With Particular Wavelength Patents (Class 606/3)
  • Patent number: 9958829
    Abstract: A sensory hologram system includes a holographic system generating a holographic image, a sensory imparting system augmenting the holographic image, a detector configured to detect a location of a target, and a processor synchronizing the holographic system and the sensory imparting system based on the location of the target.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: May 1, 2018
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Aleksandr Y. Aravkin, Lior Horesh, Raya Horesh, Dimitri Kanevsky, James J. Wynne
  • Patent number: 9907975
    Abstract: A method for transdermally treating selected tissue and/or for facilitating the release and/or differentiation of stem cells, including exposing the selected tissue to laser light having a wavelength between approximately 600 and 1400 nm, and maintaining such exposure of the selected tissue or bone to the laser light for a period of time sufficient to deliver a laser light dosage of at least 3 Joules/cm2 per treatment and maintaining such exposure for a period of time sufficient to deliver a laser light dosage of at least 1000 Joules per treatment within a 24 hour period of time. The method also includes upcollimating the laser light such that the laser delivers to the selected tissue a substantially coherent beam of laser light having a cross-sectional area of at least 5 cm2, and, further, delivering the laser light to a depth of at least 5 mm in the selected tissue.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: March 6, 2018
    Inventor: Roger D. Porter
  • Patent number: 9649485
    Abstract: A system and method for treatment of skin including a treatment surface having numerous small energy emitting points for fractional skin treatment as well as negative pressure outlets. During a treatment, negative pressure from the outlets may exert a pulling force on an opposing tissue surface to bring the tissue into contact with the energy points.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: May 16, 2017
    Assignee: Viora Ltd
    Inventors: Danny Erez, Gerard Tal
  • Patent number: 9642746
    Abstract: Methods and systems are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and Schlemm's canal of an eye for reducing elevated intraocular pressure. Some embodiments described apparatus and methods useful in photoablation of tissues. In some embodiments, a photoablation apparatus is used to perforate a tissue, forming an aperture into a space behind the tissue. Gases formed during a photoablation process can be used to pressurize the space behind the tissue to enhance patency of the space. In some embodiments the tissue is the trabecular meshwork of the eye and a wall of Schlemm's canal, and the space behind the tissue is a portion of the lumen of Schlemm's canal. In some embodiments, the method is useful in the treatment of glaucoma by improving outflow from the anterior chamber of the eye into Schlemm's canal, reducing intraocular pressure.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: May 9, 2017
    Inventor: Michael Berlin
  • Patent number: 9474648
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: October 25, 2016
    Assignee: Optimedica Corporation
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 9474649
    Abstract: A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: October 25, 2016
    Assignee: OPTIMEDICA CORPORATION
    Inventors: Daniel V. Palanker, Mark S. Blumenkranz, David H. Mordaunt, Dan E. Andersen
  • Patent number: 9456925
    Abstract: Apparatus and methods of treating a hard lens region of an eye with a laser where one method includes identifying a boundary of the hard lens region, selecting a laser-parameter to enable a photodisruptive procedure in the hard lens region and to control a spreading of bubbles in the hard lens region, modifying a mechanical property of a posterior portion of the hard lens region in a proximity of the identified boundary by the photodisruptive procedure, and modifying a mechanical property of a portion anterior to the modified posterior portion of the hard lens region by the photodisruptive procedure. The laser bubbles can be applied to form incisions which are non transverse to an axis of the eye and intersect the lens fibers.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: October 4, 2016
    Assignee: ALCON LENSX, INC.
    Inventors: Ronald M. Kurtz, Ferenc Raksi, Peter Goldstein
  • Patent number: 9456870
    Abstract: Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: October 4, 2016
    Assignee: Covidien LP
    Inventors: Boris Chernov, Nataliya Chernova, Igoris Misuchenko, Georgy Martsinovskiy, Mikhail Verbitsky
  • Patent number: 9333258
    Abstract: A system and method are provided for minimally-invasive removal of fat from a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength excites the nanoparticles to melt and liquefy fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: May 10, 2016
    Assignees: The Regents of the University of California, eLux Medical, Inc.
    Inventors: Adah Almutairi, Khalid Almutairi
  • Patent number: 9320650
    Abstract: A method for precise working of material, particularly organic tissue, comprises the step of providing laser pulses with a pulse length between 50 fs and 1 ps and with a pulse frequency from 50 kHz to 1 MHz and with a wavelength between 600 and 2000 nm for acting on the material to be worked. Apparatus, in accordance with the invention, for precise working of material, particularly organic tissue comprising a pulsed laser, wherein the laser has a pulse length between 50 fs and 1 ps and with a pulse frequency of from 50 kHz to 1 MHz is also described.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: April 26, 2016
    Assignee: Carl Zeiss Meditec AG
    Inventors: Mark Bendett, Mark Bischoff, Mario Gerlach, Dirk Muehlhoff
  • Patent number: 9308046
    Abstract: A method of treating a subcutaneous fat region is provided. The method includes generating electromagnetic radiation having a wavelength of about 1,200 nm to about 1,230 nm and delivering an average power density of less than or equal to about 2.3 W/cm2 of the electromagnetic radiation to the subcutaneous fat region for at least 300 seconds. The method also includes cooling an epidermal region and at least a portion of a dermal region overlying the subcutaneous fat region for at least a portion of the at least 300 seconds. The method further includes causing necrosis of at least one fat cell in the subcutaneous fat region.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: April 12, 2016
    Assignee: Candela Corporation
    Inventors: Kevin Schomacker, James C. Hsia
  • Patent number: 9295584
    Abstract: Systems and methods to treat a region of a cornea of an eye having an epithelial layer disposed over a stromal layer. The system comprises a device to map a thickness of the epithelial layer over the region of the cornea to generate a map of epithelial thickness over the region, and a laser to generate a laser beam of an ablative radiation. A movable scan component is coupled to the laser to scan the laser beam over the region. A processor system is coupled to the laser and the movable scan component, and the processor system is configured to arrange pulses of laser beam to ablate the epithelial layer of the region in response to the map of epithelial thickness.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: March 29, 2016
    Assignee: AMO Development, LLC
    Inventors: Keith Holliday, Mark E. Arnoldussen
  • Patent number: 9149332
    Abstract: Systems and methods for reconfigurable handheld laser treatment systems are provided. In one embodiment, a reconfigurable handheld laser treatment system comprises: a base unit; a handset that includes a attachment chamber having an attachment aperture, and a laser source arranged to project optical energy into the attachment chamber, the handset coupled to the base unit; an attachment having an adapter interface compatible with insertion into the attachment chamber; a trigger sensor coupled to logic that controls activation of the laser array; and an attachment sensor arranged to detect insertion of the adapted interface into the attachment chamber through the attachment aperture. The logic enables activation of the laser array when the attachment sensor detects an authorized attachment inserted into the attachment aperture. The logic disables activation of the laser array when the attachment sensor fails to detect an authorized attachment inserted into the attachment aperture.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: October 6, 2015
    Assignee: LUMENIS LTD.
    Inventors: Igal Koifman, Uri Voitsechov
  • Patent number: 9138348
    Abstract: An apparatus for operating a laser materials processing and measurement device with a controllable laser for generating a laser beam and beam control means for adjusting the focus zone of a controlled portion of the laser beam in three spatial directions comprises an interface for operating a bidirectional data transfer link with the laser and the beam control means, and user control means for inputting and displaying control commands or control command sequences and for monitoring and/or controlling operation and/or the operating state of the device. So that all the components of the apparatus may also be tested with regard to all functionalities, if the laser materials processing and measurement device is not operationally ready and/or not connected to the interface, according to the invention the apparatus comprises simulation means for simulating operation of the device and/or of the user control means.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: September 22, 2015
    Assignee: Wavelight Gmbh
    Inventor: Mathias Wölfel
  • Patent number: 9107692
    Abstract: Sectioning tools that emit self-sterilizing radiation. In one approach, the radiation is ultraviolet and/or plasmonic.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: August 18, 2015
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward S. Boyden, Roderick A. Hyde, Muriel Y. Ishikawa, Eric C. Leuthardt, Nathan P. Myhrvold, Dennis J. Rivet, Michael A. Smith, Thomas A. Weaver, Lowell L. Wood, Jr.
  • Patent number: 9101377
    Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: August 11, 2015
    Assignee: Biolase, Inc.
    Inventors: Dmitri Boutoussov, Jeffrey W. Jones, Julio Guillermo Cely, Ioana M. Rizoiu, Manvel Artyom Andriasyan
  • Publication number: 20150141968
    Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye tissue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
    Type: Application
    Filed: October 17, 2014
    Publication date: May 21, 2015
    Inventors: Mark S. Blumenkranz, Daniel V. Palanker, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20150141969
    Abstract: A multi-wavelength laser apparatus and methods for laser ablation of tissue are described. The apparatus and methods utilize a laser source emitting at two or more wavelengths coupled to a fiberoptic laser delivery device and a laser driver and control system with features for protection of the laser delivery device, the patient, the operator and other components of the laser treatment system. A fiber tip protection system limits damage to the fiberoptic laser delivery device, thereby allowing the multi-wavelength laser to be operated in a tissue contact mode. The invention, which has broad medical and industrial applications, is described in relation to a method for treatment of benign prostatic hyperplasia (BPH) by contact laser ablation of the prostate (C-LAP) using a technique of touch and pullback laser ablation of the prostate (TapLAP).
    Type: Application
    Filed: November 24, 2014
    Publication date: May 21, 2015
    Inventors: John L. Rink, Marilyn M. Chou, Jasen Eric Petersen, Mark H. K. Chim
  • Patent number: 9032965
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: May 19, 2015
    Assignee: Lumicell, Inc.
    Inventor: W. David Lee
  • Publication number: 20150133899
    Abstract: An apparatus for ophthalmic procedures contains a source of aiming and treatment laser beams, folded mirrors and lens arrays to cause the formation of a static pupil on a delivery mirror for observation and treatment by an operator of the apparatus.
    Type: Application
    Filed: November 3, 2014
    Publication date: May 14, 2015
    Inventor: Jesse Peter Anderegg
  • Patent number: 9028470
    Abstract: A method of treating hypertension in a mammal is described, including: by focused sound energy, heating at least one nerve at a surface of a renal artery in a mammal; during the heating and by magnetic resonance imaging, repeatedly determining thermal levels in each of first and second volumetric zones of a region that includes at least a portion of the surface, the second zone being adjacent to the first zone; after determining that an indicium of a thermal level in the first zone exceeds a first threshold, and upon determining that an indicium of a thermal level in the second zone exceeds a second threshold, ceasing the heating of the at least one nerve for at least three months; and as a result of the heating, lowering a blood pressure in the mammal.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: May 12, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Nassir F. Marrouche, Dennis L. Parker
  • Patent number: 9023019
    Abstract: A steerable laser probe may include a handle, an actuation structure of the handle, a housing tube, an optic fiber, and an optic fiber sleeve. The housing tube may have a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater that the first stiffness. The optic fiber may be disposed within an inner bore of the handle, the optic fiber sleeve, the actuation structure, and the housing tube. The optic fiber sleeve may enclose at least a portion of the optic fiber and the optic fiber sleeve may be disposed within the actuation structure and the housing tube. A compression of the actuation structure may be configured to curve the housing tube and the optic fiber.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: May 5, 2015
    Assignee: Katalyst Surgical, LLC
    Inventors: Gregg D Scheller, Matthew N Zeid
  • Publication number: 20150105714
    Abstract: Devices and methods are discussed directed to the use of a low profile laser ablation catheter for use in laser ablation removal of arterial plaque blockages to restore blood flow in the treatment of arteriovenous fistulas. Also discussed are devices and methods directed to packaging, long term storage and sterilization of liquid core ablation catheters.
    Type: Application
    Filed: October 15, 2014
    Publication date: April 16, 2015
    Inventors: James B. LAUDENSLAGER, Dean S. IRWIN
  • Publication number: 20150105758
    Abstract: A method for endoscopic treatment that performs treatment under an endoscope includes irradiating a subject with first narrow band light having a predetermined peak wavelength, performing mucosal incision on a living tissue after irradiation with the first narrow band light, radiating second narrow band light having a peak wavelength in spectral characteristics in a wavelength band closer to a long wavelength side than the first narrow band light after the mucosal incision, and performing treatment other than the mucosal incision on the living tissue after radiation of the second narrow band light.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 16, 2015
    Applicant: OLYMPUS MEDICAL SYSTEMS CORP.
    Inventor: Makoto IGARASHI
  • Publication number: 20150080863
    Abstract: Systems and methods for treating tissue by concentrating a laser emission to at least one depth at a fluence sufficient to create an ablation volume in at least a portion of the target tissue and controlling pulse width within the picosecond regime to provide a desired mechanical pressure in the form of shock waves and/or pressure waves.
    Type: Application
    Filed: March 13, 2014
    Publication date: March 19, 2015
    Applicant: CYNOSURE, INC.
    Inventors: Richard Shaun Welches, Mirko Georgiev Mirkov
  • Publication number: 20150073396
    Abstract: Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can selectively kill and/or affect at least one bacteria. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 190 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range can be provided.
    Type: Application
    Filed: September 9, 2013
    Publication date: March 12, 2015
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Gerhard Randers-Pehrson, David Jonathan Brenner, Alan Bigelow
  • Patent number: 8974444
    Abstract: A method for welding tissue wounds in an animal. The method comprises joining edges of a tissue wound and irradiating the tissue wound and tissue surrounding the tissue wound with a pulsed laser. The pulsed laser has a laser wavelength in a range of an absorption band of water, elastin and/or collagen in the tissue wound and tissue surrounding the tissue wound. The pulsed laser has a pulse width of not more than picoseconds in order of magnitude to heat tissue surrounding the tissue wound and facilitate bonding of native tissue protein present in the tissue surrounding the tissue wound to achieve tissue repair. The laser wavelength is in a range of between about 800 nm to about 2,700 nm.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: March 10, 2015
    Inventors: Robert R. Alfano, Vidyasagar Sriramoju
  • Publication number: 20150065921
    Abstract: A medical apparatus (300, 400, 500, 600, 700) comprises a heating system (304) for heating a target zone (324) of a subject (320), wherein the energy density in a predefined volume is modeled (338) using a thermal model and a processor (330) for controlling (340) the heating system (304).
    Type: Application
    Filed: March 22, 2013
    Publication date: March 5, 2015
    Inventors: Julia Kristina Enholm, Kirsi Ilona Nurmilaukas, Max Köhler
  • Patent number: 8971997
    Abstract: An infrared fiber-optic device is able to monitor esophageal temperature during an ablation/cryoablation procedure over a volume of interest to sense whether the temperature is too high or too low. The device may include a plurality of optical fibers each with a wide angle lens collectively disposed circumferentially and longitudinally to cover the volume of interest, as the particular region over which undesirable temperature may not be known beforehand. In other examples, the device may include an embedded array of infrared sensors extending sufficiently to encompass a volume of interest. The device may be used as part of a feedback control to regulate and stop operation of the ablation/cryoablation procedure to prevent vessel damage.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: March 3, 2015
    Assignee: The Regents of the University of Michigan
    Inventors: Hakan Oral, Fred Morady
  • Patent number: 8951296
    Abstract: Devices and methods for therapeutic photodynamic modulation of neural function in a human. One embodiment of a method in accordance with the technology includes administering a photosensitizer to a human, wherein the photosensitizer preferentially accumulates at nerves proximate a blood vessel compared to non-neural tissue of the blood vessel. The method can further include irradiating the photosensitizer using a radiation emitter positioned within the human, wherein the radiation has a wavelength that causes the photosensitizer to react and alter at least a portion of the nerves thereby providing a therapeutic reduction in sympathetic neural activity. Several embodiments of the technology are useful for disrupting renal nerves, such as renal denervation, for treating hypertension, diabetes, congestive heart failure, and other indications.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 10, 2015
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Robert J. Melder, Ayala Hezi-Yamit, Christopher W. Storment, Carol M. Sullivan
  • Patent number: 8950406
    Abstract: Methods and apparatus for damaging hair follicles using a series of rapidly-delivered low-fluence pulses of coherent or incoherent light are disclosed herein. In some embodiments, the pulses of coherent or incoherent light have a wavelength or wavelengths primarily in the range between 750 nm and 1500 nm. In some embodiments, applied electromagnetic radiation comprising the rapidly-delivered low-fluence pulses is effective for concomitantly heating both the sub-dermal layer (i.e. the dermis) of the tissue and the hair follicles. In some embodiments, the thermal damaging of the hair follicles is useful for facilitating hair-removal.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: February 10, 2015
    Assignee: Alma Lasers Ltd.
    Inventors: Ziv Karni, Joseph Lepselter
  • Patent number: 8945196
    Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: February 3, 2015
    Assignee: Wayne State University
    Inventors: Maik Huttemann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson
  • Patent number: 8945101
    Abstract: An apparatus and a method are provided for treating a targeted area of ocular tissue in a tissue-sparing manner comprising use of two or more therapeutic modalities, including thermal radiation source (such as an CW infrared fiber laser), operative in a wavelength range that has a high absorption in water, and photochemical collagen cross-linking (CXL), together with one or more specific system improvements, such as peri-operative feedback measurements for tailoring of the therapeutic modalities, an ocular tissue surface thermal control/cooling mechanism and a source of deuterated water/riboflavin solution in a delivery system targeting ocular tissue in the presence of the ultraviolet radiation. Additional methods of rapid cross-linking (RXL), are provided that further enables cross-linking (CXL) therapy to be combined with thermal therapy.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: February 3, 2015
    Assignee: Seros Medical, LLC
    Inventors: Satish V. Herekar, Edward E. Manche, Donald J. Eaton
  • Patent number: 8932338
    Abstract: A noninvasive method of reducing fat from targeted regions of a patient's body by applying low-level laser energy externally through the skin of the patient to the targeted areas. Sufficient laser energy is applied to release at least a portion of intracellular fat into the interstitial space. The released intracellular fat is removed from the body through the body's natural functions. The preferred embodiment uses laser energy at about 635 nm.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: January 13, 2015
    Assignee: Erchonia Corporation
    Inventors: Susan M. L. Lim, Steven C. Shanks, Rodrigo Neira
  • Publication number: 20150011982
    Abstract: Disclosed are medical devices, e.g., surgical sutures, surgical staples, surgical pads, surgical meshes, surgical scaffolds etc., and methods of use at a wound in a patient to facilitate the rapid healing Of the tissue at the situs of the wound with minimal fibrous tissue formation. The devices are arranged to be brought into engagement with tissue adjacent the wound to close the Wound and include a core formed of a piezo-electric material and an outer layer covering the core. The outer layer is platelet derived growth factors. The methods of use of the devices also include applying a local molecular energy production agent to the wound and irradiating the wound with a pulsed infra-red laser beam.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 8, 2015
    Inventors: Hossam Abdel Salam El Sayed Mohamed, Houda Abdul Rahman M. AL Mansour
  • Publication number: 20150005750
    Abstract: Systems, methods, and devices used to treat eyelids, meibomian glands, ducts, and surrounding tissue are described herein. In some embodiments, an eye treatment device is disclosed, which includes a scleral shield positionable proximate an inner surface of an eyelid, the scleral shield being made of, or coated with, an energy-absorbing material activated by a light energy, and an energy transducer positionable outside of the eyelid, the energy transducer configured to provide light energy at one or more wavelengths, including a first wavelength selected to heat the energy-absorbing material. Wherein, when the eyelid is positioned between the energy transducer and the scleral shield, the light energy from the energy transducer and the heated energy-absorbing material of the scleral shield conductively heats a target tissue region sufficiently to melt meibum within meibomian glands located within or adjacent to the target tissue region.
    Type: Application
    Filed: April 29, 2014
    Publication date: January 1, 2015
    Applicant: Tear Film Innovations LLC
    Inventors: Brian S. Kelleher, Kabir Gambhir
  • Publication number: 20150005751
    Abstract: A method and device for cosmetic surgery, especially fat reduction and collagen reformation, by means of a high power laser operating at about 980 nm is presented. The cosmetic surgery method substantially reduces or removes localized lipodystrophies, and essentially reduces flaccidity by localized laser heating of adipose tissue using an optical fiber inserted into a treatment area. The method and device are particularly well suited for treating Lipodystrophies with flaccidity High power laser energy is applied to “fat” cells to breakdown the cell walls releasing the cell fluid. The laser radiation is applied through an optical fiber which is held within a catheter-like device having a single lumen. Traditionally difficult fat cells are treated well. Delicate areas are treated safely. A saline solution may also be inserted into the treatment site to aid in the heating of the fat cells and their eventual destruction as well as their removal.
    Type: Application
    Filed: May 20, 2014
    Publication date: January 1, 2015
    Applicant: Biolitec Pharma Marketing Ltd
    Inventors: Wolfgang Neuberger, Danilo Castro Saurez
  • Publication number: 20140371730
    Abstract: Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a lasing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.
    Type: Application
    Filed: July 25, 2014
    Publication date: December 18, 2014
    Applicant: CYNOSURE, INC.
    Inventors: Rafael Armando Sierra, Mirko Georgiev Mirkov
  • Patent number: 8900219
    Abstract: Systems for visualizing cardiac tissue during an ablation procedure are provided. In general, the systems include an imaging module configured to measure absorbance data at first and second wavelengths wherein the ratio of these absorbance values identifies the nature of the tissue (e.g., lesion, de novo tissue, etc.). The imaging module can also include a video system having at least two chips with corresponding bandpass filters centered at the first and second target wavelengths. The system can also include a processor and/or video monitor for combining the images produced by the various chips, determining treated and non-treated tissue based on the ratio of absorbance values at the target wavelengths, and displaying images of the treatment area. Methods of visualizing cardiac treatment areas during ablation procedures are also provided herein.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: December 2, 2014
    Assignee: Cardiofocus, Inc.
    Inventors: Edward L. Sinofsky, Gerald Melsky, Stephen W. Sagon, Norman E. Farr
  • Publication number: 20140343540
    Abstract: In one aspect, a seismic data acquisition unit is disclosed including a closed housing containing: a seismic sensor; a processor operatively coupled to the seismic sensor; a memory operatively coupled to the processor to record seismic data from the sensor; and a power source configured to power the sensor, processor and memory. The sensor, processor, memory and power source are configured to be assemble as an operable unit in the absence of the closed housing.
    Type: Application
    Filed: November 1, 2013
    Publication date: November 20, 2014
    Inventor: Gabriel Femopase
  • Patent number: 8888767
    Abstract: An improved method and device for safe and efficient medical applications is provided. In a preferred embodiment, based on using the inherent benefits of laser diodes (such as efficient power generation from a reliable and compact solid state device), plasmas and high energy vapors are produced for medical applications with power levels and power densities sufficient to treat medical indications and avoid the creation of extensive damage zones. Transmissions means in different configurations are used to achieve a high power density, which is able to initiate plasma and high-energy vapor at the tip. Once a sparkless plasma and high energy vapor bubbles are formed, it is often found that it will also absorb other wavelengths in addition to the one that initiated it. As a consequence, other wavelengths more efficiently generated by diodes or diode pumped lasers may be added into the beam in order to improve treatment efficiency.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: November 18, 2014
    Assignee: Biolitec Pharma Marketing Ltd
    Inventors: Wolfgang Neuberger, Walter Cecchetti
  • Patent number: 8881735
    Abstract: A laser can produce pulses of light energy to eject a volume of the tissue, and the energy can be delivered to a treatment site through a waveguide, such as a fiber optic waveguide. The incident laser energy can be absorbed within a volume of the target tissue with a tissue penetration depth and pulse direction such that the propagation of the energy from the tissue volume is inhibited and such that the target tissue within the volume reaches the spinodal threshold of decomposition and ejects the volume, for example without substantial damage to tissue adjacent the ejected volume.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: November 11, 2014
    Assignee: Precise Light Surgical, Inc.
    Inventors: Gerald Mitchell, Kenneth J. Arnold
  • Publication number: 20140330258
    Abstract: A medical apparatus comprising a first laser source operable to generate light at a first wavelength and supply a first laser light beam, a second laser source operable to generate laser light at a second wavelength and supply a second laser light beam, the first laser light beam being continuous or pulsed having a first, relatively long pulse duration, the second laser light beam being pulsed with a second, relatively short pulse duration, the apparatus being operable to supply the first laser light beam and subsequently the second laser light beam.
    Type: Application
    Filed: April 1, 2014
    Publication date: November 6, 2014
    Inventor: Yoni IGER
  • Publication number: 20140316386
    Abstract: System and method for making incisions in eye tissue at different depths. The system and method focuses light, possibly in a pattern, at various focal points which are at various depths within the eye issue. A segmented lens can be used to create multiple focal points simultaneously. Optimal incisions can be achieved by sequentially or simultaneously focusing lights at different depths, creating an expanded column of plasma, and creating a beam with an elongated waist.
    Type: Application
    Filed: February 19, 2014
    Publication date: October 23, 2014
    Inventors: Mark S. Blumenkranz, Daniel V. Palanker, David H. Mordaunt, Dan E. Andersen
  • Publication number: 20140316387
    Abstract: Enhanced delivery of compositions for treatment of skin tissue with photoactive plasmonic nanoparticles and light, with embodiments relating to delivery devices using, for example, ultrasound. Treatments are useful for cosmetic, diagnostic and therapeutic applications.
    Type: Application
    Filed: July 1, 2014
    Publication date: October 23, 2014
    Inventors: Todd James Harris, Alice Ann Chen Kim
  • Publication number: 20140296836
    Abstract: The present invention provides methods and compositions for the nanotechnology-based therapy of one or more mammalian diseases. Disclosed are gold-in-porous silicon nanoassemblies that are effective in the targeted and localized treatment of one or more human hyperproliferative disorders, including, for example, cancer of the breast. Methods of systemic administration of these nanoassembly vectors are disclosed that facilitate direct thermal ablative therapy of selected tissues using a localized application of near-infrared energy to the target site, wherein the gold-in-porous silicon nanoparticles release heat to destroy the surrounding cancerous tissue.
    Type: Application
    Filed: March 27, 2014
    Publication date: October 2, 2014
    Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, THE METHODIST HOSPITAL RESEARCH INSTITUTE
    Inventors: Haifa SHEN, Mauro Ferrari, Chun Li, Jian You
  • Publication number: 20140288434
    Abstract: A system for direct imaging and diagnosing of abnormal cells in a target tissue includes a disposable optical speculum and an image acquisition system having the speculum assembled on and mechanically secured thereto. The image acquisition system is arranged to capture at least one of a single image or multiple images or video of cells within the target tissue using at least one of bright field or dark field ring illumination divided into independently operated segments to obtain a plurality of data sets. An image analysis and control unit in communication with the image acquisition system analyzes the data sets and applies algorithms to the data sets for diagnosing abnormal cells.
    Type: Application
    Filed: May 2, 2014
    Publication date: September 25, 2014
    Applicant: Illumigyn Ltd.
    Inventors: Lior Greenstein, Gilad A. Davara, Gad Ganon, David Aviv
  • Publication number: 20140276669
    Abstract: Embodiments of this invention relate to a system and method for performing laser ophthalmic surgery. The surgical laser system configured to deliver a laser pulse to a patient's eye comprises a laser engine that includes a compressor configured to compress laser light energy received, the compressor comprising a dispersion or spectrum altering component provided on a computer controlled stage connected to a computing device. A user providing an indication of a desired pulse width received by the computing device causes the computing device to reposition the stage and the component provided thereon, resulting in a different pulse length being transmitted by the laser engine.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 18, 2014
    Inventor: Gennady Imeshev
  • Publication number: 20140257254
    Abstract: A medical device includes a housing that is moved along a surface of a target tissue in a longitudinal direction. One or more supply lines conduct air and water to the housing. A pulse emitter emits electromagnetic pulses toward the surface at a repetition rate for the pulses to produce ablation holes in the tissue. The pulse emitter includes optical components and is configured to direct the air against the optical components to keep the optical components clean. One or more nozzles emit the water and the air in an air/water spray to moisturize and cool the target tissue prior to laser application.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 11, 2014
    Inventors: Dmitri Boutoussov, Vladimir Netchitailo, Maziar Salehi, Julio Cely, Vladimir Lemberg
  • Publication number: 20140207126
    Abstract: The present disclosure relates to compositions and methods for the treatment of a disease, e.g., cancer or pathogenic infection, using a bioconjugated nanoparticle comprising a biocompatible quantum dot conjugated to a targeting moiety. The targeting moiety allows for the nanopaticle to bind to a cancer cell or pathogenic organism. The quantum dot, upon excitation by soft x-rays, emits electromagnetic radiation at a frequency of ultraviolet light, thereby allowing for the disruption of the DNA found in the cancer cell or pathogenic organism.
    Type: Application
    Filed: November 25, 2013
    Publication date: July 24, 2014
    Applicant: The Boeing Company
    Inventor: Maurice P. Bianchi