Treating Material Introduced Directly Into Liquid Stream Path Patents (Class 604/83)
  • Patent number: 10398838
    Abstract: An auto-injector pen has an outer housing (12, 14) which has a proximal end (18) and a distal end (16), an inner housing (84) having a cartridge (74) therein, the cartridge (74) containing a medicament and having one end thereof sealed by pierceable member (80), a needle hub (64) having first and second piercing tips (68, 70) which are in fluid communication, an actuating assembly (28) which moves an actuator from a first position to an activated position wherein the first piercing tip (68) extends outwardly of the outer housing (12,14) at the proximal end (18) and the second piercing tip (70) pierces the pierceable member (80), a first trigger (22) located at the distal end (16) and a second trigger (98) located at proximal end 18, the arrangement being such that the second trigger 98 must be activated to permit activation of the first trigger (22).
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: September 3, 2019
    Assignee: Duoject Medical Systems Inc.
    Inventors: Yan Tremblay, Sylvain Cloutier, Simon Hamel
  • Patent number: 9925356
    Abstract: A long catheter can be inserted into a patient while eliminating a need for a sterile field by incorporating the long catheter into an infusion tubing and carrying it in with an infusion. The long catheter has a structure that prevents it from leaving the infusion tubing when fully extended and therefore becomes a connector for fluids to transfer down the long catheter by infusion through the infusion tubing. Use of an adjustable seal connector allows the long catheter to be stopped at varying points during insertion and even to allow the long catheter to be reversed by pulling suction on the infusion tubing and retracting the long catheter back into the infusion tubing. The long catheter also remains within sterile confines of the infusion tubing and therefore is prevented from becoming contaminated.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 27, 2018
    Inventor: Matthew Dickson Reavill
  • Patent number: 9764081
    Abstract: A fluid path set including a multi-patient use section adapted for connection with a pump device and a source of injection fluid, and a per-patient use section adapted for removable fluid communication with the multi-patient use section. The per-patient use section includes a pressure isolation mechanism having a first port adapted for connection to the pump device via the multi-patient use section, a second port adapted for connection to a patient, and a pressure isolation port adapted for connection to a source of medical fluid via the multi-patient use section. The per-patient use section includes a valve member biased to a normally open position permitting fluid communication between the first port, the second port, and the pressure isolation port, and movable to a closed position to close the pressure isolation port when fluid pressure reaches a predetermined pressure level sufficient to overcome a biasing force applied to the valve member.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 19, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Frederick W. Trombley, III, David M. Reilly, Alan D. Hirschman, David M. Griffiths, Gerald W. Callan, Luis A. Pedraza, Jennie Kwo, Christopher T. Zirps, Roderick H. Beaulieu
  • Patent number: 9629810
    Abstract: The invention relates to a capsule comprising an inlet and an outlet connected by a passage, in which a dissolvable blocking element and a composition to be orally administered are arranged. The blocking element is fluid permeable and, in a non-dissolved condition, is arranged in the passage to block delivery of the composition to an outlet of the passage. The invention further relates to a method for releasable sealing a capsule comprising a composition to be orally administered, comprising the steps of providing the composition chamber in a passage and filling composition into the composition chamber. The passage formed by the capsule is occluded with a blocking element and the blocking element comprises dissolvable material and has a fluid permeable structure.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: April 25, 2017
    Assignee: SANDOZ AG
    Inventor: Franz Xaver Schwarz
  • Patent number: 9402787
    Abstract: The invention relates to a device for removing a fluid from at least one container (300), from a vial for example, said container being closed by a closure (320) that can be punctured. The device comprises a base body (271) with a container receiving portion (272) and a hollow needle-like puncturing organ (277) in order to puncture the closure (320) of the container (300) in a removal position of the container (300). The aim of the invention is to enable mounting the container on the device without unintentionally puncturing the closure. This is achieved in that detent structures (274, 275) are provided which retain the container (300) on the device in a removal position and in a mounting position which is different from said removal position. Such a device can be used in particular to fill an applicator (280) with one or more fluid reservoirs from one or more vitals.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: August 2, 2016
    Assignee: MEDMIX SYSTEMS AG
    Inventors: William Brem, Ralph Egon Kayser, Andy Greter
  • Patent number: 9233213
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 12, 2016
    Assignee: Janssen Biotech, Inc.
    Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 8968238
    Abstract: Mixing systems and methods include a mixing device comprising a primary tube having a proximal end, a distal end, an outer surface and an inner lumen and at least one secondary tube having a proximal end, a distal end, an outer surface and an inner lumen. The at least one secondary tube is substantially parallel to the primary tube. The distal end of the at least one secondary tube is fluidly connected to the primary tube at a junction located on the primary tube close to the distal end of the primary tube.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: March 3, 2015
    Assignee: Intravenous Solutions, Ltd.
    Inventors: Christopher Page, Stephen Probst, Thomas Corrado
  • Publication number: 20140336610
    Abstract: Methods and devices for delivering variable amounts of a drug formulation directly from a drug delivery device without requiring point of use reconstitution as a separate mixing step are described herein. These methods and devices increase the convenience, speed and simplicity of administration of drug formulations. The devices mix two or more components in a constant mixing ratio effectively simultaneous to administration, and allow for variable doses while retaining the desired ratio of the components in each dose. The devices are particularly useful for administering drug formulations that are unstable at room temperature in liquid form. The methods described herein generally use conventional devices that have been modified to administer an unstable compound and provide acceptable storage stability. Typical devices include infusion sets, pump reservoirs, syringes, pens, vials and cartridges.
    Type: Application
    Filed: April 9, 2014
    Publication date: November 13, 2014
    Inventors: Gerard Michel, Robert Feldstein, Bryan Wilson, Jake Ganem
  • Patent number: 8882698
    Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the pyloric portion of the gastrointestinal system and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device in the pyloric portion and a flexible sleeve that extents into the duodenum. The anchor is collapsible for endoscopic delivery and removal.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: November 11, 2014
    Assignee: GI Dynamics, Inc.
    Inventors: Andy H. Levine, David A. Melanson, John C. Meade
  • Publication number: 20140303591
    Abstract: Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow. The drug pump and/or controllable valve dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow, a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow, and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 9, 2014
    Inventors: Robert A. Peterfreund, Michael Parker, Nathaniel M. Sims, Mark A. Lovich, Harold J. DeMonaco
  • Publication number: 20140276577
    Abstract: Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may utilize a thermochemical reaction between at least two reagents where a first reagent has been preloaded into a catheter while a limiting reagent is circulated through the catheter to react with the first reagent. The resulting chemical reaction may be exothermic or endothermic, and a heat transfer fluid may be used to exchange energy between the chemical reaction and surrounding tissue.
    Type: Application
    Filed: March 6, 2014
    Publication date: September 18, 2014
    Applicant: Gyrus ACM, Inc. (d.b.a Olympus Surgical Technologies America)
    Inventor: Christopher Thralls
  • Patent number: 8800551
    Abstract: A drug delivery device mainly has a housing, which can be easily held and operated. The housing has one end formed with an adjustment seat capable of adjusting a range distance, and the other end connected to a gas pressure control source for providing mainstream and substream gas pressures. Disposed in the housing are a drug delivery pressuring tube, an embedded drug-can connecting seat or an external drug-can connecting seat, a replaceable drug-can container and a gas communication tube. According to this design, the minor liquid drug can be controlled, the drug-can can be replaced and the continuous quantitative injection of drug can be made. Also, all damaged or dirty members of the invention may be disassembled, cleaned or replaced.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: August 12, 2014
    Assignee: Gold Nanotech Inc.
    Inventor: James Tang
  • Patent number: 8747370
    Abstract: An IV manifold includes a plurality of injection/aspiration ports including a needleless access port (NAC). A check valve included in the manifold is generally located between injection ports. A two-way aspiration can be provided by the NAC having a single elongate valve element including a plug at one end. The elongate valve element has properties for resiliently and sealingly biasing the plug into an aperture of the NAC. In use, the plug is mechanically displaced by insertion of a male Luer for injection or aspiration.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: June 10, 2014
    Assignee: CareFusion 303, Inc.
    Inventors: Raymond P. Feith, Tim Truitt, Gary S. Werschmidt
  • Patent number: 8706198
    Abstract: A catheter device comprising a chamber containing an opacity enhancing substance is disclosed. The opacity enhancing substance is in a dried or semi-dried form within the chamber of the device. Release of a liquid into the chamber suspends the substance and forms an opacity enhancing solution that is released into the lumen of the device in order to enhance the opacity of the device for imaging.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: April 22, 2014
    Assignee: Quali-Med GmbH
    Inventor: Eric K. Mangiardi
  • Patent number: 8668662
    Abstract: Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the pyloric portion of the gastrointestinal system and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device in the pyloric portion and a flexible sleeve that extents into the duodenum. The anchor is collapsible for endoscopic delivery and removal.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: March 11, 2014
    Assignee: GI Dynamics, Inc.
    Inventors: Andy H. Levine, David A. Melanson, John C. Meade
  • Patent number: 8652097
    Abstract: A method of combining a drug in a first container and a liquid in a second container includes placing the first container and the second container in fluid communication with a housing, combining the liquid and the drug in the first container, transferring the liquid and the drug from the first container to the housing, and transferring the liquid and the drug from the housing to a third container.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: February 18, 2014
    Assignee: B. Braun Melsungen AG
    Inventor: Freddie Eng Hwee Lee
  • Patent number: 8545440
    Abstract: Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: October 1, 2013
    Assignee: Carticept Medical, Inc.
    Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
  • Patent number: 8529502
    Abstract: A transfer system (100, 100?, 100?) adapted to allow first contents of a first container (20) and second contents of a second container (30) to mix to form a material. The mixed material is retrieved to a syringe (40). The transfer system (100, 100?, 100?) comprises first (17) and second (18) flow control members for controlling fluid flow between the containers (20, 30) and the syringe (40). The invention further relates to a drug mixing kit comprising a container unit containing first and second containers, and a transfer unit comprising ports for receiving the containers and a syringe and a number of flow channels. The container unit and the transfer unit are adapted to be coupled together to form a drug mixing kit.
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: September 10, 2013
    Assignee: Novo Nordisk Healthcare AG
    Inventor: Bo Radmer
  • Patent number: 8480617
    Abstract: The invention relates to an injection device for the needle-free injection of a medium. Said injection device comprises an injector device and an ampoule unit, said ampoule unit comprising a base (4) holding the medium to be injected. Said base comprises a jacket (5) which exerts pressure on the base, and jacket completely enveloping the base in the longitudinal axial direction.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: July 9, 2013
    Assignee: Painless Tech GmbH
    Inventors: Benedikt Lenzner, Stephan Theuer, Bernd Störmer-Talleur, Dirk Schulz
  • Patent number: 8449494
    Abstract: A device and a method for preparing foam are provided. The device includes a first housing having a first chamber therein and a first movable member positioned at least partially within the first housing. The device also includes a second housing having a second chamber therein, the second chamber being selectively and operably connectable to the first chamber. The second housing further includes a biasing member and a second movable member therein, the biasing member biasing the movable member toward a first end portion of the second housing. The device includes a valve operably connected to the first chamber and the second chamber and movably positionable to selectively control the connection between the first chamber and the second chamber and a handle operably connected to the first movable member and movable to bias the first movable member toward a first end portion of the first housing.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: May 28, 2013
    Assignee: Cook Medical Technologies LLC
    Inventor: Jeffry S. Melsheimer
  • Publication number: 20130110038
    Abstract: A countercurrent pushback infusion apparatus includes an infusion pipe, a bag-shaped elastic container, a first blocker, and a second blocker. The infusion pipe has an output end, an input end, and a flow channel interconnecting the output and input ends. The bag-shaped elastic container is set on the infusion pipe and has an interior chamber connected to the flow channel. The first blocker is set on the infusion pipe between the bag-shaped elastic container and the output end and is switchable between a released position and a closed position. The second blocker is set on the infusion pipe between the bag-shaped elastic container and the input end and is switchable between a released position and a closed position. The apparatus allows pushback of blood countercurrent without the detachment of the needle and the infusion pipe, reduces the risk of infection, and increases the convenience of use.
    Type: Application
    Filed: October 31, 2011
    Publication date: May 2, 2013
    Inventor: Chia-Yu Hsu
  • Patent number: 8425464
    Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: April 23, 2013
    Assignee: Carticept Medical, Inc.
    Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
  • Patent number: 8425463
    Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: April 23, 2013
    Assignee: Carticept Medical, Inc.
    Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
  • Patent number: 8419722
    Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: April 16, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Mark Richards, Brian D. Burkinshaw, Kevin Pauza, James B. Rogan, John Wheeler
  • Patent number: 8403882
    Abstract: Disclosed is an applicator device (10) for applying a multi-component fluid, especially a multi-component tissue glue, comprising a plurality of substantially cylindrical supply containers (12) for respectively one component of the fluid to be applied, each supply container (12) having a front end (16) with an outlet opening (18), a rear end (22) opposite to the front end (16), and a slidably displaceable piston (24) arranged within the supply container (12) and having a piston rod (26) extending out of the rear end (22) for operating the piston (24). Moreover, the applicator device includes a manifold (72) having terminal ends (50,58) with a first port for fluid connection with the front ends (16) of the supply containers (12), the manifold (72) further having internal channels (62) extending from the first ports of the terminal ends (50,58) to an outlet site.
    Type: Grant
    Filed: November 22, 2005
    Date of Patent: March 26, 2013
    Assignee: Omrix Biopharmaceuticals, S.A.
    Inventor: Edit Goldberg
  • Patent number: 8403923
    Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: March 26, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza
  • Patent number: 8382704
    Abstract: A system for delivering a cell-slurry to a patient may include a fluid, cells that are non-dissolvable or immiscible in the fluid, thereby forming the cell-slurry, a syringe adapted to contain the cell-slurry and a supernate of the cell-slurry, the syringe defining a first end having an outlet through which the cell-slurry is delivered to the patient, a fluidizing system associated with the syringe and adapted to effect dilation of the cell-slurry with a portion of the supernate, to form a dilated cell-slurry, the dilated cell-slurry being transferred from the fluidizing system to the syringe, while maintaining at least a portion of the supernate, the cell-slurry and supernate being transferred from the fluidizing system to the syringe, a pressurizing mechanism adapted to create a pressure to cause the dilated cell-slurry contained within the syringe to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system, the pressurizing mechanism and movemen
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: February 26, 2013
    Assignee: Medrad, Inc.
    Inventors: Arthur E. Uber, III, David M. Griffiths, David M. Reilly, Alan D. Hirschman, Kevin P. Cowan, Mark Trocki
  • Patent number: 8357147
    Abstract: A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: January 22, 2013
    Assignee: Spinal Restoration, Inc.
    Inventors: Brian D. Burkinshaw, John L. Wheeler, James B. Rogan, Steven I. Whitlock
  • Patent number: 8262607
    Abstract: Devices and methods are provided for delivering fluid components of an embolic mass into a body cavity. A connector, which includes a receiving element, a first port, and a second port, is provided for securing an outer tubular element and an inner tubular element such that the outer tubular element coaxially surrounds the inner tubular element. The first port is in fluid communication with the lumen of the outer tubular element when the outer tubular element is secured to the receiving element; and the second port is in fluid communication with the lumen of the inner tubular element when the inner tubular element is secured to the connector. First and second fluid components of an embolic composition are delivered into the first and second ports of the connector and through the lumens of the outer and inner tubular elements for occlusion of the body cavity.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: September 11, 2012
    Assignees: Stryker Corporation, Stryker NV Operations Limited
    Inventor: Stephen Christopher Porter
  • Patent number: 8257320
    Abstract: An IV manifold includes a plurality of injection/aspiration ports including a needleless access port (NAC). A check valve included in the manifold is generally located at an upstream end of the manifold. However, the check valve may alternatively be located between injection ports. An aspiration port can be formed with a second seal disposed on the side of the valve element opposite a first seal. Two-way aspiration can be provided by a valve having a cage with or without compressible characteristics to accommodate low tolerance fittings. Alternatively, two way aspiration can be provided by the NAC having a single elongate valve element including a plug at one end. The elongate valve element has properties for resiliently and sealingly biasing the plug into an aperture of the NAC. In use the Plug is mechanically displaced by insertion of a male Luer for injection or aspiration.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: September 4, 2012
    Assignee: CareFusion 303, Inc.
    Inventors: Raymond P. Feith, Tim Truitt, Gary S. Werschmidt
  • Patent number: 8252228
    Abstract: A kit is described including at least one container including a predetermined quantity of sterilized biodegradable carriers in a powder form having a treatment agent disposed therein. The kit further includes a delivery device for delivering the predetermined quantity of sterilized biodegradable carriers with the treatment agent disposed therein to a treatment site. In other embodiments, methods are described for producing the sterilized treatment agent loaded biodegradable carriers and delivering the sterilized carriers to a treatment site.
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: August 28, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Abigail Freeman, Thierry Glauser, Paul M. Consigny
  • Publication number: 20120203204
    Abstract: A system and method for intravenous, intramuscular, or subcutaneous delivery of a reconstituted medication fluid with simultaneous, uninterrupted delivery of a primary fluid. A medication fluid is prepared by reconstituting a medication with a primary fluid as diluent. A container adapted to receive a medication is retro-primed with primary fluid from a primary bag. The primary fluid mixes with the medication to reconstitute the medication and form a medication fluid. A medication delivery system and method according to the present invention allows for the continuous infusion of primary fluid both during and after the administration of a reconstituted medication, using a closed system with reduced opportunities for contamination and infection.
    Type: Application
    Filed: September 23, 2011
    Publication date: August 9, 2012
    Inventor: David M. Briggs
  • Publication number: 20120114716
    Abstract: A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a cannula and/or reduced-diameter syringe tip. The pieces are placed into a syringe and wetted, say with a morphogenic solution, and optionally mixed with a bulking material, which is similarly sized to fit through the cannula. The thoroughly mixed and wetted product forms a viscous aggregate which may then be injected into the patient at the target site.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 10, 2012
    Applicant: Warsaw Orthopedic, Inc.
    Inventors: Neil B. Beals, Jeffrey L. Scifert, Scott D. Boden
  • Patent number: 8173066
    Abstract: The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 8, 2012
    Assignees: Forschungsgemeinschaft der DRK Blutspendedienste e.V., Maco Pharma S.A.
    Inventors: Harald Mohr, Wolfram H. Walker
  • Patent number: 8152755
    Abstract: A catheter for delivering a therapeutic agent to a target site of a human or animal subject can include a substantially flexible and biocompatible catheter body having a proximal end and a distal end. An eductor can be located at the distal end of the catheter body, and a first lumen within the catheter body for housing the therapeutic agent can be in fluid communication with the eductor. A second lumen, also in fluid communication with the first lumen, can extend from the proximal end of the catheter body towards the eductor and can have an output port at the distal end of the catheter body. The eductor can be operable to induce the therapeutic agent to flow from the first lumen out of the output port in response to fluid flowing through the second lumen.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: April 10, 2012
    Assignee: Cell Precision LLC
    Inventors: Michael L. Wach, W. Robert Taylor, Jack C. Griffis, III, Raymond P. Vito
  • Patent number: 8079976
    Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: December 20, 2011
    Assignee: Carticept Medical, Inc.
    Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
  • Publication number: 20110295198
    Abstract: The system comprises a transport module (3) in which are housed administration reservoirs (6) each intended to contain a medical treatment fluid, an administration line (7) equipped with a fluid inlet and outlet (8, 9) accessible from the outside of the transport module and to which is connected each administration reservoir, and obturation means (12) associated with each administration reservoir, the obturation means (12) associated with each administration reservoir being moveable between first and second positions in which the corresponding administration reservoir is fluidically isolated and fluidically connected to the administration line respectively, and a preparation and/or administration unit on which the intention is to position the transport module (3), the preparation and/or administration unit including first control means laid out for controlling the displacements of the obturation means (12) associated with each administration reservoir (6) between their first and second positions.
    Type: Application
    Filed: May 24, 2011
    Publication date: December 1, 2011
    Applicant: DORAN INTERNATIONAL
    Inventor: Philippe BUISSON
  • Patent number: 8002736
    Abstract: Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: August 23, 2011
    Assignee: Carticept Medical, Inc.
    Inventors: Timothy Patrick, Richard Knostman, Michael Axelrod, Carribeth Ramey
  • Patent number: 7981081
    Abstract: A method and apparatus for injecting fluid into areas having high density tissue that creates a high backpressure resistance on the injection device is disclosed. The high backpressure resistance is overcome through a mechanical advantage achieved by using a secondary reservoir having a cross-sectional area smaller than the cross-sectional area of a primary reservoir. Exemplary injection device reservoir housings may comprise a primary reservoir, a secondary reservoir, a check valve, a septum penetrating cannula, travel limits, a pen needle connecting portion, sliding seal guide ribs, a sliding seal, a pen needle assembly, a needle stop, and a patient needle.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: July 19, 2011
    Assignee: Becton, Dickinson and Company
    Inventors: Ronald W. Marsh, Mark Follman, Edward P. Browka
  • Publication number: 20110152758
    Abstract: The invention relates to a single-use injector (4) and a dual-chamber system (99), wherein at least one first chamber (105) is part of a cylinder-piston unit (100) that can be received in the single-use injector, and wherein the second chamber (255) is part of a container (250) that can be at least temporarily closed by means of a stopper (257) and that is inserted in a container adapter (200) releaseably supported on the single-use injector. To this end, the plug comprises a plug hole. The container adapter comprises a transfer tube that is closed at first. When the container is inserted in the container adapter, the transfer tube (242) connects the interior of the cylinder-piston unit to the interior of the container.
    Type: Application
    Filed: February 22, 2011
    Publication date: June 23, 2011
    Inventor: Rudolf Matusch
  • Patent number: 7914484
    Abstract: An applicator to be used with first and second liquid-containing syringes comprises an applicator main body for receiving the syringes, a gas flow path adapted to be connected to a gas supply for supplying a gas, a nozzle through which is discharged the gas and the liquids in the syringes, an operation part adapted to be pressed to operate pushers of the syringes, and an opening and closing mechanism in the operation part for shutting off/opening the gas flow path. The opening and closing mechanism is operable to open the gas flow path in synchronization with the pressing operation by the operation part.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: March 29, 2011
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Kenji Yokoyama
  • Patent number: 7875001
    Abstract: A nasal spray apparatus for simultaneously administrating metered amounts of multiple medicaments includes chambers for separately storing incompatible medicaments, such as an antihistamine and a steroid. Reciprocal piston pumps allow the medications to be sprayed into the user's nasal cavity. Two pumps can be used to separately transfer the medicaments to a receptacle where they can be initially mixed just prior to administration. A small volume receptacle is used to reduce the amount of mixture remaining after each stroke of the nasal spray apparatus. A check valve can be associated with each pump to further reduce medicament mixtures from cross contamination within storage chamber preparations. Collapsible components, including collapsible storage chambers or balloon capacitors can be employed to compensate for vacuums and back pressures as the medicaments are pumped to a spray nozzle.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: January 25, 2011
    Inventor: Americo Michael Minotti
  • Publication number: 20100305548
    Abstract: A body portion of the apparatus comprises an interior cavity and a plurality of fluid lumens extending from the cavity to a periphery of the body portion. The apparatus further comprises a first fluid port in fluid communication with a first one of the fluid lumens. The first fluid port is configured to receive a syringe for injecting a liquid diluent and withdrawing a reconstituted liquid medicament. The apparatus further comprises a second fluid port in fluid communication with a second one of the fluid lumens. The second fluid port is configured to receive a medicament vial. The apparatus further comprises a third fluid port at an end of a third one of the fluid lumens for expelling the reconstituted liquid medicament. The apparatus further comprises a stopcock received within the body portion interior cavity and configured to regulate fluid communication between the fluid lumens.
    Type: Application
    Filed: May 26, 2009
    Publication date: December 2, 2010
    Inventor: Timothy Y. Kraushaar
  • Patent number: 7780621
    Abstract: A blood chamber for an extracorporeal blood circuit comprises a blood inlet port (2), a blood containment chamber (3), a first conduit (8) which connects the blood inlet port (2) with the blood containment chamber (3) and which has an end tract (8a) that terminates in the blood containment chamber (3) with a horizontal inlet component. The first conduit (8) comprises a pre-terminal tract (8b) which precedes the end tract (8a) and which has at least a second horizontal component which is directed in an opposite direction to the horizontal inlet component. The blood chamber is used in an arterial line of a dialysis set for guaranteeing a regular and gentle blood flow.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: August 24, 2010
    Assignee: Gambro Lundia AB
    Inventors: Robert Neri, Andrea Paltrinieri
  • Patent number: 7771387
    Abstract: Devices and methods are provided for delivering fluid components of an embolic mass into a body cavity. A connector, which includes a receiving element, a first port, and a second port, is provided for securing an outer tubular element and an inner tubular element such that the outer tubular element coaxially surrounds the inner tubular element. The first port is in fluid communication with the lumen of the outer tubular element when the outer tubular element is secured to the receiving element; and the second port is in fluid communication with the lumen of the inner tubular element when the inner tubular element is secured to the connector. First and second fluid components of an embolic composition are delivered into the first and second ports of the connector and through the lumens of the outer and inner tubular elements for occlusion of the body cavity.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: August 10, 2010
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Stephen Christopher Porter
  • Publication number: 20100106085
    Abstract: The present invention relates to a container (1) comprising:—a body (2) a pusher (5) movable with respect to said body (2) between an “initial position” and an “end-of-use position”—a locker (7) located on said pusher (5) and forming an abutment so as to be able to abut against said body (2) between said “initial position” and “end-of-use position”,—locking means (9, 9h, 8, 5, 4a, 11, 12, 15, 29, 29a, 30a) capable of, temporarily, lock said locker (7) on said pusher (5), in the proximal direction relative to said pusher (5), an as to define a “locker locking position” and, when said pusher (5) abuts against said body (2) via said locker (7), define a “pusher locking position”,—unlocking means (9, 9a, 10, 29, 31, 13, 16, 17, 31) designed so that their triggering causes the release of said locking means so as to allow i) said locker (7) to be displaced proximally relative to said pusher (5) and ii) said pusher (5) to be moved past said “pusher locking position” toward said “end-of-use position”, which container
    Type: Application
    Filed: September 12, 2007
    Publication date: April 29, 2010
    Applicant: BECTON DICKINSON FRANCE S.A.S.
    Inventor: Frederic Perot
  • Publication number: 20100106086
    Abstract: There are provided an intermediate slide valve as well as a plunger slide valve equipped in a syringe in direct contact with injection liquids and a syringe equipped with such slide valves, the injection liquids nor valves being not affected with each other. The intermediate slide valve 10 equipped in the syringe 10 comprises an approximately cylindrical first elastic body 13 and an approximately cylindrical second elastic body 14 which is jointed with one bottom surface 13c of the first elastic body 13, the other bottom surface 13a of the first elastic body 13 and a side surface portion continued therefrom being laminated with a synthetic resin film 15 and the other bottom surface 14a of the second elastic body 14 and a side surface portion continued therefrom be laminated with a synthetic resin film 16.
    Type: Application
    Filed: June 20, 2008
    Publication date: April 29, 2010
    Applicant: DAIKYO SEIKO, LTD.
    Inventors: Masamichi Sudo, Nobuo Sudo
  • Publication number: 20100063440
    Abstract: A liquid mixing and injecting device is provided which includes an upper branch tube, a chamber part and a rubber plug including a slit formed through the body of the rubber plug. A lid member is attached to an open end of the upper branch tube. The lid includes an opening part and a generally cylindrical member. The upper branch tube is occluded by the rubber plug. A male luer part of a syringe can be inserted into the slit to access the chamber part. A rubber plug receiving part is provided for controlling the shape of the lower end part of the rubber plug body when it is deformed to avoid forming a gap where air can accumulate within the flow path. The rubber plug is fixed by fixing an upper fixing piece of the rubber plug to the generally cylindrical member and by fixing a lower fixing piece between the opening part and the generally cylindrical member.
    Type: Application
    Filed: January 25, 2008
    Publication date: March 11, 2010
    Inventors: Ichiro Kitani, Shigeaki Funamura, Norifumi Fujiwara
  • Publication number: 20100056995
    Abstract: A dispensing device for dispensing first and second medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes an adding assembly for controllably dispensing the second medicament to the patient, a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways.
    Type: Application
    Filed: June 3, 2009
    Publication date: March 4, 2010
    Inventor: Marshall S. Kriesel
  • Publication number: 20090318893
    Abstract: An apparatus for use in reconstituting and administering a predetermined medication into a patient's primary IV includes an IV bag containing a first predetermined amount of a predetermined fluid; a disposable pressure for at least partially enclosing such IV bag; means engageable with such pressure bag for applying pressure to such IV bag as directed by a user; a secondary intravenous tubing having a clamp member for permitting and terminating flow of fluids there through operably connectable to such IV bag at a first predetermined location; a plurality of vented cap mini spikes each operably connectable at a first end thereof to at least one of such secondary intravenous tubing, a syringe, and a combination thereof; and a syringe for drawing such reconstituted medicine into an interior portion therein and there after dispelling such predetermined amount of such reconstituted medicine into such patient's primary IV.
    Type: Application
    Filed: June 23, 2009
    Publication date: December 24, 2009
    Inventor: MARY L. ENGLISH