Abstract: The invention relates to the radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. In particular the invention relates to an endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. Furthermore the invention relates to an afterloading apparatus for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject using an endorectal probe device according to the invention. Moreover the invention relates to a method for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject, wherein the method implements the endorectal probe device according to the invention.

Abstract: A balloon catheter includes an outer shaft, an inner shaft, and an inflatable balloon. The inner shaft is inserted inside the outer shaft. A part of the inner shaft extends from a leading end of the outer shaft. The balloon includes a base end side joint portion joined to the outer shaft and a leading end side joint portion joined to the inner shaft. The inner shaft has an extension portion configured to in an axial line direction. The extension portion is provided further to a base end side than the leading end side joint portion.

Abstract: An intravascular catheter may include a distal end for insertion and a proximal end. The distal end for insertion may terminate with a tip. It may define at least two openings, of which one is the proximal-most in the distal end. The distal tip may include a first radiopaque marker that is discretely positioned at the proximal-most opening and radiographically distinguishes the proximal-most opening from the rest of the distal end. The distal tip may also include a second radiopaque marker that marks the tip.

Abstract: A multi lumen catheter assembly. The assembly provides an expandable, low profile, fixed length sheath and catheter, with fixed infusion ports. The assembly has an expandable outer sheath that expands upon pressure activation with a fluid and the sheath allows the fluid to exit from at least one predetermined fixed location from a distal end of the catheter assembly. The catheter assembly can be used in various medical device procedures, such as a TIPS (Transjugular Intrahepatic Portosystemic Shunt) procedure, or anywhere a low profile, multi lumen, infusion catheter system is desired.

Abstract: A catheter pump includes a catheter body having at least one lumen therethrough, and comprising a distal end and a proximal end. An expandable impeller assembly includes an expandable impeller and an expandable cannula coupled to the distal end of the catheter body and housing the expandable impeller, the expandable cannula comprising a substantially straight segment having a distal inlet and a proximal outlet, the substantially straight segment configured to straddle an aortic valve. The catheter body comprises a proximal vessel contact zone and a distal vessel contact zone that are each proximal to the substantially straight segment, the proximal vessel contact zone and distal vessel contact zone configured to provide a force against an aortic arch to stabilize the expandable impeller assembly across the aortic valve.

Abstract: The present invention concerns a device for the ventricular emergency support, comprising: a first flexible catheter (2), with a variable transversal section, provided with an extremal balloon (7) for the controlled occlusion of the ascending aorta (AA) of the treated patient; a first pump (12), associated to said first catheter (2) for the aspiration and contemporary input of equivalent blood quantifies into the blood circle of the treated patient; a second flexible catheter (32), with a fixed transversal section, provided with a couple of extremal balloons (34), spaced apart, for the controlled occlusion of the inferior vena cava (CA) and of the superior vena cava (CD) of the treated patient; a second pump (35), associated to said first and second catheter (2, 32) for inflating and deflating said extremal balloons (7, 34) of said first and second catheter (2, 32); an electronic control unit (36) for adjusting and controlling the operational parameters of said first and second pump (12, 35), and for the dete

Abstract: Systems and methods for performing aspiration thrombectomy. The aspiration catheter assembly can include a support catheter and an aspiration catheter extending through the support catheter. The catheter assembly can include a distal valve apparatus that can control a level of vacuum at a distal end of the catheter system. Irrigation can flow between the support catheter and the aspiration catheter to flush the catheter assembly.

Abstract: A medical device is provided that can be held and operated with a single hand to cause a catheter to be placed at a selected location in a patient's body. The user's other hand is free to perform other tasks, such as operating an ultrasound probe, for example. The medical device may also include a valve that can be operated with the same hand that holds the medical device to open a port to cause a fluid, such as a nerve block agent, for example, to be injected into the patient's body at the selected location.

Abstract: A multi lumen catheter assembly. The assembly provides an expandable, low profile, fixed length sheath and catheter, with fixed infusion ports. The assembly has an expandable outer sheath that expands upon pressure activation with a fluid and the sheath allows the fluid to exit from at least one predetermined fixed location from a distal end of the catheter assembly. The catheter assembly can be used in various medical device procedures, such as a TIPS (Transjugular Intrahepatic Portosystemic Shunt) procedure, or anywhere a low profile, multi lumen, infusion catheter system is desired.

Abstract: A medical braided tube assembly includes a braided tube including a hollow cylindrical inner resin layer, a braided wire including braided strands and being provided over a periphery of the inner resin layer, and an outer resin layer provided to cover peripheries of the inner resin layer and the braided wire, and a connector provided at an end portion of the braided tube. The connector includes a tube housing section for accommodating the end portion of the braided tube. The braided tube accommodated in the tube housing section are adhesively fixed by an adhesive. The adhesive is provided to seal an entire periphery of the braided wire at an end face of the braided tube.

Abstract: A catheter assembly for use in accessing a vasculature of a patient is disclosed. In one embodiment, the catheter assembly includes a catheter body that includes a flattened oval outer surface and defines first and second lumens. The catheter body defines a distal tip region that includes a venous lateral opening that is in fluid communication with the first lumen and includes a distal-facing portion. The distal tip region further includes an arterial lateral opening that is in fluid communication with the second lumen, includes a distal-facing portion, and is substantially un-staggered with respect to the venous lateral opening. A distal end opening is in fluid communication with a power injectable third lumen. In another embodiment, the first and second lumens each generally include a reniform cross-sectional shape. In yet another embodiment, a dual-lumen catheter includes first and second lumens that each define a modified ellipse cross-sectional shape.

Abstract: Rapidly insertable central catheters (“RICCs”) including catheter assemblies and methods thereof are disclosed. A RICC assembly can include a RICC, an introducer, and a coupling system configured to couple the RICC and the introducer together. A catheter tube of the RICC includes a side aperture in a distal-end portion of the catheter tube, which opens into an introducing lumen extending from the side aperture to a distal end of the RICC. The introducer includes a syringe and an introducer needle having a cannula. The coupling system includes a distal coupler slidably attached to the catheter tube proximal of the side aperture. The cannula extends through a longitudinal through hole of the distal coupler, through the side aperture of the catheter tube, along the introducing lumen of the catheter tube, and through the distal end of the RICC when the RICC assembly is in at least a ready-to-deploy state thereof.

Abstract: An implant delivery tube fitting (12) and an implant delivery system. The implant delivery tube fitting (12) is used for loading and delivering an implant, and the implant delivery tube fitting (12) comprises, sequentially from a proximal end to a distal end, an outer tube (122) and a capsule (121). The inner lumen of the capsule (121) is adapted to receive an implant, and the capsule (121) is provided at the distal end of the outer tube (122). The capsule (121) has a telescopic structure, and the outer tube (122) can drive the capsule (121) to make a telescopic movement so that the capsule (121) is lengthened or shortened.

Abstract: A uterine fibroid tissue removal device includes an inner tube disposed within an outer tube and configured to be translated and rotated relative to the outer tube, and a separately formed unitary distal tip member attached to a distal end of the inner tube, such that the distal tip member translates and rotates relative to the outer tube along with the inner tube, wherein a distal facing open cutting end of the distal tip member in fluid communication with an axial lumen of the distal tip member translates across a tissue resection window in a sidewall of the outer tube so as to sever tissue extending therethrough, the distal tip member axial lumen being in fluid communication with an axial lumen of the inner tube, wherein an outer diameter of the distal tip member is greater than an outer diameter of the inner tube.

Abstract: An apparatus including a therapeutic substance delivery device configured for attachment to a first tissue area internal of a recipient, the delivery device configured to enable movement of a therapeutic substance outlet of the delivery device proximate a second tissue area away from the first tissue area after attachment to the first tissue area to deliver the therapeutic substance from the outlet while implanted in the recipient.

Abstract: Catheters are described that have improved flow characteristics that may be particularly helpful when delivering embolic agents within a blood vessel. One catheter includes a fluid flow modifier that is configured to create laminar fluid flow out of a distal end of the catheter to help reduce turbulence and achieve predictable fluid movement. Another catheter includes scavenging ports that are configured to suction in embolic agents that have refluxed proximally back from a distal end of the catheter.

Abstract: The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.

Abstract: A catheter assembly includes: a catheter including a circumferential wall and a distal opening; an inner needle inserted through the catheter, the inner needle having a sharp needle tip at a distal end of the inner needle; and a deflection suppression mechanism that supports the inner needle via the catheter to suppress deflection of the inner needle, the deflection suppression mechanism including a contact support portion that is configured to support the catheter when the catheter is advanced with respect to the inner needle. The circumferential wall of the catheter includes one or more side holes. In an initial state before the catheter is advanced with respect to the inner needle, the contact support portion is located proximal of a distal-most one of the one or more side holes and a gap is formed between an outer surface of the catheter and an inner surface of the contact support portion.

Abstract: The invention concerns methods of treating blood, blood product, or physiologic fluid to provide at least one of (i) increasing shelf life of the blood, blood product or physiologic fluid, (ii) maintaining freshness of new blood, blood product or physiologic fluid, and (iii) removing undesirable molecules from the blood, blood product or physiologic fluid; said method comprising contacting said blood, blood product or physiologic fluid with a sorbent, said sorbent being primarily in a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of at least one of (1) zwitterionic moieties and (2) oligo(ethylene glycol) moieties attached to the surface of said cross-linked polymeric material.

Abstract: A catheter system for ablation of tissue around a blood vessel, e.g., the pulmonary artery, to reduce neural activity of nerves surrounding the blood vessel. The catheter system includes an elongate shaft having a proximal portion coupled to a handle, and a distal portion. The distal portion includes a transducer and an expandable anchor, which may be actuated to transition between a collapsed delivery state and an expanded deployed state where the anchor centralizes the transducer within the blood vessel. The transducer may be actuated to emit energy to reduce neural activity of the nerves surrounding the blood vessel. Systems and method are further provided for confirming that neural activity of the nerves surround the blood vessel has been sufficiently reduced.

Abstract: A system for determining orientation of a distal end of a catheter. The system includes a radial ultrasound system configured to generate images based on data received from a radial ultrasound probe. The system also includes a display device to present the generated images, a medical device, and a catheter system. The catheter system includes a flexible shaft having a first lumen configured to receive the radial ultrasound probe and a second lumen configured to receive the medical device, a cap portion having a longitudinal axis, and at least one orientation pin. The cap portion includes a third lumen configured to align with the first lumen, a fourth lumen configured to align with the second lumen, an exit port, and a ramp disposed between the fourth lumen and the exit port.

Abstract: A system screens, diagnoses, or monitors sleep disordered breathing of a patient. The system may include a nasal cannula, a conduit connected to the nasal cannula at a first end, an adaptor configured to receive a second end of the conduit and/or a portable computing device. The adaptor may be configured to position the second end of the conduit in proximity with a microphone of the portable computing device. Optionally, a processor may generate an indicator to guide placement of the adaptor for use. Such positioning may, in use, permit the microphone to generate a patient breathing sound signal via the adaptor for processor(s) of the device. The processor(s) may then process the breathing sound signal. The process may include detecting SDB events from an extracted and/or de-rectified loudness signal. The process may include computing a metric of severity of a respiratory condition of the patient using detected SDB events.

Abstract: The invention provides a catheter including: a first lumen adapted for draining a first fluid from a subject; a second lumen adapted for passing a second fluid through the second lumen; and a third lumen adapted for passing a third fluid through the third lumen such that the third fluid can exit the third lumen to bathe at least a part of an outside surface of the catheter. The invention further provides a kit and/or system including said catheter and method of use for said catheter.

Abstract: Provided herein are dual-lumen catheters, systems, and methods thereof. In some embodiments, for example, a catheter assembly configured for modifying intravascular lesions is provided including a core wire, a dual-lumen extrusion including the core wire, and a manifold disposed around a portion of the dual-lumen extrusion. The core wire includes a proximal end configured to vibrationally couple to an ultrasound transducer. The dual-lumen extrusion includes a first lumen and a second lumen. The core wire is disposed within the first lumen, and the second lumen is configured to accommodate a guidewire. The manifold is disposed around at least a skived proximal-end portion of the dual-lumen extrusion, wherein the skived portion includes the second lumen without the first lumen. In some embodiments, the catheter assembly further includes the ultrasound transducer. In some embodiments, a system console includes the ultrasound transducer.

Abstract: A working end of a catheter includes at least one therapeutic element, such as a resistive heating element, usable to deliver energy for ligating, or reducing the diameter of, a hollow anatomical structure. In certain examples, the catheter includes a lumen to accommodate a guide wire or to allow fluid delivery. In certain embodiments, a balloon is inflated to place resistive element(s) into apposition with a hollow anatomical structure and to occlude the structure. Indexing devices and methods are also disclosed for successively treating portions of the hollow anatomical structure. In certain examples, marks along the catheter shaft provide visual verification to the physician of the relative position of the therapeutic element of the catheter. Embodiments of indexing devices may include pairs of rings and/or hinged arms that move a catheter a desired indexed position between successive treatments.

Abstract: In some examples, a catheter may include an elongate body and a push assembly. The elongate body may include an inner liner defining an entry port into a lumen, and an outer jacket. The push assembly may an elongate member extending from a proximal portion to a distal portion, where a cross-section of the distal portion is D-shaped and tapers in a distal direction. Distal to a proximal end of the elongate body, a first portion of the elongate member may be positioned between a portion of the inner liner and a portion of the outer jacket, and proximal to the proximal end of the elongate body, a second portion of the elongate member may be positioned outside of the outer jacket and the inner liner.

Abstract: A sensing chip attached to a bandage monitors the healing process of a wound by detecting growth factors, thrombin and fibrinogen. The complementary metal-oxide semiconductor includes a functionalized working electrode, functionalized counter electrode and functionalized reference electrode. The healing progress is stimulated by generating oxygen in the wound.

Abstract: A sensor device is removably attachable to a drug delivery device. The sensor device comprises an array of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, which has a first movable element configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the path and to output a signal indicative of an amount of detected light. Circuitry is configured to receive the signals output from the optical sensors and, based on the received signals, determine information associated with a location along the path of the first movable element.

Abstract: A reentry catheter for crossing a vascular occlusion includes an elongate flexible tubular body, having a proximal end, a distal end and at least one lumen extending there through. A reentry zone on the tubular body includes at least two and preferably three sets of opposing pairs of axially spaced exit apertures in communication with the lumen. The apertures are rotationally offset from each other and aligned in a spiral pattern around the tubular body. A method of crossing a chronic total occlusion includes the steps of advancing the reentry catheter across the occlusion via a channel formed in the subintimal space, and advancing a guidewire via a selected exit port into the native lumen distally of the occlusion. The catheter may be removed, leaving the guidewire across the occlusion to guide further interventional devices.

Abstract: The invention comprises an indwelling medical device which is capable of delivering a therapeutic agent evenly along the length of the indwelling portion, including the outer wall, of the device.

Abstract: A catheter for radial artery access to the contralateral subclavian artery and internal mammary artery is disclosed. The catheter includes a preformed tubular hook element configured for aligning coaxially within the subclavian artery from a radial access. The tubular hook element includes a first arm connected to a second arm via a curved element, and a second arm connected, via a second curved element, to an elongated tubular body. Each curved element has an angle between approximately 90-130 degrees. The catheter can receive a second catheter and guide it to further advance the subclavian artery. The second catheter then extends past distal end of the catheter and advances into the internal mammary arteries for selective angiography and intervention. The two-catheter system allows angiography and intervention of the entire right and left upper extremities to be performed depending on the access from the left or right radial artery, respectively.

Abstract: A catheter assembly comprises a catheter (18), a needle (12) having a sharp distal tip disposed within the catheter (18), a catheter hub (14) connected to the catheter (18) having the needle (12) passing therethrough, the catheter hub (14) including a valve (38) that selectively permits or blocks a flow of fluid through the catheter (18), a valve actuator (54) that moves between a first position and a second position, and a return member (56) that returns the valve actuator (54) from the second position to the first position, and a needle protection member (176) that encloses the sharp distal tip of the needle (12).

Abstract: An enhanced flexibility catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end, and a side wall defining a central lumen. The side wall is formed from a plurality of adjacent tubular segments. At least one segment has a first end face inclined at a non normal angle to a longitudinal axis of the catheter. An adjacent segment has a second end face inclined at a complementary angle to form an inclined junction at the transition between the two segments. The transition serves to provide superior bending characteristics along the length of the catheter shaft.

Abstract: The present invention is directed to a dual lumen cannula configured to be inserted into a patient's body as simple as a single lumen cannula. The dual lumen cannula includes at least one inner lumen configured to be inserted into an outer lumen and connected via an inner lumen connection unit and an outer unit connection unit. Embodiments of the presenting invention further allow for the connection of at least one flow router to the other end of the inner lumen connection unit. When installed, the outer lumen is first inserted into the patient's body, followed by the insertion of the inner lumen into the outer lumen of the already cannulated patient until the inner lumen connector unit is in coupling contact with the outer lumen connector unit. Advantages of the inventive cannula presented herein include, among other things, reduction of external forces on the dual lumen cannula.

Abstract: In one embodiment, a device for in vivo tissue evaluation includes an elongated manipulator including an elongated proximal tube and an articulable distal portion, and a sensor provided at a distal end of the articulable distal portion, the sensor including a sensor head configured to be pressed against tissue and measure a reaction force of the tissue.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices and methods to guide delivery devices and instruments. Exemplary instrument guides, including for endoscopes as delivery devices for cryogen delivery catheters and to guide cryogen decompression tubes as instruments, and methods for use of such instrument guides for use in body lumens at treatment sites, are disclosed.

Abstract: A horseshoe-shaped guide catheter for stent angioplasty of the ductus arteriosus in newborn and infants with ductal-dependent cardiopathies, characterized by a long, straight, hollow first section merged at the distal end thereof to a second section formed by a curved portion shaped as a circle section with radius (Ra) of 7.5 mm to 9 mm, arc (b) of 180° to 280° and distance (d) between the tip of the second section and the straight part of the first section without deformations of 7 mm and 15 mm. The angioplasty makes it possible to insert one or more stents that keep the ductus open in extrauterine life, improving survival of the newborn and young infants, allowing weight gain and undergo corrective surgery a few months later with safer and with better outcomes.

Abstract: A persistent perfusion sheath assembly can be used for the passage of an intravascular medical device while maintain a flow passage in the vessel. The sheath assembly passes through an arteriotomy and can include a first lumen configured for the passage of a medical device, a second lumen configured to allow a flow of fluid from a location in the blood vessel upstream of the arteriotomy to a location downstream of the arteriotomy. The sheath assembly can further include a stylet, a sleeve or an additional sheath configured to selectively open and close the flow of blood between upstream and downstream of the arteriotomy. The sheath assembly can further include a closure device distal of the arteriotomy, the closure device configured to control blood flow through the arteriotomy.

Abstract: Catheters with weeping balloons can be used for various medical purposes. For example, in some embodiments provided herein weeping balloons are used for catheter visualization devices. In some embodiments, weeping balloons are used to deliver therapeutic agents. Weeping balloons can include openings of a selected size and shape through which a fluid gradually flows or “weeps.” The design of the openings can affect performance characteristics such as, but not limited to, fluid flow rate, tear resistance, and mitigation of counter-flow.

Abstract: An aortic perfusion catheter is an apparatus that is used during surgery for acute ascending aortic dissection to reduce postoperative injuries from profound hypothermia, ischemia, and reperfusion. The apparatus may include at least one main cannula, an inflation cannula, a drainage cannula, and a balloon tamponade. The at least one main cannula helps maintain blood perfusion to the body during the procedure to reduce postoperative injuries. The inflation cannula enables the selective inflation and deflation of the balloon tamponade to facilitate the insertion and removal of the balloon tamponade along with the at least one main cannula within the descending thoracic aorta. The balloon tamponade prevents blood flow into the operative area to maintain the operative area clear during the procedure. The drainage cannula enables the drainage of blood that may escape the balloon tamponade as well as other bodily fluids.

Abstract: A sutureless securing device for securing on an opening in a ventricular wall, includes: a hollow main body with an outer surface; a ring received at a first end of the hollow body, this ring being mobile along part of the outer surface of the hollow body; a tubular membrane covering the outer surface, whilst extending between the ring and the second end of the hollow body; a distal end of this tubular membrane, placed on the side of this second end, being self-expandable between a first configuration in which it has a tubular form, and a second configuration in which it defines a first flange extending radially, starting from the hollow body; the other end of this tubular membrane being able to be deformed by the displacement of the ring, such as to form a retention flange, the position of which can vary relative to the first flange.

Abstract: An infusion catheter system may deliver a therapeutic agent to a desired location in the body. The system may include an elongate catheter shaft having a proximal end region, a distal end region, a distal opening, and a lumen extending between the proximal end region and distal opening. The distal end region may include a coiled portion having a preformed coiled configuration including a plurality of helically wound rings. A plurality of apertures may be formed through a sidewall of the coiled portion. A guidewire may be configured to be slidably disposed within the lumen of the catheter shaft. The guidewire may include a proximal end region having a first cross-sectional dimension, an enlarged distal end region having a second cross sectional dimension greater than the first cross-sectional dimension, and an intermediate region disposed between the proximal end region and the distal end region.

Abstract: A dual lumen drainage cannula configured for use in a VA ECMO system includes a first drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the first drainage tube proximate to the distal end of the first drainage tube, and a second drainage tube having a proximal end, a distal end, and at least one aperture in at least one wall of the second drainage tube proximate to the distal end of the second drainage tube. The first drainage tube passes through the second drainage tube. The dual lumen drainage cannula also includes a sleeve positioned adjacent to an interior wall of the second drainage tube. The sleeve is formed of a flexible material so as to be expandable and collapsible within the second drainage tube.

Abstract: A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. The first cut shapes are configured to at least partially resist deformation in response to longitudinal compression and tension on the shaft and torsion on the shaft in a first circumferential direction. The second cut shapes are configured to at least partially resist deformation in response to longitudinal compression on the shaft and torsion on the shaft in both first and second opposite circumferential directions.

Abstract: A method of manufacturing a catheter assembly generally includes providing a catheter shaft having an outer layer and an inner reinforcing layer; removing at least a portion of the outer layer from a length of the distal end of the catheter shaft in order to expose a distal segment thereof; providing an inner jacket segment; axially engaging the inner jacket segment with an interior surface of the distal segment of the catheter shaft; providing an outer jacket segment around at least the exposed exterior region of the distal segment of the catheter shaft; and bonding the distal segment of the catheter shaft to the inner jacket segment and the outer jacket segment.

Abstract: Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

Abstract: A catheter that includes a tubular inner layer, a first reinforcing body that is wound around an outside in a radial direction of the inner layer, a second reinforcing body that is wound around the outside in the radial direction of the first reinforcing body, and an outer layer that covers the inner layer, the first reinforcing body, and the second reinforcing body, and the inner layer has a reduced diameter portion that is reduced in diameter from a proximal end side of the catheter toward a distal end side of the catheter on an inner peripheral surface of the inner layer, and a thickness of the outer layer between the first reinforcing body and the second reinforcing body is increased, at least partially from the proximal end side toward the distal end side, in the radial direction of the reduced diameter portion.

Abstract: A method is for controlling the operation of a medical apparatus. The method includes determining input data including patient data relating to a patient, operational status data relating to operational status of the medical apparatus, position data describing position of at least one of the wireless, handheld mobile operating device and the patient in relation to the medical apparatus, and workflow data describing at least one of a medical apparatus workflow and a current position in the medical apparatus workflow; determining, using an artificial intelligence analysis algorithm, at least one of a subsequent operating action of an operator of the wireless, handheld mobile operating device and prediction data describing an item of information needed next by the operator; and at least one of selecting and adapting a user interface to be displayed on the touch screen, based upon the prediction data and displaying the user interface on the touch screen.

Abstract: A dilator for sheathless access to a vessel of a patient having a tubular distal member with a skived portion on the proximal end and a proximal member with a skived portion on the distal end. The respective skived portions overlap at a transition region and form a rapid exchange port that communicates with the lumen of the distal member. The proximal member and the distal member may be secured together with transition tubing that is coaxially disposed over the distal and of the proximal member and extends over the skived portion of the distal member within a projected circumference of the distal member.

Abstract: A medical elongated body and a medical elongated body set are constructed in a way that expedites medical instrument insertion into a tubular body lumen via a valve body. The medical elongated body includes a tubular body insertable into a body lumen, a hub having an internal space communicating with a lumen of the tubular body and disposed in a proximal portion of the tubular body, a valve body disposed in the internal space and having an insertion portion, and a cap member that fixes the valve body in the internal space by being attached to the valve body and has a proximal opening portion to communicate with the internal space via the insertion portion. The cap member has a marker portion that guides a medical instrument inserted into the tubular body to the valve body. The marker portion has a color distinguishable from a periphery of the marker portion.