Abstract: An apparatus includes a catheter for an intrathecal drug delivery system and a stylet having a curved forward end. Preferably, the curved forward end has a shape in the form of a “J” or a “C.” Also preferably, the catheter has a distal end that conforms to the curved forward end of the stylet. Thus, the present invention provides a catheter having a blunt forward end that minimizes the risk of penetrating the substance of the spinal cord. Additionally, the curved forward end of the stylet can be formed of a springy material so that it straightens out during the processes of insertion through a guide needle and retraction from the needle.

Abstract: A wire includes a first wire section is of a first material and a second wire section is of a second material different from the first material. A joining section is adjacent both the first and second wire sections, the joining section comprising a first end and a second end. The first end of the joining section is of a material that is compatible with the first material of the first wire section and the second end of the joining section is of a material that is compatible with the second material of the second wire section.

Abstract: A catheter adapted for ablation, mapping, injection, and directional control by an external magnetic system has a catheter body, an intermediate section, and a tip section having a tip electrode configured with an omnidirectional distal end and a concentric needle port. The tip electrode houses a magnetic device and a position sensor arranged in an integrated configuration, wherein the configuration facilitates a path in the tip section for a component, including an injection needle, to extend through the tip section for extension and retraction with reduced stress and friction. The integrated configuration is an efficient use of space in the tip electrode that allows the tip section to carry both the position sensor for determining location and orientation of the tip section and the necessary volume of magnetic or magnetizable material to accomplish magnetic navigation.

Abstract: In at least one embodiment of the present invention, a catheter for insertion into a patient's body is provided. The catheter comprises an elongated member having a proximal portion extending to a distal portion. A lumen is formed through the proximal and distal portions. The elongated member is formed of a polymeric material including shape memory polymers having a first phase transition temperature and a second phase transition temperature that is less than the first phase transition temperature but is greater than about room temperature. The elongated member has a first configuration at about room temperature for insertion into the patient's body and self-configures to a second configuration at a first temperature of at least the second phase transition temperature for fluid communication with the patient's body. At least a portion of the lumen has a larger flow area in the second configuration than in the first configuration.

Abstract: The invention encompasses a catheter having an outer surface, a distal end, and at least one interior lumen, wherein the outer surface includes multiple aspiration passageways in fluid communication with an interior lumen. A preferred embodiment comprises multiple aspiration passageways formed into a helical pattern.

Abstract: Medical devices and methods are disclosed. An example method for accessing a body lumen may include providing a catheter system. The catheter system may include a catheter shaft having a lumen defined therein and an outer wall surface having a channel formed therein. A first guidewire may be disposed in the channel and a second guidewire may be disposed in the lumen. The method may also include advancing the catheter system through a body lumen to a location where the body lumen splits into a first section and a second section, advancing the first guidewire into the first section, and advancing the second guidewire into the second section, and advancing the catheter shaft along the second guidewire and into the second section. Advancing the catheter shaft along the second guidewire and into the second section may remove at least a portion of the first guidewire from the channel.

Abstract: An introducer sheath assembly comprises a tubular sheath member having a deflectable distal end portion and a sheath member lumen, a handle assembly including a steering mechanism for deflecting the distal end portion of the sheath member, and a hemostasis valve assembly. The hemostasis valve assembly includes a side port member configured to be connected to a fluid source for introducing fluid into the sheath member lumen. The side port member is axially rotatable relative to the handle assembly and the sheath member such that the side port member can remain rotationally fixed relative to the fluid source as the handle assembly and the sheath member are rotated relative to the fluid source. The side port member may also be made transparent to allow for easy visualization of air bubbles, and is also configured to allow for evacuation of any visualized air bubbles.

Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.

Abstract: A variable-stiffness guidewire system which comprises an elongated flexible guidewire. The guidewire has a body and a tensioning head coupled to the body. The tensioning head is slidably moveable with respect to a guidewire collar coupled to the body via a tensioning wire to adjust a stiffness of the guidewire. The guidewire includes one or more protrusions within a conduit of the guidewire collar which applies a frictional force to the tensioning wire to maintain the tensioning head a desired distance from the collar, thereby maintaining the desired stiffness in the guidewire. A tool can be utilized with the guidewire to engage the guidewire head and move the guidewire head a desired distance from the guidewire collar to achieve a desired stiffness.

Abstract: An optical guidewire system employs an optical guidewire (10), an optical guidewire controller (12), a guide interface (13) and an optical connector (15). The optical guidewire (10) is for advancing a catheter (20) to a target region relative to a distal end of the optical guidewire (10), wherein the optical guidewire (10) includes one or more guidewire fiber cores (11) for generating an encoded optical signal (16) indicative of a shape of the optical guidewire (10). The optical guidewire controller (12) is responsive to the encoded optical signal (16) for reconstructing the shape of the optical guidewire (10). The guidewire interface (13) includes one or more interface fiber core(s) (14) optically coupled to the optical guidewire controller (12). The optical connector (15) facilitates a connection, disconnection and reconnection of the optical guidewire (10) to the guidewire interface (13) that enables a backloading the catheter (20) on the optical guidewire (10).

Abstract: A rapid exchange catheter comprises a guide wire lumen including a substantially sealed portion in which a lumen wall extends around an entire periphery thereof and a channel portion including a channel opening the lumen to an exterior of the catheter, wherein a width of the channel is less than a maximum width of the channel portion. A guide wire ramp extends into the channel portion, with the ramp extending further into the lumen of the channel portion as a distal end of the ramp is approached.

Abstract: A method includes providing an elongated probe having a longitudinal axis and a distal end, and capable of rotation of the distal end about the longitudinal axis in mutually opposite first and second directions. While an operator manipulates the probe within a body of a patient, the rotation that is applied to the distal end is sensed automatically. An alert is issued to the operator upon sensing that the rotation is in the second direction, but not when the sensed rotation is in the first direction.

Abstract: Systems are described herein that improve control of a shapeable or steerable instrument using shape data. Additional systems use such shape data for improved mapping or adjusting models of the instrument. Such systems include robotic medical systems for controlling a shapeable instrument within an anatomical region having a controller, one or more actuators, and a localization system for guiding one or more shapeable instruments.

Abstract: A catheter adapted for use in a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal a mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for deflection of the catheter via a first and second puller wire responsive to a deflection assembly and manipulation of distal assembly via a third puller wire responsive to a linear motion actuator assembly. The linear motion actuator assembly includes a pair of user interface knobs, a body to which a proximal end of the third puller wire anchored, and a pair of arms that movably suspends the body and transmits longitudinal travel of the knobs to the body in a manner that multiples the travel of the body relative to the travel of the knobs.

Abstract: A medical catheter assembly includes a catheter hub, an elongate catheter member extending from the catheter hub and having at least one longitudinal lumen for passage of fluids, an extension tube extending from the catheter hub and defining an internal lumen in fluid communication with the at least one longitudinal lumen of the catheter member and a clamp positionable about the extension tube. The catheter hub defines a reduced profile to facilitate passage of the catheter hub through a surgical tunnel. The clamp includes first and second clamp sections and defines a longitudinal clamp axis. The clamp has a longitudinal opening for passage of the extension tube and a movable member adapted to move from a first position to a second position to substantially close the internal lumen. The first and second clamp sections are separable to facilitate transverse positioning of the clamp sections about the extension tube.

Abstract: A multi-functional wire guide assembly includes an elongate tubular housing having a length and defining a lumen extending from an open proximal end of the elongate tubular housing to an open distal end of the elongate tubular housing. A first mandril is positioned within the lumen, extends a majority of the length of the elongate tubular housing, and has a fixed position relative to the elongate tubular housing. A second mandril is positioned within the lumen, has a length greater than the length of the elongate tubular housing, and is axially movable relative to the elongate tubular housing. The multi-functional wire guide assembly has a first configuration in which a distal tip of the second mandril is proximally spaced from a distal segment of the elongate tubular housing and a second configuration in which the distal tip of the second mandril is axially aligned with the distal segment.

Abstract: A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

Abstract: A delivery system assembly includes an elongate outer tube, an elongate inner member extending within a lumen of the outer tube, and an articulation sheath surrounding the outer tube between a handle of the assembly and a distal-most portion of the outer tube. The outer tube is longitudinally moveable within the sheath; and an inner diameter of the sheath is preferably smaller than that of the handle and the distal-most portion of the outer tube. Navigation of the assembly through a venous system, for deployment of an implantable medical device, is facilitated by deflection of the sheath, to orient a distal-most portion of the outer tube, within which an entirety of the medical device is contained/loaded, and by subsequent advancement of the distal-most portion, with respect to the sheath, to move the distal end of the inner member, along with the contained/loaded device into proximity with a target implant site.

Abstract: A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

Abstract: A guidewire includes a core wire, a coil body that covers the core wire, a tip portion that fixes a distal end of the core wire to a distal end of the coil body, and a resin layer formed on an outer peripheral surface of the core wire. A gap is provided between an outer peripheral surface of the resin layer and an inner peripheral surface of the coil body, so that the resin layer and the coil body are not in contact with each other.

Abstract: Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position.

Abstract: A catheter assembly includes a handle assembly, and a catheter body coupled with the handle assembly, where the catheter body extends to a deflectable distal end portion, and the deflectable distal end is controllable by a flexible element. A lever actuator member is operatively coupled with the flexible element, and movement of the actuator member provides for movement of the flexible element.

Abstract: A medical device assembly may include an elongated guidewire, an elongated flexible tubular membrane disposed about the guidewire, and a percutaneous medical device, wherein the membrane is configured to permit the percutaneous medical device to pass through the lumen. A method of advancing a medical device through a vessel may include advancing an elongated flexible tubular membrane through the vessel to a treatment site, inserting the medical device into the membrane, and advancing the medical device through the membrane while maintaining the membrane in an axially stationary position relative to the vessel.

Abstract: The present disclosure relates generally to medical tubing and methods of manufacturing medical tubing. In particular, the present disclosure relates to medical catheters and methods of manufacturing medical catheters, including rapid exchange catheters. In some embodiments, catheters of the present disclosure have varying stiffness or rigidity along their length. In some embodiments, catheters of the present disclosure have a guiding portion with a different color than a main body portion. In some embodiments, catheters of the present disclosure have wrapped filaments imbedded therein to provide structural integrity and desired handling characteristics for the catheter. Additional aspects of the present disclosure are apparent from the detailed description.

Abstract: Various embodiments of the present invention generally relate to safety neural injection systems and related methods of use comprising a cannula, with or without a side port, and a stylet, defined by a first inside diameter, a first outside diameter, a first length, and an open distal end in fluid communication with the inside and outside of the hollow cannula wherein the medicament is administered with the stylet inserted at least partially within the cannula.

Abstract: Interventional catheter assemblies that operate over a guide wire and incorporate guide wire management systems are disclosed. Specifically, a guide wire buffer zone is provided between a proximal end of the interventional catheter and the guide wire clamp that accommodates variable lengths of exposed guide wire in an unrestrained condition when the guide wire is clamped, allowing the distal end of the operating catheter to be advanced and retracted over the distal end of the guide wire without repositioning and reclamping the proximal end of the guide wire. The configuration of the guide wire buffer zone may be adjusted prior to or during an intervention based on the anticipated range of axial motion of the catheter and operating head relative to the guide wire.

Abstract: An intravascular medical device including an elongated member configured to be advanced along a vascular path of a patient, the elongated member having opposite first and second ends, the first end and second ends both being adapted for intravascular insertion, and the first end having a different structure than the second end. The elongated member has sufficient flexibility to be advanced through a human vasculature. Preferably, the first and second ends are adapted to have different operating characteristics. Depending on the operating characteristics needed for a particular procedure, a physician can insert either the first end portion or the second end portion of the elongated member into the patient's vasculature.

Abstract: A steerable rotate-to-advance device for accessing a bodily passageway, said steerable rotate-to-advance device comprising: an inner flexible tube having a distal end and a proximal end, a longitudinal axis extending between said distal end and said proximal end, and a lumen extending from said distal end to said proximal end; an outer flexible tube having a distal end and a proximal end, a longitudinal axis extending between said distal end and said proximal end, and a lumen extending from said distal end to said proximal end; the outer flexible tube being disposed coaxially over the inner flexible tube and being rotatable with respect thereto; an external thread disposed over said distal end of said outer flexible tube, said external thread having a sufficient structural integrity, and a sufficient surface profile, such that when said outer flexible tube is disposed in a bodily passageway, rotation of said outer flexible tube about said longitudinal axis will result in longitudinal motion of said outer f

Abstract: A catheter has a control handle with at least an outer thumb control and an inner second thumb control. A longer puller wire has a distal end anchored at or near a distal end of distal deflectable portion. A shorter puller wire has a distal end anchored at or near a distal end of the proximal deflectable portion. For the shorter puller wire, a shorter compression coil has a distal end at or near a proximal end of the intermediate deflectable section. For the longer puller wire, a longer compression coil has a distal end at or near a distal end of the shorter puller wire. The inner and outer thumb controls include engagement members releasable by rotation of one thumb control relative to the other. When disengaged, the thumb controls each can be moved longitudinally relative to each other. When engaged, the thumb controls are coupled together for longitudinal movement as a single unit relative to the control handle.

Abstract: A surgical instrument for grasping and controlling a guide wire includes a male member having a longitudinal slit in communication with an inner hollow bore and a female member having a longitudinal slit in communication with an inner chamber. The male member is rotatably engageable within at least a portion of the female member. A method of threading a guide wire into a surgical instrument includes engaging a male member within a female member, rotating the male member relative to the female member until a longitudinal slit of the male member is aligned with a longitudinal slit of the female member; inserting a guide wire through the slits and into an interior of the male member and female member; and rotating the male member relative to the female member until the slits of the male member and female member are not aligned, trapping the guide wire within the surgical instrument.

Abstract: A catheter assembly comprises a catheter having a wall at least partially defining a lumen. The lumen communicates with an opening in an exterior catheter surface at a distal end of the catheter. A lengthwise portion of the wall is made of a resilient material and is longitudinally extensible. The lengthwise portion of the wall has a diameter that is reduced when the lengthwise portion of the wall is longitudinally extended. The diameter of the lengthwise portion of the wall increases from a reduced condition when the lengthwise portion of the wall resiliently returns from a longitudinally extended condition.

Abstract: System and components for inducing pleurodesis while minimizing likelihood of tissue damage from direct application of pleurodesis-enhancing materials. A tube device is provided that is configured to elute pleurodesis-enhancing material. The device includes one or more features configured to prevent or lessen the likelihood that the pleurodesis-enhancing material comes into direct and concentrated contact with patient tissue when a distal length of the device is disposed indwelling a patient.

Abstract: The disclosure provides a catheter for positioning in a contralateral femoral approach in highly angulated iliac bifurcations. The catheter comprises an elongate shaft, an adjustable element, and a wire entrance port on the elongate shaft. The elongate shaft has a proximal portion, an intermediate portion, a curved portion, and a distal portion. The curved portion connects the intermediate portion and the distal portion. The adjustable element is configured to encompass the distal portion and the intermediate portion together in a closed position. The adjustable element can be removed away from the distal portion permitting the distal portion in an open position. The wire entrance port is disposed in the intermediate portion near the curved portion. The distal portion is biased to be spaced away from the intermediate portion in the open position. The adjustable element is connected to an operating wire configured to advance and retreat through the wire entrance port.

Abstract: The long nose manipulatable catheter includes a main lumen, a wire lumen with a push-pull wire therethrough, and a flexible joint region. The catheter section includes a control including a handle and a wire control member engaging the push-pull wire for manipulating the flexible joint region. The push-pull wire may be tapered, having a proximal portion of a first diameter and a smaller diameter distal portion. A coil may be placed around the smaller diameter to prevent buckling of the smaller diameter portion. A strapping coil may also disposed around the outside of the catheter, and an outer covering may be disposed around the strapping coil. An outer covering of a mesh may also be disposed around the distal tip of the catheter.

Abstract: A method for visualizing the interior of a bodily passageway comprising providing a system comprising a plurality of concentric telescoping shafts; visualization apparatus disposed within the telescoping shafts; and a helical thread disposed on the exterior of the telescoping shafts, the helical threads having a sufficient structural integrity and surface profile such that when the telescoping shafts are disposed in the passageway, rotation of the telescoping shafts induces a relative movement between the telescoping shafts and the passageway; wherein the telescoping shafts are configured to be selectively coupled together and de-coupled from one another; inserting the system into the passageway; rotating the telescoping shafts so as to draw the passageway onto the telescoping shafts in a pleating fashion; de-coupling the telescoping shafts; rotating the innermost telescoping shaft so as to draw the passageway onto the innermost telescoping shaft in a pleating fashion; and visualizing the interior of the pass

Abstract: An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length.

Abstract: A method for visualizing the interior of a bodily passageway comprising providing a visualization system comprising a tube, visualization apparatus disposed within the tube, and a deformable helical thread disposed on the exterior surface of the tube, the deformable helical thread being transformable between a first configuration wherein the deformable helical thread comprises a reduced profile and/or a reduced rigidity and a second configuration wherein the deformable helical thread comprises an expanded profile and/or increased rigidity; inserting the visualization system into the bodily passageway at a location remote from the site which is to be visualized, with the deformable helical thread being in its second configuration; rotating the tube so as to induce relative movement between the passageway and the tube, whereby to move the visualization apparatus and the site which is to be visualized closer together; and using the visualization apparatus to visualize the interior of the passageway.

Abstract: Methods and devices for providing improved ultrasound visibility of medical devices intended for intravascular use are described. The inclusion of gas/solid boundary regions within a medical devices improves the resolution of the device under ultrasound visualization. Gas/solid boundary regions may be provided through the use of embedded gas-filled microlumens, microwells, or enclosed pockets within the medical device.

Abstract: An apparatus for control of a procedure, comprising: a communications interface; a control console, wherein the control console is adapted to provide control commands via the communications interface to at least one of: at least one imaging device or at least one medical instrument used to perform the procedure; and, at least one radiation shield attached to the control console and positioned between the control console and a patient on which the procedure is being performed, wherein the apparatus is separately movable from at least one of the at least one imaging device, the patient or the at least one medical instrument.

Abstract: A steerable tube (100), comprising a hollow elongate tubular member (1) having a proximal end (2), distal end (3), a wall surface disposed between said proximal (2) and distal end (4), a bend-resistive zone (6) flanked by a proximal bendable zone (4) that forms a controller and a distal bendable zone (5) that forms an effector that moves responsive to movements of the controller, whereby the wall of the tubular member (1) in the bend-resistive zone (6) comprises a structure that is a plurality of longitudinal slits (7), forming a plurality of longitudinal strips (8, 8?), the wall of the tubular member (1) in the proximal bendable zone (4) and the distal bendable zone (5) comprises a structure that is a plurality of longitudinal wires (9, 9?, 10, 10?), at least one strip (8) is in connection with a wire (9) in the proximal bendable zone (4) and a wire (10) in the distal bendable zone (5), such that translation by said wire (9) in the controller is transmitted via the strip (8) to said wire (10) in the effector

Abstract: A surgical drain and method for using the same. The surgical drain comprises a first end, which may be sized for placement within an organism. The first end features a plurality of segments, each labeled with an alphanumeric character. The first end may be cut at a line between two of the segments. The alphanumeric character at the terminal end of the first end after cutting is recorded prior to placing the drain within the organism. When removing the drain, the recorded alphanumeric character is compared with the character at a terminal end of the first end of the surgical drain. Thus, a treating professional can ensure that no portion of the surgical drain is left within the wound, preventing infection due to a foreign object left within the organism.

Abstract: A feeding tube is configured for nasal insertion and advancement to the jejunum of a patient. The tube has a plurality of projections disposed along the surface of the distal tube portion for promoting advancement of the tube along the GI tract by peristaltic contractions. The tube includes first and second strings. The first string is aligned along the tube such that upon exertion of a pulling force on the first string, the distal end of the tube flexes in a direction of the force. The second string is aligned such that upon exertion of a pulling force on the second string, the tube is withdrawn from the GI tract responsive to the force. A snare may be provided for capturing the second string to promote withdrawal of the tube through the mouth of the patient.

Abstract: A wire guide grabbing mechanism includes an elongate mandrel having a proximal and distal mandrel end, and a grabber irreversibly attached to the mandrel. The grabber includes a plurality of struts arranged in a reticulated pattern and a plurality of openings defined by the plurality of struts. The grabber is adjustable between an expanded configuration at which the plurality of struts are spread out relative to one another and a contracted configuration at which the plurality of struts are condensed, such that a wire guide may be enmeshed by the grabber in the contracted configuration. Related methodology is also disclosed.

Abstract: An interventional catheter assembly comprises an operating head for removing obstructive material from a target site in a body lumen or cavity and at least one aspiration port located proximal to the operating head and penetrating the catheter assembly, the aspiration port being in communication with a sealed lumen that communicates with a vacuum system for withdrawing aspirate fluid and obstructive material from the target site. The interventional catheter incorporates an elongated guidewire lumen bushing extending proximally from a distal region of the operating head to reduce the clearance between the guidewire and the internal surface of the guidewire lumen during operation of the interventional catheter. This feature restricts entry of fluid and debris into the guidewire lumen and promotes maintenance of consistent and high aspiration pressure and volume during operation of the aspiration system and interventional catheter assembly.

Abstract: A catheter includes a handle, a catheter sheath and a stylet having a shaped distal part received within the catheter sheath. The catheter further has a shape adjustment mechanism including a stylet carrier displaceably carried by the handle and a shape adjuster in the form of a collar rotatable about the handle. Rotational movement of the shape adjuster imparts a motion to the stylet carrier to adjust the shape of the distal part of the stylet.

Abstract: A catheter handle includes a handle body having a proximal end and a distal end and a passage extending between the proximal end and the distal end. The handle body comprises a plurality of shell parts that can be separated to access an interior of the handle body. The handle further includes a connector mounted at the proximal end of the handle body and a strain relief arranged at the distal end, the strain relief and the connector being removably arranged relative to the handle body.

Abstract: The subject matter relates a catheter having a helical or spiral tip defining an aspiration port for removing obstructions from blood vessels.

Abstract: A sheath for a medical instrument includes an elongate body extending from a proximal end to a distal face. The elongate body may be configured to axially extend from a first length to a second length greater than the first length. The sheath may include a first hollow lumen extending from a first end proximate the proximal end to a second end proximate the distal face, and a second hollow lumen extending from the proximal end to the distal face. The second lumen may be open at the distal face. The sheath may also include a transparent window positioned at the second end of the first lumen to seal the first lumen at the second end. The transparent window may be configured to transmit light therethrough.

Abstract: A guide wire insertion aid for attaching onto a proximal end of a catheter or an implantable electrode line and for facilitating the insertion of a guide wire, formed as a horn- or funnel-shaped body which has a tubular fixing section and an expanding section extending therefrom, wherein the fixing section has an inner wall without contour and is slotted and elastically expandable at least over the larger portion of its longitudinal extension.

Abstract: Guide wire devices and methods for their manufacture. The guide wire devices described herein include an elongate guide wire member that includes at least one section fabricated from a nickel-titanium (Ni—Ti) alloy that exhibits an elevated plateau stress and a narrowed stress hysteresis profile (e.g., a plateau stress of about 500 MPa to about 820 MPa and a stress hysteresis width in a range from about 250 MPa to about 80 MPa). Raising the plateau stress and narrowing the stress hysteresis width of Ni—Ti used in a guide wire device can significantly improve the steerability of the guide wire device while maintaining the flexibility, durability, and kink resistance that is typical of superelastic Ni—Ti alloys.