Abstract: The invention provides laser methods for treatment and prophylaxis of hemangioma, phlebectasia and other vascular lesions. The methods increase the effectiveness of blood vessel coagulation while diminishing the probability of trauma to surrounding soft tissue. Blood vessels are subjected to a pulse radiation having a wavelength of 500-600 nm and an energy density up to 10 Joules/cm2 for not more than 10 ms, and simultaneously are subjected to at least one more radiation of wavelength in the range of 800-1400 nm and an energy density not exceeding 100 Joules/cm2. The energy density and influence duration for the pulse radiations depend upon the size of the blood vessels to be coagulated. The pulse radiations may be applied either by single pulses with a duration of not more than 10 ms, or by a packet of several nanosecond pulses lasting not more than 10 ms.

Abstract: A photodynamic composition and a method for in vivo photonic treatments that is minimally invasive, versatile and precise are described. The invention allows for photonic treatments with only minimal insertions into the area of treatment, often a single one. The invention may be used with a standard insertion component making the system inexpensive and easy for doctors to use. The invention has applications in several areas of treatment. In vivo treatment of aesthetic skin blemishes such as varicose veins can be performed with minimal external effects. A predetermined amount of a photodynamic composition, as a foam, is injected into the vein or structure of concern. The composition is a sclerosis foam including a photosensitizer. By external compression, where applicable, the photodynamic composition is forced to remain in the vein or structure. After a predetermined time, radiation of appropriate wavelength from a light source is delivered directly to the vascular structure.

Abstract: The invention provides a hand held hair treatment device for the stimulation of hair growth on the scalp, which device comprises: a housing which includes a handle portion and a head portion; a plurality of hollow tines, each tine having a proximal end affixed to the head portion, a longitudinal length extending from the head portion and a distal end terminating in a tip section; a light source disposed within the housing and configured to output light; light guide means for channeling the light from the light source through the tines, and optical devices which are located at the distal ends of the tines; characterised in that the optical devices are configured to spread light which is incident upon them in an outward direction from the distal ends of the tines and onto the surface of the scalp to be treated.

Abstract: The present invention is a method for detecting and destroying cancer tumors. The method is based on the concept of associating a linking protein or linking peptide such as, but not limited to, annexin V or other annexins to single-walled carbon nanotubes (SWNT) to form a protein-SWNT complex. Said linking protein or peptide can selectively bind to cancerous cells, especially tumor vasculature endothelial cells, rather than to healthy ones by binding to cancer-specific external receptors such as anionic phospholipids including phosphatidylserine expressed on the outer surfaces of cancer cells only. Irradiation of bound SWNTs with specific wavelength is then used to detect and destroy those cells to which the SWNTs are bound via the linking protein or peptide thereby destroying the tumor or cancer cells.

Abstract: The present invention relates to an apparatus for cosmetic skin rejuvenation treatment, comprising a continuous wave light source accommodating a high-intensity discharge lamp (104; 204; 304; 604) which has at least one predominant spectral peak between 600 and 700 nm.

Abstract: The present invention is embodied in a medical device which is comprised of a thermal energy delivery component, for example, including an elongate optical fiber terminating in a lateral laser energy emitter, and an outer coolant component, which includes a cannula for receiving the thermal energy delivery component, which terminates in an energy-transmissive balloon for surrounding the thermal energy emitter and providing a tissue-contacting coolant chamber. The cannula portion of the coolant component is moveably sealed around the laser energy delivery component. In one embodiment, a retaining means prevents the thermal energy delivery component from being detached from the coolant component. In an alternate embodiment, there is no retaining means, allowing the more costly thermal energy delivery component to be removed, sterilized and later reused, whereas the less costly outer coolant component, which contacts tissue, blood and body liquids, can be discarded after use.

Abstract: A method and an apparatus for the treatment of either endo-cavital infections or abnormal surface tissue conditions, particularly destructive bacterial infections, post major invasive surgery abscesses and skin infections such as vitiligo and psoriasis. If required, a catheter system is used, which allows the simultaneous drainage of an infected locus and irradiation of the infected locus with laser-generated pulsed ultraviolet light. The laser light wavelength is chosen so as to require radiation, which is lethal to the microorganisms causing the infection, at the lowest possible dose which will provide ameliorative therapty. Alternatively, a diode-pumped solid state Raman laser device is used which can be configured to provide in sequence a selected number of output wavelengths in the ultraviolet spectral range.

Abstract: A therapeutic coiffuring instrument has a light source disposed with the therapeutic coiffuring instrument to produce light selected to produce therapeutic effects to scalp and hair. Elongate members forming part of the instrument are configured to contact hair and scalp and to conduct the light from the source of light into contact with the hair and scalp.

Abstract: A handheld probe treats acne and other skin conditions using a combination of optical and thermal therapy. The device contains light emitting devices capable of impinging a treatment area with laser light. In the preferred embodiment, the light emitting devices emit a combination of red and blue light to treat acne causing bacteria and prevent inflammation. The emitted light can be formed into therapeutically effective shapes by one or more optical arrangements. The device also contains a thermally conductive plate heated by a heater. The thermally conductive plate contacts the skin and warms it, enlarging the pores in the treatment area. One or more contact switches activate the device when brought into or near contact with the treatment area. In the preferred embodiment, the device is powered by a rechargeable battery.

Abstract: Apparatus and methods for removing hair and/or devitalizing follicles using electromagnetic energy to actively target and treat a hair and/or a follicle are disclosed. The electromagnetic energy can be of a selective or non-selective wavelength.

Abstract: A light emitting device for providing therapy to a user includes a light source configured to generate optical energy having a wavelength in a range of from about 400 nm to about 1100 nm. The device further includes a user interface configured to be placed into contact with a treatment area on a user's body and configured to transmit the optical energy from the light source to the treatment area generally along a beam propagation axis. The user interface includes an electrical impedance sensor configured to determine when the user interface is contacting the treatment area. The device also includes a controller, configured to receive at least one sensor signal from the electrical impedance sensor, wherein the controller is configured to prevent activation of the light source based upon the at least one sensor signal.

Abstract: The present invention relates to the process of selectively exposing matter to a specific wavelength of electromagnetic energy in sufficient flux density per wavelength to cause or promote a desired effect. The process includes, but is not limited to, destroying, disinfecting, denaturing, disinfesting, disrupting, or dehydration of one or more of the substances present. More specifically, present invention relates to subjecting matter, which may contain a mixture of substances, to electromagnetic energy, in concurrence with its spectral properties to exploit the spectral differences within the substance or within a mixture of substances. Energies are applied to cause wavelength-dependent reactions resulting from differential absorption; this additional applied energy manifests itself in changes, or quantum transitions, in the vibrational, rotational, magnetic, and electronic states of the molecules.

Abstract: In one aspect, a wound management system is provided. The wound management system includes a multi-lumen cannula adapted to be disposed in a wound site. The multi-lumen cannula includes (1) a fiber optic light distribution system adapted to irradiate the wound site with light; (2) one or more catheters adapted to deliver a fluid to the wound site; and (3) one or more evacuation lines adapted to remove fluid from the wound site. Numerous other aspects are provided.

Abstract: Optical ear infection treatment device and methods are described where an LED and optical light pipe are used to deliver the light from the LED to the middle ear of a patient to reduce bacterial growth and/or eliminate bacteria. Typically, the device is placed in the ear and then activated by the user by pressing an activation button. Once activated the control electronics will turn on the LED and perform a treatment. The most basic treatment mode comprises turning on the LED at maximum power for a predetermined period, e.g. 30 minutes, 60 minutes. When the preset duration is completed, the device will notify the user by an audible beep or vibration that the treatment is complete. Once completed, the user can remove the device, the treatment could be repeated once a day or for extreme cases multiple times during the day.

Abstract: A laser energy delivery device is provided that is suitable for irradiating a body tissue with relatively long wavelength laser energy in the presence of an aqueous liquid without significant absorption of the laser energy by the liquid. The device includes an elongate hollow sheath that has an open aperture at its distal end portion and closed at its proximal end, a laser energy conduit such as an optical fiber or hollow wave guide, within the sheath, the distal end of the conduit being disposed near the open aperture at the distal end portion of the sheath, and the proximal end of the conduit being adapted for connection to a source of long wavelength laser energy. The sheath also includes an inlet port, spaced from the proximal end of the sheath, and adapted to receive and deliver a biologically compatible gas through the sheath to a body tissue site in contact with the open distal end of the sheath.

Abstract: A method for precise working of material, particularly organic tissue, comprises the step of providing laser pulses with a pulse length between 50 fs and 1 ps and with a pulse frequency from 50 kHz to 1 MHz and with a wavelength between 600 and 2000 nm for acting on the material to be worked. Apparatus, in accordance with the invention, for precise working of material, particularly organic tissue comprising a pulsed laser, wherein the laser has a pulse length between 50 fs and 1 ps and with a pulse frequency of from 50 kHz to 1 MHz is also described.

Abstract: The present invention provides method and apparatus for treating tissue in a region at depth by applying optical radiation thereto of a wavelength able to reach the depth of the region and of a selected relatively low power for a duration sufficient for the radiation to effect the desired treatment while concurrently cooling tissue above the selected region to protect such tissue. Treatment may be enhanced by applying mechanical, acoustic or electrical stimulation to the region.

Abstract: The invention is a device for examining the anterior and the posterior segments of the eyeball in a patient's eye, including a stereoscopic microscope system and an oscillating slit lamp disposed downstream of the stereoscopic microscope in the viewing direction in longitudinal direction to two parallel optical beam paths. The invention in the region between the binocular tube objective system and the main objective provides an optical deflection means which does not optically interfere with the stereoscopic beam paths of the stereoscopic microscope and via which an observation beam path and an illumination beam path of an ophthalmoscope can be coupled in in such a manner that the optical observation beam path and the illumination beam path deflected by the optical deflection means each pass through the main objective in viewing direction.

Abstract: A device/system and a method for the treatment of varicose veins and other vein abnormalities are presented. In one preferred embodiment, the treatment comprises a combination of two wavelengths to effectively occlude abnormal veins. The wavelengths are chosen as the effective absorption peaks of hemoglobin and water, which are seen at these wavelengths, approximately 980 nm and 1460 nm respectively. The vein is targeted with these wavelengths to obtain maximum and effective absorption. The Near Infra Red laser radiations are delivered to blood, collagen and water in the vessel which results in occlusion and shrinkage of the vein. In this technique an optical fiber is inserted into the vein and laser sources are used to irradiate the vein. A control mechanism allows delivery of constant power density based on feedback about speed of fiber withdrawal and local structural vein parameters.

Abstract: Provided herein are methods and compositions useful for the treatment of periodontal disease exploiting optical and thermal emissions of near-infrared laser systems and fibers in order to target chromophore-stained biofilm while minimizing damage to healthy tissues.

Abstract: Apparatus for measuring the oxygen saturation level of blood at an internal measurement site in a human or animal patient by reflectance pulse oximetry, comprising first and second light sources (5, 10), a first optical fibre (30) for transferring light from at least one said light source to the internal measurement site (35), at least one receiver (45), for receiving light from the first and second light sources, at least a second optical fibre (40) for transferring light reflected from the region of the measurement site to the receiver, and means for determining the oxygen saturation level of the blood at the internal measurement site, based on the light produced by the light sources and light received by the receiver. The optical centres of the optical fibres are separated from one another by at least 1 mm at their distal ends. The apparatus can be used in combination with a cranial axis bolt for measuring the oxygen saturation level in the brain tissue of a human or animal patient.

Abstract: The present invention provides improved methods and apparatus for skin treatment. The apparatus includes multiple sources of optical energy or several blades that are scanned along a region of skin to form micro-line patterns of damaged tissue. The micro-lines are small in at least one dimension, having a width of less than about 1 mm, and the wounded regions promote beneficial results by stimulation of wound healing and tissue remodeling.

Abstract: An apparatus for laser depilation according to the present invention uses a semiconductor laser diode, which is controlled in respect of its energy level, thereby permitting an economical, effective and safe cosmetic treatment. The power output of light of the semiconductor laser diode ranges from 5 to 1500 mW, and the peak wavelength ranges from 600 to 1600 nm. The controller of the semiconductor laser diode comprises pulsating power output control means and radiation period control means for setting a desired length of time for radiation. With these control means the energy level of the beam of light from the laser may be so controlled that a strong beam of light may be thrown for a relatively short time, or that a weak beam of light may be thrown for a relatively long time. Thus, hairs of different thickness and colors can be removed.

Abstract: A laser treatment apparatus for performing treatment by irradiating an affected part with a laser beam comprises: a laser source capable of emitting beams of a plurality of different wavelengths; a first setting unit which sets an irradiation amount of a laser beam for treatment of a wavelength to be used for treatment; an emission amount changing unit which changes an emission amount of the beam in plural levels; an attenuating unit which attenuates the beam emitted by the laser source; and a control part which controls the emission amount changing unit and the attenuating unit based on the set irradiation amount of the treatment beam.

Abstract: The invention refers to a device for laser surgery comprising a laser and means for coupling laser light of the laser into an optical fiber, wherein the laser is a solid-state layer, which may emit laser light which at maximum intensity has a wavelength in the ragne of 1100 and 1400 nm, wherein the laser has an output power of at least 25 W.

Abstract: Skin disorders such as, for example, atopic dermatitis, dyshidrosis, eczema, lichen planus, psoriasis, and vitiligo, are treated by applying high doses of ultraviolet light to diseased regions of a patient's skin. The dosage exceeds 1 MED, as determined for the particular patient and may range from about 1 MED to about 20 MED or higher. The ultraviolet light has a wavelength within the range of about 295 nanometers to about 320 nanometers. High doses of ultraviolet light are restricted to diseased tissue areas The skin can be cooled prior to and/or during exposure to UV light to minimize tissue damage resulting from exposure to the UV light. Higher doses of UV light can therefore be employed without injurious affects.

Abstract: The acne treatment devices use an array of LEDs, which emit monochromatic light substantially at a wavelength of 405 nanometers, which is coincident with the peak absorbance of light by acne porphyrins. The emitted light is directed from the light source to an acne area of the skin. The device can either be hand-held, with the LEDs mounted on a handle portion, or an LED can be mounted on a patch-like mounting element, which is adapted to be secured to the skin for longer exposure at less intensity.

Abstract: Disclosed herein is a novel method of treating vitiligo by using an excimer laser that emits light in the UVB range. The invention includes a method of incrementally increasing exposure of affected vitiligo areas with UVB laser light from an excimer laser to restore pigmentation to skin areas afflicted with vitiligo.

Abstract: The present invention relates to a devices and methods for killing and/or debilitating pathogenic microorganisms in or on a patient's body, such as light-sensitive bacteria including helicobacter pylori and/or propionibacterium acnes. A chemiluminescent light source provides electromagnetic radiation having predetermined wavelengths in the visible spectrum. The light wavelengths are selected for absorption by naturally-occurring photosensitive chemicals produced by the patient's body.

Abstract: Laser radiation delivered to a treatment area causes vaporization of a substantially greater volume of tissue than the volume of residual coagulated tissue. The laser radiation may have a wavelength of about 300 nm to about 700 nm, may be used with a smoke suppressing irrigant, may have an average irradiance greater than about 5 kilowatts/cm2, and may have a spot size of at least 0.05 mm2. A laparoscopic laser device, for use with an insufflated bodily cavity, may include an elongate body adapted for insertion into an insufflated bodily cavity. A laser energy delivery element, at the distal end of the elongate body, may be coupleable to a source of tissue-vaporization-capable laser energy and capable of delivering laser energy along a laser energy path extending away from the laser energy delivery element. A smoke-suppressing liquid pathway, extending along the elongate body to an exit opening at the distal end, may be coupleable to a source of a smoke-suppressing liquid.

Abstract: A system and method for the treatment of a skin comprising. The system comprises an applicator having a cavity and one or more light sources configured to irradiate the cavity with optical energy simultaneously from at least two directions. The applicator is applied to the skin and a region of skin is made to protrude into the cavity. The protruding region of skin is then irradiated with optical energy from the one or more light sources simultaneously from at least two directions.

Abstract: An ophthalmic laser treatment apparatus which irradiates a laser beam to a patient's eye to be treated is disclosed. The apparatus includes: a first optical fiber which delivers a first laser beam emitted from a first laser source; a first light delivery optical system which forms an image of an emission end surface of the first optical fiber on the affected part of the eye in a predetermined first spot size being in a range of 50 ?m to 1000 ?m; a second optical fiber which delivers a second laser beam emitted from a second laser source; and a second light delivery optical system which forms an image of an emission end surface of the second optical fiber on the affected part of the eye in a predetermined second spot size in a range of 500 ?m to 7000 ?m.

Abstract: Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the treatment of acne and acne scarring by treating sebaceous oil glands and the surrounding tissue with an exogenous chromophore composition and then exposing the target tissue to visible, infrared, or ultraviolet light to inhibit the activity of the oil gland and eliminate acne bacteria. The treatment method of the present invention may be futher augmented by enhancing the penetration of the topical composition into the oil gland and surrounding tissue through the use of procedures including enzyme peeling, microderm abrasion, or ultrasound.

Abstract: A phototherapy apparatus for the treatment of psoriasis which includes a dielectric-discharge excimer lamp 32, which is equipped with a reflector 34 and optical system 36 for ensuring a substantially uniform density of energy, is mounted on a maneuverable arm 40. The arm 40 is mounted to a stand 24. An electronic control unit 20 and a radiofrequency power supply unit 22 are connected to the lamp 32. A pipe of a cooling circuit 9 is connected to the lamp 32 via the arm 40. The pipe 9 connects to an air-liquid exchanger 3 with a de-ionizer having a temperature sensor 5 and a sensor 7. The sensors 5, 7 and 10 are connected to a microcontroller 12, which is connected to an operating panel 14 and to a display 16 and a printer 18. A hardware container 26 is provided on the stand to hold the radiofrequency power supply unit 22, the printer 28, the microcontroller 12, the control panel 30, and the air-liquid exchanger 3.

Abstract: A hand held device generates a predetermined number of pulses of light having a predetermined electromagnetic spectrum, a predetermined duration, a predetermined inter-pulse interval, and a predetermined total energy. The pulse sequence is delivered to a skin surface to temporarily remove hair. A period of time for reappearance of hair on the selected skin surface after the using of the device to remove hair from the selected skin surface is determined by counting the days to hair reappearance after a test light application. Subsequently, the device is used periodically to apply the pulses of light to the selected skin surface at intervals of shorter length than the determined period of hair regeneration, thereby temporarily maintaining the selected skin surface free of visible hair.

Abstract: An apparatus and method to apply photo-stimulation, photo-dynamic therapy and/or ablation laser treatment to biological tissue. The apparatus includes a plurality of radiation energy sources, preferably laser beams. Additionally, the apparatus allows either a single wavelength or a combination of various wavelengths, either coincidentally or adjacently, to be utilized to achieve a desired treatment effect. Laser beams are transmitted to the treatment area by one or more fiber optic cables which terminate at an assembly structured to collimate the emitted radiation prior to application to the tissue. In addition, the apparatus includes a focal length setting mechanism which assures that a constant, fixed distance exists between the point of discharge of the laser beam and the biological tissue, thus assuring a constant energy density at the point of application. A method is presented for applying photo-stimulation, photocollagen stimulation and/or ablation laser treatment utilizing the above apparatus.

Abstract: Multiple hygienic effects are concurrently applied to structures of body cavities. This is established by two or more light sources each capable of delivering a light beam to the structures using optical pathways whereby each light beam provides a unique hygienic effect to the structures. The device could be a handheld device with detachable components. The device could include a massaging mechanism and/or a vibrating mechanism. An agent could be used to the body cavity to assist in the hygienic treatment plan. A cradle could be included to store the device, reload the power supply of the device, as well as a means to communicate with a hygienic service provider. The cradle could also host a display and a selector. A test mechanism could be included to test a performance of the device or to calibrate components of the device.

Abstract: A long pulse alexandrite laser for treating dermatological specimens is disclosed. The use of alexandrite allows operation in the near-infrared, specifically in a 50 nm range surrounding 755. Infrared in this range allows good penetration while still achieving an acceptable ratio of hemoglobin to melanin absorption In addition, a method and related system for treating biologic tissue with pulse light includes generating a long effective output light pulse comprising a series of sub-pulses having a fractional duty cycle over a selected effective pulse duration, a periodicity that is less than the thermal relaxation time of a targeted structure, and an interpulse-delay between successive sub-pulses that is greater than the thermal relaxation time of non-targeted structures within the treatment area; and delivering the output light to the tissue of a patient.

Abstract: Method and apparatus to treat unwanted dermatological conditions on a specific area of the body. The area of treatment is exposed to a specific pattern of multi-wavelength light which may have an added infusion of a particular wavelength from a unique non-collimated laser rod optical insertion. The light is generated by specific gas mixture multiple flashlamps that allow simultaneous, overlap, or consecutive firing with quasi-logarithmic spacing between pulses. Pre/Post low level optical heating increases lesion temperature to optimize pulsed treatment. The optimum fixed specific wavelength distribution pattern allows the treatment of various skin conditions by adjusting the intensity of light, and delay between pulses. The need for skin cooling and damage to skin treatment areas is eliminated by the quasi-logarithmic pulse spacing in conjunction with optimum length and characteristic shape of the individual pulses of light.

Abstract: Aging or damaged skin is treated by irradiating affected skin areas with an effective amount of visible light emanating from an optical apparatus and having a wavelength of about 400 nm to about 500 nm. A light source may be sunlight or artificial light, coherent or noncoherent, pulsed or continuous, of high or low energy, exposed generally or directed to target areas, or any combination of these. In one embodiment, light-emitting diodes are applied directly to discrete skin areas as needed as patches or thin sheets such as pliable masks. Green light (about 500 to about 590 nm) may be used as adjunct therapy with blue/violet light in some embodiments. Compositions containing compounds that enhance light penetration of the stratum corneum such as ?-hydroxy acids (e.g., glycolic acid) and/or filter light may be applied to the skin prior to or during phototreatment.

Abstract: A method for photoselective vaporization of uterine tissue includes delivering laser radiation to the treatment area on the tissue, via an optical fiber for example, wherein the laser radiation has a wavelength and irradiance in the treatment area on the surface of the tissue sufficient because vaporization of a substantially greater volume of tissue than a volume of residual coagulated tissue caused by the laser radiation. The laser radiation is generated using a neodymium doped solid-state laser, including optics producing a second or higher harmonic output with greater than 60 watts average output power. The delivered laser radiation has a wavelength for example in a range of about 200 nm to about 650 nm, and has an average irradiance in the treatment area greater than about 10 kilowatts/cm2, in a spot size of at least 0.05 mm2.

Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900–930 nm, 1190–1220 nm, 1700–1730 nm, or 2280–2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.

Abstract: An Intense Pulsed Light apparatus for cosmetic or therapeutic treatment of the skin having a light source is provided with a light guide having an entry face in a rigid light guide component and an exit face in a flexible light guide component adapted to conform to highly curved parts of the body of a patient.

Abstract: A method and apparatus are provided for Raman imaging of carotenoids and related chemical substances in biological tissue, such as macular pigments. The method and apparatus utilize the technique of resonance Raman spectroscopy to produce an image of the levels of carotenoids and similar substances in tissue. In this technique, light is directed upon the area of tissue which is of interest such as the retina of an eye. A small fraction of the scattered light is scattered inelastically, producing a carotenoid Raman signal which is at a different frequency than the incident light. The Raman signal is collected, filtered, and analyzed to determine the spatial position and intensity of the Raman signals in the inelastically scattered light. An image of the Raman signals is then produced on an output device, with the image representing the spatial distribution and concentration level of carotenoids in the tissue.

Abstract: Laser tissue welding can be achieved using tunable Cr4+ lasers, semiconductor lasers and fiber lasers, where the weld strength follows the absorption spectrum of water. The use of gelatin and esterified gelatin as solders in conjunction with laser inducted tissue welding impart much stronger tensile and torque strengths than albumin solders. Selected NIR wavelength from the above lasers can improve welding and avoid thermal injury to tissue when used alone or with gelatin and esterified gelatin solders. These discoveries can be used to enhance laser tissue welding of tissues such as skin, mucous, bone, blood vessel, nerve, brain, liver, pancreas, spleen, kidney, lung, bronchus, respiratory track, urinary tract, gastrointestinal tract, or gynecologic tract and as a sealant for pulmonary air leaks and fistulas such as intestinal, rectal and urinary fistulas.

Abstract: A method and apparatus for removing hairs from living skin is provided involving the measurement with a colorimeter of the color of the area of the skin where the hair is to be removed to obtain a representative color value, employing the color value to select an optimum range of laser energy necessary to inactivate hair follicles in the area, yet minimize any inflammatory reaction, and directing laser energy of optimum range at the skin area to depilate such area.

Abstract: A method of selectively enhancing photothermal sebaceous gland disruption and treatment of acne is disclosed. The method provides for alleviation of the acne symptoms as well as preventing acne recurrence and new acne from occurring.

Abstract: An apparatus for aesthetic manipulation of the skin having a large pulsator with plurality of light emitting diodes of at least two different wavelengths and a small pulsator with one light emitting diode is disclosed. A frequency modulator automatically modulates the emitting frequency of the tight emitting diodes to a plurality of different frequencies. A power output modulator is provided to modulate the power output of the light emitting diodes. A phase switching subsystem allows selection between a plurality of operating phases, each operating phase operating the frequency modulator and power output modulator in a different predetermined manner. Calibration subsystem connected in circuit with the light emitting diodes calibrates the power output of the light emitting diodes. A vibrator is provided to vibrate the large pulsator. A vibration switching subsystem selectively activates the vibrator.

Abstract: In photodynamic diagnosis and photodynamic therapy, the oscillating wavelength of laser light from a light source is fitted to a plurality of different kinds of photosensitizers and exciting conditions thereof. Moreover, diagnosis and treatment are achieved using concurrent diagnosis during treatment is realized as well. A semiconductor laser generates laser light having an oscillating wavelength which is variable and a full width at half maximum which is narrow. A light transmission line guides an irradiated laser light to the vicinity of a focus, an image transmission line observes the focus and the periphery thereof, a fluorescence light extracting device extracts only the fluorescence light emitted from a photosensitizer excited by the irradiated laser light, an image-pick-up/analyzing device picks up and analyzes an image of the extracted fluorescence light and an image display device displays the analyzing result.

Abstract: A method for the treatment of wrinkles on human skin, by stimulating collagen growth beneath the epidermis layer, comprising the steps of: arranging a pulsed dye laser generator in light communication with a pulsed dye laser delivery device. The pulsed dye laser delivery device is applied against tissue having wrinkles. The pulsed dye laser generator generates a pulsed dye laser light. A pulsed dye laser light from the pulsed dye laser delivery device is directed onto the tissue, to reach hemoglobin in a collagen layer up to about 1.2 mm. beneath the surface of the tissue to effect growth changes therein.