a continuous and substantially constant flow path and through a supplemental bolus dose flow path. A large volume bolus dose reservoir accumulates a large quantity of fluid from the bolus dose flow path and holds the fluid under pressure. A flow regulator controls the fill rate of the large volume bolus reservoir. The large volume supplemental bolus dose is released from the bolus reservoir upon patient activation of a valve. The release rate of the bolus dose is controlled by the decompression of an elastomeric sphere or spring chamber, by the pressure gradient at the valve and/or by optional flow control tubing.Type: GrantFiled: June 3, 2002Date of Patent: January 3, 2006Assignee: I-Flow CorporationInventors: Roger Dillard Massengale, Kenneth W. Rake, Eric Mabry
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Patent number: 6896670Abstract: An injection device for intramuscular or subcutaneous injection of solid or semi-solid medicaments is disclosed. The device includes main body member having a needle attached thereto. A protective sleeve covers the needle and retracts into the main body member when the device is pressed against the skin of a patient. A plunger with an attached rod maintains the medicament in the patient as the needle is withdrawn.Type: GrantFiled: September 26, 2002Date of Patent: May 24, 2005Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, S.A.S.Inventor: Roland Cherif Cheikh
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Patent number: 6821264Abstract: A gene delivery device for localizing and enhancing the efficacy of gene transfer that provides a contact surface for contacting with a tissue site. By applying a pharmaceutical composition comprising a nucleic acid to a contact surface and contacting the contact surface to a tissue site, a greater than 10-fold increase in transduction efficiency is achieved. In one embodiment of the invention, the device comprises a housing in communication with a contact surface having multiple contact elements, and the pharmaceutical composition is applied to the contact elements through a lumen in the device.Type: GrantFiled: November 27, 2000Date of Patent: November 23, 2004Inventors: Gautam Khurana, Stephen James Russell, Zvonimir S. Katusic