Abstract: Different embodiment programmable pumps including multiple reservoirs are disclosed, as are methods of utilizing same. The pumps generally include at least two reservoirs and means for dispensing active substances housed in each at varying flow rates.

Abstract: A system and a method for distending a body tissue cavity of a subject by continuous flow irrigation by using two positive displacement pumps, such as peristaltic pumps, one pump on the inflow side and another pump on the outflow side, such that the amplitude of the pressure pulsations created by the positive displacement pumps inside the tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method of reducing the frequency of the said pressure pulsations. The present invention also provides a method for accurately determining the rate of fluid loss, into the subject's body system, during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors.

Abstract: A fluid delivery device includes a first housing and a second housing removably connected to the first housing. The fluid delivery device further includes an input line operatively connected to a fluid source that is external to each of the first housing and the second housing. A fluid reservoir is operably connected to the input line, and an output line is operably connected to the fluid reservoir. A pump is configured to facilitate a flow of fluid from the input line to the fluid reservoir and from the fluid reservoir to the output line. The fluid delivery device further includes a motor operably connected to the pump, a user interface, and a power source operably connected to the motor and to the user interface.

Abstract: A closed-loop method for insulin infusion overnight uses a model predictive control algorithm (“MPC”). Used with the MPC is a glucose measurement error model which was derived from actual glucose sensor error data. That sensor error data included both a sensor artifacts component, including dropouts, and a persistent error component, including calibration error, all of which was obtained experimentally from living subjects. The MPC algorithm advised on insulin infusion every fifteen minutes. Sensor glucose input to the MPC was obtained by combining model-calculated, noise-free interstitial glucose with experimentally-derived transient and persistent sensor artifacts associated with the FreeStyle Navigator® Continuous Glucose Monitor System (“FSN”).

Abstract: The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir with a repair catheter operably attached; a flow control device disposed between the sealant reservoir and the repair catheter, and the flow control device responsive to a flow control signal; a heart phase detector generating a diastole phase signal; an injection switch generating a injection signal; and a flow controller responsive to the diastole phase signal and the injection signal, and generating the flow control signal. A method of sealing a perivascular leak comprises identifying the perivascular leak; inserting a repair catheter to the perivascular leak; injecting sealant at the perivascular leak; and removing the repair catheter. The sealant can be injected when the heart is in diastole to sweep the sealant into the perivascular leak.

Abstract: A wearable infusion pump assembly includes a reservoir for receiving an infusible fluid, and an external infusion set configured to deliver the infusible fluid to a user. A fluid delivery system is configured to deliver the infusible fluid from the reservoir to the external infusion set. The fluid delivery system includes a volume sensor assembly, and a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the volume sensor assembly. The volume sensor assembly is configured to determine the volume of at least a portion of the quantity of fluid. The fluid delivery system further includes at least one optical sensor assembly configured to sense the movement of the pump assembly, a first valve assembly configured to selectively isolate the pump assembly from the reservoir, and a second valve assembly configured to selectively isolate the volume sensor assembly from the external infusion set.

Abstract: The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 20, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a handpiece 50 applied to a surgical area for infusing irrigation fluid and for aspirating a biological material, conduits 60 and 62 connecting the handpiece to each of the source of irrigation fluid and the collection cassette and means 70 for isolating the pump from the handpiece to prevent creation of vacuum within the conduit 62 and the collection cassette 30 after receiving a stop signal.

Abstract: There are cases where a fluid transport apparatus cannot accurately discharge a set discharge amount of fluid, due to individual differences in components of the fluid transport apparatus, such as the diameter of an opening of an elastic tube. Therefore, in a fluid transport apparatus including a fluid transport cartridge and a fluid transport driving unit that are separable from each other, the fluid transport driving unit comprises a driving section that causes a drive mechanism to operate to transport fluid filling a transport path of an attached fluid transport cartridge to a discharge opening of the transport path; a receiving section that receives a characteristic value measured in advance for each of a plurality of the fluid transport cartridges; and a control section that controls the driving section based on the characteristic values received by the receiving sections.

Abstract: A device for dispensing fluid to a patient and indicating a fluid flow condition. The device includes a reservoir configured to provide a source of fluid under pressure. A continuous flow path in fluid communication with the source of fluid provides a continuous and substantially constant flow rate of fluid from the source to a patient. The device further includes at least one pre-biased indicator in fluid communication with the continuous flow path. The pre-biased indicator is configured to provide a discrete visual signal that the pressure of the fluid in the continuous flow path is different from a predetermined level of pressure, thereby indicating a fluid flow condition.

Abstract: An injection device for injecting a fluid into an organism, in particular a human or animal body, which can comprise a fluid providing section including a container for storing the fluid and a supply means for supplying the fluid. The fluid injecting section for injecting the fluid provided by the fluid providing section into the organism includes a catheter means and is characterized by the fluid injecting section being provided with a pressure recognition arrangement which can be located close to and/or in the catheter means for detecting a pressure increase and/or a pressure loss.

Abstract: A pump for administering an agent to a patient includes a housing, a syringe seat, and a bumper. The syringe seat is coupled to the housing. The bumper is coupled to the housing adjacent to the syringe seat.

Abstract: The invention relates to a system for administring drug to a Parkinson's disease patient comprising (a) a drug; (b) a storing bag for the drug; (e) a pump for administering the drug; (d) a pump controller for controlling the pump activity, the pump controller having access to a correlation of a first parameter tx and a second parameter At, and to the current first parameter tx, wherein the first parameter tx is correlated with a certain activity of the patient and the second parameter At is correlated with a dosage of the drug and the pump controller controls the pump activity In dependence of the first parameter tx and the correlation, and/or wherein the system comprises (e) a storing hag the drug suitable for pre-filling and long-term oxidations-free storage having a multi layer wall with the internal layer made of EVA or cyclic, polyolefines and at least one further layer made of EVOH.

Abstract: The invention relates to an auto-injector (A) for administering a dose of a liquid medicament, comprising of a substantially tubular front-end device adapted to contain a syringe with an injection needle and a barrel containing the dose of the medicament and comprising a needle shroud adapted to rest on the skin of a patient receiving an injection and a reusable back-end device comprising of a housing, a plunger connected to or adapted to engage a stopper providing a fluid tight seal for a distal end of the barrel, a motor for displacing the plunger connected to the stopper, wherein the front-end device is attachable to the back-end device, wherein the needle shroud is slidably arranged with respect to the injection needle and wherein an interlock switch is capable of detecting an axial position (PA, PR) of the needle shroud.

Abstract: A blood volume control method has been developed including: monitoring a condition of a patient (such as hematocrit (Hct)), wherein the condition is indicative of blood volume in the patient; automatically determining that the condition indicates a low blood volume in the patient; automatically infusing an infusion solution into the patient in response to the determination of a low blood volume, and automatically adjusting the infusion to maintain the monitored condition at a predetermined value.

Abstract: An injection device including at least one sensor for detecting an operating process of the injection device, an electronic circuit connected to the sensor for establishing the beginning and elapsed time of a service life, based on one or more sensor signals, and an output device connected to the circuit for providing a signal indicating the end of the service life. The invention encompasses a method for determining a service life of an injection device, wherein the beginning of the service life is established by one or more sensors for detecting an operating process of the device, a signal is generated which signals the end of the service life, and at least one of an optical, acoustic or tactile output device is associated with the injection device for providing a signal which indicates the end of the service life.

Abstract: An in-joint pump and control device comprising a pump and an in-joint sensor. The pump is configured to convey fluid to a body joint surgical site. The pump has an algorithm associated therewith to make calculations and to assist in controlling the operation of the pump. The in-joint sensor is operatively associated with the pump by at least a communication member. The in-joint sensor comprises a sheath, an integration member attached to the sheath, a pressure sensor connected to the integration member, and a temperature sensor adjacent the sheath. The pressure sensor is adapted to provide pressure information to the pump via the communication member. The temperature sensor is also adapted to provide temperature information to the pump via the communication member.

Abstract: Devices, systems and methods are provided for drug delivery and the monitoring thereof.

Abstract: A medical treatment administration system for delivering a medical treatment to a patient. The system has a medical device, an electronic processor coupled to the medical device, and a sensor coupled to the processor. The sensor receives one or more signals which it transfers to the processor. The signals can be derived from the patient's physiological condition and/or the environment of the patient. The processor receives the signals and performs a calculation of the signal. Based on the result of the calculation, the processor regulates the distribution of medical treatment to the patient over a period of time.

Abstract: A blood sugar level control system for measuring a blood sugar level and administering insulin into a body. The blood sugar level control system includes a blood sugar measuring device having a first wireless data transmitting part to transmit data relating to the blood sugar level; an insulin dispensing device having a wireless data communication unit including a second wireless data transmitting part to transmit data to a second blood sugar measuring device, and a wireless data receiving part to receive data from the first wireless data transmitting part and the second blood sugar measuring device; and an attachment mechanism to couple the insulin dispensing device and the blood sugar measuring device so that the blood sugar measuring device is movable, without separating from the insulin dispensing device at least three specific positions.

Abstract: Systems and methods are provided which enable communications to be initiated locally relative to an individual's developing physiological condition and remotely as the condition requires. Physiological sensors and associated medical delivery systems can be coupled to a unit wearable by an individual which can provide various audible or visual outputs and one or more manual inputs indicative of the individual's condition. A global positioning unit can be incorporated so that condition information as well as location information can automatically be provided, wirelessly, to a remote monitoring system for follow up as needed.

Abstract: Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

Abstract: Apparatus are provided for motor control systems and related medical devices. In one embodiment, a control system includes a motor having a rotor, a sensor to obtain a measured displacement that is influenced by rotation of the rotor, and a control module coupled to the sensor. The control module adjusts a duty cycle for a modulated voltage applied to the motor in response to a difference between an expected displacement and the measured displacement. The expected displacement is influenced by or otherwise corresponds to a commanded rotation of the rotor.

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

Abstract: A fluidic media detection system for detecting a presence of fluidic media includes a first housing portion adapted to be carried by a user; a second housing portion configured to be selectively operatively engaged with and disengaged from the first housing portion, the second housing portion for supporting a reservoir having an interior volume for containing fluidic media; a fluid conduit supported by one of the first housing portion and the second housing portion for providing fluid communication between the reservoir and the user when the first housing portion and the second housing portion are operatively engaged; and at least one interactive element, positioned near a portion of the fluid conduit, that interacts with the fluidic media when the fluidic media is present in the fluid conduit.

Abstract: Apparatus are provided for motor control systems and related medical devices. In one embodiment, a control system includes a motor having a rotor, a modulation module coupled to the motor, and a control module coupled to the modulation module. The modulation module generates a modulated voltage that is applied to the motor and rotates the rotor to deliver fluid via a fluid path. The control module adjusts a duty cycle of the modulated voltage to achieve a commanded rotation of the rotor and detects an occlusion condition in the fluid path based on the duty cycle.

Abstract: Apparatus are provided for motor control systems and related medical devices. In one embodiment, a control system includes a motor having a rotor, a modulation module coupled to the motor, and a control module coupled to the motor and the modulation module. The modulation module generates a modulated voltage that is applied to the motor, and the control module adjusts a duty cycle of the modulated voltage to achieve a commanded rotation of the rotor and detects a degradation condition based on the duty cycle.

Abstract: Fluid management systems and methods of operating fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.

Abstract: The present invention is directed to a dialysis system with a disconnection monitor for determining if a blood line connection to a patient has been disconnected. It includes a blood circuit in fluid communication with a patient and a dialysis circuit, a pressure transducer for generating a signal indicative of a pulse signal in the blood circuit, a cardiac reference signal generator for generating a signal indicative of the patient's pulse and a disconnection monitor. The disconnection monitor includes a pressure transducer data receiver for receiving the signal indicative of the pulse signal in the blood circuit, a cardiac reference signal receiver for receiving the signal indicative of the patient's pulse, and a processor for cross-correlating the signal indicative of the pulse signal in the blood circuit and the signal indicative of the patient's pulse to generate data indicative of a disconnection of the blood line connection to the patient.

Abstract: A portable therapeutic fluid delivery device with a flow detector comprising a heating element and two temperature sensors is presented. Upon activation of the heating element, a flow condition of the fluid inside the delivery tube is determined based on a signal provided by the temperature sensors. A temperature gradient within the therapeutic fluid is detected. The determined flow condition can be one of: air bubbles within the delivery tube, occlusion within the delivery tube, or leakage within the delivery tube. The device can have two parts, for example, a reusable part and a disposable part. Upon pairing of these parts, the heating element and the temperature sensors touch the delivery tube.

Abstract: A method of dispensing fluid includes three processes. A first one of these processes includes pumping fluid into a resilient variable-volume dispensing chamber. The dispensing chamber is in series with a normally present finite fluid impedance and an output. The impedance is sufficient so as to cause expansion of the dispensing chamber as it receives pumped fluid even while some fluid flows through the output. Another one of these processes includes repeatedly measuring a parameter related to volume of the dispensing chamber over time. A third one of these processes includes controlling the pumping of fluid based on repeated measurements of the parameter to produce a desired fluid flow through the output. A corresponding system for dispensing fluid implements these processes.

Abstract: Apparatus are provided for motor control systems and related medical devices. In one embodiment, a control system includes a motor having a rotor, a modulation module coupled to the motor, and a control module coupled to the motor and the modulation module. The modulation module generates a modulated voltage that is applied to the motor, and the control module adjusts a duty cycle of the modulated voltage to achieve a commanded rotation of the rotor and detects a degradation condition based on the duty cycle.

Abstract: A metabolite monitoring system comprising a microdialysis probe including a semi-permeable membrane and a probe flow path passing from an inlet through a sensing volume adjacent to said semi-permeable membrane to an outlet, a fluid delivery device for delivering dialysate to said inlet; and a metabolite monitoring system associated with said outlet for monitoring a concentration of at least one metabolite in said dialysate from said microdialysis probe, wherein said fluid delivery device is configured to deliver a pulsed flow of said dialysate to said inlet.

Abstract: A drug delivery device is provided comprising a container, a first product and a second product. The device is configured to mix the first product and the second product with each other within the container for forming a drug mixture. The device is further configured for dispensing the drug mixture. The device comprises a mixing member. The device is switchable from a first state, in which the first product and the second product are separated, into a second state, in which the first product and the second product are mixed. The mixing member is configured to exert a force onto the container in order to move the container to mix the first product and the second product with each other. Furthermore, a method for maintaining a predetermined property of a drug mixture to be dispensed from a drug delivery device is provided.

Abstract: An electronically and remotely controlled pill (500) or medicament delivery system is provided. The pill (500) includes a housing (102); a medicament reservoir (104) for storing a medicament; an electronically controlled release valve or hatch (106) for dispensing one or more medicaments stored in the medicament reservoir (104) while traversing the gastrointestinal tract; control and timing circuitry (108) for opening and closing the valve (106); and a battery (109). The control and timing circuitry (108) opens and closes the valve (106) throughout a dispensing time period in accordance with a preset dispensing timing pattern which is programmed within the control and timing circuitry (108). RF communication circuitry receives control signals for remotely overriding the preset dispensing timing pattern, reprogramming the control and timing circuitry (108), or terminating the dispensing of the medicament within the body.

Abstract: A blood access device including a fluid conduit configured to convey a flow of fluid to a target vessel, a second lever element pivotally and resiliently connected to a first lever element such that it may move from a first position to a second position. A biasing force is exerted on the second lever element for moving it from the first position to the second position, and a blocking member may be activated by the second lever element, such that a flow of fluid is decreased when the second lever element is moved from the first position to the second position. The lever elements are configured to be fixed to the target vessel when the second lever element is in the first position, and the second lever element moves to the second position and activates the blocking member if the fixation is at least partially lost.

Abstract: A differential pressure based flow sensor assembly and method of using the same to determine the rate of fluid flow in a fluid system. The sensor assembly comprises a disposable portion, and a reusable portion. A flow restricting element is positioned along a fluid flow passage between an inlet and an outlet. The disposable portion further has an upstream fluid pressure membrane and a downstream fluid pressure membrane. The reusable portion has an upstream fluid pressure sensor and a downstream fluid pressure sensor. The upstream fluid pressure sensor senses the upstream fluid pressure at a location within the fluid flow passage between the inlet and the flow restricting element. The downstream fluid pressure sensor senses the downstream fluid pressure at a location within the fluid flow passage between the flow restricting element and the outlet. The process utilizes output of the sensors to calculate the flow rate of the fluid.

Abstract: An implantable infusion device includes a housing and a collapsible member and an interference member disposed within the housing. The collapsible member defines a reservoir for containing fluid and has an outer surface that moves between an empty position and a full position in response to a change in volume of fluid contained in the reservoir. The interference member is configured to engage the outer surface of the collapsible member as the reservoir approaches the full position and to cause pressure in the reservoir to increase following engagement with the surface of the collapsible member and concomitant fluid introduction into the reservoir. The infusion device further includes a pressure sensor in communication with the reservoir, which can be used to determine whether the reservoir is full by measuring characteristic pressures associated with the interference member engaging the outer surface of the collapsible member and concomitant fluid introduction into the reservoir.

Abstract: The present invention relates to a liquid infusion apparatus, including: a finger module provided in a main body such that the finger module can elastically move backward from a liquid delivery tube; a tube clamp, in which two clamp bodies spaced apart from each other approach each other by means of restoring force of an elastic member upon the opening of a door during infusion, so as to compress and block the liquid delivery tube; and a tube blockage detection device which detects whether the liquid delivery tube is blocked by a cause, for example, when the outlet-side portion of the liquid delivery tube, which delivers medicinal liquid pumped by a liquid pump during infusion, is bent.

Abstract: A pumping device that can be used with currently-available pressure bag infusers is disclosed. The pumping device is hand-held and lightweight. The device is controlled by a microprocessor. Thus constant pressure to the bag is maintained through automatic adjustment of pumping and venting functions. In addition, a novel, new pressure bag infuser and a modified Luer Lock fitting for use with the pumping device are described.

Abstract: A device for displaying information is provided. The device includes data storage circuitry for storing data, a display configured to display data to a user, a processor configured to control the display and the data storage circuitry, and user input circuitry. The processor is configured to control the display based on user input to: graphically display an aggregate period view having at least two period views, graphically display a single period view, graphically display a data type symbol corresponding to a given data type, graphically display at least one data type symbol for every period view, and display a card view including information data corresponding to a selected data type symbol.

Abstract: In order to improve the energy efficiency of an injection device 100, a current is caused to be applied to a motor 113 of the injection device 100, which is related to a signal from a force sensor 115. The signal represents a force that is applied by the motor 113 to a plunger 122 of a cartridge 121.

Abstract: A flow rate assessment protocol (140) that may be utilized by a power injector (10) is disclosed. This flow rate assessment protocol (140) monitors a flow rate (156) during execution of a medical fluid delivery protocol (154). This monitored flow rate is compared with a target flow rate (158). A comparative output of this monitored flow rate and target flow rate is displayed (160), for instance on a graphical user interface (11).

Abstract: A method of programming an ambulatory infusion pump from a computer. The ambulatory infusion pump is programmed to execute a delivery program, and the delivery program is driven by operating parameters. The method comprises generating a table on the computer, the table containing a row, the row having a plurality of cells, each cell in the row relating to a different operating parameter for the delivery program; entering an operating parameter into at least one of the cells; and downloading the operating parameters into the pump.

Abstract: A wearable infusion pump assembly includes a reservoir for receiving an infusible fluid, and an external infusion set configured to deliver the infusible fluid to a user. A fluid delivery system is configured to deliver the infusible fluid from the reservoir to the external infusion set. The fluid delivery system includes a volume sensor assembly, and a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the volume sensor assembly. The volume sensor assembly is configured to determine the volume of at least a portion of the quantity of fluid. The fluid delivery system further includes a first valve assembly configured to selectively isolate the pump assembly from the reservoir, and a second valve assembly configured to selectively isolate the volume sensor assembly from the external infusion set.

Abstract: An infusion pump having a tubing clamping section including a movable and a stationary portion. The infusion pump includes at least one sensor for detecting a contact length of tubing within the movable and/or the stationary portion. The infusion pump includes a shuttle having a shuttle stationary and a shuttle moveable portion, and is configured to squeeze a length of the tubing between the shuttle portions. The infusion pump includes a motor connected to the shuttle moveable portion via a shaft. The motor moves the shuttle moveable portion towards and away from the shuttle stationary portion. The infusion pump includes a controller and an encoder that detects a position of the shaft. The controller converts the detected position into a travel distance of the shuttle moveable portion, and calculates a diameter and a thickness of the tubing based on the travel distance and the contact length of the tubing.

Abstract: A medical device includes a first housing portion (FHP) and a second housing portion (SHP) configured to be to be movable relative to each other from a first position to operatively engage at a second position to couple at least one of a drive device and a needle-inserting device supported by one of the FHP and the SHP to a reservoir supported by the other of the FHP and the SHP. Electronic circuitry configured to detect at least one of a first magnetic interaction between a magnet and at least one of a first magnetically attractive material and a first magnet-responsive device and a second magnetic interaction between the magnet and at least one of a second magnetically attractive material and a second magnet-responsive device, and to provide a signal or a change in state in response to detecting at least one of the interactions.

Abstract: A computer controlled electric syringe includes: a piston unit including a piston being configured to press and move a rubber plug of a cartridge by a second end to discharge a medicinal solution from a cartridge through an injection needle; a ball screw having a screw shaft and a nut portion that is screwed into the screw shaft, the screw shaft being loosely inserted into the hollow portion of the piston through the opening, the nut portion being coupled to the piston; a screw shaft supporting portion rotatably supporting the screw shaft of the ball screw; a rotation preventing portion configured to prevent the nut portion of the ball screw from being rotated; and a piston supporting portion supporting the piston to be movable in an axial direction of the screw shaft along with the nut portion by the rotation of the screw shaft.

Abstract: Methods of conducting thrombectomy procedures and deploying a thrombectomy catheter are disclosed. A thrombectomy procedure is conducted with a thrombectomy catheter deployment system. A drive unit configured to operate an infusion pump is provided. The drive unit is operable according to one or more operating modes. A preconnected and consolidated pump and catheter assembly configured for loading in the drive unit is also provided. The assembly is separate from the drive unit prior to loading. The infusion pump and a catheter of the assembly are in communication prior to loading. The assembly provides one or more digital instructions to the drive unit. The drive unit is operable according to the one or more operating modes referenced by the one or more digital instructions. The assembly is loaded into the drive unit, and the drive unit is engaged to the infusion pump for operation of the infusion pump.

Abstract: The invention relates to an automatic injection device (1) for a product contained in a container (50), comprising: a housing (8, 19) receiving the container (50), the container being movable between an initial position and an insertion position, triggering means (23) for initiating the movement of said container (50) from its initial position to its insertion position, said triggering means (23) being in one of a passive state, in which application of a force on said triggering means does not initiate movement of said container (50), and an active state, in which application of said force on said triggering means does initiate said movement, and a safety shield (10) movable with respect to said housing (8, 19) between a first position and a second position, movement of said safety shield (10) from its first position to its second position placing said triggering means (23) in its active state, characterized in that said device comprises: an indicator (19c, 13) that provides an indication to a user of the

Abstract: A system for clamping a flexible tube containing medical fluids includes a cable assembly coupled to a remote driver and a slidable clamp that imparts a clamping force to the flexible tube. An electrical continuity detector is included to measure the wear of an internal insulating layer of the cable between a sliding inner wire and a cable casing member. An indication of the wear to the cable is generated in response to a comparison of the electrical integrity of the insulating layer with a threshold. The wear indication enables the cable to be repaired or replaced prior to a malfunction of the overall tube clamp system.